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    <accession>M5FND1</accession>
    <name>M5FND1_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624133.1">
        <property type="nucleotide sequence ID" value="XM_040769362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FND1"/>
    <dbReference type="GeneID" id="63684424"/>
    <dbReference type="HOGENOM" id="CLU_2497859_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9326" checksum="193550F7C190B99E" modified="2013-05-29" version="1">MVFVTTVKGFHNAPTCAEDVKTLSRVEESQDDDIDDNSVMHALLGAMGMDKNLIPPYPPSTKTVNELLVAPHKTPVSLELTLISSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNP3</accession>
    <name>M5FNP3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624658.1">
        <property type="nucleotide sequence ID" value="XM_040773836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNP3"/>
    <dbReference type="STRING" id="1858805.M5FNP3"/>
    <dbReference type="GeneID" id="63688898"/>
    <dbReference type="HOGENOM" id="CLU_042555_4_0_1"/>
    <dbReference type="OMA" id="SVHPAWN"/>
    <dbReference type="OrthoDB" id="14446at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061672">
        <property type="term" value="C:glutathione hydrolase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008242">
        <property type="term" value="F:omega peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000060">
        <property type="entry name" value="Related to DUG3-probable glutamine amidotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="39418" checksum="8B67F14984B61515" modified="2013-05-29" version="1">MCRFLIYKGTEPIQLCHLLTRPAHSIINQAFDSRLRLDTRRPINGDGFGVGWYDKEVDEEMGRQPCIFTSVTPAWNNINLIRLAEKIKSPLVFAHVRATTAGTLSLDNCHPFQFKQLMWMHNGELAGFIKYKRRLQSSVPDEIYEKVLGNTDSEWAFALFLSLLSDINATSFTYKELQKTMLATIAKLNEIAREAGVTEPSLMNFAVTDGATVVATRYISSKTEEAASLYFSSGTTFSETSRGHYKMSKRDKREDIVVIASEPLTFEKADWLELKTNTLIVITPKMNLLQIPIVDEFHVPPADAVLHRRATSFVQEKGLLSPRLVAMTAGIGDLSLAPIEMTAPAQNVPFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP37</accession>
    <name>M5FP37_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GroES-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_85505</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623681.1">
        <property type="nucleotide sequence ID" value="XM_040776738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP37"/>
    <dbReference type="STRING" id="1858805.M5FP37"/>
    <dbReference type="GeneID" id="63691800"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OMA" id="KCSSRCA"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF2">
        <property type="entry name" value="DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="5">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="252"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT96783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="45087" checksum="E310868F548CFEB6" modified="2013-05-29" version="1">MALPQTNTVVRIHPGKLADIRVEQLPTPTIEHPDDAIVKVLKAGLCGSDLHAYRGLEPFTEPYICGHELIGEVVALGSAFGQEVEGRPALYGKLKVGDKVVSPFTCSCEECHFCRIGFPSRCVHSLLFGSPYLPGAQAQYARIPKAGGTLFLLPPSLPADMPEESFMLCGDILPTGYFAALQALGHPNVAPIIRGESYPGVMGAIVPRVQEEGTRVIKEDQKLGVAIVGLGPVGICGLVALLDILSQANVQTYKVYAVDPVPARRAKALAILKKMKPEEAAHVEVLDIEEAKEKVTKETVKGCDAVLEIVGNDSALVLAYDLLRPFGVISSVGVHTSPQFPLNGDTLYTKNVSASFGRCPVRAMFPLAVDLLVRRRDVLAGVGGEEALVERVIPMSEAVEGYEKFDSRVWGKVVFDPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP52</accession>
    <name>M5FP52_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_24696</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625118.1">
        <property type="nucleotide sequence ID" value="XM_040773798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP52"/>
    <dbReference type="STRING" id="1858805.M5FP52"/>
    <dbReference type="GeneID" id="63688860"/>
    <dbReference type="HOGENOM" id="CLU_488344_0_0_1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF8">
        <property type="entry name" value="HOMEOBOX PROTEIN CEH-62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="30"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="89"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="558" mass="59717" checksum="54882668EFA9FB54" modified="2013-05-29" version="1">MTVIRSERPTAVRRGSLPVVCETFSDLQDRKSRRTKYTGDQRDVLEDVYNGDMYPSTTFKRELAGLLHLTNKQVQIWFQNRRSKDKLEAAAAGLPVPSRRRNSSARLPVTPISSSSSSSFQRSHTERSLRTLSSSSSTRPNMNLPASPAKTGSAIPTPYSNFPLLPPADLVSQEGVVSETVSEDVLASLQPFPGTSPTYGPSTPAFGPGAMPATPAPVGGTVSPTESLHRTNSMPAPMSLPTARPAPRRTATSGLLQQGLRPLRPPMLSFESFNPEYRLSAPMSAPDVRPATSSGFPVLELASAAQILEDNRPLTSAGLITIAPGAEPDTPPATVCSSSLASPIAIRGVPNRLTLTKQSPPVFDMFAHKGLPSPVGSEGPSPAPSEWSSVSSFSGDFDFTNLQASSMPNLPLPHTPLQLPTVPMSHYAAFSPTSTGSSTTSPVNTIPSQPFGSAFLFDDEMAFDQTLLPPLEEPAFGLPELPMTMSLPQETVDFENFMEDLTTPSASRADVPPDWSSAFANIVLQDEHLPHHASAFSSHDMADSHHHSMIPLEQASGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPD5</accession>
    <name>M5FPD5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623891.1">
        <property type="nucleotide sequence ID" value="XM_040769391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPD5"/>
    <dbReference type="GeneID" id="63684453"/>
    <dbReference type="HOGENOM" id="CLU_2605976_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="8986" checksum="05F4F7E77ED0436C" modified="2013-05-29" version="1">MDSLSWLIILLTALLISLLLWFALSSCLAHPIAHLSHSLWDTILAGAQAVEYAPSGRMRRAPREVFGEEWELERRGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPI2</accession>
    <name>M5FPI2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication protein A OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_25222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040774065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPI2"/>
    <dbReference type="STRING" id="1858805.M5FPI2"/>
    <dbReference type="GeneID" id="63689127"/>
    <dbReference type="HOGENOM" id="CLU_637820_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="127"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="3">
        <location>
            <begin position="255"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="390"/>
            <end position="430"/>
        </location>
    </feature>
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            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48193" checksum="6559BD26380779A7" modified="2013-05-29" version="1">MKVLTFEEEVIDGLLKNAAVGVVMRLESVRLQETQAKYLRNGLLPIEAVVDHNSRIEFPLQDHGIPSLSLELTKISLLRAMKVGTEVNVIGVVLHVGEVEAMSEKKRVAGKSGDGESESEEEDPKGERVRREVQLVDDSAHVVRVALWKGRATSMAVKRDSILLLKKVVIAAHGGISLNVYEKTKVDKDPKVAEGTSLKNCCNNLASNPQTFRHISSGYSAGSGLFTDIEPRSNVLTIPEVQKSNLGTGSRVDTFNVEGRIQVVDRNAVYEACRNTRCNKSIEKSPRDIEGHEDTSDDNRRFCYHLKLTIGQDRRRTIDVSVFTPLADKMLEEDATEVVKKRDHMPGQYDEVLGALLKTKWRFTIQARTQLWKNKWSGEWSRKLTYVVTGEEQLGEEEGEDEDEESREDVEGENGEDEVPEVFEEEGDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPJ2</accession>
    <name>M5FPJ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_118435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPJ2"/>
    <dbReference type="STRING" id="1858805.M5FPJ2"/>
    <dbReference type="GeneID" id="63685643"/>
    <dbReference type="HOGENOM" id="CLU_785321_0_0_1"/>
    <dbReference type="OMA" id="CITRELD"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF32">
        <property type="entry name" value="ARGININE METABOLISM REGULATION PROTEIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="353" mass="36548" checksum="C2B75927C8BB3475" modified="2013-05-29" version="1">MASSNANTTNNNNNNHGNPNTANNPPPQPPHLSAHYPFPPPGVGAYPPHPGWSFPPGTEGAFYPYPLPQPDPAQGGDPSNPLPPPLPPMPYGIPPFPHYFTPGAPGDYPPTTGAMRSPGGGSQRRASTGPYADGEEREPRKAAKKTDVACDFCRRRKLKCDGERPSCGQCITRELDCRYEIGPPRRRGPGKKNRALLSMSEEDREADRRAVASTNLADVASGATIHRSGAGAHAGSGAGAGAGAARTGPGKGRGGLEGPTPLYAYGPIGAFPPPPPGYAYPHVPGAAYGFTPGYPPPPPPGGRRYPPPVQSPEKTNGKKGGKKAQDAPAGGGGGGGGERERDQPNPAPEEQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPJ8</accession>
    <name>M5FPJ8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795924">
        <property type="protein sequence ID" value="EJT96479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623377.1">
        <property type="nucleotide sequence ID" value="XM_040774267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPJ8"/>
    <dbReference type="STRING" id="1858805.M5FPJ8"/>
    <dbReference type="GeneID" id="63689329"/>
    <dbReference type="HOGENOM" id="CLU_101432_0_0_1"/>
    <dbReference type="OrthoDB" id="444848at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="179" mass="20401" checksum="1A350D333165159B" modified="2013-05-29" version="1">MNTTGDPTRWNEFLDAALFATRVRQQTTAKWSPFELLYGRKPRLPFDQPLLRAPDAALPGDAEHSERHLQMQKAREQASERGHYPHGHLRPGLVNGNRLRLAHLREDDTNHRAWVLPNATQRQWSKEDKEAASQAVVRAMPSIRIIGRFANPNTGSAPVTVAEDESQNTQRTVMPRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPZ6</accession>
    <name>M5FPZ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623542.1">
        <property type="nucleotide sequence ID" value="XM_040774228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPZ6"/>
    <dbReference type="STRING" id="1858805.M5FPZ6"/>
    <dbReference type="GeneID" id="63689290"/>
    <dbReference type="HOGENOM" id="CLU_2005718_0_0_1"/>
    <dbReference type="OMA" id="TDQRYHE"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052567">
        <property type="entry name" value="OP_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202:SF1">
        <property type="entry name" value="HD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="131" mass="14821" checksum="8BE1E2C0A5A47331" modified="2013-05-29" version="1">MMTEHGSVGRQGHERLGATYLAELGFSQKVCELVGAHVIAKRYLTAIDKSYYESLSEASKISLRFQGGPFTSAEIEDFERDGHFRDKVALRGWDDQAKVVDLAVPELDAYRSMVLRHLRLQSSPMFAQDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQD0</accession>
    <name>M5FQD0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_119305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624541.1">
        <property type="nucleotide sequence ID" value="XM_040770761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQD0"/>
    <dbReference type="STRING" id="1858805.M5FQD0"/>
    <dbReference type="GeneID" id="63685823"/>
    <dbReference type="HOGENOM" id="CLU_014330_4_0_1"/>
    <dbReference type="OMA" id="LCGWVDR"/>
    <dbReference type="OrthoDB" id="439710at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001750">
        <property type="entry name" value="PRK00476.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="114"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="660" mass="75370" checksum="31CBAE1985BD6278" modified="2013-05-29" version="1">MSFIILRDYTGTIQLVYRSADLDMPHELDLAELPPESIISIEGTVQARPSKARKEGARGQVELIVRKFTLLNPAERPLAFYPTQTDNLPSAEFRNKYRYLELRREDLANNIRKRSRVTRVIRNVLDHQGFLDVETPVLLNSTPEGAREFLVPTRLHPLNQQGEAVPHESGDPPSPPTFYALAQSPQQAKQLLICSGAIEKYYQFARCFRDEDGRKDRQPEFTQLDMEMGFVSWAPREHDLVSGWRIGGVEVKDAIEMIIRRIWEEMEGVRLPETFRTITYQEAMTKYGSDKPDTRIPLEIVDLTTLMPMEYQEEIRTAKTEQCRAVDCLRIPRESPFATRDLRFLGKKPNSEIQRITISEDNLMSWLPDHPQVRFGNNTDLMRDLNNSLSLEVGDHLFLWWRDDYHSGGSTPLGSLRLALAEQAEKLGKYTPPKEPHFLWVTEFPLFTKDVEKADLVGGEWSSSHHPFTAPMPEDIDVLMMGESRHLKKVRGQHYDLVLNGMEIGGGSVRIHDAVLQEFIMEEILKLNKPTMARFNHLLQSLRSGAPPHAGIALGFDRLMSILCNTPSIREVIAFPKTAEGRDPLFGSPSPAREGVLGMYGIRAGKGRRQKHRDKLAHDVWAGEETAGLQSVEQSSLTLMREQWKLSEDWGKDKRENNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQD9</accession>
    <name>M5FQD9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FSH1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_85338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623817.1">
        <property type="nucleotide sequence ID" value="XM_040776730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQD9"/>
    <dbReference type="STRING" id="1858805.M5FQD9"/>
    <dbReference type="GeneID" id="63691792"/>
    <dbReference type="HOGENOM" id="CLU_051938_2_1_1"/>
    <dbReference type="OMA" id="EEPRGWW"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="28905" checksum="EBC24FAB669C0986" modified="2013-05-29" version="1">MIRLLALHGYTQNAYMFSKKLGAIRKACAKDIEFVFVDGPIVLQPADLPGANLSEFDSEGGAAQWVDDPKLTARAWWRANDEKTEYYGLEDSLRYLRDILEKERFHGILGFSQGACMAAYLAAYLEEPSAQPMFNPPPHPAFDFAIFISGFAPMCPPIEHHIRTKNVHILGRTDTLVSPKRSETLVDICIAPRVEYHEGSHYVPSKASWRHFFHQWMAAFSAESIRKPDDIPSPVPSAGDDTPSGAQTPASGTMTPRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQY5</accession>
    <name>M5FQY5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626328.1">
        <property type="nucleotide sequence ID" value="XM_040773484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQY5"/>
    <dbReference type="GeneID" id="63688546"/>
    <dbReference type="HOGENOM" id="CLU_2346643_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="97" mass="10599" checksum="951AE56329F77866" modified="2013-05-29" version="1">MCSVASANAGQADVASLRLLYRRTTRGRTIWLWMLRLLGVIQMIIGENMPRMIAGNPWEGPLSGRGSAGHLSRSCHLLDVEQHQQTGSDPSDTLGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR14</accession>
    <name>M5FR14_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626373.1">
        <property type="nucleotide sequence ID" value="XM_040770439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR14"/>
    <dbReference type="GeneID" id="63685501"/>
    <dbReference type="HOGENOM" id="CLU_583972_0_0_1"/>
    <dbReference type="OMA" id="YDASTEM"/>
    <dbReference type="OrthoDB" id="549336at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="52741" checksum="6ACDD233154D5D09" modified="2013-05-29" version="1">MQRGSLPPKQRGYLAVCCIVIIICILWFYRNQVLLEATASYRTSLTSTPTSLNHTSLSSLRVAVVEQEEFHNEVLGAVLSDLLRLGVRPQVYRSVPYLYRFGDVLQRFYPYGFDQSIVKNEDTGVFQPGPVEDAIRAGEYDLVILNSCHWAIWWETNIFMALNSSDAHVICILHTPHEEGIGKARFQYSALGAQGRFTGLSLSTHTQDAAMKLFDKWADKEHDRSWDKIPVEYFVPIFPAISDPQAIHKSRIPSKFVIQGSIDTLRRNYDGLIAELLQIMKADLHSWGYYQEKEGSPFLPLKKPAHGAIPPPFNLHLIGHSIREPKIPDEMVNVVHIRDSPDFEEFYGTLAEMDVLIPAFSADLYLTAVASSSIPAAVMTRTPILASPAHLRAYGYLAPPAVIVRPSSMSDAEAISRLRAGLPLLEDTAIQGNRFDLPEYRDWDAYTESLLQSNTVTWRRILARAIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR89</accession>
    <name>M5FR89_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_55383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EJT99605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775321.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
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        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="106" mass="12195" checksum="F90D7383F33F2707" modified="2013-05-29" version="1" fragment="single">YIFDLDAEEKREDLSLEGKFSVDAENCGNWTRFINNSCEPNLFVRTVNYEAPAKYHPGRLMFICLRDIEAGEELTFTYTPTHAVAPEDIPSKPRCYCGAESCRGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRP6</accession>
    <name>M5FRP6_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRP6"/>
    <dbReference type="GeneID" id="63688754"/>
    <dbReference type="HOGENOM" id="CLU_2359688_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="96" mass="10507" checksum="F86A842D8E92E47E" modified="2013-05-29" version="1">MTLTSGNVWSASVSTGVPPLFPFTRDIACACQGDRDRGCYGWAAEMLFSRYCSMTILGTGAYDAVPSVILWRNESCQLICDIPAPHRGVKRSRTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRT3</accession>
    <name>M5FRT3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E set domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_25081</name>
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    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624642.1">
        <property type="nucleotide sequence ID" value="XM_040773999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRT3"/>
    <dbReference type="STRING" id="1858805.M5FRT3"/>
    <dbReference type="GeneID" id="63689061"/>
    <dbReference type="HOGENOM" id="CLU_076228_1_0_1"/>
    <dbReference type="OMA" id="YKPTAAK"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="21488" checksum="7C0CECDE4EE59273" modified="2013-05-29" version="1">MSAQGNHEDAELQPTFAEGYKPTAAKSLDAYRELDKEDESLARWKASLGIGANAPAEASGPKVTVISLTLTSDSLFRPIVLHLSDKENFKKNPITIKEGAEYSVTVEFKVNHGLTTGLRFIQVVKRAGLTVDRLDAMIGSYTAGEAPYRKQMHTESAPSGLIARSGSYTARSRVTDDDKEVYADFEWVFKLGKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSA1</accession>
    <name>M5FSA1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624942.1">
        <property type="nucleotide sequence ID" value="XM_040770664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSA1"/>
    <dbReference type="STRING" id="1858805.M5FSA1"/>
    <dbReference type="GeneID" id="63685726"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="OMA" id="PEACHAH"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="145"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="24669" checksum="169AF715C2F365AD" modified="2013-05-29" version="1">MSMPTRRIANTDVSTIGFGAMGIGGVTFGPTGMTLDERPAVLDRAYDLGCAFWDTANVYGDSEILIGEWFKQNPEKGRNIFLATKFGFVVDEHGVTLDLSPKAARECCDKSLKNLGVDYIDLVDPKVPIEITVGAMADLAKEAYNVYPIAAVQLEYAPITLDMENPQVGILSTCRELGIAVVPWSPLAKGVLIGQYKSPNEFPEGDLRRFTPRFSAENFTKLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSD7</accession>
    <name>M5FSD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MFS monosaccharide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_95607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627223.1">
        <property type="nucleotide sequence ID" value="XM_040777307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSD7"/>
    <dbReference type="GeneID" id="63692369"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="QIEYEME"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="436"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="466" mass="50656" checksum="D3348F85B31FA584" modified="2013-05-29" version="1">MKNPNPALVGAVPGVYIAGEAAGALFQVFVSDWLGRKRFMMVLCVIVTVGSALQTGAPNFAAFLVGRVIAGFAVGGLIACVVLFNTASSEISPPHARGLVTGISGIGISLGTMVSNWIGLGGAYAPYGQIQWRLPLGLQIPWGIFLFLALLFVLPESPRWLYRHGHEEEARKAFISIHGGSFGSDREAEAEFILMTKVIEAERSQEVDSVREIFARYPKRTIISMASQTMTSLTGVNVIQYYQTILYKALGMTGNNILLLAGVYGTVALIANVLTTWFICDRFGRRPMLLLGLLSVVIVDAYNAIMTDVFATSSNNVAKGFAILGIYLFVTCYYGLLNSTTWLYAPEIVPLPIRSKVTALGAFTHFVVNVGLTEAGPSAFQNIGANYYWVFVGSSAFFLVFGWFYFKETKDLTLEQIAKQFGDDLVPVTEEDIRKLETEENKGDASSAGGSAEKQQAEIEHVENGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSE1</accession>
    <name>M5FSE1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Barwin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24322</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625651.1">
        <property type="nucleotide sequence ID" value="XM_040773642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSE1"/>
    <dbReference type="STRING" id="1858805.M5FSE1"/>
    <dbReference type="GeneID" id="63688704"/>
    <dbReference type="HOGENOM" id="CLU_047639_6_0_1"/>
    <dbReference type="OMA" id="NTNAYTH"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001153">
        <property type="entry name" value="Barwin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00967">
        <property type="entry name" value="Barwin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067187" description="Barwin domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Barwin" evidence="4">
        <location>
            <begin position="67"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="15501" checksum="9795AF1E9675E8BF" modified="2013-05-29" version="1">MYSLLAVTLALALSFFHFAHAYPVYTTEVVDPNTAISGRATWFYVGLGACGYTDTDLDWIVALNEPQYTGSACNRFLVVENTQSGATAVAKVRDMCPGCAEGSLDMSPDLFKAISTEGLGEGTGCRRPTNPPGTRPEGSASAHDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSG3</accession>
    <name>M5FSG3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625017.1">
        <property type="nucleotide sequence ID" value="XM_040771341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSG3"/>
    <dbReference type="STRING" id="1858805.M5FSG3"/>
    <dbReference type="GeneID" id="63686403"/>
    <dbReference type="HOGENOM" id="CLU_1749576_0_0_1"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="16647" checksum="39CEE7D6F9FA2CC4" modified="2013-05-29" version="1">MTAFGPTTSRRDLPQVGGGILGPRNALETPAHNKNPRFLRVPHALEHDPQHSLTALMKYRMKNASPQRQEQARLEVENAEDDLVQQTEVAITLRKTLLDNPEPLKNLNELVKAQLVFHSTAAEALQGIQGDIEELTVAAEGKYRKSRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT69</accession>
    <name>M5FT69_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_100799</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-(phosphooxy)-L-threonine + 2-oxoglutarate = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627688.1">
        <property type="nucleotide sequence ID" value="XM_040767492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT69"/>
    <dbReference type="STRING" id="1858805.M5FT69"/>
    <dbReference type="GeneID" id="63682554"/>
    <dbReference type="HOGENOM" id="CLU_034866_0_0_1"/>
    <dbReference type="OMA" id="AFVYFCD"/>
    <dbReference type="OrthoDB" id="1703350at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000010">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000006">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="9"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="406" mass="44855" checksum="B79CA001E35BFAC1" modified="2013-05-29" version="1">MSLERTQVINFNSGPCALPTSVLEEAAKGLLNYKGTGIGLAELSHRSGYFGQIVNELAGLIRKQLEVPSTHEIIFTQGGATGQFSAVVLNLLARHRLLHPNLAEEERYMDYVVTGNWSKKASEEARRLGGGVVNIVTDARTVSEDHKTFASIPPHSGFKFSQNPAFIYYCENETVDGVQFSTDPESPARFPWELLKEQDFVPVVGDYSSSFLSRPIPNLDRHALVYAGAQKNLGPAGLTVLIVRKDCLVDTDAAAKLGAQPVPITMDWKVIQSHNSLYNTPPMFSMYIAQLMLEHTEAMGGMPAITHMNEKKKDMLYEVLDEGAAKGLFRLRVEKGSRSWMNQTFHVLGDGKEKLFLEQAESAGLKALAGHRQVGGVRISLYNAINEEQTGILVKFIRKFIEENSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTP7</accession>
    <name>M5FTP7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linoleate diol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LDO1</name>
        <name evidence="6" type="ORF">DACRYDRAFT_100565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627923.1">
        <property type="nucleotide sequence ID" value="XM_040767466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTP7"/>
    <dbReference type="STRING" id="1858805.M5FTP7"/>
    <dbReference type="GeneID" id="63682528"/>
    <dbReference type="HOGENOM" id="CLU_002329_0_0_1"/>
    <dbReference type="OMA" id="EFNMIYR"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1034" mass="113620" checksum="CFEF54A7936740B6" modified="2013-05-29" version="1">MFGILNALSRASNSISASLAPVDTEGGSLKPPPGILAKTITEIEGLVKTSTAIGPSDVPAILDAVQNLNGPGIDDRLFLLEKLLTLMARMPADSAINQRIQSFFIDTLYKDLPHPPSAYLAPFPQITPDPYPKRSYHYRSTNGDNYSPAFPLLGRAGLPYSRSVPSASQVPPSSLPDPGLVFDLLLARPAGKFNAHPGGLSSLFFGMANLVIHSIFDTNRTDWNINDTSSYIDLSPLYGNGVSKMKAPPEALRRFDGTGRLHEDVFGDARLLFMPPTTAVLLVLLCRNHNYIAEKILSINENGNFQNPPPQDEVAKRAQDDEIFERTRLVNCGFFARVVLYDYVGGILGMTRDGSSFRLNLDEQIRRSDHEIAPVGQGNQISAEFNILYRWHASTSAPDEQWLDYTFKNLLQGKPFNEVTVDDFTKAATQAMRPNDPDPKKWEFGGLKRDPVTLRFDDAALAQILKDATEAPAHAFGARQIPQALRVVEMMTILQGRTWGVCTLNEFRSFFGLKPYTNFQEWNPDPAIYKAAEALYGNIDRLELHVGLQAEESKAPMPGAGLCPSYTISRAILADAVVLCRADPYLSTEFTPYNCTAWGYQDCILNPNDGSYGGALTKLMLRNLPGQYKTDDAYVHFPFLVPKDVRKNMELRKDPAVNKYDWKKPLTPSVVPPGTGIKTLKLIALSAQSQRIMNLVGKVKINRALINQQLSAYLSRPKTDDVFAEITKSLIDDKSVVQPGFNSKQVDIVQAVINLVPVHFVANHILGLPLKTTANPNGVCRPEELCAMFANAADYVLYDQDAPDEWYMREQAVGCANTVRREVSANLERLAHGLWSITGLVDTITDIICFKTNHSDVFLSTLLAAGKKEGMTIPEITASLLAVIIPSVPQFSAVVTQLVDFWLSKDQASKKTDLAQMAAAGPGMNPQIATYAKAAINSIPTLTPADAGAINGSVSASSPLNCVEGLMSEKTFDRLAPLILRSIFGLHNIRRAPGQSGVLPMFTQTILDQPQTFFINNESGLSPWPTRLMIQYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU49</accession>
    <name>M5FU49_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_110346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625917.1">
        <property type="nucleotide sequence ID" value="XM_040769041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU49"/>
    <dbReference type="GeneID" id="63684103"/>
    <dbReference type="HOGENOM" id="CLU_2158271_0_0_1"/>
    <dbReference type="OrthoDB" id="10321635at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40624:SF1">
        <property type="entry name" value="BIOSYNTHESIS MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12025)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="2">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12782" checksum="A19B734789E462E5" modified="2013-05-29" version="1">MISDPRVVVTAKFTIKPSKREAFELAWKEFADLVRKLEPKCLVWNVAVSEDGLTYWMYEEYMSQMALEEHEHTPHSKKFSSIAQEGEFFASVGRSSSGETPEINKGSRPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUL2</accession>
    <name>M5FUL2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623839.1">
        <property type="nucleotide sequence ID" value="XM_040770856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUL2"/>
    <dbReference type="GeneID" id="63685918"/>
    <dbReference type="HOGENOM" id="CLU_431482_0_0_1"/>
    <dbReference type="OrthoDB" id="3363223at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="634" mass="70235" checksum="8F5E0011108D33DA" modified="2013-05-29" version="1">MSDYELMASEPDQAASPPSSPFSFVSSIHPVDSPSDLSLAESILADDQETVDVRSVSGSEYDWSFVHQGSGADHAHHSSAFASNVTDSVCSIRSPSRTPSPQLKQPSFVVEPSPLPTPRERSPQVLQIPVLDASAQPLTLVRLLNLPPYYTLEDLVNLLTKRTPTICDTFRYIGRVPLPLWISFRPPNAQVEAVQTKAKAPEVPTSSALLRFMNPEDAAGLSDILEYMKNRLAMMDGGEFWFWLLDVDTILLSDEEAEKGEEDKGLLWVADWLRSDTISDMQTKNTAKKAASESITSILLTPLPYEVCLSDLVNLFTTNAAESAPRPRRISLLPDLAVHTIFLPCCILQFPDHVTANQAMTFWSRYDTLFFEVLLGGAPCSLEAACMSSGTRRCPLEWKLGDWWFYSGFVRNAQIWEHPSLATKDAFRAKEDVSGLLEEFPSHVARRRRLGAMGLQSSPHCQVSTKQSALLTALPPDVDLDEIVKVYTTPPVLSSSSLTSSAIEDSFKSAESMHTDVPNRQEDSVRPQDSSQSTRTIPLPSFISILYSHPKICPGSRMAVISFASAADFAEATCLLPPSMWFHPGTWAHPRGSFVKPEERDGTEQLYQCSYVYGDYSWLHHSSLGRRTTWVAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV52</accession>
    <name>M5FV52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_55663</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626372.1">
        <property type="nucleotide sequence ID" value="XM_040775342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV52"/>
    <dbReference type="STRING" id="1858805.M5FV52"/>
    <dbReference type="GeneID" id="63690404"/>
    <dbReference type="HOGENOM" id="CLU_033167_0_0_1"/>
    <dbReference type="OMA" id="DKQEWED"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="9">
        <location>
            <begin position="319"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="492" mass="55546" checksum="D655599E95D04A47" modified="2013-05-29" version="1">MTTVEFSGIVDLPPPAQPEAPSIPISEPIITGNHRFFPPPPPRTIVKSSLPQFSSGWTVFQNLYFSNGTFFIVKDQDQGGFGEGYWPERRLITSTGLPGLAGNEAEREPGLKEMEVIDIEEAKRIWEDRVFDVGGFSVLVNDPTQFLRHYYHVAAELFFATERVITNFDPMPAPDGTINAPNPNRMIFIHCDEEGFSDGPGLDHFFLAAQFPSMTPLFQPSWERMAQQVEASRRVFRFPGALFVDRSAAFRGGPTGSTSRTPASPWQAGGGSFGTGGLGRNQFWYESARRRVLSFAGVSKDILDIGLRAMDPPLATGKPDRPVITYISRQRTSRKLREEDHESLVDALQEMCLRHNWEFQLMVGETMPRDEQLLWAARTTVMVGVHGNGLTHQLMMPPHPRSAILEMYRPPNFAKDYEWTAGVLGHAYYTIHNDTFWTPPKLADINYDDWNTDKVKSIPVYAPNVVEIIEQQLLGENQGPKHWQSWREDVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV96</accession>
    <name>M5FV96_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626437.1">
        <property type="nucleotide sequence ID" value="XM_040777332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV96"/>
    <dbReference type="STRING" id="1858805.M5FV96"/>
    <dbReference type="GeneID" id="63692394"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OMA" id="KYWSQQY"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="317" mass="34639" checksum="E742471997E89408" modified="2013-05-29" version="1">MKLTVSLFLREQCTVLTKPASYAPSLAGKTVIITGANTGLGYEAAQHLARLCPGRLILACRDPKKGRDAAETIGRVTGCGNVQAWTVDIGSNASVKAFAERFERETEGRLDILIENAGVNVPKMERTVDGWEKNIGINHLGTAHLALRMLPFLLQASQPRLVILASDVHYFTADPEGLNQPDVLHRLNSDRQTNKFESFDGIQRYDVSKTLNVLWGEELSRHIPSSSSLTVTTLNPGLCVSALLRDHSFTHRLCARVIGRSTGVGSRTIVHAAVAPELQGKTGVFLSSCRITEPSDFVISKEGHAHCDPVSQFIRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVJ3</accession>
    <name>M5FVJ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_107571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628733.1">
        <property type="nucleotide sequence ID" value="XM_040768504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVJ3"/>
    <dbReference type="GeneID" id="63683566"/>
    <dbReference type="HOGENOM" id="CLU_434132_0_0_1"/>
    <dbReference type="OrthoDB" id="10638394at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="161"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="163"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="630" mass="69747" checksum="E516FA01AB3CC6C2" modified="2013-05-29" version="1">MELTNECDKLSNQDELQLLKRAYMINKCPSGLEIRHLALIMGRSHATVRTWFEAHKPVDTHDSVNRELQNALERFDYLDSSEQEDQAEDEESDLTESEEELVTPKNDPLSLQKSKTSNTSKTFYHDRQNHVSASHGSSTMPSTPAMGARSQESSSPTPRPGRTSSSRSLINGEKKAALESHFRKDPNPTMESRKKLALKIHIDPHRISQWFAMRRFRLRRASEESSKSNEYLDEKIISCVDVKPEEVPRPTPTLHRKPDPPAVTRAPINMSLRSKTRREPFSSSSTEPPPPKRIRFIAPASVKSRSSRARHAPRNFFPQPDWNAPPSSNKIPHFTFWFAKDRQASFLPTVADENLVACPDAQSTVSTLSPFVDQSRVSHMSKASSDLCANPKPRNPEFVAKPAANQSSSSKPGILRTTDFLPSITIQTETQSSISQVFQTNSASTLLPRSTSHALSVTSPQNIPGTKPVSRSIHSSISQDPFAENPPSLPMIGTMQGVSHPGSLIAYPASTISKADPRYGFHPPENQSSVHAHHNPTRHHHHYHVLPPRCAGTPTIPHSIGRWSYPMHLASSHTLFASASGSIPTNPHLAPPSKATVYSSHALDANVVTSTMSKLDTIATIAQMQAQAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVJ4</accession>
    <name>M5FVJ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_97184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624254.1">
        <property type="nucleotide sequence ID" value="XM_040777431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVJ4"/>
    <dbReference type="STRING" id="1858805.M5FVJ4"/>
    <dbReference type="GeneID" id="63692493"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="304" mass="33302" checksum="FD176F44F996A2A9" modified="2013-05-29" version="1">MSIPPLPPNTTLQGRSFLITGANVGLGFAAARLALQLGASPVYITTRTAKKGDKARDELLADPEVKKKNPNAIVKVYEVEMSKWDSVTSFAKKFLDDRKTAGEGLDIAILNAGLVNGRFVLAPTGNEMDVQVNHLSTAPLALLLLPLLERSTTPEHTARLTIISSMAHLRARLTPQDDIGYLPSLNDKKSFSPVLQYSLSKLLIILFLRELCEKVTSDKVIIWSRQSGLAICTARSSPEKGAITYIDAVANIGKESHGLWYQKTRLTPYSKVVTGPEGKKLQKRSWDETLKQLEQVSPGVDPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWK1</accession>
    <name>M5FWK1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl-CoA synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626962.1">
        <property type="nucleotide sequence ID" value="XM_040768888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWK1"/>
    <dbReference type="STRING" id="1858805.M5FWK1"/>
    <dbReference type="GeneID" id="63683950"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF295">
        <property type="entry name" value="ACETYL-COA SYNTHETASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="286"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="633" mass="69751" checksum="54AB2D0B91405ADF" modified="2013-05-29" version="1">MSQVALEPIYPPANADYIPTDNLFAYLFHNQQVWRRIPPSDDRVVFHEPITSQDLTYGRLRDDSLRFVHSLSKLVVNVPPKDDFGVPGAIVGPVVMIHLPNCCAFPVIFLGGVATNCTMNLVSPALGPNELVHVMELVHPDVVFTQPGELGEETLEKAFNLLPGSPIKPKIFTVDVLQYPSNCSPSDLPANNWLTLLNTSASSQVAPMVSPGFPTSTMKLTRKHRMLMSNPIALHVFCGPQAPPAKARGLCILIGLLSLPMCCGKSMLITKETMLYVLVLNLASLIGTESGQVWIGLPPFYHIMGLQTVMLLAVQYSTKVVIMRKFDLEAYLRNIVRHRVTYLNLAPPLALALTKTPLLDEPWCDISSVRSAGCGAAPLGADIIREFHRRTGKLILMGYGLSETGCFTHRPDPSWQTVEKSLGFSGRVMPDVEIQIRDEAGNPVPNGKPGEIMMRSNLQMLGYVRNPKANAETFAKDGFVHTGDIGILTDDRFIKIVDRIKDVIKYNGFQVSPVELDAVIGALPSVLDVGTTSIYSEQQASELPIAYVVPRSLELLAAVKRGDKNHPGLKPFAKEVYNTVESQCAYYKWLRGGVVLCEAITKSLTGKIMRRQLKDISGIHVPFKNRPDVRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWM5</accession>
    <name>M5FWM5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metallo-hydrolase/oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_95496</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627686.1">
        <property type="nucleotide sequence ID" value="XM_040777301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWM5"/>
    <dbReference type="STRING" id="1858805.M5FWM5"/>
    <dbReference type="GeneID" id="63692363"/>
    <dbReference type="HOGENOM" id="CLU_030571_1_1_1"/>
    <dbReference type="OMA" id="GDCCHDP"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="44"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="36245" checksum="9C17372A0669D7E5" modified="2013-05-29" version="1">MSIDAVIAALPFSPIPEGESYCEVTPLAQIITPSSSATALYRAPTFSFYVKHEPSGKTLFFDLGIRYDWETGFAEDLRNFIKPAPPVMVGDVGALLKEGGANPEDVSGVIISHRHWDHTGNIAPFPKAEVVGGIDTFNADLGRQTAGRQTLVLDWSRVKSSKIGSFDHAYDYFGDGSIWLCDSAGHTAGHLSALVRTTPSPNATYVLLSGDTCHHPFLISPTTHNFRLATYPARGGSDNPRKHPGLPPPCCMHSDMERAWDTVCRTRRMEAEDNVMVVLGHDYVYWREWRDNLNRLWPNKAGIHGWKKDGLKMERKYEPEKYDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWP7</accession>
    <name>M5FWP7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627007.1">
        <property type="nucleotide sequence ID" value="XM_040770434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWP7"/>
    <dbReference type="GeneID" id="63685496"/>
    <dbReference type="HOGENOM" id="CLU_653859_0_0_1"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20273">
        <property type="entry name" value="Complex1_LYR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046896">
        <property type="entry name" value="Cup1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="37"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="420" mass="47876" checksum="638A329720256359" modified="2013-05-29" version="1">MSTPYHIQLIKNRLIRIGAIDKPKPTSIEITRLQRIQTLALFRSALRETKKIKHDTHLRDWFLEWFRSSFKKNKQVASDELLRTKLKRGARELRCIRNLNAGSITDLDRALKYAYARVGPSRHEIMQRILSQPSPPARHLIKNDPRGSLPRYPALLRHLLTNQSINTESPVDMSKLVRPPTLPDRADPTSEDAHLLGPLPQRREKNIHWRYYNTLLKDIRMPLGSVGGPYDVAGLGTDTFSRLERLAKGHGDDGSKLGRAMKRAYRRILGITPHTKYIDDPKGPPDRDEDRLEHPEVHDGENGTEDGKQSATLSARNYVTRISPLAVQRIGRFNGPSNPHTMPVAAEKWVQRALQADFEEQQHLRETARKRVIRKKMSERAWFGGDELRQLGALMAPEIEPEAETGPDARAQSPSSVSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWU4</accession>
    <name>M5FWU4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_88793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629335.1">
        <property type="nucleotide sequence ID" value="XM_040776877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWU4"/>
    <dbReference type="STRING" id="1858805.M5FWU4"/>
    <dbReference type="GeneID" id="63691939"/>
    <dbReference type="HOGENOM" id="CLU_144328_0_0_1"/>
    <dbReference type="OMA" id="HVTCSTI"/>
    <dbReference type="OrthoDB" id="2550823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="167" mass="17803" checksum="9FBA998F3F8DE807" modified="2013-05-29" version="1">MHHLSNTPPTSCNIGMLSPEAHGSQTGSSSVFLLHVALELPFALQSLLMAEHLPFLEMTNTTLVVLKIYGALAIGTCVGAVLCRSLPEFLPGKRAMALSLLVYHAIAAATLMTSPRFVPLSFGPLAESLTITPERSYAVLHGLAALGFASWWQVTLPYVAAAKGKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX14</accession>
    <name>M5FX14_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_37335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627142.1">
        <property type="nucleotide sequence ID" value="XM_040774429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX14"/>
    <dbReference type="GeneID" id="63689491"/>
    <dbReference type="HOGENOM" id="CLU_2855832_0_0_1"/>
    <dbReference type="OrthoDB" id="3040543at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="65" mass="7912" checksum="EECB8D3BBD87CD5A" modified="2013-05-29" version="1" fragment="single">ADKYIVTFKELAFQTKYNSIALIKQFQQGLHQSLLDKIYALPEMPKKLKDWYKYALRFDQQWQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX38</accession>
    <name>M5FX38_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624934.1">
        <property type="nucleotide sequence ID" value="XM_040769161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX38"/>
    <dbReference type="STRING" id="1858805.M5FX38"/>
    <dbReference type="GeneID" id="63684223"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="SHEYLIL"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="315" mass="34209" checksum="6756E76D850E4334" modified="2013-05-29" version="1">MADVPDLSGRVALVTGANRGLGYAVAVILAQKGAKVYIACRSLDKAVQAVQQMEIAHEALKGRLIPLEVDLGSVRKSKAAGEEVIRLEGIMGRLDILICNAAQTGTPYEENEEGISTIMASNHLGHCALTLALLPLLDRTDLSPPCDVRVILVTSAGYALAPKPWQFKSVRDFRNDAGQKEGGLVTQLARYGQTKLANILFAAELQRRFKRHHTQSLALSVHPGGVVTSGAKNFLRTWYWVFAWGFVPPEKAAKAIVFDAASPKVREQGWGGAYLVPGGKKGKLQKGAQDETLAKDLWELSERVCKEIEEKGKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXL1</accession>
    <name>M5FXL1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_53973</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627427.1">
        <property type="nucleotide sequence ID" value="XM_040775219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXL1"/>
    <dbReference type="STRING" id="1858805.M5FXL1"/>
    <dbReference type="GeneID" id="63690281"/>
    <dbReference type="HOGENOM" id="CLU_074404_2_0_1"/>
    <dbReference type="OMA" id="WHPEHFE"/>
    <dbReference type="OrthoDB" id="412109at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="114" mass="12574" checksum="BF863A87B7BDE1EB" modified="2013-05-29" version="1">MALLSPASPGSPGTVGLGFTDLPWPCYPAPLSPEDLKPLPIQRFILSPSHSASQGAKERVRQALLRWHPDKFEGRWMGRCSEGERGEVRQGVRAVVDALGEVQEEMNRRGVWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXL8</accession>
    <name>M5FXL8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629660.1">
        <property type="nucleotide sequence ID" value="XM_040772525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXL8"/>
    <dbReference type="GeneID" id="63687587"/>
    <dbReference type="HOGENOM" id="CLU_1219662_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="227" mass="24853" checksum="BDCE7D9ECC9FC69D" modified="2013-05-29" version="1">MDGRNEVSASSDVLQEGGVRLYPAFETPRLRRGTSSRVFPSTSTKDQGKLKRESGVEKATRRRIVGQSISITRYQPLPHQTRTFSQTLLPAASFASCEVFSCASLRRLNTACGCQEGFDHMLRPGLGDGWSRSADGLVLYCGGLTWCYHILATADVLGASGEEGWAGDALIAVFERIYSSAWCTYVRKIWPLWSYGAGEIRVCVAVAVDDVIDLNFGARIHGGRACY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXM6</accession>
    <name>M5FXM6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_111228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625154.1">
        <property type="nucleotide sequence ID" value="XM_040769197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXM6"/>
    <dbReference type="STRING" id="1858805.M5FXM6"/>
    <dbReference type="GeneID" id="63684259"/>
    <dbReference type="HOGENOM" id="CLU_008721_4_3_1"/>
    <dbReference type="OMA" id="NWVEGLI"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="56969" checksum="5610152E761B51EB" modified="2013-05-29" version="1">MAPSEFKPDAPLPGPPRPPPKPPAHSYPNVSWRPPPRTYNEEASIAERAYAAQTPAQVPPPVHQSRTMTAARKTYPYPGGRYTTPREEIQYAYFAPGAQPPPVPEKETFGESTHAAEAWRRSQADMREEGPGSGLRYLVVRTWLNALLLFVPIAWLGHFLNWDFKVVFALSFVAIVPLQIVLDFLGAQMKLHWGKTLGGLMAVTIGNGAPASLAVILLLRCELRLLQSVVAGVLLLQLLVLPGVALLASQAGGAPARLNQSLISLAVLSLLVLVAFYAATFGIALPATTAQVTTTQAEILQISRGMAIILIVVYLGSRLILPWIVSEDVSYEAPEREIREIYEEEEPIVPPWLCIFLVAIFLGVLIVTVLWLVDSFPFVTTEPFTLEWFGLILLPFLTFGSDVLIGLCYLFQRAILPMTDPLPPRPSGLAMDLSIQFALFWLPLVVLIGWGLGKPMSLLFDLYEVAILIGVMYLTNNSSLDAWTTPAEGLLLVAGYVMIGLCTWFYVGQPAIATLLTCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXV4</accession>
    <name>M5FXV4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXV4"/>
    <dbReference type="GeneID" id="63688125"/>
    <dbReference type="HOGENOM" id="CLU_1686508_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="17869" checksum="C56CFD29156A6319" modified="2013-05-29" version="1">MSWFTKLSGEEGWGTRGGRIFVAVVGEEVKGKAGMIIGWCMATMAYPPHLPDTLLSQLYLSAIYVHASYVTQGVGRQLVQYLATEAGKGHAELIRAECKRLPKLVQMHESWGFTPVRYTGWAEDYEDKMQLFHMDLRTDEEREQDEYVEDEDEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY40</accession>
    <name>M5FY40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_106156</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629875.1">
        <property type="nucleotide sequence ID" value="XM_040768213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY40"/>
    <dbReference type="STRING" id="1858805.M5FY40"/>
    <dbReference type="GeneID" id="63683275"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="44"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="548" mass="58151" checksum="0A489FE2AF9BDA8E" modified="2013-05-29" version="1">MSYHLLPASPRESGDSDSSLDEDLPVKEDTNGPETLSTVQVRLILVQLYTIVIFYGMDSTIVATLATPISSAFGELHRAAWLNNAYLLTVACCAPLYGRLSDIIGRRKALGIGLAVFILGNALCGAAGNMNVLILARLLQGAGGGGAGLVATIVISDITPLRDRGLLKGVSAVCWASGQGLGGVFGGLIADAVGWRWAFLFQLPVLLSIFCGLMNMISYDLGYQRPADASLRRRLDWNGSVLFFIGIGSLVFSIAYKTNEDLSWSHPLVALTLLLSILASGLFVYIELQTDEPVLDLRLLGNPSLACIGGTSFLSSAATVSVGLYFPMLLQIVRGNSASSAGMHLVPNTISTACGGIVSGLYIRKTGRYYKLILFLAFLQLLACLSLASLNRTTWEPATWLVLLPLGFSTNGYNGSTFIALLNAVDAKDLAVVTSMAFMFRSCGQVLGMAFSSAVQQTTLSVSLAHRLPASIAPQIMAEVRKNAASILSLPPEPRDACISAYSTSLHVVFLTSAGLLVGAGALAALIREREIEGGRTEKGEDERGDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYF2</accession>
    <name>M5FYF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628451.1">
        <property type="nucleotide sequence ID" value="XM_040768588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYF2"/>
    <dbReference type="GeneID" id="63683650"/>
    <dbReference type="HOGENOM" id="CLU_1570600_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="18803" checksum="2ACAB41008372794" modified="2013-05-29" version="1">MADAVSVPIARGQTNTSKKSSNKGKGQSFSHMTLDEMKALSPAAVTALTGAELHAASKDLVQQVMQAWSTEVSEGVMHMLKQYKEDEAKCLQRRKEKEAKCTRYEPNSHLSLPLLCWRFDVNTVPIYNVFLGFFVFVFTLFSSSSAKSSTSASRYEREITALASILKAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYG6</accession>
    <name>M5FYG6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_118425</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625489.1">
        <property type="nucleotide sequence ID" value="XM_040770579.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FYG6"/>
    <dbReference type="GeneID" id="63685641"/>
    <dbReference type="HOGENOM" id="CLU_000604_27_1_1"/>
    <dbReference type="OMA" id="EACIFGY"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="294"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="978"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1021"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1124"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1158"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1206"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1239"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="307"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="682"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="980"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1299"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="400"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="913"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="400"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT98591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1551" mass="171528" checksum="22021EA086DE8035" modified="2013-05-29" version="1">MDSFLSQLQLQVGDSPMDTHVWFDLRLIPLYLCCVSLLLLFLTALAYLRSVKVRVERRLPYPTVYEPQLPGSSTGLADRVKAHVVARGGLGIYGMMGLKFVGCAALFCVTGAVVVREWGKGDEQWTEVGLGVAYAYSTVLSFLSLALGPVGRQHCRRHTTLLFLACFSIFGYRDLLPLLTFSGTPADPPWLLYTNGTLLTLTAVLLPLLTPRLYTPADPLHPTPPNPEQVASPLSVLFWSFLDPIFVAASLYPEKLAHLPPLADYDQASYLSRRAMPRLDPESRRAQGLKERHIIWGVAEIWASGFLAMALCLVLRVCTVLLGPVSINRLLGYVEDPGSAEVRPWVWILLLAGTPLLHSMCYQTYLFLTTRLLVQLESVLMQLLFKHSLRIQLFDEPSVSAPSSEAISGESTPSAEETTVGTQTDNSRSSPALIDKGKQRAQPVQGTKESSHLVGKINTLIGTDLGNVMGARDFLFVLLQAPLQLILSLWFLYAILGWAAVIGVAFMLLCIPVPGIVGRWIHTIQTERMKRTDARVQAISETLNVLRMVKMFGWEGRVKTQIAEKRGEELKYVNQALIVDVLHSNLNFVIPIVAMILTFAVYSLVLGYELTASKLFSSIVVFDNLRYQIFLCFSRIPSIVTGWVSLDRINEFLHKTELLDRYTSDSAAAVAIARGPPEPEVVGFHNATFTWHNIKPHVSTPGRRNFRLHLDDLVFKPNTINLIIGPTGSGKTSIFMALLGEMHFQPSGPDAWFHPPREKGIAYAAQESWVQNETIRDNIIFGEPFDEERYNSVIEQCALDHDLALFDAGDQTEVGEKGLTLSGGQKARVTLARAVYSRAKVLLLDDVLSALDVHTSKWIVDKCFRGPLVQGRTVLLVTHNVALAAPVAGNIISLDINGKVIGQGSIEQVLSHDAHLREDMEESLRELEKARKQEDLDRTEKRVKQADGKLVLAEETAVGHLSWKALYIFLSSFGQGGFWAFVFISVFFVEMAQNLATWWLGVWASAYVRQDAGGFVVNVPYYIGVYTAIVTGYVSLYITVSITFNYGTIRAARKIHDRLVHAMLGSTLRWLDSTPVGRIVSRFTQDMRQMDGPLAEISMRLIELTWTMVTKFAAVIYFSPVFTIPGIGVIVIGGCLGQIFSAAQLAIKRQMSNRRSPLYSHFGAAIAGLTSLRAYGAEHFFEAELLRRIDLYSQSARTFYNLDGWISIRVVLLGSLFSAALASYLVYQKVYVGAGNIGFSLNMSAGMVGMTFSWILNLNQFDVAANSLERIVDYLVIEQEPVSTEKGKPPAYWPSSGSMKVENLCARYSKDGPTVLDKLSFEIRSGERIGIVGRTGSGKSSLALSLLRMIPTTGVVYYDGIPTNEINLEELRANITIIPQDPALMSGSLRSNLDPFSQCDDHVLNDALRAAGLFSLRTENPEDAITLDSIVTSRGGNFSVGQRQIIAMARAIVRGTKVLILDEATAAVDAATDGVIQASIRSELKHVTRLTIAHRLQTIADYDRIMVLDAGKVVEFDTPTRLLEIDGGVFRSLVEESVDKQLWGMARKSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYI4</accession>
    <name>M5FYI4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625504.1">
        <property type="nucleotide sequence ID" value="XM_040773598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYI4"/>
    <dbReference type="STRING" id="1858805.M5FYI4"/>
    <dbReference type="GeneID" id="63688660"/>
    <dbReference type="HOGENOM" id="CLU_028458_2_1_1"/>
    <dbReference type="OMA" id="YMHYECE"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="76"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="289" mass="31197" checksum="AE808E5FEBAB24CB" modified="2013-05-29" version="1">MTWSRLLRFLPPNSTTPLLGEPVNEAQDVGLATLNGEEVKVAVFSGSSVLSPGEKTGRVEVVERLLSPLAMEEVGTIRCIGLNYIKHAQEAGMPLPKVPVLFLKPSTALSDPYPSPTPIPRPFVKDDAADYESELCVVIGQKCRDVSEQEAMGYVLGYTASNDVSSRVAQLEQSQWCYGKGQDGACPIGPTIVSTNAIPDYTQLHMRGLLNNTLVQSTKLDDLIFSIPQIIAFLSKGTTLLPGTLILTGTPAGIGWAMNPKGTLKDGDEFKVEILPLVGTLVNRIEFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYN3</accession>
    <name>M5FYN3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628521.1">
        <property type="nucleotide sequence ID" value="XM_040768599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYN3"/>
    <dbReference type="GeneID" id="63683661"/>
    <dbReference type="HOGENOM" id="CLU_2196860_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11381" checksum="DAB9353A0AB57C22" modified="2013-05-29" version="1">MGRNTGRVYQIVAAATATATATTVAAAAAPAARAKAQPAAKTLATLRGGKKTAMQQENRTSDKRGGEMAQEEGNGERESCIKQESRELEEVELLESQFTAGDAREQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYP7</accession>
    <name>M5FYP7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628536.1">
        <property type="nucleotide sequence ID" value="XM_040771181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYP7"/>
    <dbReference type="GeneID" id="63686243"/>
    <dbReference type="HOGENOM" id="CLU_029462_0_0_1"/>
    <dbReference type="OrthoDB" id="3419411at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="631" mass="69494" checksum="B317423D81D25662" modified="2013-05-29" version="1">MGNKKNQIAHLSWAQHKEAASAVQWTEETEGLKTRLSRPVQLKQVADGELMTKMNEQSQPKPQPLTRCSKVKEMVVDMAGLPVGETGDDPCMLAQLTQSTNVDICATTNAVTAQSYTLPSDLVTPGWNNSTTWSKVASSTPITNTTNQPVDFNNTSLILLSGVDNLQALIKDLHKQGVVTCDQVENSITSEPTSLVLATDPLPEKYHTLKQKARQSESSKSSHDDLTQEMFNETRDSAYLEGIENEAEEEEEEEEEEDKSGKSALGSAAQIFQLPADKGFKALQNAVGKLLDLFPNMLSLAYILSTSHVKEIPVLLESASTFIKMVQQWWCSTHKEETKAEQTYTCLEGTWKKQCHRAAELGAKAPNKPKRPAPITVYIILSNTSSIAQDDKSKDKVKGKGKGKVLLLAFHTYLPLTASLWNQKKSNSPCASLEEQGKGLSRKVPNVTEIEPPGNIMDKWITMSGSCQSEGPLCQATCPSKCQAVEQAVASPGSQQFYSHIPMQPLSPPWAGPMWAPPSGFQPFAFPMEPTGIEDGIDILIPSPLLRQWLEKSMDGNPQQNSDQHNFSQYLDAFIKAGLYCLGELVAVGSVDKLLDTYHSSEPKERMLHGTAVVLLNYARVDFKQLHHQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYW4</accession>
    <name>M5FYW4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial Rho GTPase</fullName>
            <ecNumber evidence="15">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_24327</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Mitochondrion outer membrane</location>
            <topology evidence="2 15">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the mitochondrial Rho GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="15"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625659.1">
        <property type="nucleotide sequence ID" value="XM_040773644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYW4"/>
    <dbReference type="STRING" id="1858805.M5FYW4"/>
    <dbReference type="GeneID" id="63688706"/>
    <dbReference type="HOGENOM" id="CLU_014255_3_0_1"/>
    <dbReference type="OMA" id="HETTWGI"/>
    <dbReference type="OrthoDB" id="10020961at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01893">
        <property type="entry name" value="Miro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01892">
        <property type="entry name" value="Miro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000011">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000553">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001330">
        <property type="entry name" value="Mitochondrial Rho GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013566">
        <property type="entry name" value="EF_hand_assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013567">
        <property type="entry name" value="EF_hand_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021181">
        <property type="entry name" value="Miro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052266">
        <property type="entry name" value="Miro-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020860">
        <property type="entry name" value="MIRO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08355">
        <property type="entry name" value="EF_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08356">
        <property type="entry name" value="EF_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037488">
        <property type="entry name" value="Mt_Rho_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51423">
        <property type="entry name" value="MIRO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 15" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="19">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="186"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="306"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="19">
        <location>
            <begin position="431"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="399"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJT98761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="659" mass="73601" checksum="EB08E8C95DE229F5" modified="2013-05-29" version="1">MRRDVRILLVGDDGVGKSTIVTSFIKDYYVPHVQAVVPEVTIPPEVTPENVTTYIVDSSARSQDRQRLDSELRKAHVICVVYAIDNPHSFDRVPTYWLPYIRSVGVNVPIILVGNKIDLRGGEVTNEALEDEIFPIMSEFKEVETCVECSAKLPLNVSEVFYFAQKAVLHPTAPLYDSREHVLKPACIDALKRIFKLCDVNKDGILDAQELDEFQIKCFSQPLQAQERTGIFEMVAQGIPDGIRDEGITEAGFLYLHTLFIQRGRLETTWTILRQFGYGADLKLTELFLSPKFDVPSDCSVELSPSGYRFLTDIFEMHDKDQDGALRPEELDSLFSTSPGCPWTKDGFPETTFTNDRGWVTLQGWLAQWSMTTLLDHKTTLAYLAHLGYPLPSTIIPSSSPSTATTSVSTTTALQVTRPRRSDRKARKTSRNVFLAYVLGAGGSGKSSLLRNFVDKPFTTEYQPTRSLLSVVNAVEVGGRERYLVLQEFGSKYESEVLRNQKKLDMADVIVFVHDSSDTNSFSYISNLRQQYSLDSLPSLFVATKSDLDLAQQRHEVQPDTYCRRLGLQVPVAVSARTGQIADLFQTICRIAMDPVHAIPGGDRSLTLASRLKYFAVVLGVATTVSAGAIFLFRALFRPPGAALVGLGWSWLPISRREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ90</accession>
    <name>M5FZ90_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623715.1">
        <property type="nucleotide sequence ID" value="XM_040769414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ90"/>
    <dbReference type="STRING" id="1858805.M5FZ90"/>
    <dbReference type="GeneID" id="63684476"/>
    <dbReference type="HOGENOM" id="CLU_541877_0_0_1"/>
    <dbReference type="OMA" id="RHEDEAY"/>
    <dbReference type="OrthoDB" id="2576334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="55100" checksum="A4F72ABF342AA3CF" modified="2013-05-29" version="1">MASPTPYNISLTSSSPEFIYSPFRGGSPASQGDPAGGWRSSLYDFDWTVWTGTLGTYQAGQPVREAYANGASVSLQFEGTAIYLCVSPTGSSYTFTVDNNPVTTSSPASSDPACANTDAQVMAYATGLAYGSHSATVQVNAGTGADFLFHGGVVTLGVTGPYPTVRRIDDTDPRWNLQPASTWTGYVGNEYTQASYNGTCTWTCSWGSAETASYTFSSERLSPPHVPDPANSISDSSTVLLIGKVSYDSGPFTIQLDGQSSVWNNSDLWWEEQQVLFFQSGLDPTTQHTIGVSNWDGADSNATRPSDPGSAPCFQFDELVLIQPGTLPPNASGSPTSSMPGASPTGKGSSGSGSGSSSFPVAAVAGGAAGGAVALCILALLLWLCFRRRPEPVDDEPPFPLPEDHMTQYITSAYYPPSTFSQAEYASQSTSQLEQGTISGQISDAPPAPAPAPRPGVGEPKDSGGTLRVLSASTLPPGAAPASPPGAGTAAVDGASTQALLTVLVNRLLRGNTLRGHEDAPPPEYDDAPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZC3</accession>
    <name>M5FZC3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione transferase</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_50567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630290.1">
        <property type="nucleotide sequence ID" value="XM_040774995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZC3"/>
    <dbReference type="STRING" id="1858805.M5FZC3"/>
    <dbReference type="GeneID" id="63690057"/>
    <dbReference type="HOGENOM" id="CLU_1161090_0_0_1"/>
    <dbReference type="OrthoDB" id="2098326at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03046">
        <property type="entry name" value="GST_N_GTT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000156">
        <property type="entry name" value="Glutathione S-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF9">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="76"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="239" mass="26075" checksum="99DB4D44C6FC959C" modified="2013-05-29" version="1">MATEQPATDVPADAPVAAPEPAPAAPAAPAEPAPSEPAPNESHPDEGKVVAPEIEAAAVPDVTPAAAEVVPVAQEGSRLVLHHLNNSRSQRILWLLEELGVPYEIKSYHRLPSMQAPPELKAIHPLGKSPVMQDGDVNLAESGAIIEYLIKKYGKGRFDPGEDGWVDNLYYTHYAEGSLQPIIVMSLIFSILPAWGGWSEVMALQGEVPRAHVFDVDWSANEQYCIILRYNTMRIRHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZL9</accession>
    <name>M5FZL9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_95005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628227.1">
        <property type="nucleotide sequence ID" value="XM_040777259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZL9"/>
    <dbReference type="GeneID" id="63692321"/>
    <dbReference type="HOGENOM" id="CLU_2542529_0_0_1"/>
    <dbReference type="OrthoDB" id="3376215at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="9295" checksum="843209E9E24DB6A2" modified="2013-05-29" version="1">MTFGVKIEEDFVMGKPKSSRVFIYVGSPTGNPNAWTDVTEKLAPEYSFPVKGPSFIESYEVTIQRLLGPRFGVSITIKTLYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZY7</accession>
    <name>M5FZY7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_56810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626019.1">
        <property type="nucleotide sequence ID" value="XM_040775398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZY7"/>
    <dbReference type="STRING" id="1858805.M5FZY7"/>
    <dbReference type="GeneID" id="63690460"/>
    <dbReference type="HOGENOM" id="CLU_004966_1_0_1"/>
    <dbReference type="OMA" id="ASARCEG"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305:SF1">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="1">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="280" mass="31234" checksum="88185AA5A3EA4BEC" modified="2013-05-29" version="1">MLSCAVTDGVLIGHPCCGVHNCAIPLSSNHAWYCPLHTGREASCAAEGCNNGAEPGRKTCSNPEHHLLEENYYAAGHSHHGGRKKAPGLKAHFGRRRMHNEQLIVHPCGVIVARGTFYGAESLSSVAEFIHGVFPTPQAMPDVMFYDNNCCLHQYLSGQGPIQEHFSKTALVVDVFHFKNHHSTADQYCSTHCNPMAFPQLYNQQSGQWTFNSSACEQTNAWLRNFDGIVQEMLPVRYEFFLDEVIRAHNHFCVDELQHNNALPYLMDRSLLLNGLNSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0I4</accession>
    <name>M5G0I4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_25112</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624210.1">
        <property type="nucleotide sequence ID" value="XM_040774015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0I4"/>
    <dbReference type="STRING" id="1858805.M5G0I4"/>
    <dbReference type="GeneID" id="63689077"/>
    <dbReference type="HOGENOM" id="CLU_723660_0_0_1"/>
    <dbReference type="OMA" id="CRFAAPH"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067382" description="RING-type E3 ubiquitin transferase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="264"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJT97312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="382" mass="41561" checksum="003ABE04A8B7F693" modified="2013-05-29" version="1">MITTCTFTFIQITAIIALLIVSSRVQSPAAPGYSQWDACPRRLQAFDIIQVGKAVIGWPVNVWWILRQPNESIPLSTMGRVAYRLRQDFIPYFTAILHIVLSAVLFSTLTGSPTAWDLSPTIFFACIVALFRTWLAVAEVVLLVVGGAIYAICYASLAIFCPGILPRRAVRLGGINPTIGPLSTTQLEQIPIVQYASMSTVSLVLPPPPSSTLGRLRLKRNDTSLSASRQAVGPKRHKIEKHRAACAICLNDFVDMKRVHNAPPVEQPRSAASHNTQFGTAPSSPLSLVSPAATRRSAEGTGVDVEQGNEATIPVVFLAPAGTSPLGEELPRPTPTEPEELRLLPCEHVFHKECIDPWLRDVSGRCPTCQRPVFGGEEDEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Y7</accession>
    <name>M5G0Y7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629298.1">
        <property type="nucleotide sequence ID" value="XM_040775047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Y7"/>
    <dbReference type="STRING" id="1858805.M5G0Y7"/>
    <dbReference type="GeneID" id="63690109"/>
    <dbReference type="HOGENOM" id="CLU_001324_10_1_1"/>
    <dbReference type="OMA" id="DYHKENR"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="8880" checksum="15542D9AC97A7A38" modified="2013-05-29" version="1" fragment="single">TDYKSQGCSLDHTIVDLARCQSPQSAYVMLSQVHTLHGLAILRDFDTEKIYCSLPSNLCNKIERLERLTLHTVRHHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1I6</accession>
    <name>M5G1I6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626584.1">
        <property type="nucleotide sequence ID" value="XM_040770475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1I6"/>
    <dbReference type="STRING" id="1858805.M5G1I6"/>
    <dbReference type="GeneID" id="63685537"/>
    <dbReference type="HOGENOM" id="CLU_412200_0_0_1"/>
    <dbReference type="OrthoDB" id="10669169at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="666" mass="72350" checksum="85663C300B4288FD" modified="2013-05-29" version="1">MSGPSPPMHPLSLPCHFVGASSSPGGLRCVCPAYDHQNGLSAFVLATLQPASNSTSCQNCGHPHSYHYPEAPSDLPIPPPIHTIPQSAVPFPSGPPSDHNLLANLISVMAPTGSSPYSAQHALRRVQANHAERTAINDQTSPPHPYHIALASRSQSMRLRTNPTLEQQHLRRHPIRSRHVLPPDVPRTIEFLVILRVYSAYPTPNDQIQGRTNIRFVTAHIPFLEAHNAAGLVRLLALPSTMRLPDLVTAIIRLFPAVIISQQASDSLRLIPEEARPFAPLRAVRNSLQPWTGLANLTLHDIVKESKKCVKLQRKRLSLPIAIEFAPTYDPLGSVHSSLFPSAFMNQFRCDTLNAGTGVEKLPLDLEQLRFLTAQLYLSSASPSSMPDQVSHQQSVTFPASLAPGNSLRNNPPPVCVSQPILPVPAMGPSLTVSRSFSPASSSNLSEAIYQPTCLPPVSHRRNIAIGSPPHRRTPVDPSSRTFRSSPHIALPHFSPPPSSSPISTSFLGNSPPMNVCPGVILNTSADSSHNTLINLLPSELSTSTPSLPLSSYTPGTQSSRLDLPASTSLFSTLQPKQPPPDVLTTDLRAVRWRWGLPSVPVLLSVSDEKNGDHTKQAWYLEALMVTKVCEGDLCIKLMDDTSRTRTWCCVVICVNGGVMKTKTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1L6</accession>
    <name>M5G1L6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631005.1">
        <property type="nucleotide sequence ID" value="XM_040772062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1L6"/>
    <dbReference type="GeneID" id="63687124"/>
    <dbReference type="HOGENOM" id="CLU_2209925_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11059" checksum="D8997172BF9A7D98" modified="2013-05-29" version="1">MGKAACAGSLLSFRASAGGVAYVACLPAECSLARVINTACEGLRSAQLSPGNDDVWGYCQARQIAGGGESGLPRRGSGPGEVRTPWGPRFEFRSSLGRVNTILISVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G8</accession>
    <name>M5G2G8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631305.1">
        <property type="nucleotide sequence ID" value="XM_040772161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G8"/>
    <dbReference type="GeneID" id="63687223"/>
    <dbReference type="HOGENOM" id="CLU_3037886_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="55" mass="6171" checksum="3EC2A21E611A8D98" modified="2013-05-29" version="1" fragment="single">MLQHPHQHQTPHIPEHTPRMPFPLPSPLTLKADRPPAPPTIHITPAAYPPYSRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2H4</accession>
    <name>M5G2H4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.256</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_111484</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4 14"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624865.1">
        <property type="nucleotide sequence ID" value="XM_040769245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2H4"/>
    <dbReference type="STRING" id="1858805.M5G2H4"/>
    <dbReference type="GeneID" id="63684307"/>
    <dbReference type="HOGENOM" id="CLU_017053_1_0_1"/>
    <dbReference type="OMA" id="VWDSKIT"/>
    <dbReference type="OrthoDB" id="4769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106073">
        <property type="term" value="F:dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028810">
        <property type="entry name" value="Alpha1_2_glucosyltferase_Alg10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR028810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="448" mass="49794" checksum="E30977BCC653C5CD" modified="2013-05-29" version="1">MSQKSPLPYIAFCVLNIYVLRSVNEVLLKPYMDEPFHVPQAQRYCSFEFDTYDPKLTTPPGLYLFSLGISKLFAMRCSLPLLRFHSTLLLLSLPPILSHLLPLLQPPPCSEPPRTFLETLRPGWEAIVLGFMPVAWFTGFLYYTDLGAVVFALGAIVAAKRGQSGLAALLGTVGCLFRQTNIVWLGYAASLQALEILHRPSPSKPHLADPTLSLTSPTLLLRTLLSLPSLCLSRLPELLSHLWPYVLPLTSFCAFVLWNGGIALGDRAHHEPTPHWVLPMYFLVFSTALAAPALAGGPLGVLGLGRVVASKIFSTPRRIGFTLAWTAVLCILINRYTIAHPFLLSDNRHYPFYLWRRLISPFPLARYLWAPVYLLCFRIWTIRLGEQPLLPLLSLAICTLATLVPTPLLEPRYFIIPFLLLRCYLETSALGVAGEGLGIETPLGMPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2P7</accession>
    <name>M5G2P7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Daunorubicin C-13 ketoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_111018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624935.1">
        <property type="nucleotide sequence ID" value="XM_040769162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2P7"/>
    <dbReference type="STRING" id="1858805.M5G2P7"/>
    <dbReference type="GeneID" id="63684224"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="NNEYADH"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="36189" checksum="9187134ACCF5869C" modified="2013-05-29" version="1">MFGRRWNPVTDIPDLTGRVAIVTGANIGLGYQTALQLANHGATVYLTTRSEAKALDTIKRLEEANPSLTDSGRLRWLELDLTLVHNAKAAAEEFLKKEARLDILVNNAGQMAADFEVTAEGLSHIMASDHVSPFAFTTALLPLLEKTARLPDADVRVVTISSIQHSYAPTSTKFVTPADFRDMCGPEESVNSSILQQTARYGQAKLANILFARELQRRWDAAGIPGISISLHPGVVHTAGAERVARSFGAGILWPLVTLFIMTPPQGAITQLFAATSPDVRQNVEKYKGQYLVPYGSVATPSAMARREGLAEELWNLSEKVVQEILEKGKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3E6</accession>
    <name>M5G3E6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_78081</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630088.1">
        <property type="nucleotide sequence ID" value="XM_040776310.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G3E6"/>
    <dbReference type="GeneID" id="63691372"/>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OMA" id="IGMAAPY"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000102">
        <property type="entry name" value="ABC multidrug transporter Mdr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000066">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="776"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="823"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="895"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="924"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1006"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1040"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="102"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="436"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="780"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1102"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU03194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1351" mass="145995" checksum="925FBC389B30A6AB" modified="2013-05-29" version="1">MADIEKQLLQQQTRPPDGVTHTGSNSPLEIKVEKSGTGTPDEDSAQQNKKVKSPLFARRKPAKEKKLSSDGKAGGTTDDDIKPVAITALFRFATRFEIFLDIIGLICAAAGGAGLPLMTLIFGNLVTAFVNFTTVALTGDPALIAPAADNFRHVSAQDALWIVLIGIGMYIVTHAYMWIWTYTGEVNAKRVRERYLAAVLRQDVAFFDNLGAGEVATRIQTDTHLIQQGTSEKIPLIMTFVAAFITGFIIAYVRSWRLALACTAVIPCIGITGAVMNHFISIFMQRSLKAVADGGTLAEEAISTIRTAKAFGTQHILSALYDTHVQRAHNADMKAAVSLGGGLACFFFIGYNAYALAFYYGTTLVLFGIGNVGIVVNVLLAIMIGSFSLAQMAPEMQAVSNARGAAAKLFATIDRVPTIDSASTEGKKLDNVEGRISLEHVSFNYPSRPEVRVLNDLTIHFEAGKTAALVGASGSGKSTVVALVERFYDPLQGGVQLDGHDLRELNVSWLRSQIGFVAQEPTLFATSVRQNVEHGLTGTPLENLSPQEKLALVKEACVKANADSFISKLPEGYETNVGQAGLLMSGGQKQRIAIARAIVSNPKVLLLDEATSALDTQSEGIVQNALDKASQGRTTITIAHRLSTIRRANQIYVMGEGRVLEHGTHNELLSNKEGAYSSLVSAQKLRERRDGQQDDKEDGVDDQAEKLEGPLMTDAEAQAAAEAEIPLQRTGTAFSIGSEITKQRRQEGLLPDQQVDKTYGFPYLFRRIGAINLSALKFYAFGSIFAIGFGMIYPVFGIVYGITLQSFATNTGSALRHAGNMNALYFFIIAIAASVCGGGMNSLFGVAATHLTAKLRSISFSSIMKQDISWFDEDRHSTGALTANLSDYPQKISGLGGVTLGTILQSATTVVGGAIVGLCYGWKLALVGIACVPFVIGSGWIRLQVVVMKDEKNKAAHEESAQLACEVAGAIRTVASLTREKAACREYSDSLEIPLRRSNRNSIYSTALYALSQTLGFFTIALVFWYGSRLVASQEYDTQRFFICLMSVTFGAMQAGNVFTFVPDISSAKSSASSIINLIDSEPEINADSTEGKKLTDVKGQITFHDVHFRYPTRPGVRVLRDLSIQVNPGQTVAICGPSGCGKSTTVQLIERFYDPLAGGVSFDGVPITELNVGEYRKHIAIVSQEPTLYSGSIRFNILLGANKAAEEVTKDELEEVCRDANILDFIHSLPDGFDTEVGSKGTSLSGGQKQRIAIARALIRNPKVLLLDEATSALDSQSEHVVQEALDTAARGRTTIEIAHRLSTIQNADRIYYIAEGKVTEEGTHDELLRMRGGYYELVQLQALSRADMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3R0</accession>
    <name>M5G3R0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Metallo-hydrolase/oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_118682</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625295.1">
        <property type="nucleotide sequence ID" value="XM_040770639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3R0"/>
    <dbReference type="STRING" id="1858805.M5G3R0"/>
    <dbReference type="GeneID" id="63685701"/>
    <dbReference type="HOGENOM" id="CLU_030571_1_1_1"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39713" checksum="BE57B0035BA3E4B0" modified="2013-05-29" version="1">MAAKAHHIDPLSLPFHPIPASTSPGAVVNLTVLNCGEITTRWVHFRQRETAEEMRERETGVVFAWVIEKQFDDGKVERWLWDAGVVSHPNDLGPTLAASFGPRFIFDVPPSARLPGLLEHLSPPPATLSTLTGLLISHSHMDHYGRLSDFPASLPVIFGPGTKAWVEAGVEQGRPIPKTFWEHPDWIGEVGEEGAKGRGKGWEKVGSYEYAWDWFGDGSLWLAQAPGHCPGHMVALGRVSTSPDTYVLLGGDTCHSRPIYSPFPSPSARWPCACWADPSEGPDAKPSHTMHLDLPLTYESIARLTRMEMEENVMCVLAHETEVARELGIGIGQMKGGWEAWKELGWKRKESGEPPKKGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Q8</accession>
    <name>M5G4Q8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1753-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_77364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630558.1">
        <property type="nucleotide sequence ID" value="XM_040776265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Q8"/>
    <dbReference type="STRING" id="1858805.M5G4Q8"/>
    <dbReference type="GeneID" id="63691327"/>
    <dbReference type="HOGENOM" id="CLU_063116_0_0_1"/>
    <dbReference type="OMA" id="AWTVFFA"/>
    <dbReference type="OrthoDB" id="3338076at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070917">
        <property type="term" value="F:inositol phosphoceramide synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006673">
        <property type="term" value="P:inositol phosphoceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013862">
        <property type="entry name" value="Kei1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077:SF1">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08552">
        <property type="entry name" value="Kei1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="290" mass="32493" checksum="227679B1773404DC" modified="2013-05-29" version="1">MWLRLSRPIWPLTSFVGLMDLKTGATVILLFALLNKVAGVYGLITIVTGGSIAQLSMYFYSIVMLVAIWWLGLRIILSENPRYTFWIAYAFLLDHVITTIWLAYFALEWWIWTPHDGRRVAHSAAQEALINSVAGHNMTDAERELAAQAIWDKEKGTAGGVVVISWLVKWYFIAIMFSYALRLRAGNYHSLPSSNVPLSSLPHPDPDTGFLSDEEDDLAREEMALQQIRSPTSAREPDTATSMGSFRTAPVRGIGNGTPLGSPYTASPGRTRFERNEVLWEQQGDEDRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G513</accession>
    <name>M5G513_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630643.1">
        <property type="nucleotide sequence ID" value="XM_040769931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G513"/>
    <dbReference type="GeneID" id="63684993"/>
    <dbReference type="HOGENOM" id="CLU_1454357_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="186" mass="20068" checksum="3E2B65B9674E022C" modified="2013-05-29" version="1">MSSPGASHMTTVGTAPQFFVAFGGSIASPALASPPNVHLGSQATGLINLGIELANTRHQAAQAHLRHVDVYQNLVHANHISDGTVRGHEAVQMARDEVWEAQRVVQRSQRTLDYLLIMAHAVQTGSGVQTPAYSLQGSHSNSFNNNMVHVHQANQSKLPFDFFKFVQKTLNVPSCGKLFPGAFNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G634</accession>
    <name>M5G634_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Clathrin assembly protein AP47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_79814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628179.1">
        <property type="nucleotide sequence ID" value="XM_040776415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G634"/>
    <dbReference type="STRING" id="1858805.M5G634"/>
    <dbReference type="GeneID" id="63691477"/>
    <dbReference type="HOGENOM" id="CLU_026996_0_0_1"/>
    <dbReference type="OMA" id="KPLIWCD"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000006">
        <property type="entry name" value="AP-1 complex subunit mu-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="167"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU01282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="435" mass="49893" checksum="4AF4283261948A6F" modified="2013-05-29" version="1">MASLIAILDLKGKPLIQRTYRDDVSPSQIERFLPLALELEEDGQAVKPCFSSGGVNYMHIRHSNLYLLALSKRNTNAAEIIIFLHRLVSVLIEYFKELEEESIRDNFVIIYELLDEMMDFGYPQTTESKILQEYITQESHKLEVQASVPITVTNAVSWRSEGIRYRKNEVFLDVIESVNMLVNANGNVIRSEILGAVKMKCYLSGMPELRLGLNDKVMFETTGRTSRGKSIEMEDVKFHQCVRLSRFESDRTISFIPPDGEFELMTYRLSTPVKPLIWVEAAVESYRGSRVEYMVKVRAQFKRRSQANNVEIFVPVPEDADTPKFRASTGGVQYAPEKSAFVWKIKQLGGGREFLMRAHFGLPSVKNVDDVDRRPPIQVKFEIPYFTVSGIQVRYLKIVEKSGYQALPWVRYITQSGDEYAMRTLQEKDASIQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6T2</accession>
    <name>M5G6T2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_76864</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631308.1">
        <property type="nucleotide sequence ID" value="XM_040776229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6T2"/>
    <dbReference type="STRING" id="1858805.M5G6T2"/>
    <dbReference type="GeneID" id="63691291"/>
    <dbReference type="HOGENOM" id="CLU_014673_2_2_1"/>
    <dbReference type="OMA" id="SCRERRY"/>
    <dbReference type="OrthoDB" id="25767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF5">
        <property type="entry name" value="TRNA PSEUDOURIDINE(38_39) SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="6">
        <location>
            <begin position="254"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="467"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="506" mass="57211" checksum="3EDC66011F76F235" modified="2013-05-29" version="1">MAQANLAKYDTWSRLQLIARLNELDIQKEKAENEKDLTAKARELPRPYVVSSRPKRKIALKFCYHGWEYCGLEKQKGYTPIPTVESVLESALIATRLIDPVEGFEGAGYGKSGRTDRGVSAAGQVVSLWVRSMVAGGANDGERKEAEEVNLALDDEEVDDSFEPLTESMELVSQLLAEQDTPEVLVDDTQHLLPTEGEIPYARVLNRVLPPSIRVLAWSPVHSDFEARFSCIGRHYKYFFRLHPGLDLSRMRDAAARMKGTHDWRNFCRLDGSKGDVRYVRTIEDVTLEPVAKDEDPTLYVLNVQGHGFLWHQIRHIAAVLFLVGQGLEHPSVVTSMLNTDQSNPLPPFREDEPLPEIVEGKPNYEMADALPLVLWDCRYSDEDLNWIPDEPGYSQGFVQSLETTYTQSLMQSTILSYFTRAAELRPPPVSASAGEFGRRDCVLLDMGAGRFKVNIKYKPLLKRERGSTPDEVLRRWREGKGGRRAEKRAARAEQDEMRETGDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G729</accession>
    <name>M5G729_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Osmotin thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_48068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631423.1">
        <property type="nucleotide sequence ID" value="XM_040774804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G729"/>
    <dbReference type="STRING" id="1858805.M5G729"/>
    <dbReference type="GeneID" id="63689866"/>
    <dbReference type="HOGENOM" id="CLU_043181_0_0_1"/>
    <dbReference type="OMA" id="AGGNCEP"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067506" evidence="3">
        <location>
            <begin position="17"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="26"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="95"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="148"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="153"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="32789" checksum="F6C541C3E44D79F7" modified="2013-05-29" version="1">MHLSLLALVFVRVVTAVRTFTVYNGCPFTVWPAIYTNLAAGTAVPQYQTGWQADAYTTVNFSVPDAWTSGRIWGRRDCTFPAGNTSASTCLDGGCTGGLLCDVNTGTGMPPATLAEFSLGGTTGTDFYDVSLVDGYNLPIRITPTSGCAVAECPWDLGPLCPTTLAGPFDSTGYPVGCKSACIAGVDGNPSKSPNCCSGSFNTPQTCPSSGVAFYWFFKGYCPNAYAYPFDESSGTALWTCPSNNLADYTITFCPAPDGAEPSVSPPSTSTSFAFESTTSWMSTPSSMNIMSTTTGTTQPAPGSDTLPNSSVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G782</accession>
    <name>M5G782_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632990.1">
        <property type="nucleotide sequence ID" value="XM_040769527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G782"/>
    <dbReference type="GeneID" id="63684589"/>
    <dbReference type="HOGENOM" id="CLU_1294364_0_0_1"/>
    <dbReference type="OrthoDB" id="3243413at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="213" mass="24586" checksum="66BF9C2A9267F9AE" modified="2013-05-29" version="1">MVKRSDTPPPSSEEPRILCVKLPYPEVQPIDFEVHGGAEVILAQWLAQIIKKDSLFYIYWMPRNDMILVSVAREKDGFYNSILGEHRWGAFLKNCRRGWEKHVSTIFYSTYNTDRDVQRSGWRQKWIEASWFDDDYSSTFVHPYPDPIYTTIIPDSCRAIPAARRNVPVSIGASKWLVTSVDRDVPGAPVRTVTEDKKKRKKYSGQVGSLPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7I0</accession>
    <name>M5G7I0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_66769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628724.1">
        <property type="nucleotide sequence ID" value="XM_040775826.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G7I0"/>
    <dbReference type="GeneID" id="63690888"/>
    <dbReference type="HOGENOM" id="CLU_004288_0_0_1"/>
    <dbReference type="OMA" id="NSLEMIC"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
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        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF31">
        <property type="entry name" value="DENN (AEX-3) DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="340"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="883"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="963"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1044"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="759"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="843"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="883"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="966"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1227"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1360" mass="149534" checksum="9FBD979FCAC81A28" modified="2013-05-29" version="1">MPSPRPGQTHISNVSAAAAAASSRYARPRAQRDTSATSYPSSDFDAAVAAQAPTGAQNGHARRERTDIEELEEDDDEEFEAGGATTQGEMDPPPSIPPPMPHHHVHGHHSHAQQGALVPAPKGPSRPGTVASQHQKQLSSGSKNGALTQPAAPASTTPLTSLYLVAGLPKSPHTWTLAEPDSVEGCRHADGAVNRWWRAEVLGSTVSPGVNNGGDGSTVGGGKKRKSRRGEDVQRMLSKALKLSFPKEVEIIASTLQPASTIHTFTFTLRPAGPHSMNRAATFTSLSNASSLPSLRPGYGPANYSTTSFQSFNPPPVPNSNNAPLKGGKKEEEEGQIYYGTVLTVYSHADASRAEAIRKSLSQPTTGTPGASPGSRRFQRRPASSARRKAPWNGQSTPEATETEQEPETDDWGDKVVGGSTLFLPRETVFWLPYALTLVSKHPIYDLMRDFLTLSWARFSKDVQSHSLQIAKILEHPSPRSGDIVKLDAGAEGESVEVVCRFPGGLDFGRGLVDVNFTMWPLFRALNLDNILTVCEIALAATGRVLFLSRYPAMLGIAVHTIKYIVELRGWNGIAHPAVHARDAKIYLEDPGPWLIGLHTDCRFVARPSKEVCICDLDINSVHCPSPPAGSVSTKQQRDKFRRTLINAFEGYFHPDYAVPSEFKEAFPAGRFRPLCSIKTRRGAPSAVYAEIIPPPEWWFQPRVIQAFDSVLKDKYKKPSLLKRLAMLGMSKRQAGLTAAEQLIQRAIRRRATAFVDARDDLETKIGRLSRRLNFLMTESDLWREKFVAFEGYAEKLSLEAGDLKSKIGKEQRESRRLSGLITVTAQEKQQLQMRLSHVEHEHQDALMQLDQMRLNMEAMEREREQMVAEVEEQIERALASMSFNDSMSETGTSRTGSRADSRASTPGLANGRRIPRSFSTGTALHDPVDEELVEHEIGMNAADIETGKRRLEKIDEREIDEEEAEVKLEPRRQRHYKEQKYDEEHDSDRSAIPVRKKRFSASGRDQGTEDTMGAVDAGISEKSERISEKVNQIQMKLELALADLENKRRVASPRSGADDTGGETDATRRSRRTRRRVKTSHSAHQAEAEAEADTSLEQRLEQAPPAGDRLEPLHSTVEQRLSPALSRAEKKRSLDEMSEATYRPSAAERSGEIDEPDLEPVPEMINEVVEPVDIANEEEAVIEPVDHAEDADSEASSQRDIKRESTSTVVAEPAQTPIKSASTPSPIAPPRNPSRAPPVSSSGRAAAILVQETPMDAAAPALSRKTSTRSKRLSRMTTGTTSGGESDADFVSAYSSSPIDKSLMDDEDDEGEGMSPVPGSWDDDEDLVEPRHIRQRVSSTATEVPDSRRYRSFNAVSMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7M5</accession>
    <name>M5G7M5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633080.1">
        <property type="nucleotide sequence ID" value="XM_040769532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7M5"/>
    <dbReference type="GeneID" id="63684594"/>
    <dbReference type="HOGENOM" id="CLU_1704177_0_0_1"/>
    <dbReference type="OrthoDB" id="3347279at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="16474" checksum="0227B949C4710631" modified="2013-05-29" version="1">MPPKSRATSRPVEVPDEAPPTASMFDPDRQSAPRTPAQASRTLTGAGIPAVTSTPANFIPDTSDNSFRSAILSASQLNLTPQRPGFSAPSAVDLITQSPIPSSDSHDTIQERASYGPGAQKTPVKPRGIMIREDPSMVSSFDPKDEVLYKLWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G806</accession>
    <name>M5G806_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_107730</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628904.1">
        <property type="nucleotide sequence ID" value="XM_040768520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G806"/>
    <dbReference type="STRING" id="1858805.M5G806"/>
    <dbReference type="GeneID" id="63683582"/>
    <dbReference type="HOGENOM" id="CLU_421511_0_0_1"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="11">
        <location>
            <begin position="20"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="351"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU02007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="650" mass="70354" checksum="B1DBE85FCA3F11D7" modified="2013-05-29" version="1">MSLPPLTAPPPSSSLNPNSTFITRTASTLYLGSSPYVVAGPNIYWLGIDENDPPGSVTYPSRQRVLEVLATAYAMGANTVRSTTLGVSVGCDLCVWPRLGVINGQALQVVDFAVWAARLYGLRLVIPLVDNYEYYHGGIYSFLQFHNLSTDDYSPFYDTSSAVYDSFLAYITTILNHTNPYTGLRLSQDPTILAWESGNELGGWGGSGAPASWTAALAQFVKSDLGAKQLFIDGSYGIVRDALGIGQVDIVSNHHYPPYTSKLFSDARTALAADKAYLAGEFDWVSHGSSPRMWALVAGPALLALLVFALPGRWFPWPIRYGCLYREKRKRAGSAEGVGVGAGGARQMEMADQPETDAEDSPPPLRSSPPPSSRPAYPELSPRNKMSRPSYKRQDTERAERWRLFEDGAEGKMPFLERIGTGTGMPFSPPPAPPSSAAPPVGSPPGSPQGRASRLSQHTPRSPSQSGTHSHSHHIPPTTPKRPLYTPTASYRSSHARTPSPLPSLLMSLKPLPAEREPHTFLFRKWHFALVIFLLLTPAVALLLHFLLPSTISSFTSALASTPGVSGGLYWSLFGHTDTCTSYVYHGDGYWLVYPGQGGFMSYRVGQLVVWERGVSGYGLQAWGDAGEPTVACKQAVNLSLLPNVSMGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5G836</accession>
    <name>M5G836_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pks1</name>
        <name evidence="8" type="ORF">DACRYDRAFT_113090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633270.1">
        <property type="nucleotide sequence ID" value="XM_040769561.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G836"/>
    <dbReference type="GeneID" id="63684623"/>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OMA" id="VIFDISW"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="6">
        <location>
            <begin position="7"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="7">
        <location>
            <begin position="883"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="883"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="916"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="2512" mass="271095" checksum="52814B2D6FDA5793" modified="2013-05-29" version="1">MANEFEARKIAIVGFSCALPSGHYAKEDLSYNMLWDFLMTKSESYEEIPQDRFDINQWFGKNAGQISTRKGNFLKNPTQFDHIEFGISLKDATALSPSSRKLIELAFLALQDAGIDYRGKRMGCFMSGINSGLVDRDPFDEQGSFANAPAMPANRVSYTLDINGPSVALDTACSSSMTGTHLAIQSLLGGDCDTALVGSCQYDHWLQDWVGYSVGGVLAPDGKCKPFDAGGDGFSRSEGAGVFVLKPLDKALADGDKIYATIIGSAINSTGGGSAPNQPVGSAQQEAIKLAYQRAGKDPRTVDFVELHATGTAVGDPIEANAVGELFNRQEELIVGSIKGNMGHLENTAFIASLAKVCLIFEHGIMPPQANLKSLNPAIHWKKYNLRVPFESIPLDVNLGSRPILTSISSFGIGGANGHAILESFVSAAGDYTPTVKNGPYLIIGGGLTPKSAGTVASDLAAMLEEHPEQAAEISRISIRRARQLLWRTAAVYESGKPISFPEPTSVPRVVPPIVYVMSGQGPQHFDMGRQLYAENPVFRASIDEMDDIYRNYAGVSLIESTGLFRTLEKPALKLPAIWSIALILPSIAMFQMAMVDMLTSVGVHPTAVVGHSAGETALMYASGASPKKLALEVSIARGRAMALLEAHKGTMAAMACNRQQAEALMSTPELGKDIIDIACHNAPDAVALSGPADIIDNIMKAAAEKNIWARRLQTNCPVHGTMMDICKTEYQKSVGHVFRNNPPVTEPTIQTFSTLSGGILDQSLSAEYFWKNARNTVLFTEAMTAIRMSHPNAIYVELAPHPVLSSYITAIVGQPAPVTCPAKRARKGETTKEMATFLTSVGELCLKGYNSVDVKTVPRIQANGLILPAYPFAQRTVPWHSESDLGRSRFRVRNGPLNYPGIHVNTGTHPDLADHIIQGEPIMPATGYLEIAFESGARQLWDVGFYAALSLSSARPAPIEVSVDGHSWTIRSRGPRSKVFDRVNAGGYLSKDSAVRPNANLEAIKARCKAVSAKTFLDSLTFANFGPGFRRIEELYNGNGEAVAIVRGWDDKYALAAGYQFNPAILDSCLQAAYTLVPGRDTSDMYFLPARCGYIALNDMSTIERPSSVVAHIRLAAWTPEAITFDYHVYTPEGQWLCSMESFTMDGHRGIPKKPVDNRLESVWQPIRIPAIVPAPEKVSSTASAVSDLLTALDAAAVKAMSSVVASNPVAPDDVSRQRYLAFMQKAAESGRPTTSMEVEEQLKEKFGAPFEILQRVAQAQEKLLTTVDDAVVDGLFKDNILMELYKPDGIMGAVSASLAEQFRKTVAHVVNSGKRVLKVLELATGSGSLTAALEPIIHEFPGIVIEYVASDAAPAVLGATLNRLGYHKMRSQTFDMSKEPESQGLVLNSFDIVTGLNVLHTVPDISVALVGLNSLLVPGGSLLIADIDGAQWGSIPGALWCDFVFGVYKSWFSYTDARSHAAPSANEWSTQLETAGFNVVARLRDADGPFVMLAGQKDVDISPVAAPAIGEVLQYRLGHEGQIQHVFKKYSPEDSPTFWIAAPEGLDGDGVLGFARSLQKEFPTWTIKLAVFSGERTEAEQKRLLSAWSSRLQHEWEVHFDLHGEASVMRIAPAVPCPTPGMVAFDPAKPWAIQDGTVVQTSLPYVGKDDVLVQVEVWHSLGTALKAFVGRVGVVPSGGFQENELVAGITAQNEASCVTALCTSLARVENKKLTSQELVSIVGLAAVASVINADHKASQRTKTPRRALILNDPTTESLGAILKRLNWDVSTQEQLFNAGIRRTALPVFDVIIGTTETVSALRESPKSLPYPSFCWDDASDGLLVRSRQMAFGEDLEAVLGVVDKQSLTPHVSESATLLPPPGALVKNASSLLSPTKTYLLVGGIGGLGIRTAAWMYEQGARYIVLTSRSGEASLARLNEPVINNVVDYLKSLPDLTLRLEACDANSSSAVKKLCNTFAYPLGGALIMAVVLQDRVFMDQTAETFRSVYESKVGAYKTLADVYDLSTADWLVMFSSVAGLFGNGGQTNYASANTVLDAIVGKLPNAFTLIVPPILDVGVFARAAQENAAAFAHLKDWGMTCEDLCDYIGDGIKRLQETGPFTFQVPDLNWLAVEKTMGISSAFHHLAYPPRSDFADGGAGGEEKTIDDVVCEILQVPKDDLSQEVPLTRYGLDSLSAARLAAGLRPFGTISQLQLLSDLTVFDIKAKLGDGAAPAGGAGSDGRGASPIVKIKDDGSVPIIMTHGADGSIAPMKMLSENFKGSVWAIQLTGDAPMESLEVLADWYYDHIKAARPQGPYRLCAFSASGAVMVYLCKKFEAAGDQVLQLGFVDHFPLATMGGGFDLRIAVDKDGMLLPEYMKIIISRMGPMMVRDSKIDPVRRTLGEDLNKWVKGEETSELATSFIDIVRNYASLETRWIIKKITGGVTSAPWDPKVYVRWLQDIKAPTTMIWGLDGYRNDLPKEWRNPGHVFDAHSVYPDAKLIEVPGGHAECLASKEAADILAEGFSVGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G896</accession>
    <name>M5G896_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23510</name>
        <name evidence="2" type="ORF">DACRYDRAFT_23542</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626875.1">
        <property type="nucleotide sequence ID" value="XM_040773272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G896"/>
    <dbReference type="GeneID" id="63688334"/>
    <dbReference type="HOGENOM" id="CLU_2236495_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="105" mass="12020" checksum="10EFA561BE3E6D3F" modified="2013-05-29" version="1">MRVARMQEEKFRPPQRVPKRWQVKAQGFEERLRVSYVVLHAGLMSASVSVDRERTTCMLVFVCLWAECWSVLAQEAAGRIKRPKVCTNACGSTCYCAWSPAHTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8S8</accession>
    <name>M5G8S8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_21962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629154.1">
        <property type="nucleotide sequence ID" value="XM_040772624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8S8"/>
    <dbReference type="GeneID" id="63687686"/>
    <dbReference type="HOGENOM" id="CLU_043560_0_0_1"/>
    <dbReference type="OMA" id="QAFIGFC"/>
    <dbReference type="OrthoDB" id="409948at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE/SOLUTE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567:SF1">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="206"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="385" mass="41865" checksum="8B41F4D0FF16F6FC" modified="2013-05-29" version="1">MTVDDPEAQPLLNGKPADPPSVAADAEPSSTETTPLLPPQPEPSTWAPKSDADPPPGVRVNPEDLPGHVPPEEQRRRLIWWLIFWLVFSSFTTVCVVLAIVKGGAKFDFMGSLKKAIGGGVSGAAAMVIQVLTLMPLRTIMNFQYRFGGTMFSSSKELWREGGVTRYYAGLTAALFQGPIARFADTFANVGILALLSSNPVLEHLPSPAKTAFASVAAALFRTILVPIDTVKTTMQTQGRAGWGILKDRVKAYGIGTLWYGAIATAVASFVGNFPWFATYNWLSEVLPPAEGVQRLLRQAFIGFVASVVSDSVSNSLRVLKTYRQVNQSKISYYQAALRIIQSSGYASLFLRGLSTRILANGLQGLMFSVLWKLFQDMWEGKVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G945</accession>
    <name>M5G945_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631589.1">
        <property type="nucleotide sequence ID" value="XM_040769747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G945"/>
    <dbReference type="STRING" id="1858805.M5G945"/>
    <dbReference type="GeneID" id="63684809"/>
    <dbReference type="HOGENOM" id="CLU_038942_4_0_1"/>
    <dbReference type="OMA" id="RCQNNIR"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="368" mass="40066" checksum="FDDA6BDE05338F6A" modified="2013-05-29" version="1">MPSLLLRKYAALTATLSIPIPSSSKSVCNTLLTIINDPHLTSYPPSHAYQTRFFKRLVDELEARADYPIDEEIYEAFMDAMAGSSSEGCSNHSTSSPGLQVTPPSPSYRTHYYPLRLSSRGQENGHRSPPGCLCAREQADEEGWGRLTVFESPSLVEAGTTGLRTWRAALWMGEWLLAHSEVVKGKKVLELGSGTGFLGILVAQLQLLAGEGNGVGEVWMTDCSDAVLHRCANNVHLPCNNLEAHPGLHTTSLDWTSSLPEVEAQMQQMKPDVVIACDVVFDTSIVPDLVKALRLTLGTAGACWVAGAIRNEETTNAFIREAENQGLRVRDTDWAFGDDERVFLGGSEGGEGMGEVRLMCLTKGVKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G960</accession>
    <name>M5G960_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_46471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632183.1">
        <property type="nucleotide sequence ID" value="XM_040774706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G960"/>
    <dbReference type="STRING" id="1858805.M5G960"/>
    <dbReference type="GeneID" id="63689768"/>
    <dbReference type="HOGENOM" id="CLU_055194_0_2_1"/>
    <dbReference type="OMA" id="WIQEKKE"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="54"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="10">
        <location>
            <begin position="211"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="287" mass="32139" checksum="C89253B60C59BE16" modified="2013-05-29" version="1">MSRPEHIAPPEIYYGDAEARKYTENSRIQSIQSAMTLRALELLALPPDEPAFLLDIGCGSGLSGEILDEEGYNWVGVDIAPSMLAEVALEREVEGDLFLQDIGQGFGFRPGTFDGAISISVIQWLCNADVSFHSPPKRLQQFFSTLYASLVRGARAVLQFYPQSDDQVTMITSIAMRCGFEGGLVVDYPNSTKAKKYFLCLFAGSPVAAEGKKAKVELPMGLQGEGEKAIAYERRRGLEKRGRRKTDKKGVHDKEWILRKKELYRQRGKAEVPRDSKYTGRRRKFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9F6</accession>
    <name>M5G9F6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_54453</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627325.1">
        <property type="nucleotide sequence ID" value="XM_040775258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9F6"/>
    <dbReference type="STRING" id="1858805.M5G9F6"/>
    <dbReference type="GeneID" id="63690320"/>
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        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
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        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
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        <property type="entry name" value="Pro-kuma_activ"/>
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        <property type="entry name" value="SEDOLISIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067601" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="17"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="233"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="311"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="601"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
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        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="622"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00004239"/>
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            <dbReference type="ARBA" id="ARBA00012462"/>
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            <dbReference type="ARBA" id="ARBA00022525"/>
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            <dbReference type="ARBA" id="ARBA00022670"/>
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            <dbReference type="ARBA" id="ARBA00022723"/>
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            <dbReference type="ARBA" id="ARBA00022729"/>
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            <dbReference type="ARBA" id="ARBA00022801"/>
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            <dbReference type="ARBA" id="ARBA00022837"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023026"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023145"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="643" mass="69635" checksum="51088E59C0E50270" modified="2013-05-29" version="1">MLAGFLLLAVPWAAFALPSPSIAVKRTHERRSVLPHQWEEHSDAHPDMRVPLRIALTQSNLDVAYDELLKVSDPESPDFANHWTAKQIAQFFAPSKETVDTVIAWLEDEGIDRSRVKQTDSLGWLQVANLSVTEAETLLDTKYRIYKHASGAPHLGCGSYSVPEHVSKHIDFITPTVHFDSPVNAHRQEKRKRDVEPGIAKTIGQPRIGTTPKQGASLSVPNIITELEQCGSQITPICLQSLYKMPFDLQLATSKNSYGIVEYTPQSYLATDLDMFFKQFLAKAVGQRPTLDSIDGGEPQTELEGFGYNGESDLDLQYAMALVYPLNPTLFQAGDIVEGASFNNFLDAIDGTYCTYEGGDDPTQDGVYPDPNGGGYEGTENCGTYAPTYVLSTSYAYNEADLTPFYEQRQCSEYAKLGLQGVTVLYSSGDNGVAGNDGQCLTANGTYSASGTRFNPSFPGTCPYITSVGATQIKPNGTVFEAEEACETVIYSGGGFSNVFPMPSYQASAVNSYFEKYPPPYTAAQYNNSRTVRGFPDISANGANYVIAIDGEFDLVYGTSCSSPTVGSVITLVNDARLAAGKKPVGFLNPTLYANPWMLNDITTGGNQGCGTAGFTSVPGWDPVTGLGTPDYGLLVAKYLTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9U7</accession>
    <name>M5G9U7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9U7"/>
    <dbReference type="GeneID" id="63683379"/>
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    <dbReference type="OrthoDB" id="413993at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="734" mass="80935" checksum="C657761FEED378CB" modified="2013-05-29" version="1">MDFNSARFLRPSAYLKQTLLSSPSSSYSPTTAPTLPSHCSPQLSASPPSTSSSLSNPPLNSILQVMGNERQEMEDDSWTDLLNLGSQSTNSTLRASQLNTQMETPAFGGFSDDLIFPIELEHHRSPSNHASIQDIFPSHFSPILSSVSPSPTFMHAMPGSGPASMPFSPVHAMTPERRYFQQSPHAAEIALQSRMSPFAGYESEGYQTDPLSPLTNGQFSNMHLSDTMSSPMQGYMTNMSQSAPTQHVPFADIFLSNGSLNPLATQLRTAPALSPSPKIEPEPELDANHADDDDSVDSTPELDTDDADRPVRKHTRIPLPIPVPNLTKKSRGRHVPTLPSSQTGQLGIMHSASSRDEVMAASKIAAEQLASVSSTHLPPAELLAHLTDVHCHPTDSDTPKDVMEALVIRVCAMATRSDDQEKVADLAREWPDKVTPCFGYHPWFSHTISLLQKLPNKEEHYASILLSGKDASPENSLKLQEMLPLLPEPRLLKDIVAEVRNNLVAHPQAMLGEVGLDRAFRIPMRPYPSPPPRKLSPFSVPMGHQLAILEALLGVAVALKRNVSMHSVKCQQVTVELFKRMKALHNEKWGSINIDLHSCGFSAETWKEVERNYPNVYLSLSTTINAKNGGVAALIQAAAETRILIESDWHDITLCTGSAWDILRYIAEVKGWRVEDTWEEHVQGEPGAVRRIEENWNSFKSGGKGLAPEHIASNHRDRRRRDHSVDELDSDVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9X2</accession>
    <name>M5G9X2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632009.1">
        <property type="nucleotide sequence ID" value="XM_040768014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9X2"/>
    <dbReference type="STRING" id="1858805.M5G9X2"/>
    <dbReference type="GeneID" id="63683076"/>
    <dbReference type="HOGENOM" id="CLU_025691_0_0_1"/>
    <dbReference type="OMA" id="PREPTEH"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="52923" checksum="B98E2457340DE386" modified="2013-05-29" version="1">MFTRITSSFRRTSLPLPQPTQSQYAPPPAPDGTLSTLSPAQPALEPHPETDDLPIYISPSELARSVHTFALKTNGEPWLSLSLSSSAGQATSHPLFFDTAVFQGNVTLILGKELQLQTITLLLEGFTRTAGSEQKTFLSLSTLLFPPSEPAPGDSTKLTQGTHAFPFDFALPPTVTVPYEGGTVIAPLPPTYSTKGFPAFLEYQLTVVVHRGALRVDNTLSTTVVYLPRSRPKPPSPARQLAYQNLTQPPGPEEDPEGWAEVGTELRGRMFGSLEIGVRCTMHLARPLCYARGTPIPFLITFLSPQPQASQALDLLTQPSNLKLTLEQIVTVGPDALRTKNALQSQGNPSNTFGRIVAVARGGVVLPDQPGPGAGAGERRIRGEIPVPRELKPSFTFVRFTLSYKINLLLDAVGFLPEKHTHAVLSQQVAITTDLPRGPRQPPPVPSSGGKRSSVDGPGPGNGLGGPGGTSGDTVNLLLLGNQRYMQHHHAGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC1</accession>
    <name>M5GAC1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_19838</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632179.1">
        <property type="nucleotide sequence ID" value="XM_040771677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC1"/>
    <dbReference type="STRING" id="1858805.M5GAC1"/>
    <dbReference type="GeneID" id="63686739"/>
    <dbReference type="HOGENOM" id="CLU_008891_9_1_1"/>
    <dbReference type="OMA" id="HPAANMI"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="58037" checksum="172D8489B3BDB00A" modified="2013-05-29" version="1">MATAVPGPSPAAKLPARVGGANSSFRDKSKPMEVRLSNMTAAKAIGDAVRTSLGPKGMDKMIQTSGGEVIVTNDGATILSHLAVLHPAAKMLVDLSHAQDIEAGDGTTSVVVLCGSFLNAAEKLLEKGIHPTIIAESFLRASQKAVEYLTEISTPVDMKDRNSLLRAAATSLNSKIVSQYSSILSPIAVSAVTRLITPTSSNVDLRDIRIVKKVGGTIEDTELVEGVVLNQNAITSQSGPTRMEKAKIGLIQFQLSSPKPDMDNQIVVNDYRQMDRILKEERQYILNLCKKIKKAGCNVLLIQKSILRDAVTDMSLHFLAKLKIMVVKDVERDEVEWLAKSLGCKPVADVEQFTEDKLGTADLVEENEHAGAKVIKITGIKGGGKTVSVLCMGANNVVLEESERSLHDALCVVRCLVKKRALIAGGGAPEIHVSRQLAQYAQTLKGMEAYCFTAYAEALEVIPTTLAENAGLNPIAIVTELRNRHALGEVNAGINVRKGLISNILEEDVVQPLLVSTSAIELSTETAALLLKVDDFHLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAN6</accession>
    <name>M5GAN6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632324.1">
        <property type="nucleotide sequence ID" value="XM_040767840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAN6"/>
    <dbReference type="GeneID" id="63682902"/>
    <dbReference type="HOGENOM" id="CLU_1981536_0_0_1"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="13932" checksum="A06724B60A45F944" modified="2013-05-29" version="1">MDSKVNPISNEVAMTYTKPANSTIFENLPAANTSYHSNTSYPTNISYHSNTSYPTNSSYPTNSYPTDTSYPITTYSQSGVVPTIMVTHMGKTKASHPYTVTFPHLDIDAHVCDLEQAAREEDAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAW2</accession>
    <name>M5GAW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF866-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_80541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627970.1">
        <property type="nucleotide sequence ID" value="XM_040776451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAW2"/>
    <dbReference type="STRING" id="1858805.M5GAW2"/>
    <dbReference type="GeneID" id="63691513"/>
    <dbReference type="HOGENOM" id="CLU_114688_0_0_1"/>
    <dbReference type="OMA" id="TAHFVWR"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="175" mass="19439" checksum="0708E4458194CC53" modified="2013-05-29" version="1">MNGSLITSSGTPQRLQLSIKAELENVTDLVPSEADGPFEYHFQVKCNSCNEIHPNLVTVNMHEEHDLTGSRGSAHFVWSCKFCKRESSAKFEPGTKPRPYTADDSPNFAPLITLDCRGLEFTGFSPQGTWECKGTDSGTKFGEIELGEGEWTDYDEKAKLSVSIMEIESKWARAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB18</accession>
    <name>M5GB18_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ADK-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632484.1">
        <property type="nucleotide sequence ID" value="XM_040771766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB18"/>
    <dbReference type="STRING" id="1858805.M5GB18"/>
    <dbReference type="GeneID" id="63686828"/>
    <dbReference type="HOGENOM" id="CLU_032354_0_2_1"/>
    <dbReference type="OMA" id="EQTMPVI"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="265" mass="28421" checksum="A6F451C4DBC0BB70" modified="2013-05-29" version="1">MDQVQQPHVQAETVGVPEAVSHPDSTDPAPAQGKPAFDHKKVLVIFVLGGPGAGKGTQSANLVKDYGFVHLSAGDLLRAEQSRPDSLYGALIQSHIREGTIVPMHVTLHLLEEAMRAALDAHAHPVGEAGGGAGGGGEEGKGWAGGRGWEEGRGRFLIDGFPRKMDQAVRFDKSVCKSGFVLFLSTTESVLLHRLTERSKTSGREDDNPLSISKRFRTFVETSMPVVEAYRRRGKVVELDASPEVGLVYEKIRIAVDAALAVVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB55</accession>
    <name>M5GB55_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably involved in translation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632519.1">
        <property type="nucleotide sequence ID" value="XM_040771777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB55"/>
    <dbReference type="STRING" id="1858805.M5GB55"/>
    <dbReference type="GeneID" id="63686839"/>
    <dbReference type="HOGENOM" id="CLU_082805_3_2_1"/>
    <dbReference type="OMA" id="VENHIHI"/>
    <dbReference type="OrthoDB" id="10248435at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01160">
        <property type="entry name" value="SUI1_MOF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="32"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="113" mass="12585" checksum="1F3DFA4626227FC3" modified="2013-05-29" version="1">MSGPIFNKYDPFAEGDAEAGINETDNTAAEYIHIRIQQRNGRKTLTTLSGLPKQYDPKKLLKAFKKEFACNGTVVTDEEAGEVIQLQGDQRLKIAQFLTVEGIDKNTIKVHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBH6</accession>
    <name>M5GBH6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein NSA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NSA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632639.1">
        <property type="nucleotide sequence ID" value="XM_040771811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBH6"/>
    <dbReference type="STRING" id="1858805.M5GBH6"/>
    <dbReference type="GeneID" id="63686873"/>
    <dbReference type="HOGENOM" id="CLU_033769_1_0_1"/>
    <dbReference type="OMA" id="EEEMWEG"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="31554" checksum="DD70FDDED681CB6C" modified="2013-05-29" version="1">MRLSPSSKTLAYGGDEVNLSVWSIEQALAGKSEASTNDDAKDEKGGKKRKNRELFPGELWRARNEPNDNLDLRQPIQITALAYLSECELVAGNQDGTLRVYDTRSGRRPTAHWKRAMKGSLRSLQSGEVEHQVFAGDAAGTLASFDSRTGRCMYTYRGFASALTALAPIPAFSTTSSAPELLASVGRDRLFRLLSAPKPQADAKKNQEKRGEVLCTEYLPSIPTSVVFAGYGEPVKGSKTGEGEIGRERGEDEEGMEDMGADEEVWEGMQGVGSDEDEAAERRKRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBI0</accession>
    <name>M5GBI0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632644.1">
        <property type="nucleotide sequence ID" value="XM_040767895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBI0"/>
    <dbReference type="STRING" id="1858805.M5GBI0"/>
    <dbReference type="GeneID" id="63682957"/>
    <dbReference type="HOGENOM" id="CLU_511015_0_0_1"/>
    <dbReference type="OMA" id="MWRDLDF"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="521" mass="59245" checksum="10ED7FC7694DF249" modified="2013-05-29" version="1">MVIQYSPEQPKVQGRFSQGFSYLTRRIKGYIRAARLFLRLNKLERTLDMCAMAVERLAVSEKTKRAEVGAIRDEALAAIEERDAGNIASTCHIHRLPYEILSLIFFDAMVDDVSIPITASHVCRRWRETALSNSWLWSTLVLQRRRSELKTAMWMKRSHSRCVDLRIRNDFFLPVDHQEWFKKLVRLVGHNEPARLDLAIGQTLRDMIFDNLPSSIADNLRVLCLHVYLKNPQGKAGFTLPAFTSLRRLELTGYVRIPSELTCRDLEILVIQSIWPCGEPAALFRRLLSDLPKLRVLSLKSPVPASGRDTTPPPEDNEIIALPSLQSVEFIGPGNWLALVKNMDVPALQSLRLDQCVRTRAAELMSTLQPHYSAISELSLCSTSLDEQWLRTHLGMYKNLNRLEISRSAELTNHLVEDLANRSDWPNLQYVNFSHCPLITGSPLLRLVRSHLPPPDDSPDRGDPPDAEGLPNDVRPIKSLIIDGCPKIDHEIAHKLRALVPDFSCVYLTKEASIKRRRADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC52</accession>
    <name>M5GC52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2 17">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_53007</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2 17"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628510.1">
        <property type="nucleotide sequence ID" value="XM_040775146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC52"/>
    <dbReference type="STRING" id="1858805.M5GC52"/>
    <dbReference type="GeneID" id="63690208"/>
    <dbReference type="HOGENOM" id="CLU_013299_7_0_1"/>
    <dbReference type="OMA" id="WSYIAEC"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106414">
        <property type="term" value="F:mRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 17" id="KW-0288">FMN</keyword>
    <keyword evidence="16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 17" id="KW-0520">NAD</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="16 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="34"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="263"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="663"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU291113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJU01613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="685" mass="76499" checksum="FCE45BBBEB828B2D" modified="2013-05-29" version="1">MATSSILAPGTAPVKAEYLISIQVVDVVDDDAAEGVTNPATNDFAVTKRSSDEQPEEEPEHKKQKLSSSQRRRLAKEERKAKRGQNKNRRFTKAHDEIDLCWNAGRGIKCPKEELASCKFSHDLKSYLESKLPDVRIPRKGELLTHPPYVTIPAEPDNDTGRREGIICPEYRELGECKYAFKCRFLADHVEPIPENEEDHLGVGLRILYDANQAEIAREKFQELNRLASPGLLKDLRTKKYPTPKSDEYLAYLATLRDDAPTAGGRGAATANADVESAEQTMGDQSKIPRGQHEHHEEPQDTPDVPMRPVEKLRLHWKNQTYLAPLSTVGNLPFRRLCVDYGASITCAEMGLAASLLNASKAEWSLVRRHPSEGIFGTQLAGNKPGTLVAAAEVISRECPNVDFVDLNCGCPIDLVFKSGAGSALLDQQSKLSKILVGMNRTLGETPLTIKLRTGVKDGRNLAHRLMPRLHSWGVSAVTASWRIHGRSRQQRYSKLADWDYIKTCVDVLRASEADEGLSPIPIFGGGDVYSSQGYWECVEQSGVDGVMVARGALIKPWIFTEIKERREWDISSRERLDIVRQLCEYGLTHWGTDTAGVNTVRRYVCEALSFQHRYIPIGVLERPIGKLNERAPAYHGRDELETLLASTDSNKWVEISSMFLGPPPDQWKFEPKHRSNSTSEEGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC65</accession>
    <name>M5GC65_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_19398</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632979.1">
        <property type="nucleotide sequence ID" value="XM_040771490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC65"/>
    <dbReference type="STRING" id="1858805.M5GC65"/>
    <dbReference type="GeneID" id="63686552"/>
    <dbReference type="HOGENOM" id="CLU_009665_20_0_1"/>
    <dbReference type="OMA" id="YTLMVPQ"/>
    <dbReference type="OrthoDB" id="10016252at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="47777" checksum="7EA127563C6F083B" modified="2013-05-29" version="1">MSLPEQVDVLVLGAGPAGLATACSLLAHGTDKEKIAIVDAKPAHDQAYSRALVVHAKTLEVLERIGCADKVIAAGKPCTSIRFNSLASGPLLQYDTSVLKGKTQYPFVCVIAQSETERVLYARLKEMGGEVVWRKKAVGVREDAEGWKVVLFEDGREVKARYVVGADAAHSVVRQAAGIPFPDPFDHTAHATSLPADIDHPSKADEVFCLADVRVSFPSSPSGKFSLPQEGVNAYISEHGPAMWIPFGDQYRLIGQVLSGEAPREPTIEYMQHMLETRCPAQGVKITELVWSNRFYVKFRLAEKYWEEHVPGTPVQAVGAKTGLMIVGDAAHVHSPMGGQGMNLGIRDSIYLGQAISHALSPTLSVSEARSLLSRWATDRHTAGKNVIALVGQVTFFAANAGGMIGWVRDWMMWLLGWVPGFKARAMWMLSGLGEKGGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCE9</accession>
    <name>M5GCE9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_64932</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630741.1">
        <property type="nucleotide sequence ID" value="XM_040775765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCE9"/>
    <dbReference type="STRING" id="1858805.M5GCE9"/>
    <dbReference type="GeneID" id="63690827"/>
    <dbReference type="HOGENOM" id="CLU_150783_2_0_1"/>
    <dbReference type="OMA" id="KILGWWW"/>
    <dbReference type="OrthoDB" id="3063237at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="13238" checksum="81AACF057A9E79C8" modified="2013-05-29" version="1">MSTSRDRDDFTYEQQNDRRLDELHSKIRSLRSVTTDIYDEAERGNTHLDETINTFASFRTSLSQSANRAARALGLRSNISQFRMILYVVGAIVLLWVLWKIFAWFWWRVPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCL8</accession>
    <name>M5GCL8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit D</fullName>
            <shortName evidence="5">eIF3d</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_73673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit D family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633184.1">
        <property type="nucleotide sequence ID" value="XM_040776018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCL8"/>
    <dbReference type="STRING" id="1858805.M5GCL8"/>
    <dbReference type="GeneID" id="63691080"/>
    <dbReference type="HOGENOM" id="CLU_024521_2_0_1"/>
    <dbReference type="OMA" id="FMDKRDN"/>
    <dbReference type="OrthoDB" id="16538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002191">
        <property type="term" value="P:cap-dependent translational initiation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03003">
        <property type="entry name" value="eIF3d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016281">
        <property type="entry name" value="EIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA gate" evidence="5">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="566"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_03003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="581" mass="63909" checksum="0B14D4E5E1DDC4A1" modified="2013-05-29" version="1">MAAETPSFVLPEMQDNPDGSWGPSTSQIPTQYKDIPYAPYSKSDKIGRFADWNEIEARGTTRDGGAAAGARQTRRYREGPAAYGAGGPSAFSYTHAEDDASFSLVDNKNVPAKRAGSAFNRGGGRGGPMRNQVGQRGQPAQRGGSQQRGGGGYAGGRGGNRDYIGRGGMRLGRRGWRDWEKPGRSRESSIPIGPTWNLLEEIDFSRLAKLRLDVDTSSTIGTYGKLHCYDRTFDRISTKTERALQIGNKIRYYSTTSDDPVIQELAAKDTATVFATDAIISLLMCASRSVYPWDLIINREGNKLFFDKRDGGGFDTISVNENAADPPAEKENKDDINNPADLALEATYVNHNFSFQVVKEDQQLALDHPNPFYGPEETDPLASCGYRYKTFDMSVNDEEDVKLCLRTEADAFLPNSQGGKNDLVSIKTLFEFDSRAQGAGGAPDWRTKLDSQRGAVMATEMKNNSFKLSRWAVQAVLAGAESMKIGFISRASPRDNTRHIILGSATMRPMDFAGQLNMSMANGWGIVRTITDLCMKQPDGKYILVRDPNKPVIRLYAVPENTLTGEDGEEEGEKIDENDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCR7</accession>
    <name>M5GCR7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_2037986_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="121" mass="13392" checksum="9A0A295E0998CB0B" modified="2013-05-29" version="1">MPEEFVSLLTPDTAHTLGDYLQSVVLPEEELEIGKVKVKGMEEARAQDKEKIRLMEEAHAQEKEKMKENTLALVKHAQKLADELSAAKTELEQTKTELEETKAELADVLSVVKTGLAPGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD60</accession>
    <name>M5GD60_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633514.1">
        <property type="nucleotide sequence ID" value="XM_040771619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD60"/>
    <dbReference type="GeneID" id="63686681"/>
    <dbReference type="HOGENOM" id="CLU_1917008_0_0_1"/>
    <dbReference type="OrthoDB" id="10422465at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="132" mass="13650" checksum="3D7669CC258D9A87" modified="2013-05-29" version="1">MTTYVSFEYLTILGSNMVGSLVLQSQDASGVFHYAVLPLAKGDTATNVANTGLVFMDGQDFTKLDNQIVDFKIASGTGGTAPSSCVVSFFGNGNIATLTLTNGQLGWMGASGKCTFFQTPAPPGSAPKPKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD73</accession>
    <name>M5GD73_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_64000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631206.1">
        <property type="nucleotide sequence ID" value="XM_040775747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD73"/>
    <dbReference type="STRING" id="1858805.M5GD73"/>
    <dbReference type="GeneID" id="63690809"/>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_1"/>
    <dbReference type="OMA" id="CDIRGVF"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="336" mass="36265" checksum="CFCDEE2149DE539A" modified="2013-05-29" version="1">MRAIVINSYMHPSDRTVSNDAPEPTLGKNNVLVEVESAALNFFDILQSQGKYQNQPPLPYVLGAELAGTISPHSPIPKGCKLKPGDRVFGYAQGAFAERAACDYRTLFPIPKGMTFDQAAGLYVTYPTSYEGIVNRGETKPGEWVLVHAGAGGVGLVAVQIAKALGAKVIATAGSPPKLEICKSIGGADEVLDYTKSSWQKEVLRITGGKGVDVVYDPVGLIKDSLKCIAWKGRAVVVGFAAGKIEQVPTNLILLKNVSLVGIHWGAYLKNEPGHVPDVWKGIFKLFESGKLIPAVYDPPYMGLDSVPRALVDLENRKTWGKAVVRVREMPERAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDH6</accession>
    <name>M5GDH6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629297.1">
        <property type="nucleotide sequence ID" value="XM_040771126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDH6"/>
    <dbReference type="GeneID" id="63686188"/>
    <dbReference type="HOGENOM" id="CLU_2133425_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="113" mass="13113" checksum="82BE763AF4B1D2BC" modified="2013-05-29" version="1">MSPSDKFKKAMGEDWVKEAGHRIDYKITGDKTGKKEIIVAAQAMFKIRQKLLAKVKQIGIQEMEDDETFTEYGRNWIPSADVIHDKAVKQLSHTLHMGVWISKIDWEHLRMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEG5</accession>
    <name>M5GEG5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">NADPH--hemoprotein reductase</fullName>
            <ecNumber evidence="21">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">DACRYDRAFT_49998</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="21"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630122.1">
        <property type="nucleotide sequence ID" value="XM_040774957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEG5"/>
    <dbReference type="STRING" id="1858805.M5GEG5"/>
    <dbReference type="GeneID" id="63690019"/>
    <dbReference type="HOGENOM" id="CLU_001570_17_3_1"/>
    <dbReference type="OMA" id="QKRYQRD"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06204">
        <property type="entry name" value="CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000100">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000024">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000018">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03212">
        <property type="entry name" value="NCPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="18 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="20" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="15" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="19" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="7 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="24">
        <location>
            <begin position="76"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="25">
        <location>
            <begin position="280"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="26">
        <location>
            <position position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="EJU03228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="752" mass="83436" checksum="BF54FB38078C0E4C" modified="2013-05-29" version="1" fragment="single">SATMASLSTSDLVLVTLGLAIAAIWFLRDQLPFLKSSSSSKPIPNGKSPNGGAKGATGGANPRDFIAKMLDTKKRIVIFYGSQTGTAEEYAIRLAKEAKSRFGLSSLVCDPEEYDFENLDKIPEDCVAFFVMATYGEGEPTDNAVTLMENLEDESFEFSGGEHKLPNLRYVVFGLGNRTYEHYNLIARRVDASLEKMGATRIGKRGEGDDDKSMEEDYLEWKDGMWEEFASVMNVEEGAGSDTADFVVTELEKEFPTEKIYLGELSARALTRTKGIHDAKNPYPAPIKEARELFATGGDRNCIHVEFDIEGSGLTYQHGDHCGVWPTNPDIEVDRLLCVLGLGAPERRTAVINIESLDPTLAKVPFPIPTTYETIFRHYIDISATAGRQALSALAKHAPTPEAAERLTQLATDKALYASVIADGSLKLGEVLQLVSSAKVPDFHVKPTPETITPWKIPFDLIVSLIPRLQPRYYSISSSPKLHPGSIHITVVVLKYQAEKSHHPEKDPKWVFGVGTNYILNLKMAHHGETSVLMSEEGIEDVDLSVPPRYAIEGPRSAYYHEKVYKVPIHVRRSTFRLPTNPKTPVIMIGPGTGVAPFRGFVQERVALAKRAIDKNGPDALKDWGNIWLFYGCRSSTQDFLYAEEWPYYADQLNGKLIIHTAFSRETPRKPDGSKVYVQDLIWQQRGPLTKAILEQKAYIYICGDAKSMAHDVEDQLMQMLGVGKGGTAEVEGAAELKLLKERSRLLLDVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEL7</accession>
    <name>M5GEL7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Postreplication repair E3 ubiquitin-protein ligase RAD18</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Postreplication repair E3 ubiquitin-protein ligase rad18</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 18">RING-type E3 ubiquitin transferase RAD18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">DACRYDRAFT_113608</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RAD18 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632416.1">
        <property type="nucleotide sequence ID" value="XM_040769664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEL7"/>
    <dbReference type="STRING" id="1858805.M5GEL7"/>
    <dbReference type="GeneID" id="63684726"/>
    <dbReference type="HOGENOM" id="CLU_028491_3_0_1"/>
    <dbReference type="OMA" id="IPNTGPR"/>
    <dbReference type="OrthoDB" id="9049620at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097505">
        <property type="term" value="C:Rad6-Rad18 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000172">
        <property type="entry name" value="E3 ubiquitin-protein ligase RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004580">
        <property type="entry name" value="Rad18_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00599">
        <property type="entry name" value="rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="21">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="117"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="214"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00082369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EJU05522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="379" mass="42030" checksum="C7273D6C0C87A092" modified="2013-05-29" version="1">MDLASALAATGSDDVSDPSDFPENFGDLRTLDRTLRCPICKDLFNAPVLLATCGHSFCSLCIREALKEGEKKECPACRIPTQESSIKKNIVLEESVEAYKGARSNVLFLANDAVSRKRRREESANGTDETPRPKRMKRQSSDHVLQSVDEDDERPEESEDSEVEILDSNALVDCPICNHKVLVTRINAHIDAGCPEEQLPSDKGKGKVQWAKLLAGPGGKTGSKFGRRGAGGDTDRSSSPPPRPLAKVSYHTLSNKQVRMLLQTQGLAETGDRKQWEQRHAQWITLYNANLDSSKAKSTDQLKRDLDKWERLRARDEKEKEARMSRVDAKGYEKSQNEHFAKLIVQARASVQGKSNGTLVKGEAESDKPIEISSDVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF20</accession>
    <name>M5GF20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630652.1">
        <property type="nucleotide sequence ID" value="XM_040768165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF20"/>
    <dbReference type="GeneID" id="63683227"/>
    <dbReference type="HOGENOM" id="CLU_1959508_0_0_1"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="128" mass="13633" checksum="961838D9CE65F2BC" modified="2013-05-29" version="1">MLVHLGVISLSEARDARLRTAFGEIDSATLLELPASDDRGRAEEESSLAPKPGPTLTPSQVASLRAASITALDAFASRAHVLKLDLNGAGSGGATAVGLDGWLWSAAKKREDWRACERFVEREPGVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG49</accession>
    <name>M5GG49_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_114190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631762.1">
        <property type="nucleotide sequence ID" value="XM_040769774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG49"/>
    <dbReference type="STRING" id="1858805.M5GG49"/>
    <dbReference type="GeneID" id="63684836"/>
    <dbReference type="HOGENOM" id="CLU_074380_0_0_1"/>
    <dbReference type="OrthoDB" id="4480078at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067737" evidence="2">
        <location>
            <begin position="20"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="34141" checksum="024F3B6BA8913284" modified="2013-05-29" version="1">MSRLVRTILFLSPLPFAGAVVYTYASRKLAKDFPDIPIQQLPEGSFTRRIMEESSARGLARWGREGSGDKDRPLYAAYTDIYQTTIPRSSLESYGARLLEGPLSRKAYETDSFTHAFLNSGLMSRHRRLMSTKRDEREQRGVFEPGQEAMGGTMWVLRSTAGDSSAPTAPSTTAAQRQSALDSLPPDVQPPSSVPSATGAPNGIGSTVFFWRMPASIVSTCDTLASYGYPWRFMLGGYHELLVEEAQAPSAKTEAGAGAGAGADEPMLRVTFTSAHVYERLQGDGKTIPGFGRAMHALFGRALLASAKRRIESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGI2</accession>
    <name>M5GGI2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vanillyl-alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_74770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632427.1">
        <property type="nucleotide sequence ID" value="XM_040776085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGI2"/>
    <dbReference type="STRING" id="1858805.M5GGI2"/>
    <dbReference type="GeneID" id="63691147"/>
    <dbReference type="HOGENOM" id="CLU_024402_0_0_1"/>
    <dbReference type="OMA" id="VFYGTQY"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF114">
        <property type="entry name" value="ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="111"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="67871" checksum="8BAE199AA3AF2A25" modified="2013-05-29" version="1">MTDISSLLVQPPPSWPEKYSGIPARLADIGNQTREKIYAGRSLPRVAPRKQGEELPVLPPDITRERFNEAVAELRKEIGEANVELNDKPLVDGWYMEHPNTHDAFHILEQDDTVSSATIYPGSTEEVQTTVRWANKYLIPIYPISMGRNLGYGGAAPRIRGAMVLDLGKRMNKVLKIDPDNCSCLVEPGVSYFALYEAVQATGYPLWIDTPDLGGGSVLGNAVDRGVGYTPYGDHFGCHCGMEVVLPTGEVVRTGMGALPGKDGEDNPCWQSFQYGYGPYNDGIFTQSNFGIVTKMGFWLMPATEHTSYLITFRDEDQYPQIMQTIRPLAINKVLGNVPQLRHVIQELAVTGKPKSHFYDGEGPIPREVIRKWAKDMPCGDCSWVFYGTVYGPDDFRKGQLDIIRREFGKIEGSRLMLPEKLPQDHYLHSRVSVCSGVPVLRELDWLNWLPNGAHLFFAPIAPTSGEDVKKLFELCRKRHEEYGIDLFPTLCVASRESHVIVNLVYDRSSPASKKAAYDCLRAMISDAAAGGYGEYRTHILFADQVANTYNWGGGALMKLNETLKDALDPNGILAPGRNGIWPERYRGKGYEIFPGDQRTSSLPPHINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGU0</accession>
    <name>M5GGU0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632967.1">
        <property type="nucleotide sequence ID" value="XM_040771485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGU0"/>
    <dbReference type="GeneID" id="63686547"/>
    <dbReference type="HOGENOM" id="CLU_2533581_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="8445" checksum="31B18C86CDC37877" modified="2013-05-29" version="1" fragment="single">MSAGFGTPDYTKRTARATASTSTLTASSSGRGRAPSPPDSAPRVPRALRSNPTHLPPTATSSTPSTLANPANPPSAPLPPAPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGY8</accession>
    <name>M5GGY8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_36621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633207.1">
        <property type="nucleotide sequence ID" value="XM_040774413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGY8"/>
    <dbReference type="GeneID" id="63689475"/>
    <dbReference type="HOGENOM" id="CLU_107208_0_0_1"/>
    <dbReference type="OMA" id="IWIVWCC"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067791" evidence="2">
        <location>
            <begin position="18"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="99" mass="11222" checksum="739957C77FA6A9BB" modified="2013-05-29" version="1" fragment="single">MLALLLLLVNVYDTYKALKASSRLSARAGAHRKRTMKGCMCTWVVWGSWSLLENFGDRTFGWVIPFYGTGKSVLLVLLILGRTRATEPIYLYLLRPAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH01</accession>
    <name>M5GH01_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_92403</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633272.1">
        <property type="nucleotide sequence ID" value="XM_040777069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH01"/>
    <dbReference type="STRING" id="1858805.M5GH01"/>
    <dbReference type="GeneID" id="63692131"/>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OMA" id="FFGVVHY"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="35"/>
            <end position="419"/>
        </location>
    </feature>
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        <location>
            <begin position="201"/>
            <end position="389"/>
        </location>
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        <location>
            <begin position="473"/>
            <end position="537"/>
        </location>
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    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="19">
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            <begin position="580"/>
            <end position="637"/>
        </location>
    </feature>
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        <location>
            <begin position="687"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="1056"/>
            <end position="1136"/>
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            <dbReference type="ARBA" id="ARBA00004604"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00006835"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022771"/>
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            <dbReference type="RuleBase" id="RU363031"/>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF04563"/>
        </source>
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    <evidence type="ECO:0000259" key="18">
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            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJU06378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1209" mass="135059" checksum="26F9BBC93CB6D2DB" modified="2013-05-29" version="1">MPPPGPIPPGYDTINRTNLFRNPPSDGTSVPILHELVAPHIQSFNALFDASGPGETKGLLKLGIEDIGEKVVFERYEDGEPASGARLSIRIKDVIVGRPMVPDRDRVSKERRVFPFEARERLTSYRGRMSIKLAWSVDGGQEEDDTRDCGLLPIMVRSDRCNLKGMSSAELVAHHEEAEEFGGYFLINGNERLIRYLILPRRNHVMSLIRPSYTNRGASYTQYAVTMRCVRPDQTSLTNSLHYLVNGTAMLRFSWRKQEYTIPIMLILKCLMGASDKEVFEGIVMGDYQNTFLLDRVELLLRSFKNYSLPTSQQCLEYLGHKFRVVLNLPDDWEDVHVGSWLINKVILVHLPAAREKFRMLLFMLRKLYSLVSGASCADNPDSPQNQEILLPGSLYAMAIKERLEDALNQIRNMVTLDQRQGVPIDFHNKKYLNRLFKKINFDVGARMANFLATGNLISPTGLDLQQAAGFTVVAEKLNWYRYISHFRCVHRGAFFAELKTTTVRKLLPESWGFVCPVHTPDGAPCGLLNHLSRSCLIVTSTPSVSHIPALLSSLGMTEAFSTHVDGRQNLCVQLDGRVIGWASPTIAGQLAIALRLWKTEAKHNVPLDLEIGLVPESKGGQYPGLFLFSQKARMMRPVKYLPNDRIDHIGSFEQVYMDIAIEPQEIIPNVSTHVELSPTNFLSILANLTPFSNFNQSPRNIYQCQMGKQSMGTPSTALSRRTDNKLYRLQTGQSPVVRPELHNTYGMDHFPNGTNAIVAVISYTGYDMEDAMIINKSAHERGFGHGTIYKTHVLDLTEVRGSQKRSATPNIHFGIGTDIRPDDKRREFVDWDGLPFVGTRLLEGDPMGAHIDDTTGRTVFDKYKGIEVAYVDTVRLLGGDAGDTEAQKMQVTLRIPRPPVIGDKFSSRHGQKGVCSQKWPAIDMPFSESGMQPDVIINPHAFPSRMTIGMFVESMAGKAGALHGLAQDATPFKFSEENTAVDFFGKQLSAAGYNYYGHESMYSGITGQEFAADIYIGVVYYQRLRHMVDDKFQVRTTGPVDPVTRQPVKGRKRAGGIRFGEMERDALIAHGTSFLLQDRLMNCSDYSTAWVCRTCGSLISLGYDDIALGESIMAGRGFSSRKVSGPSGEYCRVCRGREEEKERRERAALDAPQAQAQAQARVDLTFALPNGNVLKKSGDMDVVAVPYVFRYLCAELAAMGIAVSLEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH10</accession>
    <name>M5GH10_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633317.1">
        <property type="nucleotide sequence ID" value="XM_040771574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH10"/>
    <dbReference type="STRING" id="1858805.M5GH10"/>
    <dbReference type="GeneID" id="63686636"/>
    <dbReference type="HOGENOM" id="CLU_136297_0_0_1"/>
    <dbReference type="OMA" id="TAFYERT"/>
    <dbReference type="OrthoDB" id="21617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="143" mass="16592" checksum="298A70A124464EF0" modified="2013-05-29" version="1">MTVQQALPQLYELSGDPGFLSTFKKMKGDQDRLEQKLWDERAMLVRKHEEKLKNARGKAALIRASGSLLQEETKLKQAMEMELTAFYERTVLPEWDDLVERQQDTLEKLYVPTMFRTGVETDRSRQQRIVEMLEGIVAEGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH63</accession>
    <name>M5GH63_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_26748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633582.1">
        <property type="nucleotide sequence ID" value="XM_040774288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH63"/>
    <dbReference type="GeneID" id="63689350"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OMA" id="MHAVIWI"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="208"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="390" mass="41598" checksum="5C05ACACEBC3A8EE" modified="2013-05-29" version="1" fragment="single">DYPEGGRGWWVVIGCAIISAGTLGCDGREYMMQTEIWGVFDNEITRLSWGIFQAWHKDNLFPDVDDAVLSFLGSLPSIPFITGGCVCCFVSMLASTFCKTLWQFFLGQGVLAGIGLGLILPIVLSYPAQWFRRRRGLATGFVIAGCSLAGGATTLVAGQLLNRLALKWTLIIYACLYGILMVAGLCMLKSRAHPGLLLPDLTRPLRRVNKALFTDPVFWSLSLAIMFAVFGYLPPPFYMQQYTCSIIPDVSPVMALVPAAVMNFAAALGRTLVGHVADRVGACNAFIIAVGMAGVVQLLIWNFAYNYATIIVASISFGFFGGTFLSLTSVTATTLYGVNNLATLSGILTLFNTPGNAAGAPIGGAVLSGANNNWHALISYSGASQIVGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNK3</accession>
    <name>M5FNK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_58706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624493.1">
        <property type="nucleotide sequence ID" value="XM_040775513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNK3"/>
    <dbReference type="STRING" id="1858805.M5FNK3"/>
    <dbReference type="GeneID" id="63690575"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OMA" id="AFSMLYN"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="38"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="56775" checksum="586EA6A5FC9C2B96" modified="2013-05-29" version="1">MTVGSLPPSPTEQDPLLPPPSEEPKPLNHPSRADLVWILTGLWSAVFLGALDGTIVATLLTPIGSYFNKAHEASYLGTSYLLSVCCFTPLYGRLADILGRKGAELLALTLFGIGTVLCGIAPSMRFLIIARAVAGMGGGGIMTVSSIVVTDLIPLKHRGLYQGCANILFGAGAGLGGPLGGFLNDRLGWRWAFLIQIPFLVLSYVIVLFKVTIHLPSQAQSLSEKIKRIDYLGSLTLVLAVGCSLLGISLNTSEELPWTHPAVWGLLLAGGTSTVAFVVVEKWVAPQPVMPLRLLVRRNPFFVALTNLLVSISAFSGLYNVPLYFSAVRLTSATESGLHLLPNSVALSIGSLFSGWIMRHTGRYWSLNLFGAFLPILSSTLFSLWTRNTSDFHLWFDIIPSGFGHSSLITSTLIALIASVDRADLAVATGISYLFRTTGQVLGVSLSSAVVQGLLNKYLHERITGPGSKELIERIRHSTALIPTLDPPTQAAAVDSYAQALRVVFILQTVISFLTFLCTLPIQENPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNM2</accession>
    <name>M5FNM2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624578.1">
        <property type="nucleotide sequence ID" value="XM_040775535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNM2"/>
    <dbReference type="STRING" id="1858805.M5FNM2"/>
    <dbReference type="GeneID" id="63690597"/>
    <dbReference type="HOGENOM" id="CLU_125052_0_0_1"/>
    <dbReference type="OMA" id="THGKRDN"/>
    <dbReference type="OrthoDB" id="4087970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019434">
        <property type="entry name" value="DUF2423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219:SF1">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10338">
        <property type="entry name" value="YBL028C_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2423" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11581" checksum="BFF0C07496479ACC" modified="2013-05-29" version="1">MAKGLRSKVKRSFRRAKREDSVYAATHAARVERLHRKLADKIQTDVEGEDGDEPEEEEKISTHGKRDNRKEQWKKAKGFDKASKSRRKMFGGVGGKGKARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNN8</accession>
    <name>M5FNN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General negative regulator of transcription subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_25076</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624638.1">
        <property type="nucleotide sequence ID" value="XM_040773995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNN8"/>
    <dbReference type="STRING" id="1858805.M5FNN8"/>
    <dbReference type="GeneID" id="63689057"/>
    <dbReference type="HOGENOM" id="CLU_013819_3_0_1"/>
    <dbReference type="OMA" id="YKPQTPY"/>
    <dbReference type="OrthoDB" id="293823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1020:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex, subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="14">
        <location>
            <begin position="585"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="180"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="325"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
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            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="325"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="524"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="713" mass="78305" checksum="1E1AB6D6B3A81426" modified="2013-05-29" version="1">MQASTSQTQKEKLEGELKQHIKKLQRLRDQIKTWLASNEIKDKSALLENRKLIETQMERFKACEKEMKTKAFSKEGLSAAQKLDPREKEKLEASQWLSAMVEDLQRQIEQTEAEIEALSGGAKKKKTGGDDRQKELDDLNTRRQWHLGRMEIVLRLLENGTLPADKVQALKEDISYFVQSNTEEDFEEDDGIYDDLNLHEEEEKLGMGQDDLQSSHDTESMAEEPTAAQRTPIRDNGMPRKSTVDEESSTGSNKKEESSPTAKKSILLRRMTLEKSEAPKLPPAPNFTAQPMSAAVKSGVPIATAPKPAIPPLPPIRYSAAVAASVPPATPASTAPSVSSAVPPAASVASKAPEPSETSEPSPALPPSPSLTQPSLSAPSPVPSSIPPSQLSRATPPPMSTASYLSSPVSMQIGMSPVQQLRDVDGATDSPSSALSQVPSAAPAPAQVNGPSPLSATNGTSAAQPSLPTSNAAVASPAPPSYVPPQLPLPIPSDRSSPRPPSVQPQFGASTKMNETAARQAPVSRPTSAAAPQQAPPARTTSAASSRYPASLSDLVSSFEAAKGKSLRRMANPEQITRVLDHGFASMPQPKDSERPSYYKPRNTFRTPEYYPQNPPPVLSEPRIYSSADVETLFFAFYYKPGTYQQYLAAQELKRQSWRFHKQYLTWFQRHQEPQAITDEYEQGVYVYFDWENSWCQRKKSDFRFEYRYLSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP44</accession>
    <name>M5FP44_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemimethylated DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625093.1">
        <property type="nucleotide sequence ID" value="XM_040770691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP44"/>
    <dbReference type="STRING" id="1858805.M5FP44"/>
    <dbReference type="GeneID" id="63685753"/>
    <dbReference type="HOGENOM" id="CLU_020266_1_0_1"/>
    <dbReference type="OMA" id="PCGFLFH"/>
    <dbReference type="OrthoDB" id="28868at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.390">
        <property type="entry name" value="Hemimethylated DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02097">
        <property type="entry name" value="yccV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350:SF27">
        <property type="entry name" value="HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350">
        <property type="entry name" value="SI:DKEY-261L7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemimethylated DNA-binding" evidence="2">
        <location>
            <begin position="507"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="700" mass="79340" checksum="45A2943CD2A51F34" modified="2013-05-29" version="1">MAHLALPIEIYEHIFQLLVPSPTEDADVFALAQCAATSSFMRSIATANLVWMAHYQVRYLASNPIKETERIAACNGSYFKLYRMRRLLDRRALDTLQDAIYRKQGRCTTGRLFAYDLGIDVHDVLRTQSVMRWPRNIAKTDEPALDSLTLDWIARPYWAREAMTVITKLEALRLWRKVVVQPQYVSFAEGFAAFSGFRGVSPQQVIKDLNALCKRCESHLRAKGVSLESGLEDYDVVNISNEICLWMREEGFRLAAGVDYHRMENHFLDCVITTHRDTLPLSLVVIFVSLARHLGVEAHPVGFPQHVHVLVRGHVPSTSRFFFPGFPERGEEYIHLDIAKSDERLVLPRSHLISILEGMGVTNSVQQGQLLQPANVRDMCGRAGSNVQHSFHTELEALANPNGPRYSYIRDCVHAAMSAFVMLSTPGTRGATTMLMHMLNYVEDAHRLDWCLMQYEVFPNDVGHHTNDVGAVQVRDQLIHMYELQETNELQAKRDADSMPLAVDGTNVEFHVGTLMRHAKFAYIGVIADWNTKCHQPEQWMREMGVDMLSRGRNQPFYTVFAMDGTVRYVAEENVEVHTLPSDTWGTIRELLMNAKNIEMHFDRAEVGKNGVGKFIMGADLRREFPGDVLLAQKELGELQLFILAKTEQSVVVPPGVTHPTAPWKPPWPVPPWPPIPPPPKPPVSEPVPPLPYPESPWFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPI6</accession>
    <name>M5FPI6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_60408</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795937">
        <property type="protein sequence ID" value="EJT96464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623362.1">
        <property type="nucleotide sequence ID" value="XM_040775634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPI6"/>
    <dbReference type="STRING" id="1858805.M5FPI6"/>
    <dbReference type="GeneID" id="63690696"/>
    <dbReference type="HOGENOM" id="CLU_064194_3_1_1"/>
    <dbReference type="OMA" id="KFEWTVG"/>
    <dbReference type="OrthoDB" id="10261807at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT96464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="29851" checksum="B945CC2162A40A35" modified="2013-05-29" version="1">MSSPSALEIVSRPSTERGHADHGWLKTFHTFSFANYYDPSHSGFGSLRVLNEDRVLPGTGFGTHPHSEFEIFSYVVSGELEHRDSMRNVEVLKRGDVQLTSAGTGIRHSEKTFGASPVHFLQIWAKPRVSRLVPKYFTRHFSDEEKTDKWVKVVAPVEAEGVLDKREGDGPAPVQSGVTMYATLLSEGNSLAHRLPLDGQGKTRKVYVHVVQTSGYNDGSSSGARVKLSGEGKELELREGDGAYIAGLPERELILENVGEGRAEIVLFDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPL5</accession>
    <name>M5FPL5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795904">
        <property type="protein sequence ID" value="EJT96504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623402.1">
        <property type="nucleotide sequence ID" value="XM_040774264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPL5"/>
    <dbReference type="GeneID" id="63689326"/>
    <dbReference type="HOGENOM" id="CLU_2729096_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="72" mass="7834" checksum="2740F9B805C4FB93" modified="2013-05-29" version="1" fragment="single">MQQTTHRNPSVGGAGFNANAGPQYPHPNVSQYMPPLGVYEAPPQQYGTHQTYRNTPNDGFNANPGPQYPHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ20</accession>
    <name>M5FQ20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624376.1">
        <property type="nucleotide sequence ID" value="XM_040770819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ20"/>
    <dbReference type="STRING" id="1858805.M5FQ20"/>
    <dbReference type="GeneID" id="63685881"/>
    <dbReference type="HOGENOM" id="CLU_065316_0_0_1"/>
    <dbReference type="OrthoDB" id="411584at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35936:SF17">
        <property type="entry name" value="ARGININE-BINDING EXTRACELLULAR PROTEIN ARTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35936">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Solute-binding protein family 3/N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="243" mass="25709" checksum="5FFC24296B900ED3" modified="2013-05-29" version="1">MANLTAIAKDLAPTGTLRASINIGNPILAQGTLDVPTGPTVDISHEVARRLGLPLQLIAFNAARKSFEAMNEGRADICYLAIEPVRAAEVSFTAPYVLIEGVFAVPVDSPIKTVEDADKPGVRIGVNEGSAYHLYLSRTLKHATCVFGDGDGQDVFRANKLEAAAGVRGPVLAYVAKNPDLRVIPERFMVIQQAVGIKKGKSPETVQWLSDLVGELRASGFVAQALERAGQDPALAAPPDATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ31</accession>
    <name>M5FQ31_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Multifunctional tryptophan biosynthesis protein</fullName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
            <ecNumber evidence="7">4.1.3.27</ecNumber>
            <ecNumber evidence="9">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">DACRYDRAFT_25522</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EC" id="4.1.3.27" evidence="7"/>
    <dbReference type="EC" id="5.3.1.24" evidence="9"/>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623582.1">
        <property type="nucleotide sequence ID" value="XM_040774196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ31"/>
    <dbReference type="STRING" id="1858805.M5FQ31"/>
    <dbReference type="GeneID" id="63689258"/>
    <dbReference type="HOGENOM" id="CLU_007713_2_0_1"/>
    <dbReference type="OMA" id="EPIEWAN"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000136">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854:SF2">
        <property type="entry name" value="INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="14" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="17" id="KW-0456">Lyase</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="21">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="22">
        <location>
            <begin position="156"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="23">
        <location>
            <begin position="509"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="597"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="738"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="738"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00018819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EJT96684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="781" mass="82227" checksum="0B06A60320E678F1" modified="2013-05-29" version="1">MGLQCLVDAYGGDISYAGEIVHGKASPVRHDGLGIFRGVPQDILATRYHSLAATLPTFPKELAITATTSDSGVVMGVRHRLYAVEAVQYHPESILSQDGHAVLRNFLAYSGGSWAQNPDSGVIPSAPAPATAQGQNGFDPNPENAAKKGLPSILLKIQTQRLLDIDLAKKTPGTTPQDLATLYALHLAPPLIPVLSRMRAGTKPAIMAEIKRASPSKGHIAVSTCAPAQALAYALAGASVISVLTEPKWFLGSLQDMRLVREAVAHLPNRPAILRKDFILDEYQILEARLAGADLVLLIVAMLSQERLSALYAYSKSLGMEPLVEVNNATEMERGLALNAKLIGVNNRNLHNFDVDMGTTTRLADMLRGREDVLLCALSGISSRKDVEVYIQQGVHAVLVGESLMRAQDPKGFIRHLLGDPQTQTNDTPSPQPLVKICGIRTPEEALLAAHAGADMLGLNFVPQSKRSIDLLTAAVIARTILPLRLGPSPAPLAHDSEEKSDNQITTGTPWFQHTTSHIASLPRPLLVGLFQDAPLSIILHTLAHVPLDLVQLHGSEPAGMAHFIPVPVIKAYHVGPLGEGTEHVGRPGQESIVLLDTAPRPHPSTSPSSAGAGAPVGAAAAPAGGTGEAFDWSIAAEVGKRSEPLEGRPMPIILAGGLKPENVRQAVRRVRPWAVDVASGVEVEGRKDEAVMRAFVSAAKGAWEELPASVEPATVAPVQEGVLIDVGTEVIGQPVGATTAAPPVPSPGTSGIATPAAANGSVPPLPAVSAKRGLVRPEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ38</accession>
    <name>M5FQ38_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_119916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ38"/>
    <dbReference type="GeneID" id="63685953"/>
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    <dbReference type="OrthoDB" id="3353485at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="44720" checksum="36AB1ED11FDC2ED9" modified="2013-05-29" version="1">MSRPGGHMAPITSRRMLDELWRLVLEELVEENPTQLTIAPLLLVCKAWKTCGQSLLYRHLCFSGIRQLRAFYEHLFFHATEGRYPGLYTQTFTLWTRGLVLQELSHYVPRMLGYLHNIRAFHAQELDICSSILEPLDVVAKRTLCELSLTLCSAEADGAINLAIVSRFTGLKKLQLRMNWGADSTVFAIGRAPGFRMPRLVSLALSSPRVPPVHEFLAFLPRCELPALTSLDLDFPHLTADGTASLQPVFEKLGSQLRHLSYNVPEAARLPQTALVLSPNLELIEFKTAAPSIDLIHILPATIQQINIPVDFSFSEGPAGVVRFLNDWLAENPADCSLRRVQLTMKGLQRFDWRTVGLVSPVFAGQLMTSAILLGARGVHIIDGFKNTLIMVAASQLTGLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQF9</accession>
    <name>M5FQF9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_97392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623862.1">
        <property type="nucleotide sequence ID" value="XM_040777450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQF9"/>
    <dbReference type="STRING" id="1858805.M5FQF9"/>
    <dbReference type="GeneID" id="63692512"/>
    <dbReference type="HOGENOM" id="CLU_003182_10_2_1"/>
    <dbReference type="OMA" id="TGPMSVT"/>
    <dbReference type="OrthoDB" id="427213at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="469"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="603" mass="66492" checksum="137B449425B9267A" modified="2013-05-29" version="1">MRYYVPATKWMVEYKLESLWGDTVAAITVAAVIIPLSLSYASSLAHVDPFSGLFAAAIQPLVYSLLGSCAHLSVGPEGSLSLLVGQAIQRVWHDDPHSGDDFAEIAAEVATMITFQVGAISLLLGLLRLGFIDVVLSRSLLRGFVTAVSLVIVIEQLVPMLGLQSIYANVDLHTALDKLIFLLQHLGSSHIPTTILSLCSMAFLILTRTVKTHYKKRFTPLMYLPEILICVVVTTILCGTLDWQSRGIEVLGPVSISQRKSFLALPLQRKNLRFFKQTFPTAIFCSIIGFIDSVVAAKQNAQRFRYSVSPNRELTALGAGNVVASFVPSTLPAYGAITRSRLAADTGGKTPMTSLILSVIVLLSIRFLLPALYFLPKAVLACIICLVVYTIIAEMPEDILFYWKMSAWSDMILMLLTFFLTLVWSVEVGIGIPFALTILLVIRQSSQQRIKIMAREPGTTHYVPIDEDFPMELEDTSGVLVVRICENLNFVNTGSMKERLRRLELYGNSKHHPSDAPVRAEAVAVVFQLADVEEMDASAVQIFRELAETYSSRGVCVCFARVRPAQMSALRKAGVVLFLGEDHFFPTTAAAVGFVERERHGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP4</accession>
    <name>M5FQP4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624771.1">
        <property type="nucleotide sequence ID" value="XM_040769225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQP4"/>
    <dbReference type="STRING" id="1858805.M5FQP4"/>
    <dbReference type="GeneID" id="63684287"/>
    <dbReference type="HOGENOM" id="CLU_556698_0_0_1"/>
    <dbReference type="OrthoDB" id="3222238at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="57938" checksum="7F95B4958F4F15DE" modified="2013-05-29" version="1">MSIFQQPEERVGPAFKIPEVLDSICVYLDDPDLVKMACASKSFTDVCMKILWESPVFDGSPLVRMSRLFPEDVGKHLGQGLRPGARIPPGAFERFDYYAGLIRSLHLWHPEEEAAIARVLTDSRPGLWLFPGLVDLDLGASTETLRTAPFYFSPSILSLRLNHWDLNGMRELSATEDVKRSLLRACAFPKLEKLDLADALYTRLENDGDLVEAFTDIARRVYDCRALSFLTVPGVFAALAGNMRLHTVYLNLVDKQRHHEHLHVILSRLRDDFIALRKLGLACSAKHAVRMLQETRRAYEHIDLQVDTPIEGVQLHEIAVALFLSSNGLRYFRLLTSAHLFCDVDPPLRLSEAFQPLQSCRMLKHFELALMFDETHMMRDVELVGFFRLWPELRVFVLRCDTDGDRAVGDDDEGSYSGSESLRENGITLFPLTAAARHCPRLHTLSLPFVQTSEIPSTEGIERVDGSVAIRLNKSHVHNHQEVGEFMARLWRETYLSLGGCVHLEGMTMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQQ6</accession>
    <name>M5FQQ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626163.1">
        <property type="nucleotide sequence ID" value="XM_040773428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQQ6"/>
    <dbReference type="STRING" id="1858805.M5FQQ6"/>
    <dbReference type="GeneID" id="63688490"/>
    <dbReference type="HOGENOM" id="CLU_066046_1_0_1"/>
    <dbReference type="OMA" id="PRCTEYV"/>
    <dbReference type="OrthoDB" id="10006218at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="113"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="38636" checksum="9D6113F51856836E" modified="2013-05-29" version="1">MSALNQLKHLLWRIQSSQPSLTSYSPRSLAAFALTAFVILILIGHWVLSGPRGWFNGHGYDRPITVEERLQYSEWIYQGMVRDRIKFVNDLGGVNSVNPWPSGSGWRAEYTLWDFFLPSFECPHMTERIGKMGDGGKWVCGMDIIGRKPSPVLYSFGVSTDSSFEAAVLERFPGAQVYGYDYSVNSFGPQIVDSRELQGRAHFHKWAIGPKDQHGPDYDPSFQVYTVETLMRLNGHSFIDILKVDIEGSEFEVLAGICQHYLAQGKPLPFGQLQVEIHAWDSKQSFADFLAWWELLERAGLRAFRTEPNLVYVNLMGAKPNLAEYSFINIRGHHEIVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQW5</accession>
    <name>M5FQW5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_71699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624886.1">
        <property type="nucleotide sequence ID" value="XM_040775952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQW5"/>
    <dbReference type="STRING" id="1858805.M5FQW5"/>
    <dbReference type="GeneID" id="63691014"/>
    <dbReference type="HOGENOM" id="CLU_525401_0_0_1"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="519" mass="58192" checksum="F98F0F3ECBBA7EE1" modified="2013-05-29" version="1" fragment="single">MACFVFLLQPDVGREKHIVTTLVRDLAGRDMDIADAVAEKLSYDVSLRTTPDIERQFRKLVIEQCKEWSRSEPAVFVVDALDEGLDEGLLHLLTRQVKDLPSFFRVVITSRPLAEISSAFEHVENITRKSLDTMDMQSQEDVQTYLDERLAAVAIKRRLGQPWPSRPAAKALLHQSEGLFQWAFTVTEYLGKCMNPNRQLDLIISLQRIPSVASRMDQLYATVLDGTGGTDDEDFVNAYQMFMGSILAAKEPLTLSAMRLLHGNTDVDPLELLERMGSFVVGFDSEDEPIRILHLSLREYLVDRATPPYRLSQVHNSEHLAFLCVRVIKDHLSKTCRILKPKQRSHAQSLTCPIPRESMSDGLTYAISFWTHHLPDVRDPTPEFMSALELLLDEHLQDLVSVTIALDEYKGFSDVRRWLQNHGPAGKQALLRISDDHWVFLFTWASAVLMNNFRVEEAWAAADDSVAAAIGIADGGTGNASLAEAAHTTVPVGATVSFRMAEVAKFALQNIRKASSTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR32</accession>
    <name>M5FR32_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_119439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624212.1">
        <property type="nucleotide sequence ID" value="XM_040770787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR32"/>
    <dbReference type="STRING" id="1858805.M5FR32"/>
    <dbReference type="GeneID" id="63685849"/>
    <dbReference type="HOGENOM" id="CLU_048953_0_1_1"/>
    <dbReference type="OMA" id="KYSEDNW"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="306" mass="34498" checksum="D87C4EF618C15051" modified="2013-05-29" version="1">MSPVSVDDSKLTYLTPSQVSKFYDDGYLVIPQFLDQDEVDKLMKRTQDLLDSFDLEGHPLTKFTTGESEDESKHVGDDYFLNSGDKIRFFMEEDAVGKDGKLNRPKNRAVNKIGHGLYECDAVFREVSPHNPKLKAVARDLKFHKDPAILQSMVICKQPEIGGKVPEHNDSTFLYTDPPSAIGFWFALEACTPTNGALSFLPGSHKTTPISKRFVRLPTGGTGFEQLQEENAPTDDAEYVLETCDAGTLVLIHGSVLHKSEKNLSQATRYAYTFHMIESEPYAKYDEKNWLQPTQEMPFTKLFAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRZ6</accession>
    <name>M5FRZ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_91048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625441.1">
        <property type="nucleotide sequence ID" value="XM_040776992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRZ6"/>
    <dbReference type="STRING" id="1858805.M5FRZ6"/>
    <dbReference type="GeneID" id="63692054"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="VDQYSAD"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29331" checksum="4E31C7B0F076D436" modified="2013-05-29" version="1">MACQVWFITGTSTGFGRTMAEHVLKNGNIVIATLQKPNMLADLTRQYDKTRLLVLKLDVAVSSDILPAFQKAIDAFGRIDVVFNNPGSTLLGSSENTPEGAARKIFETNYWAAVNVSREAIRVFRDVNPPGAGGRLLQKLSVAGLGPLVLFGHYTASKHALEGFTKMLAMELEPYWNIKITLIEPDFFQTQIIQQANVFPVYQNYNNETTAIFRSALAIGECPDDADEEVATIYEVAHLPNPPLHFSLGLDVVQVMRTVGALLDCDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSD4</accession>
    <name>M5FSD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_42349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627218.1">
        <property type="nucleotide sequence ID" value="XM_040774516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSD4"/>
    <dbReference type="STRING" id="1858805.M5FSD4"/>
    <dbReference type="GeneID" id="63689578"/>
    <dbReference type="HOGENOM" id="CLU_000384_22_9_1"/>
    <dbReference type="OMA" id="HECILHA"/>
    <dbReference type="OrthoDB" id="8023605at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10998" checksum="703163677246FAA1" modified="2013-05-29" version="1" fragment="single">LALMHECILHAREVSVQRFRVKYHSQIRDYDFQPGALVLLRNSRNDGDLRDKMQPWYLGPYVMVCHNKRGSYIISELDGSIGRYAIAAFRLLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSV5</accession>
    <name>M5FSV5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_56785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625936.1">
        <property type="nucleotide sequence ID" value="XM_040775395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSV5"/>
    <dbReference type="STRING" id="1858805.M5FSV5"/>
    <dbReference type="GeneID" id="63690457"/>
    <dbReference type="HOGENOM" id="CLU_032232_0_0_1"/>
    <dbReference type="OMA" id="GWESGNE"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="37273" checksum="AADB5D4A5AFA98A2" modified="2013-05-29" version="1">MHKRDDFVTRSGSKLFLDGFEFRPVGPNIYWLGLDENVVPNLSYPSQTRVWEMMGIASAMGANAIRAHTLGISFGNSLSVVTGPNTYNDGAYQAIDFAIMAARVYGLKLIIPLYNWYHGGKYQFVGWAGHTWSGTGADITPPDVGGFFYNDTTCIQLFMDYIQHHLTHVNQYTGIALKDDPTIMIWETGNELSVYQRDDGPPPNAWTQQICALIKSLAPNHLCMDGTFGIFPNSGQLSNSNVDALTDHFYPASVSRLQTGASYTMNEAGKVYIAGEWDWTGQFGGDDINSFMNAVQNIDGTGDFFWSLFGHDSDCCTLVTHNDGYTMYYPGTTSGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT75</accession>
    <name>M5FT75_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SAPS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_81013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627698.1">
        <property type="nucleotide sequence ID" value="XM_040776487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT75"/>
    <dbReference type="STRING" id="1858805.M5FT75"/>
    <dbReference type="GeneID" id="63691549"/>
    <dbReference type="HOGENOM" id="CLU_003676_1_1_1"/>
    <dbReference type="OMA" id="HAYIACE"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="275"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="497"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="564"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="770"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="773"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="904" mass="99515" checksum="AB1F85A3DAEBCDAB" modified="2013-05-29" version="1">MYWRFGFHSTSSIDTLLEKPDVPVESILEDEDLLQECKSQNARLVQYLQRPDVLRTLFGYVTGDIDVEPRSSYKYPYLAAEVLCSDIWSIVETCLEHSDELLTPFWDTVLSKTTDDLLSNPVMPARFTKINSVFLAKKPAEMLQFIKSVPDVVTKLLAQVEIPAVVDLLFRIVKSDGQIEGAGAVDWLSTEGFVPLLMNLLSPYERPEIHVAVSELLKDIISISCPAPGNVSMTGGMDDAAQDVSVSNRLVRELAAERTVIKLVGFMLGDTEDHANGETSRLWKQSDEPAESFSRSSREENAPLAPPPERAASALVHGTSVAIELIRKNHSDYYEPVLFHTLRNRLIAVQQHQALTTPNTMASHVGSEDRESLETALASLAEEVGIVHLGHLLNAVCDRLDEFQALLRQPRTSVSCSRPHIIHSFGSESCQTAPLETTMGLVVPLTFERLRICELYAELYHTSNMALLNRLPGDGPSYDSEGRLLGGLAGLGELARVSASGPSDASHSDRDEKESELHAARELPVSTSSMDTSSISVDEDMLDEALENAPVDSDLAEAAITDPPVTSIQHSSPRGVDPFQDPDDSGAPLEHDTEETDLARERACSGDRLKQQYLELGILETLLSLFFDYPWNNFLHLVVYDVVHQVLTGRVEEGYNRLLTIHLLKDARLIERILQYQPQGEQSQSENNVRGGFSGHLMLLADDVIQAYDEFSKSMKVCLDTVVPQPEWDVFVARHRLAKEQEKKILGGIRPAAANRRTALFSAQVDEVGGTGATTSSNVTSLAPPTSSNSLKTPPLSSSRQVTAFDQDERDSVLVASPDEEDDDEWGSFASTTQGDAILSFDEEEEDTLAFTPAPSISERVLTIADLNSSFHADIEAKGSTAIFEQWPPDNEAEEGMGDIMNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTL6</accession>
    <name>M5FTL6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_73027</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623479.1">
        <property type="nucleotide sequence ID" value="XM_040775988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTL6"/>
    <dbReference type="STRING" id="1858805.M5FTL6"/>
    <dbReference type="GeneID" id="63691050"/>
    <dbReference type="HOGENOM" id="CLU_015515_1_0_1"/>
    <dbReference type="OMA" id="HFVNFQR"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000158">
        <property type="entry name" value="Glycyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="224"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT96581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="661" mass="74081" checksum="78FDB7BF488B0D82" modified="2013-05-29" version="1">MATSVPTTSVKKDAHPFNRETLEGLLAKRFFYTRAFEIYGGVAGLYDYGPPGSALQANIIEFWRKHFIIEEEMLELDTTIMTVSDVLKTSGHVDKFTDWMVKDVKTGDVLRADHLVEGVLEARLKGDKEARGLKAQVAPVTDADKKKKPKKNMKSVAVQLPDDVVALYESTLAQIDNYTGAQLGELIRTQSILNPDTGNEVGEPVEFNLMFESSIGPTGQIKGYLRPETAQGHFVNFSRLLEFNYGRVPFASAQIGRSFRNEISPRAGLLRVREFTMAEIEHFVDPLDKRHARFDEAKDIVVGFLPKGVQESGRTEIIKMTIGEAVAQKIVDNETLGYFLGRIYLFLTRIGINPARLRFRQHMKNEMAHYAADCWDAEIHTSYGWIECVGCADRSAYDLSVHSKKTGQKLVVRQALPDPIIVERWTAEIEKKLFGPRFKKDAKAVEDAIMALDEPRLVLLNGELVKGPTKLKLDDGREFEITSDLLTIQKKTFKETVREFTPNVIEPSFGLGRILYSLLEHVFWCRESDEARGVLSLPSVVAPIKALIVPISSNEVFTPFIRQISAQLRKAGVACRVDDSSASIGKRYSRNDELGTPFGITVDFATVQNGTLTLRERDTTDQRIGKTEEVISLVIDLVDGRIDWAQACEKLPAYTGVQDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTZ8</accession>
    <name>M5FTZ8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626531.1">
        <property type="nucleotide sequence ID" value="XM_040770465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTZ8"/>
    <dbReference type="STRING" id="1858805.M5FTZ8"/>
    <dbReference type="GeneID" id="63685527"/>
    <dbReference type="HOGENOM" id="CLU_1304816_0_0_1"/>
    <dbReference type="OrthoDB" id="3365400at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="211" mass="23068" checksum="28F866BDA7DDA0DA" modified="2013-05-29" version="1">MSLPSNSVSPSPPTASFPPYQTRPSLFSPIIIIPVSVTPSHTADQAAAFNEFVPLDTPPPRYNDRFRRPSRRNLRQALERLETTYGPWESLLNLPLTASASTSASSSPESSSLLSATASSSSTPMFAPPRPLPSYSDAYLLPPSYPFPSPDPSASLSSVVPGWDKHPVPDELPPPFGGKKKRRSLLDILMPGLGRHRIFGRPRRERQTEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUB0</accession>
    <name>M5FUB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628198.1">
        <property type="nucleotide sequence ID" value="XM_040768550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUB0"/>
    <dbReference type="STRING" id="1858805.M5FUB0"/>
    <dbReference type="GeneID" id="63683612"/>
    <dbReference type="HOGENOM" id="CLU_080764_0_0_1"/>
    <dbReference type="OMA" id="MPGRIAT"/>
    <dbReference type="OrthoDB" id="5397701at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="205" mass="22550" checksum="32303114426A5293" modified="2013-05-29" version="1">MFLLPQLRSLLRPTLFKRHFHPSAAALTTLRDPARPSLYYHLLPSPTTQHFALSFLPSPPASARSKTIIGYLPALQSTRTTSDPVDAYDSGSQAEGEGELGLNDFRENAPFLQLLHEVLKRSVAEDAAWAGEALARREGFMPISGASVSASPSIVPESYEPMPTYRVCTTDGVVTLSEGLESRLVEELERVDLEEHEMLKADEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUJ4</accession>
    <name>M5FUJ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_116587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628318.1">
        <property type="nucleotide sequence ID" value="XM_040770233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUJ4"/>
    <dbReference type="GeneID" id="63685295"/>
    <dbReference type="HOGENOM" id="CLU_088628_0_0_1"/>
    <dbReference type="OrthoDB" id="3379144at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="231" mass="26165" checksum="3CC0321ACA151C7C" modified="2013-05-29" version="1">MVFIYQNRLQTVITGPVYLYRPGDSDFVPKGVGYWNGLNSSDPQNTITCPDIHPKGYGYRVVIVPDRDSPARKPQHSLTFPIVSQSWLTTGYDKVYLFEPTSVHDDTKWSSTGKQLLAWQDTNHTFDEFDVWLHKSADVTWGPKLLTHVVNASCPLAPATGSCSAIEYYFEYHKQLPKGEGWQLVFQQGRQEKRVFAVSGLIEIVDSPVTTNTFPYSWTPIRTIASEATTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV15</accession>
    <name>M5FV15_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_95150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628508.1">
        <property type="nucleotide sequence ID" value="XM_040777278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV15"/>
    <dbReference type="STRING" id="1858805.M5FV15"/>
    <dbReference type="GeneID" id="63692340"/>
    <dbReference type="HOGENOM" id="CLU_022138_3_1_1"/>
    <dbReference type="OMA" id="FQMRNTH"/>
    <dbReference type="OrthoDB" id="1905920at2759"/>
    <dbReference type="UniPathway" id="UPA00896">
        <property type="reaction ID" value="UER00863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000201">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="310" mass="33666" checksum="EDA4D5707B112FAC" modified="2013-05-29" version="1">MPTPFVKIVEVGPRDGLQNEPFPVAVQTKVELINRLSATGLKSIESGSFVSPKWIPQMAGTSEVLRLIDHKHGTSYPVLVPNMKGLEGLEVLLRENPRQPVSEEIAIFTAASETFNKRNINCTIAESLDRFVPVVERAIELGLRVRGYVSTAVVCPYEGYIEPEKVRDVTIKLLEMGCYEVSLGDTIGAATPRTMERLLDVVMAAVPIEMLAAHNHDTYAMAIANVLTALKMGIRTVDSSVAGLGGCPFAPGATGNVATEDLVYALREEGYETGVDLNKLSTTGQWISSILGRDNGSRVGKAWLARKKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV62</accession>
    <name>M5FV62_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_97306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624079.1">
        <property type="nucleotide sequence ID" value="XM_040777440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV62"/>
    <dbReference type="STRING" id="1858805.M5FV62"/>
    <dbReference type="GeneID" id="63692502"/>
    <dbReference type="HOGENOM" id="CLU_760818_0_0_1"/>
    <dbReference type="OrthoDB" id="10532085at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="364" mass="39866" checksum="B3095D8168F040B7" modified="2013-05-29" version="1">MTIMGPMCDHCQTQSTPLWRTRRVTGEVLCNACSQYEITHEGAHRPAELCQRGQKRRSRKSVSGTARASLDGNTIVSASASARTSIDGTTARSSPEDVRSMSVSTLTPTTSVASTGISAYPTEGNRTPARVRSRKRPRAQEEATMVKRAKEKAEDVFIKLELETGTGTMVGLPPISREIGLRKRAEWKGLDMLGYAPTGMPDLQQDEPPEPERKRKKSTFHVSRNKQFIMPKAAFGFLGTPYSSSSKLPTWLELVFSKADVSPLDTAYRIWPQEATQDSREAVDLLTSSSHTTRMLSSGSPHLLDAPPSPTWSISTIHGTDTEKMEGRCLLDTERATGDVARARGDKRLGRGGQEGGDGRSERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV81</accession>
    <name>M5FV81_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_102582</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624104.1">
        <property type="nucleotide sequence ID" value="XM_040767644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV81"/>
    <dbReference type="STRING" id="1858805.M5FV81"/>
    <dbReference type="GeneID" id="63682706"/>
    <dbReference type="HOGENOM" id="CLU_512894_0_0_1"/>
    <dbReference type="OMA" id="PLGFGCY"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="12">
        <location>
            <begin position="178"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="71"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="468"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT97206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="58636" checksum="39A2AE19EDF2FE3D" modified="2013-05-29" version="1">MASPVLCRASVPLRGMMSVGGQRSLYLARPPPAFSLRTLPLVPPLISMRRQRPAVGIRAFSLWPFTSSPPAPLPPSNAAHSPESTSAAPTTPENIPNTPSPPDPVELSSAASTPPVDLPSHSTIPDLSETVPTIDPSSWPVMHFGDLASLDLGFSWTPASWAREGIELVSAGTGLPMWTSIILLTILVRFALFPLAVKSMRNSTALAKIQPEITRLQTQIKNSAKKGDYVKANLDQREIVALMSANKVKLGSTFVYPLAQITAGIGLFFGLRSMCLKPVPQMLEGGTAWFTNLCAEAHIFGQHAVWWAPWTWIGLDTLWILPMAATAVMYVNSRWGGDIGLQSQQVQNMRSFASNMVVLFAFITIVQPQAVCLYFLTNNAFLLLQSQLLANPTIRNYFAIPPPAPPSLDPPKPPFRWLEAPGKIRNWFEEQAKAAAEQERERVAQVVAREQRRTAQQPVKWFDLENERHAQAQSHKPKDAKHPPDRVAASNTLHEVEKQREKKMHAVPSKAGKVVITEESRQRRAKGKHMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVM7</accession>
    <name>M5FVM7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">DACRYDRAFT_54480</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627271.1">
        <property type="nucleotide sequence ID" value="XM_040775261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVM7"/>
    <dbReference type="STRING" id="1858805.M5FVM7"/>
    <dbReference type="GeneID" id="63690323"/>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OMA" id="LAYCSWC"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000020">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="19">
        <location>
            <begin position="33"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="185"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="454"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="554"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="636"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="683"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="1063"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EJU00374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1151" mass="129085" checksum="D5275D4BA9AB127C" modified="2013-05-29" version="1">MESSKWSAKNLSDPIKTVEDKWLLLPAFLKVKGLVKQHVDSFNYFVDVDLQQILRANNLVTSDVDPRFYIKYTHIAVGPPERADPDQGESPERFSVTPHECRLRDTTYSGRITVNVEYIRGNKKIIRRGIEIGRLPIMLRSNKCVLTGKSEAELARMQECPLDPGGYFVVKGTEKVILVQEQLSKNRIIVETDPSKGVVMASVTSSTHERKSKTYVLTKKNKIYLKHNSVTEDIPICIVLKAVGVQSDKEILQLVCGHNEEYRESFAANLEDAARLGVFTQRQALEYMGSRVKVNRPRPFGAPLAGTQGPRRPAWEEAMEALATIVLAHVEMEGLDFRPKAVYIAVMVRRVLMAMKDEKLVDDRDYVGNKRLELAGQLLALLFEDLFKKFNQDLKMNIDKVLKKPSRTEEYDVIKALTFHAQSEGITQGFIRAISTGNWSLKRFKMDRAGVTHVLSRLSFVSALGMMTRITSQFEKTRKVSGPRALQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDVEEEPIVRVAFMLGVEDINLATGPEIHHPDTFMVNVNGSIIGLTRQPGRFVVALRKLRRAGRISEFVSVYINHHHKTVHIAADGGRICRPMIIVEKGRPRVTEDHIKLLKKGHVTFDDFLRKGLVEYLDVNEENDSYIALYEREILPTTTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIGYNQFRRIDTLLYVMVYPQQPMVKTRTIELINYDKLPAGQNATVAVMSYSGYDIEDASMINRASLDRGYGRCQVYRKNVTLIRKYPNGTFDRLADAPIDEVTGRPPDKYSALQADGIAGVGEQLRPGDVYINKQSPANANDNSFNANVLDSTSTSLVQYKNTPMTYRSPVGGIVDKVMLTETENDQTLVKVLIRQTRRPELGDKFSSRHGQKGVCGLIINEEDMPFNDQGIKPDVIFNPHGMPSRMTVGKMIELLAGKAGVLKGKLQYGTAFGGSKVEDMSQILIEKGFNYAGKDYLTSGLTGEPMEAYVYFGPIYYQKLKHMVMDKMHSRARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGATQLLLERLMISSDAFEINACQECGLLGYNGWCPLCKSSKRVAKLTIPYAAKLLFQELMAMNVVPRLILDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW97</accession>
    <name>M5FW97_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_54265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627541.1">
        <property type="nucleotide sequence ID" value="XM_040775241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW97"/>
    <dbReference type="STRING" id="1858805.M5FW97"/>
    <dbReference type="GeneID" id="63690303"/>
    <dbReference type="HOGENOM" id="CLU_023208_4_3_1"/>
    <dbReference type="OMA" id="NAAMIGC"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072670">
        <property type="term" value="P:mitochondrial tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24134">
        <property type="entry name" value="ASKHA_NBD_OSGEPL1_QRI7_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="8">
        <location>
            <begin position="51"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="382" mass="41505" checksum="F9FE323993FF9A28" modified="2013-05-29" version="1">MIAYRQLSTVSRGRLSRLFSSPSCSKPFVVLALESSADDTCAAIVSSNRTIHSNIVLKQNHIHQIYAGIHPHLAILSHTEQMPFTVRRALDTAQMQMNDIDAIAFTQGPGMGGCLAVACNAAKTLAIALEKPLVGVNHMRAHALTVTLTNPEVPPFPHLTLLVSGGHTMLVLVHSEDKFELIAQTADEAIGCTFDRVAALLGLEWGKRGLGAALEHLASTSDTLDPSITLPTMMPGQLEFSFCGLRAATKRIIDHKQRSGELSDRTRADIAARFQQAAVMQLEDKLARAVKECRVRGVQPRAVVASGGVATNLYLRTRYTAEAAHAGTGEPLQVFYPPLELCTDNAVMIAWAAMGRLLKRERDGYGIRPLAGWKIDMDRPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWF2</accession>
    <name>M5FWF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_88689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629153.1">
        <property type="nucleotide sequence ID" value="XM_040776873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWF2"/>
    <dbReference type="GeneID" id="63691935"/>
    <dbReference type="HOGENOM" id="CLU_2277377_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11220" checksum="D49D2CB3872780E2" modified="2013-05-29" version="1">MSKPISQQYMTAVHPRTTPISDIYDDQLPLGIPHQLAFDLQYCYLNKGGYKGRTLSGCCYDLDIPTSIHANGTHIRGSPTHLSPVNLTKLTLSHAHLASMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN9</accession>
    <name>M5FWN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624744.1">
        <property type="nucleotide sequence ID" value="XM_040773856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN9"/>
    <dbReference type="GeneID" id="63688918"/>
    <dbReference type="HOGENOM" id="CLU_791217_0_0_1"/>
    <dbReference type="OrthoDB" id="3358646at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38624" checksum="A4B65A30F4D97E5F" modified="2013-05-29" version="1" fragment="single">MTSKPRRGAFKRGDSATSSPTAFGRLDLCGSNIIRLVGFPLDVLEGLQPVLRGDDGRGVLNVKKYTNEKGEKTAVLTLLGKPWTTDCGNVSTDILLTVICGHLHKHLFQPTTGLPPPRTTPPVHLSITFKRPVHPPSDAPRTRSVFAISFPTPTLVRTVSIPAVDEPLIFTEILGLWGGEVRDYRSLADGCYDIRLRPRRLFSSNSVGDNQTPLSALIEYLHSKGFPLIHSLHFHSKSPYPDFFLFDCPDGPVREDADPAYVNHVLTAQDGYYPDLVVEKKTKVKKERGPPTVEPKKGLFSFLRGRRSSNPNPTIAPAAVAAVTDFHSRHSLDSRPDASSFYANGVAESYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWQ5</accession>
    <name>M5FWQ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Asparagine-linked glycosylation protein 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALG14</name>
        <name evidence="13" type="ORF">DACRYDRAFT_23602</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Heterodimer with ALG13 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ALG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWQ5"/>
    <dbReference type="STRING" id="1858805.M5FWQ5"/>
    <dbReference type="HOGENOM" id="CLU_064541_0_1_1"/>
    <dbReference type="OMA" id="CRIVFIE"/>
    <dbReference type="OrthoDB" id="17098at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067254" description="UDP-N-acetylglucosamine transferase subunit ALG14" evidence="12">
        <location>
            <begin position="22"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="222" mass="24427" checksum="CFDA0045F47E5CC8" modified="2013-05-29" version="1">MVISLLSLLLLLVLIVIPVRAYAILLPNRPKPRTGPSKLAVFLGSGGHTSESLQLLRALPFTRYYPRLYITSSLDTLSIQKATSLESSLAPSLPPHAQQHTFLVLPRARRVHQPFWATPPTAIWSLVVAVWELSIRPALRGQACSDLLLLNGPGTCVPLLAAVYTSKFLALPAPRTIYVESFARVSSLSLSAKLVRPFVDRFVVQWPQAMGKGRGECRGWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX13</accession>
    <name>M5FX13_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="12">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_94354</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="12"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629425.1">
        <property type="nucleotide sequence ID" value="XM_040777216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX13"/>
    <dbReference type="STRING" id="1858805.M5FX13"/>
    <dbReference type="GeneID" id="63692278"/>
    <dbReference type="HOGENOM" id="CLU_003827_9_1_1"/>
    <dbReference type="OMA" id="YKANTID"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="4 11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 12" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="77"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU02531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="37052" checksum="BD9BB8903325030D" modified="2013-05-29" version="1">MFPLRPPLLRSLLTRRSLSTAPDPLPKDANWPLYLSIFGVSGLALWVYWQKTGQLQWDPVKNAQERRRGPTAALDRDEFRTFELKRKEPYNYNTSRYVFALPEKTATLLPVAACVLLKAADDETGPKDDKGRPVVRPYTPISDSRKVGEVDFLIKKYETGKFTPYLSSLEPGDKISIKGPLPKFAYEPNKFSQCGLIAGGSGITPMYQLLKHSLSIPEDKTHWTLIFANVSAKDILLKEEFDALAQAHPDRLNVVYVLDKPEKGFTGPTGYVTKELIKQHLPGPELGEKTKLFVCGPPGQVAAVAGKKAGMKQGELGGALKDLGYTEDQVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXU3</accession>
    <name>M5FXU3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PhoX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_78765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629755.1">
        <property type="nucleotide sequence ID" value="XM_040776358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXU3"/>
    <dbReference type="STRING" id="1858805.M5FXU3"/>
    <dbReference type="GeneID" id="63691420"/>
    <dbReference type="HOGENOM" id="CLU_002131_1_0_1"/>
    <dbReference type="OMA" id="AMYVVEV"/>
    <dbReference type="OrthoDB" id="120967at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="6">
        <location>
            <begin position="111"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="4">
        <location>
            <begin position="454"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="5">
        <location>
            <begin position="864"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1223" mass="135573" checksum="7A00F7F95EAA8653" modified="2013-05-29" version="1">MTPNTLPLPALALLPPVIGLLIPLLSPILRSPLALFLLSPFLFLTCLALALVAVILVAQTLDARSSVCERSQGALKQATRTLAFATPAAWSVVLTRASWPPTPLPALLPDQLALSVRLDNLLDLVLSSFVWPWYQQLSRSAAFPAAIKCALHHAIGLILDRGQEVDPLSVATQRVLPKLTAHINRFRAAETLLRGADLSRHLTQSSSLDLMLAQKYGTLHPAVGNISSVDTRQTEEAHLRNMIGRVMPKLLPESEAASPAVSIIVREIVACVVLLPLVDMLSEPDFWNRIAEDVTSEVIQQQHLVSRVRHILSLSTSPPGASVSLSSPTAQALQPIRLRMEDISPRTSGKQFESFLRTVARCDSLLDARRLKNDISSEIRKTRVLLASSQTKEDVLGGYKPELIVKYLDRLYTASRAVEKRIGVLSGEPTLPTIPTSSLAPASPPLRLNGPMPTLRTILTTPESLSYFMEFLDRRGKSLSVQFWLTVESFKDPLENVESDGNEETDEPDDNVTLPNGGTGTLREDVQLIWDLYFSEASAQRPKVSQKNIDAVRTFLNKEGPVTRGDERKARQAVLRAQREMEQEMEGAFEEFKRGELWLKAVAAGGNVSTSTSPGLPRVPSQPDLQSRTEESKRKRPLPQYITHSQPVVLTTKTVVRGRVEPEAPARPPSVRAGSADSKSSAPQRHASRASIDSTKTNLDALFGAAPKDRAPLFGDETEERARGVDIEAIQAALTDIIADESDHRQSDERYVDERISGLAGLDLEPNSAVREKEDEEWKLAIPGDPHLLSSIARLAEKVANLEQQSTLLDALTRKAELTGDNNELRLLSTSKAALERELREVRFQREQFVMQERNGILTPERTRVKIVGTTMTDEEGGVGRQVVKYAIQVQQLEQDGADEGEGSSSGWVTARRYSEFWALQQRLKEKFPEVRHLELPAKKLVNTISAVVDARRIALEKYLQTLLTFPTVCASEDLRAFLSRSPKYTPTSSIISQYASLTGSFLSPSTDLMRSLTRLTTSIADDIIFGPSMLDVLIQRLTQQAKTEEELVKLTEAEGLRPLEGETGGATFAAPICDLILSVFELNDRNNWLRRQAVVIILQQVLGSTIERKLRDTLKASLEEHNIVAYFDKLHRVVFPGGKFRTSGPPRTAEEKARTRDEANRKLSALMPDLFSNMIGRSNARRGARRMFAVLQNQRLNRHIIYTVMDEVSRTEPFIGLKLTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXU4</accession>
    <name>M5FXU4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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            <end position="67"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="108" mass="13123" checksum="563E70318ED5FBFE" modified="2013-05-29" version="1">MSLPAEEPRLGQEEPELEPELELLQQEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDWEMIPDNLSAEDEKIFTAFYVKMNGHFTNAQYNTLNFTYPDVFYDLPYIE</sequence>
</entry>
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    <accession>M5FYB2</accession>
    <name>M5FYB2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arl8a protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22631</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lundell T."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
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                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
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    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
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        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="52"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="182" mass="20558" checksum="9DDFF477A1C37FCB" modified="2013-05-29" version="1">MSLFFSAIYNFFRNIFFAKQVEISVVGLQASGKTSFVNVLGSGQWSEEVVPTVAFSFRKVTKGNITLKIWDVAGQPKFRNMWDRYCRGTNAIVFVVDAADKDKIDTARFELHNLLDRPHLAGVPLLVLGNKNDLEGHLPVNELIPLLQLDRIQNRPVSCYSCSMKSQHNLDVIMQWLAARAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
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    <name>M5FYB8_DACPD</name>
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        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_41010</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="63689557"/>
    <dbReference type="HOGENOM" id="CLU_018688_2_1_1"/>
    <dbReference type="OMA" id="ITINILW"/>
    <dbReference type="OrthoDB" id="3221808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="122" mass="13634" checksum="FB2581AB44810279" modified="2013-05-29" version="1" fragment="single">WKLYVRKAEEHDSTLLKKWNEGLDVFLLFTGLFSAVLSTFLIASWSSLQQNTTQASLDALGSLSQQLDALKRGQAADPAPSYLPEPFEVPAWAVAVNALWYTSLFITLFAAVLAMLVKDWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ06</accession>
    <name>M5FZ06_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_60154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623605.1">
        <property type="nucleotide sequence ID" value="XM_040775617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ06"/>
    <dbReference type="STRING" id="1858805.M5FZ06"/>
    <dbReference type="GeneID" id="63690679"/>
    <dbReference type="HOGENOM" id="CLU_1880334_0_0_1"/>
    <dbReference type="OMA" id="VWSSFRI"/>
    <dbReference type="OrthoDB" id="2998253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="15637" checksum="D5805BE8E1816531" modified="2013-05-29" version="1" fragment="single">MGEFGQEPEKRPQFGDRWNASAPQDEILSLGRVEEMKEKLEAARTVVLALELALQTEKNILFRLRARRAPITRLPDDVLSLIFAHGADILQPLVSSDEEKAPRTRRPPFQLVCAQVCDRWRRVAFHTAEVWSSFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ11</accession>
    <name>M5FZ11_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625714.1">
        <property type="nucleotide sequence ID" value="XM_040773655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ11"/>
    <dbReference type="GeneID" id="63688717"/>
    <dbReference type="HOGENOM" id="CLU_118666_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067456" description="RING-type domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21593" checksum="37C72947B6D7E62C" modified="2013-05-29" version="1">MQILKFLLAVLSFSVLATSLPVHTSGSGSLALRNADLEERSTASGLDGSKDVLARSFDDVDSDLEAREDEDLCSMCMDPKAEYSNCPNGQHHPAHAKCLAHLIQHQFNEGQELTCPTCRTSTTTLLQNVKNEPNQATSSAKKEPAPKEATLSAKKIMLKPAPRKAVSNRPGPSKSARGRARKRAARKTAQAKRKDVESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ67</accession>
    <name>M5FZ67_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628701.1">
        <property type="nucleotide sequence ID" value="XM_040768495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ67"/>
    <dbReference type="GeneID" id="63683557"/>
    <dbReference type="HOGENOM" id="CLU_1981539_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="13976" checksum="50E9CA6A15F1AA7C" modified="2013-05-29" version="1">MTSSRQRRTTAPLWVEEPRILLPCLALPTSAPLPVHSDTVRAQQHRSPPLNTILWFSRGSETDDVSRPVTIWPLALLSPGAVIGWDTSSQLPRTPGLSWTSFAAVDLLVRIYTLVDGPFLPSPLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZE5</accession>
    <name>M5FZE5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_22326</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628786.1">
        <property type="nucleotide sequence ID" value="XM_040772745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZE5"/>
    <dbReference type="STRING" id="1858805.M5FZE5"/>
    <dbReference type="GeneID" id="63687807"/>
    <dbReference type="HOGENOM" id="CLU_042529_21_3_1"/>
    <dbReference type="OMA" id="FWYPKDF"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF128">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU01889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="232" mass="25616" checksum="01207D77F9C3867B" modified="2013-05-29" version="1">MSKAFVQKPAPHFSGTVVEDGLFKDISLNDFIGKWLVFFFYPLDFTFVCPTEILAFNRALPQFEGIDCAVIAASTDSIYSHLAWANTPRAEGGLGPNLRLPLLADKNMQIARDYGVLIEEEGVALRGLFIIDPKGILRQVTINDTAVGRSVEETLRLVKAFQYTDKHGEVCPADWKEGEDTLVADVKESRTYFAKQGDMENVTTGVNGDVAVKKRPASKTEENGPNKKAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZF0</accession>
    <name>M5FZF0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625844.1">
        <property type="nucleotide sequence ID" value="XM_040773523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZF0"/>
    <dbReference type="STRING" id="1858805.M5FZF0"/>
    <dbReference type="GeneID" id="63688585"/>
    <dbReference type="HOGENOM" id="CLU_1415123_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="192" mass="21619" checksum="C487FBFA99908ADF" modified="2013-05-29" version="1">MLRVALCHSYLPRDNISHISAKHHPLSVGTPPTQPTCIPILGMLTLPPNWCHDLKRRADKYPDILTIRMTSIALSVVNSRRAAFEIMEKRAWINKPLTKNGDGARADFSIRIGQAQDSSQTAVPKLHKECRWMLSVALSPRVVQAYGDEQAHQFHRVALDMLSGSGKYRSAIVRSVLDRARAYMKLRARLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZI1</accession>
    <name>M5FZI1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_107842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628182.1">
        <property type="nucleotide sequence ID" value="XM_040768547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZI1"/>
    <dbReference type="STRING" id="1858805.M5FZI1"/>
    <dbReference type="GeneID" id="63683609"/>
    <dbReference type="HOGENOM" id="CLU_1340337_0_0_1"/>
    <dbReference type="OMA" id="GIENDHA"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="205" mass="21418" checksum="1F4F5CA2173410C4" modified="2013-05-29" version="1" fragment="single">MSSPDLIAPRLSRTPTLVDQNEERSLDALTLSTPPKKAEAVVTESSESEENVTFKKDFGFWMIILSLCVTSILAALDLTAVSTALPTIVDDLHGGSDFVWIGSAFTLSSTAILPLSGNIATIFGRQWALLSFIFLFAVGSAVTGSARDMPSIIAGRTVQGLGGGGILSLAEIVVADLVPLRERGVYLGILGATWSLASAIGPPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZS9</accession>
    <name>M5FZS9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase-assembly factor COX23 mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630420.1">
        <property type="nucleotide sequence ID" value="XM_040772224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZS9"/>
    <dbReference type="STRING" id="1858805.M5FZS9"/>
    <dbReference type="GeneID" id="63687286"/>
    <dbReference type="HOGENOM" id="CLU_157422_2_0_1"/>
    <dbReference type="OMA" id="GGDRDMC"/>
    <dbReference type="OrthoDB" id="9971592at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051040">
        <property type="entry name" value="COX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="10512" checksum="2A4E59721EDD09CB" modified="2013-05-29" version="1">MATKYIPPEPTNSGPEPAPTGQQPTNYKQVFEGRVVTKFVDPCEQAAKESMACLNRHSYDRDQCLDFFQAYRDCKQEWLKQRRVDRANRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX7</accession>
    <name>M5FZX7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_119561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623965.1">
        <property type="nucleotide sequence ID" value="XM_040770822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX7"/>
    <dbReference type="STRING" id="1858805.M5FZX7"/>
    <dbReference type="GeneID" id="63685884"/>
    <dbReference type="HOGENOM" id="CLU_655553_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="191"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="419" mass="45286" checksum="64CE8172CB06A5B2" modified="2013-05-29" version="1">MAQQLHPQQQQQPAQIQPEGGNTEQNVEPAMEESTDVPSTITPIPQPTPASPLVTAPAPEPNMPGALPTAPAAEQPPPQPTQEGTAHIHAWQIPGGMVFTLFVGPSVPIPGMATAPPTFNPFPIPGAAPGAEAGLGGGAGEWFIPFFPPWFFPQEKEPDYARGALLMRALEQVEPELLSRFQRVQGEDQRCPVCFERLGDAPAVDPPAQDSQAPAQAQARQNHIPPCPFPQAEILALPCHHPFHAGCLFPWLGEHTTCPTCRFDLDPESQTLTPPPQGGRYSPYLSQEARKAGKWNLPLGPSGQILRESVVMREHEQGWTCADPGCLHALPNPSYAQHPAGEPKALQIHLLTQLDPDAEPACEHAWHPECLVGSVRSRAGGVEVAPGGTRVECALCRDGREGWVMRDVWEDGVRAWEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5G001</accession>
    <name>M5G001_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_25226</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623995.1">
        <property type="nucleotide sequence ID" value="XM_040774069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G001"/>
    <dbReference type="STRING" id="1858805.M5G001"/>
    <dbReference type="GeneID" id="63689131"/>
    <dbReference type="HOGENOM" id="CLU_000288_26_2_1"/>
    <dbReference type="OMA" id="NFTHRVH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13279">
        <property type="entry name" value="PH_Cla4_Ste20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000139">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000705">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="93"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="535"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="259"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="352"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="482"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="809" mass="87726" checksum="AFD7453ED8A94384" modified="2013-05-29" version="1">MAFESPRNLTPTALTPSRPAPPAPLQRRPTDLSLPISNPLPLQLSQPGSATSSLRSYSPAGASLNGSSPGPGGSMWTSGGREDPYGGGIGSMAVVQSGWVQLKEEGFAGLFWQRRYMVLREGSLSFHKTESSGASSTLSLRDIQSVSRVELRPYCLLIELSASRGKLHISFKSDAELYQWQEEIYSRSPSAGVSHPTDFVHKVHVGFDPVSGAFTGLPEQWTRLLSASQITKEDYAKNPQAVLDVLEFYTDRQKREAEGGDLTIAGPGNAAVVTRPPPPGRFAGGTGLGGQLAQQKNADANGSTTSLNTLATTTTANTVVSDSSRAPLIKQNTAPAALDTRNAESRLRELTLANSARPLPQASRPAPAPPGSRPPVQANRPAPPPPGQRAQPKQQDYFKDNFSSPVTTGVSSSQMEERGPHIPATLAPMSDTTRQQVSPAKSAPTSNANSSTAAGALAGPPPVKPLQTAKKLPVPATDPLATAMDKLEAKSPEGIRERELKKKAEEEKRISTLSEGQIMERMRAVVDRENPKELYARIRKIGQGASGQVWVAKSNMGGHKVAIKQMDLSHQPRKELIVNEIIVMKESQHPNIVNFIASYLVNSNELWVVMEYMEGGALTDVIEHNNLSEDQISAICLETCKGLCHLHDQSIIHRDIKSDNVLLDAQGRVKITDFGFCAKLTETKSKRATMVGTPYWMAPEVVKQKEYGAKVDIWSLGIMAIEMIEKEPPYLDEEPLKALYLIATNGTPTLKNPEALSRELKSFLSVCLCVDVKSRATADELLRHEFFQLACSPQQGLAPLLRWRNNQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G038</accession>
    <name>M5G038_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630520.1">
        <property type="nucleotide sequence ID" value="XM_040772260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G038"/>
    <dbReference type="STRING" id="1858805.M5G038"/>
    <dbReference type="GeneID" id="63687322"/>
    <dbReference type="HOGENOM" id="CLU_076940_0_0_1"/>
    <dbReference type="OMA" id="WPYVGFV"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF11">
        <property type="entry name" value="MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="71"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="276" mass="30579" checksum="7E5863D194EAB2F9" modified="2013-05-29" version="1">MISPRCLSQRLPFNTARSLATSRLPGMPTPDGAGFPIDEPLSLTFLAIIRHTLRRQSLMKHEPPFSSSPVAQNAAVLVPLCNVNGNPGILFEVRGKLRSHAGEVSFPGGRTDEEDDTFLATAIRETDEEIGVGPGQIEVLGTFGPAELSLWKLRVHPFVGFIYPTLERPELRPNEALPSIALSSLRPNPPEVSHIFHLTFREMFDPHRLRVHDFRGYTPYWAIDVSDKVEGLGLHWKTLAGQDELGGSGRPGGKGLEIWGLTGWYLNVFLKRLGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0M6</accession>
    <name>M5G0M6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF775-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_52826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628572.1">
        <property type="nucleotide sequence ID" value="XM_040775130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0M6"/>
    <dbReference type="STRING" id="1858805.M5G0M6"/>
    <dbReference type="GeneID" id="63690192"/>
    <dbReference type="HOGENOM" id="CLU_084839_1_1_1"/>
    <dbReference type="OMA" id="QVDETHC"/>
    <dbReference type="OrthoDB" id="10248398at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="4">
        <location>
            <begin position="161"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="218" mass="23788" checksum="ACB7E0277AAB5072" modified="2013-05-29" version="1">MFGCCVAGRLVQTDLVQMDSTHSVFNIPSASTVNHVCVFLTGQTPFPDGWGATVHWNWPGRGFQLLGMLSNQKPSAIFRLRGILPGQSSATDTDMGMDDETGVSATSNSSAGDMAQIGLSIEPLDQVQQQVASLSNVSTSKSLVPVRPQMPPQAQTASDPVYLTELILKNLSNYLTSFTHDNTLNPTNTVQIGIIQKWYENLMNKLRLRGTAFLERQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0W4</accession>
    <name>M5G0W4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_28664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0W4"/>
    <dbReference type="STRING" id="1858805.M5G0W4"/>
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    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="APH_ChoK_like"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
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        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="186" mass="21162" checksum="3981901FA859D268" modified="2013-05-29" version="1" fragment="single">EAHAMWLVKRHTNVPAPMLVDYITCAIESHGFSYNAAYTLMTEVPGRPLSEVAHSLSDDELETIGLQLRGYVEELRAIPNPYPKQVCSASGGSIDCPRFTDAWEIPAYVDVPAFYAWLRMMVDKYWEICMKARLEPIFAKFDGPTVFTHGDIADRNIMIQDGKISGLIDWETAAWMPVYWEYYASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1E2</accession>
    <name>M5G1E2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_778496_0_0_1"/>
    <dbReference type="OrthoDB" id="3410854at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="356" mass="40612" checksum="5384AFB19939C9C9" modified="2013-05-29" version="1">MAEHQRLQAGNQTQLLLWPLLMSSSSGPLGISFLPDTCQWGARAELTAGPKPILGTTLDGLDYWHWTMHPWMTQDVHQCKTCYFYEFLPKLEDLPQRPGLFLHMASINGGDKDLEPEPWFWVSRNLRKSPAYMEIIECFVYVFSTVLMNSKVHKYNKYVKSKDDIQAGLAQVSEHDLGVDMNLEPDIERSMREALDECLSLGAPLIVKQEPREHNAELKTVLALTDPGKGKGCETRDSNINMLQGKVDTNNVRQYPYHPDPVHLAAELHKLSHQGLHKYKCPPPNMVLADLPGTIQIYLQEYNKTILEQVAHHAEHKLKLIWAYDSPVHWDDLVTDLVGGDWSDSLLQLMYKICCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1F3</accession>
    <name>M5G1F3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1F3"/>
    <dbReference type="GeneID" id="63685260"/>
    <dbReference type="HOGENOM" id="CLU_162866_0_0_1"/>
    <dbReference type="OMA" id="HYQGGHI"/>
    <dbReference type="OrthoDB" id="3359661at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="120" mass="12420" checksum="2CDA2B6A284F68E9" modified="2013-05-29" version="1">MGSLCSRPHMPGEGQTLGSGPAPPQRTQPAGPGSRPAPQQQSSPGRTLGSTTHQPAGTPGMSVPSREAAAQAAEARAKAANTRGVNVSNPKAGKLSANLDRQKKDGRMAEEQQPERIIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1S8</accession>
    <name>M5G1S8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Swi5-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_105225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWI5/SAE3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631050.1">
        <property type="nucleotide sequence ID" value="XM_040768058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1S8"/>
    <dbReference type="GeneID" id="63683120"/>
    <dbReference type="HOGENOM" id="CLU_106110_1_1_1"/>
    <dbReference type="OMA" id="RQVHNDY"/>
    <dbReference type="OrthoDB" id="255837at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032798">
        <property type="term" value="C:Swi5-Sfr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034974">
        <property type="term" value="C:Swi5-Swi2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010772">
        <property type="term" value="P:meiotic DNA recombinase assembly involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000709">
        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010760">
        <property type="entry name" value="DNA-repair_Swi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07061">
        <property type="entry name" value="Swi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9131" checksum="369461BFE851C8A4" modified="2013-05-29" version="1">MPSSSKELTKEEEEGIREEIAELENELGGKDPDAAIKEHIALLHQYNELKDATQIMIGKMATMKDTTVRKLHEDYGLTSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G257</accession>
    <name>M5G257_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_79069</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629197.1">
        <property type="nucleotide sequence ID" value="XM_040776372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G257"/>
    <dbReference type="STRING" id="1858805.M5G257"/>
    <dbReference type="GeneID" id="63691434"/>
    <dbReference type="HOGENOM" id="CLU_016733_0_1_1"/>
    <dbReference type="OMA" id="NMPQTAV"/>
    <dbReference type="OrthoDB" id="5391403at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="57"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="136"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU02300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="405" mass="44039" checksum="A37FF358840AB08A" modified="2013-05-29" version="1">MPKTPMALFAAGMRRAPPRSIRRFSLALQSSARRSSRVTRSAVTFQLAGFRTSALAQEIVKVPQMAESLTEGTLKSWTKKVGDRVEQDEEVAVIETDKIDVTVNAPKAGRIKHLLAAEEDTVEVGQDLFELEPVEGGAEAPAPAEVPEKAAAPGPEEPKPAAKEVEKAEAAPAHVPVPEAVAPKEEKPKEERPAKPAAYRGETRIKMSRMRLRISERLKQSQNAAASLTTFNEIDMSSLMDMRGKYKDLVLKEHGVKLGFMSAFAKACCLALKDFPVANASIERDEIVYHDYVDLSIAVATPKGLVTPVVRGADELGMIQIEKEIGELGKRARDGKLGLEDMAGGTFTISNGGVFGSMYGTPIINLPQSAVLGMHAIKDRPVAIQGKVEIRPIMIVALTYDHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2I0</accession>
    <name>M5G2I0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624870.1">
        <property type="nucleotide sequence ID" value="XM_040773895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2I0"/>
    <dbReference type="GeneID" id="63688957"/>
    <dbReference type="HOGENOM" id="CLU_2885720_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067458" evidence="1">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="63" mass="7238" checksum="5D19578588EAF475" modified="2013-05-29" version="1">MTILLLLPLLLVFLLVLTPRVTPTRAQIPQLPDLNSRSVMLDATRHRLETLFLTEPVPHSRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2N9</accession>
    <name>M5G2N9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_65091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629853.1">
        <property type="nucleotide sequence ID" value="XM_040775772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2N9"/>
    <dbReference type="STRING" id="1858805.M5G2N9"/>
    <dbReference type="GeneID" id="63690834"/>
    <dbReference type="HOGENOM" id="CLU_001265_46_14_1"/>
    <dbReference type="OMA" id="QIGFAGK"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU02959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="551" mass="59966" checksum="E18475FD04FE5245" modified="2013-05-29" version="1">MSVYEKREQHARPNHGDVRGGLEDFERDDPSKPPFILNWTEVKILGIAGVGFFLDAYDLFIINQVTSMLQWRFYGGKSLPSTLSGLVKAAANIGSVIGQVSFGLMGDYFGRKAVYGKELIIIIVATIFCISAPSSVGGDGVLIWLTVWRIVLGVGVGADYPMSASVTGDRAILRKRGVMLCYIFANQGWGSFIGSIVTMIVLACYKGVLDNDNPANWTKTDGIWRIIVGLALIPAFGTLYQRLTLPESVRYNRAVAGEAPPVDASMKYADVENGSANSGPGFKQTYDAEGNPVPRPNPDVVATEELDPSVLPKEVIVAAQRQHWKEFRAYFGQWRHFKILIGTTCCWFLLDIAFYGINLNTNIILTAMGLGGSTGTAWNRLFQVATGNLIVTALGFVPGYYVSVLTIEYIGRKPIQLMGFGMTALMLALLAGLFPRLDHGGFIALFTFLQFFFNFGANTTTFLYPVEVFPTKYRATAHGISAACGKCGAIAASFGFNSLVGPIGTANVLWIFFGVSILGIPFTFLLPETKGRDPDVILAEEEKRGLAPISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G363</accession>
    <name>M5G363_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Laminarinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_88158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630033.1">
        <property type="nucleotide sequence ID" value="XM_040776839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G363"/>
    <dbReference type="STRING" id="1858805.M5G363"/>
    <dbReference type="GeneID" id="63691901"/>
    <dbReference type="HOGENOM" id="CLU_016972_1_1_1"/>
    <dbReference type="OMA" id="CSYQPGC"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="11"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="304" mass="33361" checksum="8FE7396DF42B17E0" modified="2013-05-29" version="1">MLAALIALHALTYKLKDQYVGPSFLDGFDHWPYSDPTHGRVNYVDQATAIVNNLTFAEGKTFVMRADDTTVLDPNGPGRNSVRIQSKNMYSVAVMVMDIRHMPNGCATWPAWWTCGNNWPYGGEIDIIEYVNGQSPNHMTLHTSPGCTQPQSRTMTGTTTSTDCDANVNYNEGCGVQSGNSASAGSGFNSIGGGWYAMERTTSSISIWFWPRNSRTVPTVVKGGARAVNTKLFGTPDATFVNNQCDFNSHFQPHNIIFDLTLCGDWAGNNYPASCPSNCVDYVNNNPAAFSDAYWDIAALRIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G394</accession>
    <name>M5G394_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Erg28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20335</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631575.1">
        <property type="nucleotide sequence ID" value="XM_040771895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G394"/>
    <dbReference type="STRING" id="1858805.M5G394"/>
    <dbReference type="GeneID" id="63686957"/>
    <dbReference type="HOGENOM" id="CLU_114589_0_0_1"/>
    <dbReference type="OMA" id="AYAAFHI"/>
    <dbReference type="OrthoDB" id="6485510at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="142" mass="15261" checksum="33B24F777784262A" modified="2013-05-29" version="1">MEHVQEFVTKYLPIPSLLPAWTLLVGTTAIINGLQNFLGDSGSKLVYIKGAKKGLVNPLQARNFGLWTLTAGVVRLYAAYNITNAAVYDIAIATYVIAAVHFFTELLVFGTCGLTGGAISPIVVASSSLFWMISQRAFYLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3L6</accession>
    <name>M5G3L6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625250.1">
        <property type="nucleotide sequence ID" value="XM_040770633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3L6"/>
    <dbReference type="STRING" id="1858805.M5G3L6"/>
    <dbReference type="GeneID" id="63685695"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_3_1"/>
    <dbReference type="OMA" id="SITPMIL"/>
    <dbReference type="OrthoDB" id="3346544at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="37831" checksum="47C100D5F7544CEE" modified="2013-05-29" version="1">MAPSTVVGTAYMTFFGGLSAWGLYGLYFGLFNVSMYILCFRSTHRRRNIFLITATIAIFLFSTIDIIIESNSLLIGFFDTTTALQRDQHFAGGGDWTYAFQDAAQLTNMLVADVVLLYRVWAVWGRRRSIIAFNTLLWLATLGKSSSRTSRSFADYLLACSIRVIQLEAYVVESVTHAAALYVLNNWAIATQALTFSQNVIATCLIALRLWALDHRATTMQRGKLMPIVLIVVESGAIYTSLLLANIVVSSLLNWAVLFVTQLISPIIGITFSLITVRVGLGLASEGTPAASAGESMSSGFVDVTFGDPTDNTERGRPRDDAASADEEGISPETRQNSEKSWKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4R6</accession>
    <name>M5G4R6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cofilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Actin-depolymerizing factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630104.1">
        <property type="nucleotide sequence ID" value="XM_040772412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4R6"/>
    <dbReference type="STRING" id="1858805.M5G4R6"/>
    <dbReference type="GeneID" id="63687474"/>
    <dbReference type="HOGENOM" id="CLU_094004_3_2_1"/>
    <dbReference type="OMA" id="FKTECRY"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="3"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16020" checksum="28A6B0AE2D6542A9" modified="2013-05-29" version="1">MSSGIVPSADVLRVFEEDLKRNKKFKYIILGIAKVVDPSNAKPVDTIVVTKTSEEPSWDKFLAELTDTECKYAIYDFAYEVDGGGQRTKIILITWAPDGAQTKERMIFASSKAALKATLSSGIAAEVQANDLSEITFEIVRAKLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G521</accession>
    <name>M5G521_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_19889</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632255.1">
        <property type="nucleotide sequence ID" value="XM_040771704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G521"/>
    <dbReference type="STRING" id="1858805.M5G521"/>
    <dbReference type="GeneID" id="63686766"/>
    <dbReference type="HOGENOM" id="CLU_017290_0_1_1"/>
    <dbReference type="OMA" id="NIMTFRL"/>
    <dbReference type="OrthoDB" id="77835at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006576">
        <property type="term" value="P:biogenic amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000005">
        <property type="entry name" value="Probable glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF12">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GS catalytic" evidence="8">
        <location>
            <begin position="127"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="53268" checksum="42FE8FFFA87ECAAB" modified="2013-05-29" version="1">MPTPVETPGAPRTLKELEQLLSNDIKVKVAGVDVDGILRGKYMSKQKLISAVEGDGFGFCSVIFGWDMHDSVYSKELLISNKATGYRDLLAKIDLTTYRRIPWEGDVPFFFVSFLDPDTREPVFADPRSVIKKAMDQASAKGWQCMAGAEYEYFNFKETPQSLVDKKYSELSPMTTGMHGYSLLRTTLNQDYFTKLFDESVKFGIDIEGHHTETGPGVFETALAYTSALRMADNAILFKLLAKSVGMQLGVLPTFMAKPWAGLPGCSGHIHVSLRDVDGKNIFSWQSKEPRRDAANPDVQFLSKEGECFLAGVLDGLPDVIPMLVPTINGYKRLIGGENFWAPNAVTYGYDSRAASIRVLAPPGVPATATRFEIRVPGADMNPYFAFSAIFLLGLRGIEKKMVLHCPPLSDPSVTRENVTKLPMSLEAGAERMMRRGSVAREILGDKFVDHFGGTRMHEVALWNEAVTNWEVERYFELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5C3</accession>
    <name>M5G5C3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linoleate diol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LDO3a</name>
        <name evidence="6" type="ORF">DACRYDRAFT_67793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627924.1">
        <property type="nucleotide sequence ID" value="XM_040775859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5C3"/>
    <dbReference type="STRING" id="1858805.M5G5C3"/>
    <dbReference type="GeneID" id="63690921"/>
    <dbReference type="HOGENOM" id="CLU_002329_0_0_1"/>
    <dbReference type="OMA" id="PYANFKE"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1034" mass="113633" checksum="7E40F068F4667F9F" modified="2013-05-29" version="1">MSGILNAISRASNLISASLAPVDTDGGSLKAPPGILARGISEIEGLVRSGSAVGPSDLPALLDAIQNLNGPGIDDRLFLLEKLLVLMSRMPADSAINQKMQAFFIDTLYKDLPHPPSAYLAPAPLISPDPHPKRAYNYRSTNGDNYSQAIPLLGRAGMPYSRTVPSASCVPPSSLPDPGLVFDLLLSRPAGKFKPHPGGLSSLFFGMANLVIHSIFDTNRTDWNINDTSSYIDLSPLYGNGVSKMKAPPEALRRFDGTGRLHEDVFGDARLLFMPPTTAVLLVLLCRNHNYIAEKILSINENGTYLNPPPHDETARRAQDDEIFERTRLVNSGFFARVVLYDYVGGILGMTRDGSAFRLNLDQQIRRSDHEIAPLGEGNQISAEFNLLYRWHASTSAPDKEWIDDTFKTILQGKPYNQVTVEDFTTAAGKFMRPNDPDPKKWEFGGLKRDPVTLRFDDAALAKILKDATEAPAHAFGARQTPEALRVVEIMTILQGRSWAVCTLNEFRSFFGLKPYANFKEWNPNPEIYNAAQALYGHIDRLELHVGLQAEEAKGAMPGAGLCPSYTVSRAILADAVVLCRADPYLSSEFTPYNCTAWGYQDCAMNPNDGSFGGALTKLMLRHLPGQYKTADAYVHFPFLVPNEVRRTMELRKDPMVHKYDWKRPVAQTTVPAGTGIKTLNLITLPAQNDRITKLIGKGKINRALVNQQLLAYLSQPKTDDIFAEITKKLIDENSVLRPGFSSKQVDIVQTVINMVPVYFVANYILGLPLKTTANPHGVYRPEELYAMFANAADYILYDQDAPDQWCMCDNATGCADMMRKEISANLDRLAYGVWSITGLVDTVADMWASKTNQSDTFLSTLLSAGKKTGMTVPDISASLFAVVIPSVPQFSAVVTQLLDFWLSKDQTSKKTDLAQMAAAGPGMNPQIAAYAKQAIKSIPALTPTDASAINGSMAVANPLNSIEGLMSEKIFDKTAPVVLRSIFSLRNVRRAPGQSGFLPMFTQTVLDQPQTFFINNESGLSPWPTRLMIQYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5H4</accession>
    <name>M5G5H4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_49850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630838.1">
        <property type="nucleotide sequence ID" value="XM_040774946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5H4"/>
    <dbReference type="STRING" id="1858805.M5G5H4"/>
    <dbReference type="GeneID" id="63690008"/>
    <dbReference type="HOGENOM" id="CLU_029204_1_0_1"/>
    <dbReference type="OMA" id="CVGVEVW"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="83"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29438" checksum="CF58CFCAFE066785" modified="2013-05-29" version="1">MSTSPKPYAPSIASSLSSTWAHSSPFAAHHHPTAPPTGAPGFWEPEFDWDKGDWRSDPSITDSKRRLLTEKVDLRGRGLQTSPVLLAEVAALIRPWLPPLARLPKSWTLLYSLDQHGISIHTFYREIAKSFEPPNPSIGGCVLAVRDERGGVFGVWIGEKIRMGGGSYYGSGESFLWKLVVLPKGEEAGSIKVFKWSGKNDYVALCEDDYISFGGGDGRTGLYLDSAFDRGYSERCPCFENEPLCYTTDGVKGRFSCVGLEVWRVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6A1</accession>
    <name>M5G6A1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632680.1">
        <property type="nucleotide sequence ID" value="XM_040767899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6A1"/>
    <dbReference type="GeneID" id="63682961"/>
    <dbReference type="HOGENOM" id="CLU_987020_0_0_1"/>
    <dbReference type="OrthoDB" id="10622321at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="282" mass="28693" checksum="ACDB9859F6D3B33E" modified="2013-05-29" version="1">MSILLPSPSYSPSQYAYPYPSPLPHMAAPAPPPRRPSTRTRLRLPTPLPAPPVPPTLVNSPLLREGSKFRQRHTLEERRGTREGAERDAWGIGDQVPLRASTAYAYGASTSTSSGTYASWDGERPRANGVNGNGNGDGSGLPSGTGRQELQRAKTDSFLPSTTGQARAHPTPTPTPTGGWGRTGSSAVVPLRTGVTQGAGAGAGGGAGAGAGVGRGIGAGTSAQPPPTPAPDHARTGSTVYAHSRLGGDSPAAAGAEAEMTCPHPTARPASTKQVKYLAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6G7</accession>
    <name>M5G6G7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_98416</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632745.1">
        <property type="nucleotide sequence ID" value="XM_040777528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6G7"/>
    <dbReference type="STRING" id="1858805.M5G6G7"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:glutamate 5-kinase activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acetylglutamate kinase-like"/>
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        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
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        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="52595" checksum="67A554E252B4BB54" modified="2013-05-29" version="1">MTSRAKSNRHLTIVIKLGTSSIVSESTHQPLLAILSSIVETVVNLRKDGHRVVLVSSGAIGVGMRRMGVKERGKTLAGVQALAAIGQGRLIALWDQLFAHLDQPIAQVLLTRGEVSDRTRYLNACNTLAELLSMGVVPIVNENDTVSVSEIKFGDNDSLSAITAAMIHADYLFLMTDVDCLYTANPRKDSEAKPVFVVADVAQIRQSVSVSSLGSALGTGGMETKLIAAELASGAGVTTVITNSKSPSNIGAIINYNLKHAPDSPALTAASTSSSSSNLTSNSTSTTTTTILVPATQDPRPPHTIFLPKPSPLADRKWWILHGLHSAGTLLIDSGAHRALSRRESGGRLLPAGVVGVRGTFASQQAVRVVVRRRRGEGGGERRDLPTPGEYTPDLTFTPTAASALPSAIALQHRIAELAPSNPANPGSPLPAGPAGEKDKEEKEEEWEEVEVGKGLSNYNSWEIDKVKGLKSSQIESILGYADSEHVAGNITLRVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6K0</accession>
    <name>M5G6K0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626290.1">
        <property type="nucleotide sequence ID" value="XM_040773470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6K0"/>
    <dbReference type="GeneID" id="63688532"/>
    <dbReference type="HOGENOM" id="CLU_888581_0_0_1"/>
    <dbReference type="OrthoDB" id="3199068at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="36"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="35880" checksum="11BE6C3E2FE3FFFB" modified="2013-05-29" version="1">MKLDHAENGGGSVGGEGQKPAEEGVHRHPKWYFSDGSIVLRIENTLYNLHQSFLSCSSVFRGMFALPPSAEQEGGSDENPVVLSEDRAEFDVLLEFLYPSLDFSISSYAMDTLCMLLRLADKYDFADIRMHVVHQLLAPVNPHNLSWQRSLDLGTRHGTPQLVVAGSVGICLQSTPLDVEDLRVIAYAFPEDDRVAALLHARDKARDHLYTKAFADHHSQVCTSECRSLQRISQHLRVVLRDPAVCGGEKTFPGAVKKLFLRRDTQGMMGPSLWNCSKCVEQADALVERVLNTAAMRELVQEVMPWCRSIKPLPRGQGVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6M0</accession>
    <name>M5G6M0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626310.1">
        <property type="nucleotide sequence ID" value="XM_040773478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6M0"/>
    <dbReference type="GeneID" id="63688540"/>
    <dbReference type="HOGENOM" id="CLU_2873784_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="6988" checksum="8604BA115E5A93D3" modified="2013-05-29" version="1" fragment="single">MAGIFAAATTPLVLSRIESHQSHHSRTSRTSRYTDPWTEPLDDEISRLPSPAVSNAPTDPLSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7G2</accession>
    <name>M5G7G2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein SEC22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_92277</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633050.1">
        <property type="nucleotide sequence ID" value="XM_040777056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7G2"/>
    <dbReference type="STRING" id="1858805.M5G7G2"/>
    <dbReference type="GeneID" id="63692118"/>
    <dbReference type="HOGENOM" id="CLU_054453_4_1_1"/>
    <dbReference type="OMA" id="FIYWRFF"/>
    <dbReference type="OrthoDB" id="1719357at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15866">
        <property type="entry name" value="R-SNARE_SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000007">
        <property type="entry name" value="SNARE complex subunit SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="16">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="17">
        <location>
            <begin position="136"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU06156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="217" mass="24993" checksum="75E5D4BC8C0E5D9F" modified="2013-05-29" version="1">MVRSTTIARASDALPLAATVDDEQTEHTLQEYKQQAKLIFRRITPNSEPQCSIESGPYALHYLIADNVIYLTIAEKSYPRKLAFSYLDELAKEFSHSYGLKVDGVRKPYAFVGFDTFMQKTARLYQDTRNAGGGNNLERLNGELQDVTRIMTKNMEELLWRGDSLDKMSHLSSSLRDESQKYRKAARQINIDAMIRQWAPVAAITVIVIIFIWWRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7U1</accession>
    <name>M5G7U1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626740.1">
        <property type="nucleotide sequence ID" value="XM_040770393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7U1"/>
    <dbReference type="STRING" id="1858805.M5G7U1"/>
    <dbReference type="GeneID" id="63685455"/>
    <dbReference type="HOGENOM" id="CLU_829053_0_0_1"/>
    <dbReference type="OrthoDB" id="2552042at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="35389" checksum="91310F08D0159CE4" modified="2013-05-29" version="1">MSRNGQGHIFCCCAIPLLNTGIYLALLEQLSAGILIGTLILAAPPIVGVSIPSITAYIQAGLLYAVSLCQVLGFFGVARESTKLFRTYTYLNTLLVLSCFALAAALIGISASRHNTVVSACEAAFFPDTTQSSGLGAGALDGEGQSVCNIFAWVDIGLLGGLWLLLAIFQGYLLLINSFYARDQLADHKRYNSVYSPTDDILLSSHGAWDTRGSLEESRDLLSDGTGAGAGVGAGNAGLGAGAQYSDFQGHVRTLSETSTIRGEPFVPPTSPPRGGFGAGYGEGYGEGMPYPTMSGGIGQPEQEEQGYEQGYEQGYEQGQQGQRGPEVLEKFRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X5</accession>
    <name>M5G7X5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_105301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631129.1">
        <property type="nucleotide sequence ID" value="XM_040768070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7X5"/>
    <dbReference type="STRING" id="1858805.M5G7X5"/>
    <dbReference type="GeneID" id="63683132"/>
    <dbReference type="HOGENOM" id="CLU_010194_15_2_1"/>
    <dbReference type="OMA" id="ITAHVCD"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057571">
        <property type="entry name" value="SDR_PhqE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23441">
        <property type="entry name" value="SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="27265" checksum="A24AA2233474F9C5" modified="2013-05-29" version="1">MSIATEPSSPSLRQLVNKRIVVVGGSSGIGFAVAQSSLEQGAIVVIASSNEAKIQTAVQKLIQANNAFAGKIDGLVVDATQPDSIRALMDKIGKFDHLVWTAGDAVGMPNFLTDDLVAGAARPDLRLLAPAIAVQHVFNNKLFNEGGSVTLTTGYIAQKAIKGWTMAIAGAGSIVSFTRGLALEVAPIRVNAVAPGSVHTEMWEAASPQVVEYLKQSAINSSPLKHCGQPEECAEAYLFLMKCPMMTGSTVYVESGALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G855</accession>
    <name>M5G855_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STB6-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_40461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633290.1">
        <property type="nucleotide sequence ID" value="XM_040774481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G855"/>
    <dbReference type="STRING" id="1858805.M5G855"/>
    <dbReference type="GeneID" id="63689543"/>
    <dbReference type="HOGENOM" id="CLU_1485441_0_0_1"/>
    <dbReference type="OMA" id="HARGTIM"/>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="162" mass="17667" checksum="C8E92924B423E5F3" modified="2013-05-29" version="1" fragment="single">ARPMEHARGTIMVTSLATFRSDLNIVQIPGGVYASAKQDLAVNIDLSRLGCSGRRALTLEQPTQAAQDKFLQIYHLTPSTPFSLTVITLIKLVQSALFIFGCFPPAPELRDGLLCDITESGLQKWMAEIGEPVYDLEPSARILDDQVVAALLSSITAARQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8L6</accession>
    <name>M5G8L6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631414.1">
        <property type="nucleotide sequence ID" value="XM_040768112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8L6"/>
    <dbReference type="GeneID" id="63683174"/>
    <dbReference type="HOGENOM" id="CLU_433461_0_0_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="296"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="631" mass="68691" checksum="25A8F0333DFFDD7B" modified="2013-05-29" version="1">MLLRVYKMLRTTIGLPSVDRKVFPFRQRSVDTNALLKLAFTVFSTDPRITYSPASSWDLLREPGSTGPGSYFLLGPRNNGVVTFTFPQPSTTFQWWGWGYQRSDGDVAQICIDGGACQEYSYYNASTNGSENPRLLANIDGLSNSIHMIVMTNIEDQSVNAFGQMTVDRFILDNYEPSGGRYIVFSTDSEVIHSPSSSWSVLDEPGSAGCGTQFLLGARNNGVVKVTFPCSFFISSSCFIFTFWLRSVHSAAMVGVPTFRWRLGTAVDRFVLGGSILAPTFPSNTFISSVPLGFAYHAPMILGGNTPALEVLLDFGHPNVWVISDLCNSNNCAGHNKYVRGPGFQTLSIQDTAIYGNGGPDDTLVSWRVTDSVTWGDNTIAKTTFGASVEIPTSESLDGNFGMAKSAYAKCNGGEYNNFLENMYMQGDVVNAVIAFYQLDGSEGVPPGVSSEGSIGGLDANKFTGEVDWNQMNPQGQWESPACQRIVQASSFSSAIDATDLFNHPILLFDTGDPGLLTLPHDDWLILMSLLGAQGPDSNGNYLIPCESTMTWNFYGSQNRDYTFDLADTSSNNGNGFCNPLANDGGSIPTWVTGTPCFYKYYLAFHYTANMMGFAERNLGASAAESNPYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8P7</accession>
    <name>M5G8P7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">A1pp-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_47940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632013.1">
        <property type="nucleotide sequence ID" value="XM_040774794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8P7"/>
    <dbReference type="STRING" id="1858805.M5G8P7"/>
    <dbReference type="GeneID" id="63689856"/>
    <dbReference type="HOGENOM" id="CLU_046550_5_1_1"/>
    <dbReference type="OMA" id="AKWVIHT"/>
    <dbReference type="OrthoDB" id="6077599at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02908">
        <property type="entry name" value="Macro_OAADPr_deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF27">
        <property type="entry name" value="MACRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="193" mass="21084" checksum="8CC75C876F2B2C3C" modified="2013-05-29" version="1">MSSLSSPSAPVLLHCILYQHLDRQGDITRLQSDVIVSAAHRSLLGGGGVDGAIHRAAGEDLYDECLTLGGANTGEAKMTKGYNLPAKHVIHAVGPIYSDSQLDQKAQQLASCYRTSYELAAQNKLRSIAFPSISTGIYGYPIENATHIALDVTRKFLEHAEGDVRIVFVVFSDKDKYVYEELISEYFPPAPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9S5</accession>
    <name>M5G9S5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nuclease Le1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_104050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632458.1">
        <property type="nucleotide sequence ID" value="XM_040767871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9S5"/>
    <dbReference type="STRING" id="1858805.M5G9S5"/>
    <dbReference type="GeneID" id="63682933"/>
    <dbReference type="HOGENOM" id="CLU_044365_0_0_1"/>
    <dbReference type="OMA" id="GYRLANW"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067585" evidence="8">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="32804" checksum="CA466A73733F4CBC" modified="2013-05-29" version="1">MLAVSFLLTFSVLPRVLAWGNDGHETVGYIAQAFLTSGAASFVSEYLDSSYNGQLGPAATWADSVRYGTAYEWSQPYHFVDAMDSPLTGSCSVEETRDRDSEGCILTAIANYTKRITDTSLSKTQRDEALKFLTHFLGDVTQPLHCENYEYGGNDIDVTFNGDSDDLHSVWYTGIIELNLKTTYDNSVTTYANSLISRIKSGDLTSEAPSWITCVNPTEKLSSRASIDSLECPIEWARDSNAYDCSFVFTYTKRSDLAETSYYTDAIPIIDVQLAKGGYRLAAWLHTIFDGSTGLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V5</accession>
    <name>M5G9V5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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            <end position="252"/>
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    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="317" mass="35345" checksum="1A30DD36CC4CC243" modified="2013-05-29" version="1">MVNSTYWEECSSVSTFPTNPDITGIGNRIALYTSAIVTFLVTYNFPEDLDSYRDAVRTALVTSTSLIAAALYARYTPLGLSLVDAQIVTMFMTAVTACSWAVTKLNLGLTTRIAMRLHLILSGVFVILVYYDVDHFGGTAYQPQCGGNSEFFFVIFGRAISATNPVLRVFALLLYILMLAEFIWAGRGHFVLSVLDITSRICSREPFLGEIQALLSYVATGSKEGEQPENQRFVLPALASLLGVIIVIYLIITVEKMLSWNDLNTLTVVEQWTFGQTLAVLNLGDQIIRLGIKVIRRLRDTWRKSNKDINTDRDQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Z8</accession>
    <name>M5G9Z8_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <sequence length="241" mass="28267" checksum="1B60FB920F2B13DC" modified="2013-05-29" version="1">MHTFLQGLVKTLWYHNWVRGGHAKAAKYKIPPILLKVTDHVNTKIASNFLKLATVIKIYTHRQISETELDWADRLYKDFFEEYVEIYGEINVTPTFHWVTHMAAQVRCFGPAQGFWTFLFEHLNKVLKTIRTNRRKRGGVELTFAQEFKRELSISRLTTVLLTQWQDFLARLIAQEMDKQLRDLAHKGTLTSMAAEADEDADLHNRARWQPIGKPERVYLDNGTQQHLLAWYCEKMPNLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA89</accession>
    <name>M5GA89_DACPD</name>
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        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Stenlid J."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Tau138_eWH"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Sfc3/Tfc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
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    <dbReference type="InterPro" id="IPR035625">
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    </dbReference>
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        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20222">
        <property type="entry name" value="DUF6581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="B-block binding subunit of TFIIIC" evidence="7">
        <location>
            <begin position="176"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor tau subunit sfc3/Tfc3 C-terminal" evidence="8">
        <location>
            <begin position="1461"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="786"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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            <begin position="786"/>
            <end position="796"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20222"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="2061" mass="232633" checksum="956F1A3C22D0CCF2" modified="2013-05-29" version="1">MDELIKSCLREIAFDGDYGKLRVQSRVLVVLTNFCCDASRLKTFIEKFYCGNSKTRQNVDDGFRALVWTYIVQHPSVRVGFRPPSVTEDVFIADDIDRSRSKATRRQRYVNQGNRLAHEEGTSLPGLISLRPEEVEDSNLDQLLEKYGQDLRVAVDPEHCFQAITGSTLTPAKLTPMTYSTLQLVARARDKGITFVELSRITGYAAGAVFYLIKVLESAGLVKKFASISGTGIQMAVHIHFWLHHPDWQRIRAEEARDDVDRVSKLEPSGGDDMSVDDGTQQGLDEDIQDSSNLKFDPLDDRHLSRPDLIINRVNKLLEHSKNYCHKQFDVLLRIGLLNPTKVQRKRFSKIINAAVSQGLLERFHVPSRVERPGAPATARVLRLVPGEKRNLKYTAADETSGDADASADADEKEAEAHGQATHQSTRYLATLSLQRNLLNVVNAAGMQGITYVGIIRELGFSEQRMCEGQLQKLSKKANVLPHLSDLGIVLLTETIGRKRQLRLYTTHNFAILLKEEGFEDPDDDHPQEDLQYSGGFLVRSSGDFYRDDAELQKIVDHYDPKRFSDKYIRVIRPPRPGQPEKNRNPIGADGKPKKGRPRKYPEGESRASMARKRKLEEAAAAEITLPPKRQRTSRKSLVSVTPAEPSETGTESVLPESIQAPPVAPKERKKPGRKPKPKPERPTISSIETRPPVSPGSLDQGGLVGGVFATARRPHTRRWRSYEDETTASPSKRHVPAGGISAADLAPLLQLLPPLGPVIDQAGEEANSVDDISPLRTMEAEDLHSLTQTAPTSQDGKVLESPASRRRESAGNPKRLSVSYARRAQDIVEVLKRNHGVLHSGLPLQQAHKEYLTELESSGIRPAGSATTLDRRTISAVIDLLVHNKEVKVLTTDSGAYGQQNRVLKMLYLPDTPMEVVDRYRRSMEKQLKIFSMRKVPPTPLRMEYSEVGRQEKRTLRAQNELPEASSISDDIEVADSNYTIAGLSPIEVRHHILENEPHTVAQLYGLIPGIIWRARELYLFSLHHISVGPAEIDCVVSKPQRIVETKFFQSELPVATWCTLIPVNRYSAALEAYLHTTEGQESSLRNAPERIKRICGSYAVRGAKKLCKVLEILTALRMIQPLEVAERQKSEITCEPHSGYPATFCRRELGPLTTLPSYWQFCNQVPVYDYTQDPAPLLGVHGAGTMEECIDFWNNLEGISNDRQPVGLREDSKPPSFESSLHLQHEFLRRFKLPAGWRQMYRLSAYQQSCIRIMADEILTGSLQPELGIGWLQEISYALAAPVDAVQTYFEQIRRSRLARLNEKKLEHEQNLRRANLGESDSAKVLANKARQTKEILDNSWQALVKQTVETLVPGTFDLNAPELLQVKKNWHLRGGGMNVDNARDRIISAITGTAMPGIKKMQRRYYQPDRHGQLRDVPHCSLCESNLESIKSLVAQQEAEHQAYMSQQEDKRTVTQPRRRYTWTPEYDELALDAEAVIRARCAPEQQPAIHLLTQLFPRLSSNSVRTHALNLRKVRPGGDLYAAQLQAAWNALRLQPHADVPDPLPESLTHFPLEKHVAYLRAHLDKSKLGAALIDEALPPTDNMVYDLPNDMLYIETHWDVVTPKDTVKEWDFMWNTTTDEIRERNMHHEAFMRPRVAEDPLPPLSELNLTHRAETAVKMTVTPSEQDYEYEKATKMLELLGQIPVAVAYDNLKRDGVIKATAERKNASGRAMMVSDLQEEELEGQFDWRLFRDADLLERDLTHLELEPWSVMASDGRTAGILDLISSDLVELTVDTSSATALDIEIGSSSRGMITDEHLENNIYVIAKDKAPVLPSLGRASIMLEKQVADSRHAADNIRCSIGRGGVSNCPQCMNENFPRYLHNLGEPMRMQLCHLRQALREAGGAGLSVEDLQAFCFRSDSSFVHLRRALWDWCQGQVPIIACVGYDTGRIIAAEFLHEWCLQTSQLPFDMVLPRRWLHPSGKRDEALWQMSLRYVMGWIMTRTTISEAILRQRSSVLFDRLEMSSLLQYLVDEKFAVRRTAMQESTPVLIGFSTNEEEAVWHWDMGPVPWYLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA6</accession>
    <name>M5GAA6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PAN2-PAN3 deadenylation complex catalytic subunit PAN2</fullName>
            <ecNumber evidence="9">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Poly(A)-nuclease deadenylation complex subunit 2</fullName>
            <shortName evidence="9">PAN deadenylation complex subunit 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PAN2</name>
        <name evidence="11" type="ORF">DACRYDRAFT_46547</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 2 metal cations per subunit in the catalytic exonuclease domain.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Positively regulated by the regulatory subunit PAN3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C19 family. PAN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="9"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA6"/>
    <dbReference type="STRING" id="1858805.M5GAA6"/>
    <dbReference type="HOGENOM" id="CLU_002369_1_0_1"/>
    <dbReference type="OMA" id="TQELLWT"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06143">
        <property type="entry name" value="PAN2_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000028">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03182">
        <property type="entry name" value="PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030843">
        <property type="entry name" value="PAN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028881">
        <property type="entry name" value="PAN2_UCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13423">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="463"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="868"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="870"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="977"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1030"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1093" mass="121168" checksum="D612A86DB87A2F98" modified="2013-05-29" version="1">MSTYHTISPLSLSPEPVSALAFDPFSDTLWSGSESGIISCYNGIEPSNVRYPLVSNPLPPAGIKRILVTDREIRSFSSAGVGGRSRGGISRWFYRCEPHLWSMLPLSAFANHPTSSTGALLATASAVQELSLPAETISRQIPTTAPVTQMRTSSSGLLVTGATDGYLRTYDVRHPRGHVYSSADVKAHNGAVHCLETSGNFTFSVGLNMRQGRPYPEPLVKLYDLRNLRPLSPIPFSAPAFLNVNPNRPTMLFVTSSTGLIHNVDIGNPNDSGEFYQLDIASYLTASAISSNGTYVGFGDAEGLVHLITSTANDERVPFNGPNGVPGEAPDATEPLPEIHWDNSTPLNMVGMPYYNTPLLSRLTTTFAPEFESFYPPPKIPVQVLSSMKIVDFVGWASLPRDLRGRRNVVAKKDDIKQGKFKSERARRGGADIPKHYRRVDIEYSHFGVEDFDFERYNRTPYSGLETHILNCYSNALLQMLFFSDCIRKVALSHIASPCPREQCLLCEVGFLCKNLDDAKGVNCHSGNFCKSLSTFPQGQSNALGLVESDYQDNTTDYGTLIQTFQRFLLDQMAVESDKKPDKNPALCKDLRGEPLTTPSISQLTGLNTTTVATCMQCRATSTKEGVSHAIDLVYPRKGLSTEPSPANDFESILSSSLSRNMTYKATCPTCRNVTISGSRRVLRGRSLPPILAINAAAQSADNAAYWADGRKGERFLTSTVTAKMESILEEGGDVIQVEVEYELRGIIVQVKSDKETSHLVALMKVPDSQAREPTESPWYIFNDFCVHNIPESDALGFPGPWKVPTILWFERIDTDAVVDLSTLPMNVDAHILTEDICLSWHRDPKKIMHEIFTWNEIPTPGTLVAIDTEFVQMQKEEVEARSDQFRKVLRPNQFALARVSVVRGDGPKEGVPFIDDYVQVSESVYDYVTQFSGIEPGDLDPSVSKHTVVPLKTVYQKIRLLVDLGCIFVGHGLAQDWRIINMFVPPDQVIDTVSLYHLRKRARKISLRFLAWFLLKGNIQTGNHDSIEDARTALMLYKAYMVMEGEGKFDELLDRLATEGRELVCHKGSVFVDTADVISRTSKCLKKLQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAT2</accession>
    <name>M5GAT2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_116872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627935.1">
        <property type="nucleotide sequence ID" value="XM_040770278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAT2"/>
    <dbReference type="GeneID" id="63685340"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OMA" id="WIGGIQI"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="265"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="49263" checksum="405E3D576DE03653" modified="2013-05-29" version="1">MSDHEKPSSREAIGVSRTNTLIGAESNDLESGPQIILDPGKEDLGVVQTVHVIPDGGLKAWSTVLGSWLVMIATFGYMASFGVFQAFYVEDLLPNYSASEIAWIGGIQIFLLFSMSIVSGRLFDAHKFRATMLVGSVLHIGCCFALSAAQPGQYYQYFLSQGVGQGLAMGLMYLPSVAVLAHHFAKKRALVIGIVFTGSALGGVIFPILVNNIFQKNGFRWGVRAAGFLLLGLLALANLLMRPHYNPAHKKMAKPSILKLLQDRVYTFSMLSALCSGWGLFFPFFYLELYATSHGIDQTIALYTIAITNAGSILGRVVPNVFADRFGPITCQIPSQFVSAALIFALFGIKDQGSLIAFSVLYGVFSGAVFSLFAPMLAVMADSMAEVGIRMGLAFFVMGVAGLTGTPINGALIGSGPNYSWWKAIVFSGTTLLTGACLMTLTRYLFQQKRQKRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB99</accession>
    <name>M5GB99_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein bS18m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_60818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633093.1">
        <property type="nucleotide sequence ID" value="XM_040775650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB99"/>
    <dbReference type="STRING" id="1858805.M5GB99"/>
    <dbReference type="GeneID" id="63690712"/>
    <dbReference type="HOGENOM" id="CLU_110814_1_0_1"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="198" mass="22649" checksum="432C9629ACAE30AE" modified="2013-05-29" version="1">MFPFVIPRLPSLPRSVVAGPSFARRFGAFSPTCVRRYAPTTQPEQGAEQGDAYERLASSLDSQSADVEAVLTMERTRRFFPDKAYAPWSQSVDNREFSGRQRKSRRILGPSKKVAMQVDPFQLNQIDPLDEYRNIQLLNEYVTETGRIVRRAQSLLTWRSQRRMGKAIRRAKAMGLIPVWSKVKNERMMVGPSVTLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBU5</accession>
    <name>M5GBU5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628390.1">
        <property type="nucleotide sequence ID" value="XM_040768577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="63683639"/>
    <dbReference type="HOGENOM" id="CLU_262390_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="802"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1289" mass="142987" checksum="B588C07773AFCA7E" modified="2013-05-29" version="1">MDNNTDPQPHTPPPSSRVIPRTPGNRSLGVTVDCGRIGTLTVHGSKGAIVSIFPVDHKVTRIGGDVSCHVRLYDSDAPRFVCDLRFDVNTHKVHIDARHPSCMRNNVPVYRSAIKAPLEDGERISLPGHKFTWHYAAGVKLLTKQMLDMSQPGLRGFRLSIFPSSRVFPATPTEHRKRKHVKLPEFLAPAHSSKKLQKKIVSHVVESPSAAPSTPAPRSRRGYRAPDDSLDSMSGDTSVDSATSSVYDSDSSMHFGLAQDGNRFIALEEVDEATEPKGARTPAPVQKQINNRLMRRTRAVFSIKRVKQYVEWQGNQTPRPGRKLHFLDTAEVNIIPNNLEEHQNDQDEASFPWPTDGVQFPLEDLTDAYVDVPQDQLKLSTQGLGTSNGVEISENVVGIPSEQHEPVLSSLPSTPTRPSTRLAGRNPRFPKQNTPKQSLLALALMNACCHREQEERIKEDRERERLRQEAENRSDRQPQQHMWEDWTLFLQQQQSWGLNQMVANNWFPPFATMQQTVPTSLNDGPIGAPPIIFSLSTSEESSTQPAYYGQDSRDLQSTYFNSMPLLGGSSDQTSIYPTQPTFPSQYNPTMPSEQLIPMRFDDTAHAWQTLSEEEYEDIPMDLDPPVELQLDPQLMDHIYGLELGMPPVQAMPGTQQHADPVDQPPLTIFPEQDPIFTSLQHIHEASVPSYPTQLSLVQEQNHLSQTGRARLEATHRSLRGSGTNSLLSPPNRRPRWRPYWSFTPAQREKGKKILHRRLDRQRAQAQKSSVLKPLDEAGDHLATDPDLLADVDEAKTQNAVTPDVFRVLTQDSSPSETTEPPQMSVNTDLEPDKLEKSGPIVQISTPTLSDELAPTQSDAPTTNVVSQTTMAEPEPDLTPDPATSEEVQQELNADAPASSPCDVRVDKILETGDMVVQERSVVVEQEKPARRSKRKLQDSVAPVDTAPAKKASRTNTRRKAQEVVLDAAPSIEPAKEISVADVNTNNIGASRPTKPLRRTRKNAVADVPEAPPRRRIARSTAVKPAPKAELTAEPPEHSTGEVIAQDTLMPIGPVNMDGHQDVQTVTEGQEPTVMEGPTPVEKPQFVEERPIRSLRSSRAAKSAVQSVPEPVTNTRSTRRSKKAAEPVVEQQSRDENTAPKQLATPAIVIVEKTTAEEPARVTRKRRRVVEADEADAKAAEETKELVVKSGGRKMALRERKAIEVHSPKRQRTSNFVDAAEEQQPVQPAKRTRKARTVATVTATIDRELPPSPVKRTRSRVTRSGASQETAVSKVAAPLAVVKKSRALRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBY1</accession>
    <name>M5GBY1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_102925</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632859.1">
        <property type="nucleotide sequence ID" value="XM_040767686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBY1"/>
    <dbReference type="STRING" id="1858805.M5GBY1"/>
    <dbReference type="GeneID" id="63682748"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="IQPAFRL"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="533" mass="59865" checksum="D02471A662865DA5" modified="2013-05-29" version="1">MELLHPYSVFDVVAVSVCASLVFAMIRRLFLRSKVTILSGPKRPNWLWGYNRMLISGTSGDYFEDWQKQYGDVYRIPTAAGAERTVIMDSRAIGYILNTNAYNFVRHEGNRRSIRRMLGGGILTVEGKCFQAINVNYSHHEHRKAMSPGFTIASIRFFTTIFTDATHKVREQWLAKMADSKDKEIVLDIEHWMNAISFESIGEAGFSHDFDCINDEVSTIGTAFTSLGSTSGNLASAIVLALVQAFPIVASLPLARNKAMDNLHFLMQDVAKSVTKERKTMSSEVSDDRRSLVASIIKAENRNLSEDEVIAQINTLLLAGFETTSTTMAWCLHELSINPRVQNKLREEIMRFPAATHEQLATQMPYLNAVVQETLRTHPAVVENHRVTMKDDSIPLQRPIKLANGKTVDHIEVSAGMGLIIPIEAMNKSSAFWGPDSHEFKPERWLENELPKKVTEIQGFHHLLTFIDGPRNCIGKNFAVAEFKAAMSVIISSFAFAPLTDGSDIQRVRTLVQRVRNKGYDGLLLRVSRVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCA4</accession>
    <name>M5GCA4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628560.1">
        <property type="nucleotide sequence ID" value="XM_040772929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCA4"/>
    <dbReference type="GeneID" id="63687991"/>
    <dbReference type="HOGENOM" id="CLU_2263635_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11452" checksum="A54A4F19C8A0C452" modified="2013-05-29" version="1">MPWCAYEVEHRPRCEVRGARCKVYVEECRGAKLKSSKTRVARTNAVVQTRNRASSNRDRTTKSIHPGRSLSQATEDVEDVSKTGSPALTQCDTTPLGRTLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCA7</accession>
    <name>M5GCA7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_21221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630656.1">
        <property type="nucleotide sequence ID" value="XM_040772298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCA7"/>
    <dbReference type="STRING" id="1858805.M5GCA7"/>
    <dbReference type="GeneID" id="63687360"/>
    <dbReference type="HOGENOM" id="CLU_097982_3_0_1"/>
    <dbReference type="OMA" id="ASKYSYW"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00917">
        <property type="entry name" value="PG-PI_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.220.10:FF:000004">
        <property type="entry name" value="Related to phosphatidylglycerol/phosphatidylinositol transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.220.10">
        <property type="entry name" value="Ganglioside GM2 activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036846">
        <property type="entry name" value="GM2-AP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033917">
        <property type="entry name" value="ML_PG-PI_TP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067724" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="40"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="18107" checksum="939020B9C7C03C92" modified="2013-05-29" version="1">MFVRTLITLSALAATTFGSILPQLPLFNDGDVTAQAGWTWSDCGDPSFAIEVQSIEVTPDPPVPGKNMTVDVVGTARSSIEDGSFAEVTVKLGMIQLLKKQFDVCMEAQKANVTVQCPVEAGHYAISKTVTLPREIPRTKFIVNVRGSTQDDVDMICLDLSVNFGSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCT3</accession>
    <name>M5GCT3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_44414</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633304.1">
        <property type="nucleotide sequence ID" value="XM_040774572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCT3"/>
    <dbReference type="STRING" id="1858805.M5GCT3"/>
    <dbReference type="GeneID" id="63689634"/>
    <dbReference type="HOGENOM" id="CLU_054274_1_0_1"/>
    <dbReference type="OMA" id="DGIVWDC"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="128"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="38070" checksum="CADD240BC3F9E9D4" modified="2013-05-29" version="1">MSLRSASKLVFRCFKSMEKAGDWLTGAAGPVFISFAWVLMSGGAVVFFGTIAPRLPFIILTLPICILIAANLFGHYYLACTVSPGYADSRTAPVPGWGWAPKRSKPLRLGKGWGNGRLGDRLLRSRSRERRCKKCGGMRPERAHHCRICKKDVLKYDHHCPLGINQCVGLGNERHFVLFMAYFVLACFCFCSLGYSYVWLSLNYFELWPYFPGRVAFILIYILAGVLSLAVLTMLLWQLRLISVGETTVENYDNDAYRRMTRSRGEPFVNCFDLGWRRNLWLFFNLDEYPIYALMLPLRVMPYTAGHTWAKRPGYERHGGVDDGDEMTDEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCT4</accession>
    <name>M5GCT4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628855.1">
        <property type="nucleotide sequence ID" value="XM_040771147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCT4"/>
    <dbReference type="GeneID" id="63686209"/>
    <dbReference type="HOGENOM" id="CLU_806585_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="344" mass="39406" checksum="B3059C506871AE3E" modified="2013-05-29" version="1">MPMASWDDKSLNNLQVRLNLLCGLHGKDASPINSFECKLDEEIILVRQKIESLRGWPVDPDGNPFPTQTSPTSSYLSTPPALPLGAPHSLPPLTPDSSPLTKRSSCAHYNSVSSVDKEDIENLKKHICELEKERPCHKKKKNLPLVTDLKDDKLDKSDLKLKKHLQDELQEFLYSKVGYVKDGIMPSKNGPQVEGTPKIPDFDKSLHYHDNVLICNSAVQLLMDQEEGPTAFCQEEFYCNCWIIVPVLNKLAHQAWWNMKAIYSKQEVAKIDGGVKEAALKRAGWQYEWCRNTGMLSQAEQEDPNLDIYKVCCPEWMNQKYWEWEKLLLHKKILRRETKHIDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCU8</accession>
    <name>M5GCU8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Protein transport protein BOS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_93519</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">SNARE required for protein transport between the ER and the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 11">Belongs to the BOS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630966.1">
        <property type="nucleotide sequence ID" value="XM_040777163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCU8"/>
    <dbReference type="STRING" id="1858805.M5GCU8"/>
    <dbReference type="GeneID" id="63692225"/>
    <dbReference type="HOGENOM" id="CLU_078260_1_0_1"/>
    <dbReference type="OMA" id="FCWLVIH"/>
    <dbReference type="OrthoDB" id="158360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15863">
        <property type="entry name" value="SNARE_GS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR028865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="249" mass="28019" checksum="CAF1F795AC594F2D" modified="2013-05-29" version="1">MNSLYTLGIRQTSSIQTDLNKLRAGDSSTSLQGQISASLAALSRTVDDYDSMAKREMIAAKQEKAFSRVHKFRQDHAELRTQFDTLKKEAANARARENRNELFGSTTSIPLSPGMGPSIMTARQRSFAAGPSQPPEWMEESPFSLRPAVQSSASMRESHALREQSFIESTENQLDQFLMQGKEVLDNLVDQKNLLKGTKKRLLDAANTLGLSRDVISWVERRTTQDIVIFFVGAIVTLVCFYYIWVWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCW3</accession>
    <name>M5GCW3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_79701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628905.1">
        <property type="nucleotide sequence ID" value="XM_040776410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCW3"/>
    <dbReference type="STRING" id="1858805.M5GCW3"/>
    <dbReference type="GeneID" id="63691472"/>
    <dbReference type="HOGENOM" id="CLU_068529_0_1_1"/>
    <dbReference type="OMA" id="CRCIQPV"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="96"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="265" mass="30641" checksum="A6866A32CE857D88" modified="2013-05-29" version="1">MLAQVVRCKPLRTVRAPLPRVLSTFAILRQAHVLQLHHRHLSTTLTLFLPRDRHPTHLHNLLTNKYGFCPSCEAPYLLALPICAECGNIGVLPPRVNYFDLFELEKDPRRGAFDLDEKILKQMYLGMQKICHPDAWSTKSEEERKRAEDISSILNTAYSTLLTPLSRAQYILSQKGIDLMETDSLGQDHSEFLAQVLETRELLEGPLNFQELEAIRTRNDDRATYTVERLSQLFREGNWEQAREDAITLRYWQGIEDAVKERLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD82</accession>
    <name>M5GD82_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_114684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631231.1">
        <property type="nucleotide sequence ID" value="XM_040769860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD82"/>
    <dbReference type="STRING" id="1858805.M5GD82"/>
    <dbReference type="GeneID" id="63684922"/>
    <dbReference type="HOGENOM" id="CLU_005843_0_0_1"/>
    <dbReference type="OMA" id="YWIASYL"/>
    <dbReference type="OrthoDB" id="341486at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16691">
        <property type="entry name" value="mRING-H2-C3H3C2_Mio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21720">
        <property type="entry name" value="MIOS_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="6">
        <location>
            <begin position="596"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="476"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1111" mass="123139" checksum="AB8B759DAD10662B" modified="2013-05-29" version="1">MFSSASDKVQGTRRLDQVIWDPRGTDRFIVGGGTDVKMYEWAPDEGKIKLVTVQTDLQYMKALAWSPSPNFNDLVAVGLSTGRVELMRLNAGNATAAGRRNHVDASRTVSLSPKAQRSCHALAFSAVDPNYLAVGLDKVRNESSLIIFDVQHSSSSLGTSSPVPSSGSRPQPALNHRGTGSAFKGETPALQAYASAELVHSIAWVPYTHTSILAGMSQKSIRLYDLRDNITATGYSQFWNTKWSNGLCFDPFDSFLFASYGEDSRVCVWDRRKPVEPVLYLDDMDAREGSRPRTISALAWSPTHRGTLVSLARDSTALRIWNIATSDRVVEEKPLLDEGKRERPRSHSVASVASTADNSVSGSSGISSQNHLILISMKKSAMVSYPITSFAFVPHGSPNNSSPHVVTLGKEGRNIDVRPLTSFCQHIWGSRGHLAIGSECVLRILQPVESTDPVAHVPMVLGEAIRVTSPVVVNGNAARDNKDARRGITRTSSRTHLRPSMLSGRSDSPASVPQLSVSRSAASPTRDTDGTATPRPALRALPSTSTIAADPAPARRLTLASSQPQQVQHAHENQTTRKQSSSTMERVLTGDLSSTMLHRAKVGYGLENARDNANIIGEDADGDSEYLHDLWMWIEEHHSALIGESSPENIRMLGFDFSVHGVMGIWDGFDGAKSPSETPYSATEASQYPFPQRSESPYDAHRGDFDEAISRLVSLSRLDNKQMTHLAPTKHKNRRLLALSLSGWCLSDEELFRSMHNWEETGQHAKAACWSLFTHNVDRAVDILMRSGDEQSRAFSAAVAGFDDQRDKDPDRIIDPRTQRWRDQCEKLIVRTQDPYLRTLLQYMVTDGWLDVLDEQSLPLKDRLGIAFMFLHDDQISSWLHRLSRRKGSKGHIDALLITGLTAPGLDLLQAYVDFHGDVQTAAILGTLASPSLRSDARIDRWVEAYHDLLDRWKLFHERCQFDIERGRMIQDAIEQHQLESYEWTERQIMVRCHFCAKIINPDAPPSIPQPGKEERPLVNFCPSCRNKLPNCSICLVPVGMPSDFVRDAGLRMDDQLRDTLDIGMVFCMTCRHGGHAAHILDWFHGTGRTDGKGHEVCAVADCTCRCADQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDH7</accession>
    <name>M5GDH7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Receptor-activated Ca2+-permeable cation channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_66519</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629302.1">
        <property type="nucleotide sequence ID" value="XM_040775818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDH7"/>
    <dbReference type="STRING" id="1858805.M5GDH7"/>
    <dbReference type="GeneID" id="63690880"/>
    <dbReference type="HOGENOM" id="CLU_009570_1_0_1"/>
    <dbReference type="OMA" id="MTMFAAL"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="249"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="746" mass="83984" checksum="867504AF948E6807" modified="2013-05-29" version="1">MRSSEDLEDANIPLLGSPIAIEPEERGAIQVFPLLQRIRKDIEESIDAALSWTQLNAPDVNFAIVRPLVFKYEQLNNSAIIYCFLLVRWHFVTLSESDLAYAGVNSSRAALCELLATKLVRGLSHRPMELASALTASWSVLQGASVPALAQIGLAVGGKPQELEEPMNALEMGIFSQAKFFMSSPLVQGVVNEIWSGRVLYSSSSDRSLVADNYKTRFIQIYDARVAPFLDHYRLRVPRYRALLEFLNYVLLLGLLCLCLANRNLQHINIYEAIFVIFAFGMVLDEYASSQEHGWKIYAANMWNTFDLTWVLMFLVYVGFRVRSLWLHDDQAADTAFDVLACSCVVLFPRVAFFLVANSVIILALRSMIKEYVFFISICMICFSGLLFTLWRLGDHKWRLSQIAWLMVQVWFGNTFLSFSQAESFHPIIGPVLMVIFAASVGLISTILISILSNTFARLNEYATEEFLFQFAISTLEGVKSDALFSYQPPFNLLAYFVLWPLSHLLSPRALHTINVFLIRVTALHILVTIAVYERYFAPRSSFLESRRTSGWKNVFLPRHFKKIAFVEAFIGSNNNDLLKAVFQVVAPPGEVISSDDEEDDHPEDIPIIRVPSPNPETPKSPTFPLQPSAPFPSLLRTPSTRSPSPAPDRGRRRVPSQTGTAYSPLAKLFNRGSSVESDDRRGVLDANALIEASKRMERTVEAMRVLPVTKLADEVRELQERQARIESLLLSLTRGMRGEGRGSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE54</accession>
    <name>M5GE54_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TFIIF medium subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TFIIF-beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_98779</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631986.1">
        <property type="nucleotide sequence ID" value="XM_040777547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE54"/>
    <dbReference type="STRING" id="1858805.M5GE54"/>
    <dbReference type="GeneID" id="63692609"/>
    <dbReference type="HOGENOM" id="CLU_047858_0_0_1"/>
    <dbReference type="OMA" id="PIADNCY"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000035">
        <property type="entry name" value="General transcription factor IIF subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="12">
        <location>
            <begin position="50"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="11">
        <location>
            <begin position="230"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00081473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="37620" checksum="4F0D960C08A19170" modified="2013-05-29" version="1">MDMETDAGPSTLDMDSLDPKREDDLLDYEGAESDDSFEPDEEMDAAEGEEKVWMVKLPKFLMEKWTAIEQEDVVLGTLRVYHAPDPNGNQRLVLRLPEMTDPAVYDITTLPKQYSLKMQRKTVENEFVMASKMKERERNIISTKLEGKIVHDCHAFPIMDASYTSLVASRHREANAPKRQTKVLEDEGGALHRINMLAGGAGENLGTGFGNFVSTEKKAAVASSAFERAARMPRNELMDLLFPLFRSNDNWSIRDLRNRTRQPEAYLREVLQEIGFLHRTGTFANMWSLLPAYKGRAAASTGEVPEIKAEGEGDMEMLEEDDEDDFDMEEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEA2</accession>
    <name>M5GEA2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_113393</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632106.1">
        <property type="nucleotide sequence ID" value="XM_040769621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEA2"/>
    <dbReference type="STRING" id="1858805.M5GEA2"/>
    <dbReference type="GeneID" id="63684683"/>
    <dbReference type="HOGENOM" id="CLU_002865_7_2_1"/>
    <dbReference type="OMA" id="EIMPMAY"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF219">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="632"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="657" mass="71668" checksum="77761C2161FC04B0" modified="2013-05-29" version="1">MAEQRAASTSYALFLAMLWRWLNWIWLYLPFVRFLSDAPYPEQRPEDVGLPLKIREEDVSVQDLPGEEDAEGVWDYIVGGGGTSGCALASRLSETPGIRVLLLERGPVGDNFLSRVPLISTNFARANSPNYRWLPQSSMLDQGSEGKGGKKGGKADMAMVSGKVLGGTSRINSMLYTRGAGEWEAMARAGRKGWSFNDVYPYFLKSERALGPMSLRPGHGLTGLWQTRAYGHYLLPSYNPCVSAAQSVGLPFIKDLNAPQRAPYGVGDVDVSMDDKGRRCSAYSAFVPAELVLERKDRFAVCTETLARKIVFQDTDQGPRAVGLVIEDEDEERAKEKGRFVVRARREVILCGGAIGSPQLLQLSGVGPAEFLKEKGVKVVKDLPGVGEHLQDHFGASVQYLTPLTHSFHALEHAFYAIRHILHYILFGAGIFLAPIVQISIFTKSSTISPVDGRCTASKLIGESALNPENVPDVEIMPIPAGLSVPPPPGQGGFSFLTVLATPFSFGRVRLASTDPRQRPACDLGVLSDERDWAVIRVGLKLSLALAGEMKSQGYALKDQCVLPMDANEEEVKAFVRRQGRTTYHYSSTCRMAPEAGDGDGPGVVDDELRVHGVLGLRVADASIFPKILSVHLQAPCVMVGEKCADMIKKSWGDLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEC0</accession>
    <name>M5GEC0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_45890</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)</text>
            <dbReference type="Rhea" id="RHEA:67920"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 19">Preautophagosomal structure membrane</location>
            <topology evidence="3 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the ATG9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632166.1">
        <property type="nucleotide sequence ID" value="XM_040774668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEC0"/>
    <dbReference type="STRING" id="1858805.M5GEC0"/>
    <dbReference type="GeneID" id="63689730"/>
    <dbReference type="HOGENOM" id="CLU_006200_3_1_1"/>
    <dbReference type="OMA" id="DEHTVWC"/>
    <dbReference type="OrthoDB" id="2020634at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0072">Autophagy</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 19" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU05272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="574" mass="65364" checksum="FB49C89950BB55D3" modified="2013-05-29" version="1">MIEPAPQPVKTSRRSKKSASRTSSNGLPLPAPVTHAGGPSVGKAGLDAREMALWNWVNVQNLDAYLQEVYAYYVGKGIYTIALTRGLNLLTVGFVIFFSTFLLACIDYSSIHNHTSLSNVIIPQCISRFSGWTFLFFVAFGAFYAWQCVSYVYGIVRLVHMYRFYTHVLDVPDADIQTISWPAIVARISKIRESNALTAAALSSSMAGSKMVQKLDAHDIANRIMRQENYLIALFNKDLLNLSLPLSRLPLPSFLRNYSRTGAGTLTRALEWNLRFCVMEFFCDPSGHPRKVFLKERNRTVLIEGLKRRFIFMGIINAVFAPFIVLYLLMYSFFRYFEEYHKNPSSIGGRQYTPLAQWKFREFNELPHLFTRRMHQSYPFATEYISQFPSSKVAAIMRFVSFVAGAFAAVLLLATVINPDVFLGFEITPHRTVLFYLGLFGSVLAVSRGMVPDERTVFDPELLMRDVVEFTHYMPAEWQDQLHSKTIHTEFGKLYEMKITIFVQELVSVILTPFILWFSLPACAPAIIDFFREFTVHVDGLGYVCSFAVFDFKRHGNVNVSPTSVPCYLLLANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEJ5</accession>
    <name>M5GEJ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EI24-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_103960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632366.1">
        <property type="nucleotide sequence ID" value="XM_040767852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEJ5"/>
    <dbReference type="GeneID" id="63682914"/>
    <dbReference type="HOGENOM" id="CLU_046461_0_0_1"/>
    <dbReference type="OMA" id="CWVDSYY"/>
    <dbReference type="OrthoDB" id="266518at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389:SF0">
        <property type="entry name" value="ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389">
        <property type="entry name" value="P53 INDUCED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45792" checksum="FB299C061B82CF73" modified="2013-05-29" version="1">MSSPATRRPARLRPQPSSSSSSSPAPRSPSFLPSGLSQPSNAQRLPSRPSHPSHLSHSSHPSYGPGNASTYAYTDYPRFLTLWETASLHASWALHGLWDAFRWDHVFRFIQEPEIQKNVLKSLLLNGLSLISIFTFEWLLLPLLPHNPSYQRNLGTAYQVLWLWPVVGASLWFNSIWSTTIARKAFLLQHGQAPVPDTPSYGGVLNSIASSAYRLIFLLSYLFLQLCLAYLPVMGKPAGFVFTCWVNSYYSFEFVNIARGLTLSERIKQHEERWAYYLFFGLPSAALCMWGSSLANAASYALLFPAYNIMSMPAHPLPRHPYAPHPSPSAGGQPALLSPYIPIRIPVFTPVILVNEVVVRALSVGTRTRRGTGGRPAAGSPVRGKRWGTQAMELTEEGTEVDTFRPRRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEL0</accession>
    <name>M5GEL0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAIB/BAIF family enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_74736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632401.1">
        <property type="nucleotide sequence ID" value="XM_040776084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEL0"/>
    <dbReference type="STRING" id="1858805.M5GEL0"/>
    <dbReference type="GeneID" id="63691146"/>
    <dbReference type="HOGENOM" id="CLU_033975_0_0_1"/>
    <dbReference type="OMA" id="IIAGPYC"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047369">
        <property type="term" value="F:succinate-hydroxymethylglutarate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="456" mass="49826" checksum="C411726BEA1951F1" modified="2013-05-29" version="1">MAILLRGAVSSRWWCGSLLTARAAKVRNASCRYNSSISAASLHSVSSGIPPPLKGIKIVDLTRVLAGPTATMLLADLGADVIKIEEPVKGDDTRAWSPPFAPIPDGSPKPDLPPESAYFLCVNRNKRSCGINFKQSEGLEIVRKLIKDADILVENYLTGKLVEMGLGWDECHKINPRLIYCSITGYGQTGPYRKAAGYDVVIEGEAGLMHITGERDRPPCKVGVAVTDVSTGLYAHGAILAALLSRQQTGKGVWIDCSLFDTQIAGLANIASNYLIANKEASRHGTQHPSIVPYQVFPCKDGFVMVGAGNDRQFKILAEQILERPELAEDERFITNGLRVQNRVVLCGLIADCLMEETRDYWLAKFDGLGVPFGPINNIQQTFEHPQAVARGITAEVEHPRAGNIKLVAPAVHYNGARMPISRPPPYLSQHTEEILQELGYSQQAIQELHEKKIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF05</accession>
    <name>M5GF05_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_77446</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630612.1">
        <property type="nucleotide sequence ID" value="XM_040776273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF05"/>
    <dbReference type="STRING" id="1858805.M5GF05"/>
    <dbReference type="GeneID" id="63691335"/>
    <dbReference type="HOGENOM" id="CLU_020178_2_1_1"/>
    <dbReference type="OMA" id="WTMVNLR"/>
    <dbReference type="OrthoDB" id="2140105at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF1">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="3">
        <location>
            <begin position="87"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="536" mass="59057" checksum="6F1BC4A456D7F119" modified="2013-05-29" version="1">MTSNGTSESPKLLRRSTTVHSTPAFNPQSPPKPRRLHLLPPPSHHGPAATNPYGTNQHGIQKYHHGFFDPSLAPLRAAYMKIMGMMTIVIVLILWACLPLYWGSFWLELTHSPGLNAWVVNRDPNGLIGQFVTQAMVNSSHGMWDPIPEGHLGWQVVSPSQAGSDQDIEDAVAVHETVWVVLVIQENATAILEEARANGDPSYDPTKVLTWYFSEARNEIATDTIIQELIDYILGLTSARLNTLLAAEYLQQIQGNVTALANLAQAPQTISGPVSITMVNLRPYTDPTALAVELVGSIYLIIVAFIWSNGHAQARMLISPHLRTRSYLILRIVAPLISYLPLSLAFSMISLPFKLPFDGKYSYAGGFFLYWCYCYLAMCALGLAIEAMITLLTPRFAFLFLIPWIITNVSVAQTPFELGAWFYRYGYGFPVFNLAQAVRTILFNTRNALGLNAAVLLSWAGLSLITMPTFTLLMRSLEMRKARKEIREANVARKENVDVDVGYEGGGTLAQEDTASDSDVVERGGKVANGGSLTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFE1</accession>
    <name>M5GFE1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_73520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633081.1">
        <property type="nucleotide sequence ID" value="XM_040776009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFE1"/>
    <dbReference type="STRING" id="1858805.M5GFE1"/>
    <dbReference type="GeneID" id="63691071"/>
    <dbReference type="HOGENOM" id="CLU_019532_2_0_1"/>
    <dbReference type="OMA" id="GPILKVN"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="463" mass="51007" checksum="F0081D547BB9AFBB" modified="2013-05-29" version="1">MVSTKVTASKAVAFLNGSPTPFHAVRNASARLEEAGFTRIRETDQWELKPGGRYYYTREQRSLIAFTLPQGWKAGTGVSIVATHTDSPNLRIRPVSNKTSSGYLQVAVETYGGGLWHTWFDRDLSVAGRVVVATPGTTQFQTKLVKVERPLIRIPNLAIHLDRTINDQFKFNKETEFIPFLGVLSEELNKMPEPKYEEKGPQIKPAPSERHHPALLAVLAEEMSCAPEEINDFELALYDTNPSTVGGLQNEFVFSPRLDNLMSTFCALEAICESVTLEKKTDNVNCIAMFDHEEIGSASGVGAQGSLLPSFLSRLSPTPEQHAHSVARSMLISADMTHAFHPSYASKYQDGHRTMINGGMVIKTNANQRYATEAIGAWVVRRLAARRGGAIQDYEGRNDMPCGSTVGPLLSQLGLRTVDVGAPMWSMHSVRETCGAHDVPAAVNLFLALFEGWRDEVGELMVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFX3</accession>
    <name>M5GFX3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_74194</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633546.1">
        <property type="nucleotide sequence ID" value="XM_040776054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFX3"/>
    <dbReference type="STRING" id="1858805.M5GFX3"/>
    <dbReference type="GeneID" id="63691116"/>
    <dbReference type="HOGENOM" id="CLU_004969_2_0_1"/>
    <dbReference type="OMA" id="RFWTSQP"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="84"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="255"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="738"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="856"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1161" mass="133089" checksum="EEC643C9D9B38041" modified="2013-05-29" version="1">MRTEDDEPEQAASDDDAGEAQAGPSGSQEEDPVVKTDEDDDESLSRRKRARLDKEGSSRVSKEEKLVRREPSVRDRDGYVPGSIVRIALENFMTYDSTEFRPCPYLNMVLGPNGTGKSSIASAIAIGLGFSPSLLGRSSSVHSYVKHGAESGWIEIELKGKPGQGNLIIRRGLVSNNDSSTYLLNGKNVPAKAVKDAVEELNVQVANLCAFLPQDRVSEFAQLTPEKLLIETQKAAGAAGLTRWHEQLIDMGKDRRKITEETDELKKDAEYLEQRNSVLERDVARFRERREIEKQIALLELQIPFAAYAQEKAKYDELKEERNRQSRVLAPLLERNDPLNVFKAEQEERKRKVETKKKKMEDEARKMYSATKKLHEESMKLADKADEKRSRVAIIRKNEKERKERIKKLKAEIARYEQILADPPDFQTPLEENKQKRRALQDELPGFNEEKAKYQQRYRAFEEEKAVFVAEKERASELLKELDNRSEVRLRNLERFDKDCADAVRWLRTNLDKFEMEVVEPAIISLTVPDNKYLDAVESCFNVNQLKTFVCQTEQDFKTLNQLVNDTDRALGRKARINTWHRPRNQAKLLPPPLSLEEVQHFGFDGYAINFVEAPDAMHWYLRRELNMHRTLIGLDASQIDNRAAADAVSAQIPGQTGTVPPATFIAGRVSYTVSRSAYGKRLVQQQTRDLRPGRNLNNVAVDQNYKNELIEKRAMATQSLTDMEATDVELQQEDQRIKGMEKGIKDRKDELDREREKIKQNEAAFRSHGSKLTIVKNKLLGEENAPSADQERSELRAELLENARERTRLGIGYTNGMAELIEKYADVTELGLESMQLASNIAYLVQLGSEQGEARKEAEAAYREIDEQFKRCKQRATDFLNTSRAKLKEADDDIKDAFQQNKDAGGSIDLDDLEQQLEAERARFQLNMAVNPSLIRKYEEQKAEAERKRRLIAEKERSQGKYTKKIKGTEEKWLPALEQLIFNINEKFSDAFARVQCVGEVKIGKDEHDYAKWRIEIWVKFRDNEQLQLLTAHRQSGGERALCTILYLMSLTELARAPFSLVDEINQGMDQRYERAVHNNLVEVTCAEGAMQYFLITPKLLPDLKYHKRMRILCVNNGEWLTGPQNSDKWGNMRKMLHHARYYPLGKKSASLASPVIAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFZ2</accession>
    <name>M5GFZ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631477.1">
        <property type="nucleotide sequence ID" value="XM_040771871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFZ2"/>
    <dbReference type="GeneID" id="63686933"/>
    <dbReference type="HOGENOM" id="CLU_650563_0_0_1"/>
    <dbReference type="OrthoDB" id="3359330at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="46260" checksum="DF02E154802457A5" modified="2013-05-29" version="1">MAVAVASVVPFPCSDSPAEYRAPLALPLFPAPPVRVRRDSGVMVAPAAFSVHRMHGVSSKEMNAMSKTGHDESTKEDILPQDAEPQPASIIVSRKRSTRDDEDEDEQDVREERETKKRRVASGITLVDLKINVVVPPIEPKTAPIVEFEPTAVDDAETAEFDRQIEEIEKQIAEAMQKLESAESHTSSRSAPPACSVSPSSPPVVSGGNRPVRPSPLKAFAVTKPHVQLSKMASVESPVARLSSPPPSLIVPPSLPSPAVDRQANGGKSTRGGANSSAPLRRSRRLSSLPPLTTKVRRVSPPPRDSLYRQVLINQMRIASMADDFGSPSFSPPTPTTSLPSTNDDDVDMERVDTHANTVTPTPEPIDPRLFPRQGCLKQMKAEHERRRMEKEFDCELAWFAAKLQWEMMNKKTGNNRRDRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFZ5</accession>
    <name>M5GFZ5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631492.1">
        <property type="nucleotide sequence ID" value="XM_040767934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFZ5"/>
    <dbReference type="GeneID" id="63682996"/>
    <dbReference type="HOGENOM" id="CLU_062464_0_0_1"/>
    <dbReference type="OrthoDB" id="5415522at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="376" mass="41868" checksum="A6E1AC353A25305F" modified="2013-05-29" version="1">MAKQLTTIHNTDLPRWQVSMETADAHWAHTPRTGNLWSRFVKMVEQEGKEVNPHLNKGPGIRCSMDRRYYIPDLNVWTWLHDNCLHADVKGWQKGNAAAFYEIAMNLFRTKLKFNKFIDKHQLSCASVPHWSMTTRFHKAVSLNADGVRVWSPIGVAKEFITSGLDELKIDVLVGYFGHRRQKAELGRAYRNNILDENGVRALSLVDQHDKSRWTEVFQSAIVPPPAEGLPPLGLEPEGLKWSDNHTVPAAGPSHMDTAIEDETLLDYGDSDGYDRACYYTSSGTNSQGNDCEAPLPPPPIPSHPIPSTPPIPVTPSIPPASRAYQTRRNGSSYSHNFDGSTHYDFGRGYERSTSSDGQVAEFFFSGGGKGASSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGL3</accession>
    <name>M5GGL3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_113744</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SPC24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632582.1">
        <property type="nucleotide sequence ID" value="XM_040769692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGL3"/>
    <dbReference type="STRING" id="1858805.M5GGL3"/>
    <dbReference type="GeneID" id="63684754"/>
    <dbReference type="HOGENOM" id="CLU_108108_1_0_1"/>
    <dbReference type="OMA" id="AQCTSHF"/>
    <dbReference type="OrthoDB" id="3344830at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013252">
        <property type="entry name" value="Ndc80_Spc24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08286">
        <property type="entry name" value="Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="21886" checksum="1FD3D80F2EB225F2" modified="2013-05-29" version="1">MAPSATVQEHIDVISQVISLVDYHADLRTVKNATERMKARQTAREREAEDSRAALRALSRQLESSRAAATRPSTVPSQAAHSESLIQADATKFQLAKSINDEEGSVAQKEAEVGRLREELVRLEAWDPEGEWEVDSYAMRLKVMHDLGFEFVPGVEGRLLIRSDKDRTLHSYDYDPAKSKVQNVNEIWRLAGLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGV1</accession>
    <name>M5GGV1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_112899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633022.1">
        <property type="nucleotide sequence ID" value="XM_040769530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGV1"/>
    <dbReference type="STRING" id="1858805.M5GGV1"/>
    <dbReference type="GeneID" id="63684592"/>
    <dbReference type="HOGENOM" id="CLU_021993_6_0_1"/>
    <dbReference type="OMA" id="YHINFAI"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="54"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="441" mass="47763" checksum="1B761FC06D55D134" modified="2013-05-29" version="1">MTSIELADRIHLDSLRSGTSLTNRASALEDVPAEPQAEAVSAVPTLSRRQEWTYLAVLYWAYFVYGWNDGSTGPLLLRIQDNYNVTSTIVSLLFVGTFIGYVFSAALTVPLMDTFGFGKICSLTALCQVAAYALMASALPFPAMVSAFVLNGFAVGLLGAQANVLVTNLPNSENKHQLLHASYGVGATVSPLVATLFSQTVHWSFQYLITACFALLVFVLVTFVFRLRRMEDVLGIPEGANAEEQANRANKFQQLLTFKAVHLLAFFLLFYEGLEATIGGWIVTYLTQVRGAGPSAGYISSGFWRGLTVGRLALMWVNKKIDPRRVIFFYLGLAIAMEALVCFVPWVIGDAIAIAGVGLVLGPFFPLVVGTGSQLLPRWLLAGSIGWIASVGQVGSALFPFLTGLLSQKFGIKVLQPLLVAMMASCIGLWALVPAIPRRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH47</accession>
    <name>M5GH47_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633502.1">
        <property type="nucleotide sequence ID" value="XM_040767777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH47"/>
    <dbReference type="STRING" id="1858805.M5GH47"/>
    <dbReference type="GeneID" id="63682839"/>
    <dbReference type="HOGENOM" id="CLU_674424_0_0_1"/>
    <dbReference type="OMA" id="WIGASNG"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="45191" checksum="767B31EDD437AE8D" modified="2013-05-29" version="1">MINAFDRPGHTFIPRQSPLEFQVDPSSCSLMGPTAIVVQLFMGALVLLSLVYKRQRERPMRAWRIWAFDVGKQVIGQATVHVTNIIISWIGASNGTETNACSWYLVNILVDTTIGVGLIYVALHGLTNVLSERLRIPGLVSGEYGNPPQWSFFFRQLVVYLFSLAFMKVIVLGLFALVPEIMRLGDWMLEWTASNWALQVILVMGIVPITMNVIQFWLIDSIVMSKIIPFASNPVPVTDDLHEPLMYDDVPERDFDDEGATLTGKRILDDLEAQRGNGNEGKVRAPTTTRSPPPTDRRSSSTTESYNLRPISRENSNHAGSSTNAGFKVPKLHLTKPSGDWQTKGNADWEWNAQDEWGEDPFDGEAQGSKDVKANGLGKKGAAAVQDTDDAADDAWESMDGLDGPKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMZ2</accession>
    <name>M5FMZ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_25628</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623438.1">
        <property type="nucleotide sequence ID" value="XM_040774245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMZ2"/>
    <dbReference type="STRING" id="1858805.M5FMZ2"/>
    <dbReference type="GeneID" id="63689307"/>
    <dbReference type="HOGENOM" id="CLU_022195_0_2_1"/>
    <dbReference type="OMA" id="TFGMGKH"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="443" mass="50860" checksum="7CF724CBCDA95948" modified="2013-05-29" version="1">MMIEGHTKFKGKPFQLPTFRSWMVFVSRELFDDIRKARDEGLSFKEQVNEAIAVEYTIGKALADDPWHVSVIRKQMTQNLGAKFPEIYEEISQAFADELKFPNSGDWMPVNAYELILRVVCRTSNRLFVGLPLCRNEEFTKMSCDYTTTVIRAGFFIAMFPGFLKPLVARWLSAAPAATKGFERFLLPVIEERIRKEEELGESWNDQKPFDFLQWMIDAADGKRREPKELNKRMLAMNFTATHTSSMSFTHAFYWLAAYPQYVPELRQEIEFAIKEHGWTRDAIDNMFKADSFIKEAMRLTGLGVMSMARKSMRPFTLSDGTVIPTGSRIAVNAWSIHHDPDTYEKPEEFDPFRFSRRIEQGESIIKNAFTTSSSSFVFWGAGTHVCAGRYFASQELKAMLAYVVMNFDVKMPNDGERPADVWFGAACIPDPKATVLFRKRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN01</accession>
    <name>M5FN01_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623483.1">
        <property type="nucleotide sequence ID" value="XM_040771436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN01"/>
    <dbReference type="GeneID" id="63686498"/>
    <dbReference type="HOGENOM" id="CLU_365628_0_0_1"/>
    <dbReference type="OrthoDB" id="3363095at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="763" mass="86911" checksum="F3426E0A8166DA13" modified="2013-05-29" version="1">MLRAYLRRASAHIQCNTCQLSYYSHSIPQTVHSNALESIKQFVLGHPTTQEEDVDLRSVFNVNPPPAPTNQQPHTAHLRPHQLSPSLPRNASTAATLAPPSSHPLLDHSAADWRTWADRLADPAHSASLAPEEIEHLLIALTLNWSTQARAVRLLKRLVIRRSAEELRRILSWKAVERIVHAGEKSSAHQLLAVLVQIVLRLYWPHRDTSVHFPLRWESNVPRMEPVLDHFIPPKGKERPPAYETAHSEPDISPPTLSREEKHLASRVLTHVLEIYFHRHLYLEVTRFHAQLLSLGLTPDITSFNRVLQSHFRWFLYPDMYRSKRNSVTFQQLTESVRHTLDQMREYDITANSSTRSILIYGLVRCILFSPLPELHTRWGSIAPVITRLPSHAEGDIMLRLTWTEACLELAELRARKDAHVQYKLGREVTRTELEATQEEWFHQSLGAMQRFLLVSGSNSNSNSNSNSNSSARSYTQLTLFQLTYELRICALNMRAALVDADIPSAAYWLQLLRPGYEHALQRLALPENHNWGFLRADIQQRFEASTVRFVSYALERGALTDALGALNWGKYIRHPSTLLMLWRRVLCFQPTENLRWEDRGVGVGEALESLMRTLDAHPKLGPKSPLKRSSGLKGIYLVQVNEKLVAYHLWAALLGSAPGDSLLRALRFPDAGRGKRLDFLRKVFDRCGVTPSAKFWSAQGSFVEFCRGKHVEEVGQEELDWVRRVYEGRRGDAPALADGDGEGEGRGGTFRFFGVKFNVKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN24</accession>
    <name>M5FN24_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623598.1">
        <property type="nucleotide sequence ID" value="XM_040770892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN24"/>
    <dbReference type="STRING" id="1858805.M5FN24"/>
    <dbReference type="GeneID" id="63685954"/>
    <dbReference type="HOGENOM" id="CLU_506241_0_0_1"/>
    <dbReference type="OMA" id="THAIEIM"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="65"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="578" mass="66682" checksum="5F06617208148CF5" modified="2013-05-29" version="1">MARGVKRSRAQVESAEEPTLAKSKKRSHTLNHALTDDAGDPVSGKSAGVVNPQKAKKVRGRRGQLAFILQAPTEIVLQIMSHLWPLDILNLSYADKELRSMLTAPNNKFIWEAARANVPGLPELPPDFTEWGYARLLWFNECDMCGSRLTRKPEFALLRIRLCPKCSKKHVINGFHLHWPRDIIKPFGDHTALLPNFVGDFFEPALKRLARRVQKIKGTPRWEVWEKQRRTFIEKVQEHGKALSEWIVETNLAAKEKSIQMQMRRREAISERLIGLGHSPEDVASILMQKQRLICSSEEVTEKNWPRIQKILEGVLRNIKEERIKATREDEIRDSLKRVYCEYWASLPPGKDKHTMPPVLDFLDLPSSLRLLYRHDASGVDMKASFSNSIAQIEQDIELFRSVLRRDLFLMYDTYERQQSFAAWAKDDTNKNDFTRYRFLRRATTVFVFSQGRVGTPVHYDSLFSHAFEPDHTRGQTPNLLAKWDDLKQMLRVDTHAIEIMERIVKRAKLNPATTTIDDLESLGAGFSRPNIDKHDHPITWRELVCPSAIDVIRADLLLAKYHELMTLQCSWVISADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN42</accession>
    <name>M5FN42_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_60032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623688.1">
        <property type="nucleotide sequence ID" value="XM_040775607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN42"/>
    <dbReference type="GeneID" id="63690669"/>
    <dbReference type="HOGENOM" id="CLU_1986821_0_0_1"/>
    <dbReference type="OMA" id="IRTWALW"/>
    <dbReference type="OrthoDB" id="2638860at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="14511" checksum="77BD8CB0C572F982" modified="2013-05-29" version="1" fragment="single">YDYLLMFPKERRYIWGAKWTPGKILFVLVRYMPFIDLPLWPFDAFLANLPLDCDVATYITIIGLVIACVLADVVYGLRTWALWSRNRYVGWFLLFAGVAFNGTAIIFLVVIQPNVPGKGNVVDRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNC0</accession>
    <name>M5FNC0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1479-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_18895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624078.1">
        <property type="nucleotide sequence ID" value="XM_040771404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNC0"/>
    <dbReference type="STRING" id="1858805.M5FNC0"/>
    <dbReference type="GeneID" id="63686466"/>
    <dbReference type="HOGENOM" id="CLU_011148_0_0_1"/>
    <dbReference type="OMA" id="PWDLTGR"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="40759" checksum="847ACAE365C88AC7" modified="2013-05-29" version="1">MGDVPLNRAERLAEADKPTFDAEYGTPLKRSIVSPSDEAALKACWVDLINALAEAQKEIVAKGPTIIPQIESGDLDKLSEAQRDEIRKVGSVVVHNIVDDDLALKWKGMLREYIKANPQVDGFPEEDKQFLQMYWAKSQVQARSHPKVIAVQKALNEFWTRPKDDNLLISFSTPLTYADRFRIRTARMWDRHPPHIDGAKIERWADDSLRSCFASVLKGDWRAHDPFVVDGRIRAESNMHKRPGQSSMFRSWQGWLAMSNTGPGEGTLKVFPNVQWSNAYVVLRPFFRLRSAELDPLLAENWDYDPDTAHYPGLKPTKSIQLTEDTHPHLQTETTMTCMPRVLLGDMVFWHCGACFGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNL1</accession>
    <name>M5FNL1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624533.1">
        <property type="nucleotide sequence ID" value="XM_040771369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNL1"/>
    <dbReference type="GeneID" id="63686431"/>
    <dbReference type="HOGENOM" id="CLU_440768_0_0_1"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067123" description="Alpha-type protein kinase domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="68274" checksum="6594DA54D6930418" modified="2013-05-29" version="1">MNQKLAHSAILLLVHRVSQLAQRLGQSCLRGSKKYTGRLLVPSVQSMKFSNIPGMPAYGANTRPTLLGYNSNHGMYPQQHQLVKMAVSAPWAEVMRVDTSMQHLVEGKNRAKQLGNTSKWLTNVPATLVPTELKQYIFTQLHCKIQQDMYHFLFQLDYFELCGLGLADLEKDPTCSALYQQCVKTHVKNSISMQVFMPNHLVEAFLVIEKEVWPAVSLWIEGSTEGLSHSNVIILGFPSVSGPDVSTKVAGHTGVMGAVTAGLGGGSSAIKQPLISQMPPCPTKHMVWELGRSPDNAAVDHALRASDYSKVTKANGASTYVIHYSTFTNGDSVKSIMAHGLFLPMPMISWNELISGSVKLVINYKGDRCHSVLQVNKDLKKMLGPPRMFKMAHSALLTLNEFSVKWEEKQPFALGHPTKVAAKHYYVCSKPRGSCHQVKMSVELMFLQDKVNLLYWVTALHGLVKYFVEDYITLNPNSRACTLELPDTCMVLGGLFQYGQDSPQECAGLVTLIEEKYQKMFKKAFVLDYQGEHRQLHKCNEYCVAFKLEPLHDPNVCPEPGGVPAKSLNLPDVEDIIKDTLAPSPVEGGGVAGKDGEHTGDEPGMQSLGGPHATGTRGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNT9</accession>
    <name>M5FNT9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624818.1">
        <property type="nucleotide sequence ID" value="XM_040773878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNT9"/>
    <dbReference type="GeneID" id="63688940"/>
    <dbReference type="HOGENOM" id="CLU_891428_0_0_1"/>
    <dbReference type="OrthoDB" id="10655864at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="312" mass="33781" checksum="8E54B39A8D7971EF" modified="2013-05-29" version="1">MSNLSRAHTHPTTRPLTSLSELPPPHPQRKSRTAAPTPTRSPPTRSPQLRAIPRSALASPLEEREEDPFGVAGFYGPAAAESFGWVREEGRTQPGEGDDGEEKRLDGEEELGMDECVRRVLSMEDRMGVLGISLPQLSRTPSSGSPSPPRQPPTTYAYTTTTTSNAYTYAYHSSDAPYPETDDGLHESFAARTKAMSYPDLVMLASKRAPSSTVPAGLSARGRKGMASLSPRPAPVSQTRTRAEVIYTTERRESSLERRTAVTSTMGVEPELGGLFFDGLGEKQGQGVGVEGAREGWRVWALDRAAKVVGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP47</accession>
    <name>M5FP47_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_18265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625103.1">
        <property type="nucleotide sequence ID" value="XM_040771349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP47"/>
    <dbReference type="STRING" id="1858805.M5FP47"/>
    <dbReference type="GeneID" id="63686411"/>
    <dbReference type="HOGENOM" id="CLU_001832_5_11_1"/>
    <dbReference type="OMA" id="FHEVMET"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000145">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="168"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="579" mass="64513" checksum="AB0C58CDF16946EA" modified="2013-05-29" version="1">MPPTVGNQGTGPAHGVLIVVGQTGCGKTTQLPQYLFETGWAGDSKVIACTQPRRVAATSVAMRVAEEVGCVLGEEVGYTIRFEDMSDPEKTRIKIRRKRPSLRLIISSATLDAQYFYDYFTSMPGDTPSTTAQPDEAVIISLEGRMYPVEVGYLREPVSDYVREAAETVKRVHVREGAGDVLVFLTGREEIDRCLDMIGEWIPTMPDSALRLTPLPLHAGLPFEEQQRIFDSPLPGTRKVIISTNIAEASVTIDGIRFVVDSGFVKLRSYDARSGISRLVTTPVSRASALQRAGRAGRTSKGVCYRLYTEEAYNGLRKTTPPELVRTDLALPVLQLKSLGIDNLNKFEWPTPPPAENLVRALEWLVMCGAIDNEGRMTQEGDRMGEIALDLRMAKCLLASGEFKCGEEMLTIAAVTSVQDLFIIPEGQAGALAELERRKFTAQEGGRSSSSFCRAHALNFRALSRAMSIRAQLKKYFLRWKIPLVSCEGDSARLRKCLIAGYWRNAARIMPDGTWRGVRQDTVLQCHPSSVLFTRRPPSGWVIYHEVEETRTTNIRVLTEIDPDWLLEYGYTLVDKRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPX7</accession>
    <name>M5FPX7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_90880</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625743.1">
        <property type="nucleotide sequence ID" value="XM_040776981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPX7"/>
    <dbReference type="STRING" id="1858805.M5FPX7"/>
    <dbReference type="GeneID" id="63692043"/>
    <dbReference type="HOGENOM" id="CLU_013528_3_1_1"/>
    <dbReference type="OMA" id="FHNDMKS"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1910:FF:000005">
        <property type="entry name" value="Cysteine-tRNA ligase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="37"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="688"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="759"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="782" mass="88674" checksum="DBA101B445A4B7C3" modified="2013-05-29" version="1">MADTKVRQAEWIRPTPIVEEPRLKIYNSLTREKTEFIPIRGRQVKWYNCGPTVYEASHMGHARNYVTQDILRRILSDYFGYDVFFVMNITDIDDKIIIRSRQNYLLEQLKAKSTSLTTSLIAEVREAWQQYRSGKLATVPNPAETAWPDIFQQFTARDPWALQALQQDEKVSMHMAALQSAYAGLEQADKVIKRNDTTPSNATELIEAARDVLSLYLDKLHGSSVTDPAIPRAHAAHWEDQFLKDMDRLRVMPPDALTRVTDYVQEIAIFVQRVVKRGWAYEAGSSVWFDTAAFDHAKTQRPDDWEHVYAKLEPWSKNNKKLLEEGEGSLTSTSGKRSASDFALWKASKPGEPSWPSPWGPGRPGWHIECSVMASEVLGEQMDLHSGGIDLAFPHHDNEMAQSEAYHDCRQWVNYFLHTGHLHIEGLKMSKSLKNFITIDDALRVNTARQLRLTFLLQPWNGKMDYKEALVQEARSVETAINNFFTLIKALIAESNVALTAGDRGHGYHEEEKELVAQLQTAQHEFRVALCDSFNTQAAMATIQDIISKTNIYYSKKKSAANISVMRVVALWGTKMLRMFGLGEGNQAGPGGGIGWGEAATGEVDNVDRDSLLMPYLRVLSTFRDDVRKTAIGHGTPKDFLTLCDKLRDEDLVPLGVALDDQEGDRALVKLVNPEILMRARDEKAAAAAEKKRAKAAQQEAQRQQRIAKLERGRLAPNEMFKPPHVPEGTYGSWDEEGLPLTEGEGQELSKNKVKTNKKRWDEQKKMHEEWKKWQEEEGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ93</accession>
    <name>M5FQ93_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ARF/SAR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_118319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625928.1">
        <property type="nucleotide sequence ID" value="XM_040770561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ93"/>
    <dbReference type="STRING" id="1858805.M5FQ93"/>
    <dbReference type="GeneID" id="63685623"/>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="OMA" id="FTCWDLG"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001166">
        <property type="entry name" value="ADP-ribosylation factor D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067048" evidence="7">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="20003" checksum="C7C1B403E493A4F0" modified="2013-05-29" version="1">MGLTFSSLWARLFGAAELKILILGLDNAGKTTILYRVTMGQAIETAPTVGSNTEIFEYKNLKFALWDIGGQSSIRSQWAQYFIATKAVILVVDSTDPARLHVSREELHRICADETLRDALLLVFANKQDVPGAMTAARVSDGLALTELRDRQWQIVPCSAITGQGLFEGFDWLVTRLEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQL0</accession>
    <name>M5FQL0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_112365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavoredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623937.1">
        <property type="nucleotide sequence ID" value="XM_040769400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQL0"/>
    <dbReference type="GeneID" id="63684462"/>
    <dbReference type="HOGENOM" id="CLU_059021_3_0_1"/>
    <dbReference type="OMA" id="KSPNPNW"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798:SF5">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798">
        <property type="entry name" value="FLAVOPROTEIN OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="63"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="269" mass="29718" checksum="A72D65C86026F8F6" modified="2013-05-29" version="1">MSLPPFNESFAPRYTESPNPSWQYGDKVGGITAAQQWLEGEKQGWTSLDTSVETSKLYPMMISGIVPRPVAFVSSISETGVENLAPFSFFNMVAFDPPAIIISCSNKPRIKDTCHNIRTTKGFTVNIISEPFVENANVTAVDCPEGVSEWDVSGLTRVSSVLVKPARVKESAFSMECELLDAHNITNPSTGIASNTLIIGWVKHIHVRNDVLNERGVVDPTKLRPVVRVGDISYARLGDVFRLTRHVWEKEKEKMQGSAQKDLAESAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP1</accession>
    <name>M5FQP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623977.1">
        <property type="nucleotide sequence ID" value="XM_040774062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQP1"/>
    <dbReference type="GeneID" id="63689124"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_2_1"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF3">
        <property type="entry name" value="CHAIN DEHYDROGENASE (ATSC), PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="27745" checksum="1B7834CDB4DBAD93" modified="2013-05-29" version="1">MLTYVVTGANRGLGFGFARQLAEEGNKVFATARDVESAADLAALPGVTVVQLETTDPESCKKAAQTVAELCGGAVDVLIANAGYNGVGAFYELGTFPSDAVLMAEVESAYKTNVLGNILTINAFLPLVQRGRKKTVVALSSGMADLKFQEDLGYSGNAVYGASKAALNYVIGKYAIRHKDEGMIFVALCPGWVRTSGPEDEPYSKEALAPFIKMLQQVEPTCSGPKSLRNGTDACLNVIKRLTVEHNGQLLSYHGDKKWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP3</accession>
    <name>M5FQP3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">DACRYDRAFT_23857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQP3"/>
    <dbReference type="STRING" id="1858805.M5FQP3"/>
    <dbReference type="HOGENOM" id="CLU_034595_0_0_1"/>
    <dbReference type="OMA" id="ICQGDHF"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="212"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="32497" checksum="CB4AA1DC8257524B" modified="2013-05-29" version="1">MATTTEIIGKSWADDVDEPIIQHPRVEETVDENGIYTVVEYTTNEEGKKIKITRKIRKMLKTSVVDHAVAERKHWTKFGIEKGNKAGPDRATTTVSEPIELKLQAGGVKQAEPEQDDAAAMKAKLGNKKVVCRICQGDHFTARCPYKETLEPMGLGAPGAETPMDGADTPQNEPAAAAPTTGGKYVPPSMRAGASRGGESMYKAGGSREDMPTLRVTNLSEDAEEDDLRDLFQRFGRVARVFIGRDRETGVGKGYAFVSFEDRDSAQRALDRVHGMGYANLILSVQWSVPREQRAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQR6</accession>
    <name>M5FQR6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_119105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624806.1">
        <property type="nucleotide sequence ID" value="XM_040770724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQR6"/>
    <dbReference type="STRING" id="1858805.M5FQR6"/>
    <dbReference type="GeneID" id="63685786"/>
    <dbReference type="HOGENOM" id="CLU_043966_2_1_1"/>
    <dbReference type="OMA" id="QYEFQMW"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="6"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="25700" checksum="C451EAFF0B957D81" modified="2013-05-29" version="1">MMNLPPLTMIVAATQANGIGISRTNTLPWRLPREMAYFARITSAAPEGKMNAVVMGRNTWESIPEKFRPLKGRWNVVLSSREMPHLIGIPNTVHLASLSDLGSVQPPKPIYRFFIIGGAALYKSLISHPSFDRILMTRVVSPDYEECDVFFPDILESSEALPGAAKQQSEAPAPEDTGKASQPARWTKASHAELQAWAAVPVPEGIQEEKGTKYDCQMWVYRWYVTVFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR04</accession>
    <name>M5FR04_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_59367</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624147.1">
        <property type="nucleotide sequence ID" value="XM_040775557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR04"/>
    <dbReference type="STRING" id="1858805.M5FR04"/>
    <dbReference type="GeneID" id="63690619"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="CFVMELM"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000196">
        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF6">
        <property type="entry name" value="MAP KINASE KINASE MKK1_SSP32-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="46"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="38339" checksum="13CABE76A2653214" modified="2013-05-29" version="1">MSGASSISSLADAIKEWTIHPVESDGSDSESAIGETTDKVYSDADFEVISRLGEGAGGSVDKVREIATGLIWARKTIPAPSAPVQQLRRELNFLSNCKHPHIVVFHGAYLSANDSLINVLMEYCEGGSLEAVRDRMREERARMSEKVIAKIAEGCLKGLQYLKSKNIIHRDIKPSNILLTVAGVPKLIDFGVSGELVDSYAGTFTGTSYYMAPERIQGAKYSVKSDVWSLGLTLMELARSEPIYPVDLGPIELITYIVSSKPPSLDDGDWSDDMKDFFNQWQAHFLYPSHQSLTGIVNSLAVDPANRPSPTELLHHPWIVESSKRKINLARWIQQVWQWDSSSDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR22</accession>
    <name>M5FR22_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_109594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626388.1">
        <property type="nucleotide sequence ID" value="XM_040768909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR22"/>
    <dbReference type="GeneID" id="63683971"/>
    <dbReference type="HOGENOM" id="CLU_005027_3_2_1"/>
    <dbReference type="OMA" id="AYPEWWI"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF118">
        <property type="entry name" value="BETA-1,2-XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="428"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="704" mass="80700" checksum="0231DC02BC6379F2" modified="2013-05-29" version="1">MLRNPLLPLRSTQRQTHKHSLSITSRRRHSYLSAARTFSLHIWRRIPLSLRVVLALICVLAFGAVLWKGEDLPSVKVKHRLGFGRNRASTEGEAGAQREVLIPARSPPGTTLRERPPNPGLPPPAGERPPRPKRPARRDPPPHPPSIPPRPGSFPSHQFLPSGLMRVNPNGRHPIYDLVEFGERQWRERMDRQSSTLAEAVGEYKRRWGRRPPRGFDSWWAYVQKHNVQLPDEYDQIMLSLEPFLAHSPADLRRLQASTRELPGTYTIVASPSTGRLELATSNFPESEQDLGVLRAREQLELMRGFGESWVDDQGERTSVEREIVSATGRWEATFSIGEPRVVGDWEMGRERREKSQRREYMNLFRKPVHDLGWPEACSPNSALRLSFPDPPELPARPQSPKTFIFDHQASMSPCSNPSLIHLSGTFLSPPEGEGKNRLLFSVSKTELHEDVLYVPSQTWDEDSELEWEEKTDERLLWRGSTTSGILVSPELAWNASQRIRLVSLLNTHDSSAWPVLLPRGAGERVGQPEERRQAWMNNLFSDAHFTREPVHCRLGGCETLGESFDFRRPLTAEKERTHKYVLDIDGNGASDQFGQLMRSKSLLLKASVFGEWWTGRIQPWVHYVPVQLDLSDLYDIMTFFRGDVGQGGRGEHDVLARKIAYAGREWSERFWRKEDVVAYTWRLLLEYGRVVSDDRNDMNFEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR52</accession>
    <name>M5FR52_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_101224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626443.1">
        <property type="nucleotide sequence ID" value="XM_040767538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR52"/>
    <dbReference type="GeneID" id="63682600"/>
    <dbReference type="HOGENOM" id="CLU_553231_0_0_1"/>
    <dbReference type="OrthoDB" id="3051727at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="493" mass="54692" checksum="63892870286487B1" modified="2013-05-29" version="1">MSSLFHWNRKSTRSHKSNSSGSTLVGSDGRVSPTSTYSSKKLKVSSFDMVVLPDGNIVRVQGEGKIVPDQPQRWETVLAVAKETLHVLRGIGVQACGAGDLAAKVYGATCIPAEIDLFILTDKVDYTQVLRRLIHHNPKYFIIPLTPALRNLTPSSLDATTALQQALYYRTSSTPIRINLQLPPTPLILYLTTADITWHASFPLMPLPLVLLDKLRAWVLNCYIPAGREASLAERRRLWAEHADIEVLMGQVARARVNLRRERLCAHAFKRDRRPGLPVPEEEEELEVERWVREYITVYPEGRAMWAVLGVRIFDPPTPATTVYGLSRTGTRSSNSTGSNGSSAPPYPSTPPLPAQYFPRPSFSSDQMSLRSRPSLQHSSRSHTPIPESPMTPLSPADIPLPMSPESVAVDRTYSRASTPSRAATPSRFLVREPRSPSSRPPLPPMPPIPPPSGLAGTVVQQLRSKSPFGRKKSSRTLGKERGKEESYFDWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRL7</accession>
    <name>M5FRL7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">IMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624542.1">
        <property type="nucleotide sequence ID" value="XM_040770762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRL7"/>
    <dbReference type="STRING" id="1858805.M5FRL7"/>
    <dbReference type="GeneID" id="63685824"/>
    <dbReference type="HOGENOM" id="CLU_470104_0_0_1"/>
    <dbReference type="OrthoDB" id="5594612at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037470">
        <property type="entry name" value="IVY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407:SF1">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="61981" checksum="F98F23E3A233034A" modified="2013-05-29" version="1">MSIPRPSLSTSYGRPPSPTLSHRSQSTVSVAADFAGAPSRIISKKGLRASLAAYDELITAGRAYRLSLAQISKARESFALAIERCARLKGVSDESSGFLAASGLHYLIANQEQVLGDTMLKMFEEPLAQGLEAYRVKVTDRQITYDRSLTELSLQIRATEAANIRHGLKRQRDLTSFRTALSTLQAQVDALDRLKAEYYTSVLSFEEETWDTVLSRVGHVVRSTLDIYERVSAKGSDLALEPILARDPDPFNAYGEPQENKLFSILTPLGMISPSLTTVGGFGRSEGGRHGVPGGERQAEMEPEAEGTPARAPQPAWGHHSPADLDRPHWGEPDSPRGFYPRLSGYSASSAIAEADPHAVSGNGVPGEAEGQGERESPRRKEKRSRLGRIDEQFERGRKGPELAEAGESTSTPTPMPASTSARATGVPGSRTPVSGAELDARDQLVGKGIREGAESAEPEGSTTTEAIATEDLDSPQAASPSAQESTTVPEPLPSTRDAARPATNPYFPDLDSLRDVGELEAVPVDGNPKPGRGAQAPGVGEGEGDKAVDAGDKAEELGEERLMEEPAPWEGNDARADGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSK3</accession>
    <name>M5FSK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625067.1">
        <property type="nucleotide sequence ID" value="XM_040773783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSK3"/>
    <dbReference type="GeneID" id="63688845"/>
    <dbReference type="HOGENOM" id="CLU_1015720_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="31725" checksum="451FDFCC855805A2" modified="2013-05-29" version="1">MPKLVKYVVATGAWMERAFEFFAAPRLRWLEMDTERCEIPSYTFDAPVYEFLEVSKPPVETFVVRHISAFVLHLLRQLPTVRQIAFLNAEADYGAAYKQVLDGMTQSIFNLEAKAPICPQLESWCTDLPLDESHLLKLLDFATARNEHGWRIERIMFKPLFHWDMKFYPPPSSTYSSPSPPSDASGSPGSDGSLQDTAYESGYRRMPTPELWLDYLGAEPVRGDRILAMEVDQFIMGDHIYDLETEHWLKDHVVRPQERFFHEHMTRRDGFIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSR4</accession>
    <name>M5FSR4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625881.1">
        <property type="nucleotide sequence ID" value="XM_040769037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSR4"/>
    <dbReference type="STRING" id="1858805.M5FSR4"/>
    <dbReference type="GeneID" id="63684099"/>
    <dbReference type="HOGENOM" id="CLU_1626989_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="17166" checksum="183C21AC942FD29F" modified="2013-05-29" version="1">MSFAVPSVPRPPSHILLSSTITSIPKDNLSVQDVTQGMVQQSSPPAVPIKPVEELFSLDFHSPSGPAIVSTARKDSKSDILSLFGTSTTPAATAMWGAQTTSTIPQPFPLHRSVSTPTSNHTATFGADIWSGQSDPFASFGTTSSTPSGTKNDAFSDLWGDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT77</accession>
    <name>M5FT77_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795940">
        <property type="protein sequence ID" value="EJT96461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623359.1">
        <property type="nucleotide sequence ID" value="XM_040769493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT77"/>
    <dbReference type="GeneID" id="63684555"/>
    <dbReference type="HOGENOM" id="CLU_1970505_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="13523" checksum="6246A00A10B311F8" modified="2013-05-29" version="1">MAHRLSGIDAPTVGAHDACRFPPSALLRIHRALSSMCTSSAVYSCRPSQAFASSSSTSVADHSACSPLTNAAAHRTNGLRRSALSSTTFPRGLSHTPNLSLAFTTRLSASIPYLRRIRSISHILYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTC1</accession>
    <name>M5FTC1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_56177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626186.1">
        <property type="nucleotide sequence ID" value="XM_040775359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTC1"/>
    <dbReference type="STRING" id="1858805.M5FTC1"/>
    <dbReference type="GeneID" id="63690421"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OMA" id="FMRKFFC"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF19">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01812)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="42"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="508" mass="55954" checksum="365783C5CC7F061A" modified="2013-05-29" version="1">MAAVHGDDNQLLTSVGKGLHESALALSDAEVRRLRWKIDWAIVPYVSLLYLLSFLDRVNIGQAATAGLNTDLNLVGNEYAVALSVFFVSYVAVEVPSNLLLKRLQPHRWIFFIMVTWSIIMICMGLVHNAAGLQAVRFFLGLAEGGLFPGINYMLTTWYTREEQNMRISTFFAGATLAGAWGGLLAFGIRHMDGLGNKGGWAWIFILEGLLTFVCAVPAFWLVQDFPDDSKLLSPHDRARWLHRLSSSQGVTNAQLPFSWKQVKDAFTDWKTYVYALMYIGIAEPFYSLALFTPAVITGLGFSNANANLMTIPPYVVGFLTTLATAYWSDRVLVRGPFIVVWMTIVIIAYIILLCDVSVGVKYFALFLAVAGDSPCIASCITFIGNNVGPTYKRAAAMGFFFTIGNSGGLVASNVYPTPSSPRFIEGHSIALAFSAMAIVCALIISIHNYRTNKQRDEKWGVPAADGSECSPLRASDPVLLKKFGLEGLAPHQIMELGDNHPAFRYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTI7</accession>
    <name>M5FTI7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_25643</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623459.1">
        <property type="nucleotide sequence ID" value="XM_040774253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTI7"/>
    <dbReference type="STRING" id="1858805.M5FTI7"/>
    <dbReference type="GeneID" id="63689315"/>
    <dbReference type="HOGENOM" id="CLU_074848_0_1_1"/>
    <dbReference type="OMA" id="HYIGIIR"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000020">
        <property type="entry name" value="synaptobrevin homolog YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="139"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT96561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="199" mass="22377" checksum="EC9912B098F599DE" modified="2013-05-29" version="1">MRIYSLAIFTAPPGGSSTQLAAYADLSSYSFYQRGSVQEFLNFFSKTVVDRTPPGQRQSIEEQSYKFNVYNKGGADNLAALIITDLEYPPRPAFSLLQKVLDDFATEIPRSSFANPSSISFPTVKAYVDKYQDPRQADSIMKVQAELDETKIILHKTIESVLQRGEKLDNLVERSNNLSMQSKMFYKTAKKQNSCCVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTL3</accession>
    <name>M5FTL3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625637.1">
        <property type="nucleotide sequence ID" value="XM_040769093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTL3"/>
    <dbReference type="STRING" id="1858805.M5FTL3"/>
    <dbReference type="GeneID" id="63684155"/>
    <dbReference type="HOGENOM" id="CLU_468519_0_0_1"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067204" evidence="2">
        <location>
            <begin position="19"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="269"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="582" mass="59699" checksum="35A47B5A8195B603" modified="2013-05-29" version="1">MQINLLCSLLLLPALVSASSHLLVRSSSSSLIGRQAGAAACAASCTSASDLSALTAITNCASTDATCICDNSNDLSTACLDCILTAENLTPAQWTADCGSGGGVITGAGSASGSAPSASPSATSYCTTTCVSMADQASGCANSDLTCLCTNARMLSSTCLSCWLQLADLTQAQYQAECASGTGSNSAGGSGGNGNSLGAAPTTSSSGSGSAPTTGTSGGETSGAETVVVGGPPHTCVLSSTGTPLDSNISTPMVESQNVAALLRESPQKTPLAPAVPVDLWEPEAGEADFNFALPSFPFIVGVDVAGVVVKVGEGVTKFKVGDRVVTMTPLGKGIRFGVYQKYCCARVDATIPIPDSYTFDEASTTPLAYWTAALGLFISLQIPLPLSPSGKVSPTVKDETLLVWGGSSSVGALAIQLGVIAGFRVITTASPRNFEYVKSLGAKAVLDYHNTDIISQIKGLAPNLRYAFDAITEHGSIEAVLSSLSHPAAEVVIVLDFDGTLPPGVKTHKVFAGGIYYPGNESQITALIPLWDAVMSQGKIKPNPIKLMPDGLNSIEEGFDLMRQRKVSGQKLVYHPWETKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTL8</accession>
    <name>M5FTL8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_108330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627893.1">
        <property type="nucleotide sequence ID" value="XM_040768632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTL8"/>
    <dbReference type="STRING" id="1858805.M5FTL8"/>
    <dbReference type="GeneID" id="63683694"/>
    <dbReference type="HOGENOM" id="CLU_050309_3_0_1"/>
    <dbReference type="OMA" id="ARSKWQA"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="6">
        <location>
            <begin position="6"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="236" mass="25355" checksum="DB4A0A41C564CC9E" modified="2013-05-29" version="1">MSTCEPSEQFKQAAEYVATSPKLKKLPNETKLQLYGLYKAVTVSASPSGPRPGLLSFEGRAKWDAWDRIGKEFGGKPKEEVERKYLDVCKSSGWEEGVAPEPTGKREEGGEGGSSGPAGLGVSVSQMLREDEAEHEGKNDLQGAVVRGDVGKVNEFLLQGEAINGVDEYGFTALHLAADRGHKEIVQLLLDRGANVGIKDPDGETAISLAREAGHEEIVVLIQQVLSDHGQEGQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUM6</accession>
    <name>M5FUM6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparaginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_72718</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623859.1">
        <property type="nucleotide sequence ID" value="XM_040775977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUM6"/>
    <dbReference type="STRING" id="1858805.M5FUM6"/>
    <dbReference type="GeneID" id="63691039"/>
    <dbReference type="HOGENOM" id="CLU_004553_2_10_1"/>
    <dbReference type="OMA" id="DCCLYPR"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04323">
        <property type="entry name" value="AsnRS_cyto_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048952">
        <property type="entry name" value="AsnRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF16">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20917">
        <property type="entry name" value="AsnRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="270"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="84"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT96961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="578" mass="64962" checksum="8B3B85DB11A52664" modified="2013-05-29" version="1">MASIVDKVAEKVGDLSLTGDKGPEVYVDEEKGSDEKGAGTVAAPYATAVHAMTVKGHDINILTRKKDAQEYQPITKSALKNVKKTVETNERKSKKAAEEAEKNAKTAAEAKAREERRIEESKKIVLVEDSSLPKPTRSKIEGLQPLREQRVRVFGWVHRLRQQKEMTFIVLRDGTGFLQCILAGRCAQTYDALILTTESTVELVGTVQPVPEGKTAPGGHELIVDFWRTLGAAPGGDDAFNNRFNEQSDASVLADLRHLTIRGETAAAVLHVRAAVLNAFRTTFVKHSLTEVTPPCMVQTQVEGGSTLFEFDYYGQKAYLTQSSQLYLETCLPSLGDVFCIQESFRAEKSLTRRHLSEYTHLEAELCFITFDDLMTHIENIICETIDVLLSDPRMAELVQMLNPGFKPPKRPFLRMDYRDAIKYLNDHGIQRPDEVTGEIGDHVIGDDIAEAAERQMTDQLNVPIFLNKFPKEIKAFYMKPIPGDPKYTESVDLLMPGVGEIVGGSMRIADMQELLKAYKREGIDPEPYYWFTDQRKYGTCEHGGYGLGVERFLAWLTKRWTVRECSLYPRWMGRATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUP4</accession>
    <name>M5FUP4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUP4"/>
    <dbReference type="GeneID" id="63684033"/>
    <dbReference type="HOGENOM" id="CLU_1120155_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="28333" checksum="4F870832445CCDBC" modified="2013-05-29" version="1">MSKRTRSPGNEKDIPRARRPFRQPSPGTTEHTEHTRHQRIGTDEQVLREDHSQWFIGDGMLRARASNSWMDVQERSIPEHPPQPIMHPDVLREARQGDRNETVEPHPPCQNTKVHLHSTPAHAGCSRCGNLPHSPRQPSASIVLPGIETITSTLPPNPGHEQVIRVMIEVPVSRWRSWVENWTQHCAQHPSQPSGFVHVNDHNPAWRPVDGNHRWNEDRRLPPPFSSCRIPFPGQIASHQPLADRQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUW2</accession>
    <name>M5FUW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug efflux transporter AcrB transmembrane domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_109468</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626941.1">
        <property type="nucleotide sequence ID" value="XM_040768884.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FUW2"/>
    <dbReference type="GeneID" id="63683946"/>
    <dbReference type="HOGENOM" id="CLU_002359_0_1_1"/>
    <dbReference type="OMA" id="WWFDVES"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1640.10:FF:000029">
        <property type="entry name" value="Putative Patched sphingolipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003392">
        <property type="entry name" value="PTHD_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02460">
        <property type="entry name" value="Patched"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="680"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="792"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1138"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1161"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1190"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1241"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1271"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="585"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="714"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1333" mass="145176" checksum="7D331B13ED9017B7" modified="2013-05-29" version="1">MFSPELPCPDSGIATDPDEEFRQSLVSVCGPSFSTGGACCSSAQLDTLAENLKTVSPIISSCPACFNNFRDFFCSFTCSPYQGTFVQVTSTQTTTSGETAVKSVDFAVGEGFKQGFFDSCKYVQMGAANQFAMDFIGGGAKSADAFLKFMGDKKDVGPGSPFQIDYPRQWNESMTPLTRTPLDCASQDLGSRCACVDCPSVCPTLPYVPPPSDGSSCRVGMMSCFTFTLTLTYSLALAAFIALIIFRAFYQRRHIQLEGEEGVALSTGDAGSHQTLIGATSTQSGHHLTESASSVAGLSLHRAHLGRGTSLLDPLEATQPRQHKLNAWLRRFYFKLGYWCASKPWLTFAIAAAVIGVLNIGWARFGFETDPVKLWVAPGSESAAQKEYFDQYFEPFYRTEQLFFTSINEEPDGVLTLQRLKYIDDVQGTISSLRSESGIRLEDICLAPAGQGTPCVIQSPLAWLGDLDNEEESTWRETLNDCATTPSNCLSAWGQPLLPKYALGGIPQSDAGPVYSKASAVVMTFVVPDSMNATHKALVEEWERELRSFIEKSVVPTTAARHGMKVSFSTGVSLEEELNKSTNTDVPIVIMSYLVMFVYVSLTLGSSGRISFFAPSYSDAEIPEGFFPKAKYYLSRIRRPNLRMIVTSKVSLGLFGIIMVIIAVLSSVGFFSLLGVRATLIIAEVIPFLVLAVGVDNVFILVHELDKQNALHGPSTATSSANGVNGGNNGTPMSPSIRAPSLDDSVPTQLPAEDRVARALAKMGPSIFLSTVTEVVAFGLGALVPMPAVRNFALYAAGSVLLDGLLQMTVFVSAMTLDLRRVESSRIDCVPCFRLSQRVALMETAPNPEGSAVTRFVRKRYAPFLLKKEVKACVLAAFTGLTVLSLIGVRHVHMGLDQRLALPSDSYLIDWFNAIDNYYEVGPPIYFVAASADATVRRDQQHLCGRFTTCDEFSLANVLEAERQREASSFIAEPAASWIDDFFRWLNPQYTSCCRVRKNDPNTFCLPRDSERRCQPCFEDHTPAWNITLEGLPQGEEFMRYVKQWLISPTNDECPLGGQSAYGDALSFSADGKTLTASSFRTSHTPLKQQKDFINAFAAAHRIADNIASLTGTQVFPYSMFYVFFDQYAHLGSMTEETISLGLLAVLIITSLALGSVKTGVIVSCTVGLTVLNVGGVMGVWGISLNALSLVNLVIALGIAVEFNAHVARAFMGAVPGSQAEGQKERDERVWSALVEVGPSVLSGITFTKLIGISVLAMTRSKLLEVYYFRMWLTLIVSGALHGLVLLPVILSFAGGEGYALEDVDEDWMRSAVRRRGDEYAPFLADDDSVMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV36</accession>
    <name>M5FV36_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628528.1">
        <property type="nucleotide sequence ID" value="XM_040768601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV36"/>
    <dbReference type="GeneID" id="63683663"/>
    <dbReference type="HOGENOM" id="CLU_760817_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067296" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="40552" checksum="1B672CE03CA258BB" modified="2013-05-29" version="1">MRLPYDILALLPPLALARGDLCAWARVDAYMSRVATKLLYEQILLDASWISKVAARFPACVTRTSSGYLLLSQLTKAPLTPLLPLQTLSSHPELASHVRSFLIQLPALSGPGATFLLSLLSRTLELCTSLQTFAWECTVRCTDSVLRVLPQLRELREIQLSRPTCPLVYAPGLGRGREKGEWEYLSSWIEIGTAPPLSKLKHIYLHLPQPGTSSLWFTYLSSLSLPAPLESLYLDAPGVDAESVQGEEMERFAERQRGLRVLGLGGAGVGGRGVRGVLRECRALRGLVLRSVVEEGEEWDVLTLLEEAGPELRLAVVNEEHYTRSEGRVWQVGDPSWEELQRLKEEARWGRKDGWGGEERGSWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV73</accession>
    <name>M5FV73_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_25302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624089.1">
        <property type="nucleotide sequence ID" value="XM_040774110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV73"/>
    <dbReference type="STRING" id="1858805.M5FV73"/>
    <dbReference type="GeneID" id="63689172"/>
    <dbReference type="HOGENOM" id="CLU_047042_0_0_1"/>
    <dbReference type="OMA" id="LWCKFLQ"/>
    <dbReference type="OrthoDB" id="27198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DCUN1" evidence="3">
        <location>
            <begin position="60"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="30341" checksum="E56B8A8249C06792" modified="2013-05-29" version="1">MSRNSSVKIPRGQQEDLSQQFAVLTGSSPKEAMSFLKKYNWNINTAVDAWFTVPAHGSLPSAQKLGQVFDKYKDASDRIGIDGTIKLCEDLDVSPEDVVLLAIAHECKCPGVGEFTRDGWIGGLQSLGCESVDALKRLLPSLRQRLLSDPVYFKAVYFSTFGFAKPPDSRVLPLDSALAYQALLVPPALQLGQKGALASERPPGFGMREWAWWEEFLGKSSVKAMTKDVWNNFIDFVRQIDSEFKMHDLEAAWPSVIDEFVEFAKGKVAAMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVW3</accession>
    <name>M5FVW3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_54105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627396.1">
        <property type="nucleotide sequence ID" value="XM_040775230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVW3"/>
    <dbReference type="STRING" id="1858805.M5FVW3"/>
    <dbReference type="GeneID" id="63690292"/>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OMA" id="FQCTSYV"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="482" mass="55009" checksum="E27EFA3F12E85D7D" modified="2013-05-29" version="1">MGRWYWFTGIFDWYPKHMSRAEKRLVRKLDIVILAFCCVQFFLKYLDSTNITNAYNSGMSDDLKLFGNELNYFNVTYNCGYMLAQIPMLLALSRPGWARWIFPGAELIWGAITFTQSRAQNAQQLYAIRFLLGIVEVPSFSGTNYILGSWYTSEEIYKRAGTWYISSALGSMFSGYLQTAAYNGLNGVGGMAGWRWLFIVDGIITLPLAFIGFFTFPGLPSSKKPWFFSDEEHDLALQRMARQKNKVPGKITGSTLRRVFTSWRFYISISMNMIYNLTSYPTNYMSLYLKKATDSQGHLKYTIQQVNTIPTGVSAVSAFSSWLTASLVNVVPITTLFIVINVSGLFCNIILRIWNVPEGLKFLAYFGLGINGANNALMFGLANQICRRDNELRAVAMAGMLMGGWMLNAWVPVLEWPTVDAPRWQIGYTIQIPMICWLLSDCLLAVYLHRRQEQWYAKHGEEETTDEMVAESDEADYDEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX83</accession>
    <name>M5FX83_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627262.1">
        <property type="nucleotide sequence ID" value="XM_040768809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX83"/>
    <dbReference type="GeneID" id="63683871"/>
    <dbReference type="HOGENOM" id="CLU_576201_0_0_1"/>
    <dbReference type="OrthoDB" id="3265433at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="474" mass="53987" checksum="05E6BD1B946AFA05" modified="2013-05-29" version="1">MTPAVSEYNGRICAFPEEEPLHLPSSYEDPAVRRQLGLEHLSATEPELRKGQALDLLQKLREAVRRRRVMQAMKRTNVRHQGPQTMAARTLIRQKDEIDLLTNRYRRCYKSMLILGLPKDHKQYRNLEESDVYGVALTQLQEDLGTGRQRLPWYFHLGAEFAAADQKSSSSNEESLDEAVSRVTWWRTKAKADRWAEEEELTREEMRRTLKSYTFWRDIWCQKAASVGQSTQIERGRAAYAYKQSSVFARLYDEGISLCATGHERARSNVLTLARDLTTVKSLAQTQQVSQNAASLRPHSPFIQPHNRKLRSSQTRFPCLLTKDNVSISATYSSSTSDLGGGTDAVNKYEDVAYEAYMQDRQAYIDHFFPPNYASHSSSNALSAAIPFSTMAPTTAIPNVEFQPSPIVINNNCTTNIIHSNNTTYRNNNNSHHNNRSRNVHEEANTINEATDFVALFKKFFSAVTCGYLFPLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXC0</accession>
    <name>M5FXC0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_78480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629525.1">
        <property type="nucleotide sequence ID" value="XM_040776346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXC0"/>
    <dbReference type="STRING" id="1858805.M5FXC0"/>
    <dbReference type="GeneID" id="63691408"/>
    <dbReference type="HOGENOM" id="CLU_016922_4_0_1"/>
    <dbReference type="OMA" id="REGLNQH"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="51991" checksum="797B02704967680A" modified="2013-05-29" version="1">MAPVATRTAEISTAAPGVESKKVAGINAAADPPSAYTKDTAILHRTPFQPPTAVSAEGLYFTLADGTRIIDAVGGAAVTCIGNGNPVVKQAIKDQVEKLSPVPNMGRSNEPAEELAKLLLEYAPGAFEQVAFVAGGSEAMEAVIKLARQYFWETKQPQRTKFISRQLSYHGNTLGALSLSGHPGRRKVFEGILNHDSFHHVSPAYAARFKTPGETDEEYVARLAKELEDKFQELGPDTVIGFVAETVVGATTGCVAAPKGYFPAMKAVCEKHGALFILDEVMSGMGRMGTTMHAWQTYGDNVAPDIQAIAKGLGGGYVSIGAVLMSPRVAKGIREGSGYFFHGHTYQAHPTTAAGSLAVQKVIRENDLLKKAAEAGEYLSSQLRATLRSPSSIVAPYIFDIRGGGAFWGIEFDLGEKQTPKPFGALVQAKTMQKGLIVIAMAGSLDGGKGDYVILAPPYNVTKEEMDEIVKRLNESLEELVREYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXD9</accession>
    <name>M5FXD9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Galactose oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625044.1">
        <property type="nucleotide sequence ID" value="XM_040770686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXD9"/>
    <dbReference type="STRING" id="1858805.M5FXD9"/>
    <dbReference type="GeneID" id="63685748"/>
    <dbReference type="HOGENOM" id="CLU_008722_1_2_1"/>
    <dbReference type="OMA" id="PSPRVGC"/>
    <dbReference type="OrthoDB" id="4447at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="566"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="656" mass="74625" checksum="320267B56FBF3692" modified="2013-05-29" version="1">MAKKKGNAAAKAAKKAKIEKKSAKKEDKATKKGSQDDQDDQDLETILEEMRKEWEEKHRVTEETVEGPPSRRANATFTPDPNGNYLWSIGGEYFSDDGKAYFYNDVYRYTPEKDEWRRYTSPTCPGPRSAHATVGMPQAGGKLFLFGGEFSSLNQTSFHHYRDFWQFDIPTGTWERIETKVRPTARSGHRMAVWKHLIVLFGGFYDPGVRTVYLNDIWLFDTQTYKWQEVEFRDVDRKPSPRSGFSFLPVPEGVILHGGYCKEYVKGKRAHGVALEDNWLLRMDADPKLLKWERRKKAGHPPSARSGCTMAWWANRGMGILFGGVFDNDTDEETLESTFYNDMYGYQTSGNGKWVSLMLRRPKKAGGRRKRVPEVTLKTPAEQEDAQEEGHDEVEEDGDAIDVDETPVSPKVVIPTPIAIPDVVTSPIDDDPYDPEDTLPPPRYNAMLAVLRNTLFIYGGIYESGAREYTLDDFYALQLDKMDRFYCLRPNTIVFGNEESNDDDSEDSSDVDSLELNEQADEDEDEAEGEETKDQLMETEPPDKDIREKATAFMGVSMDATRSPEEVISTPLPGETIAMFYDRSRTYWAQKALEITQNRGKQGRRDGFELAQEKYASYKPLLEEVERILAEAGLDEEEIKRSAAGPSASGVSRNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXZ8</accession>
    <name>M5FXZ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate esterase family 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_127577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629825.1">
        <property type="nucleotide sequence ID" value="XM_040770942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXZ8"/>
    <dbReference type="STRING" id="1858805.M5FXZ8"/>
    <dbReference type="GeneID" id="63686004"/>
    <dbReference type="HOGENOM" id="CLU_015101_4_0_1"/>
    <dbReference type="OMA" id="HGHQNYS"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34414" checksum="C1007FE73B6AC7A4" modified="2013-05-29" version="1">MGGGAAPPQANRPRFSWPNTNNLLIFGDSYSFVQGTRGHANYSFIGNASHVALTPEELLTDEIIPRNTSSDGSNWAEFLTGCYSGLPKNCPRKLWDFAFAGADITRALLAPHHPFTLQMVDSVGQWAKYAARVLDLGGEHTLVAWWIGINDTGDSAGFTNITDWRAYWEEEMQYYFRAVSLVHSHGLKNHFFINVPPEERSPAWVNGNPGAPTLKQHIELYNEVLAEAVKSWERETPGVNAFLFDAHGWWNELLNNYGQYGFENITGHCQCTDDTYFWYNTGHPDEKVHKLLAGEMDRQLLGWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY18</accession>
    <name>M5FY18_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629850.1">
        <property type="nucleotide sequence ID" value="XM_040769967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY18"/>
    <dbReference type="STRING" id="1858805.M5FY18"/>
    <dbReference type="GeneID" id="63685029"/>
    <dbReference type="HOGENOM" id="CLU_030360_0_0_1"/>
    <dbReference type="OrthoDB" id="3352039at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="70022" checksum="3D693A6A142EB331" modified="2013-05-29" version="1">MSSSELSLPLSLSPIGEQRNKAGAVMRGIQQPEERSALLSQAIDLCTRLRDVLERLGPSRFTQSDYPEVSKVHELESTLHDRLRQVDEKRNDALAPVSRLPDDILRFIIQHGHDDQLLEHRLFVLGTGFARLVSGISRRWRAITLDMANVWTYVRFSNPKYLADEDFKPFHPWYGSAKALSPIYASNLERSKYSLLNVDMSIPPLDGARTMVKEYLHVCSNRVAELFLSANTSSMEGLQAVVSCVTETRNTLRRLRLCLVQSMTDMGGRETMEALLRCDLPRLIDVELHSVPLPLAHCPEYLALLRCRRIHLTLNRGSQYTPAHLLALLQCTPKLQYLHLMLYPLPVLDAPDSEAPLPRVLLPELRSIKYISISTSRKTFGRLVAPKLEKLSIDVLSRFHIPEQQEAYVADLLEFLSASSGLDGTPPPVKTLTIKGGILSSLERILLHTPSLEVLQTIFDRQWSVVEEEEYVGFLNKLGAQSLLATGHAEITSVEDVTHPPLCPNLQILESLAWATPNHIQSLTSLAAHRRSCGTPLTQIRMADWPAQWMPHVSAGMTGMPATPLEQYTLERVLAKEVEVLECGKFRWEWKEEGRWRKNQKVGEGDWGLRAMDAEGWHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY62</accession>
    <name>M5FY62_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795927">
        <property type="protein sequence ID" value="EJT96477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623375.1">
        <property type="nucleotide sequence ID" value="XM_040771441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY62"/>
    <dbReference type="STRING" id="1858805.M5FY62"/>
    <dbReference type="GeneID" id="63686503"/>
    <dbReference type="HOGENOM" id="CLU_658170_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47522" checksum="E8CF0B783E21EDEB" modified="2013-05-29" version="1" fragment="single">TILKVVQQIADHVAENGDLHSMMLTSRMCFDTAAPLIWRRLAYEEVDALLKILFVDWENNGTRIVPLSLERFTLYAAFARSIEISDIFAYWYEDQSRIKFDFPGHLRTAFDHLSSNTEHWFPNLQFLSLFWAECLETLLVTTQFIVPSLRKIELHTVRPKNFEGSQTWPLAVDGLLRRIGGTVHHLGSLSFWESTDDRCGERALAILIPTNPLTQLSISPAMLSRSVVKTAIGSSDLKSLELFSFRPARVEPPLSSFLSVNTLQSLVITAVPSIVLKLLRFLVADLHHITISMKTLHVHPIESAHYQQLGRLVADRFPHVEELILIFSQLYRDEPLLLDYLEPLNRCSSLALFSLYHGGILDVPDGKLDAMATGWPLLREFSLTCLHDKISSFIFGKEAGMSPILKDRPFSSRFYGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYJ3</accession>
    <name>M5FYJ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="19">ETF-QO</shortName>
            <ecNumber evidence="19">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_95134</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 19">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="19">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ETF-QO/FixC family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="19"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628486.1">
        <property type="nucleotide sequence ID" value="XM_040777275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYJ3"/>
    <dbReference type="STRING" id="1858805.M5FYJ3"/>
    <dbReference type="GeneID" id="63692337"/>
    <dbReference type="HOGENOM" id="CLU_009667_4_1_1"/>
    <dbReference type="OMA" id="INFQNCV"/>
    <dbReference type="OrthoDB" id="437331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000015">
        <property type="entry name" value="Electron transfer flavoprotein-ubiquinone oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049398">
        <property type="entry name" value="ETF-QO/FixC_UQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007859">
        <property type="entry name" value="ETF-QO/FixX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617:SF107">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21162">
        <property type="entry name" value="ETFQO_UQ-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05187">
        <property type="entry name" value="Fer4_ETF_QO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 19" id="KW-0408">Iron</keyword>
    <keyword evidence="14 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 19" id="KW-0813">Transport</keyword>
    <keyword evidence="15 19" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="566"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00052682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU01589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="606" mass="66796" checksum="B88C625B71117C3F" modified="2013-05-29" version="1">MHILRPLHRLSRLANTAHRALHLTPPLQREPFDPLTVDRASDDVDVCIVGAGPAGLSAAIRLKQLEKERRREVRVVVLEKGSEVGAHILSGAVVEPRALNELLPSWHTMDGHPLTQPATSSTMRFLTSSGSYPMPHPPQMDNTGNYVLSLSQFARWLGQVAEDEGVEIYPGFAGAQTVYSEDGKRVQGVITNEVGLDRQGRMKDSFEPGMEFRAKVTLVAEGAHGSLSKQLQNRFKLRQGRDPQTYGLGVKEVWRVRPEAYVPGKTVHTMGWPLSRDVYGGGWLYHMADGMVSLGLVIGLDYANPYISPYREFQRMKHHPFFKSVLEGGECLAYGARTLNEGGLQSIPQLHFPGGALIGCSAGFLNVPKIKGTHNAMKSGMLAAEAAYDALEHAGEGEVVDMSSYEERMRGSWVWDELTEVRNLRPSFAKWGFWGGLVYSGVDSLILKGRTPWTLRTPVGDAEHTRKASEFKPIDYPPPQPPLSFDILTSVSLTGTNHAEDQPVHLKVNPGIEARKKHVRENVQEYAGLLGRACPAQVYEYVDQEQGEGTLPGAEENVEDAGWDGKKLVINSQNCIHCKLCDIKVPTQDINWTVPEGGGGPKYSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYK1</accession>
    <name>M5FYK1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627847.1">
        <property type="nucleotide sequence ID" value="XM_040768624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYK1"/>
    <dbReference type="GeneID" id="63683686"/>
    <dbReference type="HOGENOM" id="CLU_075600_0_0_1"/>
    <dbReference type="OrthoDB" id="782330at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="296" mass="33387" checksum="779AAEC27E9BCF05" modified="2013-05-29" version="1">MPSMPVKKPLKPLPKPPTIAQLLSNAIKIVDIMVSTINKPNFSVAKYADGVLIWDAVMLLVRSRERHRVANLPEVWLDLLLEDNQEELVQLTRPAEEKKEEQEQEQEQDDADEFFWQSARQFLSMSVQWMCFFHVTDFFCQKHHSTTASSPAVANKEQSVKAKPSPTKGKVVATAPTHARHGRLSKAATQCVGWLSEETLATLLLVSKNNVVVESFLEENCAKKHKREDDKDAPGPLQKWSHLPEAEVKPLVALLSTVEHKMLELQKSLQMVQKALDTITSWAEQVQTLLGRALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYK7</accession>
    <name>M5FYK7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_50404</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630020.1">
        <property type="nucleotide sequence ID" value="XM_040774986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYK7"/>
    <dbReference type="STRING" id="1858805.M5FYK7"/>
    <dbReference type="GeneID" id="63690048"/>
    <dbReference type="HOGENOM" id="CLU_034105_1_0_1"/>
    <dbReference type="OMA" id="QICTDSW"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="10">
        <location>
            <begin position="279"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="49385" checksum="427B27A3E20DE682" modified="2013-05-29" version="1">MDQIPLIASYYPLLPPEERIPVTAFTFPLILLAPAPVFLLAYLSLRPNTLFVRLAILPFAVAPALYVLVGFRWMSWDLAPWNFALGLLCLLSVAKAVEFGTDTTGFPRLHKLVPNGISSTDKATPNGVASTEKDTVSRPAKLGPPQGLVAGLIDALDLSCSWRGIGWEHGKDTYVPPFPSPNLTGEELKRTWLKHAFKQFLLALFLLDALEVGVKQHPNFRHAGSASIWLPSLPPVQRWAVAVLMSYMTGSAVITGFQLCYHLLGLFAVLLLGHDPRSWPPIFEQPWRSTSLHDYWAKRWHQMFRRMFMIMGGYPVSWALRGLFGPMAGHVGLVVGTFVISGTYHTLSLFPTGIPLGWGSMIYFSMQGIGLGSERLFRHVTGRRVSGFGGWLWVMLWVVVAGMMGVDDWHMHGLGAGIIIPPVLSPLRAVIFPLGRMIQRHYWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYS2</accession>
    <name>M5FYS2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_17875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625589.1">
        <property type="nucleotide sequence ID" value="XM_040771314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYS2"/>
    <dbReference type="GeneID" id="63686376"/>
    <dbReference type="HOGENOM" id="CLU_888584_0_0_1"/>
    <dbReference type="OrthoDB" id="10641040at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="313" mass="34260" checksum="78C88AA6227995B3" modified="2013-05-29" version="1">MSSNQTTNLLTKLCFSTTILVIIFRTRKKLTAICGRTGHRWQEHLKGIIKGWHQWAQQALDLEAGSSSRPVLEDSESNSEYEDVEDDREEEEEERVGIRLGVMHMHQVDPRVASNAGATIIGGTVMTPVVSNESSRPDAYHAGTSVTNNLVAGLQATITLATERTIVNETSINGEMAAVCASQTAHLTDETEMNEEEHANAGGGAFLSIGDTLGIWFMQDTSIFLWFFTGAFDQTKKMLKKRVFFHVCRGLVAIVLFSLICWAMYSGGKYFFEHFNIQIGGGQLSISWVGNPGVNSTTTTGNVTPAVNGTMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ48</accession>
    <name>M5FZ48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_107520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628681.1">
        <property type="nucleotide sequence ID" value="XM_040768490.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FZ48"/>
    <dbReference type="GeneID" id="63683552"/>
    <dbReference type="HOGENOM" id="CLU_001744_1_0_1"/>
    <dbReference type="OMA" id="VYWWVIL"/>
    <dbReference type="OrthoDB" id="10031156at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1442"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1409"/>
            <end position="1422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1710" mass="192404" checksum="860BF59EA2090969" modified="2013-05-29" version="1">MAGRESLWENGRDEQVEVNQRALIDKVLARYSGEFTVFRELLQNADDAQATRAEIRFDTKAYMENSSLEVLADRLPNLKKDVVYQWTFKNDGMVFKEEDWNRLKKIAEGNPDEEKIGAFGVGFYSLFSVTDQPFVKSGSSWMGFYWRDGGDQLFVRRGELPNPEPPAASDGNPWTSFEMSLREPGPLPAPPIEIARFLATSLTFMNRLRDVSVYWNEKRLVRIVKELDTPRNLGVPGQLSGASPGKMMTIRGIDQTAFRMKASILRWVYTTGVAKPIISIPTPSQSNERGFFSAFFSRKQHTPTPPPVPTPAIQSEPDPFTEIESNVALNVYSAHVDVKMDRKLLQELERATKKKPSSKTVYHLIYTSKEDYDASAKEDLREFQATGSVFRSLRADMEHTGLAKVFIGQPTAQTTGVAGHMAARFIPTVERESVDLVDRHVSQWNKELLFVGGYLCRAVWEFKMSDIGRLWNENTDSTYRADLVQKCLHVMKFFSVYRAAPSSIFSDYIEAAFFACARNRTIPLLSTAGVLTRDKIRLPRHEFSGFLQQLPVIPEAIMDGVPNLMDTLTERGLVRDINFEDVLTELRSRPLSETEMINCLKWRINLNTDGVSHSADLKRQFLGAAVVTLPGATQGQGTVISLSEINNYLNPRGQFNIPTDVPLPRETLPYSISKFLTIDRLTHLFGWTELKLTDWVRFISSPDREVETNISLSPAFAERVLTIAVRGWQTMPDNIRTSITESLQQTSCIHTTKGMQKPTEAYFPTAHIFEDLPVIEFSKNAPTSRSNLEKLLLALGVRKHVDLQLVFSKMVTTGDWDIARLVEYLVAVKDMLSVEEKTRLRQTAAFPQEGQGALSKTRHLAQDLYVPDEALRQLKLPILDWKPKWKPHSEEAKFLTNVLGLKRHPPIETILELAAGEQPRAQAAFDYYLQHFDDVYAKKANGKVMESWAFVPAIHPDGSKHRSKPTEVFSKSEASIFGFSILDPAYQGSVHKLKISEQPPMEMVVARLIRNPPKSAPGAVAMFEYMSNRLAELGSGDLARLSDSAVVPYIEQKGSDMKLTMLKPTDCYFASSSQASGQFSELFHFVDFGTRANAFLRQCGVKSEPTVQEIAKFLVTNPRRFYQSSGGAERYLGILRNMAANRHLLPVRTRNELKKSAFLLCTRRQSSTSPKKSKFEDEDEDVVFSYELRKAEEIVIVDDASSYATFSVHLYGAPQEDTLEAFYEQLGSQRLSQLVSESYKPQGAADRSQFAQKTRALILERLPLFLHEHLASESRLKLVIKPEWLENDANFRVLSVRGLRLTRQLQWNNMRYDHTTEASAGGNRQGRSGPVTMWVSTSDSLDWFEVANVLCNILFQAHGVNDSLLLSTLLSTELRALKRRGYAVNRILQQQKAREDAIQAQEREHRLQAESSGLEPQQDSKQIESVANGSFLNSFNKLKDRLQGRDVSQGPSKPPSITAGPSGGSLESARPPPPPYPGQQTEFLDDEGAMPGSMPAPVMPPRLGQVSGGRVPRPEQHVTPISNIEANLNQALAACRPERGNLLHNRQEMSEVREALDEGYCDASGAVGDMIYVGNVESHRFYTKGVNDPKAIFSSKQQSLQRFSSAVIFLMGEIYGVPQTSLHIFFDLDGPLIAFNRNGSIFLNLRYYEAWHDADVQRGELGKALISWYFTLAHEIAHNLVQPHNSEHEFYFSSLCEAKLPALAGLIARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ96</accession>
    <name>M5FZ96_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transport protein particle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625794.1">
        <property type="nucleotide sequence ID" value="XM_040770543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ96"/>
    <dbReference type="STRING" id="1858805.M5FZ96"/>
    <dbReference type="GeneID" id="63685605"/>
    <dbReference type="HOGENOM" id="CLU_076409_0_0_1"/>
    <dbReference type="OMA" id="WTEVFRK"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28098" checksum="1CFD169F599066DB" modified="2013-05-29" version="1">MANRASLTPSLQAPTISSTNPSTASLLTPALLTLSSPPQAQVDINVVEYLLIEATRALADSARVAQSSKDAVEQAMRDAGWLPAPDAGKGETTAAAREAALGRLKDQVREEVERARRAKKEDDDEGAVRLRLENMGVQVGGNLAEKLCRDRQRFTDPLDSVKFLCKEIWPAVWDKQVDNLRTNHRGVYVLQDTSFRPLARLSSPFGSQEAIKRAKLHLAFPCGIIKGALARLGLNGMVTAEVNTLPQCTFQIKIPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0J0</accession>
    <name>M5G0J0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_110063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626244.1">
        <property type="nucleotide sequence ID" value="XM_040768990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0J0"/>
    <dbReference type="STRING" id="1858805.M5G0J0"/>
    <dbReference type="GeneID" id="63684052"/>
    <dbReference type="HOGENOM" id="CLU_038194_2_0_1"/>
    <dbReference type="OMA" id="RWPVCVT"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="31"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="35384" checksum="913BC0FCDCD1BB9F" modified="2013-05-29" version="1">MAAPLSKAESSYLSTGLLLSERADGRSLLDYRPITLATGVVPSANGSARARVGDTDVLVAVKLDAVRLDDVVDGDDERQEGKAQFVCSVECSPSALPHLPTDTLPDLSSDLTTLLSYYLSLPSLLPLRQLLIVPRRRAWQLSVDALLLSYGGNVTDVLFAAVRAALWDLRVPKTRNFVYDTPDAADSALGPGLGGFRIERAGVLDHARGLRRPEAADFELEDGSDEGVPLEGRELLPVCITLNLLTPIFYLDALPAEEACTPCRVILFVRPSGALCGLHRVGDSEIMPAELKQVLHEAVKHGQELAKALNDRLRDPKIASLGSNLGAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Z5</accession>
    <name>M5G0Z5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="3">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_85030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="3"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624355.1">
        <property type="nucleotide sequence ID" value="XM_040776712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Z5"/>
    <dbReference type="STRING" id="1858805.M5G0Z5"/>
    <dbReference type="GeneID" id="63691774"/>
    <dbReference type="HOGENOM" id="CLU_035168_1_2_1"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="6">
        <location>
            <begin position="39"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="265" mass="29160" checksum="2A6C7F7F6B0E50C9" modified="2013-05-29" version="1">MPLPPVLYHIFPLPIPYLPTLALQNSIHHLQLNLRKSTQDNPDILLLLQHTPVYTAGRREVEVKELEAARLKSAGADWVKSDRGGLTTFHGPGQVVGYPLWDIGRIGMSARCYVNNVESSLRDYLQQTFSLRTLDPSPSPGLFTTPERKIASLGISVRHRLTAHGFSLNVLHEPVRWFDQVVACGLEGVGATSVQDELPSAGLGEGGMTGVAEGIATAFGGRFGRSMQRLDLDVLGGLEGGTKVRQELELLEREGRREWLREPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1D3</accession>
    <name>M5G1D3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-lactaldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626534.1">
        <property type="nucleotide sequence ID" value="XM_040773352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1D3"/>
    <dbReference type="STRING" id="1858805.M5G1D3"/>
    <dbReference type="GeneID" id="63688414"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="DPCDEKK"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="37052" checksum="BDFEFA4B7231A424" modified="2013-05-29" version="1">MVAVLPPSIVLVTGASGFIAAHLCKLLLEKGYKVRGTVRSEEKGQYLHSLLSSPNFTYLIVPDIEAAGAFDQAVQGVDAVQHTASPFHGRAVDPQELIGPAVQGTKGLLESVQKFNPAIKRIVITSSVASILVPCKPGTTFTEQDWNTYSPGCVAREGINAPNMEKYRASKVLAERAAWEFVQKENPGWDLVTVCPPMVFGPIIHQVNRVESINTSIAALHSAFTPSGAKTGAAAGSSAGSWVDVRDVAQVHLEALAQEKAGGQRYIASGGPFSWQMVYDSAQSVNVPDGGGLDLEALNKGTPGSDRETKYNVFSSEKAQRELGVSFRPLGECVRDTLVSLKGYGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1J3</accession>
    <name>M5G1J3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628977.1">
        <property type="nucleotide sequence ID" value="XM_040768381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1J3"/>
    <dbReference type="STRING" id="1858805.M5G1J3"/>
    <dbReference type="GeneID" id="63683443"/>
    <dbReference type="HOGENOM" id="CLU_1704180_0_0_1"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="17034" checksum="7A69E1E3E9530AB3" modified="2013-05-29" version="1">MTAEGSVTVYGKYGDIYVSLTGLVDNLWDKDELSTAESPLHQDDQEMDQDGQEDRYALAPEEGGGHMYGVDWADLDRPALVQHHHAHHPLNMAEVVIDKPACPIGPREAAWLREVLTNLPDSDGQDEMALVWQKMLETYEVASAQPVGHDIGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1S0</accession>
    <name>M5G1S0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_115926</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629062.1">
        <property type="nucleotide sequence ID" value="XM_040770099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1S0"/>
    <dbReference type="STRING" id="1858805.M5G1S0"/>
    <dbReference type="GeneID" id="63685161"/>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OMA" id="VWIGDCG"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="73"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="25314" checksum="A7BC9D817B532423" modified="2013-05-29" version="1">MATNVFLDIGIGNKAAYAATIRDYEDAQGWIARNGPKYSLPSSLEELDDVQREALSEIYPGEIPYEKPVSLIVGRIIIELDPSSGLQKTRDNFITLCKGDRGVCKNAPNKKLHYLGTPIHRIVKDFIAQGGDVTRGDGSGGESIYGGKFNDEKPGLKAKPGRGSIAMANAGKNSNTSQFFFVLATDPAQLKKIEGKYVVFGSVVAGQDVLQKLNDIGTKDGGTMSEVWIENCGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1T5</accession>
    <name>M5G1T5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624585.1">
        <property type="nucleotide sequence ID" value="XM_040770772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1T5"/>
    <dbReference type="GeneID" id="63685834"/>
    <dbReference type="HOGENOM" id="CLU_1175397_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="236" mass="26031" checksum="44EC51530A9C69D0" modified="2013-05-29" version="1">MYEGKDRHETVPVCSLPRVADSRCDPLNEQVSDQNKEDERATNVAALPPAVSLTTPSSSSQRWPEPPPLPGPLLTGPEYEFEEAVKRAKRNLPKQRREYLANHPHIQLAETSTAGSGPQPRMQTLPEPTNRVRDGTRFLLSAGTAGNSMDAVRLSSENPSAHPAMFELSDFRLPEEDEAQEHGRPSSSNSSATHERHLGSATYRALPSTDAESSSMAEISWISWARSVWATWIGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1T9</accession>
    <name>M5G1T9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629077.1">
        <property type="nucleotide sequence ID" value="XM_040772606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1T9"/>
    <dbReference type="STRING" id="1858805.M5G1T9"/>
    <dbReference type="GeneID" id="63687668"/>
    <dbReference type="HOGENOM" id="CLU_505279_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="539" mass="60640" checksum="EA033185E724DFF5" modified="2013-05-29" version="1">MLLRRGVLLRRYLASQSNGTTTPTKPVRRIKTPMFREPLPLNSELTLENVLDGKPWPLKPCDKTSGAEGLATRLPSKHEREIDMSRQLRTVFDATPIMQNYRESTQSVLSVAQKLIEEAGDSLSTVVPINRIPAPLIHHPSWIRGSSETATSAWVDAYLLSPVELIYSALTKTIPVSTPEAYYNGSEPDIVRLTERADGTLIPLHIIEVKKRSVLANIVTLMRKWFASPDNLIKFSHISQSLGANEFHWPLFHFVDTKQWGCSNAKTRELNQAHYALVQIWSTFWDRGLSEGAFVSDENFVICIQGEDANELFVGVLSDTALNQQRAFLCLELFQLYRARNGRCAYEWTHLDPSIRVAIEDNFSQYESVFGRAPPHDAPPTSGFNQGRECVAECPTPPEKDMHRLHSVHEPSSTDPAVVIVDGHDGSDTPEYTPLYVDEIAVDMVGQEAVLDLKLMSKAGNGILGTVYHAELGDRKVMAKVVDIENLSSLEHELDVYLAIRSLWNETVPEVYGLHEALPKLHWYFLMLEKRSKIYVTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G263</accession>
    <name>M5G263_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629673.1">
        <property type="nucleotide sequence ID" value="XM_040772531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G263"/>
    <dbReference type="GeneID" id="63687593"/>
    <dbReference type="HOGENOM" id="CLU_2621979_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="8609" checksum="8B2E21AB454835FF" modified="2013-05-29" version="1">MKRAIDSPHRLFAADIVQLRSEDTVQHSPELQRLKCRMSLSPLSPLPQAHTPGSRACPQTVYALGEANPFPVPRHPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G274</accession>
    <name>M5G274_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNI-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_117594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626874.1">
        <property type="nucleotide sequence ID" value="XM_040770415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G274"/>
    <dbReference type="STRING" id="1858805.M5G274"/>
    <dbReference type="GeneID" id="63685477"/>
    <dbReference type="HOGENOM" id="CLU_028747_3_1_1"/>
    <dbReference type="OMA" id="WGHENAL"/>
    <dbReference type="OrthoDB" id="184583at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00116">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="436"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="436"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="523"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="640" mass="67141" checksum="DB3A1FB1E529D7E6" modified="2013-05-29" version="1">MADKIFTLAGQGLKLDSRADVEPHVEKLRAMEDVEEIHLGGNTFGVEACQALAEVLETKKTLKVADLADIFTSRLITEIPTSLSALCDALISHPQLHEINLSDNAFGGRSAEPMVRLLSQNTAISVLKLNNNGLGPAGGEIVARALLASAEKSAAASETSNLKVVVCGRNRLEDSAKVFAEAFAKHGTLREVTMQNDGIRMSAMLALVEGLSHCPDLELLDLADNTLTEVTDSGAIDLAGPRLVAKVLPRWKNLQVLNLSDCVLKPRGGVLIAQSLAGGSNPGLRELKFENSEIDPKTFGLLAEAISRLPEFTLLELNANRGDAEHETLQAIREALKKQGKEDALGELDEMEEIDEEEEEEEYVEVFPEAEEAEKEEGEEVVVVQKEQKEEEEVQKVTEELAEVKLDGAVPPAAAAPVEVFAAVVNVPATVETPAPVEAPTPAAAESSAPAPVEVPAPAAAEPQTTQETEASAEPSANGVPAPAPVEVPAPAAAVEAATAPTASETQQSQEASTHAPEPSVPAPEAAVKATAVQVPVETAAAAVPPKTTAPPSSFKPIEAPAASAPPSSFKPVDVAIPPATENGTATTSNAQEPETPAKGGSWRQKGVRRRKSILGGLGDLGDKIVGVFSPKRRVSNVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2D2</accession>
    <name>M5G2D2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631260.1">
        <property type="nucleotide sequence ID" value="XM_040772144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2D2"/>
    <dbReference type="STRING" id="1858805.M5G2D2"/>
    <dbReference type="GeneID" id="63687206"/>
    <dbReference type="HOGENOM" id="CLU_044876_6_1_1"/>
    <dbReference type="OMA" id="MAKFFPN"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="26462" checksum="A71D8C08C35F971D" modified="2013-05-29" version="1">MDYDDPSSLNAALQRKDVVISTLGRPAFHHQELLGQAAKAAGVKLFVPSEFGNPTEGREDSWFAQKNAARQKLKDMGMPYLLVYNGPFSDFVFNPHMGWDLPGGKVQISGKGDTPISFTYRRDIGRFLAHILTELPPEELAWKTLRIESDRTTMNKIAAEYERRSGKKLEVTHRSLEEMREAVRNSPLDVSETLRLDWELGGGTAGTPEQLDNKLWPEFNPTSAVDVLLKRDGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G5</accession>
    <name>M5G2G5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626949.1">
        <property type="nucleotide sequence ID" value="XM_040777322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G5"/>
    <dbReference type="STRING" id="1858805.M5G2G5"/>
    <dbReference type="GeneID" id="63692384"/>
    <dbReference type="HOGENOM" id="CLU_023194_4_2_1"/>
    <dbReference type="OMA" id="LICERQT"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF12">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="48242" checksum="B81E253852A64315" modified="2013-05-29" version="1">MSEPVSVVIIGGGQRGKAYGRYAIAYPHLCKIAAIAEPRPRTREFAIKQYQLPESGVFATWQDLHAASARSVAETGKPLADAICVCVQDQMHVEVVEAFAGHGYHILCEKPLATTAEECIRIAEVAKKAGCIFGVGHVMRYSPYNKAVIDVIRSGQLGKPVNIVHVEPVGYFHFAHSFVRGNWNNEKTSSFSLLTKSCHDLDILCHYLNPETPKRVSSFGSLTHFRKEAKPTAAGDATKCLECADEQNCAYSAKKIYVDPVSKGSVGWPAATITDGVPDIESITEAMKGPYGTCVYESGNNVCDHQVVNLEYSDGSTCSFTMVAFTEEICARQTRIHFTHGQLVGDMSSFTIHDFRTGNVSTVAPKPEDQSGHGGGDWGLMGNFVRAVKEKNQEILGTTVDEILKSHLTVFAAEKSRRDGVVIDVEQYEKEVREGMKLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3B5</accession>
    <name>M5G3B5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metallo-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_114050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631590.1">
        <property type="nucleotide sequence ID" value="XM_040769748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3B5"/>
    <dbReference type="STRING" id="1858805.M5G3B5"/>
    <dbReference type="GeneID" id="63684810"/>
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    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="38419" checksum="D3BC9811ACEC70E9" modified="2013-05-29" version="1">MGVDFHSVLGAPDNPGGLAWRALSSAQQEFIKALPKAEVHAHLNGCIPLACLQELARDHAFNGGSMTAEVQRGLAVLETGVVLSEISDFFGLFPAIYALTSTPPAVKKATQAVLASFLSTSPPQCQYIELRTTPRKTPHMTAEEYLSTVLDVIESFEGRAALILSVDRRMSVDDVSRYVELAKTLKREGRAIVGVDLCGDPLTGNMEDFAPILASVHDAGLKLTLHIAETPQNDEPDTLTLLSAKPDRLGHATFLTPAAQAIVRREKIPVEICLTSNVLCKTVPSLQDHHISDLLLHQHPVVICTDDTLPFRNSLFEEYALLLAPPPLGLGFAEVEVERIAREGMGTTFRSTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Q2</accession>
    <name>M5G3Q2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627379.1">
        <property type="nucleotide sequence ID" value="XM_040773213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Q2"/>
    <dbReference type="GeneID" id="63688275"/>
    <dbReference type="HOGENOM" id="CLU_2612457_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="9478" checksum="BAC897607109D6DF" modified="2013-05-29" version="1" fragment="single">MVLERVRSLEDILHQSKRFRRLSTENIMLNTCLPFKTFSRRAFCVEAADFHVLPIFIQSTYVIEEFRETLKIRRDNGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G460</accession>
    <name>M5G460_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629894.1">
        <property type="nucleotide sequence ID" value="XM_040772360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G460"/>
    <dbReference type="GeneID" id="63687422"/>
    <dbReference type="HOGENOM" id="CLU_3032295_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="55" mass="6123" checksum="7455710D5E271DDA" modified="2013-05-29" version="1">MEVNDVQKHYGKGTGMNPPFTDFQISGGWFDYAVCFTEKIPSGKQPRSMAPIISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5C5</accession>
    <name>M5G5C5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632350.1">
        <property type="nucleotide sequence ID" value="XM_040769656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5C5"/>
    <dbReference type="GeneID" id="63684718"/>
    <dbReference type="HOGENOM" id="CLU_043056_0_0_1"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF54">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="36843" checksum="DB77105B31CA5BCE" modified="2013-05-29" version="1">MEQQVDSIVAKLVYPWRPRWKTEGEVTSMRMLRARRTCVPEVYCYCAEPNPVGLEWILMQHMPGERADLRFADFDPKRRQHVIEQVADLVACLFSIEHRMIGSISQFSDNTSDEIVLGPLNDLAFEDPLFKGGAIPADQCGPFMTKRDLLEAFAFLGKPGLMPLENRGPGRKLIELYDFLDLHAGDQHTFHFSHGDLAGRNILVDNEGNVAALLDFGNAGFRPGELAVTLPDFIDNDADKTLYISALQRANESLYRYYIDGTEQRKMYEKGFRISCTPGNIIILLVRYWEAHECHCDQSSVVSLREQVFYKGLDEWLDSETKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5M4</accession>
    <name>M5G5M4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Phosphatidylinositol transfer protein SFH5</fullName>
            <shortName evidence="16">PITP SFH5</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_49556</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)</text>
            <dbReference type="Rhea" id="RHEA:38691"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:38692"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Endoplasmic reticulum membrane</location>
            <topology evidence="2 16">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Microsome membrane</location>
            <topology evidence="16">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the SFH5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630414.1">
        <property type="nucleotide sequence ID" value="XM_040774911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5M4"/>
    <dbReference type="STRING" id="1858805.M5G5M4"/>
    <dbReference type="GeneID" id="63689973"/>
    <dbReference type="HOGENOM" id="CLU_045138_0_1_1"/>
    <dbReference type="OMA" id="MVQIHDY"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042938">
        <property type="entry name" value="Sfh5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0492">Microsome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="17">
        <location>
            <begin position="96"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU03520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="31229" checksum="19AEC397D31E8DF8" modified="2013-05-29" version="1">MDEPQNSLTRKFTETEWTALKELRTLLPLIFEESFPKNENARRDPLTVWGVTLDPNRLDAKTSVVLMHFLRAQTMNVEAAKKMLLDTLRWRAEFDPAKAAEEPFDEAVFGKAGHMFGRDPDGRPIQYNIYGGDVDTTKVFADLDKFMRWRVGLMEKGCMEMDFENVDQMIQVHDYLGVGLSSRTPESKAAAAEATRIFRDYYPETLYKKFFVNVPAFMTWVFWLFRPMLSAQTLAKMEVLGISPITIGKGMLPYIKASELPKQYGGEADPNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5V6</accession>
    <name>M5G5V6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metaxin glutathione S-transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632535.1">
        <property type="nucleotide sequence ID" value="XM_040769680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5V6"/>
    <dbReference type="STRING" id="1858805.M5G5V6"/>
    <dbReference type="GeneID" id="63684742"/>
    <dbReference type="HOGENOM" id="CLU_077463_0_0_1"/>
    <dbReference type="OMA" id="RNAWLYT"/>
    <dbReference type="OrthoDB" id="198787at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF77">
        <property type="entry name" value="METAXIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="1">
        <location>
            <begin position="174"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="27268" checksum="4B39F8DB9AC935A8" modified="2013-05-29" version="1">MATTENPVLVSVHKFLARFPLYTYPAWPLSTTAPPSGLPTLWIHPSTKGQEPLSSDVECLKWQAWLALRGVAVSLRSDVHPDGGVDGKLPTLHLPDNTVHPAHAIPSALSIASLPHEGYASAEAELESKAFLALLESTLHKALFPDENPPRGPITGILPPEWLASVKPVSFVEAREAITALSGRLGSTDVWFLGSERPTALDAAAFAYLHTALTLKVGHPAEVIKREVERRPNLLRFHQNVEEEVRNAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5W4</accession>
    <name>M5G5W4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632545.1">
        <property type="nucleotide sequence ID" value="XM_040769683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5W4"/>
    <dbReference type="STRING" id="1858805.M5G5W4"/>
    <dbReference type="GeneID" id="63684745"/>
    <dbReference type="HOGENOM" id="CLU_477327_0_0_1"/>
    <dbReference type="OMA" id="HEVCISL"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="564" mass="62005" checksum="E88B32761327DC04" modified="2013-05-29" version="1">MSVTVEIVPTADCVAMVGDANTFTSYSLSGNVVINYEKSLVRSLLPVLQPLFYTVISIDIFFEGHQDVLDRSGGLASTAICRIQQSLIPPGSLPVVLSPIVHTLGIPFELAVPSWLPPTWMGRDGITAYSLFCKVKATPHYSASDLLLPHSPSTIELGNIYPLSGGRSLKRARSIWCLGRSGHTKSTLRTIEAKPVSIAVGRFRTPQSQIDMQEECCALFPHTYYILEPKLRITPDMLSDAAQVKLLNSLVLHIGVPSFVGVQETKVPVYCAIKSTISKELLKERKFEVTKVSFNIQQVESYQTPMDPEFEANHPLPPAEEHPPNMPLMAQNIFTSLNACGLLPKSSNDARWERHCELSKHDVTHTFDHPLSQGHCKINLNIPIVQEETGEDTVTIWPDMESPYCQVHHCIYMSIDCQYVDDLGQLHTENLAGTVPLRFTAVATSRSVSPVSPSFSVRNIDCFQPRVQKDGSPTRPLPPVPAYGQIFDENGETRMADPLPKYEPRRSNSTRSTSSSSSSGLSSSSGCGPETPLTRYGKTSIGSCCAPMSVHTPPRRHHAMAIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G658</accession>
    <name>M5G658_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine-rich PDZ-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-rich interactor of PDZ three</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_49135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRIPT family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630579.1">
        <property type="nucleotide sequence ID" value="XM_040774885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G658"/>
    <dbReference type="STRING" id="1858805.M5G658"/>
    <dbReference type="GeneID" id="63689947"/>
    <dbReference type="HOGENOM" id="CLU_133934_0_0_1"/>
    <dbReference type="OMA" id="MPCDKCE"/>
    <dbReference type="OrthoDB" id="147332at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019367">
        <property type="entry name" value="PDZ-binding_CRIPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805:SF1">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10235">
        <property type="entry name" value="Cript"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="105" mass="11204" checksum="3B2A7983B32B5845" modified="2013-05-29" version="1">MVCTKCEKKLSKLAAPDPFSASTSQGRKVGENKLLTSGVGPSSLKSKGSLANTRFTPYGGKCKDCKSTVTQNGAKYCHGCAFRKGLCSICGKKILDTKQYNMSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G698</accession>
    <name>M5G698_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bifunctional lycopene cyclase/phytoene synthase</fullName>
            <ecNumber evidence="8">2.5.1.32</ecNumber>
            <ecNumber evidence="7">5.5.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_23883</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>all-trans-lycopene = gamma-carotene</text>
            <dbReference type="Rhea" id="RHEA:32219"/>
            <dbReference type="ChEBI" id="CHEBI:15948"/>
            <dbReference type="ChEBI" id="CHEBI:27740"/>
            <dbReference type="EC" id="5.5.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>gamma-carotene = all-trans-beta-carotene</text>
            <dbReference type="Rhea" id="RHEA:32239"/>
            <dbReference type="ChEBI" id="CHEBI:17579"/>
            <dbReference type="ChEBI" id="CHEBI:27740"/>
            <dbReference type="EC" id="5.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carotenoid biosynthesis; beta-carotene biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carotenoid biosynthesis; phytoene biosynthesis; all-trans-phytoene from geranylgeranyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the lycopene beta-cyclase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="8"/>
    <dbReference type="EC" id="5.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626190.1">
        <property type="nucleotide sequence ID" value="XM_040773437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G698"/>
    <dbReference type="STRING" id="1858805.M5G698"/>
    <dbReference type="GeneID" id="63688499"/>
    <dbReference type="HOGENOM" id="CLU_012965_0_0_1"/>
    <dbReference type="OMA" id="WACPFLL"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="UniPathway" id="UPA00799">
        <property type="reaction ID" value="UER00773"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00802"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045436">
        <property type="term" value="F:lycopene beta cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017825">
        <property type="entry name" value="Lycopene_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03462">
        <property type="entry name" value="CarR_dom_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00018909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJT99292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="719" mass="78636" checksum="BE4E22F4ADABC85E" modified="2013-05-29" version="1">MSSYAEIHLRYTLPPCLVLFLLSYPFSNSRHHFALLFLLSVVILCTAPWDSYVIHRGIWAYPSNNVMATLFRIPVEEFAFFVIQTYMTTSLYSIITKPTFHPSLLPPRKRRGTLGSLLLLIPLLPCIPLSCTTSHWTYTALIVLWSAPFLSGLWYVSGPHLLRLPRKDVLIPILLPAAYLWLVDGHAIRSGIWTISERTKLGWELAPGLELEEGLFFLLSNTLLVLGNIALSQTFALADVLSLQHPHQNWHTDSNPLHTLPTLLAALLLPAQDYPSTLISHLSDAAVTLREKSKSFDLAAALFGDRCRLLLLSYYAFCRATDDFVDERQGQAQGQGGGEGEGGVEVIERFLGLCYPELRFELGKEEGEGGTAPAGEGEGEGEGAAKDYMNGKVHDKAANGHENGNTHKANRPTQDRMHSEKVEAYILTLPPQLQPSFSLFYLLVPFLPPEPVLDLVKGYEFDLAAFPVAGTKGEDVGGARGGEGAGEAEEERKKNENEQWNPAIKTEQDLIQYCQRVAGSVGVACTYLFAASQPQPQPPCTPPTQELLENATNMGIALQLVNIARDIEADARMGRSYVPSSWASSPSSPSSCQADPTTPATILSHPKECIALFRPRLLTLAFKYYALSAPSLHLLPTQSKQGARAAVAAYMSMGLLMRSCPGWPVRSGWTTAVKVLVVLGVLYLPLSLGGEGMSWELGARNWELAGQLGSLAAGSLGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6N4</accession>
    <name>M5G6N4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628379.1">
        <property type="nucleotide sequence ID" value="XM_040772881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6N4"/>
    <dbReference type="STRING" id="1858805.M5G6N4"/>
    <dbReference type="GeneID" id="63687943"/>
    <dbReference type="HOGENOM" id="CLU_804157_0_0_1"/>
    <dbReference type="OrthoDB" id="10453970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="36724" checksum="0B4DA8D5003D9DD9" modified="2013-05-29" version="1">MSYRASGPLHDSPSPGPGGERPERSRNAKAQAKHRAKRAAYVKGLEDDNLRLKAQLEAVMSQRGLSAMAGTSHGAIGSEPESRRLQEAELELARLRSENVSLRAQLERTGVSVPQHLDLYGGGIDRPHSASYPQRPAVDMHGAYPPPRSGSTSSNSESSISPAVQQPVPPMLPRSHQGGAVQPSQESMGPIPRVSSPAAVPGGLTTNNLSASSIRSPYSQPPLPPGQHNAQHATSNTRDSMTYQNYLSSGAYASTTSRGQSFMPQDGYMGQSSSYPGSYDQQTQAQPWATSYNVPGGSTTTTPNASTYQFQNAFAHPPPPQQQQQNTRQPPAGGGGGMVKWEAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G779</accession>
    <name>M5G779_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BAH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631478.1">
        <property type="nucleotide sequence ID" value="XM_040769734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G779"/>
    <dbReference type="GeneID" id="63684796"/>
    <dbReference type="HOGENOM" id="CLU_1255948_0_0_1"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="1">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="25681" checksum="8CEA4FD1E9DF87AC" modified="2013-05-29" version="1">MDSVEKIDWETRGTGEVTTYEVGEDVVVVPLSKAIGKRSRHDLTEVELWRGRILEIRIPKPKSGSSNEKKQPKYAWVVLAWYYSPLTYNTMGAPQDLKGYRKNDFGTYELIYAPTHTDPVHIETLNGKEEIYQYGEGDHDADEIPTDAFYTRSEFHTDVNKWVEGPPPRECVCKQTYKLYEDEVMYYCPRSACRTWYHQSCLDKGNYRMRVPDISKLEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G789</accession>
    <name>M5G789_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_23701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626525.1">
        <property type="nucleotide sequence ID" value="XM_040773350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G789"/>
    <dbReference type="STRING" id="1858805.M5G789"/>
    <dbReference type="GeneID" id="63688412"/>
    <dbReference type="HOGENOM" id="CLU_010591_6_0_1"/>
    <dbReference type="OMA" id="PQIDSAC"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067552" description="LysM domain-containing protein" evidence="4">
        <location>
            <begin position="17"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="23"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="171"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="224" mass="22364" checksum="65FB5296B36A2F14" modified="2013-05-29" version="1">MFFAAVLLASSALAATTTFSCSRNYTIVAGDTCDGISRAVGASTYQLAMLNPTIDDACSNLQIGQPLCLGLTDGSDCTTTYTVAGGDSCDAITNQFAINSTLLFLNNPQIDSACDNIYVGEVLCVGNQLFTLPAAFTQNGGLNAPSIGAPVPGGQLTSSIGPLSSAIPAGNVAGAPTSSPGVTANPAPTPSSSSSTSSTPTSSSAAPTPTDDGDDECEDDENDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7C9</accession>
    <name>M5G7C9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">VID27 cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_60719</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633025.1">
        <property type="nucleotide sequence ID" value="XM_040775645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7C9"/>
    <dbReference type="STRING" id="1858805.M5G7C9"/>
    <dbReference type="GeneID" id="63690707"/>
    <dbReference type="HOGENOM" id="CLU_007002_0_0_1"/>
    <dbReference type="OMA" id="RLNETKW"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="215"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="410"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="772" mass="87606" checksum="1596BDE5A8A0FBB8" modified="2013-05-29" version="1">MFMLRNLFGKVWSDPQASELAKIPNGALYLVRQDHIRSSRECIYLAAMASIRRTSTEFHYELAISRVFDRGEVLDEDEDDDSERSFLIDEQLEFRQATYEGQPSFVWKDVAGDMFEFVANGATKATVDFFEVNYLKAAFERKYQRSSENVSDVELEALRYVPGRINGPIPQSRAIREKSANEEIVTSFQRFKSQSVSSPPKLNPSKKVTVADNGEILSEEPAVLYLWSLQEGKFIPQATSTAQLAETENFVFWILAKESDRKSGTSIILAHPVTADINGRWSKVHLSFTWNVYTFPTPERMVTETWCFKFDEAGSYQRFQDRMNICLWETLNQMRWGKIKADEQAYAESSWQDEDVEMTDAEVEEELEQERAREEDEEDEEDVHEIMTAYDEDEDEDEERQALKSAKGVTNSHLAVGHVVDRSFVVRGNKIGVFRHTDDDKIKYASTINKIATPKGEVFTPKKVMLHDRDHTMLLMNDNNPNSLFQMDLERGKVVEEWKVDDDRKLVEIAPDSKFAGLTGQQTLVGTSHNALFRIDPRQSGNKIVDSETKQYVTKNEFSTVTTTQGGKVAVGSNKGELRLFDTIGKNAKTALPAIGDPIIGLDTTKDGRWIVATTRTYLMVVDTLIGAGRFSGQLGFDRSFPADAKPIPRRLQLRPEHVAYMGSEVSFTPARFNTGPDQEEKTIVTSSGPFVIAWDFKKVQQGRLDKYDIKQYADKVIEDQFKFGNDKNIVVALSNDVLSIDKKLLQRPTRASLSTPAKLLRSKSGIVNSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7N3</accession>
    <name>M5G7N3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NUDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_117443</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nudE family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626685.1">
        <property type="nucleotide sequence ID" value="XM_040770383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7N3"/>
    <dbReference type="STRING" id="1858805.M5G7N3"/>
    <dbReference type="GeneID" id="63685445"/>
    <dbReference type="HOGENOM" id="CLU_027730_0_0_1"/>
    <dbReference type="OMA" id="NGHIVHK"/>
    <dbReference type="OrthoDB" id="5877028at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
        <property type="term" value="P:centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="233"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="425"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="546"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="69176" checksum="4AE0E3F57EF5B6FF" modified="2013-05-29" version="1">MGGGDDDVPEFDPVSAHPADEWRNMYIDKHNLLEETMEELADFRLTSQEIEQEMEKELKEKEKAVTDLKVRTGKIEIERDDWKNKFMKLQATFNTTTNSLQRELDSLRKMTTEYKTQVRELEMGNDDLERNERYAKSSLTEMEEKFNRVTEEKIILEHELMSKAAQEEELQRLRDELRGTSQSSINAKLPSHSRQMQLETQSSLGPSPATSPSLQGEKEESLLHLDDLTVQQKRMSAMPQSPAVSSTASSPAPTPPPKPYPPLANAKMLRSSPMSNSPSRIPAPRKSMLAESTASAGTVLPRTRSAATQMMGEMRARVKLLENRLNARRAVSNAFSRKKEPVVPEVEGSPGWVVLSDTSSAADSSSSFVKIAPPPPAPTRPLSSASRSSTEYGRGSFDRRRSIDVKSPPTSYISRIPEDVERPRPSSQSSAPWRTSSRPASQLGDSTATIRASETQRFPLRPPTPSFIPKPNAEQADASFDPKASLGGIKATIGRSQSVRRAISTASGPSRTSSKASASRPVSISSVPAAPSIPKGLERSMGMMDISSIPSPSSISSSASRIGRPSSSAVGNVRRPASQQAATRSQTPLGYGSYGSYDRDDEQELGVGSVKEPLPGIGLGRAKAKARIPSGNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G821</accession>
    <name>M5G821_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631179.1">
        <property type="nucleotide sequence ID" value="XM_040769854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G821"/>
    <dbReference type="GeneID" id="63684916"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="GIGLEYC"/>
    <dbReference type="OrthoDB" id="7289984at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="233" mass="25277" checksum="3EC9A85F7DD6BB86" modified="2013-05-29" version="1">MSTTWLITGTSRGLGYEFVRQLVEDPANTVFATCRTPEKAEKLHALKPKGKLHILQLDQEDKTSVDKAAKEVEKLLEGKGLDYLLNSAAAQYGGNDSAVTLDSQQFMDTIKNCVLGPALVVQALVALVEKGNKKVIMNMTSGLASIGLDCGPKNASYSIAKTALNMYTYKLAKEKPDLITFVIDPGWVKTDMGGPGAMLEPDFSIGNMLKTIKGATQKDSGTFKRYNGEPIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G845</accession>
    <name>M5G845_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Winged helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_48321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631204.1">
        <property type="nucleotide sequence ID" value="XM_040774824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G845"/>
    <dbReference type="STRING" id="1858805.M5G845"/>
    <dbReference type="GeneID" id="63689886"/>
    <dbReference type="HOGENOM" id="CLU_1551272_0_0_1"/>
    <dbReference type="OMA" id="ICILEFA"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="18994" checksum="72B5E79150AC1013" modified="2013-05-29" version="1" fragment="single">LLSRPEYGRFLRWNEAGDAFILMNSAEFAQFVLPRFFRHSNVSSFVRQINLYGFQRVSTICILEFADINSGDPTQGTDAVQASGFTHPYFRRGRRDLLKNLKPRSARRSKKAAAAAGATGQNGQPGKKEGEGLPLPEQKGRGRGRASNMPPTPTNMSAPPLSNPINGMVSNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G849</accession>
    <name>M5G849_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_73826</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633285.1">
        <property type="nucleotide sequence ID" value="XM_040776028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G849"/>
    <dbReference type="STRING" id="1858805.M5G849"/>
    <dbReference type="GeneID" id="63691090"/>
    <dbReference type="HOGENOM" id="CLU_028692_1_1_1"/>
    <dbReference type="OMA" id="INWETSW"/>
    <dbReference type="OrthoDB" id="17164at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000262">
        <property type="term" value="C:mitochondrial chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU06391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="184" mass="20735" checksum="29A2073EE4976228" modified="2013-05-29" version="1">MGPLPEPGDGRPTDWSRSYHGLSSQPFPKDIAEILMAPLDPEDVEIKPDGLIYLPEIKYRRILNKAFGPGGWGLAPRGETNVSPKVVSREYALVCLGRLVGIARGEQEYFDPSGIATATEACKSNALMRCCKDLGIASELWDPRFIREFKAKHCSEVFATHVVTQRKKKLWRRKGDKLEYPYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U0</accession>
    <name>M5G8U0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633520.1">
        <property type="nucleotide sequence ID" value="XM_040767781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U0"/>
    <dbReference type="GeneID" id="63682843"/>
    <dbReference type="HOGENOM" id="CLU_605534_0_0_1"/>
    <dbReference type="OrthoDB" id="3343959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="452" mass="50853" checksum="7FAA036EF5BF4E31" modified="2013-05-29" version="1">MALLPELLIEIISHIATPANDLAYSLPPANRKALYVLCLTSAACRSIALPHLYRRIYIQMASQIPSLQQGTHIKKHTRTLAVGPLSFEPEIAQLVCGLLATLSSSLERLLISCWGGQTDAERSALAGCSGLQEFILPRESNFWGLYTASDQGLHMTLPRSWVGIRRLSLYRVHLEDFLLAQGHFPQLESLCLSDCWLPTSGQVSPAFTRFVRELSGSRQVFFMVYTEEAGLAKELIRALRAVIGDNEVVFGLRVVNLIEERFKGGIPEIRNTRDALIVFEAVRMGILPLIRRRLNVDEGKEFIQDGAVFVWEEYDFIQGVDGSGGSFQRWTDRMKWSQSKVEGPFLYYEEKVDLPPGAEKVHPSFHAKSRTRPVKPDGMTKQTFSATALFTDPSAPKTKKPRKWHLTTYFRRSTWPTLPTIESDPDLKDITIVDGMFETKGLRPGTHTAFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y7</accession>
    <name>M5G8Y7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_19722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633560.1">
        <property type="nucleotide sequence ID" value="XM_040771632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Y7"/>
    <dbReference type="STRING" id="1858805.M5G8Y7"/>
    <dbReference type="GeneID" id="63686694"/>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OMA" id="KGCQLAR"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11309">
        <property type="entry name" value="14-3-3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="7"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="29156" checksum="2E88B642ED5BAC13" modified="2013-05-29" version="1">MAETHVREDHVYLAKLAEQAERYEEMVDNMKKVASSDQELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKGNEAQVAMIKGYREKIESELAKICEDILDVLDKHLIPSAASGESKVFYHKMMGDYHRYLAEFATGEKRKESADKSLEAYKAASDVAINELPPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQESADKPEAKDDEAAPEEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G936</accession>
    <name>M5G936_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632143.1">
        <property type="nucleotide sequence ID" value="XM_040769628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G936"/>
    <dbReference type="STRING" id="1858805.M5G936"/>
    <dbReference type="GeneID" id="63684690"/>
    <dbReference type="HOGENOM" id="CLU_055335_0_0_1"/>
    <dbReference type="OMA" id="YLCHNCY"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRA" evidence="2">
        <location>
            <begin position="182"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="369" mass="40802" checksum="2482AB7A305424C1" modified="2013-05-29" version="1">MAPAAPATPSRVELRKFVLNYLCHYCFVDTAKAFSKCVPLQGWYEGEEGGIRPEDVVLTEDHAQQLKVRREIREDILSGKIPAARENITTHFPSVLSDDPPPPPPPTLPHIIPTPPPEIPQTRVIPSFPSSLSPQNISITLSIQQWIETLRTVPLPYPASPSPVSPGTSVTATPVLPSFEAQDQTALIVMGRQLYARARQLNPPHNEQFREELVGIASLIAYKEPEKAPEIVRHHLEWSRRKGVATQVNSAILSSLGYPPYVPLASLVRQLTFVYQMLHELGVHPPEGGQLGGIELLEASEDDQDWAAEAIPEFRLSAYLYKDKKGKGDVEAIYRTDDDEDMDADGEAEPAPEDGDKDGEEEGTMETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G964</accession>
    <name>M5G964_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA binding protein Ncp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631619.1">
        <property type="nucleotide sequence ID" value="XM_040767952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G964"/>
    <dbReference type="GeneID" id="63683014"/>
    <dbReference type="HOGENOM" id="CLU_831611_0_0_1"/>
    <dbReference type="OrthoDB" id="3267800at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36566" checksum="443854CE3B0AF1B2" modified="2013-05-29" version="1">MSIAFLANLADDDLVDKNTIRSSPTTYRTALTNQTEKRKSSSSAPVNTVDAFKDVKGASRVVESDSVRQAPVDAGKIDSSFDHDSAHPSFRNTKLNGHGIPIDKAESTRSSLAPTELPASFHTALEDSTIRPGHGVETESIRSESIRTGTPPHIPPSAVGTFATGAATSGPQALPDSDLRSRATIAESNVGSKILRRLTKREAKDGKRMSRILQNEAVTEQRTLDLAIKELERLQKVQRKAAAAEAEALSTHTKASRQENKLSQTYFSAKTRWEQATAYLESCTVALEKSREHARRQTELLREKTAEVDRLRAQKATDDRERQVKLAALSNPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9H9</accession>
    <name>M5G9H9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_81302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627355.1">
        <property type="nucleotide sequence ID" value="XM_040776504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9H9"/>
    <dbReference type="GeneID" id="63691566"/>
    <dbReference type="HOGENOM" id="CLU_023630_0_1_1"/>
    <dbReference type="OMA" id="HYAEHFG"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="504" mass="56398" checksum="C0F2A5E7772D3DAB" modified="2013-05-29" version="1">MARLRLDSTSVTSFNIPTQPQHPLFSLDEDTDKPFFPPHTFLQPLDHFSSQSPQWAQRYWLNARYYTPGGPVFLFDTGEGPGEDRFGVLDTGIVAILARETGGMAVVLEHRYYGQSMPVSNLSTDSLRFLNNAQAAADSANFMRSVHFPGVDEDVSALNRPWIYYGGSYGGARAAHMRVLYPELVWGAIASSAVTNAEINNYEYFEIIADYASPHCISALRASISLIDTHLSSPFLAPFMKSLFSLSPLSNSDFAAILSAPLGAWQGKNWDEREAHRPGEWEEFCKCLTRGVGNGMGKVAAWMATRNYAQYIKDTVVSECPEGMTVADCFGSDDPTKFQNTSITESWRSWAFQVCTEWGYFFAAPPYPSIVSQHLQIDANAKHCQAAFPNGEHYIIPAWPNVSIVNELGSYGIAAERLALIDGEWDPWRPRTPHSIHAPVRNDTISEPFMQIPAGVHHYDENGLADPRKEPLYIQKVHHEEIGFVKAWLAQWRVLHGRLVTEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9N5</accession>
    <name>M5G9N5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_92794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632413.1">
        <property type="nucleotide sequence ID" value="XM_040777106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9N5"/>
    <dbReference type="GeneID" id="63692168"/>
    <dbReference type="HOGENOM" id="CLU_1137969_0_0_1"/>
    <dbReference type="OMA" id="TPHISFP"/>
    <dbReference type="OrthoDB" id="14339at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="27628" checksum="5AEA5853C33553DF" modified="2013-05-29" version="1">MSSGTTVAKDWDNQSIFSESSEGRNVGGAISPTGGNIQPVGTASASADLLRDMVAKRMKTFTFLKTVHEGKGHWLQSIQFTRQELDREFDNAKMRKRTHRFHVLGLSLSSLWDISAPNDFLRALLAILDEFDHFQDDVNYKPKMRNLFRGVSSKQLRKGSAGDTPYADFFLDGATLLTPPFPFPLDYSQTLYTLYDILLETYHKMYRFLGPSILPSSHAPSLHLIDRDRIRHLPKMAFLLAEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V3</accession>
    <name>M5G9V3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="11 12">3.2.1.106</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_20026</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="11 12"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632488.1">
        <property type="nucleotide sequence ID" value="XM_040771767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V3"/>
    <dbReference type="STRING" id="1858805.M5G9V3"/>
    <dbReference type="GeneID" id="63686829"/>
    <dbReference type="HOGENOM" id="CLU_007380_1_0_1"/>
    <dbReference type="OMA" id="FNWYNTT"/>
    <dbReference type="OrthoDB" id="410058at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.110">
        <property type="entry name" value="Glycosyl hydrolase family 63, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031631">
        <property type="entry name" value="Glyco_hydro_63N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038518">
        <property type="entry name" value="Glyco_hydro_63N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF11">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16923">
        <property type="entry name" value="Glyco_hydro_63N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 12 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067657" description="Mannosyl-oligosaccharide glucosidase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 N-terminal" evidence="16">
        <location>
            <begin position="30"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="15">
        <location>
            <begin position="300"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU05594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="807" mass="92127" checksum="314D2BE0761E7460" modified="2013-05-29" version="1">MRILYLFFALLSIVFVKGSEKTSEENESQSLLWGTYRPNLYFGMRPRLPKSLMTGLMWYGVQHLTAFTSLRHSCEQGDNLRGYTWTEHDPRDGGVEVVRDELNNLDLRVEWLKTHEGKHGGSWSVRISGKPLDTSRPSLNSLIFYAGLEGFGGLEMDQRQLSQVPEGPLALTGRTPELGEFKMKFENGPESRYVTRGRRWEDFVAVSSRTHVAGMVVADGTIWQAEDLVSRALMAHAEPLVTKYGGKEAPDELPDAAFLLMLDDHIARGSNFYAIQKIFDGPFSFDVHYETADSKQTFDRKTFTTSLAAFKESFDTRFKDVFPIPKDATPGLFEFSKAITSNLLGGIGYFYGTSIVDRSVIHEWDEEDSVDTTKPSGGGPELAGPTQLLTATPSRSFFPRGFYWDEGFHLLHIGEWDNDLSLEILRDWMKLVDEDGWVGREQILGEEARSKVPKEFQTQYPTYANPPTLAMAVTAFIQRLKQIDDPADMETLGLGGAQLPLIQRPEAEHGNALLRDPEAARAYLHSIYPTLRRHYLWFRRTQKGQIKQWGRKASSRTEAYRWRGRTPDHVLTSGLDDYPRARPPHVGELHLDLISWMGFFSRTMKQIAGYIGQDEDEAEYAAIEEAIITNIDDLHWNKEEKMYCDASVNEEDDSYHVCHRGYISLFPLLLGLLPPDSPHLGSVLELMHDRQHLWSPYGIRSLSASHPLFGKDEDYWRGAIWMQMNYMALASLKNIYTQQPGPYQKLAHQIYSDLRHNIIKNTHKEFERTGYVWEQYDASTGEGRRSHPFTGWTSLVTLIISEKYPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAH8</accession>
    <name>M5GAH8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_74568</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632254.1">
        <property type="nucleotide sequence ID" value="XM_040776074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAH8"/>
    <dbReference type="STRING" id="1858805.M5GAH8"/>
    <dbReference type="GeneID" id="63691136"/>
    <dbReference type="HOGENOM" id="CLU_012583_1_0_1"/>
    <dbReference type="OMA" id="PSHKFQK"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="308"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="479"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="606" mass="69125" checksum="188CAC6791475A54" modified="2013-05-29" version="1">MSASRGDGGYYGRTPSRNAPPGSVRRSSQYSGRASAAALAQINQPKTEMRPIRDKQWIAMAAQTVMDHLIENRFPLPLERKMFDQGPTLKLFQAMFMFLTHDVLYPGYVFGKGGRKFEEDVITLMKDLRYPHADQISRTALQAAGSGHAWPATLAMLYWMVELSQAKLQWFNPEMCDDPNLTPIEKLSPEQSNMPERYFIDYLNQAYRAFLDGSDDFSDLDQQLRQSLGKVTMHPVFQELTFSGIEQSNGAVIQETERKAGQLKKTVAEIEQIMSHVRVIQSPRNERDQLEKEHELQLADSVKFQKMIEHNNQKKSKLEDALQVLNAAISEAEERLVALRTEHGGLLKAVEEQNLSPEEATRMTTERDTLARTLKDLHDRVAEASKTQWEREMAVAKRGSSMEDAIQEYMQVVYRAGLFPDAPKPFDQIQFGLDVNLTAPPAEMLNADIRHSIRPAVTRFGEERRLVRTRLDDERIVVEDELDRLTQFVENQKEELENREVRLNQLLERADEIREHAATETADSNLESARLEREVANIRTAAQQSALGLDSRLQALEIEYADLQHKTARLRDEVLKEVVNHTEAIVTFRTQVSASLDSLALYAENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAQ1</accession>
    <name>M5GAQ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627900.1">
        <property type="nucleotide sequence ID" value="XM_040772969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAQ1"/>
    <dbReference type="STRING" id="1858805.M5GAQ1"/>
    <dbReference type="GeneID" id="63688031"/>
    <dbReference type="HOGENOM" id="CLU_065200_6_2_1"/>
    <dbReference type="OMA" id="QFGKQWD"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="19860" checksum="4D8FF5F836B66D89" modified="2013-05-29" version="1">MMSLSTRVGLAFAYPNVESRICTYQPPMWMILAGIFGSLLGWVGTELRAWCYKALGQYFTFHLAVQENQTLITTGPYTYLRHPAYLGGCLQYLSMLLTLILCNPISMCWGRHLLKYGPQIEAGFMLFFFVAPWTAYFKRVDAEEKMLKAKFGKEYIEWEKRTWRLIPYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAR1</accession>
    <name>M5GAR1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">AAA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_112785</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632858.1">
        <property type="nucleotide sequence ID" value="XM_040769513.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GAR1"/>
    <dbReference type="GeneID" id="63684575"/>
    <dbReference type="HOGENOM" id="CLU_000536_5_2_1"/>
    <dbReference type="OMA" id="IVHNANV"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140674">
        <property type="term" value="F:ATP-dependent histone chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001218">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000016">
        <property type="entry name" value="ATPase family AAA domain-containing protein 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="344"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="645"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="814"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="887"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="946"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1076"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1119"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="888"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="961"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1076"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1127"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1337" mass="146998" checksum="AAC3461C2F9700F8" modified="2013-05-29" version="1">MHGRRTTRPATYAEEDESIDDEPVHRSHRRSHHGGVNGNRPSKRNSGDFIVEENEEQQDGDDDYGRRRSLRSSTRDQRHGNTPPQKKRRSALEQLLTKRGHTKPRSTRNSRRASGSDDFDPEGGTSGDSNESDILQGGSEEMEMEQEVEEEVEEEMEDTEPAEVEPKQYSFRERRNKPNYTLPALLTNEEIERQRKEAAAEKAAKKAKKAPKMNWSITGKDLSRLLGEPEPDSDDDVGNTPAKRGMFGTGAGAGLTGAGAGGVVGGSMFADGAAVGGGGLAGTPSNLGKIGGQDGTSDADPLGVDLSVSFEQVGGLDNHIQRLKDMVFLPLQYPEMFEHKNITPPKGVLFYGPPGTGKTLVARALAASCSTGTQKIAFFMRKGADCLSKWVGEAERQLRALFEEARACQPSIIFFDEIDGLAPVRSSRQDQIHASIVSTLLSLMDGMDSRGQVVVIGATNRPDAIDPALRRPGRFDREFYFPLPTLEARRKILEIHTNKWQPPLGPELTEQLAELTKGYGGADLRALCTEAAMNAIQRTYPQIYKSKERLQVKPDNVIIGARDFTTAMKLIVPSSERSTSSAAVSLPDQLKALLEDAVERTKACLDRALPPTKEKTTLEEAEWEEEEGGFASALKLKAMESLRVYRPRIIIHGPPGMGQNFIAAAALHYLEGYNVQSLDLGTLMSDSSRTPEAAVAQLFTEAKRHKPSILYIPGLTEWANAVTPTTRATLKSCLDGLSPSDPVLLLAIVEGPLRDIPPDVRSWFGVAIDNRIRLDKPTEQQRAAFFADLVKTIMTPPDKFGDAVPKKKRVLEELPIAPPLPPRQPTAAELAAQRANDQRTRDLLRWKLSTVLNDLKRKYRRFWKSVVDEYGLSPLYFEELSVPEPHPEPVIVPEPEPELQPQPEPQPPSSPVQPPSQDPLLLTDGSIQENGVPVEVETVPPQILVNGDAAHAPSSPPPAEALPAQPVTQPSTPPPPERPQRELRYLDVSGEVMHEKVFHNAYLTPADFLLDIDRVLYNAELADQYYGARDKDRLEKAREMTLTAKALMGQYCDDMFLTECHRMAAREKHRLAEVAEKEAAERAEKDKKNKRPLNGATRTSARVNGLAPEFGMTDLAAFEKNKRKRGSSAEKSDTQSGEEERGRKRVKILHPLEYVSAPEEMQVDYNAPITMPTPMLEDVFSGPPADPASLPLIAHAMPSGAIPPIKSPSPSGDVFGPHGLIPAPPNDAHAHFVDEPVNTVFSAAVASSPIPAEPARSPSPALPPPVFTLDPGLLSALQDQLVHSTVDLNVEELEQLRALGLDRIYRARGEWDRDPVVQGLVWFVRAFVAEVNGEYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBL4</accession>
    <name>M5GBL4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FES1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630346.1">
        <property type="nucleotide sequence ID" value="XM_040769893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBL4"/>
    <dbReference type="STRING" id="1858805.M5GBL4"/>
    <dbReference type="GeneID" id="63684955"/>
    <dbReference type="HOGENOM" id="CLU_046722_0_0_1"/>
    <dbReference type="OMA" id="LHWSIAN"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="35323" checksum="E4643DAF58426D8E" modified="2013-05-29" version="1">MESLLHWAIQHSDTTTPPTTSTLEAQARLRSLDPGIIETILGQPDAAKMRQSLALAQDQGRSRAERVQALDDLEMLVESLDNANDLAPLGLWKPLLGLLQSEEEEIRRAALWVAGTAVHNNPQSQSDFLALDPLPAVLGFVRDGEGETRARAVYALSGAVGHNPTAVGRMEELGGWRVLKNALEDPAPKVRVKVAFLLNTLLLLDTPQTQDQAHAYAHDTSVAPYPRAQKEFTTQTTKGRTRAAFKAEGIVDTLIEILSREGEEEEDLREKTGRCLLTFLEGGDDAWTGEQKETLRKALGVHSGGKLGLDQEEWERLTGSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCT9</accession>
    <name>M5GCT9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_113130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633314.1">
        <property type="nucleotide sequence ID" value="XM_040769570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCT9"/>
    <dbReference type="STRING" id="1858805.M5GCT9"/>
    <dbReference type="GeneID" id="63684632"/>
    <dbReference type="HOGENOM" id="CLU_056795_1_0_1"/>
    <dbReference type="OMA" id="MTLNNNR"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000022">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="410" mass="45294" checksum="C630A8144848D10B" modified="2013-05-29" version="1">MSTDAALLAEIAKLKGAINQHKSNQQHQPAIRSYPTRGGYGLRRSYRGAYRPPYAVPRPPAAEEKEVVIGGVAYITDGKKMTRKDVVNRPVQRAPSRPGSVGSPSAIGSDYVSLDMDGGEIKKPSAVSQSDLTAKRTRLNNLTLILNKAQAERYRRRQPSATKPGREKKQCPFFTRTGICTRGRTCRYQHDPEKVAMCPKWLKGDCPNGDSCPLSHQPTPQRMPFCVHFANAGRCKNGDSCMYPHVHLGATAGICRDFAVLGYCEKGADCDKKHVRECPDFADTGVCKNRHCRLPHVIRAKHAAKAKDAEDDAAVVSAGHPISTGKRKADFEDILDQTHGAKKQKVDESYASFADEPEFIPLTFEESEEDEEPQEGESEEDTDEDEEDDADNVEEEDDDVHDDADLVINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCW0</accession>
    <name>M5GCW0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628900.1">
        <property type="nucleotide sequence ID" value="XM_040772782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCW0"/>
    <dbReference type="GeneID" id="63687844"/>
    <dbReference type="HOGENOM" id="CLU_2979051_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="58" mass="5844" checksum="ABF99FEF33C57F52" modified="2013-05-29" version="1">MNAPRRVVFTGVVVTGQDGSVLCLRLGGGSSGSTTASFFDLFPPGEIPASPIVAGSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD26</accession>
    <name>M5GD26_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_93592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631086.1">
        <property type="nucleotide sequence ID" value="XM_040777171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD26"/>
    <dbReference type="STRING" id="1858805.M5GD26"/>
    <dbReference type="GeneID" id="63692233"/>
    <dbReference type="HOGENOM" id="CLU_016922_10_3_1"/>
    <dbReference type="OMA" id="RSAWDLC"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="49887" checksum="3C70CD048A96BDED" modified="2013-05-29" version="1">MSNPASSGALAKAAKPKYSTQEVMDMEQTYGAHNYHPLPIVFERAEGSYVWDPEGKRYIDMLSAYSAVNQGHCHPAIVSALIQQSQKLTLSSRAFYNSVFGAYAKKITQMFGYDMVLPMNTGAEAVETSMKLARKWAYMKKGVPEGKAIILSAEDNFHGRTIAVISMSTEAESRNGFGPFLARVGPQCPNFSAKDGGRIRYNNISDLERALEKHGKEVAAFLVEPIQGEAGIVVPDDGYLKRARELCDKHNVLLICDEVQTGLGRTGKMLGCEHENVRPDMVLLGKALGGGVFPVSAVLADKDVMLCIKPGEHGSTFGGGPLGCAVAIASLDVLVNERLAERAAVLGEKFRAGLQAIDHPLVETVRGKGLLNALVIDESKSTKGRTAWQLCLLLKDRGILAKPTRDHIIRFAPPLVISEEDLMHAVEIIKEAVFDLDELDSIPGENDEENGYHNVHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD97</accession>
    <name>M5GD97_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633569.1">
        <property type="nucleotide sequence ID" value="XM_040771634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD97"/>
    <dbReference type="STRING" id="1858805.M5GD97"/>
    <dbReference type="GeneID" id="63686696"/>
    <dbReference type="HOGENOM" id="CLU_082184_1_2_1"/>
    <dbReference type="OMA" id="HKPIYTP"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="178" mass="19757" checksum="42522575773B3C2F" modified="2013-05-29" version="1" fragment="single">MSHIIGNTALATARLWHHVDAKGRTLGPLAANIAKVLMGKHKPIYDRSADVGDRVVVTNAKHVVVTGNKADQIMYRHHTGRPGGLKEIPYKVMQEKRPDKIIKLAVSGMLPKNKLRDKRMRRLVVYPGEKNPSLRNITKRWDDGQMPGDSLSWTKSLPFPEEAKAALEAQKAGESPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDJ1</accession>
    <name>M5GDJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629342.1">
        <property type="nucleotide sequence ID" value="XM_040770143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDJ1"/>
    <dbReference type="STRING" id="1858805.M5GDJ1"/>
    <dbReference type="GeneID" id="63685205"/>
    <dbReference type="HOGENOM" id="CLU_1077778_0_0_1"/>
    <dbReference type="OrthoDB" id="4584900at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067687" description="Acid protease" evidence="2">
        <location>
            <begin position="21"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="27427" checksum="049EBB4832F771E9" modified="2013-05-29" version="1">MPSFFVLFGLLSALVFYASALPSGTRTYGIHSENAPFTNAERLQRGLPLKPPVRRTTLPGTHHSPSASASPSPSPSPSSSVRAGYVAVFSGDARIGYLQCSETCKVIPNDESYYATAVTFTLNPRGLPFDIMYDGASSPNIGGLVDAFSGDLGTRSTAEARLQSVPTTKPGDLPPSSVAEFSESAIWTYAPLNGLLVPTWINSFNDDVTTFIMADDKGNLFLSGDVSEFRVKHGTQSSGPLTFHFTNASAAARARASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDQ7</accession>
    <name>M5GDQ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_93182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631621.1">
        <property type="nucleotide sequence ID" value="XM_040777132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDQ7"/>
    <dbReference type="STRING" id="1858805.M5GDQ7"/>
    <dbReference type="GeneID" id="63692194"/>
    <dbReference type="HOGENOM" id="CLU_1023155_0_0_1"/>
    <dbReference type="OMA" id="HRKQPHE"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="112"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="29386" checksum="EF3930CEA2DA465D" modified="2013-05-29" version="1">MPQFPTPTAAQGQGYGSFPGYLSLSARGQTTAPKPSNPAPQTGVQGEPKRTPPSPPAQPAPKRSKTSSTDASSQSQWSPTQPCPTESDTKRAMAGMTSTVKTRPVALLSGEQKKASHIHSEQKRRATIRKGYEALCEVLLSLRDVVAAGGERKGKGRKRQEEEELGLGGVVKSEALVLTKTIEHVESLLAERNKLLTEHAHLASSLPAHERPPPYVPGQMTSLQPGARELRVWETPWYGGSGLPPAHMREAMIWMKGLGGEDEDEDEEGEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE28</accession>
    <name>M5GE28_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_99857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629817.1">
        <property type="nucleotide sequence ID" value="XM_040777632.1"/>
    </dbReference>
    <dbReference type="GeneID" id="63692694"/>
    <dbReference type="HOGENOM" id="CLU_243808_0_0_1"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1186"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1503"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1586"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1190"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1512"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1597"/>
            <end position="1613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1613" mass="176099" checksum="24A9FEB9D2B14B00" modified="2013-05-29" version="1">MCTCTRRVTGPPPGIERWTDGKHWSASRSKENFLFYEENSLGSEDPDAQQPNTEPGSSPDSDEPNVAVIDYITSSDAPGRLTKMTFFSWVKLPNDPPDLMRKWLLVSYWQMPHVKTLAKAYELEILLDHDIPRGMFFTSRAARNKQQDLPAAGTAYDVVLRRPTDLDALRWRKQQYYASGRPGPLPVGPGTRPDDVPGIYAGGGPWLPGGQPQSPSVTDARFRYHDQHQRTFPHHQTWRDELEDIPITERPPHWRPNAGGAQGGGSNALLTPGSDHASPLTFAHRQLPFNPPSSSARVTLPCPPQLLSIPYYTRCAPPPPHPPHPPTQRTNPARDTSLSSHSPASQQANAAFRPSTSIVPVQLSCQEEVWLTNNTLVANYCAPCRHNFNRACDLRRHVETIHVKGERGFPCTWPGCTQILNRKDVLQRHVRRQHEGKQKKGKGLQPRGVTVKGQMKLPSFREVVLRADRARARMDVGFALGIVARIYRELDPNRPHRTYKVQRLASESPANRLLVPPSGRADLLFAFFVRTNSSDPRNNRAPGSLPRPPPALPSAAPVEKEAREKSSIADLVALARVLGPRPALPMPAPTLKPRPYPNPEPRRTGEKWRIGCLLSVSDMAAFSSASWLPRELAFGFAFQNGFTLPSNADMETGPSSQTLTDDGSLSSRASTPLTSLPSSPSSQAALGPEDEGGTELEGIFAKPIPTSVDRSNAVLQQYFYVTLLPWRVAVCIVCHLAIEPKQAYRHYAEHLCRSRRPFRDKIALDAAMTELALQDAQLEIAPLVYARSGAIYASIMRMRPHPGKALSPACLVLCKPNIVLAGVISLATTLSRLHVQSDQLCSLYDGHPQENGPAQDPACELDLKVLHALAEVQYSKPDEWLRPLSKIANGQFEQSRERAASYICQLLLSAIRLRSDPERHPHLDLLLNDRQNELVGNLTAILRSIEPVNEPAAREAVKELLHSIITTRAHNTGLASYAVERWLILLSLRPDGSWRTVEAIGPIIGYLMHVVRDLLALHIFLEAGTSRGRQLDICTQIRPCHTDGEPYAWHCLSTLGGLINSIASNNPAWPNAIWSDGGKSIWYSEVTLSLEALRAGIVNIVSATERDFEALAHAKQDIGYSFLTDPANVNMLQARVHLGLINDLIELDMSRVRRAPPLIRLGELEADARSGCAGWACASPGRDWAGSEIASERKGEGTPRFRPRPSHSSTEPTCSSSARRMARRWTRTIGVAHPASCASSGKPEGRWCSSTPSTLATASIKHSATSSLAQPAPGYGRPRLPLLQRAVFDGRSDAAGRGGGELLPFGQLAGPGLPGAAGAAGVDFWPYEPPVPPPLATEGALPDGSDAQLLFAHLISRTLLTPSSPASPSPSTLRLCASSAASSSRLAYLHMNDADPPEPQRRLHNHVHISAPFILPSALHFKQTPALRSSLRSAAQHASQQTIIEHGGTLEVTVQLHEPVTRFLWDVDTRERNREHRVIVPVRTFVRDNNFWLPLPGTTLVLDGTGKSGVGEGEKGDAGEKQKRKELGEAPARARRCGRGGDVPARPSHPGPCGRGTVPLPNGRAMEPVGRLAGRTWVFVTGLPGSNATGNARGHRQGAGGRGAGGAGPVHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEF6</accession>
    <name>M5GEF6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cep57 centrosome microtubule-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_115426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630092.1">
        <property type="nucleotide sequence ID" value="XM_040770003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEF6"/>
    <dbReference type="STRING" id="1858805.M5GEF6"/>
    <dbReference type="GeneID" id="63685065"/>
    <dbReference type="HOGENOM" id="CLU_007735_0_0_1"/>
    <dbReference type="OrthoDB" id="76453at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024957">
        <property type="entry name" value="Cep57_MT-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06657">
        <property type="entry name" value="Cep57_MT_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cep57 centrosome microtubule-binding" evidence="5">
        <location>
            <begin position="755"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="195"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="469"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="330"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="639"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="831" mass="92766" checksum="A12D892AAEAAA8FD" modified="2013-05-29" version="1">MARRDSQRPDPLDDYVQRPPIAKSTSERERMIAERTLESHLSVVYQPSPAGTDDDLSVEYGRTRPLSPVNHEASFMSFSAQAPPHIAADYSHMIDDRFGPVGLDDSLGLTGLDISKSSAGHHMANVTLHAGFGGKATSPTASNIAFEPSRDVDDIKKGGHMWAQNGREIHDNSPRATRSGRRKLVEALPSNFSPKRVAADLPRKHPLMMESPKYPTRATRTSHEKGNGVSSPLQSPEDGPSSAFGRHARTLRHDMGLANAGSEQLPKVASRPSKYGKGDSIQLPDLTGLTSAVVTPAKPHVFYLQAQTHSPMEREVLAERRRHCEAQQRMSAHRDELDRLSGEVMEKEAEIADLQCQLRTERAGRYSHTNNGSDRIAELERLHSNLDSLRIELVRAEETLRKQGSVLEELRLEKQRDEERLRDMQRAYDRTFQDLRRKREEVGRLQRDVARLKAHYENMKALWNRHIKEQQQHQPETMGQEGIEQDDSSVDDAGESPYAPTAPAWRTERRQLSAVTEEDDEDLQDHPDEAHGGPAVPEMSTGSVSSLGTPVDPPEPDSPRFNQSFHNTSIVSDLAGPSQGRQKPLTSAGDVADLDDEVAERRSFRSLDSIHDSPPLMAQSRLPEPRQRPSSAPPLSSRLTGNRQPLQPHVTTSLQNAPVPPSSLQDSTLPRPRLKDERVERLFHVSGVHDAVHCWRCQEPHEGTSQGRGSTCAVNIPSLVHRMGEGHEAISIIVIRALEEEQRRRALTHADDGRTSQELLTNAIKDMEGDFTHYRSVYSELAEQYGVIAPKNRIRRNILAEHLGEVISILERKGDLIATLYDSLGNIQRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEJ0</accession>
    <name>M5GEJ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication protein A OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_106464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630197.1">
        <property type="nucleotide sequence ID" value="XM_040768273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEJ0"/>
    <dbReference type="STRING" id="1858805.M5GEJ0"/>
    <dbReference type="GeneID" id="63683335"/>
    <dbReference type="HOGENOM" id="CLU_345823_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A OB" evidence="3">
        <location>
            <begin position="481"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="817" mass="88843" checksum="33E08E29F48F02F6" modified="2013-05-29" version="1">MLSPKLNKYIEEGGIQSGAFLQIESVNRKTVAGYRSITVTRGVPVGTPGDICGSPTEISLRVGAIVPTDLVVGTTPPSRARTASRTSFRRSSPSKSHATISDGTFALLVMLSPKLNKYIEEGGIQSGAFLQIESVNRKTVAGYRSITVTRGVPVGTPGDICGSPTEISLRVGAIVPTDLTFEPVEEPVRYSLVPKDRADGGYLRSNGGSKQQPSASQPGGEGRSVTIKSITASKAVANGGQPQGRQAYGGLNKNTKVISMHPNAKVSVPNASSNIQASTSTECQPKSSSAATGSSAANGQSPASANAVSTVKTTQHFNLSNFITAAALEHVEPTRIAFSELNAGLRFDWTTYGRIYEISGPHRWKNETKEGIILTLKIVDKDRNKMLLGSFDPVAIERVMAEAVVGKVMKLSNVRVCPVKEEFLQPDILPLQMMLKYNSTFSFPNSVRPSGSKGGHFTDWFLGLARPAMPMQLTGIHLLRGLEFKSRVNVLGVVLHVGQVASFSKKKCVAGEEAEGDDRDDTAERRRLEVQLVDRSLFVVCLTLWDQKADDFKVKRGDVLLLKKVDVVNHGGVSLNAFKFTKLDFEPNISGVTELKDWYSALPEDPALKHVSSGYSASAGLRDGIVPRSSPLSIKDVLESNLGHGARVDTFHLEEAITGFDCQTLYEGCRHPDCNRSLENREHACGIASHAVQSEDDGEKRTKAKEMLKIMAFSPVADEILNEAPEELVKVRDNNEGGYEALLPSKLGTIYKFTIQARTRRWKNVDTGKFYTELQYHVVAAHLKEEDEEEQPVEEVEDEGDGDGEEENAGAKWSYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF03</accession>
    <name>M5GF03_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_45810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632756.1">
        <property type="nucleotide sequence ID" value="XM_040774665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF03"/>
    <dbReference type="GeneID" id="63689727"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="RLFQATW"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="26151" checksum="80D7F37EE783BC3A" modified="2013-05-29" version="1">MSPTVYLVSGANRGIGLGLVTSLVARPDVVVFAGCRNPAGASDLTTLASKYPSKLHIVKLTSCDEVDNKAAVEEIRNVVGRLDVVISNAGIGNFFGQALETPPEKMDEHFHVNVTGTLVLFQATYALLKASTPSPKFVCISSMGGTIGSGARFPGGLLAYGASKCALNYLAVKLYFEHEGLICFPIHPGELKTDMSNFAKQHPLLDLMEAMPVDEGVKGILDVIDHATRKPDGLGFVSYDGTALPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFF0</accession>
    <name>M5GFF0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_86010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633111.1">
        <property type="nucleotide sequence ID" value="XM_040776753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFF0"/>
    <dbReference type="GeneID" id="63691815"/>
    <dbReference type="HOGENOM" id="CLU_018303_1_0_1"/>
    <dbReference type="OMA" id="RVCYVQV"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067730" evidence="8">
        <location>
            <begin position="17"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="605" mass="66687" checksum="019A7085C1ACF95F" modified="2013-05-29" version="1">MSIWGLIWLTISMAGAQIAWVMELGYGTPFLLSLGLSEQLTSLVWLAGPISGLVAQPLIGAISDSSTSSWRRRYWIVTSTIALIISTLVLAFCVGIAEILVDIFTGGKAQDPNVGKTIKNTAIALAVTSFYVLDFALNALQASLRNLLLDVTPAEQLTIANAWHGRMTHAGNIIGFTLGFLDLGTWPALAFLGGDQFRKVCVVSLIVLVITIWITVATQKEEARQEEFKFSSGSELWDIVNNIYRAVLTLPKPVRRVCYVQVFSFMGWFPFLFYSTTWVGEVMAQEIDADPDVDTATRAGELAMLFYSIMAVVAGTLLPYLAARDQRLLEVVKDEREDAEIARIRIMVHSWKIEAARKGEPLKLPTMPFMLRNIWTGALLLYTAVMMSTFFVKTVFQATIAITLLGISWAVACWVPFAIIMEYLKEMDDQSERNRKEDLNSASRASGPRDPESGLLARPGHARVVSTPARLYQQDEATDRTPLIRRHSIAEPGPLSDMPMDYTSSQPAAGGTVLGIHNLAIVFPQFVVALVASAIFKAVDSVTVAPDDPTGGGYVYYGKNGVAWVLRFGGICAFVAALLTRRVPPTKTEKLMRRRRAEMNFIDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFF2</accession>
    <name>M5GFF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630992.1">
        <property type="nucleotide sequence ID" value="XM_040768050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFF2"/>
    <dbReference type="STRING" id="1858805.M5GFF2"/>
    <dbReference type="GeneID" id="63683112"/>
    <dbReference type="HOGENOM" id="CLU_776174_0_0_1"/>
    <dbReference type="OMA" id="RPYANGM"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="357" mass="38540" checksum="13FD7028DB316F5D" modified="2013-05-29" version="1">MSIHTPPHTPTRPHPPSYPLSPPQPPPPPRPQLQLMTPKRATTKSYIPTPAASRPSSPIPSLTIDTEKPRRSSTSISRTPSSLSLPLPLPLQHTSLGLTKRHRRLTALLLTSLFLLLALAYSLFHLSSTGRLLPIDVLLSHPSSPPTTPSTYNARPKPPPLPPLLLSPEEELAALVSHLASVLDTNSLPAEIDPSLPIDPDYLLGFDTRGPDRETVDAKVRDMVADTWATLPVVVFTKVPPLPPARSFVAHPLQAGPRSREVLSILSSYSLTPAPLEISLDSTRPDSPLLLRALARLTASSLPTSSTEGEVSLPLLLLGGKAVHRTVRNLHANGELRGMFREAGVGVGRNPLKDTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFI4</accession>
    <name>M5GFI4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CCP1</name>
        <name evidence="15" type="ORF">DACRYDRAFT_20779</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631047.1">
        <property type="nucleotide sequence ID" value="XM_040772078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFI4"/>
    <dbReference type="STRING" id="1858805.M5GFI4"/>
    <dbReference type="GeneID" id="63687140"/>
    <dbReference type="HOGENOM" id="CLU_036959_1_1_1"/>
    <dbReference type="OMA" id="QRKWNGP"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 13 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="165"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="375" mass="41695" checksum="8737EE31377BE2EC" modified="2013-05-29" version="1">MFASVLRTQLRRPLVGAAGRMPAVAPVTRNVIRARGYATEAGGSSNTLLWVLGAAAAAGGGYWYYAAGSTDVMKKEAESAVKSASQAVKAATKFTPTKDDYQKVYNDIAELLDDNDYDDGSYGPVLVRLAWHSSGTYDKNDNTGGSNYATMRFPSEAGHGANAGLEVARTKIEEIKQKYPWMSYGDLWTLGGVCAVQEMQGPKIPWRPGRIDGFAKDATPDGRLPDASKAADHLRNIFYRMGFDDQAIVALSGAHALGRCHRNRSGFDGPWTFSPTTFTNDYFTLLMNERWTWRKWDGPKQLQDKTKTLMMLPSDFALVQDREFKKWVKVYAGDNDKFFSDFSKYFSELLELGVPRAQFVASEPWIMKTIDEQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFM7</accession>
    <name>M5GFM7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_44699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633346.1">
        <property type="nucleotide sequence ID" value="XM_040774603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFM7"/>
    <dbReference type="GeneID" id="63689665"/>
    <dbReference type="HOGENOM" id="CLU_078023_0_0_1"/>
    <dbReference type="OMA" id="MEPGWIM"/>
    <dbReference type="OrthoDB" id="41238at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:protein-N-terminal-alanine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF5">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="66"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="252" mass="28215" checksum="875E3F03C5E70FF0" modified="2013-05-29" version="1">MTFVNNHVSPTTDEDATFGPEPYDVNFIFPILPLSLESPRIKLIPFIPKLHAELYFNATVDCQFLYDFLPFSMATLKSILIFAEGMRSSPGKILFAIFDKTLLPESLSAHPSRSFAGIIGLNNANLDYLSVDIGPIVVLPAYQKTHVATHSVGTLLRYCLELPSAVAHPGLGLRRVTWLAKPDNIASIRLAEKMGMIREGVLRWTYVVESPGTRTRDGDPNYKLGRDCLLLTMTCEDWEMRGSELVKQKIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFT1</accession>
    <name>M5GFT1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631297.1">
        <property type="nucleotide sequence ID" value="XM_040772157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFT1"/>
    <dbReference type="STRING" id="1858805.M5GFT1"/>
    <dbReference type="GeneID" id="63687219"/>
    <dbReference type="HOGENOM" id="CLU_027164_0_0_1"/>
    <dbReference type="OMA" id="LVCTITW"/>
    <dbReference type="OrthoDB" id="2524557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF41">
        <property type="entry name" value="HL07962P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="62"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="533" mass="58981" checksum="19D2C1E4933061E8" modified="2013-05-29" version="1">MGVFPPPHHSRRSISSPSWNVEDSGSGTEDMYEHVQRSESGLDEGEEIEVDPTFRRDNEWPGTVRINVENTTFWAHKDVLIFASPFFAAALSGNWAETGRPASLSSSIITVTRSSTPPPLPSPSHGPIPESVSPTPDSPEPSPGMFPADLEAEQESDGATDPQPDPRSSPPPQTTLHFLSPSQCKECASPLPDSATPGNSSGEDEDPAEAGAEADPSVHRAASLRALSSGPPRRSTMEEKRASKGKRNVRVSWDGRAGRRPRPVTRMSGCAEAVIDLKEERASAFHDFLKFVYPHLECTITWNNVENLMHLSQKLISPNLQSACLSFLLSHAAGKPIKALRIAELYEEEELYREASRFVLDNLGGWPDSELRTLSRDTLLKLEKRRTWFLERLLKLGVTPIAKDYTCCSSCPDPTTCARHLEEKWRQGYLSLLRFGPPQPSMVFRYLRQLELSPPLTLTHLSCQTCAKTYISTLFDRMFSLGVRGSGTDTTPLGARVGVASGIAGPRRHFLYCALRGEREWKPASTRGEVYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFT6</accession>
    <name>M5GFT6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631312.1">
        <property type="nucleotide sequence ID" value="XM_040772164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFT6"/>
    <dbReference type="GeneID" id="63687226"/>
    <dbReference type="HOGENOM" id="CLU_2512588_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9531" checksum="7B0534A1BE7EF8D7" modified="2013-05-29" version="1">MYVNGHVVVISFKIFEITPTVQRGSRNTSSIHYEAVNSEIIVICTWSKGATKSTYLAKCHHTYLLTEEHFALVSPNVRKAGGKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGB1</accession>
    <name>M5GGB1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632072.1">
        <property type="nucleotide sequence ID" value="XM_040771646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGB1"/>
    <dbReference type="GeneID" id="63686708"/>
    <dbReference type="HOGENOM" id="CLU_2960690_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="59" mass="6438" checksum="547052D6135395BA" modified="2013-05-29" version="1">MGRQNSGSMVVGICNGFRSEILAKCSLSEDGGVYRRLLSQRKTNSSGPQLFHCRASALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGK9</accession>
    <name>M5GGK9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_86672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632562.1">
        <property type="nucleotide sequence ID" value="XM_040776783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGK9"/>
    <dbReference type="STRING" id="1858805.M5GGK9"/>
    <dbReference type="GeneID" id="63691845"/>
    <dbReference type="HOGENOM" id="CLU_013967_0_1_1"/>
    <dbReference type="OMA" id="IHGPASF"/>
    <dbReference type="OrthoDB" id="2100241at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF2">
        <property type="entry name" value="ALKALINE PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G03860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="3">
        <location>
            <begin position="389"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="745" mass="83572" checksum="63B8A422BBC8F87A" modified="2013-05-29" version="1">MEVDKKVKVEEKETNGTKGTVGEPKKTEAKEIVVVEKVETIVRDPVVSVTDSFANLALAFPSSFLSLRVSALLINLILMLFTLDFIYTPFIQTFPDLAYARVGAVTPHSARLVLRYPLPPLLEVMPAADELNREGEVEGVERLLKQESWEVHVWWRENVNVQAIGIEVEGPVELSWNEGPKVELLEENDWVGVAQLDKLLPATEYEYRFAFANSTILPVSKGQLTFRTFPAGNAAHFKFIASSCLMPNFPYRPSLSSTPSIRGFDLLASVLAKEPKRNVYGTEPESEPVSASPKTAPSPEAPAEEATTAMDNEPTPEPTEVVQQEEVPQTPLAESVTLVSETPQEAASARLPVSSVPSLPPLNLENAVSLFKSVLKGKPKEEVPESDANTEFALLLGDFIYADVPRYGGDDLEKYRRLYRRVYASDNYRKIYEHLPTLHIYDDHEITNNYVGHDNDSAAPFPRANNAYEVYQNNANYAPIRPGGNYYNFEYADSAFFVLDCRRYRTNVEQEIGDKATMLGEHQLSDFNHWLSKVNNTHTFKFVVSSVPFTTLWHGIDGQTDTWAGYPTERHEVLQKMASVPNVVIISGDRHEFAAVASAGRAGGNVLEFSTSPLNQFYLPLYSTFDTAAKTTATWTRPVERVVKNEQGEDEIEVTEEVVPEEKVLRYVREGQHKWGSFEVDTRDEEHPKLIFELFIDGQRAWRLNIPAKPVKKHPHSTALGMGRVIGQNFKHAMEAIGLWRALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNY0</accession>
    <name>M5FNY0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623531.1">
        <property type="nucleotide sequence ID" value="XM_040769446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNY0"/>
    <dbReference type="GeneID" id="63684508"/>
    <dbReference type="HOGENOM" id="CLU_2196868_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11784" checksum="E529410FF236EE68" modified="2013-05-29" version="1">MALFWGILALCKQNKQSLEALARTSPGRVRFNSNNDILGTGPDGEGMDLVGKAMMPVRELTRVFNGIRNGAYTSECMVHESHGTPSWSGLHNTPDDTDSMALLDCTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP10</accession>
    <name>M5FP10_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prefoldin alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_111116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625033.1">
        <property type="nucleotide sequence ID" value="XM_040769177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP10"/>
    <dbReference type="STRING" id="1858805.M5FP10"/>
    <dbReference type="GeneID" id="63684239"/>
    <dbReference type="HOGENOM" id="CLU_091867_0_2_1"/>
    <dbReference type="OMA" id="QAKFKAC"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="20114" checksum="3EB3FFABE5821A5A" modified="2013-05-29" version="1">MSQQTQSVSVTDLELPQLQDVKRQLDEEISHLTNSYAQLKQAHSKFKTCLDCVKEVRPGNARKTILVPLSSSLYVNGKLSDPEKVLIDVGTGYYVSKVCLSTPTACHFNLSSISCIHLFRQSLTSKQTRDQAASHYQQKIEFVDGNLKKVQETIEKKQENLNLVLQVMQMRMGQAGGAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP36</accession>
    <name>M5FP36_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_91165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625078.1">
        <property type="nucleotide sequence ID" value="XM_040776996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP36"/>
    <dbReference type="STRING" id="1858805.M5FP36"/>
    <dbReference type="GeneID" id="63692058"/>
    <dbReference type="HOGENOM" id="CLU_008539_3_0_1"/>
    <dbReference type="OMA" id="GSADTEY"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF72">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067013" description="alkaline phosphatase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="2">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="655" mass="71533" checksum="9B18F54E3584B69D" modified="2013-05-29" version="1">MLSVVPVAVSLLSLAALGGAQTFQRLGTCPSLGCIFPPDQTDFLPGAFFDIRAEIHAPVNGSEANGGVPDTAFGFTLEKVGSDAKPISAFFNVNEPNMESWNFTWFEDLFAKDANTPSLVRVASKAWRKVSLNEPGDYVATLAYYNGSKTVANWHVRDQSPARKAKNILLFIGDGMTTNMITAARLMAHKSINGKYQSLMAMDKFPVVGHQMTHSIDSFITDSANSATALYTGHKSTVNALGVYADSSKTPYDDPKVETIAEIFRRKMDGGVGIVSTAFIADATPAALTSHTRDRNQYGPVIDAYLNGIVNYTWTNWSGPDVLFGGGAEQFYPGPGSFQGKDYYLEFEKKGYQVIWNKTAMQAASNDTKTLGIFSVNNMAKWLDRNVYTENLKNQKNSPDGKGTDALDQPGLKEMTVKAMEILQARSGDKGWFMMSEAASIDKQMHTLDYDRALGELLELDDTIRASIEYLRETGELECTQILVTADHGHGFDVFGSVDTKYMNAASTDRQKRGSIGTYQNSGLSQYTFGGNLTYSEGVYFPARWDPRYTLAEGLGAHPDERENFEVVKPGPRLPAVNISAEHPTDFYVNAKETQTGFIVNGTLPVNNDQGVHSLTDVPVYAMGPCQEVFGGTYGNIDIFYGMANCLGLGTPSTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPD3</accession>
    <name>M5FPD3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623886.1">
        <property type="nucleotide sequence ID" value="XM_040774151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPD3"/>
    <dbReference type="STRING" id="1858805.M5FPD3"/>
    <dbReference type="GeneID" id="63689213"/>
    <dbReference type="HOGENOM" id="CLU_023111_2_1_1"/>
    <dbReference type="OMA" id="WHEYNVF"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="453" mass="48196" checksum="7D0A6C884A92E488" modified="2013-05-29" version="1">MATDAPIGLILITRHGDRQGFYQDPTSYTASNTVITPLGELQEFQSGTGVRVRYLTPGGASYMPALSPQIPSLTQIDVRADGGGEGGVIVDSAYAFMQGMFPANTTAQTITLANGTTVTSPLGGYVYVPVQSVMPTKDYTLEGFTSCNTFAAHNTAFYNSPHFLQVQSDNMAFLQSLEPILGPDRNISLANMYNIFDYINVNNIHNATFHSMVSNDVMEHVRALTNYHEYGVFSDVTPAGIGNIAGQAILQPMLTALNEFQNTSSPVRFQYLGVSYKPFLSLFNMTQVPNQDIVDYASVLAYEVRNTSSGFTIRANFRNGSATAMDGSDILPLSMFGNAAGADMPLQTFIDNLAPYAINNLIQWCNVCNQTTANGCNIALAAQAASLSSSSSSSGSGSVSPPIAGVIGAFVTLGVALILAALWFLATKFVKRPAPTAGGDNGSGEHLEKRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPI8</accession>
    <name>M5FPI8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Opioid growth factor receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_25232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the opioid growth factor receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624001.1">
        <property type="nucleotide sequence ID" value="XM_040774073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPI8"/>
    <dbReference type="GeneID" id="63689135"/>
    <dbReference type="HOGENOM" id="CLU_032134_2_0_1"/>
    <dbReference type="OMA" id="WWANCLR"/>
    <dbReference type="OrthoDB" id="9030204at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140625">
        <property type="term" value="F:opioid growth factor receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006757">
        <property type="entry name" value="OGF_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039574">
        <property type="entry name" value="OGFr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14015:SF2">
        <property type="entry name" value="OPIOID GROWTH FACTOR RECEPTOR (OGFR) CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14015">
        <property type="entry name" value="OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04664">
        <property type="entry name" value="OGFr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Opioid growth factor receptor (OGFr) conserved" evidence="3">
        <location>
            <begin position="30"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="31994" checksum="5BFD0A1DB578F30E" modified="2013-05-29" version="1">MVLLSPSAILPRDIKDFIASYPSQLRTSPSQSPNYSFYTAPSSSKHGVMAMHQELRGDWDELEWRHNFVQWMFPIREQGMNPNATPLQVHEIGRMKQSEEIMRRLRVSYEIMLEFYGMRVLDPETGELDITLEPEKSDAGWPARFYNLEHRMHNYLRITRMLKCLHELSHPHYVPSFLLFVLALQHPSTSDDHSQPRLRSARLVRSMDGYWRHCIRDEVVREWVRSTIERVREDGHWGLGEYRKAVEGYRKTGRYGRDSGDGSVEQGNAMGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPQ3</accession>
    <name>M5FPQ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623452.1">
        <property type="nucleotide sequence ID" value="XM_040774250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPQ3"/>
    <dbReference type="STRING" id="1858805.M5FPQ3"/>
    <dbReference type="GeneID" id="63689312"/>
    <dbReference type="HOGENOM" id="CLU_1310080_0_0_1"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="210" mass="22621" checksum="87803A8707FF1AE1" modified="2013-05-29" version="1">MGEVGRGIFGGECQGVRRYIKYSGEIDRADAEICPHSIPLAWTGTSTLIQLTSFNSPHSTHLIQLTSFNSPHSTHLIQLTSFNSPHSTHLIQLTLQALSPPLLPSNFPQPQISRCGKAAMRNAATAAFLDAGSVSMRDIVCACAVGTRNGALVLDPTERNGRFWFPIPRNSARRAGVGRIGRGRRRLGKDRKKRATDGGGDGEGLYASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPU4</accession>
    <name>M5FPU4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624216.1">
        <property type="nucleotide sequence ID" value="XM_040770789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPU4"/>
    <dbReference type="STRING" id="1858805.M5FPU4"/>
    <dbReference type="GeneID" id="63685851"/>
    <dbReference type="HOGENOM" id="CLU_094640_1_0_1"/>
    <dbReference type="OMA" id="ASSRWQI"/>
    <dbReference type="OrthoDB" id="9975758at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22247" checksum="FBE9F686D4E46DB7" modified="2013-05-29" version="1">MAAPATASKTVQIYQPSGKDGVPSHPSLSKAEFPIDAFQGKWFVIQSTLGIWKTRKDVTITYTPHTPPPNLAYNDHVQYRSTSSPSSKPLCSIVGISTLLPTAAQSSTDTQPHQEHGAHFKWRGSGWLRIASSKWQVLGYDLQEGWVVTFFEKTLFTPAGLDVYARQPGTLSSERLSEIVKATQSLGGEAGKLAEGFFEVTHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR81</accession>
    <name>M5FR81_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isopenicillin N acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626493.1">
        <property type="nucleotide sequence ID" value="XM_040773341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR81"/>
    <dbReference type="STRING" id="1858805.M5FR81"/>
    <dbReference type="GeneID" id="63688403"/>
    <dbReference type="HOGENOM" id="CLU_037787_1_0_1"/>
    <dbReference type="OMA" id="ECTSIGF"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047794">
        <property type="entry name" value="C45_proenzyme-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047801">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45_hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040521">
        <property type="entry name" value="C45_proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180:SF1">
        <property type="entry name" value="BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180">
        <property type="entry name" value="PEPTIDASE C45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase C45 hydrolase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="341" mass="37965" checksum="BAF29A9B58C8A1F5" modified="2013-05-29" version="1">MLVINCKGTPREIGLEHGTKAATHIRAGIQCYQTQFMEMSNVGWEEVLRISKRFEPAMRERYPWLMEEIEAIAEGAGVSYLEIMALNFRQEIIFGMYADGCTSLGWKTSEKSFLSQNWDWLIDQKDNVIVLNIDAPGKPRISMGTEAGIIGKIGLNSDGVGVCANGIRAKGVDYNGTPVHICRRLVLESQTRDEAIAKIEKYGTAAAGHMLVGDATGCIGLECTIQGIKKLYPDSKGRIMHTNHLLAEHEGVVDYQWLEDSPRRLRRLTELANELGRNPTQVEISELFKDESDLPCAINRIPSKEEPMETLFNIVMDLTTATAVLKFGRPTQPDDVLILAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRH4</accession>
    <name>M5FRH4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625176.1">
        <property type="nucleotide sequence ID" value="XM_040773821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRH4"/>
    <dbReference type="STRING" id="1858805.M5FRH4"/>
    <dbReference type="GeneID" id="63688883"/>
    <dbReference type="HOGENOM" id="CLU_927565_0_0_1"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="32365" checksum="C6A0B463BC0AC03D" modified="2013-05-29" version="1">MYRHPGVASVDLVGATLRQGTFIRALYSLGWLTPARFAADPTPLLRAIARFHAWLDLLSLHPAAFLVPTLDIDLAWHTLMLSPGRYRRDVFGLVGRVVEHEDKVEEGVLGEGFDATGRLWKARFGVPYSYCGCPPSTASKLVDRTSLSNIRATLLPLRGRSDSAASARSTASLPGANAPGSASGVPRPTRADLAPDEKDAPLSHASEHNSILVISHSQCAKARQEREMDIAKRGEALRRAAAKGKGDEWEEGIARRSLGHEPAFLLPLPPAGPGVQNDSALFYLPLVLLPLPHACVVRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRK5</accession>
    <name>M5FRK5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-alpha-glucan-branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycogen-branching enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_25006</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624527.1">
        <property type="nucleotide sequence ID" value="XM_040773960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRK5"/>
    <dbReference type="STRING" id="1858805.M5FRK5"/>
    <dbReference type="GeneID" id="63689022"/>
    <dbReference type="HOGENOM" id="CLU_011131_2_2_1"/>
    <dbReference type="OMA" id="YEMHLGS"/>
    <dbReference type="OrthoDB" id="196493at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000001">
        <property type="entry name" value="1,4-alpha-glucan branching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000250">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000003">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF3">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="12">
        <location>
            <begin position="177"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT97629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="677" mass="77738" checksum="7194137FFD4C9ABD" modified="2013-05-29" version="1">MAVLDSAPLLKLDPWLQPYIHPIASRYAHFMKWKTTIQDTEHGYDAFSKGWLKFGLNVAKDGSITYREWAPGATEASLIGDFNNWDRSSHPMTKDMFGVWSITVPPVNGQPAIPHDSKIKISMISSNGERVDRLPAWITRVTQELAVSPAYDARFWNPPTGQKYTFKHPRPPKPQDPRIYEAHVGISTPEPKVGTYKEFEQNVLPRIRDGGYNTIQLMAIQEHPYYASFGYQVTSFFAASSRYGTPEELMSMIDTAHFMGLTVLLDVVHSHASKNVLDGINEFDGTDHLYFHGGGKGRHDLWDSRLFNYGSHEVLRFLMSNLRFYMEEYMFDGFRFDGVTSMMYVHHGMGTGFSGGYHEYFGPSVDEEAVVYLMLANDMLHSLYDGVITIAEDVSGMPTLCLPTDIGGVGFDFRLSMAIPDMWIKLLKEKSDDEWNMGNIVHTLTNRRHGEKSVAYAESHDQALVGDKTLAFWLMDKEMYTHMSDLTPLTPIIERGLSLHKTIRLIVHALGGEAYLNFEGNEFGHPEWLDFPRQGNNNSFHYARRQWNVVDDHLLRYKYLNEFDKAMNWLEDKYHWLRSPQAYVSLKNEADKVIVFERAGLLWIFNFHPTQSFTDYRVGVDTPGKYKVVLSSDEKRFGGFDRIDMNGEYFTTPMSWNNRANWLQVYIPTRTCLVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRY3</accession>
    <name>M5FRY3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_111362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624742.1">
        <property type="nucleotide sequence ID" value="XM_040769220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRY3"/>
    <dbReference type="STRING" id="1858805.M5FRY3"/>
    <dbReference type="GeneID" id="63684282"/>
    <dbReference type="HOGENOM" id="CLU_008455_11_0_1"/>
    <dbReference type="OMA" id="VIFTMPE"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF173">
        <property type="entry name" value="MFS-MULTIDRUG-RESISTANCE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="398" mass="44065" checksum="E89E27CB2790515F" modified="2013-05-29" version="1">MVEFDMSEELATLTIAIFVVGYCVGPLLWGPLSESYGRRPIFIIAFVFYTIWQVAAALSRSTGQILVFRFLGGTFAAAPLTNAGAVLADIWDADTRGEAMAIFTLAPFAGPALGPIVSGYMSVAHVTWRWLFWLLSIFAGACTVAIIFCLPETYTPVLLVSRAKTIRLKTGETRYFAALERAEVSLRKRLSLVLGRPFKILFLEPMLIAITIYMSFGHGMNSGVSGLMFLPLFLGGCAGVALYIWGFNPRYERFMRMCDPRPVPPERRLEMAIVGGPLFAISFFWFGWTSYPSISFWSPMMATFPLGIGITLIFLSLFNYIIDAYLLVAASALAGSTVVRSSFGAGFPMFATQMFDKLSPRWPSTLLGCIALLMIPIPVILMRYGAFLRRKSKYSPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSS0</accession>
    <name>M5FSS0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625192.1">
        <property type="nucleotide sequence ID" value="XM_040773831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSS0"/>
    <dbReference type="STRING" id="1858805.M5FSS0"/>
    <dbReference type="GeneID" id="63688893"/>
    <dbReference type="HOGENOM" id="CLU_023205_10_1_1"/>
    <dbReference type="OMA" id="ITYQAYW"/>
    <dbReference type="OrthoDB" id="5357513at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="30707" checksum="5597E5213AA0047D" modified="2013-05-29" version="1">MNKWGLLIRFFRKKERTTELIVQAVLQGFRGIDTACQPKHYREELVGEALRILQESHGIKREELFIQTKYTPIGGQDQSQPLPYDPTTPIGEQVRTSFALSQKNLGTGFIDSLLLHSPLDSPEATLEAWQALRQLQQEGKVGLIGISNCYRIRALLALEREAQVNVVQNRWFEGNGWDKDVLDYCNENDIKYQSFWTLTGSPSLLRHPLLQDIALKHQCTPAQAVYAIAQSFGVVPLAGSTSEKHMLDGVRARDLPIEPEDSEIIRQLIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSV4</accession>
    <name>M5FSV4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA polymerase</fullName>
            <ecNumber evidence="9">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_80817</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="9"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627488.1">
        <property type="nucleotide sequence ID" value="XM_040776473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSV4"/>
    <dbReference type="STRING" id="1858805.M5FSV4"/>
    <dbReference type="GeneID" id="63691535"/>
    <dbReference type="HOGENOM" id="CLU_008698_1_1_1"/>
    <dbReference type="OMA" id="NYPYKKP"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000001">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase X" evidence="10">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="269" mass="31141" checksum="90FED3EE66CBA430" modified="2013-05-29" version="1">MEIIETGQLQRIQAEDTEEYRVCRLFAGIYDVGRKRAHEWWRMGLRTLEDVEKRKDEIKLTRNQAIGLKYYDDLQERIPRAEASVIFDKIKELAMTIDGNITLYIMGSYRRGAETVGDIDILLTRDPSDGRTHSGMLNKLIRLLHEKGLLTNDLAVPADTHSLEQKYMGIGRLPPDGKMRRIDVLAIPWDQKGAALIYFTGDDLFNRSIRLLAHKKGYSLNQRGLYGGIIRDNKRRKMTEGVIIASKTEKEIFDILGVPWREPEERRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSW2</accession>
    <name>M5FSW2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625287.1">
        <property type="nucleotide sequence ID" value="XM_040771325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSW2"/>
    <dbReference type="STRING" id="1858805.M5FSW2"/>
    <dbReference type="GeneID" id="63686387"/>
    <dbReference type="HOGENOM" id="CLU_288206_0_0_1"/>
    <dbReference type="OMA" id="QIFLVEC"/>
    <dbReference type="OrthoDB" id="3263880at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="825"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1067" mass="116579" checksum="E27EFDB2F0C529C3" modified="2013-05-29" version="1">MPSARGTRYNPYPHPHHPPPPHHPPPPPLSPLPPLSSNSSLNFSLPLSDEETKPFEQHEPEHGQDHAHMSSPPEQEEDSPEGSRRKKSHAQRQQFTACGACRLRRVKCDLKDVALSRPSDSSDPLQCTNCRQRQLNCVDEYSRKPAKMMRRGRRLQQAQAIYGIGSQPSPTFPQQQKSVIPLPTPEFFHSEWFRHFYFQRPIVDASEFPTFCTPGGPGLLGDSPDLISKSLIIWAQSYGVDHTGTVFSPTRQDLQLRVERCRPMVQELLEEVDRRGVLRKLSWDNVRLVCLLLPLTLDTLTPHARNAMYRAALSQAYELARPGVDPVRVDRAMDVPTFLKLRVLWYVLVFEGVKTALYGNPVILDEEVWKGCLPIPRTTPFEDGPQLRTRPTRSGVNGLGVGIGIGIGAGVLTRTAYVPADDLSALWGYALPPVDASFACRRIHAELTSDRATSRPTVDPRAVQKIWELLERCWQEFEELKSCNPSNVGDGASGMNILPAEERAMLASRWQIFLVECRKYLRKYDGCGADADTKADVVVLDALKLRLLRLTEEPSTCAITSDSPLPSPVDAHPSHPSQSQSQSEYNNVQHLITLAKAHSLRAAERGSAMLPWLLSTPLFQHDSTLVCRGVYLGARVLLEEGRAGAGAGEEVAYALEALDRMHWAFGDSLELWGKLREMIDVQQSAQSAQSQSAQQSQSQQQAHPAHSASLSGQRLRPLTIPTWATSTPYSHSHSHSHPHSHSHSPELPQLHLPLQPAFYEQEYDTYGMEGLGYGFVMPQGVDVGVGVGVGMQGVGVGVGVGVQGVGVGMYPTVQTQAQAHAQAQAQAQAHAQQPTQSQGQSQAQSQVQAQGQSQSQAQNQNQNQGQGGAVYPQDPLAPSDASYSDQVPPTHRLPAVQAGSGQPTPDSDSTPFAYSLPPPTNTSTGASGGGVGPAQPSASPSTVHSRPSSAHQYPYPQQLEFPMNTPGSGYPFSPNVHAGGVGVGVGVGGGGHYLQEYATEGFQLLDPEHSHSHSHHAQGYGYPYPLQHPSPSLMKNVDLDLDMHVDVEGVHVQFGQGTYHAEPFLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSY1</accession>
    <name>M5FSY1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625971.1">
        <property type="nucleotide sequence ID" value="XM_040771301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSY1"/>
    <dbReference type="STRING" id="1858805.M5FSY1"/>
    <dbReference type="GeneID" id="63686363"/>
    <dbReference type="HOGENOM" id="CLU_794581_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="349" mass="38165" checksum="73173A2B619BFD5E" modified="2013-05-29" version="1">MPYASAEHCSWSHRKAIAAANKIKHDQAKALLQDAEDALGKALLDISAQTGVSIGCLMANIIMQSHSGGSILQTQQGLWLLRRQRIALVQQESVILAQEKLAELKGDTAACAAAEAHLAPTQERRQLGLQINWKGRQQDTCKTADLFHQQGWLLLTLQNPSEVSNMADLQKIQGALDSGQCFFWTMLPEELQCRNAEREKEAEEKHHTAEVRKALTKPRAPASRKQPFPELDAEQHAAKSIIGPVVQCPAGSNSSMPSSQIQQTPSFLNAAMFPVPLPNPTSAAAQPCPAFPPPTKRMWTMPNAAMTAAQVLSVPKTSVNHLPFHDIMNTQQGINVAVLHNGLFFFAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT13</accession>
    <name>M5FT13_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_90694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626021.1">
        <property type="nucleotide sequence ID" value="XM_040776965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT13"/>
    <dbReference type="STRING" id="1858805.M5FT13"/>
    <dbReference type="GeneID" id="63692027"/>
    <dbReference type="HOGENOM" id="CLU_012350_0_0_1"/>
    <dbReference type="OMA" id="ERLRYMD"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="323"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="396"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="515"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="595"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="626" mass="68129" checksum="ABC8E586BB114501" modified="2013-05-29" version="1">MTPFAAGRSDSTRILKDLAPVIMTPRMIKGVASASSTISSRHLAPRASDFAALGRAPLRLTLHPRRITSADMQILEATPELLHADVPEPRGVEKDVSLLRGFQATIPSSERGKVRRRKVRMSEGRVGLAGRGAGERGLLTEENDEGERPRGTPRKGRNQRRKEREAGRVLSREELSTQVGEIRIDKENLHVRRALVNADIDEITQKIAALDAIREQLHQDLLRMQEEELELDDELTGVQEQLAEADSRKPEVPSAAARRKKGPAFLPSDHDDLPPGVAFMTLSHSSPITSLDFSEPYGTLVSADRSGSVRVWDLLEGEEIGRLRGHAGCVKALQVEGDVCISGGEDGAIRVWSLGRVEEAEAALEERTEKLNGHAEPAASETGEQTEQTGPLLHVLEGHSKAVTALYFEDTSLVTGASDKTLRQWDLTTGQCILTMDILWAISHPPVSPTIDGLSPSGLLAAASGSFSWPIPSTGEMWTDYVGGVQAWGYALVSGSGDGAVRLWDMRTGQPHRTLLGHTAPVTCVQFDELNILSGGLDKTVRIWDLRMGNTVDIISFDGPVTSLQFDSRKVVACAGENGVKIWNRTSRQMSTLSINGHTLPATKIRYIDRYMVSGGADGVVKTWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTU2</accession>
    <name>M5FTU2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_82624</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625767.1">
        <property type="nucleotide sequence ID" value="XM_040776580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTU2"/>
    <dbReference type="STRING" id="1858805.M5FTU2"/>
    <dbReference type="GeneID" id="63691642"/>
    <dbReference type="HOGENOM" id="CLU_006714_2_2_1"/>
    <dbReference type="OMA" id="KWPETFG"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000003">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF2">
        <property type="entry name" value="HOMOCITRATE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="9">
        <location>
            <begin position="75"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="10">
        <location>
            <begin position="603"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="811" mass="88284" checksum="1146B3408D4D69CA" modified="2013-05-29" version="1">MLSRAARRRCAQRLSTREKHQRCTFASHVAPPSTVEYNALPQRDCSSITPSYATLMHRLVRARKILGDRPLTLSEKILYSHLHDVERSLAGGGRIRGEKYLLLSPERVAMQDASAQMALLQFMTCGLQRSAVPVSVHCDHLIQARVGASSDLASALDQSKEVFDFLESASRKYGFEFWKPGSGIIHQVVLENYAAPGMLMLGTDSHTPNAGGLGMLAIGVGGADAVDAMTGTPWELKAPLVVGVHLKGKMSGWTTPKDLILHLAGKLTVRGGTGRILEYFGPGVATQSCTGLATIANMGAEVGATTSTFPYTSQMREYLKATGREEVSRFADAAAQHGLLHPDKDAEYDELIEIDLSDLEPHINGPFTPDLATPISKFGELVKEKGWKDEVTAGLIGSCTNSSYEDMTRVASIARQAKEAGLKTKIPFLVTPGSEQIRATIERDGVTESLEDVGALVLANACGPCIGQWKREEHKGEENAILTSFNRNFRGRNDANPKTMNFLASPEIVTAMSFAGQLSFNPMTDTLVDVSGKPFKFYPPVGETLPEVGFAVGNQDYRPSSAPSPQPDAEILISPTSTRLEKLEPFASHFGPSNPRGDELPTMQVLMRVRGKCTTDHISAAGPWLKYKGHLTNIAENTLITAVNDEGGEVNVAIDYEPGQDPVQETIPHVGQRLKARNQPWALVVDDNYGEGSAREHAALQPRFYGCAMIVARSFARIHETNLKKQGVLPLWFVDKDDYSKIGAGDRINTIGLDKIIACDPSAQVTLEVTKRDSGEVLQIPTKHTLSEDQIAWLKAGSALNFIREQKMGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU20</accession>
    <name>M5FU20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625887.1">
        <property type="nucleotide sequence ID" value="XM_040770556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU20"/>
    <dbReference type="STRING" id="1858805.M5FU20"/>
    <dbReference type="GeneID" id="63685618"/>
    <dbReference type="HOGENOM" id="CLU_515813_0_0_1"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="58153" checksum="E0C2DB84AE63DF72" modified="2013-05-29" version="1">MAFVRRELLVWPALDVEFLTTFILSLMSSIDIRAEAGVQLLAEFLDIHEGGHNNAEHFAHEVYSYLRSPYRSLTIYDNIVQYDMPCNNESIPSNVQLPAPPSAHSCLDIRSGQFAARHGRAIGMSPGTSCVQNNRGRYQSRSSDHPSPSSVRDERDNHRHCETSVSSPSSLPTQKKRPRSASEESRGRRALRYRNDLVRRRLNVDGELREPASDFTAATSTQPRHTSSSLCGPIQSTSTEHLSSPFSERRKAPVDNVDDHHKAPTTSHVQLNFESDNFRSPIQERKEVQRGPVKLIRHREPALLSIRSNISASGSLDMHKNGQIPSVEAEGDSFRTEPSTSAARGKESGTALVDTGRKATMQRHGQPDIGLRIKNASKTVGVPPRKLKGVDLGDQVANVEQSETAASDSKANAIHQPSAVLMAQVRARLRLELAMASARETGREPSSTKARCSEHQNYAALSVTEPGAPERRSPEVLKELLLSKLAKEKALLELAPAPVIDQRELAPGADECSRTHIAVEKRLVSSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU22</accession>
    <name>M5FU22_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">DACRYDRAFT_60087</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623599.1">
        <property type="nucleotide sequence ID" value="XM_040775610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU22"/>
    <dbReference type="STRING" id="1858805.M5FU22"/>
    <dbReference type="GeneID" id="63690672"/>
    <dbReference type="HOGENOM" id="CLU_000846_3_0_1"/>
    <dbReference type="OMA" id="MHSFWSW"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090556">
        <property type="term" value="F:phosphatidylserine floppase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000026">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000064">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="20" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="884"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="924"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="967"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1003"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1036"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="23">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="22">
        <location>
            <begin position="151"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="24">
        <location>
            <begin position="853"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="20">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="532"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="596"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="709"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="710"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="711"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="801"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="807"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="827"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="830"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="831"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="831"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EJT96701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1179" mass="133309" checksum="080614D5F8B0A090" modified="2013-05-29" version="1">MPLTAAAAPPAGVEQDGPYIGLEELPPTPKQPKERWAGRGWRWPWEKKVVLEGDRIVRVNDERTNEEVGFEGNYVSTSKYNAMTFLPKFLASEFSKYANLFFLFTACIQQIPGVSPTNRYTTIVPLGLVLLASAFKEMEEDLKRHQQDNDLNSRKAKVLHGTAFRDVAWKAIRVGDIVRLENDEFIPADMLLLSSSEPEGLCYVETSNLDGETNLKIKQAHPKTAHLTSPLAVGSISGTLRSEQPNNSLYTYEGTLSISSTSGELIVPLSPDQLLLRGAQMRNTPWVYGLVVFAGHETKLMRNATAAPIKRTQVERQVNLQIVFLFIVLLVLSIASTVGSSVRTWFFSSTQWYLYLAADAPSRIKEFLQDILTFVILYNNLIPISLIVSMEVVKYWQAQLINSDLDIYYEKTDTPAICRTSSLVEELGQIEFVFSDKTGTLTRNEMEFRQCSIAGVAYSDVVEEHKRGEQGPNGEVEGGQRTFEEMRTRWRNGAGAEVAVIREFLTLLAVCHTVIPEMKGEKLVYQASSPDEAALVAGAEQLGYKFFMRKPRSVFVEIGNKAREFEILNVCEFNSTRKRMSVVVRGPDGKIRLYCKGADTVILERLAADQPYTEPTLIHLEDYATEGLRTLCLAMREIPETEYRTWAAIYEQAAATVNGRGEALDKAAEAIEKDMFFLGATAVEDKLQEGVPDTIHTLQQAGIKVWVLTGDRQETAINIGLSCRLISENMNLVIVNEETANDTKAFIEKRLAAIKTQRSAGEGEELGLVIDGKSLTYALEKEISPVFLELAIMCKAVICCRVSPLQKALVVKLVKKNRKSILLAIGDGANDVAMIQAAHVGVGISGVEGLQAARAADVAIAQFRFLTKLLLVHGAWSYQRLSKLILYSFYKNIVLYMTQFWYSFFSNFSGQIAYESWTLSYYNVIFTLLPPFVMGIFDQFVSARMLIRYPQMYHLGQANAFFSTRNFWEWMGNALYHSIILFGFSVILFWGDLKQATGYDSGHWFWGTTLYLAVLLTVLGKAALVSDLWTKYTLMAIPGSFLFTMIALPIYCLVAPLVNFSVEYRNIVPRLWTDPIFYFTILVLPFICLARDLAWKYYKRTYRPQPYHIAQELQRFNIPDYRPRQEQFQKAIKKVRAVQRMRKSRGFAFSQTENPDRQEQVHLVRAYDTSQQFERPTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUD4</accession>
    <name>M5FUD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_101640</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625987.1">
        <property type="nucleotide sequence ID" value="XM_040767573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUD4"/>
    <dbReference type="STRING" id="1858805.M5FUD4"/>
    <dbReference type="GeneID" id="63682635"/>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="TMAFAYP"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="261"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="471"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="12"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT99089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="658" mass="71258" checksum="F67EAC36CE250805" modified="2013-05-29" version="1">MVKIPKAARAAAAAAAADKPVQKRIKNKEKYLPKGNKERKRKEREALLSEQGKAEGGKAEKEDGLERLDVKDAEESEAARLKREKKEEKKKVKEARRVARAAALPEGEAPPEAPAPAEPETAKESNERKKKRKVPADADADADISAPTTVAPTPVDSSGTPQEERPKKKRKKDRTIDLSATAPTTATVTVSGSTSTTLASTPVPTDPSSISLYLSQNRIHLSSPTPSPLLTFSQLPVHPTLLEHLLSLKFSQPTPIQACAWPALLEGRDVIGIAETGSGKTLAFGVPALQSLVSNTPAGKPSKSKPSIKVLVVAPTRELALQTHDTLSSLSAPFKLLSVPLYGGVPKPPQLQALAQPGAAVVVGTPGRVLDFARTGELDLSGVGYLVLDEADRMLDRGFEPDIREIVGLTKREGRQTAMFSATWPESVRRLAASFQRDPFRITVGAEDLSANKRVAQSVEVLSSSYDKDARLRSLLQSLNHSRQGGKKAEQERTLIFVLYKKEATRVEQSLSRMGYHVAAIHGDMGQQARIAALDEFKQGRVKLLVATDVAARGLDIPAVGTVLNYSFPLTIEDYIHRIGRTGRGGASGKSITFFTGEAHEKALAGELMRVLRDAGCEVPAEMSKFPNTIRKKEHSVYGAFYRDDIPMDAKPKKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUF9</accession>
    <name>M5FUF9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626761.1">
        <property type="nucleotide sequence ID" value="XM_040768860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUF9"/>
    <dbReference type="STRING" id="1858805.M5FUF9"/>
    <dbReference type="GeneID" id="63683922"/>
    <dbReference type="HOGENOM" id="CLU_013364_5_0_1"/>
    <dbReference type="OMA" id="WSTINAS"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47996" checksum="186D0CFEB624C0A7" modified="2013-05-29" version="1">MFSPTVAWRSCPDLTEYDCAYLSVPLDYLNPSPDETVSLALRRLPASAPKDERLGTLFVNPGGPGGSGTAALVNYGQDLNIILKGRYDILSWIPKTKTTPYLGCYPTDFDEWIGAYKEAQLGLPFELGNNSLSWFEKVDAFYLADVASCTNNGNQKMLKASSTAYTARDILSILQAIGEDERGLQYWGFRYGTILGATFAAMFPEYAYRLVLDGVANSNFFTNNPFDSGRSAMDDTNKVWEGFFSECALAGPGRCPLAEPGLTADDIRASIEALIDSLRARPLPVSFSGKFSGIITASDVKTAIFQALYKPTRWADLAKAFSDAKKGDGAALAIFIGEPALTERREPTDNVFRRHMVASGTSRISNAAVMCGDVDPRVAHSIDTPEEFMEYSKELSQLSITGETWTLFAGRCRLWNITAFEAYRGPWTVEDGLQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUJ1</accession>
    <name>M5FUJ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_81513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626806.1">
        <property type="nucleotide sequence ID" value="XM_040776514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUJ1"/>
    <dbReference type="STRING" id="1858805.M5FUJ1"/>
    <dbReference type="GeneID" id="63691576"/>
    <dbReference type="HOGENOM" id="CLU_058463_0_0_1"/>
    <dbReference type="OMA" id="EGNDHFR"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="283" mass="31034" checksum="F6CAEA4AEE10A08D" modified="2013-05-29" version="1">MPRPPSPDESVTSHDTFTSAQEPPSPESEFTDSEARALLDEASKLKELGNEAFRSQKWEEAREKYEQALGCVPMDPLVRRSADEVEHGVPAYEVHPPEEEDEQEVPNPNSGSDNSKGKEKENGTENTSDPPAPEPELKKEARLARAVLNNNIAACLSKQNQPALAIDYCTRALNSDPGYGKALYRRALCRQEVGGWAALSGAKEDLKKLVEILPPSSPLLPSVRSSLLTLEPLLSSTAEKEKAEMFSKLKDLGNSFLGKFGLSTDNFQFSPDGKGGYAMNFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV86</accession>
    <name>M5FV86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_59604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624114.1">
        <property type="nucleotide sequence ID" value="XM_040775572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV86"/>
    <dbReference type="GeneID" id="63690634"/>
    <dbReference type="HOGENOM" id="CLU_174244_1_0_1"/>
    <dbReference type="OrthoDB" id="5407115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="59" mass="6688" checksum="F80E8B2CA1D898CB" modified="2013-05-29" version="1" fragment="single">DTGHKTQDTGHRTQDTGHRTWDMGHRTWDMGNRTWDMGHGTWDTGDGTWDTGDGTQDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW92</accession>
    <name>M5FW92_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_84645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624549.1">
        <property type="nucleotide sequence ID" value="XM_040776691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW92"/>
    <dbReference type="STRING" id="1858805.M5FW92"/>
    <dbReference type="GeneID" id="63691753"/>
    <dbReference type="HOGENOM" id="CLU_115512_0_1_1"/>
    <dbReference type="OMA" id="QWRWDTG"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11813" checksum="D1D3525CC5272373" modified="2013-05-29" version="1">MKVTVKQWHAVAYWRWDTGAPGDQDANADEDAEEDVCGICRVSFEGCCPTCKMPGDDCPLIWGQCTHVFHMHCLLKWLNTASSKQQCPMDRRPWITAERKVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN8</accession>
    <name>M5FWN8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_116076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629260.1">
        <property type="nucleotide sequence ID" value="XM_040770130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN8"/>
    <dbReference type="STRING" id="1858805.M5FWN8"/>
    <dbReference type="GeneID" id="63685192"/>
    <dbReference type="HOGENOM" id="CLU_090092_0_0_1"/>
    <dbReference type="OMA" id="KDLHAPF"/>
    <dbReference type="OrthoDB" id="5377312at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11705">
        <property type="entry name" value="RNA_pol_3_Rpc31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="228" mass="25494" checksum="BDD52AB1E784C0DE" modified="2013-05-29" version="1">MSGRGGGGRGGRGGRGGGRGGFGRGRGSFGGPSLPPGVDFRDIQASMAAPSAQYPPMDIPSMTPLEARESKAVQYQVEIVERMKGGKYWIVEEQSKRNNEIERWFDHLRQKEKIEVKIGLRAEDLNQEFFPASLWDGYFNPTKKQRVVEPKKQKRKRKLDIDALGIDDKDGEGKANDDDLDDDEEEQQDDYDVEDLEGGDDYEANYFDNGEADDDDDGNDDGDRGDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWR1</accession>
    <name>M5FWR1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_81800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627022.1">
        <property type="nucleotide sequence ID" value="XM_040776530.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FWR1"/>
    <dbReference type="GeneID" id="63691592"/>
    <dbReference type="HOGENOM" id="CLU_000604_27_1_1"/>
    <dbReference type="OMA" id="QVTDAWT"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000061">
        <property type="entry name" value="ATP-binding cassette transporter YOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="903"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="946"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1017"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1041"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1130"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="248"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="619"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="908"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1221"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="589"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU00125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1493" mass="165592" checksum="6CB8B5F739E7AE08" modified="2013-05-29" version="1">MSSEKGTIPLSTAPTLEPTHSLDLEKGDQLISPATASASGDTDEKAHRRSSVHTHVGEDAAEGALDKVKQEYLKYDKPYPWYVVFSPARLATRSQLFSYRYQRVPFLSLDVPQPAASLDDAYPSPEQRANIFSQLTYSWVTPMLTLGYARPLEPPDLWKMSETRSSQLLGEKVRVAFERRHKKAEAYNSRLAAGEVSPVFWRRAWWMMRGSNKSGGYAAMEHEWRTVGGKKKASLVLALNEAVWVWFWIGGLAKVLADTSQITSPLVVKALIAYATNSYALHQQGLPTPGVGLGIGYAIILFAMQVIASLGTHMFFYRSTSTGVLLRGALISAIYSRSVHLTNRARATLTNGKLVNHISTDVSRIDFACGFFHVAWAAPIQMIVCLIILLINLGPSALAGFAFFVFATPLQTRAMKELFKMRKKSMVWTDRRAKLLQELLGGMRVIKFFAWEIPFLKRIAEYRAQELRYIRNLLLTRAANNAVAFSLPAFAAVLSFVVYSLAGNQLQPAIIFSSLTLFQLLRLPLMFLPMTLSAIADAQQALSRLYDVFVAETLSSTRETDPNLPVAIDVRDATFTWDAPAPEEGKEGKKGKKQSKRERKAAEKEAAALAIAGGAAAALQEKDTQGKKDRVFQLKDLSFIVPRGQLCAVVGAVGSGKSSLLQGLIGEMRQTSGEVKFGGSVGYCSQTAWIQNATVRNNILFGQPFEEKRYWNAIRDACLEADLEMLPNYDFTEVGERGISLSGGQKQRINIARSIYFGSDIVLLDDPLSALDAHVGKAVFHGAIQGALAGKTRVLVTHALHFLPYVDYIITMVDGVISERGTYQELMGHDGAFARFVREFGSEEERHEQEEEEVIAVEGEKSEDKKKKVAQQGMALMQTEERNTGAVAGSVYGSYLKAGRGRLLIPMLLATLAMMQIGNVMNSYWLVYWQELYWPWMPQGFYMGIYAGWGFFQAISFFLNGTVFAMLTFYASQALHRDAIDRVMHAPMSFFDTTPLGRIMNRFSKDIDTIDNLLGDALRMFCATMSAIIGAVILIGIFEPYFLIAVAVVSVGYYYAALFYRASARELKRLDSILRSSLYAHFSESLSGLATIRAYGEINRFCDDNVKRMDIENRAYWLTVVNQRWLGVRLDFLGTLLTLVVSILAVASRNSISPSQTGVVLSYILMVQQTFGWMVRQLAEVENDMNGVERVVHYAKHVEQEAPQEIPETKPAASWPEAGKIDFNDVVMSYRPGLPPVLKGLAMHVSAGEKIGIVGRTGAGKSSIMVALYRLVEIGGGNIVIDGVDISKIGLADLRSKIAIFPQDPLLFSGTLRTNLDPFGLYDDAKLWDALKRSYLVEETRMVGGDPEKDEDVPSGAQSPVMRFNLDSTIDDEGANLSVGQRSLVSLARALVKDSRVIVLDEATASVDYETDQKIQDTIAREFHDRTMLIIAHRLKTIIGCDRICVMDAGRIAEFDSPANLWEYNGIFRSMAERSSITFDDIVAATKARGRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWW7</accession>
    <name>M5FWW7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_24860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624844.1">
        <property type="nucleotide sequence ID" value="XM_040773887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWW7"/>
    <dbReference type="STRING" id="1858805.M5FWW7"/>
    <dbReference type="GeneID" id="63688949"/>
    <dbReference type="HOGENOM" id="CLU_049109_8_0_1"/>
    <dbReference type="OMA" id="FRVMPIQ"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF50">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YOR292C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="202" mass="23005" checksum="D6EBF164F3D154B8" modified="2013-05-29" version="1">MAAAFRLYNDSFNRNPSRTLMITNGVLTAFADTVAQYAEMLFSKDDNSSTARHYDPFRTLRFFAFGFGMGPLLGRWNMFLEHTFPLRSVGGKISTVSMSSLAKRVICDQIIMAPVGLVIFTGSMGVMEGKTLEQIKKKYKDMYWSALIANWQVWPAAQLINFRYMPLPYRVPFQATLGVFWSLYLSLLNARASKNQNEEVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWY3</accession>
    <name>M5FWY3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629395.1">
        <property type="nucleotide sequence ID" value="XM_040772685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWY3"/>
    <dbReference type="STRING" id="1858805.M5FWY3"/>
    <dbReference type="GeneID" id="63687747"/>
    <dbReference type="HOGENOM" id="CLU_026393_1_0_1"/>
    <dbReference type="OMA" id="YYARDYS"/>
    <dbReference type="OrthoDB" id="3345970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="612" mass="69494" checksum="A68AEE16E9E788E5" modified="2013-05-29" version="1">MVLSDEAEEPLVLPTTSYPPSSPRSKRRPTTNWFTTSRRRIVIYIGGAALVIFILHQAFGRRWTTSDPAWGMPPGPESAYGGPVVAGNQANPTDDCRPALGYPTIQEVTETWPLDRLQHMVDETKGYYARDYSLWLGWNNIRYIIEAGLLQAGLLNRTLIVPSFVYARQCEFGLDVCAAFVEMVNRGDAIGWDEWRQWPIEKQMGWKIPIGMMIDLNHLRETHAVVTMAEYLRLRGLSPDLEKGNGQWSDDTYKLHSRAIPNNRWDPSGVVRVEQQRSPFVLDESNPDSLAAFEARDRVKEKIEEMMQGHSQNVLDWEFVQQAIRSFGLDDDDIKIELFLRAGGFEVLHTYQGARGFDLIKSVVTPIKQVARMSEVHGIIDDFGSWTDEVVHLEGEVHLYRKPGNLRFTSVANLQFFTRTVLYNLRSLPEVSALADRVDQRMKERTDGRMWSAAHVRRGDFVTYGWTENSLEKHIEIVKKKLSRAPSVWNDIRNGQQAHTFDIPDAHLNPAMFEGQIPQNDDPFYIATDERDPAALDYIRSQGGVLIMDLLKPEDRNIVGWPLLITDILALAEQHVMARAAFFNGYAASSVAGGVLNLRAVNGWDPRTTNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWZ3</accession>
    <name>M5FWZ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">LIM-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_117269</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627102.1">
        <property type="nucleotide sequence ID" value="XM_040770348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWZ3"/>
    <dbReference type="STRING" id="1858805.M5FWZ3"/>
    <dbReference type="GeneID" id="63685410"/>
    <dbReference type="HOGENOM" id="CLU_054591_0_0_1"/>
    <dbReference type="OMA" id="ESPKCPR"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09326">
        <property type="entry name" value="LIM_CRP_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000001">
        <property type="entry name" value="Cysteine and glycine-rich protein 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF35">
        <property type="entry name" value="MUSCLE LIM PROTEIN MLP84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="261"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="35827" checksum="66BC73E5393200E0" modified="2013-05-29" version="1">MFGASTLCARCNKPCYAAEQVMGPGRKIYHKRCLTCTECNKRLDSLQLVEHDREPYCKPCHLRLFGTRDLRHNNLTPNGTPDSPPKSTLSPRADLISPRLGTPRFRGVSEEDELDAQITSSPIPRSRAFHPANPLPSIDSAENTPEPIKSAGSRPLPMIPSRTGDPPSPTKMVHPTLTGDLSFRPPSPPISAGLQSPTKPDPAVRPTSPPTTPRRPIPMSPGRTGTSSFPHLPPPASKPLFPSGTGSSTPGSPARFGGVRVECPRCGKAVYFAEQVVAAGKKWHKSCLRCESCSTQLDSTKLTERDGTPFCRACYAKNFGPSGVGYALLGKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX44</accession>
    <name>M5FX44_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627197.1">
        <property type="nucleotide sequence ID" value="XM_040768795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX44"/>
    <dbReference type="GeneID" id="63683857"/>
    <dbReference type="HOGENOM" id="CLU_577490_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="473" mass="51520" checksum="681649D66BC6C8DB" modified="2013-05-29" version="1">MASNLDEVFIPPADDEEMTEALPSIPPPTTLPMAELAPAVLPVPAAVVQTVASAPAPPLSICDTLLPLVVHATNAPSSAPTQGEGSGAPAAVSAAPGPPAPLPWDGAHNDNAASGSYQHRTHQGEHYGSSIDHYGDISPWGSGDEYSRLPTPDFARGSSDTRYCDSCTESWEPYPWLALHPTQNSELAICGREQLADNLVYNCVKLRDVEQELNRLWGEHEEHADEIHNRKRDFESRIARLEDSPSNENLTRSLDENARMSSRMDHAQRLLSNTHDMLLHAQRDAEIQGSHHRDESDALTDEIGRLKKDVSRYRIECDEHRSENDRLKGKLSTFNSAPPPLPPRAPLPSAARKVALPSASHEADDLYDVPMDVGPIEEAPVPASATSAVAKVFTVARVPPVAKVSAIALGKRPTVDKLPSAHPRKMQSLVTATSSSRVHTSRIKNRTHSIIQPLGTYAPQLRPWCQSTVCSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXQ7</accession>
    <name>M5FXQ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629710.1">
        <property type="nucleotide sequence ID" value="XM_040768355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXQ7"/>
    <dbReference type="GeneID" id="63683417"/>
    <dbReference type="HOGENOM" id="CLU_1415118_0_0_1"/>
    <dbReference type="OrthoDB" id="3360807at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="192" mass="20523" checksum="B8BE4F8F9E1E9643" modified="2013-05-29" version="1">MSVIFTGIIGCQSWHPSVAGSHSWTCTAAILLPAHAAVPLMITEEELQGVLCYFPPPGAAVPPEEGVYFASAKMASATPALVMGEDIQGLEVEYELDTLVLLPQAFKQFEVALTITVIGCPCNIVNQMFDLKAQPYIFNGKQVACFGCYFSEEGHFARKVPTINQTALLSITGLLMGTALPQEGSPEGQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXW2</accession>
    <name>M5FXW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628251.1">
        <property type="nucleotide sequence ID" value="XM_040772840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXW2"/>
    <dbReference type="GeneID" id="63687902"/>
    <dbReference type="HOGENOM" id="CLU_2372759_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="95" mass="9743" checksum="5DE1BC15EE3FC06D" modified="2013-05-29" version="1">MASLSPRSARSLSLSVLSPLSAPARSARSLSLSRSQSRAFSRSQSLSLSLSRRLSLSRSHSLPPALPSHTFPAPAPNGLPSPPSAGAQSGVRPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXZ5</accession>
    <name>M5FXZ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_31180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629820.1">
        <property type="nucleotide sequence ID" value="XM_040774345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXZ5"/>
    <dbReference type="STRING" id="1858805.M5FXZ5"/>
    <dbReference type="GeneID" id="63689407"/>
    <dbReference type="HOGENOM" id="CLU_021768_3_3_1"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="117" mass="13462" checksum="919646234AC43F38" modified="2013-05-29" version="1" fragment="single">DERQRHVVEQLRVVVQKLRRIPTPHSNAICSAAGGPVIDERLDLWRECGPFENEPDMRRCLRYPGPGQGAVIKAPDVKIRFTHGDFAPKNIMVDPRTGAIIAIVDWEQSEWFPDYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY05</accession>
    <name>M5FY05_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625334.1">
        <property type="nucleotide sequence ID" value="XM_040773698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY05"/>
    <dbReference type="STRING" id="1858805.M5FY05"/>
    <dbReference type="GeneID" id="63688760"/>
    <dbReference type="HOGENOM" id="CLU_083413_1_0_1"/>
    <dbReference type="OMA" id="VWLSILW"/>
    <dbReference type="OrthoDB" id="3364107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19035" checksum="468D6D345B3335D0" modified="2013-05-29" version="1">MFSLLRLVGLGIVAFLSIIVLGISANVNFGLGIATAVLTIISVIPVLAIDFFRKGVFTSWTSVELGLVGLLWVLWLATGADAASLASAGCDAFCEGFFCYGYSASTCSQVRAIAAFGFIGFFILLALWVWTLVIGVRAHNVGDTRIWMTPAYEYSPGPKMYPGGAQMTSTMPNYNPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY58</accession>
    <name>M5FY58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_99426</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629890.1">
        <property type="nucleotide sequence ID" value="XM_040777589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY58"/>
    <dbReference type="STRING" id="1858805.M5FY58"/>
    <dbReference type="GeneID" id="63692651"/>
    <dbReference type="HOGENOM" id="CLU_370053_0_0_1"/>
    <dbReference type="OMA" id="ACINLPF"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DBL_dom_sf"/>
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        <property type="entry name" value="DH_dom"/>
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    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF270">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DH" evidence="10">
        <location>
            <begin position="165"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="11">
        <location>
            <begin position="559"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="93"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="666"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU02996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="752" mass="83074" checksum="516F4D44E77E8640" modified="2013-05-29" version="1">MSRTEPSSDSSAQGILFPRSHLRTSSYPSSNNGDGDQGTDGAEGAERTEDRLATLRPPALKAPISFRRLSTTSAGSGHRSAVSSVVSFEEVALQSPPLDPGSAGTSPSPRSALRPLSEQARSSSFSGFGPLSPALPRSPRKYGKSRRDSRQRGSMDEGYQRRALKRLKVVKELLDTERSYHFLIPLMESLETKRPLVTRDDLTAIFSNFVDIWNLHRALLLGLTEAVSPPPSQAVSPPLSSVMRAHLPYLSMYKLFVANFPSSMSTVSHLQSTSPPFRSWLAEREKDPRCRAMGLVAWLLTCVQRVPRYLLLLKDLVTYSDPHEEETEQLRRVFVMVSKTAETLDRALAEHSLTLSALALQRACINLPFPLISPGRKLIKRRPLLRESPKALEPRECLLFTDCILLFAPLSEEGWLSGSRPGLQRRRSKSGNDAQIRRSGEEEMRESERWRWVGKLEIKDVTVVGARCAGEGVRKFELLSPKESFAVYAASAAECQAWIDAIRETKSLYLSSIQTFSRPLDTLTSSTSTRHLRLSLQALPAEPERKKVEHFVPAVWVPDRKATACMRCGKPWTVLRRRHHCRLCGSVVCSRCSTKTFFIVHPGAPGPSENKPTRACNTCYENVFPLIAERSDECPDGLPHAALDHRLSTVTLSSTTSVLRSDGDYHGSDSASGFGHPGPELDNGLPELTPTLLELGVSPFAGALKRTEVQRLEVTARLSLVETGNGEAANRFHTIGGRAVKRLSVLLGKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYD9</accession>
    <name>M5FYD9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PDZ GRASP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24192</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625464.1">
        <property type="nucleotide sequence ID" value="XM_040773590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYD9"/>
    <dbReference type="STRING" id="1858805.M5FYD9"/>
    <dbReference type="GeneID" id="63688652"/>
    <dbReference type="HOGENOM" id="CLU_025095_2_0_1"/>
    <dbReference type="OMA" id="FERAGEN"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="7">
        <location>
            <begin position="125"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="224"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR607583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="29393" checksum="BAA399D096E89A51" modified="2013-05-29" version="1">MGAGQSSSSQLPTALHVLRVSPGSPAALAHIEPFFDYIVGLVGAGVSDQSLEPDNLGRIVDQYEGRTLSLRVYSAKTKSSRLVSLTPSRVWALAQTSDGFDDPNAQPSLLGLSLRLCDPTHALENVWHILEVMEGSPAESAGLVPYGDWIVGWSGGVLGAESDFYDLVEAHVEKPLRVYVYSYDFDSMREVVLIPNRQWGGEGLLGCGVGYGLLHRIPQVEPHVDASSAGPTTFPAPQSRPSTTIYEEDERGDDTFVPGEVPWSPSSQVRATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYM0</accession>
    <name>M5FYM0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625539.1">
        <property type="nucleotide sequence ID" value="XM_040769075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYM0"/>
    <dbReference type="STRING" id="1858805.M5FYM0"/>
    <dbReference type="GeneID" id="63684137"/>
    <dbReference type="HOGENOM" id="CLU_1315380_0_0_1"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="188"/>
        </location>
    </feature>
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            <begin position="1"/>
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    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="209" mass="23165" checksum="6B511F88ED35ED82" modified="2013-05-29" version="1">MKHSNDRDSIRSLDGSEDGHARQALEKLSQELPQEQTLGDEEEEELLRCSVCGYKYSCATCILYGVAARWAASTSTSSGLSTVPGLSPSPSDISASSSSPLPAARLLRHVRPCSAPPASSKPPGPDLDDVCSVYCVICDTFYSYPVHNPPRQVTERCTHFERACEDCIQTWLETLIERPGHMHCPIVRCAEVLRYEDVKYWAGAETWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYU4</accession>
    <name>M5FYU4_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYU4"/>
    <dbReference type="STRING" id="1858805.M5FYU4"/>
    <dbReference type="GeneID" id="63683319"/>
    <dbReference type="HOGENOM" id="CLU_688912_0_0_1"/>
    <dbReference type="OrthoDB" id="43122at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="400" mass="42937" checksum="8B96A46BF4D6F062" modified="2013-05-29" version="1">MPSIINTSRPLFAGAAQNAAPYSRSTTPSGSSHYKTPAETAENGDDDDIPLADRIPTALAAQKSIRVSARSSARRPPKLKSSVVALPSQIEVEGGKPPPSPGLPAEELMQKLMDLQVQHSLPASKNDASPPVKRLTAREPAGSAYTSIVLRPVATTIPSREQSRPAVLQRSEDKRKGPITSPTISEFQSSIAPGSRHAVMTQGAPAPIVALPRSSEMPSRVVSRNGTMRQQQSRPSDEAQITQSESRADSDTNTRSLSRSNTKKSHIDPQSKSCAFSSAGFSDNHVAGPPQAYFGPPQLDILFTVDVHVLNLRTVVKIDVDASTTAKSALDIVMKQSRATTRDIPAQQDVTLWELVNDFGMGESLPVFCRIGPETMAQNDLYENSSISGRCVRHGTCNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYU5</accession>
    <name>M5FYU5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ER to Golgi transport-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24307</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT98731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYU5"/>
    <dbReference type="STRING" id="1858805.M5FYU5"/>
    <dbReference type="GeneID" id="63688696"/>
    <dbReference type="HOGENOM" id="CLU_034705_1_0_1"/>
    <dbReference type="OMA" id="QRHEGCR"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="8">
        <location>
            <begin position="146"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="50765" checksum="E83EA6F6613D760B" modified="2013-05-29" version="1">MAKGGVFSQLKGLDAFGKTMEDVKVKTRTGALLTLISACIIVFFTLMEFVDYRRIHLATSVVVDRSRGEKLLVNMNITFPRVPCYLLSLDVMDISGERQHDVTHNMQRVRLSPQGIPIPDVLPESGLSNEIEKVIEAREGGECGSCYGGDPPASGCCNTCEDVREAYMRRGWSFSSPEDIKQCVNEGWTEKVKSQSEEGCNISGRVRVNKVIGNFHFSPGKSFQTNAMHVHDLVPYLKDANRHDFGHEIHYFGFESDGEQQAEVGRLSKSIKTKLGIDKNPLDGLRAHVRSLSRRETRRVPGMSSNRRSYRPEQTEKSNYMFQYFLKVVSTKYEMLRGTVVNSHQYSVTSYERDLSQGDKAQRDEHGTMTSHGVSGIPGAFFNFEISPMVVVHQETRQSFAHFLTSTCAIVGGVLTVAAIFDSMLFSAERKLKKSSNSTYTNGSGLNGGAYQKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ02</accession>
    <name>M5FZ02_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625704.1">
        <property type="nucleotide sequence ID" value="XM_040771319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ02"/>
    <dbReference type="GeneID" id="63686381"/>
    <dbReference type="HOGENOM" id="CLU_1124492_0_0_1"/>
    <dbReference type="OMA" id="GMCALNI"/>
    <dbReference type="OrthoDB" id="2326446at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="69"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="247" mass="27627" checksum="5CA0BC1A36F48E32" modified="2013-05-29" version="1">MPHALPLAAHASDSSPQGPCTYNSFRVPFYVVITNHFKDIDPVYSISARWSKNVTHLKTASGLGFTLCPFLVPAPPAAVEELRKMRIACGWDVELIDEWIIEIKEGRRIQWTAFKDDTAIGMCALNIYSIHDESLANGVDRGEVAGMFLYPEWRSLGIGKTMMTYVEHEAAQMGMKITTVNTRSMGPSLGPYLRRGYREYKGREMKYLLETILGLGLTPEHMSAAFLEKPVPAASTVFFKMDVQTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ44</accession>
    <name>M5FZ44_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628676.1">
        <property type="nucleotide sequence ID" value="XM_040772715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ44"/>
    <dbReference type="STRING" id="1858805.M5FZ44"/>
    <dbReference type="GeneID" id="63687777"/>
    <dbReference type="HOGENOM" id="CLU_052717_0_0_1"/>
    <dbReference type="OMA" id="VEMTKHK"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005371">
        <property type="term" value="F:tricarboxylate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000053">
        <property type="entry name" value="Mitochondrial DNA replication protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000085">
        <property type="entry name" value="Tricarboxylate carrier, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="210"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="32187" checksum="9DA12028C62513CE" modified="2013-05-29" version="1">MAPTREPGQKGINWSNIAVGAIMNMFEVTTLGQPLEVLKTQMAANRSQSMLQGVGTIWSRGGFLGFYQGLIPWAWIEASTKGAVLLFTAAEIENRSIAAGLAPGWAGLLGGMGGGIAQAYATMGFCTCMKTVEITRHKQAASGIKPPSTFAVFMDIYRREGIAGINKGVNAVAVRQCTNWGSRMGFARLAEDTIRSMRGKKEGEKLAPMDKILSSSIGGALATWNQPIEVVRVEMQSMSKKPGTEKLGVFGTLMYVYRENGIKGLYRGVTPRIGLGIWQTICMVSFADYVKAWVNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G072</accession>
    <name>M5G072_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_23813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626099.1">
        <property type="nucleotide sequence ID" value="XM_040773406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G072"/>
    <dbReference type="STRING" id="1858805.M5G072"/>
    <dbReference type="GeneID" id="63688468"/>
    <dbReference type="HOGENOM" id="CLU_080773_1_1_1"/>
    <dbReference type="OMA" id="CIFAKND"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="171" mass="20150" checksum="DEF3E885C14EA3DF" modified="2013-05-29" version="1">MPIINEYQVLGRHLPTDADPTPRLFRMRIFAPNDVVAKSRFWYFLRKLKKVKKANGEIVAVNAISERKPLKVKNFGIWLRYDSRSGTHNMYKEFRALSRAEAVASMYQDMAARHRARFRSVHILRVQEIEKTADVKRPYIRQLLEPGLRFPLPHRVTKSRSKFVAVRPKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0A3</accession>
    <name>M5G0A3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626149.1">
        <property type="nucleotide sequence ID" value="XM_040767552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0A3"/>
    <dbReference type="GeneID" id="63682614"/>
    <dbReference type="HOGENOM" id="CLU_533180_0_0_1"/>
    <dbReference type="OMA" id="VMKMLVQ"/>
    <dbReference type="OrthoDB" id="10636487at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="288"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="511" mass="54388" checksum="2FC3D79B0F47847C" modified="2013-05-29" version="1">MPHHNPHRQESGFDEEQLEQASRESVQDAYAPPLNVSSYDEQAQIRRAEQESLQDAYTTGYSRPQEFVSVGREGYQRPPEEYAGYGRDEYQGPPQGYGRGEGYGRPSEEREYGRRPPQSDNQMHYHAPPGRPPQETQFDNARYSAPPRPDDEYGRSQMPQQQEQEHHHRHHHQQQQQMGEYAGDGESYGGGEYRPPVNAPHVEEYERPRPPAGEGYGNGPERPHNVQHAPTGPISQHHGTAAEYYNNEPPQPRPQQETYHDAQDGQFSADVASVHPPKPHDGPSPPNLQNAANFASQHWQDGVQDQELFNAAAAQVAAQQGHSQPSDDDPPTPTIHPHAVNSSSTPTQMGQAAAMGALQHVMSGAGGGAGGSLTSLLGGLTGGGGVGAAISSLLGASGGGAPSAPQAGAPHPQGASTGPAQGGAPPAGSPAAPASPYEKLIAVAMMKASELFDKHGSGDPAAKQQGEPIQAAASTVMKLMTRYQSGGSGTGGQFQPGEIQGLFGSFMKAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0I0</accession>
    <name>M5G0I0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Alpha-aminoadipate reductase</fullName>
            <ecNumber evidence="6">1.2.1.31</ecNumber>
            <ecNumber evidence="5">1.2.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">L-aminoadipate-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_96134</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = L-2-aminoadipate + ATP + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46936"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.2.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12308"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(S)-2-amino-6-oxohexanoate + NADP(+) + H2O = L-2-aminoadipate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12304"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.31" evidence="6"/>
    <dbReference type="EC" id="1.2.1.95" evidence="5"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626234.1">
        <property type="nucleotide sequence ID" value="XM_040777349.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G0I0"/>
    <dbReference type="GeneID" id="63692411"/>
    <dbReference type="HOGENOM" id="CLU_000022_19_0_1"/>
    <dbReference type="OMA" id="ENDKFTM"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004043">
        <property type="term" value="F:L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014397">
        <property type="entry name" value="Lys2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03443">
        <property type="entry name" value="alpha_am_amid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF1">
        <property type="entry name" value="L-2-AMINOADIPATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001617">
        <property type="entry name" value="Alpha-AR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="18">
        <location>
            <begin position="869"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJT99336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1408" mass="153854" checksum="BE562FBD089C55FE" modified="2013-05-29" version="1">MSTRIQQATARLQSLPSIALPTDYPRPSPLRLVEAVQSHDLPLTTSRALLKLALFQEGDEGDVAVSPETQEQPTPFQLLLAAFVLLLHRYTGDTDLLIGSKAPSTPDPLILRISVEPNDPFWSVVRRVQSTERDAEACAVPYEDLLAALRLPSVTPDSPASVFRVRFFDGTDRPPDGFLQSTTLTTDLTLYVTRSAAADSARASLLPQLSLSVAYNSLLFTSARIAHLTAQLSQILVAAASDPLAPVSSISLLTVEQSKVLPDPRADLNWCGWAGAITDIFSRNAASHPEKTCVVQCLPLQGGVQQRVAYTYDQIWRASNILAHCLVQGGVQQEEVVMVYAYRSVELVVAVIAVLKAGATFSVIDPAYPPARQIIYLKVAKPRGLVVLSGAGQIAPQVREYITTELDIRVEVPAVSLTPSTVLGGPGPNSQDILAPFAPRSGENPAITLGPDSIGTLSFTSGSTGVPKGVRGRHFSLTHFFPWMATRFNLSSSSRYTMLSGIAHDPIQRDIFTPLFLGAELWVPTSEDIGTPGRLAEWMRDAGVTVTHLTPAMGQLLSAQASAQIPHLRNAFFVGDILTKKDCLRLQGLAPNVRIVNMYGTTETQRAVSYYEIPARAEHPAALQEMKETIPAGQGMVDVQLLVVNRHNREIKCAVGEVGELYVRSGGLAEGYLDQESTSTKFVQNWFAQGLMFGDSIDGPARRYWKGVRDRMYRTGDLGRYLPSGLVECTGRADDQVKIRGFRIELGEIDTCLAQHPGVRENVTLVRRDKNEEKVLVSYFVPMEGIDEWESEVDAKDEEGAVSFSRRYRRLIRDIREHLRKKLPSYSIPSLFVPLSRMPLNPNGKIDKPALPFPDTAAAAAAASTAAPTDMTPTQKTIHDIWARLLPTPSLPISLEENFFDLGGHSILATRLIFELRKTYAIDVPLGLVFDSPTIAGLAEEVDLLRQVDFGLAKDTAPEVKVPVSGKKPVPAPADEYSKDFDALLPKLKPSYAPLPPDFATKKLTVFLTGATGFLGAFILADLLARPERVAKVICLVRAKDEAAALARLREGSIGRDVWDEKWVTDGRLQVVKGDLAEERFGLSVQVWDSIATQADAVLHNGALVHWVFPYSKLRAANVLSTLTALELASTHKSKALSLVSSTSDIDTEHYVRLSDSLSDGDRTGVPESDDIEGARTGLKTGYGQSKWVAEKLLMEAGKRGLRGHIVRPGYVVGHSTSAVTNTDDFVWRLVKGCIQLGLVPDIHNTINMVPVDHVARITALSAIDVPTNTFPVLHVAAQPAVRFNDLLLGLYHYGYKVQQIEYLVWRRKLEEHVLEVQDNALFPLLHFVVDDLPTSTKAPELSDSNTVALLTRNNSPDSMTVDEALLGKYLAWLVATGFLENPTESGKPLPKLNLPNGQVKAIGRSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G161</accession>
    <name>M5G161_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626459.1">
        <property type="nucleotide sequence ID" value="XM_040768920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G161"/>
    <dbReference type="GeneID" id="63683982"/>
    <dbReference type="HOGENOM" id="CLU_1045932_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="266" mass="29121" checksum="E7DA8EB0345972F5" modified="2013-05-29" version="1">MAAPSTEYIPGEEAVSKNMAMQHPKCHGGHPQGLKERGKWLQEAEKVGKMQAAMTKLLLDKPHALQLLNQGQVMFLGPHTQMLWEFLAEDMGMMKAHHLSAPISVENKDLPLDAWVEDNNDVGPIPPAIAALNEEDTKDGGVLPGDSQETDQLASNLQKQVVLVAKPLISGMLPWGSILAAVLAPTGIEQPHLQWALQTLMMQDNAPQQQVLTPPDIQHGNYYDFPGNGTPQIFGMMTVGFPHNGIDPHGYLACQCLPRRGIQRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1H9</accession>
    <name>M5G1H9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630975.1">
        <property type="nucleotide sequence ID" value="XM_040768046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1H9"/>
    <dbReference type="STRING" id="1858805.M5G1H9"/>
    <dbReference type="GeneID" id="63683108"/>
    <dbReference type="HOGENOM" id="CLU_885639_0_0_1"/>
    <dbReference type="OMA" id="WVRTYDP"/>
    <dbReference type="OrthoDB" id="2367685at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="34278" checksum="E17B724298B6D585" modified="2013-05-29" version="1">MANNTNPPPDYTYAMNQVDVPPGQSGQNNQLLQPGSPNPALTARRSMEDEMRELPEGWVRQWDPAQNHHFYVDTRATPPRSIWVHPYDDPEYLSTLPDAHPAKVWHNTQQQQHTTTTAGGASGPAGTSGSAPHARKHGVFTKLHDKLTGTTKEERDAEKERQRQARLAHEQEMQRRYAERQQQIAQQGYPAGYAPGGFAPPGGMYARQRYGYGGYPGYGYGPGGFGRTGGMGGMGMGLPLFGGLAGGLLLGDMLGDAGDGGGWGDGGDGGRWGDGGDGGDGGGWGDGGDGGGDGGGWGDGGDGGGDGGGDFGGGDGGGDGGGDGGGGGDFGGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1K3</accession>
    <name>M5G1K3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626614.1">
        <property type="nucleotide sequence ID" value="XM_040768949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1K3"/>
    <dbReference type="GeneID" id="63684011"/>
    <dbReference type="HOGENOM" id="CLU_946722_0_0_1"/>
    <dbReference type="OrthoDB" id="3413943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="32585" checksum="A78597E06151B0F4" modified="2013-05-29" version="1">MATPATILLPFDVWHNIVLLIEDQADLIQLCLINSNIGAIATKCLYRAVNLSSLLNIVHFYRAVVKHPFLASQTVALSLRLGNHDFQGKVSEYDTCSPDQVSQAARPSAYLRLMFRLIHVLVGLKTLHLATPHSFSQPRIPISFSVNLGRIKRPLSSFTFHAHGQPSVLPILLTQTSLEELCLHGMENVLEELRILPPNCLPRLRFLESDVSMASVLARDRPIQAFSIVGSLTSVEPARLSSCLDHLQMSTGPIQRIDLSLKKTDCNIFSDISTALPDIVALCLDIWLPLVSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1K6</accession>
    <name>M5G1K6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629498.1">
        <property type="nucleotide sequence ID" value="XM_040771093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1K6"/>
    <dbReference type="GeneID" id="63686155"/>
    <dbReference type="HOGENOM" id="CLU_2183851_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="12731" checksum="2DD0D5EB357AE6FC" modified="2013-05-29" version="1">MPPFITEYPYFPGLSKRIITKATLFELNAQAAKFPYGHSPKEKTQASYLERTKMHHLEYQHQQSKKVQEKQNTKKAKSLACLGKWKMQKWKMQKALCEVVEALTEDQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1V7</accession>
    <name>M5G1V7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626779.1">
        <property type="nucleotide sequence ID" value="XM_040770398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1V7"/>
    <dbReference type="STRING" id="1858805.M5G1V7"/>
    <dbReference type="GeneID" id="63685460"/>
    <dbReference type="HOGENOM" id="CLU_549833_0_0_1"/>
    <dbReference type="OrthoDB" id="2333993at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="54947" checksum="FDE42ED82F8E3213" modified="2013-05-29" version="1">MPYNVEAALAHQYYHSGYLPYQTEHATGLSSTQRPHSGPSSAPDPATFDFPSGTTKYDCPWCDKSYTGPNGRSIWRRHAQEKHNLPCNSRRSRWDADPDRPRNSEDKKDRNLACKRQWAKDNRIKKRLLKQLDTFSPSNLRRTKIEADLTQCTKRLRSKSVEKENLEPPLFQAPYSQRTPVFAQMDSNAAASDVYDYASDPSVSGWSTASQESTLLDGWDGFNSALSEAPSPDTVTRDDPVSMLVSYTTAAAAEARRSPPSPVHSVAPRDDEVYSEEEAEEMMQFVEQYSIADSDSDGDPPPPGAVEQFPPPSNFEHANGASYSLSLDAPGDSSNVSEMSGLIHDNYSCTHVTAVAPFSLAIRRAIWKREQEEAEEESKIEESLFTPANDSESDDYAFGDRTYEQEGQFSPLHPVSSTSFQVNSDRRSISGPAATPGLGKCSKMTESPFHIKPVETTPDKRRLAWELGLGADSSPGSGFYLAQVKSAVAGRWVDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G294</accession>
    <name>M5G294_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631215.1">
        <property type="nucleotide sequence ID" value="XM_040772125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G294"/>
    <dbReference type="GeneID" id="63687187"/>
    <dbReference type="HOGENOM" id="CLU_1129024_0_0_1"/>
    <dbReference type="OrthoDB" id="2903405at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="27340" checksum="9B063F4F388C743B" modified="2013-05-29" version="1">MDNTHFIGFPNSPHHTRARGVASAAAHGSGAVTPPRTPVAQRTRPRSGVLHTPGGWPAQEEDDFHTSQESPIPPPANLDWPAARPSTPFRPEIQQPNNAHTPRTPSRVAVSELPRTPANMSTRSNAAPATPSYLTPVTNEQLKFLTSLPHDFRMSYSNELTSLAEHLKRQDRLHRAGEKTVDFRERKIEELKAELESCKRQLADLEALRQDPDLSDLQGLARRSAKHEAQIAELQEQVAALQGHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2A7</accession>
    <name>M5G2A7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PIN domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_79148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629244.1">
        <property type="nucleotide sequence ID" value="XM_040776379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2A7"/>
    <dbReference type="STRING" id="1858805.M5G2A7"/>
    <dbReference type="GeneID" id="63691441"/>
    <dbReference type="HOGENOM" id="CLU_021984_0_0_1"/>
    <dbReference type="OMA" id="PFLQKTC"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09897">
        <property type="entry name" value="H3TH_FEN1-XPG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="7">
        <location>
            <begin position="425"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="636" mass="70277" checksum="4F1358DEE47A3204" modified="2013-05-29" version="1">MGVLGFTPFLQKACPDVIKHFPTRLRALSGKKIAVDGNLVTQRLHFGAGSHEHGHIIGWYKMIKDMHANGVGVITVWDGKERSSAKAREQARRQATRLLQLARGAHEQGRLHRLQRLTGAVKKYQHLCRAEQLQVSAAVRLAVGAAAVAQLHGLADVMEKVHSSKSIKLANEIVNDTELDYAEADRALQKEMLLHLYSHEEREALASFLDHVDPEDVTTVAAVDTAYESVLEALANASEADERPADAKWFDMSADDMGAYRFGGREKDPKPEVIPEPHTTLGLSSSYPAPITSLQYPGFSPDTITKELTELYQDFRETTLKNSPELSTSLPEVMPTLPLAVIEPEHVLPSKYQAQLTADEQLFWKRLIVEVAEGSVEGVPKSDDVADVALLENLFNRSGQMALSYEKRNRQPTAATYAESRRILSAMGVPCIEAEYPYEAEALAASLVINGLANYVGSEDTDVLIYEAPLLRNLTNRQLPLALISGTDVRNALQLSRESFVDFALLLGTDFTQRVKNLGPHTAIKLIRTYGSIEQLLRSQTKYVPSSPGVYMEQIEVARLVFSTLPPVPDSAPFQEGIYDEQEVQALLKEYHVQVADLAEDMGDHTAHDGHLGANYFGDNPVDPSGTYWSYGTIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2B5</accession>
    <name>M5G2B5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631240.1">
        <property type="nucleotide sequence ID" value="XM_040769861.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G2B5"/>
    <dbReference type="GeneID" id="63684923"/>
    <dbReference type="HOGENOM" id="CLU_260509_0_0_1"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06595">
        <property type="entry name" value="GH31_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19178">
        <property type="entry name" value="SET_SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044430">
        <property type="entry name" value="SETD6_SET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF89">
        <property type="entry name" value="ALPHA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="831"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1266"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1033"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1313" mass="148087" checksum="60248F6FC4DA55E1" modified="2013-05-29" version="1">MEQYKLRDLSPVADPAAVVQGDHWRFTILTEGVLRYEYAPDGVFEDRASTFAVRRKLPVPKFRVIGKGENSDLEILSSRFHLVYDKLPFSSSGLAVYVRGANLNRHSFWRYGVEPRASMTLFGTARTLDLVDGRCELGPGVCSRDGWAVIDDSKSMLFEPDGWVSGRKEGERVDGYVFAYGTDYKEAVKALYAISGDTPLLPRWALGNWWSRYYPYSAEQYLSLMDKFKSEGIPLSVGVIDMDWHLVKHPRVTHAGWTGYTWDPDLFPDPDAFLKKLHDRNIKVTLNIHPHEGIHAFEDAYEAVAKALGRDPSTGDPIPFDIVNKDFLNVYFSVLHRQLEKQGVDFWWIDWQSGEHTKIPGVDPLWMLNHFHFLDSGRDGQRPFTFSRYAGPGSHRYPIGFSGDTHISWASLEFQPEFTLTASNIGYGWWSHDIGGHLRGTKDDELTARWVQLGVWSPILRLHSTHNLFMTKEPWAYGIEARTVMEEQLRFRHRLMPYLHSMNYRAAKEQEPLVQPTYWKYPTRDEAYRNRNQFFFGSELVVAPITTPRDKATRYGAVRTFIPEGRHIDIFTGTVYDGNRELVLYRPLERYPVLARKGAIIPLDAAIVPENGCILPSSFEVMIVVGADGQFDIMEDDGKGSNLDAVKWAKTSITYSQEKGIIRIAPVTVANVSGLPATRNWKFHLLGVSPLKNIKATVGGSVREISIEAVATGSVVQVGDVAVDTEIVLELGRKPQLDVLDPALRVWKVLDEAQIKFEDKIAAWKVMQSSGSRLAKAGGLSALGLENTVLQACLEQLLADSRESFNIKGAKTKRMDFLNWFTSAGGTFDSSAIGIEDLPETGRGAVALRDIYEGEKLFTIPRSLLLSTRTSSLPFLLGEEDWNALGDGWAGLILCMMWEEARAEESPWRGYLESMPTEFSTLMFWTDEELGLLKGSLVLDKIGRAGAEKDYNEKVLPLLQKRTDLFAPSLFQTRYTLQNYHIQGSRILSRSFTVSPWSGAVPENDEDEAPELVDTSMASAGDELMGEVNVLGDDSEGNIDMGDMDEDEEDEEREKTEDVAMVPMADMLNARCGCNNAKLFYTRDDLQMMATKPIAKGEQIWNTYGDPPNSDLLRRYGYVDALTLPDGVGSPSDVVEINADTVVEAAKVQSYQDRIDWWLEEGGDDAFVLDVTYSVPDEMLSLVRLLLLNQEDWEKAQSKGKPPKPKLDEKSYEVLLVVLQKRLAMYPISLTEQEGMLRSSNELNEKRRNALIVTTGEQRILHKTLEKLESLNQRSSGTNGDGRKRKGDKEESQRGTKKARRTHFIIDKKLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2R7</accession>
    <name>M5G2R7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629409.1">
        <property type="nucleotide sequence ID" value="XM_040768300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2R7"/>
    <dbReference type="GeneID" id="63683362"/>
    <dbReference type="HOGENOM" id="CLU_525815_0_0_1"/>
    <dbReference type="OMA" id="DFRDPAW"/>
    <dbReference type="OrthoDB" id="3352270at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="518" mass="58826" checksum="5C2E619904A2A8FC" modified="2013-05-29" version="1">MSSASREISQRNALPSSRLLEILNYRNRTSPVHAPYGQGRSVLALTQHLSPRTFTTEATPGQEAILLHDALWELNRQIEAVTIVRETMLREVQLLQQTLAAHRSAFRRIPNEILLHIFSYVVDQPPDPFAPSTLCCVCREWHKLVLNARELWTRITFELPNRRSRSDPYFDMISTARAYLTRSDPLPVSVYIVSQLQQPNADEVALPLSILSNNFGRCAKLYVFYDTLEPMYATLDALTRFPPATLLDTLSLTVGHHKPERLEYIAVDRRTEPYAFFSGHAPKLKHVELNGIAVPWQGPAAALTGLEELRLAKQPREERPSLQEFLQLLKASPNLERLWIFRSGPRWGDGECEDVQLCQLTVLRLVDVAPEITECVMPYIAMPCLEALQLSFYDHRSGQRLNSSAVLKTLSGTKNWLLKSLRLENAMFRTTALVSFLIERGKDLREIYLYSTSADDQLLDILTPSANTVCPQLMSLTLERCDDVSDCGLRIFWKQRKEGGVLQRLHVVNCGGLNLTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G355</accession>
    <name>M5G355_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_95592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627189.1">
        <property type="nucleotide sequence ID" value="XM_040777306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G355"/>
    <dbReference type="GeneID" id="63692368"/>
    <dbReference type="HOGENOM" id="CLU_1959513_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="128" mass="15080" checksum="E95CE51E05246F7F" modified="2013-05-29" version="1">MLASRALQEFSQVYWNENVEDPQKQDITLFPLSAESKFRHLTEEIIYDLMAAVPLWDFSLWPSGQSQRERQTRRLLLRCRRCKWRPSTSLSPRPHLRLPRISLLHRPTLAELRRVIPKASTSVALQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D6</accession>
    <name>M5G3D6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631620.1">
        <property type="nucleotide sequence ID" value="XM_040771910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D6"/>
    <dbReference type="GeneID" id="63686972"/>
    <dbReference type="HOGENOM" id="CLU_2687779_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="7786" checksum="046B21BB40132F65" modified="2013-05-29" version="1">MATAHKNGMSSALALPPTQGSPSKCGVEGMGNPLSECRQGGAPICDYFIHGDNKDAYWSGGRFKSDFFCVVQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3I8</accession>
    <name>M5G3I8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_114114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631685.1">
        <property type="nucleotide sequence ID" value="XM_040769765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3I8"/>
    <dbReference type="STRING" id="1858805.M5G3I8"/>
    <dbReference type="GeneID" id="63684827"/>
    <dbReference type="HOGENOM" id="CLU_052397_0_2_1"/>
    <dbReference type="OMA" id="PMSIVRA"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="29"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="294" mass="32434" checksum="AF31039F5F92A925" modified="2013-05-29" version="1">MTSSPVHGRSRSRPSSSPSIPTLFQQPTADIILLSSDRPAAELRVHRRILIEASEFFREMFTLPQPVRQDGSPEEEEIPKIDLQEPASVLIPLLTLLYPVPPPSFSSLDLLPALFRSAQKYDLPSLPPLLACVLREPRFLQAEPLQVYALACQFGLKEEARLASRATLRVDLMALLLPLPDKLGSMLAVDLVQLVALRVQRASQAKTLLKAPGALQGLRCISCGTLPSWVGEWRRRACVELDRYPVSETIFASSFLGEVIGMCGIGCGKCGIAKWESGEWERLRAEVDALPNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4U8</accession>
    <name>M5G4U8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_92666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632180.1">
        <property type="nucleotide sequence ID" value="XM_040777098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4U8"/>
    <dbReference type="STRING" id="1858805.M5G4U8"/>
    <dbReference type="GeneID" id="63692160"/>
    <dbReference type="HOGENOM" id="CLU_013936_0_0_1"/>
    <dbReference type="OMA" id="HQRKHQD"/>
    <dbReference type="OrthoDB" id="1405595at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="59"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="254"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="805"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="814"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="939" mass="100935" checksum="657FF52206442018" modified="2013-05-29" version="1">MCAPGDPATKYECRLCGSNYSRLEYLKRHERKHQDIRPFKCPKCAKEFARSDVLLRHRRRQHPDDPTLPPVQTHNTSGTGTPPVPSPTSPTAPRRRRRATTNGSSSSNSRVSPPLPPLGVNTQVQPVTSQSSGVTASSGPTLSPDLPSPLEGILHSNSFPLVPPFQLSSPAAAIASGSISPEVLQHIWPEAFSANGLRYGTGASGEYEQDEYGFRTTTNANRYVSSAQSWADAAGFGQGAGNAIAAAAAMGSAQSTSSHSPGSTNLFPSPSLLSDPALATSPPTSVSISPPPGTSPNDGAGVPLEAVLSGGYEDVCMSDVELSAGEASDHDPLAGTGELPLQHQQEQIAQAQAAVNAQAAAAHSAPSPDTQQAAVAAYLQGTSSRDRDAFLAEQTMLKIDGSRMELIRGVCNRDPTDRFYVPPGFFAYCYQVPRWKLPRLSILCSLASRSLNGMLVHLPFVHEPTFRLASLPGPLAFAICSVGGVGGVMSVRPHKPDFNEVASWGQEIMPQVRIEKADMLVRNFHKQKRGMTRLEMLAVVQALMLYNAPSLMSGDDCDRLVGHLFLGTIVTIARQAGLFVATAEHASNAAYSCEHITWLLEPGNDAALERKWKDWILSETYRRAAFLVYILDTLSSLESSIPAIVHPNHVAHIPLPAPDLLWQAQSAREWGVGMTVHHSAQGVSLDQAMKDVLRPVASHSPLGDESAGTSAADDAKFTEMGPFARIIVILTLVRGLMTLGEGEKAGGPVTKRWALEGMTSGKWWNEPEVLEAYQSALQRWKKRWSADRLCPHPFTTATARYSDLPEGLDLDEPLPSPLDPRPAPPHRSSSNSTATPTTPGGGATGTTLSNLSSNQSPQYALVNHASPYYWFAQMLISIIRAHIAAQDPASVGANVDDEQDDQATAGMRNDDQAVPNRFVGTDLRRMLFVAREYGMQHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4W0</accession>
    <name>M5G4W0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FIST domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632195.1">
        <property type="nucleotide sequence ID" value="XM_040769633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4W0"/>
    <dbReference type="GeneID" id="63684695"/>
    <dbReference type="HOGENOM" id="CLU_051231_0_0_1"/>
    <dbReference type="OMA" id="LHRSAFN"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="94"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="378" mass="41664" checksum="F0A832FEBC094A26" modified="2013-05-29" version="1">MNGHVDDGFEPLVNTIRDLSPKHSGCLSAPIPSAPSKIACSISLFPRSQCNTVRTTIPGRKKPQVGRWRIDEPEGRSYAVGSDRYISRQSQAKFELGALDGAAAFVFFSDDMPEGLMDALDYQVPRRIAKLGMISASTPFVTERPFTLFHDQKIYDSGAVGISLKCDVPPRQHVMFQGYTSISSSVQVTDARGNLLHRLNDTSPTQFLLDCIPRMQQRGASQEQAESGFLSKEDEFFVGIPFDVEPQNLQTGYQRVYRITSGDPAKGTMALDADDGPPIGTRVQFLRRSGAWEAHIKRNEDRSLLYQFQSTSDELPPVVEQSLSRGAEHPDMTVVENVFCAASEHGFVSNSLPGMPMGRGRCWRTSVLGAEAELSSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G507</accession>
    <name>M5G507_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625735.1">
        <property type="nucleotide sequence ID" value="XM_040773660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G507"/>
    <dbReference type="GeneID" id="63688722"/>
    <dbReference type="HOGENOM" id="CLU_727663_0_0_1"/>
    <dbReference type="OrthoDB" id="3365472at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="40926" checksum="F5C685B78F2AD1FB" modified="2013-05-29" version="1">MDLLDTAWCPVCDRQIPPEILTAPPTPASPSASPQTNQPIKTRGGTIKAAPGSRRGPMAHLRSKSAAAVPQVQAQPSTSSPPKKEAKPRTYISQAPTPLYCSPECQLRDSMSSLCVSIPSSPTEAKYAAFGRPAPPSSPIMISGSSSSSDAGGSYGSPFSTNSEYFAYLEGRPRRQSHDQPNTGSSAESLSSLNQPTRHLPPTRNADSRSRRPSSSSLAPRPLHSTGYAHSPPTEGKQYTLSFTRAPASTASPSSSPPAISIMPAYASRRDRSASRASSSLREAAGLALPMSPAPSIRSMTRSSSDMTSTPRPFSPIESRSRPTRRKDISPDSGVKILPLKEEEESKWWSWNGYNVPTYEAMPSRSTPDGQRKRMFYFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G593</accession>
    <name>M5G593_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-like ATPase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_87972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630733.1">
        <property type="nucleotide sequence ID" value="XM_040776833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G593"/>
    <dbReference type="STRING" id="1858805.M5G593"/>
    <dbReference type="GeneID" id="63691895"/>
    <dbReference type="HOGENOM" id="CLU_005965_0_3_1"/>
    <dbReference type="OMA" id="NAHNTIT"/>
    <dbReference type="OrthoDB" id="29851at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF32">
        <property type="entry name" value="HEAT SHOCK PROTEIN PDR13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="524"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="625" mass="66074" checksum="1DD89314D3C8404B" modified="2013-05-29" version="1">MSNPISPPPGLANGAATPATAAAIANEEAHSVIGINFGNAYASIAVINKEGRADTIANEDGERQIACAVSFLGSETYIGNQALPQLVKNSGNTILAFRNFLGLSFSEIGEQSPLSAQLKDVDGVPTYVVSVTPEPEGEAQEKTLTVREVTVLFLRSLLQSAQDFLSHRIIKGAVLSCPSDWSVKQRDALLEAAKDAGINVITLMDPAAAAVLAYAPSSASPALPTDTKSAANGSAAPEPHPVPSDRRTLVLDIGASSTTATLLSVSHHSLVHALHQSTDSTLGGKQLDSVLLSHFAKEFSKKSGVALSPTSTTPADLRALAKLRAACELTKRSLSATQGSATLDVESLKDGMDYHGSINSLRFDLLARSVYTRMTDHVRACLGEAKVDPTQIGEVILVGGTASLPGIADALQTLLPDPPTVLSNSIPPGNVVAVGCALHARLTVTHPPPVSAGSEEEQAILKGQALSLPIGLVFPSAGEPVFWQVINAGTPLPARRKVRIPVPSSISKLGFEFWEGKEEVKVETIVPPKVEQDPEDEEEEEEEEEEEEPEEVRTLHLVPSTHLCSLLLPVAHPVLAQEGKKKKSAEKTTEAEVEVVVAQDGKIRARAWVVGQKKVEVVEADVEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5F3</accession>
    <name>M5G5F3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_64373</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630354.1">
        <property type="nucleotide sequence ID" value="XM_040775753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5F3"/>
    <dbReference type="STRING" id="1858805.M5G5F3"/>
    <dbReference type="GeneID" id="63690815"/>
    <dbReference type="HOGENOM" id="CLU_009020_1_1_1"/>
    <dbReference type="OMA" id="DSIHHQR"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="416" mass="45493" checksum="7A2A66C92484D363" modified="2013-05-29" version="1">MLTFPLAMASSGIIPGIFTCIFCGFVAGLGLFYLSRCASKVRPQRSASFYSVAQLAFPAASLFFDLAIAIKCFGVSISYLIIIKGLMPSATKAVFHAMNWGVVPPVLASGRFWVTLITGMLVPLCFLRKLDSLRHTSYVALFSVVYLLLVVIVCYFKPPPGSVPPGEIHLIKLEKDFISTFPVQVFAFTCAQNLFPIYNELHTNTQPRLNLVIGTAVGGATVIYEIIAIFGYLTFGSHVGANIIAMYPETTLFVAVGQVAIVVLVLFSYPLQVLPCRNSLDKVWDDADKVVHKVDRAIEGEEDGGIEPLPIQVHDAHDPSQMGLMKHILLTCIIIAGGFSIAFFVDDLQLVLSFVGSTGSTTISFILPGLLYFQLFRRDRDSTPLLKWGALALAIYGTFILIFCLSFNIYKVVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G640</accession>
    <name>M5G640_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628189.1">
        <property type="nucleotide sequence ID" value="XM_040771159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G640"/>
    <dbReference type="GeneID" id="63686221"/>
    <dbReference type="HOGENOM" id="CLU_1189880_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="233" mass="25630" checksum="E2AC67508E68DA95" modified="2013-05-29" version="1">MHGLKKKKWFSHWHTKQGRSSSILNGQYPLQEIEPTYMHLPKLTKENASGEELNLSRALGQVYKDMVLVDSLEGNGGVSMQNVDDPSTESEDSNGDNNESEEDNKSDQGDSEDGKPKEPQDRPAKKDKKKKRKCKDKGKGRAVKTPAAPAASSSYLHHDHNLECGLPEPDTISKDEPAGNQPSEAANANNPQCIDREELAWDLLRALACFTLWGCDGDMSTIQGSEHGMLSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6D7</accession>
    <name>M5G6D7_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">Phosphosulfolactate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_48861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphosulfolactate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631148.1">
        <property type="nucleotide sequence ID" value="XM_040774871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6D7"/>
    <dbReference type="STRING" id="1858805.M5G6D7"/>
    <dbReference type="GeneID" id="63689933"/>
    <dbReference type="HOGENOM" id="CLU_062679_0_1_1"/>
    <dbReference type="OMA" id="KNQQVEF"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003830">
        <property type="entry name" value="ComA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036112">
        <property type="entry name" value="ComA_synth_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413:SF1">
        <property type="entry name" value="PROTEIN HEAT-STRESS-ASSOCIATED 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02679">
        <property type="entry name" value="ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102110">
        <property type="entry name" value="(2r)-phospho-3-sulfolactate synthase ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27899" checksum="B8E7867AC7800E42" modified="2013-05-29" version="1" fragment="single">IRGPYYAPVTKTYLDELLSDWGEFVDGIKFAGGAFTLMPDNRLKALIDTAHKHDCYLSTGGYIERVLSASAGDKDTVEKYIKKVRDVGFDVLEISSGFLSIPTEDWAEIVRLVKKYGLKPKPEVGIQWGADGDASIEELENAGTRDPKWLIDRAKMFLDAGASMIMIESEGITENVKNWRTYVISAITSALPNDKIMFEAADPEVFAYHIQNQGAHANLFVDHSQIVQLACLRKGIWGTGSTFSRIVTFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6I9</accession>
    <name>M5G6I9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632765.1">
        <property type="nucleotide sequence ID" value="XM_040767911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6I9"/>
    <dbReference type="GeneID" id="63682973"/>
    <dbReference type="HOGENOM" id="CLU_053011_0_0_1"/>
    <dbReference type="OMA" id="STWHTEY"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="42010" checksum="A95F841E99480B5B" modified="2013-05-29" version="1">MPVEYKFLTQEQRDHFLEHGWLKIPNAIQKKYVDDFMSNYWIRMDYDEHDPSTWKEEYVKLPRHRDIPVSEFCPDAYKAICDIVGGEERLDPVRNSMHGDQFIVNNGSEYWEKNEYPPQTAKGWHTDNDWYRQFLDSGEIALTIIHLFTDIEPRGGGTYICEDGMKGVCKFFLKHREGLDPPFPPETYAHIKDCKVFTEMTGKAGDTFITHVYLPHAASQNHIRKPRVISNPHVSLSSPFDFSRPAADLSLVEQVVLRALGRPLSPEEYLPTAPRRSYYPRNYTYKAARIEEELERLTAAAEKQGKGKESVDSVYLRGGEELEAFNLRQGLDKPHGPNKFPEGTRNHIFMESKRAVDNPVEPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6N5</accession>
    <name>M5G6N5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630764.1">
        <property type="nucleotide sequence ID" value="XM_040772327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6N5"/>
    <dbReference type="GeneID" id="63687389"/>
    <dbReference type="HOGENOM" id="CLU_999458_0_0_1"/>
    <dbReference type="OrthoDB" id="10388317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="279" mass="29169" checksum="7F6928E2A8197867" modified="2013-05-29" version="1" fragment="single">MAAFVASVAHPHAHPPPPPAQPQPFLPPPSAVGTAQYPPLSAPVGNTVPTYLSLPPAQPVALPVAPPGAQVVKPVPPPPAPTNASSSPSTNTSPAPLTPLHIAAYALQPWCWRTSRPPASIARVTLRNNFVALSIVGVAWYLGIWGLLWEVVGNLAGEGTEMVLKRLLLLSLLANIAESAYTLSYPPPLSEPLAGTVPSYKPSSLSPAHRKLIERSLSDLPQTSSSPFFSPSRSSLSRSSSLSFSRSPHSLRSSSLPSSVSFSSSLASTLRSADLSDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Q8</accession>
    <name>M5G6Q8_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628404.1">
        <property type="nucleotide sequence ID" value="XM_040768579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Q8"/>
    <dbReference type="GeneID" id="63683641"/>
    <dbReference type="HOGENOM" id="CLU_1266850_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="218" mass="24131" checksum="E24C19B9325E4CAA" modified="2013-05-29" version="1">MQGNGSEEPEQQDAEMDMDEETTEAMLKLQEGDDGENNRIQQSEGAEPNTAQILRPTQQVGKERVASDTHTHTVNQAQPNVNNQIPQNGCERPSTAQMQTQTAEPSATQAQDRHAEPNTAQVQDGPSTPPRPPPDPDTSSPFSPETRAAIRRGKQRADPEPKEEEEEEEEDISSNSEEGMREAQISMDEELARRMQEAEYGGSLAPSNQGHIRFYPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6T3</accession>
    <name>M5G6T3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyltransferase family 18 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_81852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626365.1">
        <property type="nucleotide sequence ID" value="XM_040776533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6T3"/>
    <dbReference type="STRING" id="1858805.M5G6T3"/>
    <dbReference type="GeneID" id="63691595"/>
    <dbReference type="HOGENOM" id="CLU_033184_0_0_1"/>
    <dbReference type="OMA" id="CHADTEN"/>
    <dbReference type="OrthoDB" id="2113294at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030144">
        <property type="term" value="F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026116">
        <property type="entry name" value="GT18_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15024">
        <property type="entry name" value="Glyco_transf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase family 18 catalytic" evidence="1">
        <location>
            <begin position="240"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="395" mass="44673" checksum="030D38F52896FC7F" modified="2013-05-29" version="1">MDITRDTLRLRPSPYLGLLFPEATPEDAKNTDDSNARVLQSLLSCLATATCTENQTKIVLLADSHFALSVRGSVSGEDIWAASVLGALKHLGYSSLYSDNLQSASFYYRMFPDLVKVVFGECEDITNCFGNELCVKSASNLLGIPIWKMFSLHFWNGACHPLGGSWTLSPEDYRGVTRFLGYSLETECMTREVVPPDNRSDQVYVLAKWFRYFFADSYPWPHDALARAVEQTGLQFITGYTNDTETSPLWSPPVVNYGQMPKELFHERLSHSRALLGIGQPYLSPSPYDALCFGVPFINPIDKWDNDDRENRAKWSTQHDGLRFIEEPYVYHVHKRDVDGLVRALRGAKDNPIDRYIPPAMTEASLLDRVVSLLEHDWRSEAQALLNSAVEFLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6X9</accession>
    <name>M5G6X9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626410.1">
        <property type="nucleotide sequence ID" value="XM_040773321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6X9"/>
    <dbReference type="GeneID" id="63688383"/>
    <dbReference type="HOGENOM" id="CLU_1441011_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="188" mass="20343" checksum="0A4AA3E869E2D39A" modified="2013-05-29" version="1">MLEFAPPLSASPSQQQLGAPRHSPSTSTLSTVSLGSLRRQPSDRQRSGTIRSSTGTVPRGSLDAQRAIEARFDSSLAVLSPADQVAGTGNVPPPPPPPPPPPGPSGISRLRPVQPLDPFALDEESYERPRPGAGSSQELVVGRLEPEEQDQERPVRQARAVRGSRADRETREPEREREGKGWRRVPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Z6</accession>
    <name>M5G6Z6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lactoylglutathione lyase</fullName>
            <ecNumber evidence="3">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Aldoketomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ketone-aldehyde mutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Methylglyoxalase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">S-D-lactoylglutathione methylglyoxal lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_99082</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="3"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631378.1">
        <property type="nucleotide sequence ID" value="XM_040777561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Z6"/>
    <dbReference type="STRING" id="1858805.M5G6Z6"/>
    <dbReference type="GeneID" id="63692623"/>
    <dbReference type="HOGENOM" id="CLU_046006_1_1_1"/>
    <dbReference type="OMA" id="THNWDTP"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="VOC" evidence="13">
        <location>
            <begin position="11"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="17869" checksum="C889490E5AC57604" modified="2013-05-29" version="1">MPASSETAGYRFNHTMIRIKDPKASLHFYCDVLGMEQIDTMQGSDFTLYFLAYDTSKGADSAEDKAKYRSSREGLLELTHNHGTESDPNFKGYASGNAEPGRGFGHTCISTPNVEEACARLERLGVPFQKKLTDGRMKNIAFALDPDGYWVEIIGYQERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G792</accession>
    <name>M5G792_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_19405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633000.1">
        <property type="nucleotide sequence ID" value="XM_040771494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G792"/>
    <dbReference type="GeneID" id="63686556"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OMA" id="WVIDAYA"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="99"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="604" mass="64844" checksum="BEE397FADC035028" modified="2013-05-29" version="1">MPAYPSTSGDAGLQPPSATQSMQDERTPDPEPTVVNTPMVSTADLRTTGLSEKAKAAHDDEPRKSEDMDIRKEGPVQAISAFEIPDDKRYLKGSRLFFAFSAMLLSIFLVALDQTITATAIPRIASDFNSLDSITWIASGYFLTQAGFLMLYGQLLIIAPTKWVYITAITIFELGSLICGVAPNVNVLIFGRAFAGIGAAGIFVSILSIIAQITRLEDRPLLFGSFGAVFAVSSVIGPLLGGAFSDHVTWRWCFYINLPIGAISIGVILLIIDARPAIGSDATDGMTTFQRWLYMDWIGALLSIGMVVTLLLPLQWGGNLKPWNDKSVIALFCVFGAVLIMFIAWEWHMGPRAVLPLALFKRSTQIGTCLEAFFVMLGMLLATYYLPLQYQAKGHSATQSGIDILPFMLSVVVVAAISGAVINFTGRYWPFLFFAPLLTCIGAGLLFTLEADAPNARMIGYQILFGAGVGGALQNVVIAIQAEYHDNERMIPQATSLVTFSQLVGGVIGICIAGTIFSNQLSKELAIYAPNLPADVIQGIKDSVTVVQTLPADQQGPIIQAYVKALDYVYLIGVPGGAFGSLSALLTKNHNIKTLGVQFGAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7R1</accession>
    <name>M5G7R1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_86022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633130.1">
        <property type="nucleotide sequence ID" value="XM_040776756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7R1"/>
    <dbReference type="STRING" id="1858805.M5G7R1"/>
    <dbReference type="GeneID" id="63691818"/>
    <dbReference type="HOGENOM" id="CLU_002833_6_2_1"/>
    <dbReference type="OMA" id="PWTKLDH"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067519" evidence="10">
        <location>
            <begin position="21"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="90"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="31"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="48928" checksum="EBD04CEA8CEB2E52" modified="2013-05-29" version="1">MVALRASLFLLPLVATLAGAAPVKQHKVQGRSQCSANASHSHATSVAVTSPTSTSSRTSLSSSHAATTSKTTSSSSASPTSSSAAPSSNTVIAAYYSDWASNIISPEQVDFDRFNWMDFAFAIPDENFNLQFTEDDSEQLLQRLVKAAHAKGKGVKLSIGGWTGSAHFSAAVSSDANRHTFVQNIANLYHQYNLNGIDIDWEYPGIAAASPSNGASPQDTANLLEFFKLLRNTLPSGAVLSAAVQDWPWQDADGNPSNDMSPFAQQLDWITLMNYDVSGSSSTPGSNAPLSDQCGNSIYPQANAMAAVAAWTNAKFPANKIVLGVPSYGYVSQSSVDHLYDKRAYMRRALQVTSDAGSTSDGQIIFRELISQGALTQQGNEWVGDNGFVKNWDDCSATPWLKSTAADQVVTYDDPDSLFVKAQYASQANLRGVNMFDVSGDTASWVLVDALRSGLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G837</accession>
    <name>M5G837_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_23466</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626820.1">
        <property type="nucleotide sequence ID" value="XM_040773250.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G837"/>
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    <dbReference type="OMA" id="WDVCFAD"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tim10-like"/>
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        <property type="entry name" value="Tim10-like_dom_sf"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="6">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9492" checksum="109D908D5E5E9DA3" modified="2013-05-29" version="1">MSTATDEVLEKELASFIEQESARSQVQSSIHTLTDMCWKKCVGSSIGGRFSRGEETCLTNCVDRFLDSSLFIINKVEEARRQAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8C7</accession>
    <name>M5G8C7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RhoGAP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20948</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU04405.1"/>
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        <property type="nucleotide sequence ID" value="XM_040772158.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Rho GTPase activator Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
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        <property type="entry name" value="PKC_DAG/PE"/>
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        <property type="entry name" value="Rho-type_GAP"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075">
        <property type="entry name" value="CHIMERIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075:SF2">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="6">
        <location>
            <begin position="580"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="7">
        <location>
            <begin position="644"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
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        <location>
            <begin position="384"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="846" mass="93185" checksum="4EC73E6A07A3E158" modified="2013-05-29" version="1">MDGSEDAARRADAVLDIADSLPAPEVEADGEDDQSTLAAPALPPMRFSLYGTDFSDILSRVAHSESERNLAELAVVVSPRLAGLQVEPSSAPPGPRSFADMWPSVSRDSGSTARASKDVTPTGLRHIVTSPSMTSIASVDRGTASAPPVTGSFLDGLPPTVRSPSPRISLSHSDASAGEEDDVLGPLSARSLNSSTTPASASPEPVLSAESVLQKMRDAIRDGERQGYVVLDMGSALGMLAAMESMTEKYTDLKSQYDGVKRKSQHYVKGLNVAGAEYDRELTHRREVEAEVTRLRVKVSDQAVRLTMLEAPERESMRLTEHGRVLKEQMDDLQRRVSKLKVERDVTIAEVEELAASKSTASNLEPPSQLHGDALSLRASHSLSQRLEEVKADYAKDLEALQQQRERLAREVQELRDARQQYRDETAMLQTRNDELSALLEQVLAQSDIRPAPTSSPLQRKPSRATPPSALVSPPGSRMRRADESLASVTTASTSTNLTGSLLGQEDRDESQRFVKIEKAELHTQEQPLTATTARRFRWYNKSSSNANVLSTAKAPASSSTTPAPPLPNGQERPNALAAMHNFQQHSILRLTRCEHCAEKMWGLHLRCIDCGIVTHARCQMLVKTSCRRPSMEKTSMEGTVFGRDLIEQARADSRDTPRMVPMIVEKCIEALEERGMDYEGIYRKTGGSSQCKNITQLFEKGPYDAFDLNDTEAYNDVSSITSVLKTWFRSLPNPLFTHALHDKFVSAGENPDQNARGSALTALIKQLPAEHYETVKFLMLHLHRVTNLAEVNRMNSQNLGVVFGPTLMRSQDRSREFSDMSGETQTVRWLIENAPVVFADPEIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8H9</accession>
    <name>M5G8H9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633415.1">
        <property type="nucleotide sequence ID" value="XM_040767759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8H9"/>
    <dbReference type="STRING" id="1858805.M5G8H9"/>
    <dbReference type="GeneID" id="63682821"/>
    <dbReference type="HOGENOM" id="CLU_010595_9_3_1"/>
    <dbReference type="OMA" id="DYPRTHY"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="294" mass="33132" checksum="1EB4984467024418" modified="2013-05-29" version="1">MVITVTTTALAPAERYYTAHTYLLPSDEEERLRQGVWQLYRQHKMLKTDLAWESIPSDLHLKTGDKILDAGTGSGTWAIDMANSVPEGVEITGIDIEKKLFPSPVPNARFLVQSSLDLPKEWSSTFSLIHQRLMVCAFTEDAWNTNIAGFYRCLKPGGQIQLLEIDILRVMSDHLPTPPLTTQWMKALHALCKARNIGPHAIVDVPDILKKVGFEDTQTRKQPMYQNGEAGKAARYASLGSQRALKVPFLKAGGFGIAQTPAEFDTFMDQMEEEWATYEFAWLWIGWTAKKPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8N3</accession>
    <name>M5G8N3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mitochondrial intermediate peptidase</fullName>
            <ecNumber evidence="4">3.4.24.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_13786</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.</text>
            <dbReference type="EC" id="3.4.24.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="4"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631434.1">
        <property type="nucleotide sequence ID" value="XM_040770997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8N3"/>
    <dbReference type="STRING" id="1858805.M5G8N3"/>
    <dbReference type="GeneID" id="63686059"/>
    <dbReference type="HOGENOM" id="CLU_001805_0_0_1"/>
    <dbReference type="OMA" id="ALMFEYM"/>
    <dbReference type="OrthoDB" id="17530at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06457">
        <property type="entry name" value="M3A_MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000055">
        <property type="entry name" value="Related to mitochondrial intermediate peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033851">
        <property type="entry name" value="M3A_MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 13 15" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="14">
        <location>
            <begin position="210"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="693" mass="77852" checksum="45BDA135974F3A7C" modified="2013-05-29" version="1">MSSPAAILELGERTLTRAKVLVTRAKQALGSRTELRRLVKTIDRLSDMLCIVIDTCELVRHAHPDPQVSKSATDVYEYLCSYLNMLNTDIELHNALRAYLMDSEILASTSWDEQQVARLFMYDFEKSGIHLPDDERRQVVELSDTIISLGAKFLHNSGQDRPPYDIGIELLDGMPPSYRREVMSASRSPWRRTLRVTPQSRAHFLITRFAPNEEARRRAFIAVNSSTPNQLATLESLLDARAQLAKLVGYTSYAEMALGNSMAKQPEHVLQFLRTLSEHHKPAAIRNIASIAYRKQLQLQMDFLPSLKPWDRDYYVQLLPHDSPSIPISSYFSLGTTVQGVSRLFTNLYGISLRPAAMAQGEVWHEGVRKLEVVDETEGVIGYVYLDPWTREGKAPGAAHYTVRCSRRVDDDDPLGDSIAAKSDAVDLVVPLEVPSVEMKGRAGKYQLPVIVLMFDIGSSRSLPSLLTWPEVQLVFHEMGHAIHSMIGRTDYHNVSGTRCATDFVELPSILMEHLLSSPACVALFAQHHRTGTPLPYEQLQKMITSLEQFAALDSHHQIMLATLDQILHSSKHEDSTTEWARLHETVGVLPYAPGTSWQTQFGHLYTYGATYYSYLFDRAIASRVFTTVFGGKEGTLDRSMGEKFKEKVLRWGGGKDPWKMIGEVLEDKVIAEGGEAAVIEVGKWGIGDDRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G959</accession>
    <name>M5G959_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleic acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_88779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629301.1">
        <property type="nucleotide sequence ID" value="XM_040776876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G959"/>
    <dbReference type="STRING" id="1858805.M5G959"/>
    <dbReference type="GeneID" id="63691938"/>
    <dbReference type="HOGENOM" id="CLU_762955_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication factor A C-terminal" evidence="1">
        <location>
            <begin position="254"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="41098" checksum="F0502195E1F133DA" modified="2013-05-29" version="1">MTFHDETGEIDAVAWDKAVDLSERLEIGKLYQIPNAKLVDSSDCFTRTNHWLQVQIHSNDKIYELQDSGRILCIFYDFRRINSLEWFNDSRHVDLVAIIVRLGQPIKGMKKFKDQEGNERELITDHVDVYLGDNSGEFVLLAAFDDYGPQFIGREGEVITIKNALIDKYGNSVSLKTKEFTTELLFESGNHAHKVLKEWFESPGSIADTLCLMTGTYSADSVPDSWFTANIPTKTIKEIFTDGIGAHGVRSQVKVRGTVSFYSDREYTYLACPNPNCNKKAQVAESGNSTVWWCTHCKTVYLVPSEKYRLNMQMRDTMGLNNWITAFNGAMERLFGQYACILNAAAAKKYVITIQVNTLEGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9R3</accession>
    <name>M5G9R3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629506.1">
        <property type="nucleotide sequence ID" value="XM_040768311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9R3"/>
    <dbReference type="GeneID" id="63683373"/>
    <dbReference type="HOGENOM" id="CLU_868844_0_0_1"/>
    <dbReference type="OrthoDB" id="10521026at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="320" mass="36499" checksum="53D851A7BAFEBD09" modified="2013-05-29" version="1">MAFAVSQKFTRRSQTAFSFSKGIERNTTRLATYNTLATIQGYEYDLELLSARIHTSDEEVNSATVFSDSEVEMSEVDSSVQSVEQESMEEIDHNSAEESELCAIQEEPVEDSGEEHAHRVDIEHPDHSADCGCSSDEDEKDRICYIQREMSLDEALRLANSTPIFRPAKCHLSWSCACARCKQQRAQKLIQHVTGKLAGTACRLNQGARPDAELKQEQDKRKQQACRETREPLLRRHSLQKEQYSKVQSTGKLATMNRLDRFFLGPTQQVSQSKTSTRKHLHKDIPRRADTHRRQFSMDELEVIELLTDLATVHRKAQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9T2</accession>
    <name>M5G9T2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_108659</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627490.1">
        <property type="nucleotide sequence ID" value="XM_040768696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9T2"/>
    <dbReference type="STRING" id="1858805.M5G9T2"/>
    <dbReference type="GeneID" id="63683758"/>
    <dbReference type="HOGENOM" id="CLU_012358_0_1_1"/>
    <dbReference type="OMA" id="HGVHLCD"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="UniPathway" id="UPA00603">
        <property type="reaction ID" value="UER00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="76"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="474" mass="52789" checksum="3E269604E3B3E187" modified="2013-05-29" version="1">MSPSRPKIIYGPLISPLSKRDIRLSPCSLLSVSSCGVIEWAEHDVDPSSLQEVLAKHGRSLEDRDVEFIQLKWGEWIMPGFVDTHTHAPQFQNNGAGSQYELLDWLKYVTFPEEEKFADVQYAKKMYRRVVRASLDLGTTMCCWYGTLHLEGTKVLADITHELGQRAYVGKCNMDRNSSPTYQEASAEESIADTRSFISYVEALSPSDSTALVRPIITPRFAISCTSKLLTGLGELAAAHPQVPIQTHISENNAEIAYTKTLFPECSTYAEVYDHFGLLRENTILAHGVHLEKSELDLIKRRGAGLSHCPTSNFNLRSGSAHVGQWLDNGNKCGLGTDCSGGWTASMITAMQLASVCSKVVSFYTKGDDATLTGRFSKTQFAKYQLPIPTLFWIATMGGAEVCCLQDTIGSLEPGKQFDAVRVSILPETENMHLWYEESDSLESMLERFMTNGDERNVREVWVKGRKVGGRLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9W2</accession>
    <name>M5G9W2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Maleylacetate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631994.1">
        <property type="nucleotide sequence ID" value="XM_040772018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9W2"/>
    <dbReference type="STRING" id="1858805.M5G9W2"/>
    <dbReference type="GeneID" id="63687080"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_1_1"/>
    <dbReference type="OMA" id="HAMSHQV"/>
    <dbReference type="OrthoDB" id="3360544at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018506">
        <property type="term" value="F:maleylacetate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08177">
        <property type="entry name" value="MAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034786">
        <property type="entry name" value="MAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF105">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="169"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="361" mass="38353" checksum="B3B4B19FA4BB3321" modified="2013-05-29" version="1">MSSFEYNQAPLRVVFGSGTLAKVPAELHRLKVSKPLILCTPEQTFQAEKIEEVVKSGEGITPAGVFPKATMHTPGHITDEALEFLKSSGADSLVSIGGGSTTGLGKALAVRTGLPHLSVPTTYAGSEMTPILGETVGGEKRTRSDPKILPTAVIYDVDLTMTLPSGLSATSGVNAIAHSVEGLYAQNGNPIMSLMALEGIRSLAASLPTVVATPSDVHTRSQALYGAWLCGAVLGNVGMALHHKLCHTLGGSFNLPHAETHTIVLPHALAYNAPAIPEVMHKLADALPGSDGDAIHGLNILLTKLKVKRGLKEFGMKEEDVDKAAEIATRNPYWNPRDIEKDKIREVIRRCWAGEEARADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAM6</accession>
    <name>M5GAM6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_115298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629911.1">
        <property type="nucleotide sequence ID" value="XM_040769974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAM6"/>
    <dbReference type="STRING" id="1858805.M5GAM6"/>
    <dbReference type="GeneID" id="63685036"/>
    <dbReference type="HOGENOM" id="CLU_015536_2_0_1"/>
    <dbReference type="OrthoDB" id="5592486at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067621" evidence="3">
        <location>
            <begin position="36"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="131"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="66095" checksum="6CBDF8B67982CA9E" modified="2013-05-29" version="1">MTSPSLTSLALPPFALLKRLITALSLTSLPAAVSATAQPEHRSIWESLGDGVKAVALRWRWRTTLLEQVESSSTSLPPHIAFSRSHPSNTHPKPPKPPKHSPPPPSIPPTPLYKLYFHPLLFDPLRCPRLPIILCHGLYGFDVKGPSSFPALQSHYWDRVLKVLRGKVGAEVVCPAVPGTGSIIERAEKMHAFLREKLPGREVNFIAHSMGGLDCRHLITHLQPREYTPRSLLTISTPHRGSPVMDWCAANIGVGTALSDAPLPPPPLLPFSLKSPLLTRLPSSTKLTLTLSSLPSSLTSLLLNMVDSPAYANLTTSYLEHSFNPSTPDSPQVKYFSIAARVGQLSILHPLWLPKLLMDAAASLTPDGDEGNDGLVGVKSAKWGEYLGSLEDCDHWEVRGTRGLVRAWEIWGKGEEGKGRGTRASDASTTGNSNSNNANANKERHAHALAHRLTHTLQQNRAELLSRAHELREEALALESQGRMEREERGAVERFGRVLEWVTEGGLGLGGGGSEKGLVVDGGGNGSGLEHMGSGSPSGDEPIPLPAPAASSRPNTTRVAHTTLTTNTNTKATQASQGRAQQEEWRKLPAFDMERFYVALSRKLYDEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAN2</accession>
    <name>M5GAN2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_113532</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632818.1">
        <property type="nucleotide sequence ID" value="XM_040769649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAN2"/>
    <dbReference type="STRING" id="1858805.M5GAN2"/>
    <dbReference type="GeneID" id="63684711"/>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_1"/>
    <dbReference type="OMA" id="WGFKGHV"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000007">
        <property type="entry name" value="Exo-1,4-beta-xylosidase xlnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067712" description="xylan 1,4-beta-xylosidase" evidence="12">
        <location>
            <begin position="27"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="13">
        <location>
            <begin position="684"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="778" mass="84950" checksum="590D8D97AC838785" modified="2013-05-29" version="1">MGSRLSNPRAICTFLLLLALANCVHALFPDCLAGPLANTTVCDSALDPLTRARALVGMLTMAEKFNNTVNASPGVPRLGLPPYNWWSEGLHGVASSPGVTFAPAGQNFSYATSFPEPILMGAAFDDNLIYDIATIISTEARAFNNFNHSGLDFWTPNINPVRDPRWGRSLETPGEDPFHLASYVAKLVTGLQFGGDDPKYQKLVATCKHYAGYDLENWGGYARYGFDAVISNQDLVEYFLPPFQTCARDVNVTSVMCSYNAVNGIPSCANDYLLQSLLRTYWGWEPDSESLNAHYVTSDCDAVSNIYYPHNYTITPEQAVAVSLKAGTDLDCGTFYAEWLPSSYEQGLFHQTDIDRALIRSYAALFLLGYFDPAEGQIYRQYNWANINTDYAQQLAYTAAWEGITLLKNIDDMLPLPSTMTNIALIGPWANATTQMQGNYQGIAPFLHSPLYALQQRGINVTYVLGTNITSNSTAGFAAALAAAQTADLTLYIGGIDITVEAEAMDRVNITWPGNQLDLIAQLANVSTHLIVYQMGGGQIDDTVLLENPKVHGLLWGGYPGQDGGTAMIDILYGSRAPAGRLPLSQYPANFINEVPMTDMRLHPALGTPGRTYKWYSGDLVLPFGYGLHYTTFAKAALKDHSPRSSDIATLVNEAKQSSAWLDKAFFDVFAAEVTNTGSLTSDYVALGYLTGEFGPAPYPKSSLVSYTRLSQVTPGETQVVNFDLTLGSIARADYYGDLYLYPGTYTLVVDVVEPVEVATFYLTGQTTLLNSWPVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAS6</accession>
    <name>M5GAS6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632878.1">
        <property type="nucleotide sequence ID" value="XM_040769515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAS6"/>
    <dbReference type="STRING" id="1858805.M5GAS6"/>
    <dbReference type="GeneID" id="63684577"/>
    <dbReference type="HOGENOM" id="CLU_017235_0_0_1"/>
    <dbReference type="OMA" id="WFSTHAV"/>
    <dbReference type="OrthoDB" id="74813at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="50835" checksum="4BC1B24ECE3C36F5" modified="2013-05-29" version="1" fragment="single">MSSPTRVKVITHAPLPLVRVWFEVSTAVLRGATVRDLKEELCQSIPALADGGLSATNITLEIDEFELLDESGVSVIQNEDLLSIKAKSPPHSIGLPKRRREAVDYFPFQAKRRRVDGVFETNPPRLQNSPANTGDVSSSTPSKTTDEDSSSSGDVSEEENEEENESQSTSSTSTQDSSEFSKSTSAAVDVESGALSNISEMAVQLNGPPPHAIQFSPIAHESTRTQTARPVPPGEGKPSTHARNVRRRKRQALLKAGSTITPHEESTPTLAPESLHQGGNEQHLDGLPYDTPPPEPLPVFSAMAALTLPSKLTNKNKRKGFKKSMDGKAGQKIIFGSPSRHHRLIPPSEKGDIPHNMFITSVDCSARETISMEMIDHATILSSSDWDRIEGKFDSYEKVSSLTDLTTGDVVAWQALALNQRTCSPEVMLHLATVVAVSRQEENTCTVSFLQRPEKRSHDEEDDASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAT0</accession>
    <name>M5GAT0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GAMM1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629976.1">
        <property type="nucleotide sequence ID" value="XM_040769985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAT0"/>
    <dbReference type="STRING" id="1858805.M5GAT0"/>
    <dbReference type="GeneID" id="63685047"/>
    <dbReference type="HOGENOM" id="CLU_051576_0_0_1"/>
    <dbReference type="OMA" id="FHCDEVV"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="328" mass="36996" checksum="8561691565E29334" modified="2013-05-29" version="1">MAVAKAIGTHDGTFHCDEALAVYLLRQLPTYANASLTRTREPAKLDSCDIVVDVGSVYDPSKQRYDHHQRGFTEVFGHGYVTKLSSAGLVYKHFGKELVALRIKKPVEDPIVELLWLKLYKEFIEAVDANDNGINQYPTDIEARYRLNTSLSSRVSYLNPAWNEPATSDISDAQFLKASELTGKEFYERLDYYAKAWLPARDIIERAMESRKDVDPSGRILVFETFCPWKEHLFELENEMGIPEAENTLYVLYPDTSSHTWRIQAVGVSPNSFASRKALPEPWRGVRDDDLSTLSGIPGCTFVHASGFIGGNKTKEGAMEMARQALKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAV9</accession>
    <name>M5GAV9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627965.1">
        <property type="nucleotide sequence ID" value="XM_040772989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAV9"/>
    <dbReference type="STRING" id="1858805.M5GAV9"/>
    <dbReference type="GeneID" id="63688051"/>
    <dbReference type="HOGENOM" id="CLU_083400_1_0_1"/>
    <dbReference type="OMA" id="FARELWF"/>
    <dbReference type="OrthoDB" id="5564877at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473:SF1">
        <property type="entry name" value="DINB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="198" mass="22463" checksum="A219CF3BEB274FFB" modified="2013-05-29" version="1">MSAQTYDDTGSVQDRPLEQYIFVSTAILQQGVDLLKNVLKEDEQLVYDSKMLPGSSIGKHLRHARDYFNLLLLCLSRPKPLQLNYDIRSRNVPMETSRRIAALELEGTIKQLRDLQEKGQSILDEPITLEAVTPFKQVMQTTVGRELWFAGLHAIHHWSMIRLIAAGEMGIELEHSFGVAPSTLQHRGHEGITTKARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB58</accession>
    <name>M5GB58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_40124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633063.1">
        <property type="nucleotide sequence ID" value="XM_040774472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB58"/>
    <dbReference type="STRING" id="1858805.M5GB58"/>
    <dbReference type="GeneID" id="63689534"/>
    <dbReference type="HOGENOM" id="CLU_037236_0_1_1"/>
    <dbReference type="OMA" id="RRYDYFY"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="30213" checksum="04648333CD8C889B" modified="2013-05-29" version="1" fragment="single">EDYEIFDLVSALEAAEGKGTTFYSWLDVPSTATSTEIGRAYRKKSLELHPDKNPGVKGIHDRFARLGVIAKILRDGEGRERYDFFYKNGVPKWRGTGYYYSRYRPGLVSVSIFLIFLSSALQYIVQMMTHRREVDHVRKLVTQARAVAWGPKGTPLDGPRKVRVSLGEGEGIKAVDVLVHGEGVFLLGNDDHETVPLDESVPLKPAVSRTWPVVLVRAAIEPIMSRFASAPKVKTDDDADESDASTVKANGNGIKKLPTAAASMAGGRRRKAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB74</accession>
    <name>M5GB74_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630171.1">
        <property type="nucleotide sequence ID" value="XM_040772421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB74"/>
    <dbReference type="STRING" id="1858805.M5GB74"/>
    <dbReference type="GeneID" id="63687483"/>
    <dbReference type="HOGENOM" id="CLU_371721_0_0_1"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="748" mass="81594" checksum="C60B59B98B2056C6" modified="2013-05-29" version="1">MSPSTLPVSRRHERGGSTTLTLETTVGIESSAVGYYPTLLLKGSDATSEEQGEKKTQKNVITKIQDAKGEKDEEERPKEKDENLQAELISPRETRRNALENVLEAMMAVEEAQEHVEAPGERRRKALESVLEAMIVDEHEETEASASPQPEADLEASCIPGSSSPRSTRHGSSRNILVESPEDGITAGPSRIYARETEAIYLPSRDTSRPDPTDVPPTPRAAELALRTRFAMEEMYMSPRVLSKQPERQSTMDQQDALWGLAEAAASAAARQTQKELADLIGESDSCSGERRGLNERVVRAAEVARVIRKMYHLAWELEVEVDSANDVGTSKAGAGSRPGTGNSKPRPDPIEKAQDICQISQASQASDSRSDNQSNPPAPVLPHAPAVENKVAGIRLWLEDVQSQLADSPDLPSSAWAGKISLAHSPEPENTYEKTLVGDVLSVPNKLNDQPLDDVVERVSLTAELPIRAWIRELLRRTDVSSSQLKVAACYIVALRPHITLAMVQRQQAAHAVVRGTPLTHYQASPLTCPRRTLVGALVLASKFLGEKIYSLRAWARVTGLEPGDLVQAEQIIGTALKWDLWVGANVQNLRSDVFTRMLLQIVSVPKVEPPPAVRGARPKEQSSSRTGALPRTEGDIALQRSRKQTVGSPTSSTQRETVASPSPFGAKRTPAMDHQLEHALHRKRPAPESDTHPLSDTRPQKRKNVEHVHAHAHSHGTNGAAGAGCGTDVYIKSEPVDERGLLTEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB75</accession>
    <name>M5GB75_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Tryptophan synthase</fullName>
            <ecNumber evidence="5 13">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_20071</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the TrpB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5 13"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632539.1">
        <property type="nucleotide sequence ID" value="XM_040771783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB75"/>
    <dbReference type="STRING" id="1858805.M5GB75"/>
    <dbReference type="GeneID" id="63686845"/>
    <dbReference type="HOGENOM" id="CLU_016734_2_0_1"/>
    <dbReference type="OMA" id="VDTARHS"/>
    <dbReference type="OrthoDB" id="10050244at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000151">
        <property type="entry name" value="Tryptophan synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000001">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000004">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="14">
        <location>
            <begin position="360"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="710" mass="76062" checksum="E7EF5C90A93C198D" modified="2013-05-29" version="1">MTESLKRVFATKKAQGAPAFVTFVTAGYPSPTDTVPLMFAMAQGGADIIELGVPFSDPIADGPAIQDSNNVALQHDVSYAQVLGMLKDARNKGLQTPVLLMGYYNPLLSYGEEKAVQDAREAGANGFIMVDLPPEEAIRFRSICAKEGISYVPLVAPSTSLQRIKFLASIADSFIYVVSKMGTTGSSAEVAMNVELPQLLSRIRAYTPVPLAVGFGVATRAHFESVAAAGSDGVVVGSRIVSLIKGSKSPKDALDTVRAFCAELTQHAGAMPTPPHLANGAGVQVVQPPPALPIPPAPAPDSLKVTEAGHLPGRFGAFGGQYVPEALVDALAELEQAHLTALADPEFWKEFESFYGYINRPSRLYHAERLSKHAGGANIWFKREDLNHTGSHKINNAIGQILLARRLGKKRIIAETGAGQHGVATATACARFGLECVVYMGAEDVRRQALNVFRMRMLGAKVIPVNSGSKTLKDAINEAMRDWVTNLSTTHYLVGSAIGPHPFPTIVRDFQRVIGREIKQQMAEIKGKLPDVVVACVGGGSNAIGTFYDFIQEPGVRLFGVEAGGDGVDTQRHSATLALGTPGVLHGVRTYLLQSPTGQIIETHSISAGLDYPGVGPEHAWLKDSGRAQYIVATDEEALRGFRMCTQLEGIIPALESAHAIWGAVQIAKTLPKEQDVVLCLSGRGDKDVEQISEILPGKWADKLDWHIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBG4</accession>
    <name>M5GBG4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exocyst complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_113023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633188.1">
        <property type="nucleotide sequence ID" value="XM_040769547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBG4"/>
    <dbReference type="STRING" id="1858805.M5GBG4"/>
    <dbReference type="GeneID" id="63684609"/>
    <dbReference type="HOGENOM" id="CLU_008002_0_0_1"/>
    <dbReference type="OMA" id="PLCKHHY"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="6">
        <location>
            <begin position="55"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="5">
        <location>
            <begin position="181"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="900" mass="100672" checksum="C7CEC887D48A4F98" modified="2013-05-29" version="1">MAVNRSNSLFATDQAVDELLQLKTFEDRFDVREFVSSISERLIAHSKEDAGPFDPKPFIRTFESSVDRLLSIRRDLQKQTEVMENSVRNAERDYSKRMSELNSGFESVGKSFSSMETKIGEVGRTAIRIGEQLENIHQSRQRAQAAYDLIDYYNQFAKGDVTRLEALRKERGKEREGREKVAIICRRLSALAKEVDVIGAEKTRENIERYCEKFEKDILRLFDRSYRKGEPKMMAHCAQILLDFNGGNSCIQIYVNQHEFFISAASVEPSSLETEEIWKSISSPTPPPPRTEPSLSLLLQKIRSTVTEEAQIVQAVFPNPMQVLQVFIQRVFAQLIQRQVEMLLEQASNLSSLAFLRMLHLCHAQISRLVDDLKGYDFSSPTSILGKASLGAIPSGPGNLSGVLETAMEELFIPYTEGTRWLDRECKSLAELYAGFLLRFSRYHAQAHQTTKTDGLMNRFMSQISTSTSNVTSNMANAVQGNATTAQAAAAFMKVTGLGTAGGSQLDKRQSDVVVEEPLRELDGKLTIGAAETMLKWHAEAVGRCVELSPSGDVGKNAFALLRLISETLGRSYIETAIDSAIYKLESRDPKLEPELTPLHVVKTIDFVCHLWQQYVNTAILPLAGSSVTVRREMVVYNNSVMNRVETSMDTLVQKAIDVVLAWLAAQLAKQKRNDFRPRNDDMTFARASTEPCTACCDLLVRLKDASKESLTGKNQETFLTEIGVSFQSMLLEHLKKFSVSALGGLMLTKDLAMYQDAMSKYSIPIINERFEFIRQLGNLFVVQPTTLKSYISDSILNRVDPILLRPYLAQRSDWAQISAGWEGIIPNSAASTEDGFLNTTQNLRERLGAGLGSIMRELENFRNGGDEDFYSPPPTSAVFAQSRTSYPVPSPSIGTLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCX0</accession>
    <name>M5GCX0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_107739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628915.1">
        <property type="nucleotide sequence ID" value="XM_040768522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCX0"/>
    <dbReference type="STRING" id="1858805.M5GCX0"/>
    <dbReference type="GeneID" id="63683584"/>
    <dbReference type="HOGENOM" id="CLU_050573_3_0_1"/>
    <dbReference type="OMA" id="IEWIVAF"/>
    <dbReference type="OrthoDB" id="10032492at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="37902" checksum="C4F1F7B97B85AA4D" modified="2013-05-29" version="1">MPLPRRLSKVRIHFHPSWVPVIPIIAWFVTLWALLGWWLNSGRPKLPSMEESIAYISDIGATFLKPLFIVGCIITGLGFFATLLVDALLRRAGILERAGRRRVRWISYASIASSAVGAIGLIFLSGFDTLRCPTEHDAFLLVFMVGVIFSAIFTILEYAFLLRSPQVHRTRLLEASFYGKILVFLVELGLAIAFGICLNTNNLYNTGAIIEWIVAFVFEFYLVTFWMDLHPANAVIERECGDVEARVVDPTMTGTAGAGRTLVAPRFSHPRGIGAPAVTAAPAGAPPMASVAPAPAHANATTLQADGVPSYPTPTATIPARSAGTLEPPRVTIPRLAAHKPAQAAIPVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDF1</accession>
    <name>M5GDF1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_76971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631376.1">
        <property type="nucleotide sequence ID" value="XM_040776240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDF1"/>
    <dbReference type="STRING" id="1858805.M5GDF1"/>
    <dbReference type="GeneID" id="63691302"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_11_1"/>
    <dbReference type="OMA" id="LAINGAH"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF8">
        <property type="entry name" value="BENZIL REDUCTASE ((S)-BENZOIN FORMING) IRC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="26515" checksum="1448C7A1CA2E756B" modified="2013-05-29" version="1">MAGQARVILTGAGGGIGLAICTILLEEFGAKVVAIDINVSDALKALKEKHPESLQIVHGDITKPETSLEALKLEPSPTALMLNAGVCELVPIASSTPAHWSKVFNVNVLALLNTLIPAVPALRENKGRVVFTSSSAATKRRGAWASYNASKAAENAIARTFATEEPDITSIAVCPGMADTGMVERIRGKMGASAMKPDDHQFFVDAKKNMINPKDCGYVLANLAINGAHELSGEFFTWDSPQGAPYKRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDH4</accession>
    <name>M5GDH4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629292.1">
        <property type="nucleotide sequence ID" value="XM_040768445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDH4"/>
    <dbReference type="GeneID" id="63683507"/>
    <dbReference type="HOGENOM" id="CLU_1686506_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="15865" checksum="167D4773B3DC656D" modified="2013-05-29" version="1">MPGPIPIPIPRAGRSCSRSRGTDCSLPPPPAAGKGLPTPNPESAFLFPNSSNSSNPGSRRLPRLASPNFPSLLTIVGGLGLPSGSVRGRSPALALEVWAEWGGEGEGVRGCLWAWEGAADEGKGEGREGGADLFLAGEIFPPPPPPPTAPASGADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDH9</accession>
    <name>M5GDH9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_116102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629307.1">
        <property type="nucleotide sequence ID" value="XM_040770135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDH9"/>
    <dbReference type="STRING" id="1858805.M5GDH9"/>
    <dbReference type="ESTHER" id="dacsp-m5gdh9">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63685197"/>
    <dbReference type="HOGENOM" id="CLU_006586_15_2_1"/>
    <dbReference type="OMA" id="FAACDFW"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012587695" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="25"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="363"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="521" mass="55096" checksum="6165B46761FCF07A" modified="2013-05-29" version="1">MLSLSVAFLALSAHASPIFSRDDGTLVTTAQGAVQGTLVTPTVRQWLGIPYAAPPTGTSRFAAPQPAPSWSSTLSASAFGNSCPSVLDTEFLTIIGLLQQQESIAYDEDCLNLNIWAPATSRPQGGAVMLWVYGGGDMFGSSNTPYYSGTTFVEDHDDLVIVTFNYRMDIFGFPNAPQQLTNVGLLDLDAAIQWVYANIAAFGGDPERITIFGESAGALAVDAYAFSHPTDTVVKGIIAESGTAQLTSILQIGSTSPSETNSSWNTVANALGCGTAGDAAQLACMQAVPWQTLLSEVVSGGESFTPYPDGQTIFSDVSTRSSNGEFLKVPFLVGNNANEGDIFAVAFEEGDFGNTIPVATTVLSDAVTEVVFLCPASKAANDRTNAGVATWRYRFEGVYLDATNNNADLRAFHTVEVPMVFGTYNLSTFSYAPVSNEIALSAWMQSAWVTFAQNPVSGLSSYGWTQYSTNILSSTIARLGNSDNPSGATYSPPIDFDVGCGAVNALTPYVIDLIDDLGSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE03</accession>
    <name>M5GE03_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rds1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_78763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629752.1">
        <property type="nucleotide sequence ID" value="XM_040776357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE03"/>
    <dbReference type="STRING" id="1858805.M5GE03"/>
    <dbReference type="GeneID" id="63691419"/>
    <dbReference type="HOGENOM" id="CLU_028606_0_0_1"/>
    <dbReference type="OMA" id="VYGFLNH"/>
    <dbReference type="OrthoDB" id="2098436at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067766" description="Rds1 protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40314" checksum="EC6916E7F1F95C1E" modified="2013-05-29" version="1">MLSVITLLTAALLANAWPAPVAPYTPSGGVGVSPDSPAPKYEPYSDFDFQSLNLALNQEWIELDLFYKGLEMFTLKDYEDAGLNSQDRELVEFMAEQERGHAQLITDMLGPRAAKECTYTYPFKTVPEFVDSCQKLTRFGESGVYGFLPHLNSRPTAQLLLQSITTEARQQMIFRQFEGLFPMPVWFETGITQSMAWTLLAPYIATCPDDNPKIEWQNFPALDIIDNPWAPDPAYPPAITHNRTALSTPRQKVSFTWENPGKKVGYNDLYTTSTSAGKPKFAAWISQLNTTYTPLNDISGNSAWTYQPDGTVFVIEGYYDPIVNETMFILITDTDLHVTPYNISLLNDHVVAGPAIYQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GED7</accession>
    <name>M5GED7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_113482</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632226.1">
        <property type="nucleotide sequence ID" value="XM_040769636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GED7"/>
    <dbReference type="STRING" id="1858805.M5GED7"/>
    <dbReference type="GeneID" id="63684698"/>
    <dbReference type="HOGENOM" id="CLU_073388_0_0_1"/>
    <dbReference type="OMA" id="FLTREWG"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="31068" checksum="6ACFCE0D6D2FE18B" modified="2013-05-29" version="1">MDAKQEQPPSTPLLVAVEEFSRQHTTLLAALFGLLLAIVVTLFLVNRKSQKNKIRNVLLVGPLESGKTALFANMVYEQHLPSHTSLQPNIGLLQQDKKTFRLIDIPGHPRIRSRFREHLATVDGLVFTVDANTVARNGVAVAEHLHLVLSAVQPLSRSPRLLLLATHADLVEHGSHPAVEPVLHPARIRVVSVLEREVEKRRLAGANQKLGGAMEALGAVAGGGKQGLFGSSSAGGTGEGEEIPDGTLEVGRDGVWRFGDEWEIGVSSVGSGDRTEGLRSIVDWLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEG9</accession>
    <name>M5GEG9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632311.1">
        <property type="nucleotide sequence ID" value="XM_040767838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEG9"/>
    <dbReference type="GeneID" id="63682900"/>
    <dbReference type="HOGENOM" id="CLU_1402380_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="21672" checksum="24B03CFCE8135E19" modified="2013-05-29" version="1">MNDVTKLYANQPSNDVQRRFMNDAKTYHDAARIACVATSHPEVFPATAPAPAALLNRVMEELRTLNAKLDAQSTKLDAQSRGIHNIESQMKQQGKTLRELDIRSAKMHNRTVGDGTEPAYLIVKRLSDDENPPSLIYSMADLLALNLDQAMAVCHFYDSHFRTAGNRELGSCRVFIARSIGVHTHVVMDIPMDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF65</accession>
    <name>M5GF65_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_106040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630777.1">
        <property type="nucleotide sequence ID" value="XM_040768188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF65"/>
    <dbReference type="GeneID" id="63683250"/>
    <dbReference type="HOGENOM" id="CLU_015166_16_0_1"/>
    <dbReference type="OMA" id="CAGMSFW"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="32"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="128"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="215"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="32988" checksum="D2C519E9B8FF0285" modified="2013-05-29" version="1">MSFPTDPREEKSITHAALGDGDVGKTTLPQWRLLMNEYLAGTVGGMAGLVVGYPFDTVKVRLQNPETAGKYTHGIWSTFGRIVAEERFLGLFKGIASPMATLAPLNGLVFGGYGYFLRLQSSASGQVPTLWQVTVAGTLTGIAASTITAPTELIKIRQQTLISTGIPSTWSVVRTIYSKHGIPGLYRGITATVLRDAGYGPYFLAYELTTRLSPSSPVTPLFAGAIAGIIGWTATFPLDVLKTRIQSFDADGSGPYRSTWSTAVHSWQEEGWGVFWRGLWPTVVRAVPVNMATFGAFELALRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG80</accession>
    <name>M5GG80_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetyl-coenzyme A acyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_76062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631917.1">
        <property type="nucleotide sequence ID" value="XM_040776176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG80"/>
    <dbReference type="STRING" id="1858805.M5GG80"/>
    <dbReference type="GeneID" id="63691238"/>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_1"/>
    <dbReference type="OMA" id="MPEAYVI"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF107">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="7">
        <location>
            <begin position="284"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="42691" checksum="CDE050B05931B367" modified="2013-05-29" version="1">MAASRSSPQAFVVASKRTPFGTFGGKLRDHKASELGGFASKAALDTLPKDVQVDSVVFGNVVQTDTSGAYLARHVGHYAHLPVTVPALTLNRLCGSGFQSVITAAQQIQLGESNVVLTGGAENMSMAPYTLHGSVRWGTKYGVDQKLVDSLAASLVDQVTGDRGHWKPTPMGVTAENLAKKYGISRADCDAYALQSQQRWAAAQEAGAFKNEIAPMEITHKRTSTVFDKDEHPRPSSTLESLGKLGPVFHKEEGVVTAGNSSGIGDGAAANVVASEDVVKQHNLKPLARIVSWGITACEPTIMGIGPVEAIKMALSRAGKNLSEIGIIDVNEAFAAQFLSVAKGLELPMDRTNMFGGAIALAHPLGASGARIVANLVHNMQRLDVKYGLGAACIGGGQGIAVLLEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGJ7</accession>
    <name>M5GGJ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">mRNA splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17563" checksum="93A5DEFD110E4602" modified="2013-05-29" version="1">MSLAEAAEARKARLHALRKRKLGENGQEAVNGEEPPLKQRAFDPETRALRRHGDVDEEDTVEKNVDGLAQLIIQEDEEKRAEDLDLFNIAPKRPNWDLKRELEKKLAKLERKTQEAIHTLIRQRLQSQKGGTADLSLSMAAENGTTAQDNSDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGW2</accession>
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        <submittedName>
            <fullName evidence="3">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19460</name>
    </gene>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040771520.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5GGW2"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF30">
        <property type="entry name" value="PHOSPHORYLASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="318"/>
        </location>
    </feature>
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        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="374" mass="39754" checksum="C2BC7DBB24193438" modified="2013-05-29" version="1">MALAYVHSCGVLHTDVKPQNVLLSYTTPPGRDSGLTLNAGAGPVQVEYSARLADFGSALLLPPFTASSPTDGLGLGTPGYTAPELLLPPGSCSFSYSADVFSLGVVLGVLLFGREPYARLVGRGRGRLEMMRWAKKGGYWAYEEGVRLASVGELGQPRGEDEAGEEERVPRLGRNDLLELLANDGTERQEEELEEREDVVWPSPPELKLDPSSSEDSLTPGAANVEERNIPELVLSRVPHHLSGNPMVPLGVKEPIPLPSPPNSPPKSAANATTAHAHTRTRTSLHTPTTHSSQGVLSPPPPLTSPATPSAPYADGSPPIFFLGPSTLTGQPERAPDALVSLVKRMCSPNSEGRPEMDEVVSVLGALREAYCLV</sequence>
</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633532.1">
        <property type="nucleotide sequence ID" value="XM_040777086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH53"/>
    <dbReference type="STRING" id="1858805.M5GH53"/>
    <dbReference type="GeneID" id="63692148"/>
    <dbReference type="HOGENOM" id="CLU_1073711_0_0_1"/>
    <dbReference type="OrthoDB" id="4584900at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067848" description="Concanavalin A-like lectin/glucanase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="27853" checksum="F2B643DAB8E40F81" modified="2013-05-29" version="1">MNFRAVILLLLATYVSALAVPPVMWTLEEGWTNAKRFAANLAPLKPKSLYAPTKVLASRHSASPSPSPSSGPTSVCSGFVSVYSVGQGPSGWLSATVMNATGVYSTTTMDKSQALKVSIPCITKDHSALKAYNGPDKKTCYVGFIQEEDEPDIGAGSENFGLIGPTAWTDSGAKPAVGDNYYDVITDDPTLIEASVWKYNSKTTELTAAWINTDGSSVPSTLFWDTDYYWFGFTGDLGKLISEYGSGNNFVQVKFYLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN96</accession>
    <name>M5FN96_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_91736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623958.1">
        <property type="nucleotide sequence ID" value="XM_040777020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN96"/>
    <dbReference type="GeneID" id="63692082"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="TYVMEVC"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF24">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="529" mass="58892" checksum="0986A967052A8B49" modified="2013-05-29" version="1">MVGHAPTSFERRIADVLPPRKGWWNYWYLWRLNFALLSSILSQATGGYDGSLLNGLQSLPLWTSYFNHPAGANLGVLNVALSIGQSVSTLIAGFLCDMFGRRIPLGIGCWLVIIGSVIGAAAANFGMFLGARILVGFGCGLQQVASSSLLAELSHPSQRVQVQTMFAPSYPLGGIVAAWVTYATYAYSTTWSWRLPLVLQAVFALLQFICLLFCPESPRWLIATGKRQKAIDVLVKHHANGDIDSPLVELEVAEIDSQIEADSIAKAYSWMEFFKTKGSRRRFYIMCFFPFARQFTGSNLISYFLPLVLNSVGITNSKEQLILNGGVNICAFLFGISAFLYVDYFGRRLVLILPMALCAASLVVWTILGALMDNSSNTGLGYGIVAMVFWFQGWIHVFDAAAEPYIQEMSTFALRSKIVVMWQFGQQVVYYISSFANPVAMPELGWRYIIIYAVLDAVYSLVMFLFFPETKGLSLEECVLVFDGEEGVERQLAAEKEFEQMRNAHSVAYADRELLNASVIQTHLYICKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNZ1</accession>
    <name>M5FNZ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_40738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624978.1">
        <property type="nucleotide sequence ID" value="XM_040774490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNZ1"/>
    <dbReference type="GeneID" id="63689552"/>
    <dbReference type="HOGENOM" id="CLU_013084_4_2_1"/>
    <dbReference type="OMA" id="KCAQEEI"/>
    <dbReference type="OrthoDB" id="2676448at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12961" checksum="641CC91F3814140C" modified="2013-05-29" version="1" fragment="single">LECLVVQRLFEMEKMDARGTNYKMRSSIAKALQTRSSSIRTTLMEYNHLAPLVTPSQPMLTMSAILDHAFQGEFMILRHGSSPDDLSRHWMQPQIRELVVKWLLVKCAQEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP50</accession>
    <name>M5FP50_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625113.1">
        <property type="nucleotide sequence ID" value="XM_040769188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP50"/>
    <dbReference type="GeneID" id="63684250"/>
    <dbReference type="HOGENOM" id="CLU_1815721_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="142" mass="15321" checksum="B2AD54AD2D768127" modified="2013-05-29" version="1">MLVTLTYSSGAHVTRNLVDVAPLEAIRGAIVDLFEHFNGMGGWAEDDEPLVSALVEYPVATAVDESASANHLQVSKPTQAVKSSAIANHLQLSEDQKRHEECMEAGAQIAYLLYRVAIAPADVVENIAMGFWGYISQCGALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPA8</accession>
    <name>M5FPA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625283.1">
        <property type="nucleotide sequence ID" value="XM_040770636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPA8"/>
    <dbReference type="GeneID" id="63685698"/>
    <dbReference type="HOGENOM" id="CLU_566242_0_0_1"/>
    <dbReference type="OMA" id="WSYEPIY"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052301">
        <property type="entry name" value="SCF_F-box/WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14381">
        <property type="entry name" value="DACTYLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14381:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067116" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="462" mass="50885" checksum="F2419F654C2AA9D3" modified="2013-05-29" version="1">MSMITLPVEILLAICHELEAYELCSLSRTCRKLHELIEGLAWKDYLLRHPRSSITHRINSSPQQQAAYNHAVDHSWHSRSYVACAFSEAWHRVGPALALTSNRLAVGAGEQIHLFPVLGNSHSGQLESPLTHRIHARDARRDVTAIAFLPDGEQGRTLLIGRADGLVQRYHLSPDERTLHATARYDHPTSCVLSLSVVNDTAVTAARNGVVSFIPTCSPWIQPSTLQVHSKPWSVHFSPDRNMLAVGTIGQHPLNVYFVLPSGPLSSHRRAVLSGPARASAVYGITHAPSGSIWGSSSSQVFVSGWFDGKTRVHDMRQKDRTACLSLSDPWDDSPVYAVAAGGGGSCHIAAGSSRHGIVRLWDVRQPKAGWSAFSPGKDNSPVYSLVMESSRVFGVTESRAFVMDFDPSARPSDYPPTPIAMKNAVRENDQSLLGEWTPHYLHCMTKIDISRQPARRERRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPF2</accession>
    <name>M5FPF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">YlMBF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_91026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MBF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625408.1">
        <property type="nucleotide sequence ID" value="XM_040776989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPF2"/>
    <dbReference type="STRING" id="1858805.M5FPF2"/>
    <dbReference type="GeneID" id="63692051"/>
    <dbReference type="HOGENOM" id="CLU_112609_0_1_1"/>
    <dbReference type="OMA" id="GKNKSCK"/>
    <dbReference type="OrthoDB" id="10253401at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013729">
        <property type="entry name" value="MBF1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF15">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08523">
        <property type="entry name" value="MBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="7">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="16043" checksum="D706E1A43DF13AB8" modified="2013-05-29" version="1">MSDWDAKLVIGSKAKVPKVTRSESELNSARRSGAVVSSDKKITAGSNKAHAGTDHQRIAKLDRENEVAPPTKVAPSVGRAIMDARASLTPPLSQKDLAQKINEKPSVIADYESGRAIPNPQVLGKMERILKVKLRGADVGKKLDTPGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQB8</accession>
    <name>M5FQB8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT97628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624526.1">
        <property type="nucleotide sequence ID" value="XM_040773959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQB8"/>
    <dbReference type="GeneID" id="63689021"/>
    <dbReference type="HOGENOM" id="CLU_119615_0_0_1"/>
    <dbReference type="OrthoDB" id="3404535at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="23494" checksum="02829944784C9476" modified="2013-05-29" version="1">MQDAARRHDENWKVPANFRAELKKDVYMYLLSPKCPSYVQSACNIMMDHCRRSHVRMHLEEEWFDDETKRAEIFSTISRTLTDRRNFVQNKLLFSMPSRAPYPAPTYTSQCMIYGCSWEKYLTSNLVVVQGKFTLKPWPFEYDLSHWVRYAFLREIMRQHSQLGDTTVTNAQGKEEKVPKEYFLYVDHCMKAAKEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQR2</accession>
    <name>M5FQR2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Glycoside hydrolase/deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_25234</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624007.1">
        <property type="nucleotide sequence ID" value="XM_040774075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQR2"/>
    <dbReference type="STRING" id="1858805.M5FQR2"/>
    <dbReference type="GeneID" id="63689137"/>
    <dbReference type="HOGENOM" id="CLU_472527_0_0_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067196" evidence="13">
        <location>
            <begin position="18"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="14">
        <location>
            <begin position="47"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="258"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="577" mass="61771" checksum="BE95654F75494546" modified="2013-05-29" version="1">MHFLASTLLCAASLAAAIPITPRLNARKLPLTGRAEATVYSNCVQPNMVALTFDDGPWIYEADIVGKLNAAGIHGTFFVNGMNYDCIYNYIDQIRSAHEAGHMYGDHTWDHTDLTTLNYQSISNELYGVELALQRIIGVQPAFMRPPYGSYNDLALQVIADHGMSAVMWDFDDGDSTGSSVSESEADYANTVASHPSNLLALNHETYETSADDVLPYAINLLKNAGYTFGTVAECLGGLQPYQWTTSYGNQDSSWNCNSMPVGPSGPTTTTHTSTSTSSTTTSTPTPGPPRYIQSYRNGQCLAISGSAGDGTPVVTVPCASANKWDISPGDGLVRLDGTNYCLDAGVGPHNNVPMKIWTCYPGLTQQQWTETSDNRIAITGGDQCLDEGPTGPQTYQCTAYNTNQIWYALATPPTSSTTTSTSTSSSSSAGPAPTGNVLHPNGDTTRCLTVASNNPYNGQVVQISDCFASSSPYYPMQLWSIARGSGSVRLAGTNYCLDAGTSPANGIGMKVWQCYDGLMQQTWYYTDDNRIAITGGTMCLDVTKESGPAPGSPYGSDQAVQTWQCTASDNQQVFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRU5</accession>
    <name>M5FRU5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_118741</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625376.1">
        <property type="nucleotide sequence ID" value="XM_040770650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRU5"/>
    <dbReference type="STRING" id="1858805.M5FRU5"/>
    <dbReference type="GeneID" id="63685712"/>
    <dbReference type="HOGENOM" id="CLU_008515_0_0_1"/>
    <dbReference type="OMA" id="HRVCHIC"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="640"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="640"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="674"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="819" mass="86696" checksum="29D7A04CB07712BE" modified="2013-05-29" version="1">MPSKSTPASGTATLSSILAARSPPPGLASPNPDADEDIDDGDSAVCHICANAITYISLSPCLHTTCHTCALRLRALYKSQSCTVCKQPQPRLLFLLPSTLPNPGSLGVTTQEDREKVFDDFLAKCPFSDEQQSTAFQSLPIKQATLQLLRFNCPFSSLHSLTEPGSSPPRGAPPTPCSFVASRGFIELARHTREQHGRLLCELCVKSKKIFAHEHVLYTPRQLVVHLPNLSTVPIDMQRGRGRRGRGRGRGGLSRGAGPAATRDVDMDNGADGEAEEEEEDMVEWSHPMCAFCRECFASSDELYAHLKEKHEECFICRNAGERDVYFLNYESLQRHFQSAHYPCPHPNCISQHFVVFPSDMDLKAHYVETHGGEMSQRELREMRELVNMFDSVPGASSVSTSSNAGQGRGGRRGRFGAQLTTAGLDGMGTPAQEDSDQAREALERQPLTDAQVTAWQALLNPLPVLPPTQLLALRSSLLAWLSHQQSAKDLLTILISLLHNPTSPTLSRAGDPDELVIKALQGLANRGKLGTDEEQELRTAINGFRAERAGAFPSLSRDSGFSAVASGRGIAVPLPLGGGGRAGPASTGRRGAPHRTVWDRVESAAQRTVPPPVALSAVPGRQQTSAQAFPALSASLAAPAPRRPGATAWSASASGSSSASPRPAPAPPPPPSVQAHSIPARSFTTTPSSVPNTPSATPRRPPPQADGRQFPGLPTREVIKVPLGAKGGNSSLRNILGQQDSSSSWGKPAGGSSWGRPLGSGSGPSSPTEATAPDGMEDGVASGGGNAPAAAGANTNGGGKKKRKGKETLFTLGSFPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSH2</accession>
    <name>M5FSH2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_83878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625027.1">
        <property type="nucleotide sequence ID" value="XM_040776645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSH2"/>
    <dbReference type="STRING" id="1858805.M5FSH2"/>
    <dbReference type="GeneID" id="63691707"/>
    <dbReference type="HOGENOM" id="CLU_004790_4_1_1"/>
    <dbReference type="OMA" id="RMGRFWT"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="595"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="634" mass="70150" checksum="376F88254BE72465" modified="2013-05-29" version="1">MARRPSASIADGEVEEIPLLANKSTTSFALKVGEAHTSITLVEDERSDYLHGARDGWEPYPTEEERSGPHRLRRVGRKISWPAYLIAFVELCERFSYTGTAAVFTNFLQRPLPPGSTSGANPAGTPGALGLGTNVAAAITQFNTLWVYVLPLVGAYIADTRLGRFKTVCWCVAIALFGHALMILPSLPSIIPHRSLALPIFICSLLIMGLGTGGFKSNISPLVAEQQRGPQRLTVERDEEGERVILDPSITTARIYMYFYLMINVGAALGQLCMTFAEKYVGFWAAFSLPTIMFCLCPIVLWWGSSFYTKSPPQGSNLLHTLRVLALAFRPLLTLSPTRFLRAWTDPDFWERAKPSYVAHFGRTGRVAWDEAFVEEVRKVASACAVFVWYPFYWISFNEMYNNMTSQAATLTTHGIPNDVINNINPIALLFLIPIFDKYLYPFLRRRGYNFSPLKRMFAGFISVGSAMIWAGILQCYIYTASPCGYRANDPNCEPAGISVWWQTGAYVLIAVSEIFASITGLEYAFTKAPKSMKSLIMALFLSTSAFASLLGECLNPLAGDPLLIWNYAVCAGMSLGAGAGFWWTFRALDAQEEKDELGGRKDLEDEDGENDDRDDAGGVDVHGEALTLQREGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSQ1</accession>
    <name>M5FSQ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625152.1">
        <property type="nucleotide sequence ID" value="XM_040773810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSQ1"/>
    <dbReference type="GeneID" id="63688872"/>
    <dbReference type="HOGENOM" id="CLU_1492504_0_0_1"/>
    <dbReference type="OMA" id="MNYQQMN"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="181" mass="20870" checksum="F1F348AB747D61CD" modified="2013-05-29" version="1" fragment="single">MLLQLQQAQLQQQQQPQQQPQQQAMVNGRPGLPMVTEEQRQAYLRMLIQAQTAQAQAQAQVQARNQASNQGLQQPQQQITQPGQPQPMPHQTPQQQVMQQQAMQRTTMQAQVQPQQLAPQQQPQLPQQQPQLSQQQPQLQQQGQRSRIIQQMQQILRMPAPPPGTNPEQWQQQKQWAQQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSW7</accession>
    <name>M5FSW7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625297.1">
        <property type="nucleotide sequence ID" value="XM_040773689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSW7"/>
    <dbReference type="GeneID" id="63688751"/>
    <dbReference type="HOGENOM" id="CLU_1578480_0_0_1"/>
    <dbReference type="OrthoDB" id="10449165at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="169" mass="18837" checksum="476F7C218F196586" modified="2013-05-29" version="1">MYPSRSAIPPYCTFLQARLQMVRDDWTQKTTPGSQFLSSLSILSNALRLSALFLALSLLSGMIHAVPGVLPLLRSISVLQLLATFAHAFLSRWIHHKTSERTLLSLSFLAVYGTLAFLLQQALVFLPIEPRLALLVEVVRWQGWHVVLDVADITPPKESCARPSLLVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT07</accession>
    <name>M5FT07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627573.1">
        <property type="nucleotide sequence ID" value="XM_040770323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT07"/>
    <dbReference type="GeneID" id="63685385"/>
    <dbReference type="HOGENOM" id="CLU_457094_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="47"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="597" mass="67010" checksum="3FE58ECEB01B4CB7" modified="2013-05-29" version="1">MSHRNPPESSNNRATNTNPEATASSALPHPGKTSIDLQSPFDKLSAEIVLAIFEHCLSDTPDVERKNQLCNIALVCRRFQALPYTNSSLWRSIELQVGYCWVFKGCGEGIWFLESGLQMHDHDEAVVTADASEGSVASLNDNDASTYGTLPSDDFPDEDALAELVEQAVSLSGDTTMVETTSHDVTHGAWTRSTLEHHLKHCGSEGTIRLHLNLTVLTESMNMRDAMFDQLRDLIDYWHRVRALRMNIDDWAIGPLEISNYINGELPLWSLSVQDFLRHSERIVVRVVDAVQLHTIKLAPASIQLVTVESKPVNLSGLEKVALMDAELFCISAEAHGKHAEAPRKIMSPIERTRFSLACVSSVQHLVLQKSNIVEGMQAVEFLRLQSLKINDHPLQILYLVRALNMPYMQKCFLLFPNCISFQYDDVDLDVQEASLIHLANANGSSLRHLIIKHAYCTNDAWNSVLTRLRGIESLALFAGALDNKFIDLFRSGGTLPALKDLTLDACIPFFHPRADPFNGNHFYPFSAKRIASMANQRSGERNGLISIRFALGWPRELSKKIKQVLMETVQSRDLTLSSWINPCPKLEELERDMKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT11</accession>
    <name>M5FT11_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_96355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626016.1">
        <property type="nucleotide sequence ID" value="XM_040777363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT11"/>
    <dbReference type="GeneID" id="63692425"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="ESFICAM"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="35"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="529" mass="58738" checksum="B2D05E4AC1D80F98" modified="2013-05-29" version="1">MAGGAAISTGGSAANQLLHQEVWWKNPRRVKLNLWILLLLITSYSNGYDGSMMNGLQILIQGQESFNYPNGSMLGLLNAIQNVGSLCATPFAPYVSDGIGRRYAVIWGASLMVIGCVVQTASQTVGMFIGARFLLGFGLTFAANAAPMLVSELAYPDQRAQLTSAYNSLWYSGSIVAAWTTFGTFTMTGTSWSWRIPSAIQAIPSVLQVLFMWWCPESPRYLMRKGREEEALRVLAHYHARGNENDPLVQFEFNEIREAIELDARVAQQVGWRTLFSTPGNRRRLRIFLALAFFSQWAGNGLVSYYLNKVLNSIGITNGTIQNLINGILQIYNLVVALVASSLVDRAGRRLLFLLSNSGILVFFTLQTIGIARYNTDGSSAAGNAVIAFIFLFYGFYDLAYTPLIVSYTVEILPYQLRAKGFTLFNFMVSLALIFNQYVNPVALDAIGWKYYIVYDCFLLFQLVYIWFFLVETKNRTLEETAAIFDGDSDVADLASRAAHDAHLDSPVPTSLSVDKTDKTVEIAMVEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT37</accession>
    <name>M5FT37_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_43541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625432.1">
        <property type="nucleotide sequence ID" value="XM_040774539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT37"/>
    <dbReference type="STRING" id="1858805.M5FT37"/>
    <dbReference type="GeneID" id="63689601"/>
    <dbReference type="HOGENOM" id="CLU_2782738_0_0_1"/>
    <dbReference type="OrthoDB" id="2273864at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="8060" checksum="25A5869F6D92D2E4" modified="2013-05-29" version="1" fragment="single">IRWLTTSGYHPCTKGKTEQYNGILELYLKKMNTTGDPTRWNEFLDTALFVTQVKQQTTAKWSPFELLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTM8</accession>
    <name>M5FTM8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_118547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625662.1">
        <property type="nucleotide sequence ID" value="XM_040770602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTM8"/>
    <dbReference type="GeneID" id="63685664"/>
    <dbReference type="HOGENOM" id="CLU_041818_0_0_1"/>
    <dbReference type="OMA" id="IWVELIS"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="413" mass="46620" checksum="A862561214D63843" modified="2013-05-29" version="1">MPYSHFPEDEASLWYEANFPVSGGIAQLHPGRQTILLLPYIGLDIASLVNQFQDPILSTTYNLLAVDFWSQGKTVNPTSERHDCWVDAASLLKVLARLQIQQIHVFAGGALSIGTALRLALLWPTGIQSLAVLSVHKPVEQWLVDTFKEIIITLGTAKSLEEIEDIINELFPYLFYDGLPDDELDFFAAYITRQYPPSRISRFNDMLYDFLTQWLSPLTSEHYSLIRQPVLIISPEDTMTSSREEAEDLKKLLINSVDPRLKIIDTPGTASYYTRCSYPKVNQLYTSFLRELSPRTCYSKNIPNMQAALRTLAKLTGNTNIQDRDPQKAFSFSCVSAEDVAEEHTTREQLDMLGQMAVNPVDPAAELPRKFSERHNQNFFGKHRTESNGEWLYAAIDVRVGQGEHVGSDSGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU44</accession>
    <name>M5FU44_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nonribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625912.1">
        <property type="nucleotide sequence ID" value="XM_040773548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU44"/>
    <dbReference type="STRING" id="1858805.M5FU44"/>
    <dbReference type="GeneID" id="63688610"/>
    <dbReference type="HOGENOM" id="CLU_000022_2_12_1"/>
    <dbReference type="OMA" id="CRIVNTY"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="88"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="614" mass="66657" checksum="66E39B12B6B92D81" modified="2013-05-29" version="1">MQAISLSGSPEAAFSLLLSPSQSCAPAPSCPDPSTSLPSPPAPPVYPPASRVNAHSISNLPVDDQTLFEEYGLAPARPAAQPFVHRAFEAHAARAPEVVAVEHASAGQQITYGELELRANRLARRLRARGVRPGKRVVILCRRSISYVLAILAALKAGGQYVPLDAQSITDEMLAHVLSDCAPQMVLCMQQYSQREPMLADIVRGKVMVVEEVMEEDERLQADGSKVRDLSKRDDGVYLIYTSGTTGVPKGVDVRHRGVGNVVSGHPGNVGMKPGMRVAQLLNIAFDMCAWEVLGSMYNGCTLCLRGDRYADWVAVLRTVHVVISTPSILLRHDPAHYPTLKHVIVGGEPCPQSLADRWAAFTEFNNCCGPTEISIANTVQKHTPGYPLSIGRPIPNTNVYVLGRDPSDTTPARIGEIGCMWVGGVGVSRGYLNLADKTAERLCPDPFVRWDGHGPRPMMFNTHDLGRWRPDGQLDHCGRADDQVKIRGFRVELDGVATAMSTHPLVSTAVALKLGEQLWGFYAPASVPSKEVRQATAQKLPDYAVPSQWLALDKLPLTPRGKVDKHVLRNMARPEMPSSQSLPDLRAVKREVAVNPMGSPALSDSSYGSPIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU82</accession>
    <name>M5FU82_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_82194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626641.1">
        <property type="nucleotide sequence ID" value="XM_040776555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU82"/>
    <dbReference type="GeneID" id="63691617"/>
    <dbReference type="HOGENOM" id="CLU_026673_29_2_1"/>
    <dbReference type="OMA" id="TGITAYW"/>
    <dbReference type="OrthoDB" id="809632at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF42">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="348" mass="37833" checksum="16CD275C1E0AFBAB" modified="2013-05-29" version="1">MAPTPTTYKRVVLSSRPSPTKLLDPAVFSLRHEPFPSPPGNGELLIKVLYLSLDPAMRSWINPSGSYMAPVPLGGTMRSFGLGVIISSDEGCKLKKGDRVQGFFGWTEYALSPEKAATLLAPPPPGAELLDYLGPLGPTGLTAYFGLTDIGQLKKGETLVVTGAAGATGSIVCQLGKLWGAKVFGIAGGTEKCQWLERECGVEMAFDYKTEGWREEFKRVAGRFDVLFDNVGGKMLDFLLTRMNKRARIAVCGGISDYNSRPKGLTNYLALINARARMEGFLIMDYAPRFAEGTRELARMLSRGELRRKFHVLKGVESAPEGLGMLFSGQNTGKLVVQVGEETERGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUW9</accession>
    <name>M5FUW9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623974.1">
        <property type="nucleotide sequence ID" value="XM_040770823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUW9"/>
    <dbReference type="GeneID" id="63685885"/>
    <dbReference type="HOGENOM" id="CLU_1777370_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16475" checksum="1933B3B0567B29B1" modified="2013-05-29" version="1">MGRKHGSSSKATRRTRRHACQEDRADPEARTDAGLPVGAPKETREEEVWDDGNESGSGEEDESESEEEEEDKCNTVYELQGEYLHDPDDEGETHTEVCKHFRVCKTIKTKAAELILVCYGKGKRGIDCHHWETYLDMLEGRGGESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVC8</accession>
    <name>M5FVC8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_88863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628643.1">
        <property type="nucleotide sequence ID" value="XM_040776879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVC8"/>
    <dbReference type="GeneID" id="63691941"/>
    <dbReference type="HOGENOM" id="CLU_2831149_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="66" mass="7608" checksum="32FA3BCA6C1031E8" modified="2013-05-29" version="1">MANPRHGNTVHEVTLLQQEYYALDLRFWRFEMSAIEWDPGTLASAQCMDEGNPMVRLFQVSGCQNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVN4</accession>
    <name>M5FVN4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Got1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_25167</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624309.1">
        <property type="nucleotide sequence ID" value="XM_040774040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVN4"/>
    <dbReference type="STRING" id="1858805.M5FVN4"/>
    <dbReference type="GeneID" id="63689102"/>
    <dbReference type="HOGENOM" id="CLU_124519_1_0_1"/>
    <dbReference type="OMA" id="MWLTDAQ"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000137">
        <property type="term" value="C:Golgi cis cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15404" checksum="E815BA614D4E29E8" modified="2013-05-29" version="1">MWLTDAQKIGVGLTSFGAFFLLLGVVLFFDGALLALGNVLFICGLTLIIGPKKTFYFFARRQKLRGTICFLGGIVLVFIKWPFVGMLVETLGFLNLFGDFFPVILTFLRQLPFIGNFLSMPFVSHILDRLVGSRPSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVS0</accession>
    <name>M5FVS0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_116350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
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        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
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            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
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    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU01936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770187.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63685249"/>
    <dbReference type="HOGENOM" id="CLU_125051_1_0_1"/>
    <dbReference type="OMA" id="NGKQWHD"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="130" mass="14751" checksum="D1512CB2942E5735" modified="2013-05-29" version="1">MEAEASTSAIVPQDTDTAIPLRASAGGRESGKLWKSTRAATRRTQMPKSLKSKSWEARVAERTQEEATRKIAKEMRDEKQAEADRKREVLRERRKVKEEKARLEAMAAKLSAKKLARMKKRAGRSKTVQQ</sequence>
</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
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                <person name="Martinez A.T."/>
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                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
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                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
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                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
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                <person name="Nagy L.G."/>
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                <person name="Patyshakuliyeva A."/>
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                <person name="Sabat G."/>
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                <person name="St John F."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
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            <begin position="75"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="EJU00594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="9263" checksum="8CD4848BEF9B2B9F" modified="2013-05-29" version="1">MARVISLDREAQRKADLARQESAPSVSSGLPSPHISTPNPFEETIRFESPAPMNGLVRSASQIERLGPKRMDTTSSSYSRSSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWP2</accession>
    <name>M5FWP2_DACPD</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
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                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
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                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
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                <person name="Larrondo L.F."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
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                <person name="Wiebenga A."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
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        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11409" checksum="FE17AED20F1965A1" modified="2013-05-29" version="1" fragment="single">ACPASFSPWLMTHSHPSLVRCTIPLAVCSLTTPSSQLNTTLHPPPSRPSTSTPNTSANITPLLPLIGCANVPSWGTHPPSTSDAANRTCLRFDSAKLFLPSVDCRCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXS6</accession>
    <name>M5FXS6_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">C-CAP/cofactor C-like domain-containing protein</fullName>
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        <name evidence="5" type="ORF">DACRYDRAFT_116494</name>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628201.1">
        <property type="nucleotide sequence ID" value="XM_040770214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXS6"/>
    <dbReference type="STRING" id="1858805.M5FXS6"/>
    <dbReference type="GeneID" id="63685276"/>
    <dbReference type="HOGENOM" id="CLU_032612_0_0_1"/>
    <dbReference type="OMA" id="YFQHEIT"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="116"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="33499" checksum="5B68CEB5504B7A36" modified="2013-05-29" version="1">MAEQRILGEQFVAQFKERRSNIESLAESGKGTPGEYESQVTALRAELTASMDLLTGYNQRQLDTQLKALEQKVREAKASAKPQGKFSFKRMKPVAKPVVASSSSSTSAPATSSLVPSTSSGHTIFSLSNSCITFASLNSEPGADLLLSSLDHCLVNLIPASADLPPPTPVLGSIHARALRHTVLLLPVIPGSVFLEGCTECLVVVGCHQLRIHASENTTVLLQVNSVPIIEHCRGISVGEYPAVLRALVLQDSGTTFDSKHAEMQDFNWLQGGQSPNWNRISAESATSWDDRVRRLMQQAQGPIADTVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYE2</accession>
    <name>M5FYE2_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623440.1">
        <property type="nucleotide sequence ID" value="XM_040774246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYE2"/>
    <dbReference type="GeneID" id="63689308"/>
    <dbReference type="HOGENOM" id="CLU_2687792_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="7978" checksum="99E042C42FE1D452" modified="2013-05-29" version="1">MAAYARAIGRADNLSVTRSGSISGRSQDGATARPETPREEKEKEKHESTDAESPQTVMLEASVASETKDKKDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYE5</accession>
    <name>M5FYE5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625469.1">
        <property type="nucleotide sequence ID" value="XM_040773592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYE5"/>
    <dbReference type="STRING" id="1858805.M5FYE5"/>
    <dbReference type="GeneID" id="63688654"/>
    <dbReference type="HOGENOM" id="CLU_010194_12_0_1"/>
    <dbReference type="OMA" id="LETMFFM"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_7G04540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="301" mass="31780" checksum="5A607F36C7F57699" modified="2013-05-29" version="1">MSSTPEEFSVANLFNLKGKIALVTGGGTGIGLMISQGLAANGAIVYVGSRRKEVVEKVSGPFGAGEIRPLVLDVTDKESILSAVAFFERAHSKLDFLVNNAGQVGPTSDWFTELSAPEQKEVGNNLFKDQSLEAWASHWQANVGSIFFVTTAFLELLKKAYIPGQGDGYVERWSPSVVNITSISGIMKLAQDHFCYNAAKAAANHLTLMLSTELALRRVLVRVNAIAPGVYGSEMTSGHTNGHFTAAAANAVGKGLTPLPSARGGTDREIAGTVLYLVSPSGFYTNGQIIAVDGGFVATNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYL4</accession>
    <name>M5FYL4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_22677</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628506.1">
        <property type="nucleotide sequence ID" value="XM_040772920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYL4"/>
    <dbReference type="STRING" id="1858805.M5FYL4"/>
    <dbReference type="GeneID" id="63687982"/>
    <dbReference type="HOGENOM" id="CLU_023810_7_0_1"/>
    <dbReference type="OMA" id="CFIAVGT"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000032">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000193">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500133">
        <property type="entry name" value="UDPglc_DH_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="336"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="93"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="280"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="471" mass="51460" checksum="8CAF6332740119E9" modified="2013-05-29" version="1">MAPVKVTKICCIGAGYVGGPTCAVIALKCPEIQVTIVDLNKARVDAWNSDDFDLPIYEPGLEEVVRQCRGRNLFFSTDVDKGILEADLIFVSVNTPTKKSGVGAGFAADLNYVELATRRIAAVATSSKIVVEKSTVPCRTAESMRTILEANSKPGCRFDILSNPEFLAEGTAITDLFSPDRVLIGSLQTKEGKDACRSLTDVYAHWVPIERIVTVGLWSSELSKLAANAMLAQRISSINALSAICEATGANIDEVANAVGKDSRVGPKFLRASVGFGGSCFQKDILNLVYLSESLHLPEVAAYWRQVVEMNEYQKGRFSKRVVDTLFNTITGKKIAILGFAFKADTGDTRESAAITLIKNFQAERALVTIYDPQVLHSQIWSDLMEASSGVPLETIKRQVSIASSALEACRDAEAVVIATEWKEFRTINWEGVYSHMTKPAFIFDGRLLLDAEKLRDIGFKVTVIGRGERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZC1</accession>
    <name>M5FZC1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628102.1">
        <property type="nucleotide sequence ID" value="XM_040773029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZC1"/>
    <dbReference type="GeneID" id="63688091"/>
    <dbReference type="HOGENOM" id="CLU_030671_1_0_1"/>
    <dbReference type="OMA" id="SLKHFAH"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="36209" checksum="7EC4E581B6BC31D9" modified="2013-05-29" version="1">MPLPESLPDWDDLPPVPGMPEGTAWPVWGPDDQLGALNLLTSENTLLAIQEVKSGKRVQLDWSLDKPKWPSFDRRQFGHRVMFKPGSAQDEVHYNTQSSTQWDGFKHIADPGTREFYQGLPMDDVISEKDTLRNGIHHWVEAGGIAGRGVLLDWYRWHALTRPGVPHPVPVTSHGIPVSELDAVAAFQHTELRRGDILIVRSGFTKWYNEAEEEARMRGVAHNGFHFIGVRPGRETKMWIWNHHFAAVAGDTVAFEQFPITDRSQCLHNYLLPLAGIPIGELFNLEELAKACEEEARWSFFFTSAPLNVPGGVASSPNAIAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZE0</accession>
    <name>M5FZE0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival Motor Neuron Gemin2-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625834.1">
        <property type="nucleotide sequence ID" value="XM_040770548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZE0"/>
    <dbReference type="STRING" id="1858805.M5FZE0"/>
    <dbReference type="GeneID" id="63685610"/>
    <dbReference type="HOGENOM" id="CLU_1065679_0_0_1"/>
    <dbReference type="OMA" id="WMEDPAK"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="261" mass="28748" checksum="852BE41AC542B497" modified="2013-05-29" version="1">MDPRARKVVSYADISPSIPDEAASITDPASNARPAKRPRISDPPIPSSSTPLNFTGKALNGQPKKKQKKDPKSWQTSRTLTHEEIWDDSALINAWDAAMEEYRAINGEDKGWMEDPAKQSALWWNTQPSEEELPIEEEGEDEYPEDGVEADADIEETDAELLISTIDIPTAPTTYPTMSSAQVASPVLPFPSTSSTSILEQLPEDPEKVLELAVQSYYWAGYLMGRRDELLRRRPAAPVEAVKASKPDQEAGGEVANAEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZE4</accession>
    <name>M5FZE4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPIN90/Ldb17 leucine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628132.1">
        <property type="nucleotide sequence ID" value="XM_040770202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZE4"/>
    <dbReference type="STRING" id="1858805.M5FZE4"/>
    <dbReference type="GeneID" id="63685264"/>
    <dbReference type="HOGENOM" id="CLU_017272_1_1_1"/>
    <dbReference type="OMA" id="ERMCEII"/>
    <dbReference type="OrthoDB" id="445362at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="2">
        <location>
            <begin position="196"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="590" mass="66272" checksum="DBAB4F1D6EE508B8" modified="2013-05-29" version="1">MDFVVYHIRNAAQFWSELEDCLKLQPDATLDQLDSALETFVSICSSYHQEYLPTKMQMDQAVRMLLSSELFAFHSERESERVLSEARTCTNPHTQLILFHILLHHGRTHPSFFRSVSKWQTLIPLLMDHLLVDCDVVVPFTSAGGWVEERMRVLSVKVLYEVCRVQKMGLNDLRMFDNAFIDHLFDLIEHTRTFPDEDLNYSLIKLIVALNEQFMVASIPNPQHHHHHLHDPQGQPSPPNSANSLHIPDTGSTKVPQNRVLEVLVRRLGSTKTFGENMIFMLNRADGSAEALCMQLLILKMLYLLFTTRGTQEYFYTNDLCVLVDVFIRELNDLPEESESLRHTYLRVLDPLLTNTQLRLVPYKRLEIRRILQAHLANAHIRVINPTTKRLVERCLSAPWAGNHGPEEDSRSISSTGSGSSPASPVSAHRAGAAVDSLVPSLASLHLPKNDNKSTTSVNAVAAASPVTTSPKTRPRRASRSLSDPSIPPVVTPEFTRHHPPVPHLPAKLRHEHPVRKASALPVPHDRIRGGSAPSTPPLKKRKPPAIPDRSHKYKYTTPPTISVAEFGVPVEAECLPVPAKSRGRGTVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZS5</accession>
    <name>M5FZS5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_102688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623910.1">
        <property type="nucleotide sequence ID" value="XM_040767655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZS5"/>
    <dbReference type="STRING" id="1858805.M5FZS5"/>
    <dbReference type="GeneID" id="63682717"/>
    <dbReference type="HOGENOM" id="CLU_1255956_0_0_1"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="25253" checksum="C1FE8764E33032BF" modified="2013-05-29" version="1">MLNILVIHGYLQTAATLRYNILPLERELSRIANLHYVDGPPMQDLSWRDSRPWWVIKSGESWLDPDNTTNRWDETVRWWSEHLSENEYDGIIGLSQGSAMTALLLSMLNNADNVPEFEPKKSQPIKFAILCSGFVSQHHPHRNIYDIPLHIPTLHTFDNRDMRVSAHRTIELSSLFGSKAVRKSHNEGHAVPVRDAWPKVFSEFIAGAVEESRMRQTDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G032</accession>
    <name>M5G032_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_18867</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624030.1">
        <property type="nucleotide sequence ID" value="XM_040771401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G032"/>
    <dbReference type="STRING" id="1858805.M5G032"/>
    <dbReference type="GeneID" id="63686463"/>
    <dbReference type="HOGENOM" id="CLU_005034_1_0_1"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="889"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="11">
        <location>
            <begin position="689"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="920" mass="98139" checksum="0900F7776002D0E9" modified="2013-05-29" version="1">MGNVGCAISWAEDSLFVLHENRVFSISHTVDWTFTPEGETLFLQMLTTESHVHLLGLDTAHAKAQPVHVVLSHSGALLQRTVLPALAPLHNDPDPVLLYPGVVAHLSQGGLISLPLPPSSKPHPLPGKYAQLIPLPPTPGLVVGVKEDGSACVLATQEGGLTEMWEYADSARSAMYTESVFAGAVDRLGGRHIARVYWTHTFGRADWIGLDWIGWDAKLASIHLWSEMGPGGKGGGMVSGFTFPFDTKSHGVICTITLEVAFSPSQPQPQKPIPRFLITTSTGSIQLWQADQLQWTREEGLAELVGGVGWADRGLAAPGGLGLGLGLGGGGSAMGLGERGVGDAPEGLGEKWARQLGSIWKLPGYGISFLLRFTDSLSLFPPSASFQQSALNKLALVASSSGKLYALETAPSAPGAPGGVLWSQILGVSGAPGGMGRVDVQRILSVAGVGWVVLGRRWDEHGFKTAAWSIDPLTGTIYPPPGREGTTPGLTLFPGPMAEAFVLPPSPSPSPQSTSHNETVVIVSQSGEVYLFPTDEARKAALASRSREGVFFSLPLHTGDVSSSQAALQGFTLLPSPDADGFASVPTYRTFLTPSPKSELLGLIRPPRGPVASLGRVLGTKQTLYKYLNPHLVVALTQYPVEGEGEQEGEIEIRCGIHLVDQISGSIIYSASVRKPRGRACDVKPVLADNWLVWVFWNDGDSGVSLGKGKGEGEGEGGRTKGWRVVVVELYEGEPDEITRSAQLSGFASNSSRVHGISQTYGVPSAWKAVTTTLTKYGITLKDVVVANDRGQIQAYPHALLDPRRPSGKLTSEQKEELLIPFDSVITDDPRRTVSQNLHIMGISSLSTTPTALESTSLLLASGLDIFLARLSPSSTFDILGENFNKTQLILTVLGLLVAIVIVKPIVESKKVRQRWYTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G055</accession>
    <name>M5G055_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_102553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624060.1">
        <property type="nucleotide sequence ID" value="XM_040767640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G055"/>
    <dbReference type="STRING" id="1858805.M5G055"/>
    <dbReference type="GeneID" id="63682702"/>
    <dbReference type="HOGENOM" id="CLU_370888_0_0_1"/>
    <dbReference type="OMA" id="WQDQLLD"/>
    <dbReference type="OrthoDB" id="3358141at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037508">
        <property type="entry name" value="Msb1/Mug8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012965">
        <property type="entry name" value="Msb1/Mug8_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093:SF1">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08101">
        <property type="entry name" value="Msb1-Mug8_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="119"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="750" mass="81941" checksum="295AC30B903EAE69" modified="2013-05-29" version="1">MSSFITRIQRSFLKKRDGQIDSTGLQSPTAPEKPGKVPVKPLTKAFVSPSPAKRDAPNSPHSPRRPTSPILPFLNKSSSKKHLNSPRSVEPIPQLSLTLPDPSPVSHQADPFIPDIARTVLDKQVLDEKRLKLEEALKMLQTAGGVVMERGLETLGIFRPHWHSENFEVQQALLSMFIASLSSGQDGAGTAAQEAFLTELRYTSDVHDVTSVLKWALRHLHFEDGPFGLTTGNALEGQPEWSWYRTFGLSEQQANYPLSAFTLLLLPSLPPGHADLLRSLMDLISSVASHVAQNAMSGNRLSKALALWVVAPNISNCTSFGAFYEQWQRASRVMEHLFLCYVRDVGRAHKLPARLAELVAHYPFNNVPASTDMFLPQPDLTTHQFKALLVRIKQTSPSGRTDMSELLPSELLHHALIAKNDPSSSHSAELEDLWSLLKAKATPAMENMNGIVLPFDLSRLIAEESLRLMSLPTQSSTTSPTPLSQSTVDPERSSSGRSKRRSFSMDHGRSKPAYSSLTVLYEDSSPITRIRSQENLSAPASENKVDWDSFSSSGFGVLSSTTGLAESLSGRTVNGSARANGTTESTDKKNVLRQEPPVDIMPPYLAALSLVPLDEAFIDVWCDSLLDPTVRQHWPGYVLCQLSDSAKAAGACVGAEWLVIEREIVSSPGPVKTQSIQRSPSNVSAATTTRFNRSLGRAAAEVTSRKRFSLFSTSSGRSVRGRKESSATIASKHAPIDELVDAPPLPSQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0J8</accession>
    <name>M5G0J8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624225.1">
        <property type="nucleotide sequence ID" value="XM_040774019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0J8"/>
    <dbReference type="GeneID" id="63689081"/>
    <dbReference type="HOGENOM" id="CLU_372550_0_0_1"/>
    <dbReference type="OrthoDB" id="3349657at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="651"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="746" mass="81716" checksum="99E06A7D8D7A22C1" modified="2013-05-29" version="1">MEANSTAVMSQVRVVDENESQDVLHMPQLPTQGAHTPSHSITKSPENMAFLSDSNAPQTGKSTANQYARNELDSSEDGEIEEQVRPVNTPRRRIHLGNNWWGSMSEGLEREGAKINGVISIPIPFTGRFLRFKIFRWWFSFNGLVMIGILILYTILGLFAWNSTRADHNNIFVLPSTDSIFVISTLSTAGTTLISMLVGSALESVRWRKAVNGVYMATFLGLSGATGTQGKLALLRSPHIVWSTKVWVLIVFAFAAVNYLLSNILTVGLSSATVFQVTHWEFNTMSGIGPWIPHDLTSILYPTSMNMSIRIDHTYDSFTSDSTQVIQLTTNVTRFPGSHIIPTAFRTLCDDGCFAYLLPGTVSQVITPGPQPPIGQTYCSTASPEECVTPPFVVDVGGLPSLLACQPGDMLCIANAILDDRKSPNRSSYATMNTNLTSWPNFAVSDTLRTHGPAAMVYFEPFTFDGPAEASNMTGCQLMTALPYAINICYKHIDQSSFAIGWATCDPVLHNCTFSDTTWRESLTSSTIMSLEQRQVGVVHYLPTGTLNGIEDFEDASLLTINSTQFFNVITSVFDQGTAMSNLIYNAANSPNLAHFGADLRMRDLLTCTYSLGASQIQVDAPLGSNVSWNNAGQAGINIATDRIIMSLTSIIVFATFAGLTLVLCALMFAYSSSLITPNNTDFSELDIASRAAHLRIFDGLSNADNKEVVERIGQERIWLGESKDGRSIEMATERLPPLQLHKVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0P5</accession>
    <name>M5G0P5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_49077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630720.1">
        <property type="nucleotide sequence ID" value="XM_040774880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0P5"/>
    <dbReference type="STRING" id="1858805.M5G0P5"/>
    <dbReference type="GeneID" id="63689942"/>
    <dbReference type="HOGENOM" id="CLU_031040_8_1_1"/>
    <dbReference type="OMA" id="YDETTDW"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.20:FF:000009">
        <property type="entry name" value="Peptide-methionine (R)-S-oxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="7">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="16545" checksum="BB1DFA51C8483639" modified="2013-05-29" version="1">MQKDDAEWRAILNKEQFRILRQKGTEMPNTGKYNHHSNAGIYTCAGCGTPLYKSTTKFDSGCGWPAFFDAIPGAVVRHEDRSLGMTRTEITCAACGGHLGHVFKGEGYNTPTDERHCVNSVSLDFTKDEEWRKKQEEEGKENGRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Z1</accession>
    <name>M5G0Z1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_102497</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624350.1">
        <property type="nucleotide sequence ID" value="XM_040767638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Z1"/>
    <dbReference type="STRING" id="1858805.M5G0Z1"/>
    <dbReference type="GeneID" id="63682700"/>
    <dbReference type="HOGENOM" id="CLU_032441_1_1_1"/>
    <dbReference type="OMA" id="NAPTRRW"/>
    <dbReference type="OrthoDB" id="5566198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="264"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT97452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="44759" checksum="CC0DFF4ADD52F43B" modified="2013-05-29" version="1">MLQSALLPTSLFQDIITDLSYNYYGTSLAVASADHRVRIFSLSAEPSVSAAPGIGTGAGTAGGSSGGWELEDEFKAHDAPLTRVSFAHPAFGPLLATAAFDRTVKIFEDVPSRGAGQRSRWVERKVFTDQGASIRSLEWAPEALGLKLAGVGADGCVRIWECLDLPSLEVWETREELGMMGLFGEGVVGAGGEGVREGRLGGVGVGGERQAATGGWETDAGWALAWCAERWWGDVLAVCCANQGCVKIMQFPGGPARPVTLTTLVPPTPPTPVPLPAPLPRRKADHSHSPLPLPAAVEEPPRTPLTSVAWAPACGKSFHLLAAGSEAGCVYLWKVVPGKEGVQEEDSWKAELVGEFEEHGGRPVGRVQFNPTGTILSSAGDDGRIRLWKASFTGVWRAMGSVWATPGDEEEEEDEGEDGYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Q0</accession>
    <name>M5G1Q0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_106704</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629533.1">
        <property type="nucleotide sequence ID" value="XM_040768316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Q0"/>
    <dbReference type="STRING" id="1858805.M5G1Q0"/>
    <dbReference type="GeneID" id="63683378"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="DADYWID"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067500" evidence="15">
        <location>
            <begin position="28"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU02639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="56251" checksum="2855E49837EE0503" modified="2013-05-29" version="1">MFSLPQLAFGAGLLCLVFLYALRGPKGKLPPGPPGLPIVGNLLEIPTKQMFLKFDEWAKKYGDLYTVNVAGKKIVVLSSAKSSGDVLDRKSGATSGRPRFVMAGEIMCHNLLYMFMSPGEQWRRLRRVTHEGFNIRACQAYYPFQEQEAANLVRSIMAEPTDLGQKLKHATAAATWRSLYSGPSLTEEDEAKVCGIDNVGETVLGASMPMAFLVDVIPAMKMLPNWMAGWKAWGEEWFRESGRFFHGLLDDGKQQKKGVEHHVGFIASTAPSFKKFGVTEQEAAWTAGGLFIAGVETSGATLHYFIQAMVLNPEVCRAAQKHVDSVVGNRPPTFDDRDQLPYVVAVVKETIRWRPVAALGVPHVADEDLEYRGYVIPKGTQIIGNIWSIAHDPAYFPYPEQFQPSRFIDSSGNIKEPFPNYHDDIVAFGAGRRVCPGRDFANNMLFIDMAYLLWAFDFELARNEMGTSMPDTMKFDDHGLIILPVEFPCVVKPRRNDLGELLGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1S3</accession>
    <name>M5G1S3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartate aminotransferase</fullName>
            <ecNumber evidence="10">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_23409</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="10"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626734.1">
        <property type="nucleotide sequence ID" value="XM_040773227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1S3"/>
    <dbReference type="STRING" id="1858805.M5G1S3"/>
    <dbReference type="GeneID" id="63688289"/>
    <dbReference type="HOGENOM" id="CLU_032440_1_2_1"/>
    <dbReference type="OMA" id="VGACTIV"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006533">
        <property type="term" value="P:L-aspartate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000026">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000160">
        <property type="entry name" value="Similar to aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="50"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="46141" checksum="68403E8FC7BBD437" modified="2013-05-29" version="1">MLSRQLKPASTRLVRLAATRPVSVWSTVPQGPPDPILGVTEAFKADTNPRKINLGVGAYRDENGKPYILPSVQEAENRLHGQVDKEYLPITGLPSFTSAAAKLAYGADCAPLKEGSIAVTQSISGTGALRIGGAFLSRFYPTSKVVYLPSPSWGNHTPIFRDSALEVKTYRYFDKSTVGLDWAGMIQDIKEMPTGAIVLLHACAHNPTGVDPTKEQWEELSGLIKEKGLFPFFDMAYQGFASGDIAGDAFAPRHFVSQGHQIALCQSFAKNMGLYGERVGLFSLVTASPEEKARVESQLKILVRPMYSNPPVHGARLAGTILNDPALYAQWEGEVKGMASRIISMREALYTLLTNTYHTPGNWSHITSQIGMFSFTGLTQAQTEVLASKRSVYMTKDGRISMAGLNGGNVEYFAKSVDGAVKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1S7</accession>
    <name>M5G1S7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_25036</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624580.1">
        <property type="nucleotide sequence ID" value="XM_040773976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1S7"/>
    <dbReference type="STRING" id="1858805.M5G1S7"/>
    <dbReference type="GeneID" id="63689038"/>
    <dbReference type="HOGENOM" id="CLU_076902_12_3_1"/>
    <dbReference type="OMA" id="GYMNVQL"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000011">
        <property type="entry name" value="small nuclear ribonucleoprotein F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="12"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="89" mass="9853" checksum="0E7CE22867137129" modified="2013-05-29" version="1">MSSGPGPVTPVNPKPFIQDLTGKQVLVRLKWGFEYKGYLVSTDGFMNLQLANTEEFQDGKSNGALGEVFIRCNNVLYIREAPAEEVAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1V9</accession>
    <name>M5G1V9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_84776</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624630.1">
        <property type="nucleotide sequence ID" value="XM_040776699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1V9"/>
    <dbReference type="GeneID" id="63691761"/>
    <dbReference type="HOGENOM" id="CLU_001265_54_6_1"/>
    <dbReference type="OMA" id="LYGLCWP"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="487"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="546" mass="59146" checksum="CC19A7AAFE9F225E" modified="2013-05-29" version="1">MGTSKQQQSANVNIQTAPPSPLESTALLSHPKTRTPLPIAQLTLICIVRLAEPVASSQIFPYINDLCVEFGYAKTESDVGFISGLIEALFALVQLLTVALWGRLSDRIGRKPVVLIGLLGVTGATLLFGLSRSLWLTILARCLAGGLSGNSAVIQTMISEVTDESNESQAFPLYSLMWTLGSIVGPTFGGTLSRPAEQFPDTFSAPFWTQFPYFLPCLASAGTTGISIVTSLFLRETLPRKHTTPPSADRSPQLQPSYSTLPAPAPQPTAWQILRSPGIPTVFVTAFMMMLTTQAWDVVFPLFAFTSIRAGGLSLSDAQIGYLLASAGFVGACVHLFLFPAMERRFGIKMYPWLLAFPMGMYAYAPALNGWLRSRGGEHWKRGHVDVGTIVGAGGLLLMGRLAAMVYPLNMMLVKRAAPSRAGMGSTYGMSQMVTSFARTIGPWGVSSLFAFSAEHNLLGGNLIWLAMACVSAVAVVQSLRVERSLDGRAREVESESEAGRAEQDRERGTRFGRDGESDGGERDQENRGRGDIRQREIAWEHEEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Y1</accession>
    <name>M5G1Y1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADP-ribosylation factor 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_20799</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772088.1"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
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    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:GTPase activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
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    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000286">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arf6"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
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        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="182" mass="20761" checksum="D42A6A20BE06D6CB" modified="2013-05-29" version="1">MGGNLSKAMANLFGKKEMRLLMLGLDAAGKTTILYKLKLNQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLVFVVDSQDRERIDEARQELHRILADREMRDCLLLVFANKQDLPSAMSPAEVTEKLGLHRMRDRSWYVHPSCATTGEGLFEGLQWLSQNVKKKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G260</accession>
    <name>M5G260_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626864.1">
        <property type="nucleotide sequence ID" value="XM_040770414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G260"/>
    <dbReference type="STRING" id="1858805.M5G260"/>
    <dbReference type="GeneID" id="63685476"/>
    <dbReference type="HOGENOM" id="CLU_1175395_0_0_1"/>
    <dbReference type="OrthoDB" id="1112980at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062064">
        <property type="term" value="F:box C/D methylation guide snoRNP complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027921">
        <property type="entry name" value="NOPCHAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28674:SF1">
        <property type="entry name" value="NOP PROTEIN CHAPERONE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28674">
        <property type="entry name" value="SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15370">
        <property type="entry name" value="NOPCHAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="236" mass="25289" checksum="90114A608C53F861" modified="2013-05-29" version="1">MAPQNSTKKKLKTRSKAPRSVQLLEVEDDDARESRLGNLLEQKASEHLRSSSATKARSDSWNTQRELPLRLGRLNEPLPTMETTSNLISRLDAFLPSLKASNDALIDQAARDPNSIDIEHLTPTEEGMVPAHIEMNLGLGVFTVKRGGDASTAEDSNGEDNGEDDSDGEDGDEGTESDATSEVQSESSDGHGGSGEGANNSGAQLALSDQNEHSTPEMVRDADVAPPDVRYRPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2H7</accession>
    <name>M5G2H7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_90110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL40 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626959.1">
        <property type="nucleotide sequence ID" value="XM_040776946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2H7"/>
    <dbReference type="STRING" id="1858805.M5G2H7"/>
    <dbReference type="GeneID" id="63692008"/>
    <dbReference type="HOGENOM" id="CLU_090382_2_0_1"/>
    <dbReference type="OMA" id="ERAWFLH"/>
    <dbReference type="OrthoDB" id="2098203at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019192">
        <property type="entry name" value="Ribosomal_mL40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042831">
        <property type="entry name" value="Ribosomal_mL40_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09812">
        <property type="entry name" value="MRP-L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="21805" checksum="14B108428722E8E6" modified="2013-05-29" version="1">MFNVNVRVLPPRLVHTIPLLLRTYAAPARNVRDTSDPRVEIMKRALYPPTLDRKQDTSPTGLHRSDVNTLLDVAVPSAEAHETITRAWLLYQRQQRDARDADMGRKFDSMLAALDELKMCDEKLYRLAVYKPNMRKLSPEERDAMKGLKSSAARRAIEARNESLFPRELRIPTDTPSRKGWDHNWTPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2I4</accession>
    <name>M5G2I4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_101130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626964.1">
        <property type="nucleotide sequence ID" value="XM_040767524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2I4"/>
    <dbReference type="GeneID" id="63682586"/>
    <dbReference type="HOGENOM" id="CLU_076407_0_0_1"/>
    <dbReference type="OMA" id="FKIKWIN"/>
    <dbReference type="OrthoDB" id="5418203at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039884">
        <property type="entry name" value="R3HC1/R3HCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678:SF0">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678">
        <property type="entry name" value="GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="262" mass="26921" checksum="4069334AAD9FAE74" modified="2013-05-29" version="1">MSSAPVPGLPLPQNLSASVTRILHLSGFPPELKTRDIHSAFQVWENDKGGFKIKWIDDTSALVVFNDAVVAKRAYLQTLLTPPAVLVSPTSTLPLQIRPYDGPDAQAIIQNVNARTTGPPSRQNSQNAHQSRAPFSVSPAAGTGHIRAASMAAAIPSVGGHAMSSSMSLGQLGGSAASRWAPKGDGSTPPALPEIPYQAPLGAMINGSGSALATSPAVEEAPVQGGARIGDAGRRMVAGALGVRHPSLRRNSPPTGGSEITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2J7</accession>
    <name>M5G2J7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631340.1">
        <property type="nucleotide sequence ID" value="XM_040772174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2J7"/>
    <dbReference type="GeneID" id="63687236"/>
    <dbReference type="HOGENOM" id="CLU_2158264_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12396" checksum="23841F246CEC8F96" modified="2013-05-29" version="1">MLTISEIVCRRCFLADLFPDPSSPGTPDVHALSRTPTTEHFSPLVSRLTSQCASGYSLHNVDKYRFNPDSGYKAVQRVETAGSRALYEIKLYDRSPWVVSLLNSVSPTYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2R1</accession>
    <name>M5G2R1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU00132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627029.1">
        <property type="nucleotide sequence ID" value="XM_040768902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2R1"/>
    <dbReference type="GeneID" id="63683964"/>
    <dbReference type="HOGENOM" id="CLU_1384122_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="22003" checksum="5E45C49FA00E1F0B" modified="2013-05-29" version="1">MDAESRTAKELGDQLTANLEECAKRPELIWVARFFNPYAPVDGVVRLEPPPSTRFTTKLYNSAFIYQYALDRRRFTLDEARVLSLIELSKIQRDPGDYGISSKGPYDIDWALACEEPFPGIREAVDTDDDSGYESPAVPNGDNESESSTPDSGSNINGMALAYVMRSQPETMRAWVSQLGMILHIFECRPDPAANTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G307</accession>
    <name>M5G307_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_113996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
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        <location>
            <begin position="139"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="413" mass="46172" checksum="51A39A94246C1068" modified="2013-05-29" version="1">MTTYMYGKPSPSKDNRNQRGPPGTSMPITPATIARLRPARVFQKAVDPAPPSDPSAPHTITSLSFDNTGEFLVTAGEDEAFRLYNCRQGKLVKPFWSKKYGVDLATFTHKSTTILHASTKEDNTVRYHSLHDNRYLQYFKGHQRRVICIQMSPVDDTFLTSSLDKTVRLWDLRSPTCRGLLNLPRAPVVAYDNTGVVFAVALSSPPRIALYDASAWDTEPFLSVELNDTQLAQRAFPPRVPVVTSLQFSSNGKWLLVGTAGEVHYVLDSFNGDLLARLEGHQGLERGKHPGAAADIVPRRGISGQEVTFTPDSKFVISGSHTGRWHAWDLLNKEETMSGALVGKEQEVRTVLPSFGLEGHSAPVRCVRWNPRFAMMATAGEELAFWLPERKFEPPRREERERRPSGDVRMDGR</sequence>
</entry>
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    <accession>M5G3V4</accession>
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        <recommendedName>
            <fullName evidence="4">Arrestin C-terminal-like domain-containing protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_118718</name>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
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        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1153"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1194"/>
            <end position="1211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1211" mass="129332" checksum="75FDDC02B61EA59C" modified="2013-05-29" version="1">MSQIKIIVRQPPNRDFLEGFPGIPPNAPERPNAALRGTVELRVQGGTPVKAKWVQIELKKIETLLQGQGEPYVETIGHAPRIWQANGEYENLQVRDFPFYIQIPMNVPPSIALEKGSGIRYEMVASLCVKGKKGILRKDKNNVTSTSVPIVMDKHELHTLWPVYHRPQTSTATNDGLNLIVTRDASCYGPGDSVTARVELRSGRLSPCILRAWEMTLREHVIFRPDPSQLTHSKQAPVAGGQQYRHNVIAEQKKSLSKTIYEGVTVQDELACLIPIQHRTATTQGRLIEVQFTLSVKAVMESAGSVEVMMPVLMSHWSKEMSENSLRKIGPVPHLGIQFPPVPTAAAQPSQGYNQPQSYTQSHSNGSMQTLPQEVQPMRPQIAKNELPNPDDVGPPSPPYTPPEMGSHFTSQQANGRTANGRPRESTLNSRSRTLAVVNIDPNENGASPSPAVSSVPPSQPYKASWESAEIEKKRLKEAYSQEQGQSSSSSQQPIVTTTPSTPAVKPNFSSAEDEKERLYRRAQAQARRTQDLARKEQGLPPSVGSPSLSAISNQTSASASASGSTSNSSALRSPKVAPITAVASSATPLTPPATSSKAPSIRSESVTPGASPPPGSNWASAEAEKERLYRIAQRRARETQARVASATPAGGSASSPTPRQSIVQTPAASRPTSTFKLNNPDSPEDGPIQSGSSALTPARAASASPAPAPSITPGGTSAATAAQAMYAQAMAARQSPASGSRQSVGYTAASPQPTHGHTPRPSQASSTSYSQGSGSSLPPAYATGGSSGAGPGWSNAEDEKAQLSRYYEAKHAVSRKAEGGDIGEPMGAGGGSSSAYIHAHSASSLPLSQMTSPALAPQPIHQASPSPVGHYASSAPTRMNSVASVRKEQTPSPVYNRTHPQHTPTPSAGYGAPQDYFTQQRPYTPQQTAPGPSAFSPGSRASGVPLPVDEKERMKLFFEAQDAARRYQETQGASGSGGSGMNNSPPHAGPMASSSSYPSPPVTVGPPGYEDAPPAIDGGSSRSMSALEEKARLAREYQQQQQVAQGQLSRNPSIQSVRTPGPPQMPQYGAPPMLSPSYSNSGLPSITTQYGTTPLQRNNSSYKFIPSPIEEEPSGPPPPLLPRPPQAYIEQTIQEEAPADVAAEHGRPAVEKQQSWKNQPLNFRPMSPFNVPLPNAQNQPLVQGHWEQPPPTQQQYAQPQYQQAQPPYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4H0</accession>
    <name>M5G4H0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625535.1">
        <property type="nucleotide sequence ID" value="XM_040769073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4H0"/>
    <dbReference type="STRING" id="1858805.M5G4H0"/>
    <dbReference type="GeneID" id="63684135"/>
    <dbReference type="HOGENOM" id="CLU_026673_16_5_1"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="342" mass="36095" checksum="6A43E823E9366527" modified="2013-05-29" version="1">MALPFQALSLTSHKQTTPLTLLPFTEPELGTGELLIQNVAVAQNPVDWKQIDFDFNIPSLPFVPGADIAGVVYKVGPSVEGFKGGDRVISWLTRKTARHGGYQTYSIASHGRTFHLPECYSFEQGCTITAAFASAGAGLEHGLGVELPITPAKWPAESDGEPLLVWGGSSSVGAFVIQTAKAAGYTVFSTASPKNHAYVKSLGATEVFDYHDPDVVSKIRASVGPNLSKIFDSISENGSIEASVASITAPSGIVAVILAPKAEQSTATVRVVQTGALKTSEPEIGQRVFGLLNALLQNGSLVPNPIKIMPGGLLGVNEGLQLGREHRISGEKLVYVVADTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4K1</accession>
    <name>M5G4K1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630513.1">
        <property type="nucleotide sequence ID" value="XM_040771050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4K1"/>
    <dbReference type="GeneID" id="63686112"/>
    <dbReference type="HOGENOM" id="CLU_1081910_0_0_1"/>
    <dbReference type="OrthoDB" id="3358478at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="27769" checksum="A09C58560C774AC8" modified="2013-05-29" version="1">MTSSSTLPDNVSQAAFAGLLTAAGFFGIALIGLIVYVLGRWRREVKHKRQASTAQPYYLEDMPITLLSVRESVMKPPMYSSSPWAVDAEAQKVALSVLDMKSPALPGYSVPDSMAAELRASFASPSKAPILMVSSPWTPTTPGSTNPLGSSHLAQQIKVPPIPPPIPIPTRAAEREALARYTMPPPTPHCPITGMPLDITQRTPPPVYNASMERAQRAALRQQRRKGNQKTLWRETLKSVKSIKSAKTAVTASSSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4M5</accession>
    <name>M5G4M5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627704.1">
        <property type="nucleotide sequence ID" value="XM_040768750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4M5"/>
    <dbReference type="STRING" id="1858805.M5G4M5"/>
    <dbReference type="GeneID" id="63683812"/>
    <dbReference type="HOGENOM" id="CLU_598545_0_0_1"/>
    <dbReference type="OrthoDB" id="3237291at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="457" mass="49060" checksum="DFA393B8C7B5D6EE" modified="2013-05-29" version="1">MAGDKPLAERIAALQRKNTPPQSSPQKPNQLGLRRPSGDGLKDRIARFEAAGGMPVPKAGASFGLAAPVSSDRKTSRELIGNRIPSAGRFYLPRSRSASPTTDMDTSPSRSSSPEVLWNDIKGDLHGLVADGYGDRERVTFPASGPRPALENDGLPASLLHKSDNVVHLKHNEVPAILLSGPYDRSVASGILRDTEGPDKPTQDTELVTEGHELSSSDVDSPTTPRENPAEVQTSHNAILDGGPSLVSASINTPIMPDFSKPDHVGSDLQTGHSDSQLGCKLKKEEFGDSDRECSQDPVPTCHDTGVLSAMAPPIENACGEQACGSEDKKVIPPVPVLRATSVQVQLPTPPVEFPSINGVTNPSSPSRSPTKVGATLDLRTSSPTETTLERSISMETEIHNFILMCHGFSILLEGSDHWVYELQRSVIDRQTPISASITDLIVILMHYFRSEDLTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4S6</accession>
    <name>M5G4S6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">26S proteasome subunit P45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_21178</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772276.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G4S6"/>
    <dbReference type="GeneID" id="63687338"/>
    <dbReference type="HOGENOM" id="CLU_000688_2_2_1"/>
    <dbReference type="OMA" id="DHEPCVI"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000008">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000034">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="177"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="399" mass="44564" checksum="74824124B1DD4C34" modified="2013-05-29" version="1">MASGIAIAPPHFDERKIDSLKAYRAKMQEHENMSEGLKNLRFSLRDLEKDFQKTEDDIKALQSVGQIIGEVLKQLDADRFIVKASSGPRYVVSFRPTLPIHKLKPGTRVSLDMTTLTIMRILPREVDPMVYNMSLEDPGGASFAGIGGLSEQVRELREVIELPLMNPELFQRVGIKPPKGVLLYGPPGTGKTLLARAVAATMSTNFLKVVSSAIVDKYIGESARLVREMFGYAREHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGRTKLIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQGRLEILKIHAAGVNKGGEIDFDAVVKLSDGFNGADLRNVCTEAGMFALREDREYVTQEDFMKAARKVGEAKKHETKIEYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B7</accession>
    <name>M5G5B7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PI-PLC Y-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630763.1">
        <property type="nucleotide sequence ID" value="XM_040768185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B7"/>
    <dbReference type="STRING" id="1858805.M5G5B7"/>
    <dbReference type="GeneID" id="63683247"/>
    <dbReference type="HOGENOM" id="CLU_386849_0_0_1"/>
    <dbReference type="OrthoDB" id="284473at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032979">
        <property type="entry name" value="ENGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005201">
        <property type="entry name" value="TIM_ENGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246:SF1">
        <property type="entry name" value="CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246">
        <property type="entry name" value="ENDO BETA N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03644">
        <property type="entry name" value="Glyco_hydro_85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="1">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="714" mass="80409" checksum="7E8AEC454A31AB3A" modified="2013-05-29" version="1">MPSTHPSPNALTVQSPSEPEYFPSLFSFEQYMLSPSPLPPALPLRSRPTSSEPAGKLVICHDMAGNYPKDQWAPMWSFPWWSKADVFIYFSHYRVGSPPRAWINAGHRQGCQVLGVLIFEPGNGEEDQYRLFLTPQKTLETKYADLLVELARQRGFDGWLVNLELRYYSHVSLLVKWLEYLTTRARHILGEKSCIMWFDSITTWGWRSHQNTLTHLNAPFFQAANMLHTNYWYTPSKIRAAETYLSGPGGRLAQDVAFGIDMWGRRTFKGGGYRACLALDEIRPQGRKFSTSLFAPAWLWESGELYPASGNTRQDWWDRETLFWVGRSTPVEEERNLKRLNTDKSKQLQKGERFQPISRYFPPKPLALPVGTTFSLGLGESFNVHGERVLDSPWSDHELVAPLPGSAMPASLGRDMSTGTVALLTGEVVEDPELAWFGAHCFRLSLPEDVEGGRGRYFAPLFPVVCDGEGEGCVLVAEVTWTTGTCTPPSPSPSHLMGWSASASDTPLSTECVPVSSRDGKVQWNKTTTVFPNLQGLVNFGIVVDFGQPGALFLGAVHIRRAVLFPPIGQTPAYVTPRLYCDSPRFSFSDGEDCGVFTWRTRMGTPPEASRSEEEPVLREITVSVHGFDASSERLCWGTTSLDCWGFSWTELEARRTLQELEEKGGWVEITVRLIDWSGYWLEGARCALRVLLMGRKVLDDSFNEFNERDRIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J1</accession>
    <name>M5G5J1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Zds1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_99140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630384.1">
        <property type="nucleotide sequence ID" value="XM_040777567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5J1"/>
    <dbReference type="STRING" id="1858805.M5G5J1"/>
    <dbReference type="GeneID" id="63692629"/>
    <dbReference type="HOGENOM" id="CLU_319117_0_0_1"/>
    <dbReference type="OMA" id="PAHEKHE"/>
    <dbReference type="OrthoDB" id="5589766at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040206">
        <property type="entry name" value="Zds1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013941">
        <property type="entry name" value="ZDS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089:SF1">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08632">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01327">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein Zds1 C-terminal" evidence="2">
        <location>
            <begin position="580"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="766"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="987" mass="105713" checksum="EE21058971D3D3B0" modified="2013-05-29" version="1">MSASTLPASNMPSPSQIQREYSNLREIRRRSVSTEKGSLMVDPDLPELSPTSTSPIGQQGYWSEPTVPEVFSPVSEEAKVAEEAMDDPTNLFWVPAHLHPELAPGEFRAFLKAHTRSLPQNDIPASPLSPSTHSQTTVAGSGLGRKKSMLSRQYQPKENDGVENEPVPLPSRMASGRRNRNSIFRENDGPQLTIDDLQKLEELAEEASKSDDPSKLRSVLRRSLSLNVAPAFLDTVDDIAELDEADAPIIVPRPGQTLRRAARTKIRKANLPGDGGGHRFPATRKTRRTSAGRSTEDATSERPISYSDETAIFDSYGAASPDISDEGHGDFESNPPSELDHEVQVIATPALPIEVQPPTPPQPQEARAPALVHPTPQRHLAIPSPISVATQPARTPSPVSPHHPSASPPESPKSAVEPTSPTASLATSQETSSTTIHVPSTPTASTSTTTLVHPAHEKHEPHPHAAGRSAPAASPTKPAFHVTPPTKEKKGGLFSKKKDNHKLSKSKQSDNASVKSSVSEREKEKEKEGFFGSLFGGKKKAEESPHAGGLFSGGGAGQAAAAKLLGASKSGKDMHRPTSPGPGGLNNFSRYPIHVERAVYRLSHIKLASPRRPLYEQVLISNLMFWYLGIINRPAGEDPPPKKAKEEKEEAPPTPEHRPQSAGTPGKEPSERDSLLKRGNSFGRQSSPPHPIPHSPPHAATLRSSSPPPPVANHAPPKAAGSLNHNQRSAEMPIRSPQYEVQHRMIAQGQAAPGHEGMSRPGMPNGQHPGQSRQPQPGQPGAHSGMPGGSAGRPRTGSPPPGAMNPFTESHPQFAQGAESRPPMEGRAPREGRGTTPETRVLSPRGPESLGRGPPPQGANLPNGQAPAGPIPPGAHPSLVPQNPAVVMRRDELVLHLQPHRPTMAALSERNRHLASVQVPAVLASQCHLDRIAVPALALVASSLVRYSALHLAPDFLVRLDLADLLRCRHPPVGTYRLEPCLLNKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J4</accession>
    <name>M5G5J4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_105042</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630863.1">
        <property type="nucleotide sequence ID" value="XM_040768022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5J4"/>
    <dbReference type="STRING" id="1858805.M5G5J4"/>
    <dbReference type="GeneID" id="63683084"/>
    <dbReference type="HOGENOM" id="CLU_595945_0_0_1"/>
    <dbReference type="OMA" id="VIMYIAG"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067490" evidence="5">
        <location>
            <begin position="19"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="6">
        <location>
            <begin position="206"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="456" mass="50177" checksum="4A6D15785BD18E20" modified="2013-05-29" version="1">MSLLLHILQPAIFPPAFASNAFPLNGPFAFFIRIVRLFYSLLVLPLAIISAFLPTSVTGMNHASWNFAQTLLLRLSSQLLWAIGYGIPPRFVNRDRPTIPTRPRSVVIPNTTDISSCSMTVPPSNSRYRKGILADEELTTPTEIKCYWTSAGKCSDEQLTRQPQEGEKIIVYLVGGERAAVFQDPLLTLVPGGYLTGEPLKFPLPWTLAQKTNLRVMSVSYRKANTDPSNAFPAALHDVVSAWSHLISVGFHAENIFISGDSAGAGLAVTFALYLCLCHLPRPAGLILYSPWLDLTLSHPAVSDNHRHDQLTSDLIQTGARVYTQNFPLVYTDPAMLDAYRFNDAEYLLSTHSFDKLGPRHPLLSPALLSARSPLIPSLSETRFFISYGSVERFAGEIEMFVTILKNGGVEVVIDVEEGGWHNSTADAIGGKQVAVERAAQKVFEFVCPETQSSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Y3</accession>
    <name>M5G5Y3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">INO80 complex subunit B-like conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626065.1">
        <property type="nucleotide sequence ID" value="XM_040773393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Y3"/>
    <dbReference type="STRING" id="1858805.M5G5Y3"/>
    <dbReference type="GeneID" id="63688455"/>
    <dbReference type="HOGENOM" id="CLU_473282_0_0_1"/>
    <dbReference type="OMA" id="HENQRRE"/>
    <dbReference type="OrthoDB" id="2021186at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="398"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="576" mass="63013" checksum="1CD3279A996A913C" modified="2013-05-29" version="1">MADISHTTDDGQRHSTSPRTIVRQSQASSPLHLRSEQSSPPASQGEEETMAATRSSNRPKGSASARGTGRVMSTRSSGRVEQPTQLSTVITPDEDQEMESEDDGTTRPERNISKRDVNMEDSAVVNKAEEGTPAVREGDVGEGEVEDEESDPVSQFDSPVKFPEGSDDLTPPPPSPTPSPPKPVFRPNLRIKVKFQGKTPIKARPATAKGKNKLPFRRGKGEWDGRKFPDGPLSHKRRVPPTATGAPSSTPALSATPGHSIEPTPAPEDEELSPVPADFEYLEEEDMSRSLSTRTEPTNMDVDEEPEEEEDEQEEQDELEEEQAEEEEEEEEEAEEEAAVDEVEEDEDEEEDEEEEMSVPPPGRMTARQAAMKGTGATVEFIELPTGPGKKKNLTPQEMELRKQEQSRKRSLQSAQKLEDEKQATIRRLLSKQAPKTRSSRSGVSSTTAPGSSGDGSVTPQLAPAPTLSRWVSSKDGVRWAVPPEAKWLAYMGPVKRVGPGRMQEIKGETEEDVDMDGPADLGEAHVELVPPPRARPQAICAIDGCGQARKYRSVKDFGRGACGLEHLRVLNTLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Y4</accession>
    <name>M5G6Y4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_48176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631363.1">
        <property type="nucleotide sequence ID" value="XM_040774809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Y4"/>
    <dbReference type="STRING" id="1858805.M5G6Y4"/>
    <dbReference type="GeneID" id="63689871"/>
    <dbReference type="HOGENOM" id="CLU_141910_1_0_1"/>
    <dbReference type="OMA" id="KAKPYLH"/>
    <dbReference type="OrthoDB" id="1097733at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="11637" checksum="536B49F23D918014" modified="2013-05-29" version="1">MDEEPLYVNAKQYHRILKRRVARARLEELHRLSKERKPYLHESRHRHAMRRPRGPGGRFLTAEEVQAMERQKVEEGENAEEFETTEGAENTEVQLAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Y6</accession>
    <name>M5G6Y6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628474.1">
        <property type="nucleotide sequence ID" value="XM_040772908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Y6"/>
    <dbReference type="STRING" id="1858805.M5G6Y6"/>
    <dbReference type="GeneID" id="63687970"/>
    <dbReference type="HOGENOM" id="CLU_023194_19_0_1"/>
    <dbReference type="OMA" id="RFERWRP"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF5">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="4">
        <location>
            <begin position="146"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="371" mass="40999" checksum="23741FF69677AD3A" modified="2013-05-29" version="1">MPAPLRASVLGTGLSAQVFHIPFILAHPQYFTLHSILERGAAPEKSFAREKYGEGIKVVTTFEEVTGDKEVDVVVLSTPNNTHYAYAKAALEAGKHVIIEKPLTTTTTEGAELLAIAKKHNLLICVYQNRRYDSDFLTLRRLLEKEQVFGQVVEFETHYDRFRPAMTGGGTWKEKPGTGQGALFDLGSHLIDQVLTLFGTPTSLTGFVGNSRQLGDPSFADSFLALFHYPVTPQRPLPLTIIIRGGILSLLNPQLRYVVKGTKAGWVKHGLDVQEPQLRRPVLMSLSDPEFGVEPKELEGTLTTVDANGAMKSEKTPTEKGDYTLWYKNVGEALQARDPGLLAVTPEQGLEVIKMIELIYQSQKEGRTVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G744</accession>
    <name>M5G744_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631438.1">
        <property type="nucleotide sequence ID" value="XM_040771860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G744"/>
    <dbReference type="STRING" id="1858805.M5G744"/>
    <dbReference type="MEROPS" id="S10.001"/>
    <dbReference type="GeneID" id="63686922"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OMA" id="VANKLWV"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140983" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="490" mass="54689" checksum="949A154CC63E3D56" modified="2013-05-29" version="1">MHWFTLTSLTALLPLVGAAVTFPASHQAVFEKERRLSELSALDFVTLSHPSYPAHSVRIKRTEGFCDTTVNTYTGYIDVDYGAKHLWFYFFESRHNPDKDDVIMWINGGPGCSSATGLFMELGPCLINPEGTGENRTKYNPYGWNEVANIFFLDQPVGVGYSYADFGETVSTSEDAAKNVQAFIVIFFETFKQFQGRAFHMAGESYGGRYLPIFASEVYDANLRAESEGFTPVNLQSVMIGNGVTDGPTLLTSFYDIQCTTASLKPFQPIGLCTQMRQAVDKCDEWMMQDCFHRQDAISCQAAMTYCRSALHAPIIEAGRNPYDVSKMCEGGIGDSLCYPVTKKIAAYLSDPITKSLIGSTEFSGNFSSCSPEVMKGFVGHFDSLHLIRYYVVGLLERGINMLFYAGTYDAQCNWVANKRYTSLLDWHGKEQFNALPSRGWNVDGKEAGVARSYKELTFATIYGAGHMVPTDKPAEALEMVKRWLKDRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7I2</accession>
    <name>M5G7I2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_107566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
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                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">DJM-731 SS1</strain>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT99837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768853.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63683915"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16406" checksum="F9BB6B7F34F7BEF3" modified="2013-05-29" version="1">MPVMSTHISRAARAQSLVFNCPELAEGILRFMDRNSILQLMLAGRQFWEPCAYQLWHTLDSFDPPMRLLPSDLWLWTILGFIDELGVTRPLLDEDVARWKLYAGFVRMWPKARILGSRCSEVRGLLWMIRKVDLMRKLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X2</accession>
    <name>M5G7X2_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_26404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040774283.1"/>
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    <dbReference type="STRING" id="1858805.M5G7X2"/>
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    <dbReference type="OrthoDB" id="2506088at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="97" mass="11202" checksum="E645A71D1D42D8A5" modified="2013-05-29" version="1" fragment="single">LDVHIATPVKILHTFLLGIVKYLWDRPTHPLDTGGVALLEMRLASLHESGWNVPKINTTYMIQYCQQLLGKHFKTLAQCMPFIIEDIVTWQMLEAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G809</accession>
    <name>M5G809_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin NSP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Nuclear pore protein NSP1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoskeletal-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_113064</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nucleoporin NSP1/NUP62 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633240.1">
        <property type="nucleotide sequence ID" value="XM_040769553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G809"/>
    <dbReference type="STRING" id="1858805.M5G809"/>
    <dbReference type="GeneID" id="63684615"/>
    <dbReference type="HOGENOM" id="CLU_018823_0_0_1"/>
    <dbReference type="OMA" id="EMMSKQV"/>
    <dbReference type="OrthoDB" id="344345at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000040">
        <property type="entry name" value="Nuclear pore glycoprotein p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026010">
        <property type="entry name" value="NSP1/NUP62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084:SF0">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="16">
        <location>
            <begin position="630"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="271"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="342"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="856"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="761"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="367"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="465"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00078941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU06346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="897" mass="86268" checksum="177BC5FF535646B1" modified="2013-05-29" version="1">MFNPAEANKPATPSPLGQQPLNPNPMTPAPGNTGQPSLFPPVGSTTPAGKPSAFGFPQLALGGGGSAAGAGAGTGSSGNAGGGSLFPQLNAFGAPAFTSTSAFGAPGNAPSGSTSTTGTGTAAPAFGQTKPSFGSLAAAGGGAAASPFAGLGGGGAFGAPAAGSSGLSSFSAPPSGAGGSGGKGLSSFSALAGTGAPTTGNASFGTALGGGSKTGTATAPAPAPATGASTAKPPTFGSIFGPGPAGTFAPSTGAPAAPAGNLFAQFAAKPAEAVPATSTAAPSGAPPSIFSKPAPPAAPMSTTPTPSVFSLPPKPAEAATSTTAAPSIFAKPAEAATTTSAAPSIFAKPAEGTTPATGASLFPPKPAEAAAGSAAPAAPKPFSLFPPSGSTPAAAPTAAAGAAATTSTTPAPFSWGNFPKPAATTTTPAAGAPAGSLFPALNKPSAPEAASTPAAGTLFPALGKPPAALASTSGPTTAPATAAPPAFAGFSLPKQPAASTSAAPSAPGSTGAPEGGEKKNPFEAFGKLAVPAAPTPATGAEKPNDGAAAPSAPAGLPSLGLPTAPAAGGLGGFSLLGAGKKRDTSTLGSSTLGASALGVPATPATAATGTPATLGAVTAPAPAGAAPAKTTPSISHLQGHSMEDIVNRWSKDLESSVREYGELAREVAQWDRMLLENGALIGNLMSDVNDAERTQLLVDSALEHVETQQKELSTALDGYEALLSEMFEKNLGSSPYKTLTASGLDTGSGGVRDLRPADKTRQDAYNLAERLNRELDDMGRNLGQMIETINSLNTPSTGTSLSLSSSLNPGVIAASEDPVSQIVAILNSNLGTLQWIESKGRALEEKVRQTELMVAGTAAQQDGPGGVQPGLRDSTGARGTPRRLGRSRLGASANTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F3</accession>
    <name>M5G8F3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633390.1">
        <property type="nucleotide sequence ID" value="XM_040767755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F3"/>
    <dbReference type="STRING" id="1858805.M5G8F3"/>
    <dbReference type="GeneID" id="63682817"/>
    <dbReference type="HOGENOM" id="CLU_1890688_0_0_1"/>
    <dbReference type="OrthoDB" id="3354375at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="135" mass="14936" checksum="51BBACA00B560A12" modified="2013-05-29" version="1" fragment="single">IPHKSLDLVFSTLGTPGQWTAHLATQRPTPTLIEITTVTNATGLEANWGTKFPWYARLLIDFAAWYLHPRVPKGVKFVAHNTAFLPQDLAAMVKEAEEGRLNPLIGTEFTLEQGAEAFDLAHKGIIGKVIFRISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U3</accession>
    <name>M5G8U3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat-containing protein 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_44284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633525.1">
        <property type="nucleotide sequence ID" value="XM_040774562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U3"/>
    <dbReference type="STRING" id="1858805.M5G8U3"/>
    <dbReference type="GeneID" id="63689624"/>
    <dbReference type="HOGENOM" id="CLU_000288_57_11_1"/>
    <dbReference type="OMA" id="LDSSMCL"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="4">
        <location>
            <begin position="147"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="32924" checksum="CDFE91EC309D51E2" modified="2013-05-29" version="1" fragment="single">DKHSGPVWGVKWTTGDDKCISISSDGSFHTWNSSDAQVLPGPAPESLALISVSCPGENYALCNSIVGVTRLVKLSSGEILGRKFDYKDGSDFGRFAPSSWSVSLHPDESTYAAVGQQGAINIYSAFHDTFGERLTSFTPGKNIFGMCVSYSPNGKRIAMSNKDGQIFVSDSNTGELISNYDSHAGCVRTLSWSKDSQELLSAADDKRLVLHDLRGHRGGIVTTFEGPQGHRSWVLSVDLSSDGKLIASGSSDKTLKIWDLETRRCVSTTQDTGEVWSVSWRPGGGQLITGGNDGHVHWWRSASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8X8</accession>
    <name>M5G8X8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633555.1">
        <property type="nucleotide sequence ID" value="XM_040771630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8X8"/>
    <dbReference type="GeneID" id="63686692"/>
    <dbReference type="HOGENOM" id="CLU_2849643_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="65" mass="6900" checksum="8920D28CCBB1FBCF" modified="2013-05-29" version="1">MTPPPGSLSGQRPWDTQAFPSKTKSSNTARAGGTVTSRPASGRADVLIQRVYRSGNSTQLNSIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G925</accession>
    <name>M5G925_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-thiolate peroxidase aromatic peroxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HTP2</name>
        <name evidence="10" type="ORF">DACRYDRAFT_99997</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629271.1">
        <property type="nucleotide sequence ID" value="XM_040777649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G925"/>
    <dbReference type="GeneID" id="63692711"/>
    <dbReference type="HOGENOM" id="CLU_029871_5_0_1"/>
    <dbReference type="OMA" id="EKIPANW"/>
    <dbReference type="OrthoDB" id="2542103at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF15">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067640" evidence="8">
        <location>
            <begin position="19"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="77"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="413" mass="44699" checksum="2D8741FB6EE4FD3E" modified="2013-05-29" version="1">MRFSALAILAAVPLAVDAYPQYAKRYASLNAEKRGKYPILRRAAAPYSDQYPYTGAKLDGQAGTGKGGVQVPAPGDTDHYYQDPPPGAFRGPCPGLNTLANHGFLSRDGITTYTEMVAGLQNVYNVDFATAVVLTLLGFVFDGDPVSQMLSIGGEAVDRTGQHGNFTGEYGGVSQHGTFELDVSLTRNDFYLNGDAYSLNGTLFGLMVETAKNTSTAENPLFDFNAMALYRLQQYQRARVENPWLYVPQLVLHNYGAATFLYEAFPSSAKNNTPDLETISSFFGAVQLEDGTWGHVGERPPPNWHNRVIPMNLADVTNGIDALYAAYPVDFGANVNGVWIPANQSYTPSTPSRKRQASGSGGDTNLICGAFQEIFITAQNSPQPYAMLEFILEKATPVMAPYNCSIPGLTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA04</accession>
    <name>M5GA04_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MTHFR-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_19745</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632049.1">
        <property type="nucleotide sequence ID" value="XM_040771643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA04"/>
    <dbReference type="STRING" id="1858805.M5GA04"/>
    <dbReference type="GeneID" id="63686705"/>
    <dbReference type="HOGENOM" id="CLU_025841_2_1_1"/>
    <dbReference type="OMA" id="KRANICN"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="10">
        <location>
            <begin position="333"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="612" mass="68019" checksum="D1B47654A3AB2346" modified="2013-05-29" version="1">MKLTEAISRDDASTIHPYYTLEFFPPRTDSGFENLLTRLSRLSVLNPIGLTITWGAGGSTKQRSLDLAEAALGENPVTILHLTCTNMERDMLDDTLDNAKARGIQNILALRGDPPRGEEYWIPCDPQFQHASDLVKYIRKRDGDEFCVGVAAYPDGHSLDEDAEIANLKLKVDAGADFIITQLFYDADGFLMWLKKVRESGVEVPVLAGVMPIQSYASFLRMTKLCASRVPPSLIASLEPIRHDDEAVKEFGVEFATDMIRTITSPNHNGPTVQGIHFCTLNLEKSTWRILDNLGWIGTTAHVLDEGKNRLIQPDSNVRPSSASLLITPHDAASAATPKEAEDTGPISHTTTTLPALPANQAVTWDDFPNGRFGSADSAAFGVRDPYKNELGMTAAEVHRLWGQPETIEDLNAMFLKHLRGHSPFSTTPWSPNPIAAETKFILPRLIEFTSKGTWTVASQPAVDCMPSDDEVFGWGPKDGFVFQKAFCEFFCEFVTLERLKHKAAALDTVKFFAANAKGEMMTNMAPGESNAVTWGVFPGKEVMQPTVIERSAFQAWAEEAFGIWSEWALFFPPASTTRQLLERVRDERWLVSVCHHDFKNPNDLWDLLLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA81</accession>
    <name>M5GA81_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_104199</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632608.1">
        <property type="nucleotide sequence ID" value="XM_040767889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA81"/>
    <dbReference type="STRING" id="1858805.M5GA81"/>
    <dbReference type="GeneID" id="63682951"/>
    <dbReference type="HOGENOM" id="CLU_739722_0_0_1"/>
    <dbReference type="OMA" id="MEWDSKI"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="90"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="41983" checksum="9F6185583C17C4D8" modified="2013-05-29" version="1">MAQGYASTSNEMTSSPSNATITPHQDLSFKGSVTANGNDADMVDIIVDSAFEDEGLLEFLKRKEELALGYRRGGFAPLSCHDRFSPENQYFVLWKLGHGMTSTVWLCRDTKDPSDQSGFKAIKVSTAEWIVLRGMNDEVSFLNPFGEHLCMVFDVLGQPLKSSTASTYPLTMLKHILKDSLLALQYIQECGIIHTDIKPDNILIMPKAAELIPLIRQQMLFCHPTGINMVSLNFLPYEYMIVPSEPLTVSMDFSHPSVALTDFSTAVWAGQNHNLRGKVQSLPMHAPKVILNARWNSKIDMWGYACLCYEYYTGKILHMPRDTSNIFPKDFFLAEMQASIGPLPPSLFKDAMFYNDFFTNEGKHLPPQLSPLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAP2</accession>
    <name>M5GAP2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632334.1">
        <property type="nucleotide sequence ID" value="XM_040767843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAP2"/>
    <dbReference type="GeneID" id="63682905"/>
    <dbReference type="HOGENOM" id="CLU_062464_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28926" checksum="7314B1ED24977BC4" modified="2013-05-29" version="1">MAKQLTTIRNVDLPCWQVLMETADANWAHTPWAGNLCSQFMKMVEQEGKEANFHLNKGPGIRRSMDGRYYIPDLNVWTWLHDNCLHADVKGWQKGDAAAFYEIAMNLFRTKFEFNKFVDEHQLGCAGIPHWSMTTRFHKAVSLNADSVRVWSPITVAKVFITSGLDESKIDVLVGYFGHRQQKAELGCTYRNNILDENGSAIVPPPVEGLPLLGLEPEGLKWSDDHTGPAAGPSHVDAAIEDETLLDYGDSDGYDRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAQ4</accession>
    <name>M5GAQ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_77900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629941.1">
        <property type="nucleotide sequence ID" value="XM_040776295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAQ4"/>
    <dbReference type="GeneID" id="63691357"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="WDIFEGV"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF79">
        <property type="entry name" value="LACTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="61"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="60526" checksum="234696C85564422D" modified="2013-05-29" version="1">MSNEKGEYEHQHPDDRTTPSPSHDVIKPGNEKIRTVNPLQEVLKEEPPHPWSWPMIRLYGCLWVSYLCSMTNGFDANTFGGFTAMSTFEDYFNVYGGGELGFMVTMYIIGNLVGGLFAGPITDPFGRRFGMILGSVVCIMGSVMQTSAQNKSTILAGRFFLGMGAVTVQTAGTTYAAELAHPAYRAILTGGYQSCFFIGTMTSTFIEYGLSGLSNPGTIEWRIPSILQCLPSVILLCFVWNIPETPRWLVANGKVDKAREVLIRYHGEGNPNSKLVKLELAEMEATISTHGSDKRWWDFRELFRTRASIHRMTTLLAFALFQNLIWPPTSYYMPLMLKNAGITDSRRQLLLNAVQTPVMIGGALINVLIVEHVSRRFLFMYGSCIMVATLSILTACTALQTTHPKLGTVGVVFIYLFLANFAMTWVPMMTLYASEIVPFETRAKAIALYNLAINAFSLINSYVPPVAFDNIGWKFYLFYIVFDFVGIFVVYFLFIETRKRTLEEIEEIFQSSNPVRTSIQMSKRAAREAREAQQAGDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAV5</accession>
    <name>M5GAV5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627960.1">
        <property type="nucleotide sequence ID" value="XM_040771197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAV5"/>
    <dbReference type="STRING" id="1858805.M5GAV5"/>
    <dbReference type="GeneID" id="63686259"/>
    <dbReference type="HOGENOM" id="CLU_395880_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="696" mass="77189" checksum="1597ACA9E6685426" modified="2013-05-29" version="1">MDDSPLTIFLTITSISHTKPKLILTYFLILKTMKEHVWVNPGLPWSPEQGDSQRLCGKEVGTAHLQHIPLGPQGETGVLSWGNTLPDTCINIKAETAYHLDGAVVSTEVQHQHIILGEACLQSLPAAVQLPDSGADCLQGSSVAPTVTIPDSARSVVSPSLSPINTPPLPALCHCDISLPTTTASSVMVNGRQLAEVQVGTEAEEGEGEDKDEEEEEEEDDKDEEVEDVEEEEGPSKFGNQVADGEDLLVYCKKDNPPRYANLDPSTSTSLSPHCPTTSALPMPPPLPRKRGHQPLIPTFYIPTREEVRATCGDTSDSLELHKPIYQCKSSQNCGTGLLSGIFKFRKHHQHHQYTIQPLTLVMPYNTHSENKHPALLDTSYDQDWLLLVQPLDQWQRSMTEENKTKMACMPAVKSKKSVVAKGTLQCLCCQCKTPARPNGRTYIKDQIENAKLGLYDLKDEPSLMDKEPSLSIPFLLDVAEDVNAVSVSDTKTSYLNLDDPWDGPSTPPHSHTPPRIPSPVPMEMDEWDPEEPPPFKDEEEPDIGISVDDLNIPISAHPLPYNFDQPTQEPWLSYLGIHASAAVRGIALLLMHMHAWYQLPHLACSILATLLYTLLEQCFILSSTTASLPATAPPHTLRTMYKQMGMWDHFEVKTLCPQCWQLEDLKEEDMDADLLDDFGLGDSPHPVADWQRFCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAZ4</accession>
    <name>M5GAZ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632973.1">
        <property type="nucleotide sequence ID" value="XM_040769522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAZ4"/>
    <dbReference type="STRING" id="1858805.M5GAZ4"/>
    <dbReference type="GeneID" id="63684584"/>
    <dbReference type="HOGENOM" id="CLU_028357_0_0_1"/>
    <dbReference type="OMA" id="CAMELLM"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="58127" checksum="D95ECF1E5B6C44B1" modified="2013-05-29" version="1">MSDPSSLPHQPPPRTSGYYIAFFLVALVWSLTPLSWAYILWCLYAPPSAVGQVLLIWAVLEAAFSIYHAHLARSIQPLRPNTPDDIVTLRQSFIRVLQAGLAPAPALQKGDLARPESPMEHVERLEKDDHRAVDFRQRIRTWFRKAPWDEITRESMLTWLAWSCFDLPLADCLASSVRRTLLYEALELIERRSGTIFPEGPMTVVPLRLTMDPIAVWGRPLVMYAVVGLLSYSFRVWYQVQHGFQVRRFGEIDYLLRIPEGWTPALGQQARHAPVVLFHGLGIGLMQYKNLLHDLASSLPDHPLLIPLQPHISQDILHPQHLAPPGRKETVSSLKTAIDALSFGPDSSGQGGVVFLSHSNGTIAHAWMMKDHPTLLRRSCFVDPVTFCLWEGDVCYNFVYRTPSCAMELLMWYFVGSELGVANALQRHFVWSSNILWYEEIRHARDPAKFVVLLGGKDVIVDTERVKRYLCANGVREGCVFDQEGRHGSALLRDEKGLRTVVDWVKGEWKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBL5</accession>
    <name>M5GBL5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytosine-purine permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_75184</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632694.1">
        <property type="nucleotide sequence ID" value="XM_040776116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBL5"/>
    <dbReference type="STRING" id="1858805.M5GBL5"/>
    <dbReference type="GeneID" id="63691178"/>
    <dbReference type="HOGENOM" id="CLU_026016_2_1_1"/>
    <dbReference type="OMA" id="AQVLSPW"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="56870" checksum="CCC2DDB1F5695B7F" modified="2013-05-29" version="1">MAKDDSELGIPLPPPGTHPLEKPPTRAFSSSSSSEKAPQEAQIVDKFAWVERVPLLRTLFIRGGVEVRGIERVPEEEREPRHAWNNLLMWISINAVLTTVPIGMLAQAFFTLTLPHAIAVIIVFSAIGSATVAFIATLGPKTGLRTMVITRYSVGYVGGSIFSIFNILTQLGFSVIAVILGGQTLYNISEKLPLVVGVIIVAVVTLIICFIGYDALHYYERYAWILLLLIFCMMYGLGGKAGYDAAAQVPLEDRGVDLAGDVLSFGAIIFSSASGWAPVAADFNCRLPANTPSYRVFWLTFIGLMIPLIFVETLGAALMTITLDAYTSAYETGDAGGLIAQTLAPWGGFGKFLLVLLAFSVIANNIPNTYSAALSIQALCPPFQRIPRAFWTVVVFVIYTVAGVAGREHFSSILSNFLAVLGYWTAFFIVIVAEEHFIFRRKDGLLGGYDLTAYDSPSRLPVGLAGIFAGCCGVAGAVVGMAETWYVGPIAAHIGPFGGDLGFELAAVFSGVVYPPLRYLEIKYFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBW2</accession>
    <name>M5GBW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628410.1">
        <property type="nucleotide sequence ID" value="XM_040768582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBW2"/>
    <dbReference type="GeneID" id="63683644"/>
    <dbReference type="HOGENOM" id="CLU_1343203_0_0_1"/>
    <dbReference type="OrthoDB" id="10553933at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="204" mass="21796" checksum="EE943B070764A485" modified="2013-05-29" version="1">MRGLLPSILLGASLVYGLSLPILGGFSYQINGSIIAKYPSGGDTLCYFQIGACESQSLSMYASNFTADLSISGPQNLPCTEPLPNWNLDVQNFGGVLRRLISTAPYTPPADGIHESGIWIISPTMQITAAWTNTDGSNVNLGFAWDGVYVYATPNATGFAAEQNIEDGGDCLSVVELFFVPDCTGILIDIPGLLDWCIELPLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC76</accession>
    <name>M5GC76_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Histone deacetylase</fullName>
            <ecNumber evidence="2 10">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_44684</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 10"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633528.1">
        <property type="nucleotide sequence ID" value="XM_040774600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC76"/>
    <dbReference type="STRING" id="1858805.M5GC76"/>
    <dbReference type="GeneID" id="63689662"/>
    <dbReference type="HOGENOM" id="CLU_007727_7_4_1"/>
    <dbReference type="OMA" id="RCHTDEY"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF2">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="15">
        <location>
            <begin position="30"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU06634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="49920" checksum="BBF2B0139561A2CF" modified="2013-05-29" version="1">MDDLQLPHTPRRVSYFYDPDVGGFAYPYQHPMKPHRMRMAHALIGSYGMLGRMQVVRPRRANELDLTRFHTDEYIQFLKTITAENYMEWTANKKFCQTDDCPPWDGLFDFATLTAGSSISAAHSLVTGHSDIAIAWAGGLHHAKRTEASGFCYVNDIVLGILELLRVHARVLYVDIDIHHGDGVEEAFYTTDRVMTCSFHKFGDFFPGTGTVSDIGKGRGKGYAVNFPCRDGFTDEKFVEYFKAVVGKIMEWFRPGAVVLQGGADSLAGDKLGVFNLSMHGHAACAAYVRTFNVPLMMVGGGGYTVKNVARTWTYETAVAIGCQTQISPDLPNNEYLEWFGPRYKLEVLRNNMEDYNSSEYLEATKEKIFENLRGLPHAPSAPMARNSEGAERKVWKGDDWSDEDSDIDDLDKRISGTLLVFPLCGKFGSWSFLYFRAIARQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCF8</accession>
    <name>M5GCF8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Dihydroxyacetone kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_22161</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628640.1">
        <property type="nucleotide sequence ID" value="XM_040772709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCF8"/>
    <dbReference type="STRING" id="1858805.M5GCF8"/>
    <dbReference type="GeneID" id="63687771"/>
    <dbReference type="HOGENOM" id="CLU_017054_6_0_1"/>
    <dbReference type="OMA" id="GISQLEM"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="UniPathway" id="UPA00617">
        <property type="reaction ID" value="UER00669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019588">
        <property type="term" value="P:anaerobic glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="14">
        <location>
            <begin position="9"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="13">
        <location>
            <begin position="396"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="11">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="54"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU01743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="592" mass="61838" checksum="FAC3AD741819CBA8" modified="2013-05-29" version="1">MTTKHIFNNQQGLVVKGLHGLISSNPILRLDAHNKVVYNSQAHPDRVSVVSGGGAGHEPFAAAYVGDGMLTAAVSGEIFASPSTAQITSALSLIPTGKGVLFIILNYTGDALHFGLAAEKARAKGIKAEMVVVGDDVAVGRKQGGLVGRRGLAGCVLVCKILGAAAVKGMDLENLAAFGRHIVANLGTIGLSLDHCHVPGRTGEWESLEAGSCELGMGIHNEPGVRHIHQQPDPKHLVDEMLTLLLGDDTDRNFVTWKEDDKNGENGEGPVLMINNLGGTSTLEMSAFAEEVVSQLASKWSVYPTRVLSGVYMTSLNGPGFSVTLLNTSGVQYQVHLLTLLDDVTTATGWAGAHGGWPKGKRNLAAEAKQTEALLLSGTEAEATDDRKGPKNANPKDIESAIRAACLKVIASEPDLTKWDTQVGDGDCGITFATAAQAVIDGLGTPALPTTFASQTIASIVHILEPTMGGTSGAIFSLYLTALSGALQTQPWNEAAHSALEALLKYTPAREGDRTLVDSLSPFCKALKEGKSLDAAVKAGAAGAEHTRGMRARLGRATYVGDGTTGTEGLPPDPGAWGVAELFKGIQEGLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCJ1</accession>
    <name>M5GCJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_92330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633134.1">
        <property type="nucleotide sequence ID" value="XM_040777061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCJ1"/>
    <dbReference type="STRING" id="1858805.M5GCJ1"/>
    <dbReference type="GeneID" id="63692123"/>
    <dbReference type="HOGENOM" id="CLU_007739_0_0_1"/>
    <dbReference type="OMA" id="MGWLEGI"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06869">
        <property type="entry name" value="PX_UP2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="306"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="967"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="974"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1102" mass="122107" checksum="34A7066E4B6B5BAA" modified="2013-05-29" version="1">MDAMDMLDLLRTETPVTAVPAPPTTTTTPTTTVTPTITTDTAATTTLRTQESDGRPVPERKLTKPDRALPSTPTETDNKLAQSMANSLILQPSAESSSTSIYSDTPSEPAPVPPELVELPPSQPPSARTDDTHLTPLRAHYLKKTLVELELSQELQLLTTPPHNPEVSTLSFLGSPFAPAPKGAQVEDLPLLRYMFRQFVLTFPFLSAAPKDFFSGKLQPFVASLLSRNLGAANPLLDTEDDQTEAQSRRRMFQKMEKHIGLVLGAATKLSEPEDVVRLTQKDLERLEELARRRKRRVREEDVFDVNIVSVRSVIAKGRVRSRAHEEFVVRTRRSDFPDIFVSRRYGDFRTLAEELRKQHPMENVRPPPGKDKAAATFTQAASSSIRSMYGGNGSGSGSGSGSVSQANSNSDESLPKSFPGSFTPTPQSSGYSSPSGSVSGSAYAQQATSLSREKNRLTLRAYLHSLLANSALASSPVLRSFLTANPIKLSPEEEVDMHRREEADRVREEGRKRFAKEVAVRVEGLRGAVREVKGNLMAKDGLTQIFSTVKITSDIKNLPADYQAVIAWGRISLAAAIFQTFVASDTGSETLANLKRIHGMMPYFMLKGILRISNPIAMIRGVLDLFLAAPFGGPSLLQRMFSTSLSEEVKGLQEDIQGVKDKIQDDVLCEKVKIFVDAPAEIQQVYKADAEEENIALLAVIFRSPEGPPLDRDQFQRVVRASRAHATYLHQRASLDDSDDDTGPSEDEAWLFEDLGILLKLSARLKDREQMLALIFEGSTAELLKDIITIFYSPLAQVYKAASIADSLGDLQTFITDLIRTVEAVEELRQEDPHRTVQTFIDLVQRHEQSFYTFVHRVHSKGAGLFDGLIRWIELFLDLMREGLGSPVSLEFILPAADTERAEIFREVDKVAHYHYRLKVAYEEKLRRRFNNGRNDTATQKEEEIARDLVDGVVRDLSFGELVRGDATGIAAEESDDEKSDEYDSDESDETTEESESEVSTQTPSVEERKPMHRPTRSATITSHSSQRTASTLTRRATVGSTLKKPALEAPRSSSGMGQLPKPKLPKQAGSDLQPPDLKHIPILVPIFVEIIRPSLIPRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCK2</accession>
    <name>M5GCK2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_49925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630821.1">
        <property type="nucleotide sequence ID" value="XM_040774951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCK2"/>
    <dbReference type="STRING" id="1858805.M5GCK2"/>
    <dbReference type="GeneID" id="63690013"/>
    <dbReference type="HOGENOM" id="CLU_956554_0_0_1"/>
    <dbReference type="OMA" id="NIMKCAR"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="33283" checksum="114CB8F473FCFBF0" modified="2013-05-29" version="1">MVALTGLRVDYSRLVVLYNEKYKSLVNLRRNASSRLQHRLLNISMVDVKLFREELQSVLLRPSEDTGSGIDWPALMGHVIASHADRLSFLQHILHALDRHTDMGQREYHDVPRLISDVRQQIMTMLAPCISRASFSGMNGTKLNDTWFEATMERCSTRYTSHLPVDRLSSQELVLKTAVEETMHEICRTLLIVWRTAYSAEAIIPSYEQVALVETWMVEIDRLIMRLDWVEWQRCDPPCSPDHYCSLPQWPLDGINDGTEDVFPHCISRIHYHPLTDIRSVFPSSAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCY2</accession>
    <name>M5GCY2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prolyl endopeptidase</fullName>
            <ecNumber evidence="5">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_114525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="5"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631016.1">
        <property type="nucleotide sequence ID" value="XM_040769837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCY2"/>
    <dbReference type="STRING" id="1858805.M5GCY2"/>
    <dbReference type="GeneID" id="63684899"/>
    <dbReference type="HOGENOM" id="CLU_008615_3_2_1"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF27">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="6">
        <location>
            <begin position="492"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="784" mass="87062" checksum="A71F44E5FFB19820" modified="2013-05-29" version="1">MSTPGDSLNYDRHDGFDRIKTVNVPPLPADIVEGLKPYELAALAFNIAEFELIDETALAGHKEPRLFFMHRPQSEQMSQVYAVRSPDDKSPERLTYFNTGGGRTITNWTPVLGDNLHGKYRKGGAIFSMDLNGDEVFQLWRYWEDDAQEVPFGPVAGELDNKPGRGRIERLTNDGFKYLRPLISKQGRGNLLVFGSNLENNKDTKIYSVDLSKSGWNPVKIFDNPAGISYPASFSANEQYLIVNRSISNSNIPHYVVDLHNVTAEAKQILLPGIDPTMPVAIRSAQFLRRSGSTNIIFDTDADGDFTSVILYDLTTNSVQHLTNPDPSLRAICPIPWNVALQALTADYALFTANRDGYCDLYRYDMALNEMKPIMLPGQGENILKDIITDEANGRPNTILASITSPHLASSISELALSSSNTLVLKPYVACQTHKPDYPTSSPALIRYKSFDGLSIPAWVYKPTETSEKGKLPCVIYIHGGPTAQVRPSFRVSLNAYILNEMGTALIMPNVRGSGGYGKAYQKADDVFKREDSVKDIGALIEYISSSMPEIDTSRIAVMGGSYGGYMTFACLVHYSSLIRCGVASCGIANWVTFLESTHPSRRAHRRNEYGDESDPNVRKFLESIAPLNHVDDINVPLYISQGEQDTRVPLSEALLMFNKVRAKGLDTWLVVGEQEGHGMADQDRLEFQRHSGYDNVKTVNVPALPRDIVEGLKPYEAAALGFRLCGTEKLTESASGLDAIRFYYQHRPPGERLPQIYSVTGPSDRYPERLTYFNVGSGRVFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD34</accession>
    <name>M5GD34_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AFG1-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_74092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633479.1">
        <property type="nucleotide sequence ID" value="XM_040776049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD34"/>
    <dbReference type="STRING" id="1858805.M5GD34"/>
    <dbReference type="GeneID" id="63691111"/>
    <dbReference type="HOGENOM" id="CLU_008681_0_3_1"/>
    <dbReference type="OMA" id="ARRFINM"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF6">
        <property type="entry name" value="AFG1-LIKE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="437" mass="49602" checksum="A690561AB7B42A83" modified="2013-05-29" version="1">MTLLQFSFQLNFGSDTPTSRYHELVERGLLNKDHHQLEIVAKLEALHDRLTTYNPPLLPDAPSSSSSSLLGRFFFSNQQPPIATIDPQDVPQGLYLYGDVGTGKSMLMDLFYDTLPPNITRKRRIHFHAFMIDVHKRIQAVKNKLGAVADPIPPVARDLANEAIVLCFDEFQVTDIADAMILRRLMESLLDFGVVFVMTSNRHPDDLYKNGIQRESFVPCINIIKERLDVTDLNSGTDYRRMLKAMSKVYYSPVNDETRREMEKLFDAISEDEPVIYGRKLSVWGRDVLVPESTDKVARFSFADLCGGPRSAVDYLEITKNFPTIFVTDIPKMTLSQKDMARRFITFIDACYESKTKLFASSEVPIFKVFSEEGQSDRKEISDHMRHMMDNLGLDASMMGTTALFTGDEELFAFARAVSRLTQMGTRAWAETAGQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD90</accession>
    <name>M5GD90_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_87580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631251.1">
        <property type="nucleotide sequence ID" value="XM_040776817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD90"/>
    <dbReference type="STRING" id="1858805.M5GD90"/>
    <dbReference type="GeneID" id="63691879"/>
    <dbReference type="HOGENOM" id="CLU_007383_12_3_1"/>
    <dbReference type="OMA" id="AWRPAHE"/>
    <dbReference type="OrthoDB" id="10000533at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF3">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="293" mass="32004" checksum="DFDF277E7AE756E9" modified="2013-05-29" version="1">MKVLILGASGFIGGPVSQAFVRSGHEVYGSTRSQEKAPGLAAKEIMPLVGEEWKSIAADMDVIVDCTAAYGPDMAVPNLKTVAEISKKRDSLYKISYIFTSGTWVHGNMDQRGGFFADERSPTKKSPDLVEWRALFERDVLQNPDVNGIVIRPALLYGKSMSLLEPLFQQAMAGKIEWVGAPGDRYSLIHGDDLADLYVRVGEGASMYKGLTFDAANPQSESLDDLLAKLAQVSGCSGYSYRAPQNTFEVAMTTTSFTRPSLGRALTGWVPKKFGLVDGMQVYYKTYVASQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD96</accession>
    <name>M5GD96_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_99024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631266.1">
        <property type="nucleotide sequence ID" value="XM_040777557.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GD96"/>
    <dbReference type="GeneID" id="63692619"/>
    <dbReference type="HOGENOM" id="CLU_001294_0_0_1"/>
    <dbReference type="OMA" id="IIMWRSG"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1758"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1824"/>
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    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="428"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1763"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1855" mass="201428" checksum="ED2FD78FD12B0BFC" modified="2013-05-29" version="1">MATSASRSPSASSVRADAISRLKRAASLPRMKDGRRPAIPANGGAFSEGARSEEGSMRGADTPTYGYGDRSQSETDMVALVRPHEQEMELSHENVVEYQPTALAEDDLPTPTPREDVNDLHHAEHDVSITQAATEVHEKKPEIELEPVTVPEQTGEEEEEEEQEEEEHDEPPSQLPTAEEMLLLGLQQQMQIQRVLAGLPAAFPPSSFPTGFPPSAFPQNAFQTGLPNHQPTNQLEVVIGALLSQQQQHLQQQQQQQAASSSQPRVYRPPTSPVGWQQPIKSPASPLPSLNDLAAAHQRGLFRSNSAAARTEAYSKLTGGRETPMISPPASVLGQVSMSRLGRSHTVTGGERMAAGGRMVGVISRRQKQEDQNRAPSAMDMTTSAGEESSVSVTTREERRSRRRRRHSSQSKAVVVDDRDVPTNAPSTPAPSGTPLPQEDIPPLPPRESISSLSAANALRQSIEKRGARDNFEYDYERGRAKSATPVYYGSKPGTDVETDNEIPPVPRSPTNIPTSPSLSDLGRPLPTTPLFTGLPYPSAPYLTSQSGTHNSDGASHASSGYMDGIPVYLRTGSLQPARDSFPHTIEGTPYSLPYKSSPNGENHNKIHRAITPGYDSAAESPWNLGAGSEFHGALGDTRGRNIMDQFRDEGEEKAETGALLVESLPEPTSLGSDSANTVRAAITPSPLPPMPLTAPATITGMSSQQMQFPTAVSPSPRAPTVKPAHREVLSDISFTSVPPASTPHRSRTESVGMSDFDIAITDGETTGREDRPKKRRSGSNFSDKVKSFLSHMSSRTALRPRTTSISSRHERQQKTESNNSGELLGGKLENVESRESREKRESRDSREKQVAQFREGLLTKSVSAVSLPSQASPQFSKSLMDVTTPMPQGSISPLPPASAAQIAKYTDDKLLPFPGMLRLEQERSKLRTLSPPTSPTNLSFSPPPTSPPPGTQTTIRSGSAKLGTPSPGMTLLDLPSTPTSAPATPGTLGERMGERTLHYIDLGDNLLAGSETLPTTRRGVQQWLRMKKSSPNGNGAVQKKSSLTDLLSSGMLNESPIEKDDGAGLFGKLSIGRNTNKKSIRPRLPERQDGRAGASSSTDIPQVPIPFPAPVAPPAQISIPRHPEDSHVSTALSLVPSQPSAMLPTKPSSPAPLVPVSDQPAVVVASASNASNSLASLAAVAATYQEKSNNQSALASLADAAAVSDQPEDSHSSLASDPSGPNSHITDLSISALSTPSVSHETSSTSQPSLDSPPRVQLPHLKQYKSASTPPAGSLSLNIQPSSRTFSPKPSPPRKLLLHSPVLQVVQGDRLKERHLFLFSDILVIAKPDLRSSLTNEKGDPGSLSRPLLVKSIVEHRNLCIKPQQDHVEPVKSDKHKLTMRAFADEFAENPTVAVTKLAQRAGLQDDPGAIADVLFETPSLDKRQLGEYLCQRSSRYVLRAFIDRFGFEDVRIDIALRTFLLSIILPDQEENSDHLLNNFAARWWSANSRTIGFDRELSTRLVLAMIQLSEALHSASSVSSGKNGAMSPNKPRISVQDWIETFRIRDTRQLVPELLLRAIYTGISRFRIAESLDSNSDSEVPAAMIPARMKTRLTHGEPSERIHIRIPRPDRNFAIRLYGHGLKFDPEYLDFSNSTEQSFVIFPTTVGPKTIIFGREGGNSAFYTGVPLSKTVLVERAFMKNTFQLAFVNHLGVKRKYLFSMDDLFRVTEWTNTLSREINKRKSMEAPLREKDAERKAAADVIAFVTLRDLLLPREEKEPNSSAADTSAASYSRIGPPKSPAAKESPSDDRAYTGQQIIQTCIQNSLLASMILRAKPAKADGNFSDLEKRTPTPRLASPLTLTPRIRPGGMRMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDE8</accession>
    <name>M5GDE8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631371.1">
        <property type="nucleotide sequence ID" value="XM_040772187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDE8"/>
    <dbReference type="GeneID" id="63687249"/>
    <dbReference type="HOGENOM" id="CLU_818955_0_0_1"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="339" mass="35124" checksum="3E665075EEDECC0D" modified="2013-05-29" version="1">MEAQLKSMRVPELKELATKAGINVGAKLTKDKIISLLLESPNVAPLLGITSAGTALPAAPEPKRPTTTTAPVAARKSAPAKGSLQDLLAPSTEFDWPETAPAPAVGITTPSAAPEPVYAANPVKANIPTPATTNDVSSDVPNPTPVVPAPLPPSDVPVNPLEGTSKPVAGTTKLTEEEKRAARKARFEREWQHDQARKDAETAAKAARAAGRAKEVTGQNGSETAKQAAAAPTSANADKATKSNGTKGNGISADVIEKRKARFAQGGDQAKTSPPVAPAPQPAAAPLLSGIDAEKAAARRNKFNSLVPGQPGYEEATSPKRKWEEDSNVLPSKRVKSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDJ3</accession>
    <name>M5GDJ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase C15 pyroglutamyl peptidase I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_51919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629347.1">
        <property type="nucleotide sequence ID" value="XM_040775069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDJ3"/>
    <dbReference type="GeneID" id="63690131"/>
    <dbReference type="HOGENOM" id="CLU_043960_1_0_1"/>
    <dbReference type="OMA" id="KLAYNHK"/>
    <dbReference type="OrthoDB" id="407146at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="278" mass="30200" checksum="D818DC3FE1A72058" modified="2013-05-29" version="1">MAPTEKKPFNVLVTGFGPFRSYAHNPSWLGVFPLHNTTHPTPSHTIHFICFRVPTSYATILALILPLYARPPQLPESQYPPTPGGTKAPYEPGDPVPQALPPPPEGGYDLVIHVGAGHAGHLALESQAHKTGYRIEDWEGQLPPVVSDFLPESAPTAAERGEMARLGLGGLFAQEGKGKRGFGTGYEQFPELLPAEGDVPSLVEYLKSCGLEHTLHSTDAGHYCCDFIYYCSLAESQRLGVGKGSKVQFMHIPPPGEPYESEQVSEAIRRIAEFYAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDN0</accession>
    <name>M5GDN0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631551.1">
        <property type="nucleotide sequence ID" value="XM_040771883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDN0"/>
    <dbReference type="STRING" id="1858805.M5GDN0"/>
    <dbReference type="GeneID" id="63686945"/>
    <dbReference type="HOGENOM" id="CLU_020336_53_0_1"/>
    <dbReference type="OMA" id="FLGMSDN"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000039">
        <property type="entry name" value="Esterase ybfF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="10"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="265"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="324" mass="36125" checksum="A901EE8509ABC2E2" modified="2013-05-29" version="1">MPPNAQPGGPVVVLHGLFGSKQNWRSLMKLLGHSLKRRVYTVDLRNHGVSPQSPRMDYEIMAADVVQFFIEHRLKNDITLIGHSMGGKVAMATALSPLLEKNLPKALSTLIIVDIAPGIGKISDEFASYVDAMQDVQDADVKTKREADVVLEKWEKDISIRQFLLTNLVADKHGSHFRIPLSHLRANLDQIGKFPYPPDGTHTWEGRTLFVKGERSKYINRRNLGLCFDYFPNARLETMDTGHWVHAERPQEFVDLVTRFVHGEDPSWMSEQEAEEALATEGRKDVSAVDTTTEPPQQPAAQSEAAVNEAPESAEGPEQRATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE13</accession>
    <name>M5GE13_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_114292</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631886.1">
        <property type="nucleotide sequence ID" value="XM_040769793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE13"/>
    <dbReference type="STRING" id="1858805.M5GE13"/>
    <dbReference type="GeneID" id="63684855"/>
    <dbReference type="HOGENOM" id="CLU_035754_2_0_1"/>
    <dbReference type="OMA" id="IMFSANN"/>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="265" mass="29379" checksum="0A18A8C50AA29CDC" modified="2013-05-29" version="1">MKFRAEVSNVKYFYQVVQSVEKVAKKCIIRLSPESIEIICAEGNEEGIQVWSKINKACLYPETLFTGYRVQSNADNIICADIVTDSLVSVLRDLATTGKSGTRDTVMKLAKRNDQAVFVFETKDHVHVVIRSLGQMRGAVEKMKVLDDKIMFSANNRGELILSAETKDKDNSIRTTWVNLTHPTIEAGEGAPPRDPPDPEKHFGATMSAASLLKFMSTATINKTTCIACICENHCLIMYVYIGDPSDSNGILTFYLPARLSGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE40</accession>
    <name>M5GE40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629847.1">
        <property type="nucleotide sequence ID" value="XM_040768200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE40"/>
    <dbReference type="GeneID" id="63683262"/>
    <dbReference type="HOGENOM" id="CLU_075600_0_0_1"/>
    <dbReference type="OrthoDB" id="782330at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="35494" checksum="92802CB56567F073" modified="2013-05-29" version="1">MTAAIIAHMREDAEDPGFLLLVKYPDIMPFGNAVTLLLNSPQSALVCNLPEKWVQLFALDQQEELAALSTPAKEEEEEDEEEKKFKAMLSGFSTSLGSLASLLAKAEKGKAKAKETMLAKAVMRHLNNGMDKTSPATRACRRPMKEDSCNAGWMPEETLCMLCCKHAIVKDGKVHHNKKALQHSLSACLAKAMALPPVSVEDLFLLETPEPKPIEKPTEKPAKKKKQKPVHSYMLVKPKKHEQEDNKDLVGLSLKWSRLLEAEVKLLVMPLRMAEHKMLKLRKSLQIAQKAVDTVQKVVNTAMGWADQVQTLLGKALTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEX8</accession>
    <name>M5GEX8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7587 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU05792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040771829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEX8"/>
    <dbReference type="STRING" id="1858805.M5GEX8"/>
    <dbReference type="GeneID" id="63686891"/>
    <dbReference type="HOGENOM" id="CLU_776173_0_0_1"/>
    <dbReference type="OrthoDB" id="3359845at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056009">
        <property type="entry name" value="DUF7587"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24494">
        <property type="entry name" value="DUF7587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7587" evidence="1">
        <location>
            <begin position="28"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="365" mass="41980" checksum="44CE1648559D8463" modified="2013-05-29" version="1" fragment="single">MSPLCVWPKPPADDATLQDRLISKRQEYPFLFRVQPSDWHSSTRFDRDGNLLASFFETAAEAEYDRHNGGMEEVDLAILCKHMHWGCREPSRLISCSASPRWAFREGMRRIMDGGYLTNLVIIDGMKVREDRNACELLEELAEEECGNEEGCGDEWEYEEYGDDPDKFNRERVEHENNLPWNYENALKFGSMAEVVLVFGIIPADAILAVVDMTSPVFCHALDALYPRLSRTRCAVRKSFSDAWKRQVKYWLKQADVSEFELGERAARLVVVMLHSTCMEHLSHIKEVQKAKEYCDAAYGRMVSLSGQMLLEIFDISSEHFFIDQGIQAIITMKKMELMNSWESSHYAITLGNLVESTRRMSVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF59</accession>
    <name>M5GF59_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_21288</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Homotrimer. Homotrimerization increases the affinity of HSF1 to DNA. Interacts with transcriptional coregulator SSA1 on chromatin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630762.1">
        <property type="nucleotide sequence ID" value="XM_040772326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF59"/>
    <dbReference type="STRING" id="1858805.M5GF59"/>
    <dbReference type="GeneID" id="63687388"/>
    <dbReference type="HOGENOM" id="CLU_372549_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="10">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="510"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="593"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="630"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="694"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="698"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="731"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="746" mass="79982" checksum="FF80565AF2205B41" modified="2013-05-29" version="1">MDYAPDTASEPFAHSVASVSWGSPRLMLSPSSTELSQQSSPIQLMFPNTGLYAPPAHDGRPSTGSSIHSRPPTGPATSQLSLNLSALSVNSSDHGQHSHPADESPEMDQTGLDSSVFHSPTDAAFAAPHPYGNLYNMSAAHAGASTSPRIARHALRKRPLPQSMDEQQIQETMAGSGSVYSNAMGPIGLGIARLVPDSEPSMGIDPSQVSVSALHQAMDDTGDLAFGTDGTGSGMDGSPDSSEDADGPMNLISQGIHRGAGTIRIPSGMSVSADEGTSSGRGYSGRPPPMNNFVTKLYHMILDPKAAPFISWTDMGASFVVSSVTEFSKTVLGSHFKHNNFSSFVRQLNMYGFHKINRTPRASRSTGTDQTWEFSHPKFLRGRPDLLDEIKRKALEPDLTARQRVELPAEVANQLGGVEGRIEQIAAQLMAEKEKNQRLALVVRQLCDWLANMYPGQIPIQVPTDLLECSPHPHIYVSHTADGMPINGHPVSPSYLSPYVQHPYYAVPVPNTLTPQSTPTSSDFPDDSQQSRMLDPTCDPTDRSRFIIPQLPHSAPAGGRFMRRNVSNLSLDEVSVGSSHHGTFMLRPSASNMNLAGVDGSELHQQQQTDSPDSLEPNVLELNGQILPEVPVLSAAPKSSGRGSSKRQRPNPSPSLDSQLSMAGTESLASSTVSSNIHGKLHRVRSDSAPLGFGLGQWQGQDQSAFITPSTSAPNLSPERRPRSGTLISRRATERSGLRMASKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFF9</accession>
    <name>M5GFF9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633141.1">
        <property type="nucleotide sequence ID" value="XM_040769543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFF9"/>
    <dbReference type="STRING" id="1858805.M5GFF9"/>
    <dbReference type="GeneID" id="63684605"/>
    <dbReference type="HOGENOM" id="CLU_024949_1_0_1"/>
    <dbReference type="OMA" id="QGHEGWR"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="1">
        <location>
            <begin position="41"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="343" mass="37850" checksum="31469049AE686A7D" modified="2013-05-29" version="1">MILQKSTTLALQAGSRCAALAPSAVGMSRALLAACRTQHRDFITIVPQGHEAYRLTLGRSPTRLMPGLHLNIPVLHTLQHVDMRETSIPIADLTGFTSDNVPVLVSGSLFFRVKDAYHACFSVNDFGDNVRAIGTSAMRSVVGSFHYDAIIGDRNAINDKLRGVIGNSISSWGIECTRFEIQTFKPSNREVERQLELQMEAERNRRKQLLDTQAAVNVAEGVKQKMILQSEGEMEGKINQANGELQARLKEAEGFGQQIEIIAQAIAGHGAVVESDARLKSVEFIMEMRRQDTFRTIADGQGNNTYFLPPGLTSLSEPHEMDATQRWVRSMQDKRKSTATPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFK9</accession>
    <name>M5GFK9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_113123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633306.1">
        <property type="nucleotide sequence ID" value="XM_040769568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFK9"/>
    <dbReference type="STRING" id="1858805.M5GFK9"/>
    <dbReference type="GeneID" id="63684630"/>
    <dbReference type="HOGENOM" id="CLU_006019_2_2_1"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="792"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="645"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="810"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="850" mass="94780" checksum="12770C714681CB68" modified="2013-05-29" version="1">MASDQNSTKSLRKRRRACDACHKRKVRCDGIQQGQTACTYCLKSNRECTFESTPRKWPPSKNYVGGLEARVEHLERLLANIAPWPSSGHALPWDDAGNSAESPDEDDISEDDNRNEFFTNMRLRGFGELRIADEDDGSGRPVSGGPSKDFYPPQFERKLHEPRFFHGKTSHFMVVRQLNELLATRAPEERRLFHIRPEFTRVHPNSYFEESDVSEMNVQWPEPDLADQLIQGFFDKFNAGFPILHRPTFLRQWADPANHTKREWAALAFAVFACGAKTIDDPRTKAWPNDKYKHSAGLPYWYEMRRIAYPPYAPPTLCRLQTTVLGGLAIMGTPITPSAAWGLIGLASRLAQDAGIHRRSARRQRADPFEYEMRKRVFWAAYFMDRTMASFLDRPLAFREEDYDVELPLELDDEQLDNLQYGRKVEEGEGCLHLAAWVYRLRLLQICSRALSTLYAARNTQRPDLAEWERVILINLSSALNSLSEMQPEKLKFDPENPDDTVFLHTALVNIQYQLTQILVYRPFLHPAKLALHEDVPSSAVCSGAARALAHTISGLYTRDLLNGRTLETGLSSFSAGTLLLMDMWQRQEADSIVEVEKCLEALTYLEQTWQMGGMVRDILTGLLQLTKTAMYRSSGKRRKTGDNAGSAGFAAGGSVPRGPSIASSTSLSSGPSMTDVSSTLSTPAYPPATLQPALQPIVHSIQQPLAPMFPKSTQVSFDTTALPHQQLFDPIVPMPLDASQEQGPDFLTQIFASTTVPVTSDPAAEQYSLLGDEMFDANFTEWLSAMLGASQHATPPDATASSGGSDTFSPPPGSGPTPGPATATTVDQMNTDGVQNMFLNTYQGNYGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG25</accession>
    <name>M5GG25_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterol-binding-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631642.1">
        <property type="nucleotide sequence ID" value="XM_040767959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG25"/>
    <dbReference type="STRING" id="1858805.M5GG25"/>
    <dbReference type="GeneID" id="63683021"/>
    <dbReference type="HOGENOM" id="CLU_105945_0_3_1"/>
    <dbReference type="OMA" id="WTIDMKK"/>
    <dbReference type="OrthoDB" id="10265837at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1050.10:FF:000001">
        <property type="entry name" value="Putative Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF28">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="131" mass="14317" checksum="2561CD1C5EC61247" modified="2013-05-29" version="1">MSDIKEPGFKSSELFARLAEVLEAYTPEEKAKELKKTNGIFEMQIKGASGEVKTWTIDMKKEGKVVKGKPAPKPDVTIIAGDELFLDLAEGRTNGQKAFMTGKLKTKGNMMLATKLDAVLKTAQGELKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG32</accession>
    <name>M5GG32_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_36829</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631677.1">
        <property type="nucleotide sequence ID" value="XM_040774416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG32"/>
    <dbReference type="STRING" id="1858805.M5GG32"/>
    <dbReference type="GeneID" id="63689478"/>
    <dbReference type="HOGENOM" id="CLU_045864_1_1_1"/>
    <dbReference type="OMA" id="WSNKYYP"/>
    <dbReference type="OrthoDB" id="9979678at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.570:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="255" mass="28704" checksum="989758586DE005CF" modified="2013-05-29" version="1" fragment="single">IDALLDLMRRLPPQHVQQNLDKLVQLAAEDAEELVSSVDVPLRIATCKQTGKTYLCCDYNKDGDSHRSPHSNEYDPPLPDGTFPSVKLRKLEVSANEAFDTYREMYFEGGISSVYLWDTDPGAFAGVVLFKKRVFPSPDSWDSIHVFEALEKGRMANYKLTSTVMLTISAPGSEEGVVSLSGSMTRQQEQDLPITSIQTHIANTGRMIEDMELKMRNQLQDVYFGKTRDVVGELRSAVGDEEERRRRDLAKELQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG52</accession>
    <name>M5GG52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM4</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM4</name>
        <name evidence="7" type="ORF">DACRYDRAFT_63163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG52"/>
    <dbReference type="STRING" id="1858805.M5GG52"/>
    <dbReference type="HOGENOM" id="CLU_044783_1_0_1"/>
    <dbReference type="OMA" id="PTPSFQF"/>
    <dbReference type="OrthoDB" id="10069295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="71"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="26763" checksum="916B22EB640AC2FC" modified="2013-05-29" version="1">MTDTDASSSLVDFNPSRLGTKEHWDGVYQREIGSFHEIADEGEVWFGEDVLQKMIDWALENVPPTPDSPYILDIGTGNGVTLFGLAEVGYPLDQLCGIDYSNHSVELARAIAANRGMSQITFKQCDILFDTPAHLENMSDGQGWDLVLDKGTFDAVSLGQYEQLEQPASRLYPIKVGALLKEGGMLLITSCNFTEAEIRNLFETSASRLQFHSHVKHRTFSFGGQTGTVVSTTAFVKTTVSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGL1</accession>
    <name>M5GGL1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_75000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632572.1">
        <property type="nucleotide sequence ID" value="XM_040776100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGL1"/>
    <dbReference type="STRING" id="1858805.M5GGL1"/>
    <dbReference type="GeneID" id="63691162"/>
    <dbReference type="HOGENOM" id="CLU_007383_19_0_1"/>
    <dbReference type="OMA" id="FYYLDIL"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF3">
        <property type="entry name" value="ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38038" checksum="EF228A5B97B16446" modified="2013-05-29" version="1">MSVPVLPAHLKTILITGAGGFLGDRIVTYLLTHYPDIKLVICDIKAPAERPGGRVTSVGADLTDPKEAEKLFSYGKIDGVFAMHGIMSGGSEANFDFGYKVNVDSHRYLLEATRQHGAKYPNDPKILYVLTSSLAVYGGPLALPESHVNPDATPITPESSYGTAKAIMEMFVFDYTRKGFIDGRSVRLPTVSVRAGAPSSAASSFISGLIREPLQGLESVCPITNDPKDPIIDNMRIWIGSPKAVVRNLVYTITVPAGKYPKHHRSINIPGITITTRDILNALEKYGGPEALKHVKYNLEPQTYAICRTWAGSYDNTLAFSLGYENPDEKTGFDGAVADFKEELFAAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGP0</accession>
    <name>M5GGP0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit WBP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_20189</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632717.1">
        <property type="nucleotide sequence ID" value="XM_040771840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGP0"/>
    <dbReference type="STRING" id="1858805.M5GGP0"/>
    <dbReference type="GeneID" id="63686902"/>
    <dbReference type="HOGENOM" id="CLU_031804_1_1_1"/>
    <dbReference type="OMA" id="AHDEYPR"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140969" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="292"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="48974" checksum="7A823C1FBA3A31DA" modified="2013-05-29" version="1">MQQRLLSWLAITLTVLASAWARSSAGDKVLVVSDAKLEAAEYSQFWDGLKNRGYELTFRKTSEEAPATSSFDVPSFSHIIVFAPSTKTYPADISPQSLVHLLSDPTQPTNILFVLQPSTPSSPLRDLGREFGISFPPPATPLIDYFNAVSPSNATSLLLTPPVTPHTPGFNGGDVLYSGVAHLRSNNPLLVDFLNAPPTSFSADPLEPADVIVEVAASGGEGFWAGGRMGLVTGFEVLRGGGRATWVGSLDLFRNAATAINGKPTANNAYALALASWTFQETSVLRIDSVEHRRISESSPRDQYRIKDDLIYRIHVSAYNPATGEWEPTSQIDDMQLEFTMLDPHIRTALSPVQGEKGWYETKFRAPDRHGVFKFIVDWRRKRYTALHSSTTVSVVPFRHNEYPRFLSSAWPYYLGALSTSAAFVLFCALWLLGGNEEEKKKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGQ0</accession>
    <name>M5GGQ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase SUV3 DEXQ-box helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_104362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGQ0"/>
    <dbReference type="STRING" id="1858805.M5GGQ0"/>
    <dbReference type="GeneID" id="63682975"/>
    <dbReference type="HOGENOM" id="CLU_536375_0_0_1"/>
    <dbReference type="OrthoDB" id="72269at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-dependent RNA helicase SUV3 DEXQ-box helicase" evidence="7">
        <location>
            <begin position="410"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="508" mass="55588" checksum="895B45B2931C1E32" modified="2013-05-29" version="1">MSTKDAATPTSREKPASPSAPSKNPAKTLASVPLPAIVIVLIFSSLSAIAWAIIWTPVRNQSPDATLTLMTFCPPKGPPARYALVPAWLGGWTVLANDALCQLTTFFSLIIHSPWPEISPGTAPGGGGRELTWELVVTIIPVLGVLFLEAERPSASVWIRYPVFWGLLYQNIAGATIFPICYMLLFVTSPPRLPIPSHRGEAVFVGIIIGYGIPTLGMLFFQDDRWALLWQFFPLTVPVARDVWATIRPAAKGPDPELGDFWARMAQGLGVVLGTVVHVLALLEAAPLDGGYNRMWTAYARTFLPVLPLPNPLQDPQGHLWHSLANFLKWNWIFIWLSTWVAALIAVVQTRTARARKEFQELGTWALMAAAFVLMGPAASFHVPPATLSSLIPKFLTDARNQLSHPDLHVARKWNLLARACNLLTGEEQRWVGERASHLACTVEMTPCGTELDVVVLDEIQLLADPDRGSSWMQVLLGANAQEVHVCGEDTAVGLVQRIAEECGTSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH34</accession>
    <name>M5GH34_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_113224</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633437.1">
        <property type="nucleotide sequence ID" value="XM_040769590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH34"/>
    <dbReference type="STRING" id="1858805.M5GH34"/>
    <dbReference type="GeneID" id="63684652"/>
    <dbReference type="HOGENOM" id="CLU_031900_2_0_1"/>
    <dbReference type="OMA" id="YCYCQKL"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16858">
        <property type="entry name" value="ING_ING3_Yng2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="220"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU06543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="284" mass="31816" checksum="7E2FF659B6AB2E2A" modified="2013-05-29" version="1">MTMEESAQIAAEYIASLDNLPNEVKFILNEIKLKDTQLQSTIGRIQSREVNLFKNTRNNKPPINYADENVTTREIEDLFQKARKLSDENVELARRLKRLIHKAKGRLAADMKKITKLTGEPIAEDLTPSATRGVDKIAEGLRQALATPSSASPAASGPAQKKRRLTSSQVEKVVLSLPLGRSRLSQVQPSPLRKSTTVRSPDASEEEAEEGEEEDESDDNIYCFCQKKSFGEMIGCDNEQCRYQWFHLECVGLKPPLPDSWYCSDCIKKGFGSAGEKRKGRKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNH1</accession>
    <name>M5FNH1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624333.1">
        <property type="nucleotide sequence ID" value="XM_040771392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNH1"/>
    <dbReference type="STRING" id="1858805.M5FNH1"/>
    <dbReference type="GeneID" id="63686454"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OMA" id="WTFRHRI"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="336"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="49720" checksum="A768C83B2AA62E22" modified="2013-05-29" version="1">MTFLPAQSGDCFISMLPEEPHRSEHGTFPTVQQLVHEGWGLEKNYTEPRGENVGDMIAFLGSSSGTTGLPKAIAVPHRSVIAVSMQMTAHYKANEKGLSDEDRWIRPGDLVLGVLPFFHVYGLVAILHTLCYSGAGIVVVPQFSLEPCLKTIVTRLITHLPTFPSLVPSIIVLLVNVHNTASKKYDLSHCRWVVSGGAPLSSTLLTQLRARLPGARIGLAYGMTETTGLVCMGDFHKPCPEDSAGYLLPDTMVRIVKADGTTAESCEPGEIWVQGPQNTLGYTNDKKATEETFLPDGWVRTGDEGYVKSDGSVFIIDRLKELIKVRAFQVAPAEREAHLLEHPSVQDTGVIGVPDEYKGEIPLAFVVLDEPTTKRAASSRQEEMKVKQELTKWVSDQKVRYKWLDGGIEFVDSIPKSPSGKILRRLLRDRAKPVLEKKDQKDQRAGEIAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNN6</accession>
    <name>M5FNN6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_25075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624633.1">
        <property type="nucleotide sequence ID" value="XM_040773994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNN6"/>
    <dbReference type="STRING" id="1858805.M5FNN6"/>
    <dbReference type="GeneID" id="63689056"/>
    <dbReference type="HOGENOM" id="CLU_033361_2_1_1"/>
    <dbReference type="OMA" id="QRTEYNK"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000079">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="395" mass="44526" checksum="F1AE3EE253EAC288" modified="2013-05-29" version="1">MSHRKYEAPRHGNLGFLPRKRAARHRGKVKSFPKDDPKKKPHLTAAMAYKAGMTHVVRDLDRPGSKMHKREVVEAVTILETPPMIVVGVVGYVETPRGLRSLTTVWASHLSDELKRRFYKNWYKSKKKAFTRYAKKHAENGGKSIARELERIRKYCTVVRVLAHTQLSKTGLRQKKAHLMEIQVNGGSVGEKVDFAKGLFEKPVEISTIFEQDECVDVIAVTKGHGFEGVTHRWGTKRLPRKTHKGLRKVACIGAWHPSKVMFSVARAGQNGYHHRTELNKKIYRIGSGADESNASTEADTTKKTITPMGGFPHYGIVKNDYLMLKGSIPGTKKRVITIRKSLMVHTSRRDLEQIQLKFIDTSSKFGHGAFQTFEEKASFLGALKVRASAVFGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNS4</accession>
    <name>M5FNS4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS17 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624768.1">
        <property type="nucleotide sequence ID" value="XM_040773867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNS4"/>
    <dbReference type="STRING" id="1858805.M5FNS4"/>
    <dbReference type="GeneID" id="63688929"/>
    <dbReference type="HOGENOM" id="CLU_073626_0_2_1"/>
    <dbReference type="OMA" id="DYEKCPF"/>
    <dbReference type="OrthoDB" id="10254436at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1000:FF:000001">
        <property type="entry name" value="40S ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_uS17_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="17670" checksum="94AF7ABFF7E04181" modified="2013-05-29" version="1">MAEQIEKAYQQQHLFQNAKRVGGKVSTKTKRWYKDVGLGFKTPAEAINGTYIDKKCPFTSDISIRGRILTGRVVSTKMTRTIIIRRDYLHYVPKYNRYEKRHKNLAAHVSPAFRVELGDMVTVGQCRPLSKTVRFNVLRVAKSKEATKSFEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNU6</accession>
    <name>M5FNU6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_84289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624838.1">
        <property type="nucleotide sequence ID" value="XM_040776672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNU6"/>
    <dbReference type="STRING" id="1858805.M5FNU6"/>
    <dbReference type="GeneID" id="63691734"/>
    <dbReference type="HOGENOM" id="CLU_022571_2_1_1"/>
    <dbReference type="OMA" id="TLWHPHE"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="328"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="414"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="512"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="545"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="578" mass="65139" checksum="6749BD292FC1A5B2" modified="2013-05-29" version="1">MTGLVQEYASDSDDSRVPTPTVDDAFGLFELPAAKRQRTDNSLNNAVGASIAPDDALNQASLVTRPTDTQIMVNIKIDDMLRPAQGPENPFADRRFQNQNALAGVVEEQAMTERDFRAQHLSYSILGYAANPSFAADVPVLGSLAAAKNNNFQTLDMMRATSGERKQWKRKRNDRGDLEIVDGEGAYAGPWAKWAGDEQPEMIVPEQDEEPEEENPEFEARKIKARRQAFGQEKSIFHGKSVADYQGRTYMHPPVDIAPNLAREEGSQECFLPKECIHTWTGHTGAVSVVRLLPKTGHLLLSGSMDTRIKARLLLWDVYHEGNCLRTFMGHHKAIKDLTFSNDGRRFLSASHDRLIKLWDTETGQCLKAFSNGKTPHVVKFHPDEDKQHIFLAGMHDKKIVQWDINTSEIVQEYDQHLGAVNTITFVDENRRFVTTSDDKTIRAWDFDIPVVIKYIAEPHMHSMPAVTLHPTGKWFAAQSLDNQILVYSADTFRQNRKKRFAGHSTAGYACAVGFSPDGRWISSGDADGSIVFWDWKTGRLMKRLRAHSKVVICHEWLPHETSKVVTGSWDGLIKLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNY2</accession>
    <name>M5FNY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623536.1">
        <property type="nucleotide sequence ID" value="XM_040774224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNY2"/>
    <dbReference type="GeneID" id="63689286"/>
    <dbReference type="HOGENOM" id="CLU_1865065_0_0_1"/>
    <dbReference type="OrthoDB" id="10360377at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="137" mass="15548" checksum="3DFC9A6963E1BF83" modified="2013-05-29" version="1">MSSTQWMYTYGLERGRKVERDTYTPGGGTREEINNVLIYRLTPPGQPAVPGVGVQKEDLAVAGGGVDMTSLSESQERDWVSKFFIWRVLMELKRIGRVRVSDPGCLWDEVCREVTEGLEERVRGSLEPRVIQCSYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP11</accession>
    <name>M5FP11_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_102771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623596.1">
        <property type="nucleotide sequence ID" value="XM_040767666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP11"/>
    <dbReference type="STRING" id="1858805.M5FP11"/>
    <dbReference type="GeneID" id="63682728"/>
    <dbReference type="HOGENOM" id="CLU_506241_0_0_1"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="62226" checksum="8BF53A14A021E540" modified="2013-05-29" version="1">MARVPLRSNGRDGTAPSKKRKVTARKEDKSASRNRRRTSQEDSKAGALAFLFEAPTEIVVDILSLLKPLDLLHLSVVNKELRVFLTSPSAKIIWLSARRNVGLPDELPPDFMETAYARFLFVPTCELCDGPAKGMNEMVYLRVRLCRTCRDAKNHTSRSCNAQEAYDKVGTFGGSLALLPGLDVHTRPDSGRLPSKRDRYVSFHIDALGKKLRSLRRTASKRQFMTERETLIQRVRETREPLLEWIKQTRQETRDERDELMERRVDAICTHLLELGHSERDVCAIEFVAHPVIRKAELFNDQVWNANRAKFERILQETKAEREQEERQVQNESVLREIFTELWEALPTDEERWTFLPVHDFLSLPSVLNISRNTVDIDNVRGAFQSHREIILEEVARFHEEMRTQLVHLLWTEAIHQGISETEIRAATDEDRVRLLRKAVNGFVVAPMFGDERILNYHTMFKDGFFVNDGDDPHGDFHHPHIIWPWSQLLRCIQGIPFVMSLIIEDAGLDEETATFDELDAANPEWREQLLDVEMGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQD7</accession>
    <name>M5FQD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623812.1">
        <property type="nucleotide sequence ID" value="XM_040769383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQD7"/>
    <dbReference type="GeneID" id="63684445"/>
    <dbReference type="HOGENOM" id="CLU_653862_0_0_1"/>
    <dbReference type="OrthoDB" id="10604800at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="420" mass="46583" checksum="BD63B035F82C205D" modified="2013-05-29" version="1">MSSPQPVAHITFKRARKSGNYLIDKSYPVISPYRVSPSRSRRRHSSVIVDSNNREIPNLDSLLLTDSSRAQSRARSVRPRQSVRPVPTEDRQEEGHVAVPETETASALSPPVSSIPAVPQRATEATTFPTPVIPPSTPFPAPPKFNTAQELITALSFTKPDDLPSQRLLTERILFSSPSLPLLPPIPLLTHTITRLLTPSPLPLLPQLLQLLSQLELHRQLLSSQGTAALSIHAATKGPGKLGREARRRLREVAGEKVGEAQRRKWWVLTLHLRKTYIREQLTLNPFVPPDTLLTPVFPSTPSLSTVHLSPLEASELSALKLKCSEQISAVSLWARHFTGTPAQAQASFDIRWPMSPDWKTTVDVVRGYCKDVQELEGVLTCLFGDEEEIKFEPLEVSQLVRPPKLEPASPAQPLLAVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQW4</accession>
    <name>M5FQW4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_17536</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626283.1">
        <property type="nucleotide sequence ID" value="XM_040771291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQW4"/>
    <dbReference type="STRING" id="1858805.M5FQW4"/>
    <dbReference type="GeneID" id="63686353"/>
    <dbReference type="HOGENOM" id="CLU_037460_0_1_1"/>
    <dbReference type="OMA" id="ATHNYFL"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="397" mass="44373" checksum="FC537BEDC70BDC90" modified="2013-05-29" version="1">MPFGEIVIGSPGSGKSTYAYGKYQLCTALHRPIAVVNLDPANDHLPYPCAIDIASLISLQDVMDTSGLGPNGALIYCMEYLEQNFDWLEEELAKLEEGTWVVFDIAGQVELSTNHESLREIVERLQKLGYRLAAVHLCDAHYVTDASKYISVLLLSLRTMLQLELPHINVLSKVDLITQYGDLPFNLDFYTEVQDLSHLSHQLSTQPGGQKFASLNEAICELVEDFGLVGFETLAVEVRAYALRDGVICQWADVSQDKTSMLRLLRVVDKATGYIFAPPPGSHDPSSTQAPDSHTRSTSAPNTDALFSSAFSSLPGPGDVRDVQERWVDERERWDEWEREEWRKEGESVARKKAGRELREKEAEKRAKEQNKPGKPVANAGQEGGFSEMRIRDRTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRX4</accession>
    <name>M5FRX4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626903.1">
        <property type="nucleotide sequence ID" value="XM_040768876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRX4"/>
    <dbReference type="GeneID" id="63683938"/>
    <dbReference type="HOGENOM" id="CLU_2003837_0_0_1"/>
    <dbReference type="OrthoDB" id="2505969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="14616" checksum="E8681044FDFE96A8" modified="2013-05-29" version="1">MSLHFLWTRWDEDRQAGLADFLCENYCQALHIFPTMQLLVIKFQQQQNLTDEDFSRYICEEEEYFSCLVTEPEEDVLTFNYLEMLQSLAAAKSRLAELGFDGFINTTPETWYSGSNNMCQWALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS52</accession>
    <name>M5FS52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_91375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624862.1">
        <property type="nucleotide sequence ID" value="XM_040777007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS52"/>
    <dbReference type="STRING" id="1858805.M5FS52"/>
    <dbReference type="GeneID" id="63692069"/>
    <dbReference type="HOGENOM" id="CLU_010969_1_0_1"/>
    <dbReference type="OMA" id="MALWNDW"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06564">
        <property type="entry name" value="GH20_DspB_LnbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052764">
        <property type="entry name" value="GH20_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678:SF1">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-hexosaminidase bacterial type N-terminal" evidence="8">
        <location>
            <begin position="23"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="7">
        <location>
            <begin position="170"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR625705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="682" mass="75269" checksum="78B2C95B46D3EE34" modified="2013-05-29" version="1">MLAQLTLDRDDDSPAATSYFAQIPSIASFEFSRGAPFLLTAATRVLVDSNYANTGSPSLLDFATIFRQDLLEVTGFDYLPQVSLASDGGLSGIIYLTLGASDYSLYNGQATDEGYEFDVSHQTITIKGSGARGAWWGTRTLLQQAIVSDKMSGFMTVPSGSGWDAPGWEVRGFMLDAGRHWFETSFLTDLCTYASFFKLNEFHIHASDNLWDPNWLYTDLWPELYSGFRFRPANDSANYGVVPQLNESWSQSDFQAMQSSCAAHGITIVPEIDTPGHSLAISQWKPELMLAGNPDQLNLSYPATIPTIQDLWEEFLPWFTSTEISIGADEYPSQYADEYIYFVNDMADYVYARSRKSIRVWGTYEPSNTSSISKNVTIQHWDFPGDTIPVQLLADGYKVINSEQVFLYLDGKTSDGNQFPLSLNESLFWTGAPGEVGWAPNVFSATDESNNTYPGDPGLRGAIFALWEDWGNNATDPLEVYLQLSKSITLFGEKSWAGSGVRSTQLTQEQFDSVYPALNARAPGQNLNRAVKPLGPQGEVFSLNFGGHDFSQGPVGTGVQSVGPPYVLSVTLTPLSGEGTLFRGEDTALLLQNLTFVDVPTNTYFSLPLSLPLGVQSTLEIHATCEYTYLLLQGQGREVYWTTRMDIWGERMQLGNMSFPAPSAWIGEGFEGEIGEVVLRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSF8</accession>
    <name>M5FSF8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SRF-TF-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_57073</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625691.1">
        <property type="nucleotide sequence ID" value="XM_040775412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSF8"/>
    <dbReference type="STRING" id="1858805.M5FSF8"/>
    <dbReference type="GeneID" id="63690474"/>
    <dbReference type="HOGENOM" id="CLU_142009_0_0_1"/>
    <dbReference type="OrthoDB" id="2284405at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000002">
        <property type="entry name" value="Serum response factor b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="73"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="16819" checksum="596957B17B27FE30" modified="2013-05-29" version="1" fragment="single">MSQSSPIQTHAFPPGVQLSPRGSKRTRSDSNAQPPNNGALGGDNSVFQHEVPDDDGVDDDDDEDESPARTKKAGRRKIKIEFITDKSRRHITFSKRKAGIMKKAYELSTLTGTQVLLLVVSETGLVYTFTTAKLQPLVTQPEGKNLIQACLNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSL0</accession>
    <name>M5FSL0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD1</name>
        <name evidence="13" type="ORF">DACRYDRAFT_82699</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSL0"/>
    <dbReference type="STRING" id="1858805.M5FSL0"/>
    <dbReference type="HOGENOM" id="CLU_029061_1_1_1"/>
    <dbReference type="OMA" id="HSPASWV"/>
    <dbReference type="OrthoDB" id="4330at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023352828" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023352827" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="418"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="50"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="417"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="49507" checksum="FF531631F03F6A60" modified="2013-05-29" version="1">MDSALPPPPDAPLAQKVAHAWRTTETKWYPLPLAVGALLLVGLAWKHEYQRRRREAEVTLSGDGEVLKLQGPWQVHVLGALPLRQLSRLWGWLNSHELPLWLRPYGYGFYAWLFGVNLEEMDPADLSAYRSLGEFFYRGLKDGARPIAGTELVSPSDGTVVHLGEIQANRRIEQIKGVTYSLDALLGRGQSSTPVLSPSLPPREGTQDSAFAEINGIPYSLISLMGSPSSKPPNAPHRPATPIKAQDQGDRAIHQPVGEKVHHSVQVAQEMGAQAVTSLGHTVREGNSLFYIVVYLGPGDYHRFHSPASWVVEKRRHFSGELFSVNPWLVSRLPNLFVLNERVALLGKWRHGFFSFIPVGATNVGSINISFDTDLRTNAHSAPPVGTFVEASYSSASALLGGWPAVKGEEMGGFALGSTIVLVFEAPQRWEWSVKPGEKVRVGQALGDHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSL7</accession>
    <name>M5FSL7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_70037</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625811.1">
        <property type="nucleotide sequence ID" value="XM_040775915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSL7"/>
    <dbReference type="STRING" id="1858805.M5FSL7"/>
    <dbReference type="GeneID" id="63690977"/>
    <dbReference type="HOGENOM" id="CLU_001570_20_0_1"/>
    <dbReference type="OMA" id="ITANDFH"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF12">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067191" evidence="11">
        <location>
            <begin position="28"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="24800" checksum="F1378FE5EE9176DF" modified="2013-05-29" version="1">MAGQETMTYTLRVFILAILHNPAVAKAAQAQLDSICGSHAPSFEDREQLPYIEALIKETMRWRPVAPIGVPHLASEDIEVQGFLVPKGTLFIDNIWSQSRDPALYPNPDQFDPARFLDATGCLASPIPDAHQLGFGRGRRICPGRDFAINGIFIAAASLLWAFDFEWAVDVTGNPVMCGTLEMEDHSVLATVRPFEMKVKPRREGLDEKLLELLRERDANLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU40</accession>
    <name>M5FU40_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_108522</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628088.1">
        <property type="nucleotide sequence ID" value="XM_040768670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU40"/>
    <dbReference type="STRING" id="1858805.M5FU40"/>
    <dbReference type="GeneID" id="63683732"/>
    <dbReference type="HOGENOM" id="CLU_702123_0_0_1"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="291"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="393" mass="43858" checksum="0AF97DE396E3AC02" modified="2013-05-29" version="1">MTSRWMTALQSKVLGYLVNTYPHLLNLGRREEQTTQRSKDRLRKMIAGMSNHGPGDLSTRYVAIDCEMVGVKPRGASSLARVSIVDYEGRILLDRFVKQTKKVLDYRTKWSGVRPADLIGAPSFEEVQATAIQLLDKRIVVGHALPNDFRALRLSYPSQYTRDTQRYVPLLHRGVGKSLKRMIKEVFGMDIQAHEHDSVIDARASLALFRLYQSEWEKDLSFTHFIASSVGTNYSQESNGEDVTSPLSALQQDSRHVPLRDCGPSADISSQDGNETPVATSSSSDLVTCNAPNKILGDLAVYIIPAKLTADQFVELSRTIEGNGGRLTSQANAADVILTAVGSMKRLERHISIHAPRKAPIIRVEWLLESTNAQRRLPYRNFVAVPELVLRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUA1</accession>
    <name>M5FUA1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial proton/calcium exchanger protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Leucine zipper-EF-hand-containing transmembrane protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_25491</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LETM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623709.1">
        <property type="nucleotide sequence ID" value="XM_040774183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUA1"/>
    <dbReference type="STRING" id="1858805.M5FUA1"/>
    <dbReference type="GeneID" id="63689245"/>
    <dbReference type="HOGENOM" id="CLU_008958_4_0_1"/>
    <dbReference type="OMA" id="QNEMIAD"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="14">
        <location>
            <begin position="252"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="38"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="474"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT96811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="698" mass="78249" checksum="45A7D097832B445F" modified="2013-05-29" version="1">MQNVLRHRGLATPYRLSFQSHAVRPIALRPLAGVRWNSTSLDKQPGRTPPPPVATPGAQREPSKSRLTDPAPRPAPVQASTPQPPPPPQAGLNGSPAYAPGTTPSTSPTKPISSVEAKEQLADEHVSKEIADHKADKPSKELAEPNKPLLARAWAWLKHEANHYWSGTKLLGKEIRISARLVSKVLGGTKLTRREHRQLKRTTNDLLRLIPFSVFVIVPFMEFLLPVALKLFPNMLPSTFEDKFAAEEKARKLLRVRIEMAKFLQDTLRETGVKGAAKIADSEEFKEFFRKVRSTGEEPTREDVIHVAKLFNDDLTLDNLSRPQLVSMCRYMNVNAFGTDNFLRYVIRQRLGSIKRDDQLIDDEGVDSLSTKELQEACRSRGVRTIGISPATLREDLNQWIELHLTNNISGTLLILSRAFAMGEKGDDVVKSLEATLASMPDHLLNEAELDVSGDRGSYQQKLEVLQQQEELIEDEAEQEQEEEDARRKKRELEERTKREKEAQMAQSMLPESELVEEEDARMTTEQLSELGEALSILSAQSSVLKERAELQALMKEHEITEVPEDPSTLSSEDRASLSLAKRIKGMLKKIDAQLTEYDTKVGNSLQLISCTSQGMISINDLKQALRVIKHHPDEETIEGLVGKLDVDKDGFVVLEHVLELARGESLGIVVDEHAKDLMKEGKELVADKPRKEDIVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUN5</accession>
    <name>M5FUN5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">DACRYDRAFT_23500</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 26">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626866.1">
        <property type="nucleotide sequence ID" value="XM_040773268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUN5"/>
    <dbReference type="STRING" id="1858805.M5FUN5"/>
    <dbReference type="GeneID" id="63688330"/>
    <dbReference type="HOGENOM" id="CLU_000524_5_2_1"/>
    <dbReference type="OMA" id="CYDRNDS"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="20">
        <location>
            <begin position="74"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="253"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="516"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="614"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="23">
        <location>
            <begin position="704"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="17">
        <location>
            <begin position="779"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="1153"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="943"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EJT99968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1258" mass="141872" checksum="EDE5F955E2218C5C" modified="2013-05-29" version="1">MSTDYDAQGYDPYGAVGDTKYADGSNYQPYADVRMGVDSADGLQTEEGYEGIPEGPLSQEDCWQIITSFFEEKGLVRQQLDSFDEFVQNSMQEVVDESGELILDQANQHSGRELDETKRYELSFGQIYLSRPSTMEPDGSNLPIFPQEARLRNLTYSAPLYIDVKKRVLSGRENPEDVNGEMIWESQNTDADKEIHKIWVGKVPVMLRSTFCILSGLSDGDLYDLNECPYDQGGYFIINGSEKVLIAQERMAANHVYVFAKAQPSPISHLAEIRSQVEKGGKQISLLQIKMTHRNLEKSTGSLMRAQLPYIRNDIPVVVVFRALGIVPDRDVLEHICYDPEDHAMLEMLKPCIEEAFVIQDREVALDYIGRRGTTTGLSRDKRLRYAQEILQKEMLPHISTQEGAESKKAYFFGYMVHRLVLAALDRRELDDRDHFGKKRLDLAGPLLATLFRMLFRRLTKDVYRYMQKCVETHREFNINAAVKPATITNGLKYSLATGNWGDQKKFMQAKAGVSQVLNRYTFASTLSHLRRTNTPIGRDGKIARPRQLHNTHWGMVCPAETPEGQACGLVKNLALMACISVGSLSQPVVEFLEEWGLEPLGDQTNETITATKVFVNGVWMGIHRNPQHLVETVRTLRRSDGISSEISVVRDIRERELRLYTDAGRVCRPLFIVNEGTQDLVIGKKEINCLQNRVDDEGQPYGWSQLVSSGMVELLDAEEEETVMIAMTPEDLEASKTKRGTGYISNEPQNAAVRIKSIVHHEHWTHCEIHPSMILGICASIIPFPDHNQSPRNTYQSAMGKQAMGIYLTNFQVRMDTMANILYYPQKPLATTRSMEYLKFRELPAGQNAIVAILCYSGYNQEDSVIMNQSSIDRGLFRSIYYRSYTDMEKSTGVVPIEEFEKPHRDTTVRMKHGTYEKLEADGLVAPGIGINGEDIIIGKTAPLPPDSEELGQRTRTHTRRDVSTPLKSTENGIVDQVLLSTNENGVKFVKVRIRSTRIPQIGDKFASRHGQKGTIGMTYRQEDMPFAANGITPDIVINPHAIPSRMTIGHLVECLLSKLATLIGNEGDATPFTDLTVESVSSLLRNKGYQQRGLEVMYHGHTGRKLQAQVYLGPTYYQRLKHMVDDKIHARARGPVQIMTRQPVEGRSRDGGLRFGEMERDCMISHGVASFLKERMFDQSDAARLHVCDICGLASIANLKKQTFECRACKNKTRSTQFYIPYAAKLLLQELQAMNIAPRMYATSTGRTRQSAMNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUU1</accession>
    <name>M5FUU1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_90083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626921.1">
        <property type="nucleotide sequence ID" value="XM_040776944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUU1"/>
    <dbReference type="STRING" id="1858805.M5FUU1"/>
    <dbReference type="GeneID" id="63692006"/>
    <dbReference type="HOGENOM" id="CLU_2209931_0_0_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11709" checksum="FA321A90F5206CD8" modified="2013-05-29" version="1">MAFQSLYLTLSSLFLSFSALSILPIPLLPSPSAPPSWLRLTLPALYLPYALAVASSRITLGHHTLPQVLVGALWGIIFAAAWWSLWPSMKTEVEEKVLPHLGGWVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV06</accession>
    <name>M5FV06_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein transport protein SEC31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein transport protein sec31</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_23938</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">COPII-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626292.1">
        <property type="nucleotide sequence ID" value="XM_040773471.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FV06"/>
    <dbReference type="GeneID" id="63688533"/>
    <dbReference type="HOGENOM" id="CLU_003033_2_0_1"/>
    <dbReference type="OMA" id="WLERPCG"/>
    <dbReference type="OrthoDB" id="542917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000193">
        <property type="entry name" value="Protein transport protein SEC31, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009917">
        <property type="entry name" value="SRA1/Sec31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07304">
        <property type="entry name" value="SRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="7 15" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067211" description="Protein transport protein SEC31" evidence="17">
        <location>
            <begin position="30"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="272"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="SRA1/Sec31" evidence="18">
        <location>
            <begin position="1350"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="523"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1036"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="563"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="645"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1041"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1096"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1122"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1139"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1151"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1183"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1209"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1270"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1302"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="1331"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1344"/>
            <end position="1356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF07304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJT99394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1491" mass="157068" checksum="A0E7DA13697B1C28" modified="2013-05-29" version="1">MRLKTIPRTSTFAWSPVSVLPLLATGTVAGALDENFSNEGRLELWEPDLHTAQHDKPTGSVVTTSRFNRLAWGNVSIDHPKGLIAAGMESGELGIWDPEKIVQGLDPAESLILSNKKHQTSLRGLDFNGLQTNLLASGASAGEIYIWDLTNPTKPYTPTGTAAPSTKLDLITSLAWNSSVAHVLASSSSTGYTVVWDLRGKREVVALAYGGGAATGGGAVAGGMEIGRRRGMSDVCWHPENPTRLVTSSEDDTSPIIMLWDLRNSRAPEKILTGHEKGVLSVSWCKQDADLLLSCGKDNRSLCWNPQVGEIIGELPSSHNWAFQVDWCPRNPDFLATASFDGTIGLHSLQSTNEAAAAPLAAPVQADGADIFDLPSTTEQPKTALSLKQPPKWLRRPTSSSFGFGGKLASVHNSTQAVQHGHGKGVVKLRTIVTESSILERLEKLIQAEAEGPAALQSFVEARTGESAPDGDLKETWRALSSLFRVDNRDELITLLGFSKEEVKERVKEAVEKLKIVPSVALSTDREASEALSEPTVTFAEPEHEQIEESEGPQDTDPEDTTEAPSETSVGATSIGTKATAAQTEADTETTEPSLFGEDIGAVAPGAAGTPAPADPADFFSSMGTIRSALPERVLYPHQNYANDSSQAATIGSRSSSIADLNDPPSRAANTFKIYPSEESDVDKLVTKALVLGDFDSAVQLCLGAERFADAILLAVKGGPELLASTQKAYFQKRVTELPYLRLFQSIVSDDLADIVQNADLREWKEIFVVLCTFAKADDFSGLAEQLGQRLEFQGRLLGEDEKGKKALRKDATLCYLAAGKLEKVVGIWTEEMKEEEDAAAQSEEGAKLSTYDAHASALQTFIEKVAVFRGAASYVDTELTQPTESAAVAESGARTYKLAALYDRYYEYADLIASQGLVKESVTYVAMIPSDYRGVPGMEVQFDVIRDRLLQAAGVKDNAALRAKQQASRAAVAAADVGYFPKGLSAAPVQPAPAIPAIPAQPAATSAYAPYGYAPNGASAGPVAANPYAPAATGYQPSGGPMPPPKSQPYPPSAPMQYPSNNYANAPYGQPAYQPSAPSSIVPPPPPVIDEATGIPPPDITPGPPRGSFIKREATPGWNDAPTVASARRAASAAAPASVPPPITAPFPNSPVSAGLTSPYAQPMHQTASLPPPPSRGSTLPPGQPGGLPPPQRGQALPPPRNTASPRLPGPPPRGGPPGPPPGVAGRPFQPPPPGRGPGAPGYPPQRTSSPLAQGTPGAPPMRALSPPQQGPPRMPPPGQPRMQGPPPGRPANGAMPGPPGQRVAAPPGAPGQQWPSVPAGAPPVQGGPYGPPPGAHPPAPPSQAMSPPSGQPPQLSRSGTPAGGPPMPAAAQAPKYPPGDRSHIPSALDPIFQVLSQDLAQLKATIPPQQKRLVDDTERRLNNLFDALNCESLTSPVVQQLHQLIAAMQARDFHSAMNVHVRLLTSGTASDNVAIWGPGIKQILNRMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV78</accession>
    <name>M5FV78_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_23637</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626412.1">
        <property type="nucleotide sequence ID" value="XM_040773322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV78"/>
    <dbReference type="STRING" id="1858805.M5FV78"/>
    <dbReference type="GeneID" id="63688384"/>
    <dbReference type="HOGENOM" id="CLU_013783_3_0_1"/>
    <dbReference type="OMA" id="EKHAWVE"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067340" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="20"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="204"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="563"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT99514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="586" mass="63179" checksum="F5B9CE6733402664" modified="2013-05-29" version="1">MIFIQLLFWALTFSGSALAWQSFLVKESVSVIPRGWTTSSRAPPDHLLRLQIGLRQADPTSLYDALANISDPRHVQYGQHLEKEQVEALVRPHPDASESIEAWLSHHGIPAGSVSRNGAGDWLSIEVPVHKAEHMLDAEYRIFEHEDGSSIVRCSSWSLPADLYEHVEFIQPTTMFARLKPQRSFVHSVSPGIVLANPIDCSHYVTPDCIKELYGIGSYRPNSSAPNHLGIAGYLESYANVNDTTFFYQEFAPKAFADDFTFSVELINNGFNDQSEMAASLEGNLDVQYGGSLSFPIPNTYYSTGGSPPFNPSSGTPQNTNEPYAEFLSYILNKSNSELPTVLSTSYGDEEQTVPYSYAVSVCNLFAQLGARGVSVLFSSGDGGVGDGKGPGQDSLTCISIDGNYTPMFLPFFPATCPYVTAVGATSGVPETAASFSGGGFSNYFSRPYWQEGAVNAYTPQIPSSYSGFYNASGRAYPDVSAQGDNFIIRQSGNLTTGFGTSCSAPTLSSIIALLNDFLMARGKAPLGFLNPWLYIIGSTGFNDIVTGTNPGCGKNGFSAAVGWDPITGVGTPNVTRLMSLLSLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV92</accession>
    <name>M5FV92_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627081.1">
        <property type="nucleotide sequence ID" value="XM_040768768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV92"/>
    <dbReference type="GeneID" id="63683830"/>
    <dbReference type="HOGENOM" id="CLU_1660700_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="159" mass="17759" checksum="F311308454393719" modified="2013-05-29" version="1">MPPHNKKSVTLGVPTDLPEKVSGNQPKPTTKRAHPAPKQQQQQQPSMPKAPKVPDKCVPETQDKPDNPMKQAKNAVDLTKEPTKVSWKEHIKELEEQLAKKGFDEVKVQLDKVKKKVPIIQDNSLMIPKPPGQAGCKTQIKDSKVIVRAPAHCLVKRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVE5</accession>
    <name>M5FVE5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627151.1">
        <property type="nucleotide sequence ID" value="XM_040768782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVE5"/>
    <dbReference type="STRING" id="1858805.M5FVE5"/>
    <dbReference type="GeneID" id="63683844"/>
    <dbReference type="HOGENOM" id="CLU_014664_0_0_1"/>
    <dbReference type="OMA" id="RDLWIEM"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932">
        <property type="entry name" value="ATPASE EXPRESSION PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932:SF44">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="826"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="837"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="913" mass="102150" checksum="BD9089A282FE57F9" modified="2013-05-29" version="1">MLKNEMAAKMEAVEWHTRDLPAYEEEDFERVWEALVSNPLGDGPEKKVVPAIGSRMRELEIVQGLYQRLLTASGAEKSKSEQAPHSRLDLFTDYFPLVGSIPLSQAEESNILRRSASAIQQELSQSSTAQKSEPAQPTSGETSKERWRTLLFLAAGSVPRQRTPDIRNELRASYPIALHRIRTLVANAHGSENSEMPWDASPPGVRLPVASREEWSVLLAAAACFRDRASVKEVFYLMRFSGFPITDALRREVLEAFARQGWVEDVQDLTSYMNRTLPDAAQIPQDYIVKALSYSGQLARAITHLHALENSNTPASQSTYACILSSLLSRRGIGAARDLTLAWELFAHMRFVAHPVPSREIYTLMLRACGAGVRPQPERAQDLWTEMTQDSAHSPTTEAYNALIYVLARSKSTALEAFRLLGELIQLSRDTLPSPTGPVLRPDMNTYLALLESAKRLGDLPRARWILAEMLRDAQRGGVKPDERTMVGVFQAYAAYEVPFVRAKVKVVDGTQAAQKEENIEAQKEAVEKENEPLPSAPVQVDTLTFTPVVPQSHAEVIREVEALMTRILEESAPQDPSLPSPTETPLFAEVVLTPRLWNSFQSVHWAHSSLDTAMARYHEQATNRFEPNAWTYLYALERCAYPRKEERSKALDFARLVWVDWLTWLAKNGRGLLAWDLSKELGTLSGAKGDMPPPAALTGSAAARVAERCWAAMIRVTALTDQLDESLSLVRVFMKRFPPVSLHARPQTPGEALAFRPALRSSQAERSLSESDDAVPPVLLFRDVELLHHRLVARGRFEDVGFLRWACKAYVGGLRERRMKASEEEKLMLREPAGPEPEEEEEVESIGEPAAWHSDEIQKNLGMGQDMTWEQPAAMGSKSIPPHLIERQPHQWASGTPQASPWFPSSRMQARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVG9</accession>
    <name>M5FVG9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624224.1">
        <property type="nucleotide sequence ID" value="XM_040774018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVG9"/>
    <dbReference type="GeneID" id="63689080"/>
    <dbReference type="HOGENOM" id="CLU_2605975_0_0_1"/>
    <dbReference type="OrthoDB" id="10329718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="8884" checksum="992A90AF979E7B14" modified="2013-05-29" version="1">MFAYSSSEITPNNTDFAELDITARASHLHLFDGLSNADNDEIVSKIGQEYLWLGESEDGRSVEISSEKLTPLQLRKAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVP6</accession>
    <name>M5FVP6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627301.1">
        <property type="nucleotide sequence ID" value="XM_040773195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVP6"/>
    <dbReference type="STRING" id="1858805.M5FVP6"/>
    <dbReference type="GeneID" id="63688257"/>
    <dbReference type="HOGENOM" id="CLU_715761_0_0_1"/>
    <dbReference type="OrthoDB" id="3357029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="386" mass="41243" checksum="116E3E9903CC1E2F" modified="2013-05-29" version="1">MAVAVPAVIDPSYSFSLRTFGVQPVCKAFTTGCNLVKNPGPWGDQTLNCSGAGYPQLPYSPFNATVDATATSASENSWIFGLADNVLGVGDTQATSFTPEDYTNPAQFLLQLAWIGFGPNDQPSCDAITEWPEPEALDHPDGVVFSSSALAVFADCNLTWYNITLRSSDGLYNVTDKELSDTLFVSVLGAPLLYQLPAQHLASYLQSVALTQNDSLNLMVLLAAELGRQAMSFAAGFLIPDDSYDEELIKARLFGQYPVAPVCVIIVLLAVFILATILVGLWVILDSHTPLVSPTVTEHPSAGINKGDPTLAELAHLRLTKSTAQILNTTSDPEPSFQTEVSKLFGPGGRSLAGGVGIGVVHRQGFRAVEVYNLDHELDSKDAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVX3</accession>
    <name>M5FVX3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_68019</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627406.1">
        <property type="nucleotide sequence ID" value="XM_040775864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVX3"/>
    <dbReference type="GeneID" id="63690926"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="MGCANTS"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF79">
        <property type="entry name" value="LACTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="63"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="550" mass="60658" checksum="95D7BE1745ED34D7" modified="2013-05-29" version="1">MALSPTEVHVDSSKLDNTSDLAKIDYNGATDVVKQKQETLREAFDADPGIPFFSPRALQFAYIVAVVLCCSGDAGYDGTVMSAISSMVQYQQYFNLQAASSKTGIVFGIYTIGQIASFLTCATLPDWFGRRWGMLLGNLCLVTGSVVTANVNAMPMFIAGRFLTGLGTSTAGVSARSYLAEITSPATRGRYVGLLNSFFYVGQIIASGIAIPTGRYSDNMPWRAPIYVQGLPAVINVVLVLGLPESPRWLYTNGKTQQATQILAKYHSKNNDINSPMIQLQLAEIEESISPDGSDRRWWDFRPLFKTRADRYRIWLVTLVAAGSSWAGNGLLTNYLTILLNQAGITDPDRQRVLNFVNSVTSFIGALLGTASVDYVGRRTIVLTAIFACGTGRQRNARVIIAGLLSTAGTNVAQANAGISFIFLFMVFFSYGWTPMQALYPVEVMSYEGRAKGLAWYTLISQGTNCVNTFAMPVALANIQWKTYIIFGVFDFCLLGVVWYYFVEPKQLTLEEMDQVFASDNPRLTSLELQRVAKERRRTLKLRHMEKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWS3</accession>
    <name>M5FWS3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_81072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627751.1">
        <property type="nucleotide sequence ID" value="XM_040776490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWS3"/>
    <dbReference type="STRING" id="1858805.M5FWS3"/>
    <dbReference type="GeneID" id="63691552"/>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="54"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="473"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="55628" checksum="0CF1AB596AB91D9C" modified="2013-05-29" version="1">MADIDFDAEKQAALKRTGLNPKAKKGWRSFIWDHDTDQKSPEEQRLLVKLDMTILVYACLAEFLKLLDQQNLSNAYVSGLKTDINLDGNSYNVANALFSIGYAIGQIPGTLLLQKYRPHHVLPLFEVIWSIATFATAAVKTPGHLAACRFFVGLAEAPFFPGMLVTLAAWYTPAELGKRSSIFFVMAQVGSFFSGYLQAACYNLTGVGGLAGWRWLFIMDGVMSLPIALVGFFFFPDSPARARGWWMTPADKQLAVDRIARAGVGKNPGFFDWKLIKRAFSTWHWYLFVPGYVFFGLGTQAATTWFGVWLQAEGYSVYLRNIIPTFTNLVTLVAVLIWGWVSDYIENRPLIMIIAIIYGIFPLACLSVWDIPNGLKFFSYLTLGVEYITPLFFTWANEVNRQDDGVRSFIVASMNCAQYAMAAWVTILTLPASKAPKFSVGYQSCAAFNAIAVIIIAAIWYWDRRDKARALPEDSEIDPTIQGAEEGSEKDTKYLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWX1</accession>
    <name>M5FWX1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_71638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT97951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040775950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWX1"/>
    <dbReference type="STRING" id="1858805.M5FWX1"/>
    <dbReference type="GeneID" id="63691012"/>
    <dbReference type="HOGENOM" id="CLU_002477_0_0_1"/>
    <dbReference type="OMA" id="MCFEMHG"/>
    <dbReference type="OrthoDB" id="271862at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF76">
        <property type="entry name" value="KH DOMAIN-CONTAINING PROTEIN YLL032C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="243"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="496"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="565"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="648"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="961"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="961"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1046" mass="114783" checksum="BCB9B8006C20982F" modified="2013-05-29" version="1">MDLYTTSFTYPRHSPTFSPTYLDANVPPAANLPIPQSHVRSQSVEAYPAGPQIAQAPAQGQPPQQATQAGVPSQQTHQTSPRSSLEVGVDAVQRVAMDAMAAHGCLVTFTKADPGKGWNFHLSGGYQQVMASRGMIIREAPLNTRSAIRVPRSELLDSTASLSLKPDVRRRLDEITAVTQAHISVVHSQPSTGPGAVSDVSGGATTWSGLETEKTCDIVMVGPEESVDMARVRILVMLDEISGLHAESCEIDYKLHAIIAGRKRAVIQSIQEETATNIYFPTPYSGVVGSRAASQAFAQVQMGPHGIPVQQSPMTPARVNRNVIWITGEFFGVQRARDMLFQVSMHKVRSVISRDTAMLPRKLDWMLTERMDDLKQIMSDNGAFINFPPVGSQASLISVYGDNRVCIQRTIRSVMQLACQFYIASFWLLPMTFDAMVPSQSINPAQMPAVLKRISNQSGAEIVFKSNCFEMHGLEHEVRAAVQIVLELDIVRNFHHEIRFQIELANDQREFISGKKNGKINKIMKMANVKIKFETFNDHNFLIDVAGSDQGALQGLTMLQEELPAEISFHVPEVYHKRIIGVGGKNIQKIMKKYGVYVKFSNAEEFAQLGGYMDNEDNVVARTPAKNASNLENLKASVMELVNPKDKDYTTETVSIPRRYHRTLLGDKAIFIHDIEQKTNSLVRFPDKETASDIVSIFGPESQVHIAAAMLLEHVPFEADFYVPPSSQLENVAVSADFLAFTERVKRDLHIAIFPPAKPGSGDEVSFKFRCQRSNVDFLPAAREALEAFLVSRHVGVFQADPAQQVGRGDSFADAFAHFDSKLLATPNTNEGDISRPQEGFADRRLRLAASTPDVKALFNQTNFVYNIPENESYPAPGYQPPTHFGSDAHLPPPVGNEYWQAMPSLMGVNPGLHRRFGSIDTPHAGIAQTMRTGDDVVKRGSDSLLEAKLKDYVNKPRSLSNRAQSLDMSSLASISRSGSTTTVRAASPSGSITNSTPPSASTPYFPSVTPTAPGAQLVRSVPRAPVGVDDVTKALGQAQLDPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWX2</accession>
    <name>M5FWX2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627816.1">
        <property type="nucleotide sequence ID" value="XM_040772949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWX2"/>
    <dbReference type="STRING" id="1858805.M5FWX2"/>
    <dbReference type="GeneID" id="63688011"/>
    <dbReference type="HOGENOM" id="CLU_1085951_0_0_1"/>
    <dbReference type="OMA" id="MNIDHIV"/>
    <dbReference type="OrthoDB" id="3359616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067261" evidence="2">
        <location>
            <begin position="20"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="256" mass="25775" checksum="1BA51FAFB2179A85" modified="2013-05-29" version="1">MQSAVVLAALAAFAGSALAQNTLMVDDNDPLIDYEPSGEWTVLNGSTIGAFGGTLHFTGLSGNTSSPTSGVAEATATYTFSVPATGFLWMGYQRSDAGLYQICFDCDGNNPITAQVDALNTTSTGSDFPVTLYSISTLSFDIHTVVISNLFDSRHGSYGQITIDAFELTGVASNTSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTPSVPTTPIAPPISPLSSPTAAPPKSGAMARFGVPASAVALLATLLAGALML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWZ4</accession>
    <name>M5FWZ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent RNA helicase SUB2</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">ATP-dependent RNA helicase sub2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">DACRYDRAFT_22801</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627841.1">
        <property type="nucleotide sequence ID" value="XM_040772955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWZ4"/>
    <dbReference type="STRING" id="1858805.M5FWZ4"/>
    <dbReference type="GeneID" id="63688017"/>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="YAHVEPK"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000168">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase 56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="90"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="293"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="17">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00040402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EJU00944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="49997" checksum="AA29F866E7EED01D" modified="2013-05-29" version="1">MADNAEELVDYDEDLTINEPATAPAATAVSTTNGHGATDGAGEEDVEDEKKGFGTIHSTGFRDFLLKLELLRAISELGFEHPSEVQQECIPQAVLGMDVLCQAKSGHGKTAVFVLATLQQLEPVDGEVTVLVMCHTRELAYQIKNEYGRFSKYMPDIRTAVFYGGTPIKNDIELLKDKNRCPHIVVGTPGRLNALVRDRVLNPSTVKHFVLDECDKMLEQLDMRRDVQEIFRATPHHKQVMMFSATLSKEVRITCKKFMQNPLEIFVDDEAKLTLHGLQQHYVRLEESQKNRKLNDLLDTLEFNQVCIFVKSVARANELDKLLVECGFPSICIHSGLPQEERIKRYQQFKQFEKRILVATDIFGRGIDVERVNIVINYDMPTDADSYLHRVGRAGRFGTKGLAITFVANDADAEILKQIQSRFEVAIPDLPAEIPAETYMAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX78</accession>
    <name>M5FX78_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627941.1">
        <property type="nucleotide sequence ID" value="XM_040772982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX78"/>
    <dbReference type="GeneID" id="63688044"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OMA" id="LCLMYAP"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="260"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="450" mass="48518" checksum="15332436CF233AAD" modified="2013-05-29" version="1">MAEEAAEEIIALEVRDDWEATTPQTDQNGTTGNSLSAETKEQPYVHIIPDGGWRAWATVAGSFLMSMCTFGYINAYGVYQAYYVQTLLPSYSPSAISWIGSLQTCLLFLCGLVTGRLFDAGNFRPMMIGGGVLVVGCIFALSAVQVDGYYQVFLSQAVGQGLGLGIVYLPSLAVLGQHFQKRRSTAMGISVAGSSLGGIVFPILLNNVFQSRGFQWGVRAMGFFQLGTMIIANLLMSTHYHPHQKAMKPPSPLKLLRDVPYLVAMVAAWTIGLGLYFVFFYIQLYAETVGISSTVAFYTLAMINAASIFGRTLPNLLADKFGPITVLIPCSVVTGAIVFAVLGIKNVGGLVIVCILYGFWSGAYVSLVGPMYASMADSLSEIGLRMGLAFAFLGFSALIGTPIDGALLGDGPDYTWWKAILFSGVTMLSGCALLVVAWVLFRKKVNKQWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXG3</accession>
    <name>M5FXG3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_111151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625074.1">
        <property type="nucleotide sequence ID" value="XM_040769181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXG3"/>
    <dbReference type="STRING" id="1858805.M5FXG3"/>
    <dbReference type="GeneID" id="63684243"/>
    <dbReference type="HOGENOM" id="CLU_093191_1_1_1"/>
    <dbReference type="OMA" id="LWEEVGF"/>
    <dbReference type="OrthoDB" id="48036at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052436">
        <property type="entry name" value="LTO1_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532">
        <property type="entry name" value="GEO13458P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532:SF1">
        <property type="entry name" value="ORAL CANCER OVEREXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="3">
        <location>
            <begin position="46"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="193" mass="21212" checksum="992246EECACA4166" modified="2013-05-29" version="1">MDVDLESFQRHQAAPSGRSAPQQPAVDVSLELDDLGNLEQHFYNQGYHDGYQHGTIHGLIDGRQLGREKGFELWEEVGFYEGFTSTWSRLISLPSTEGEGTRTRAAQSAQRLLALVARFPTTNPTPEPTPPGEEEHPDVLSDEHATVPLGEDMPALLARMRAQYRALCAALGVRPRMAVAGSAGEEMGRKLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXS3</accession>
    <name>M5FXS3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629730.1">
        <property type="nucleotide sequence ID" value="XM_040772546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXS3"/>
    <dbReference type="GeneID" id="63687608"/>
    <dbReference type="HOGENOM" id="CLU_980124_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="284" mass="32511" checksum="49EDC6B8EC6C5EDC" modified="2013-05-29" version="1">MRRRPVVPLQRVPCRPLDNALIPRARRRSTTFYPSETHETERRRPAWTFSVQDVEAVSWTQLNYQTSGETNRDLHSLLDGLFRRGQEMADLWMMAEKLESCTFHDIPVLDDPFSSLPRTPHSLHSLLLAMGGTWHTNPSVQLLDLVEGVHLLNLSLQWLFHLEDEQIQKGASDILHCEQDGNMKMQSYLRTDAILEDDGLLPPLEHGSMQLGHSDRRGHCAFEPRGLDMWALHDSMLLRPQDLKKHKDCGWSMCPGSRIDSLLAFMSLRSSNTTMALMNGHQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY43</accession>
    <name>M5FY43_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_53089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628356.1">
        <property type="nucleotide sequence ID" value="XM_040775149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY43"/>
    <dbReference type="STRING" id="1858805.M5FY43"/>
    <dbReference type="GeneID" id="63690211"/>
    <dbReference type="HOGENOM" id="CLU_008455_11_6_1"/>
    <dbReference type="OMA" id="PEYRMEV"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF173">
        <property type="entry name" value="MFS-MULTIDRUG-RESISTANCE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="42"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="483" mass="53987" checksum="4510A6A4BF7F2DA4" modified="2013-05-29" version="1">MVDEERPPEVLNEKLSQFLVHWDGPDDPENPKNWSKLKRWYVTVFGSLLVFNASFASSAPSGILPQLIVDWNMSTEIATLLIAIFVLGYCVGPIFWAPLSEAVGRRPIFIIAFTLYTIFQVACAVAPNTGALIAFRFLGGLCAACPLTNAGAILADMWDPDNRGRAIAFFALAPFAGPALGPIVSGYMTVAGVHWRWLFWVLTFFAAACTIGIVFTVPETFAPTLLTRKARALRKKTGDTRYFSALEVMEKNPRRLAYLIFGRPFKMLIREPMLFFITLYMSFVYGCIYLLFEAFPIVFTLGHHMDEGTSGLMFLPLFLGGCTGAASYLFLFNPRYEKHIERFAPKAVPPEYRLEMAFIGAPIFAIGFFWFGWTSFPSISFWSPMMATSLLGLGVVLIFLSLFNYIIDAYLMVAASALASSTIVRSLFGAAFPLFATQMYNRLNPRWASTLLGCLAVLMIPIPFVLRVWGARLRRKSKYAPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYD2</accession>
    <name>M5FYD2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_24564</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625459.1">
        <property type="nucleotide sequence ID" value="XM_040773738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYD2"/>
    <dbReference type="GeneID" id="63688800"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="MSWFGQF"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF70">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="58"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="60004" checksum="92D02E2F4D03F007" modified="2013-05-29" version="1">MSASVHEKPLSPEHEESSDQLEPVDPPKEGELTSRLAAAYQYGRPDPFGKGYLRMYLFCSLVYLCSTMNGFDGSLMGSINALPNYTNYYGLPSSGNSSTGIVFAIFFVGQMVGALFIWLADWRGRRLPIFLGCIGVLIGTIVTSTAKTLGVFVGGRFLLSFFATWATTSAPLYMIEMAPPLYRGVIAGLYNTLWYMGSIIATSAVYGAHLHLSWDGELDWRLPLWLQMLCPAIVAIFIWLCPESPRWLIGAGRSEEARQILVKYHANGDENHPLVALEMDEMTESLKHNPMTSWRNFFDLRVLVKTKGRRYRLLLDIAFSWFGQFSGNNIISYYLPHLLDNVGITDVNTQLLLNIIYAIIGWVFAAAGTRFHDVFGRRTMFLGSIAGMIVCLAITAGTAAGYVHTGSQQSSDASIAFIFIFGAVFALAFTSMQPIYPGEVLSNDMRAKGMGIFQLTAGVASFVNTFAAPVALNNIGYWFYVFFVFWDCFEWIIVYFFFVETKGRTLEELDEIFESDNPCKASLKPIDIPISDEKANRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYG0</accession>
    <name>M5FYG0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_108102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628456.1">
        <property type="nucleotide sequence ID" value="XM_040768590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYG0"/>
    <dbReference type="STRING" id="1858805.M5FYG0"/>
    <dbReference type="GeneID" id="63683652"/>
    <dbReference type="HOGENOM" id="CLU_009024_1_0_1"/>
    <dbReference type="OMA" id="NEFIPPW"/>
    <dbReference type="OrthoDB" id="9971853at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="620"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="760" mass="85806" checksum="8140A77EB43D9377" modified="2013-05-29" version="1">MVAINPNHHPSLSEDYEPGSTSSTAHDWSLPIRIQGAHFVDPYNRVLNLRGVNLSGASKTPGDHDPAHFLDENHWRGVSFVGRPFPLEQADEHLARLRRWGLTFGVFPLSTKTRLTSVVRLNVTWEAIEHSAPGEYDHDYLTYLYSLLSKFPAYGLVAFVSMHQDVFSRFSGGSGAPAWTLTSVGLDLDALEETGAAYLEGVRHPGKSEEDRGTWPTGYQKLAAATMNTLFWAGDTFASKLKVQWQGKEVGAQQFLQDRFLAAWEVLVQRLAPLPAVVGFQMMNEPHSGYVENHIHTWDYNTDLHLWAFPTPLQSMALGAGHPQRVAYYTRSFPFPTRQSGSKLINPKGRKCWREDGPTEGRCVWEMHGVWGWERGRGEAVALRENYFMWHPTTDKMVEWYEDFYFPFAKRWSERMHALSGGEKLIFLEPIPNEFCPPWPEEFRPKNFVYAPHWYDLNALFKKQFGNVSVNVQGLSRGMFLLKALYWGDKGAKENYAMQLRNVVDSVSAAGERPVVVGECGVPMDMNNAHAFKTGDFTWQSRMLDALISGLDSARASFTLWNYNPGNTDAQGDRWNGENFSFYTLSARALSSSSEFKDSALAQTNPELDDGGRVLSSLVRPYPAKVAGIPLSYSYSTSTGVFELTYASPAHAGAELDLGRGRDGWVPLDHPAIMARETEIFLPLLLTQGREVKVEGAWKWVYSEERQTLYVLQETTGEARAWNVKVRVRPALTVRQEGEWTWVWALLGVLLGVGVWFLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYI7</accession>
    <name>M5FYI7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_90738</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625509.1">
        <property type="nucleotide sequence ID" value="XM_040776970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYI7"/>
    <dbReference type="STRING" id="1858805.M5FYI7"/>
    <dbReference type="GeneID" id="63692032"/>
    <dbReference type="HOGENOM" id="CLU_073110_0_0_1"/>
    <dbReference type="OMA" id="LDEDEWP"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070139">
        <property type="term" value="F:SUMO-specific endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="82"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="36208" checksum="179D496814AD8C84" modified="2013-05-29" version="1">MSDGDNPPYPETVKQTPEIISAVEPDDMEIDRIGDDDDGSIFRGFSPELGDANTPASRLAAKSSIPFLADMVTDPAKATEEETYIFTFDSLGGSHKAACRHLSKYLIAEAREKKNWTNAREATGETAKVPNQQNFCDCGLFVLHFVQKFMQDPEKFIQTFLKKEKTTKESLDALWGTEDVSEKRNLMKATIQSLADDWNKRKRAEAAEERRAKEASLAPFLEDTFQGTNVSSEEDDGVEIIEIKMGSAVEQGGKKPSAGKGKGRMSMSQESSQDVQILGAPGPVTRRSERRQSDVTPTSSKQTFTGGGIADGVKKRPRPSGAMKRVLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZG5</accession>
    <name>M5FZG5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZG5"/>
    <dbReference type="STRING" id="1858805.M5FZG5"/>
    <dbReference type="GeneID" id="63683599"/>
    <dbReference type="HOGENOM" id="CLU_592051_0_0_1"/>
    <dbReference type="OMA" id="NWNFLAS"/>
    <dbReference type="OrthoDB" id="2559662at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="387" mass="44876" checksum="37BA2A359CE5023C" modified="2013-05-29" version="1">MRVLRRRLVLLLSLPLTLTLLFLLYLHRLQLPPQNAHFRRPSPTPSELLSLRNSSSKYALFHQLRGAGFNNQLQESLLLSWIAKRAGRAYVYRDVIWRPRGYEQVPLEEFVQSLTEQPALHEEAFKRLCDGQKILRAIDGRYPFPERVERVIQDLQGDEQCAYVEGRIMDWPFLDSPAALALYEPFLSYIRDFRWSPWVLEVHARAVGKLGLGEGYIALHIRRGDFSYHCPQIAAQGASFNLWSRLPFLPDTPPHPLSPSTILTHCWPSFGDMLLQIWAAQNQYEQRTGKKLRKVYVLHDAKWDAPWVWILLRRLQFSLSGGPFRLQWVEGGSLPLTWEERDLAVPVDMEIARRAEVFLGNGFSSLTSGVVLFRLADGKEWESNKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZU8</accession>
    <name>M5FZU8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_52131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628936.1">
        <property type="nucleotide sequence ID" value="XM_040775082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZU8"/>
    <dbReference type="GeneID" id="63690144"/>
    <dbReference type="HOGENOM" id="CLU_091791_0_0_1"/>
    <dbReference type="OMA" id="MFARIMD"/>
    <dbReference type="OrthoDB" id="3251205at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17419" checksum="CA1E287D6EDEAE47" modified="2013-05-29" version="1" fragment="single">ALAKTGHFLTVCQHAFICYSPNQINTLSRAKYSIASLAQLLDACSQDIGFGYDIGCTNLITVFQSSIGNKAAASGLRFFVGAFHGYAHNHWCQIHFHPQVLTIAGLKDFETCEWVFSQENCCAHLFRHGSAFHHHMTLDWFYQTWDLDHHAALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0R9</accession>
    <name>M5G0R9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_52279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628607.1">
        <property type="nucleotide sequence ID" value="XM_040775095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0R9"/>
    <dbReference type="STRING" id="1858805.M5G0R9"/>
    <dbReference type="GeneID" id="63690157"/>
    <dbReference type="HOGENOM" id="CLU_111205_0_0_1"/>
    <dbReference type="OMA" id="RIERLWF"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21737" checksum="24EB6EA937C72320" modified="2013-05-29" version="1">MVEHHGANWGSYIWGQLVHNTHIERMWVDVTNSFGWKWALFFLNLEADEGLNHQNNDHLWLLHWLFLQDINNNGTGFQNEWNFHTMSLAEGNQCPADLFLKGCLQHSTRGIQLVTRNDQHYYMNPGSYGSEVDIKLAEAEEDQLEGFIHTHGIANQMPACLSNIDSLPPDCPLSAEHMGQLVNELAPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1U6</accession>
    <name>M5G1U6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626769.1">
        <property type="nucleotide sequence ID" value="XM_040773236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1U6"/>
    <dbReference type="GeneID" id="63688298"/>
    <dbReference type="HOGENOM" id="CLU_2694458_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="9358" checksum="37CD21485E4BB401" modified="2013-05-29" version="1">MTRPVPLRRPYCKYLTVEGSTSCDLGCTISTDPCLSSQERYVNAFNCPLHLMPDSCRIIVRNVQALVGNPCCPQEKTRLARLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1W1</accession>
    <name>M5G1W1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624635.1">
        <property type="nucleotide sequence ID" value="XM_040770779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1W1"/>
    <dbReference type="GeneID" id="63685841"/>
    <dbReference type="HOGENOM" id="CLU_1255954_0_0_1"/>
    <dbReference type="OMA" id="DSEMAHY"/>
    <dbReference type="OrthoDB" id="3336897at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="24791" checksum="9A58C051748EFFE5" modified="2013-05-29" version="1">MSLTPTKTVYEAITYHPNTENREETIKKFTEAIEIQKKAPGFVSIVMEGNKREKPGESVRLIEWETVEAHMEGFRGSPAFAEFKKVREGSTVGDSEMAHYRFFRPLPKIPPVVEWVTIQLKQDTKFEEYFHAWDKALDGVRKAIGCTGIEVGQQVEDPTKALQIQGWETLENHTIDFKQKQADVAVVMEELTAVVNKYVEGGWKGCKGVHVLTTAPGHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1W6</accession>
    <name>M5G1W6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_21935</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629107.1">
        <property type="nucleotide sequence ID" value="XM_040772612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1W6"/>
    <dbReference type="STRING" id="1858805.M5G1W6"/>
    <dbReference type="GeneID" id="63687674"/>
    <dbReference type="HOGENOM" id="CLU_075666_1_3_1"/>
    <dbReference type="OMA" id="RITIEAC"/>
    <dbReference type="OrthoDB" id="10254238at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="39"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU02210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="145" mass="15550" checksum="CB16885B98369E32" modified="2013-05-29" version="1">MAPKSAAEKKPTSTAGKAPAKSTEGAKKTAKTTAPPKAEGEKKKRNKARKETYSSYIYKVLKQVHPDTGISNKAMSILNSFVNDIFERIAGEASKLASYSKKSTISSREIQTAVRLILPGELSKHAISEGTKSVTKFSSSATTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X4</accession>
    <name>M5G1X4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">DJM-731 SS1</strain>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="38004" checksum="9E518FBE139C2D2B" modified="2013-05-29" version="1">MLRKDETVHFRTKGRSRAWTLTQVCAQWRRVAFATPRIWTYLTVTLPSPTPSHEEDLKTTLELSGILPLEAHVRVTTGATMENRQGIIKVLDRLAFRAETFDLRLHSNVTCGFILPAMFYDKLQTLELVGLEVSGSQTWMKSLFNALARCRRLRTLVFHEWHTPKGEPLPTDKIINERRHYANLPSLGYMSLSGKLAPVIATHLICAPRNLAIKDLLGEDEEEDVINLLAPQLGRMRRLHVTQDFCTVETLLQLLQLMPMVEEFGITAQLILSHCRVFAGLPDLIEGLDPERTRDCLDVVIIDSWSARYAWDGFDRVVASVRKMVQHVTVRIV</sequence>
</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
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                <person name="Heitman J."/>
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                <person name="Hori C."/>
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                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Kohler A."/>
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                <person name="Kumar T.K.A."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
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    </feature>
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            <begin position="119"/>
            <end position="134"/>
        </location>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="487" mass="49977" checksum="5D0A0BF60927404C" modified="2013-05-29" version="1">MSTPTPTTDTPTPTPTDSSTPTPTTSSDTPTSSDTPTSTPTSSTPTSTTETTTSTTSTTSTTSTSSSSTTPTSSTTSTTSSTTSSTGITSDTSSTPTTSASSASQPGSVLDLPNSATNTPSATPGPTVPPGGTTYITQTTSNGHVITLTQVLSPTDGSASGSVSFFSNKGAVAGVFVVLGIAVAAFILFMFVYCRKRSRARAFDREVAAAAHAAAASARRKRFDDVDEDKPRTAHYMTPSMRAQQTANTSGTGSDVRASQAPGIAGFGTGQSFAGTAAAAGAAGAVAGAAGAAVGTGEEAHQQPLVDMEDTAQQQQYDYSAYAAQQAQYAPQYYTDASGQVYDQNGQMYAYPSQAHDFQTQQHAAQQGQYEMSDMHGDPHMPSYYNYDSQPIAPQGQAQAYGNYGYDPARLAPDSSWGWGAQPQVVGQGEVTGVAGPQYAQYGHAGEHQSQVGHVAEGYTEGAGGRKDVESVVEDWGGRGGLRVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G240</accession>
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        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
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        <name evidence="3" type="ORF">DACRYDRAFT_99944</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="entry name" value="CUE"/>
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        <property type="entry name" value="UBA-like_sf"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="692" mass="75375" checksum="D1CC24D56F306B0A" modified="2013-05-29" version="1">MTSVSIPLWPTASTKGKIPSSRWESAVNSFVLQLGAALSTPDARSISQNCMPFLTSYLHEEASGRLRQLDSELPSDSAAEFVLRKRAFEVLRRIASVPGTIDPGLLMDAAVVYEGSNHTAMVSLVDEALTVTPALSASLRSEVIPAFVTMLPQPNVTTPALLRSSICLIRLLNCGSSMVDVLSDNQLILAIAKAYNNTPFPSVESEQLVLQAKANLLDSFRTLIYARTSAARHQRTKREGLYELLYLLHDLAPPTSPPDTQHTASSSLVARIQAPILAVYESMYGLSKTLEAMGLVGDATRKYMVQTLKGLRIPGLGQKQVTQPTPPAGLNGSGRNSNAKGKGRSQAPGSTADETPELELKLTQVLDILPDESPDLIRACLRHPPFGGSVEQVVAALLEGNIPAEVRASVGSEERKDAFPLLESRRNVFDDDPLDFSKLRIGKNRDNADGVLRNRAQLDAVKADILRRVQDMSDSEEEDAEAEGRKIVAFEEELDDGMEPSSAVKVTNDGEESEEGDDMEDGEPQSAKKVDVETLLEQTYIRDPKLFDRDAATRRTKQRADLRAQTGWSDEQLEGWRIMLERNQPRKDKILQKHEFSGNRPLVPEDEGQPSSSHASDREGQSSHQVRGRGGRGGRGQGAHRGGGGEGRGGSNSARDRAWKDKNKARQGNHDRKRGHDKKLARAAGPPASDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2F9</accession>
    <name>M5G2F9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_79206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629294.1">
        <property type="nucleotide sequence ID" value="XM_040776384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2F9"/>
    <dbReference type="STRING" id="1858805.M5G2F9"/>
    <dbReference type="ESTHER" id="dacsp-m5g2f9">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63691446"/>
    <dbReference type="HOGENOM" id="CLU_006586_15_2_1"/>
    <dbReference type="OMA" id="DMYTYAY"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140964" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="25"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="363"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="520" mass="54398" checksum="3E39A6D1EF010597" modified="2013-05-29" version="1">MPSLLQLSLLALGATAALLPRDDGTLITLSQGSVQGTLVTPIVRQWLGIPYAAPPTGSGRFQPPQAAPALSGTLDATSFGNSCPAVFPIEYLELTGLLQQQESVPYDEDCLNLNIWAPATSRPQGTAVMIWVYGGGDMFGTSNTPFYNGIEFVQANDDIIIVSFNYRANIFGFPNAPQQLVNVGLLDMDAAIQWVSANIAAFGGDPERITIFGQSAGALAVDAYAYSHPSDTIVKGIIAESGTAQLTSVLSAGSAVPTAANSSWNTVATAVSCGGANDAAQLSCMQAVPWQTLLSAVTASAKSFTPYPDGQTIFSDVSSRSSKGQFLKVPLLMGTTANEGDIFVLAYEESSFGGSIPVLGTVLSDAFTELVFTCPASKSTNDRAAHGVSTWRYRYEGVYPDLTDENPALRAYHASEIGLVFGTYNVSTLFPPTAGEIALSAYMQSAWASFARSPSTGPGWAKYSTALLTSTIAELGNNKNPGGATLAPPLEFDVGCGVVNVLEPYVLQLLSIFGVGGGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2K6</accession>
    <name>M5G2K6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_116133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629344.1">
        <property type="nucleotide sequence ID" value="XM_040770145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2K6"/>
    <dbReference type="STRING" id="1858805.M5G2K6"/>
    <dbReference type="GeneID" id="63685207"/>
    <dbReference type="HOGENOM" id="CLU_010458_0_0_1"/>
    <dbReference type="OMA" id="VYEWQSE"/>
    <dbReference type="OrthoDB" id="3142434at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000602">
        <property type="entry name" value="Periodic tryptophan protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000938">
        <property type="entry name" value="Probable periodic tryptophan protein PWP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="471"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="7">
        <location>
            <begin position="747"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="650"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="883" mass="98181" checksum="D36E2D05FA4E18CA" modified="2013-05-29" version="1">MKANYEFSNLCGTVYRQGNILFTPDGNSILSPVGNRVSVFDLVKNTSRTFSFENRKNISVLALSPNSRLLLSIDSDGRALLVNYRRGTVLHHFNFRVPVVDAQFSPDGAYISVTHGSHVQLWRTPNHLLREFAPFELHREYTGHHDAVLSITWSADSKYFLTTGRDMTARLYTVDPVEGFRPRTFAGHRDPVIQAFFSADNKTIYTVSDHGAIFTWRAKADENGKDDDAMSEDGTSLTLAEPILAHVRWGIAEKHFHNMDHHTLIVSAAFHSPSDLLVLGLSSGVFGLWEMPSFTPLHMLNVSQERISSLAINASGEWLAFGAAKLGQLLVWEWQSESYVLKQQGHYFNMNTLSYSHDGQHVATGGEDGKVKVWNASSGFCFVTFSEHTSSVSSVEFARQGQVLFSASLDGTVRAFDLVRYRNFRVFTSPTPVQFSSLAVDPSGEVVAAGSQDNFEIYMWSVQTGKLLDVFTGHEGPVATLAFSPTGNQLASGSWDGSVRLWDLYGRSRAVEPLQMGANVLAVAYRPDGKELAVATLDGQLTFFHVEDGKQVGLIEGRKDISGGRKTDDRTTAANNSGSKHFNSLAYTADGQNVLAGGNSKYVCLYDVRERVLLAKFQISQNLSLDGTEEFLDSRKVTEAGNIDGIDRQGEASDLEDRLNPRLPGAQRGDMGKRRYRQEARTMCIRFSPTGRSWAAASTEGLLIYSTDESIAFDPFDLDIDLTPQSLLEVLAQHEYLKALVMAFRLNEKPLIQRVYESIPPSDVRLLARQLPMVYVPAMLRFVADHIERSPHMEFDLVWVNALLAAHGRELRDHSNEYASVFRAMHKGISDFERMIGKLCDDNMFSLQYIIDQSHAKNTGHPNGKVPSLDMEIEVASEVSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2M7</accession>
    <name>M5G2M7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_118801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624915.1">
        <property type="nucleotide sequence ID" value="XM_040770660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2M7"/>
    <dbReference type="STRING" id="1858805.M5G2M7"/>
    <dbReference type="GeneID" id="63685722"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OMA" id="FYLPFRA"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="392" mass="44159" checksum="7322C58305E209A8" modified="2013-05-29" version="1">MLMNLDLICFSLLVLLTVIGYVIRQRFIHPLSKYPGPFLASLTNLWSTYLAYRGDWHIVLDRLHKRQGSIIRIAPNEVSISDPSAMKMIYSVTGGFSKSDFYDVFRIPTDPPSLFTDRDEARHTDRRRLVGSVYTMNNLLKLEPHVQIIISRFVKQLDKLFGSTSDVADMSMWFYRMAYDVTGQLSVGRSFGAIEEGDRFGFLVELPFSRLLASQLNIHQSLFADRNAHGGILGRAPAWARPIIGKFFNTTNIQVYKDITDFMQSSMNVHLASPENHADMMSMMLELRDAKGQDLLTTDQVQRDCKAKEIDEASLELEADQPFSAAMARSASSVLSVKKLTYIETEKLPYLAACIQEALRIHSGVGFPLPRVVPDDGAVIAGEVFPAGNRWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2T9</accession>
    <name>M5G2T9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629434.1">
        <property type="nucleotide sequence ID" value="XM_040777610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2T9"/>
    <dbReference type="STRING" id="1858805.M5G2T9"/>
    <dbReference type="GeneID" id="63692672"/>
    <dbReference type="HOGENOM" id="CLU_010913_4_0_1"/>
    <dbReference type="OMA" id="NHNSAHG"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="104"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="259"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="570" mass="62241" checksum="6FDB80FFCA2F75CC" modified="2013-05-29" version="1">MGNLQSSLHSLNSAHSSTLCACLLCNLTARSIHWTVSSGSEKAIDDPSYDTLPVLSGHASVSSTATQVAYTQFLRTYPEYRDTAALDTLRKQDFTRLGNTKETYVDYMGGHLYPESLVRAHAEFLAQHVMGNTHSVSNSSAISAAHAAEARREVLAFFDAPPGYAVIFTPNATGALKLIGESYPFGQGSTYLLPGDCHNSVNGIRQFASSSGADVAYLCCQAHGGIDLEEAQRETLSGTDIISDSSKRMLSERAPQKGNPSLFVITGMSNISNTKTPLSIAEQAGARGWHTLVDAAALAPTAHISLRENPAVDAMVVSFYKMFGYPTGIGALIAKESFLRQLKRPWFAGGTVDVVQVPGTLVTMSLELYEQFEDGTINYLGLPAITNGLRYLAPKLPLIQTRVGPLFAWLSTELQKLKHETTGAPVVKILSRQPSSVPEGKDRWQVMNKEIGYTLSMIFFDAEGNMFPNSFIEHAAAQKRISLRTGCVCNPGGAAAILGIEHNMALLKLGVTYKDFEYWVGRELGVVRVSLGMVTDFEDVWRVWAFARDMGISERREVLWDAWRESKPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2X4</accession>
    <name>M5G2X4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_99454</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="2"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629943.1">
        <property type="nucleotide sequence ID" value="XM_040777590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2X4"/>
    <dbReference type="STRING" id="1858805.M5G2X4"/>
    <dbReference type="GeneID" id="63692652"/>
    <dbReference type="HOGENOM" id="CLU_1396265_0_0_1"/>
    <dbReference type="OrthoDB" id="3356616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049482">
        <property type="entry name" value="ANM3-like_C2H2_Zf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21137">
        <property type="entry name" value="ANM3_C2H2_Zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase 3-like C2H2 zinc finger" evidence="5">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="21966" checksum="9EA0E593431F12C8" modified="2013-05-29" version="1">MSLFGPNKLFGSLREALSDAKGNYGVDSGEICDRLELDFYDRMRLVNFLRKERPPPDIVNTMTGHEPFFKDDVFLIPVIPDDPLLQAHQETPWSDDEDSAPGLAALASRSSQPVDLSRELRRANRTIRSLQQQLGQAKQDLVDYKGIVNKALGVNDVKQWVEMKAGGDGDAVLHREDPQYFDAYEDIADDDNLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Y6</accession>
    <name>M5G2Y6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627084.1">
        <property type="nucleotide sequence ID" value="XM_040773139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Y6"/>
    <dbReference type="GeneID" id="63688201"/>
    <dbReference type="HOGENOM" id="CLU_1255953_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="23703" checksum="40F26A05861E3A64" modified="2013-05-29" version="1">MQRRTTLASGSKPVQVQSWWTSTIPFSALGCVPPPLQARPWPVPAMQRRVTRYSRSISSSSPTNVNVNVRPISAPAIASSTARAMGMTCLNSGRQRSRGSNTNKQGQQPEGGCSLGMSEREDGLVFASTREWLSRCYATGWDEPVAQCDSGPVSAVIHHVYLCPMLLGGHPARVGPAIHPSNHASLPRHPSVSGNTSTAHARNSMQLAPTSPRQRTNLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Z4</accession>
    <name>M5G2Z4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_111113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625030.1">
        <property type="nucleotide sequence ID" value="XM_040769176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Z4"/>
    <dbReference type="GeneID" id="63684238"/>
    <dbReference type="HOGENOM" id="CLU_395881_0_0_1"/>
    <dbReference type="OrthoDB" id="10493021at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="696" mass="76105" checksum="226917FD8C507127" modified="2013-05-29" version="1">MYIPYSSRHARQQPAQAVPINVDGHPSVRPSSLLIRASSLVQSYIRMTTRLVCAALGLGLALVLAVSGLFALVLFQCRARKKGRRQRAMSGESFACPGETAGRPRPAGWRAQPRTAVNAPLLEQDSISPTFTAPPPAYTESVSGSLTTATSLTLPRILTDEIGLRPRAHTLESRSSIAPTSSVAPSRSFLQLLSAAGLRNSVQEDTQYAHISTEEGRNTNRRYHKCFTKGTAELEVVSSYASEDEEGQSSPYDPADYPARPPHSRHSRNVSRQSSDLAYLQEDNNLIDNRPTSRASCARYSRFSQAHSRTKDSITSLESDLLTRLTPEPLTPITPCMVEPGGLQVGWSFPVARDRDAAFYQRRYHASLSETSPIKLELPPKPSRERSTTHPPQGPILHHLVNPIYNPAAARSKKGHRRSKSSGSVSSTSSGQPLAMGLGMVGLGLTLGATLHNGTGLRRLSLVPEEENPSIGEIKRPESVYVPTATRTQTGMHRRSQSMPVERSSLTLIPPNPILPHHRRSPSLVSADTLTSSSNRSSSPIFLSPLLSTPSTTGPETPVFAFPPEAPATAAGRERSTTLSSVDGDHLTIKIYYSSHGHVDPSRNSYFDSSTETVKFRLPRTAVFGELCIKVWEKLGLPVNLLMYDDMTVDEDSDLEGEGCAKRKMVGAEEWRDVCERAQSRVYFWAKDAEVNIVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G392</accession>
    <name>M5G392_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_58119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625115.1">
        <property type="nucleotide sequence ID" value="XM_040775484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G392"/>
    <dbReference type="STRING" id="1858805.M5G392"/>
    <dbReference type="GeneID" id="63690546"/>
    <dbReference type="HOGENOM" id="CLU_093552_2_0_1"/>
    <dbReference type="OMA" id="FCINCEK"/>
    <dbReference type="OrthoDB" id="5422613at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18745" checksum="2E57606AAC22CD88" modified="2013-05-29" version="1">MPTQTRDAVDTAPAELLTDEVKSQLQEAIKTVSEKQLREFVAELARKEPAAERELVKMLLVPRSKRKRADEVQSRWMACANCRVEYDVGEDRKAGECQYHPGELEPDYEAFVDDDYDETTIESEELMQEFPENYNWTCCGEDGTVEGCIAGKHVHGGESKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3P0</accession>
    <name>M5G3P0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase F(0) complex subunit e, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_51184</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase e subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629729.1">
        <property type="nucleotide sequence ID" value="XM_040775030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3P0"/>
    <dbReference type="STRING" id="1858805.M5G3P0"/>
    <dbReference type="GeneID" id="63690092"/>
    <dbReference type="HOGENOM" id="CLU_159435_2_0_1"/>
    <dbReference type="OMA" id="FYGLYHQ"/>
    <dbReference type="OrthoDB" id="2125027at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008386">
        <property type="entry name" value="ATP_synth_F0_esu_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05680">
        <property type="entry name" value="ATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 11" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="9563" checksum="2C68F281E9B56B59" modified="2013-05-29" version="1" fragment="single">VVRYSALLGGIFYGIVHRRTLQGEENAKKEAHDHQRRDQLIKEAREAWKKKQVTPTSGGELITDPEDPKFNLEDAMEQWSKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3R9</accession>
    <name>M5G3R9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630213.1">
        <property type="nucleotide sequence ID" value="XM_040768276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3R9"/>
    <dbReference type="GeneID" id="63683338"/>
    <dbReference type="HOGENOM" id="CLU_821410_0_0_1"/>
    <dbReference type="OrthoDB" id="10622559at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="338" mass="36857" checksum="46110BF14CA1B7A2" modified="2013-05-29" version="1">MTRFNTGYSVLYPCWRGTLPDPEEDTQVADYATYMDLYAYEEQKTLFPPRQKQFDPQAQDSVIYAPDKAVDLTAMWARLEREEELAEPCYFSGTADSSFSLSNEDSLEYLFSESGDDAMDEDQDFLLHDLLNDTEYMAACQNLSSAPPLSSAGDLSASSIQDMMVVEVLLDSDYIGDQTMVDSDPDGLSPSGSSGSSGTLLSALASPFVPSFLKSAGGEKHGAQFLNQVNYALTSGEYEDFPHGFSLSCSTDYSALPTPEEASFPKFLTHEYDGIHDSATSLFKSLPQSSPPRIPGMKSARIKSMGVSLSDVPVLSSPEKSHLGARRSARKISTGPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Y6</accession>
    <name>M5G3Y6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRAL/TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631860.1">
        <property type="nucleotide sequence ID" value="XM_040771975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Y6"/>
    <dbReference type="STRING" id="1858805.M5G3Y6"/>
    <dbReference type="GeneID" id="63687037"/>
    <dbReference type="HOGENOM" id="CLU_014001_1_1_1"/>
    <dbReference type="OMA" id="DIHARPC"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
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        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="99"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="39680" checksum="E55538D2D9690A1E" modified="2013-05-29" version="1">MVVIHKPFLPPPRPDAVPTLVSEPDQEKYDTLLNHFSDPAFQLQGEKETEKTALTEYEKYWLSKECFLRYLRATKGDVAAAIKRLESTLAWRRSYGFYRPDFAEHVEPEGVTGKCLLLGYDVAGRPGVYLIPSNQNTEASERQLEFTFFVIECAIDLMGPGTENIALLINFGDKGKHPPMWIARKMLGILQGHYPERLGKSFVINIPWYVDMFLKMIWPFVDPVTKGKVHFNPNVIKENLMTPDMLLSEWNGEIQFTYEHSQFWPELLRIVKEYRGANMGRWRTLGAKVGISEWDYKNGSSVLRTFEETEKGQTIEATGGYEDVEREANEELQREMGPEGLVEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G476</accession>
    <name>M5G476_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_14144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631960.1">
        <property type="nucleotide sequence ID" value="XM_040771017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G476"/>
    <dbReference type="GeneID" id="63686079"/>
    <dbReference type="HOGENOM" id="CLU_1089989_0_0_1"/>
    <dbReference type="OrthoDB" id="10612947at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="255" mass="28912" checksum="3A0A9ED259D06D0D" modified="2013-05-29" version="1">MDQAKHMANIKRMNKDLLDDWNHAVDRARATGSAIPQKPILPCTKVKEHVLPLDDCKVLLDDNPIVAYAKAYQEWCEPQKALPRILSMPSAMAKNKGKASWFGRVKSSDSFALSPSPLAITMTPRTTDSLSLPVNIIDVDKMRCLVHTSAHGLVIMPGPMNSFKCLVFLCPSDDAGFAMMHELPYKTKQTMIDMAKDLGRACYDEIEWELQILYNFDHPNTWTEKMENKISSIYWKAIFLVMCKDQLMDRANGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V5</accession>
    <name>M5G4V5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nucleic acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_115462</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770007.1"/>
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    <dbReference type="OMA" id="QVCRTVC"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10289">
        <property type="entry name" value="GST_C_AaRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000047">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="TRNA-binding" evidence="9">
        <location>
            <begin position="222"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="395" mass="42268" checksum="4F0A97289FCD022C" modified="2013-05-29" version="1">MSAQAMLGNLPHGLREVVEKASEGDNYFGRTEKDKGEVVEWTTKVSQGAVSSGDGLKTLESTLTSRTFLVGNELTAADVAVYASLYPILSKRTPQEYYSQPSITRYFDHLQHLSSVAAASKAANLSPVTFDLDHMPPLERAAAPVKEKKPKAPAASEQPPVEVAPQAPAAQAKESQPAEEGEKTGKADKKDKKKKEAKEGAAAAGGKGGKAPAAAPEDSEPAPSMIDLRVGHILSVKRHPDADSLYVEQIDVGEPEPRTVCSGLVHYIPIEQVENRDVIVVCNLKPVTMRGVKSFAMLLCASSKDGKDAGIEFVNPPPGSKPGDRIYFEGDKYETAQPLPQLNPKKKIFETIQPGFTTLDTLEAAWVDPVTGSVHKIRTKEGVCKAATFVGASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V8</accession>
    <name>M5G4V8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_22748</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627789.1">
        <property type="nucleotide sequence ID" value="XM_040772937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V8"/>
    <dbReference type="GeneID" id="63687999"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="WVETKNT"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="37"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="58676" checksum="DA7663ED54E1A1B5" modified="2013-05-29" version="1">MAPGAVSNKEPTALAIAELLDPRPWYKNGRLLALNAWIFLLLITSYTNGYDGSMMNGLQILDQWKGAMGNPAGGKLGLLNAIQNIGALCATPIAPYVTDGIGRKLAIIWGASLMIIGTAVQSAAQSVGMFTGARFLIGFGLTFAANAAPLLVSELAYPPHRAPLVSTYNSLWYSGSIVAAWTTFGTFRISTEWAWRIPSILQGLPSVLQVCLIWFCPESPRWLVSRGKHEKALNILAYYHGRGNEQDPLVQFEYNEIKEAIALDKEIAKNVGWLTLFSTPGNRRRMRIIIAIAFFSQWSGNGLVSYYLNLVFSAIGITSQTDQTLINGILQIFNLIVALIASFLCDRAGRRVLFLTSNVGMLLFYVMQTICFAQNSITGSQAAGHGVIAFIFLFYLAYDIAYTPLIVSYTVEILPYALRAKGFTIFNFTISLALIFNQYANPIAMDAIGWKYYVVYDCVLAFEIVFMFFYCVETKNRTLEETAALFDGEDKVDTIAARAGTQAGVDAALGRHPADNKQDEEYDEKHEHEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G530</accession>
    <name>M5G530_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630224.1">
        <property type="nucleotide sequence ID" value="XM_040770020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G530"/>
    <dbReference type="GeneID" id="63685082"/>
    <dbReference type="HOGENOM" id="CLU_023533_0_0_1"/>
    <dbReference type="OMA" id="IPSWTQP"/>
    <dbReference type="OrthoDB" id="3363891at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="855" mass="92224" checksum="B79D7B2C40EE4ABE" modified="2013-05-29" version="1">MAVATAGSNLLINPYDEMVVPALRKRLEAESRLLTSRLSGSFDAYSIPEPHNTPSTSNRGVEAASGIPASKSRARVASPDPYNKPSSIPRPSLQMSAQYAQSTRDLLLGANGSSTTSKQDRVTRSDRIPQQAVMRDREQDREKELGKGKGKEQENRAPGQRARSRTQSTPYACNELVASAAAATAAVAGAPSVLPTPASSRANSPQNQPNGSTSAMNPNGQNLTASALSSRPSGIPVPRSTPARPSAKTPRSRSRNATTPVTFPTPAEDGHARDDLDLQHLTPEPRMRYPPSPEPSPELSYIRNVQAPFPLSGSVMGGGASDSDAGRSSFERDMRASRAARRRNDRSGKDDRGGLGEIELNYRGDTRRNGGRGEVYKGHTEEQLEIATFGHDLSAERKALNTGPQRRRGELDYLGVPDDGTVRIKGSAPSPNSKQHMAWGELALAAGYGDGYESGEMELHDESVIRERPLTWMVEGEASVTDLVLQSLRNEGGRESVELLSHAEEAEEHWELAHEQLEPEGLAYEQPRQPAQPEELPIRNGAGTAAKTQPMKVHAKGRLQQVGLNKSAPSGQRAPESSGIASKKDAKTNGNANPAGTSAQTRQRVASKPNTPAARQRVASKPSKVSGPAVSAKANAQPRSKSQPINPQKYEQRDSNASMSLADAIPDIPKRGIERGRNWDEVVLPTVAKQLGLDKHDDDLPEPEPEEVIYPPAPGTFDYDHSKYRAPTPSDTVAHTPRPLSPQSADGHLAPPEKISHRVSREITPPKPPVESPPVQVPPRISSPAPFASYSPLSERTPVQAADVKLQKSSTAIERSKDIRQSKPPKIKISPPAEFAMEVDRDEEKHTSGCKCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5C1</accession>
    <name>M5G5C1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040769946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5C1"/>
    <dbReference type="GeneID" id="63685008"/>
    <dbReference type="HOGENOM" id="CLU_826446_0_0_1"/>
    <dbReference type="OrthoDB" id="10359761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="336" mass="35455" checksum="39EEB2B6F20F3069" modified="2013-05-29" version="1">MQMRPQPSWASFGSDSTPDEEADDHSSTGDSFDSDLMDRHIRTASTEFTGFIPSTGDRNGPLPATGTAYMPPKPKSVKGAETFPEPAAPKHLLPEMKAQAPRPHGSSRRRQANCPVAAPPGVDPVEQARIDFIRKALPPSAPPTRRSSIPGKEQTPPTRTVGKRDTLRADFHLPPRASFESRASSRAESSCPSLSKSQSSSSASSLSPSSAGSSANDLSSSKPTAPMQGSAPFKLSHASVKEGRRVSQPFAFLSRSSPPVAGAKKPSGPPTIQPKGVPPTHGPSKSASSTSLRARFNSFERGAVTPVPPVDAASLVGKNNVMSKGLGRFFKRSNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5P3</accession>
    <name>M5G5P3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gpi1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_74837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632475.1">
        <property type="nucleotide sequence ID" value="XM_040776090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5P3"/>
    <dbReference type="STRING" id="1858805.M5G5P3"/>
    <dbReference type="GeneID" id="63691152"/>
    <dbReference type="HOGENOM" id="CLU_065637_0_0_1"/>
    <dbReference type="OMA" id="WNIFRGK"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329:SF3">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="43156" checksum="3D6F81966B1A1083" modified="2013-05-29" version="1">MRLPSLFVHKPLLKDISATIQQLDTRLEQATFLPNQFDVVHRLPRTDMAYSAAQYINFYNCIWLILNDIIVGVAFGAFLNENSQYLGHLLWFYTKVYAVDLIRDTLFWLDDWPVGLKLNTELSRFICLSFIGLTGAFEVCLNILGPYFPIVVYVIGSSGTMGLTMTLSLLSDLLSLLSLPLYFSYMTVTTVFSAMLSTSYSLFNIFRGKRKNILRNRVDSMEYDLDQVLLGTILFTLVAFLFPTVLAYYAFFAAVRIAIILMHASLETSLAFMNHFPLFVLMLRVKDPARLPGGIQFEISAPKGDVPSALILKNTPIAFGQIFFQHFLLWSRLSAHYHPIRLLKCLVSGVVISPIPRYSIRYSMIPHQASLPARDKSKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G602</accession>
    <name>M5G602_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_48315</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631043.1">
        <property type="nucleotide sequence ID" value="XM_040774822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G602"/>
    <dbReference type="STRING" id="1858805.M5G602"/>
    <dbReference type="GeneID" id="63689884"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="SEQMNAH"/>
    <dbReference type="OrthoDB" id="10250725at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF10">
        <property type="entry name" value="NIMA-RELATED KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="35299" checksum="A22E05FF43C300F2" modified="2013-05-29" version="1">MSARPSATPTPSSTQSSSSALGSPAILTDYEPLEIIGNGSFGIIRKVRRKTDGVLLARKELNFERMTERDRKQIVAEVNILKELQHDNIVRYHDRFVDREHGILYILMEYCGGGDLSGIIKQSRKLKQPVPEDTIWAYLTQLLYALHYCHHPGAPLPGAGGAQGPEAGQIDCREGKQVILHRDLKPENVFLDANGSIKLGDFGLSKAISSSTFANTYVGTPYYMSPELINDSPYDIKSDIWALGCLLYELCAWNPPFHAAQTHQELAVHIRSGRIPPLPKQYSSTLVGVIKSMLSQAVRSKRHGGMPSLCYPFIAARTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G678</accession>
    <name>M5G678_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exocyst complex component Sec6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_77423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630599.1">
        <property type="nucleotide sequence ID" value="XM_040776270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G678"/>
    <dbReference type="STRING" id="1858805.M5G678"/>
    <dbReference type="GeneID" id="63691332"/>
    <dbReference type="HOGENOM" id="CLU_011776_2_0_1"/>
    <dbReference type="OMA" id="MNIGPKT"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.50:FF:000006">
        <property type="entry name" value="Exocyst complex component sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="757" mass="85678" checksum="429FC9B009DF31F0" modified="2013-05-29" version="1">MSLPTPQPISAAHAIGELLKSPDDLLKIAALRKRLEKEKASINVKLKSGVKDQLEATREGLRKLMGTRNNVQSVKDDMANVHFLCQDPGARAGEFEQISWMSVIHRNFALTEEMVSNLSEMYTKLATLESQLSAARDDPLGPSPHLLPMHYQITQLEAFRNQTLHQAKRANSDARKTLARYFERLNGTIDAFDDYLMLLARSVLGLVRAGQPAVVVKLIKIAEVEGREDEKALAIRLVKKMAKIDAAAKFKSMQANARVIKNYRSKIFTQISASIQESFTAAYMQDRDAPGAFLDNLQWMYQDLVRIQDDVVPLFPADYEIFAYYVKAYHKSLNSVLVEILETGPEASVLLQLHAWVKDYKTNMKELSIPQELITPPLLDGKEQGLIDDYLKLIIGKMDEWSNNLMRTEIRDFSTREQPPEVDSDGLYGMQGAVIMFQMVNQQADLAADSGQGSVLASVVGESSRVMRRTQEQWVKLVDLEFKKQTDKPDEVPPGLGEYIIALANDQIKCADFAEALSARLEPLVSEKYKVIISDRLNEAMDGYLDVAKKSTQMIIDLIMHDLRPATKALFTTTWYGGVMTQIVETMRDYMNDYQPYLNPFILDLLVDDLLDTFLMTYLTALRRCSKLQMPMAADRIRDDISEVFSLFSVFKQPKELETNFEIIELILAMLTASKKLVFLDFWNFAKKHGPNLGFVEAIMRARDDLTRSDVSEVMESIKRKVKEEKLGEPAEPTIMNRITGQSAFANIQNVVANLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6A5</accession>
    <name>M5G6A5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6A5"/>
    <dbReference type="STRING" id="1858805.M5G6A5"/>
    <dbReference type="GeneID" id="63687159"/>
    <dbReference type="HOGENOM" id="CLU_1224731_0_0_1"/>
    <dbReference type="OMA" id="CNEREMT"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:transcription regulator complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="24723" checksum="3E49B5F612EAA337" modified="2013-05-29" version="1">MSFVVNSQYGRVSLLDGLTPDDLGQSVTGSAPCNEREMTSCTLSSPSARYKCLVCCKIFSSAGHLNRHSTMHTGVKRFECPFPGCGKQCSRSDNLVQHFRLHLSESLRAEINSIVRGLMEDMRAKETQSHSAKHDDGSLRQQQPMLTSHCESPVTVRGRAKPTALQTGHRSASLSSTSSSSPGPASPLPFPWEPPGRMSATQSLSWDELGSNRWPSKIKISYARAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G772</accession>
    <name>M5G772_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Galactose oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_47671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631468.1">
        <property type="nucleotide sequence ID" value="XM_040774774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G772"/>
    <dbReference type="STRING" id="1858805.M5G772"/>
    <dbReference type="GeneID" id="63689836"/>
    <dbReference type="HOGENOM" id="CLU_019536_0_0_1"/>
    <dbReference type="OMA" id="IAIDCHM"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
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        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="46865" checksum="935E35E042EAFA2A" modified="2013-05-29" version="1">MNTPFPISKPKTRGRSHTVTSAHPSSSSPTSSSSPSTSPDTSTASPPITSVLRQTSGGRRRACPPSLMYWSRAPIIPPYPTHAHAHTPKGVRSASCTVMDTAIWFFGGYDSKETVEDVWVLDTETREWERVEMRGEGPGPLRAHTAVGDERYIFVFGGGSGDEFSDELWALDTFEQTWHLLPCSAPSPVPRRAHNSFIYDEHLYVYGGGSGHDALSDLWRIDVSWAALARSKDEPLVWEELQTSGSAPSDMPVPGEEGSPEENTPRARGYTSATLVGNVLVVLGGQSGRDGDGEGPWGDCWVLNLDDLHWEEKHLNPPIPLASHTATLVGMYLFIFGGNDGSRYCNDLRLLNLITMQWETPKIRGHPPPERAQHQAVLVDARLWIFGGFDGRRYFEEPYVLDLAASSWLMGVTEFGVGEEEEGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7K4</accession>
    <name>M5G7K4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631603.1">
        <property type="nucleotide sequence ID" value="XM_040771902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7K4"/>
    <dbReference type="STRING" id="1858805.M5G7K4"/>
    <dbReference type="GeneID" id="63686964"/>
    <dbReference type="HOGENOM" id="CLU_022049_2_1_1"/>
    <dbReference type="OMA" id="VLEWLFK"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="466" mass="51257" checksum="C9BE7CCFBC33D89B" modified="2013-05-29" version="1">MVSPLVAAARLQTRANAFRLASRSSRFYSTKPQSLKERLAELIPKEKENVKAIRTEYGAKALGQVTVDQLYGGMRGLPALIWDGSVLDANEGIRFRGKTIPECQDLLPKADGGAEPLPEALFWLLVTGEVPTAEQTKAISAEWAARAELPKFVEELIDRCPPTLHPMSQFSVAVTALNHDSAFAKAYQNGIPKAEYWGPIYEDCMDLIAKLPAIAGRIYRNVYGDGKLPAIDATKDYAWNLSHLLGFSDKEAFVELMRLYIVIHSDHEGGNVSAHTGKLVGSALSDPFLSYAAALDGLAGPLHGLANQEVLLWVMKMRSKVGENPSDQDIKDYIWSTLKSGQVVPGYGHAVLRKTDPRYMAQRAFALKHLPEDPLFKLVGQIYNIAPGILLEAGKAKNPWPNVDAHSGILLTYYGLDQMQFYTVLFGVSRAFGVAAQLIWDRALGAPLERPKSYSSEAIKKMFVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7R8</accession>
    <name>M5G7R8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626720.1">
        <property type="nucleotide sequence ID" value="XM_040768846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7R8"/>
    <dbReference type="GeneID" id="63683908"/>
    <dbReference type="HOGENOM" id="CLU_1184972_0_0_1"/>
    <dbReference type="OMA" id="TITSARC"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067521" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="26682" checksum="7512377D09C98BFF" modified="2013-05-29" version="1">MEWLIYAYAFLFTSLTQVKAIARAIFNRTIPAIMFEPAQPIVAQTNYVQPYRTFTPPVKENKDTYGKTLTHFQFPWPIEINGIERVVLSAKGDLQRVLSAYFGSPISVSPIFQTPASSIPVSSEASPSTPITQHRVVHLLCASKLVVVATSTVHLYTPRAASLLLDEKYAIGQCYRVMGQNPEFELDKVWLDNAATGEERVTRRYRLSTEEMMCEIEEVFVDRKMFREESWLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7S2</accession>
    <name>M5G7S2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628829.1">
        <property type="nucleotide sequence ID" value="XM_040768514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7S2"/>
    <dbReference type="STRING" id="1858805.M5G7S2"/>
    <dbReference type="GeneID" id="63683576"/>
    <dbReference type="HOGENOM" id="CLU_2291597_0_0_1"/>
    <dbReference type="OrthoDB" id="3247681at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11003" checksum="160C1101069D84EF" modified="2013-05-29" version="1">MHTVTMFHELAAAFASQTGGHACGFIVCGDIKDTTKPTFFGDNLCKQFFEEVMKIGLAAFAQNLEAFCMSGGAKGLAESTHKHMLALKAYICAMLNERLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7U8</accession>
    <name>M5G7U8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_63860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631099.1">
        <property type="nucleotide sequence ID" value="XM_040775742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7U8"/>
    <dbReference type="STRING" id="1858805.M5G7U8"/>
    <dbReference type="GeneID" id="63690804"/>
    <dbReference type="HOGENOM" id="CLU_126331_2_1_1"/>
    <dbReference type="OMA" id="HQIGDYW"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13396" checksum="FD024CEB555A96D1" modified="2013-05-29" version="1">MPFYEIVCIAVHYPQYQHIHGLIKASMKAVFDAGGVVRQLTSDGTKILPQRIRSHQAWHSYGDYWTMRFDASPKLMKTVTSSLTQDPRVIKWTVIKLGTKLEDILEPPSKTVRWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U9</accession>
    <name>M5G8U9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_61457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633530.1">
        <property type="nucleotide sequence ID" value="XM_040775671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U9"/>
    <dbReference type="STRING" id="1858805.M5G8U9"/>
    <dbReference type="GeneID" id="63690733"/>
    <dbReference type="HOGENOM" id="CLU_066296_2_0_1"/>
    <dbReference type="OMA" id="QFNEGGI"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="20805" checksum="9A5D1C60DB36CE74" modified="2013-05-29" version="1">MSLNWAMLDPANSQPIPLPEEEMILHLSGAEFTLLVPDAPPPTSGAQSAGGAGGNPKRSVATGTVWVSDHRVIFVPIQAKDVPYHSLSLPHNSILSTSFQQPIFGSNHVILSIAPTTGGGLTQGTKAEVRFKDRGVFEFVKVLEAARERSINRERERGEEGLPMYEAPPPPVGASGTAPTGSSHAVHEDAPPGYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9M6</accession>
    <name>M5G9M6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication protein A subunit RPA32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_63285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631869.1">
        <property type="nucleotide sequence ID" value="XM_040775729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9M6"/>
    <dbReference type="STRING" id="1858805.M5G9M6"/>
    <dbReference type="GeneID" id="63690791"/>
    <dbReference type="HOGENOM" id="CLU_051033_0_1_1"/>
    <dbReference type="OMA" id="TFHFIDC"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="70"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="8">
        <location>
            <begin position="162"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="281" mass="29758" checksum="509DF35DDA8D9718" modified="2013-05-29" version="1">MSSPYYGNAGGGGGGGFSRSPYGSQESPSGNTRKAGTHSLRPVTVRQVVQSDHAFGDAEWQIDGSDAPSVTFVAQVRGKAQQATNTAFSLEDGTGQIDARLWSDSQDPDTAAGSEIENDVWVRVQGTIKEFNKKKHVAAQRVRPITDMQEVYYHYCEALSVHLELTRGQVKGGGGALTSGAANVHAQVNGPTNVSSDYTMGGGGGGTANNYAHMPALDRAIMQFIESSANSDGCHLTAISRAVARPGVTAEQISLALERLSDDGHVYNTHDDNHFQSVNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9P4</accession>
    <name>M5G9P4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA topoisomerase</fullName>
            <ecNumber evidence="3 11">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_92803</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 11"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632423.1">
        <property type="nucleotide sequence ID" value="XM_040777108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9P4"/>
    <dbReference type="STRING" id="1858805.M5G9P4"/>
    <dbReference type="GeneID" id="63692170"/>
    <dbReference type="HOGENOM" id="CLU_002929_1_1_1"/>
    <dbReference type="OMA" id="MELAMGD"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000005">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 11 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="13">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="15">
        <location>
            <begin position="162"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="14">
        <location>
            <begin position="699"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="14">
        <location>
            <begin position="767"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="605"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="811"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="655"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="829"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="857"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU05529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="866" mass="97054" checksum="0CC54B55B00D6DAB" modified="2013-05-29" version="1">MEILCVAEKPSIARAISQILSGGQSTTRDSPNRFTKNYDFYYDELRAEITVTSVAGHLMESDFSDDYRRWESCDPADLFDAPIITAVRKDGGPIARNLEIEARGKNMLMIWTDCDREGEHIGSEVASVCRKTNARIEVKRARFNAIIPQQIHHAARHPVELDRRQSDAVEARIQLDLRLGAAFTRMQTKMLQNQVPDLQRKMISYGPCQFPTLGFVVSRYQQVQAFVPETFWYIYLSIMVDGEETDFTWRRGHLFDFPATLALYELCVESPEATIAQVTKKPTKKWRPLPLTTVELQKSASRLLRLTPKRILDIADDLYSKGFLSYPRTETDQFDPDFDFMTLIQKQTTDPAWGQFAQSLANGGFNAPRKGKKNDKAHPPIHPTAHVTNLVGDDKRVYEYVTRRFLASCSKDAEGQQTTVTVIVAGEEFNATGLTITQRNYLEVFTYDKWSDKQLPDFEQGQHFIPVVCEMREGQTSRPSLLTEADLVGLMDENGIGTDATIAQHIQTIIDREYVMTRQEDSMKYLVPSTLGIGLVEGYNKIGFDRSLSKPQLRRETEQRMVDICEGRSTKNDMLFQFIEQYREVFLRARAAFRQVVESVRDYLNGDGNVTEGGASSDGDDNDDFGGENGGRPPRGTRAPARGGNRGAGTRGRARGTTAPRTRGQPRGKGPSTKRRQDDDSDDENSRPPRGAGATAVSCRCDVPAVERTVVKETSNKGRKFWTCPNDPSCGFFEWADQASGGSASKTGASSRTIPAKRTHTVYARRCKCDLTAVSRTVVKEGPNRGRIFWTCPNSENARCTFFEWDDEQKEMSGPECPNGDQPTKRSRTAGTGTTRSSGRAGGRGRAKSTRGGTSRGSKRGKQWYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAI1</accession>
    <name>M5GAI1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627820.1">
        <property type="nucleotide sequence ID" value="XM_040777283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAI1"/>
    <dbReference type="STRING" id="1858805.M5GAI1"/>
    <dbReference type="GeneID" id="63692345"/>
    <dbReference type="HOGENOM" id="CLU_049056_0_0_1"/>
    <dbReference type="OMA" id="CSDTVIR"/>
    <dbReference type="OrthoDB" id="5588482at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="46484" checksum="C2ED9F88D84D241A" modified="2013-05-29" version="1">MRARDVEGIGIGRGWDWDWEGSVGLEEGGRREPRVGSASSAAREGKSKSATSGAEVPLVTAQVPRLLIVSLTVSTVSFTVCHPLFLVVGHLLDVPLLPLFTPYTPRSLPSLPSNKMFSLALLALLVVKATAQVPSSISNTCASYLTSLNTDSALSSCIQPLLSAASSFSPSSSSSTSQLSSTLTTLCSASPCSDTVIRSHLTNFYSSCQPELTASNTTSGTAGTAYAEVRQFYDVLYVINPLRSAVCSKDNSTGAWCVEEIAHDNAVAGNNTGGAGGVVNAAVAPSEQDKAIQLAQDYLYISAPTLVKRADSTSTTSAPLSTPSPLAGDNNILPNSTTYGSTNLAFLFLLPSLSSNLLCTSCTRTLLTSYIKWESSVPYALGLSNSQILGGQAALWNGVSATCGTGFVGDVEQGAGTVLGGSLSGALPLLSPEWAKAIAGVVAGLAALLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAK4</accession>
    <name>M5GAK4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L14b/L23e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_19907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632284.1">
        <property type="nucleotide sequence ID" value="XM_040771715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAK4"/>
    <dbReference type="STRING" id="1858805.M5GAK4"/>
    <dbReference type="GeneID" id="63686777"/>
    <dbReference type="HOGENOM" id="CLU_095071_3_0_1"/>
    <dbReference type="OMA" id="IRQSKPW"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006344">
        <property type="entry name" value="PRK08571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="14789" checksum="5E8D044B59EC61B4" modified="2013-05-29" version="1">MSKTTGAQGNKFRLTLGLPVGAVLNCADNSGAKTLFVIEPYGFGARLNRLPDAGVGDMVVASVKKGKPELRKKTMQAVIVRQRKAWRRRDGVFLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNAGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAR6</accession>
    <name>M5GAR6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629956.1">
        <property type="nucleotide sequence ID" value="XM_040771065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAR6"/>
    <dbReference type="GeneID" id="63686127"/>
    <dbReference type="HOGENOM" id="CLU_1219661_0_0_1"/>
    <dbReference type="OrthoDB" id="10621781at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="227" mass="25116" checksum="CA1A61496E3B6EB3" modified="2013-05-29" version="1">MATSGHDTGPNVQRVESSRFMLMENKTNQEKIVQKRKSSCARLETEFKKAQDACIAEEKKLSDICGRLASTEDELKAAQLLDAISHMLLQRTLSLNAERAMLNNSTSTHDQTKRGVSEQDSEDNAGDESPATEDIELESIGDEAEKSEENEDATPSEEVPNTPPSSQARKRTHSTGGAGQKTPQKRVRPSRSQCAKKKVRFFSPLVTFDERIEDLRDDQDDGSTAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAZ9</accession>
    <name>M5GAZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl endopeptidase</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_19397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Pro-|-Xaa &gt;&gt; Ala-|-Xaa in oligopeptides.</text>
            <dbReference type="EC" id="3.4.21.26"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S9A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632978.1">
        <property type="nucleotide sequence ID" value="XM_040771489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAZ9"/>
    <dbReference type="STRING" id="1858805.M5GAZ9"/>
    <dbReference type="GeneID" id="63686551"/>
    <dbReference type="HOGENOM" id="CLU_011290_1_1_1"/>
    <dbReference type="OMA" id="LDPWFSH"/>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070012">
        <property type="term" value="F:oligopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.120:FF:000001">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000005">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051167">
        <property type="entry name" value="Prolyl_oligopep/macrocyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881:SF2">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="9">
        <location>
            <begin position="16"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="8">
        <location>
            <begin position="533"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="741" mass="82705" checksum="03E90D7705CE8393" modified="2013-05-29" version="1">MAPPPPWDPKTTPYPSARRSTHVDIYKSVAKGEVRVPDPYNWLEENSKETEEWVEKQVEFTGKFIQQGPREQLYKAIKENFNYPRFSMASKKNDGNYYWYYNSGLQAQSVLYRASELPTGEALNSAGGDVFFDPNVLTEDGTAAITVAKFSKSAKLWAYGVSLSGSDFFTVYVRDTTAKWTGNPEDGKLKDEVRFCKFSDVTWTHDETGFFYQRFPTRPEHGAATEDKAGTETTMDTNAQLYYHRIGTTQAEDILVHEDPENEHYMWATTVTEVDGRYLLLSTSKDTGPTNRLWIADLKDAGVGPNLQWIKLVDNFKAEYSYIANDDTKFYFHTNLDAQRYRVISIDIAAAKPEWTEWLPEDPNGGKLENVIALPGNLFSVQYSRDVRDVVYLYNADAKPVQQIAEDFIGTIDTSGRRDSDELWLFMVGFTTPGAAGRWVVPTVARDAGVAKYGGWKPWRTTEVAGLRADEFDAEQVWYVTKDGTKIPMFVVRHKTTPRDGTAPAIQYGYGGFSISIKPSFAASILTFIKHFRGVYAVANIRGGGEYGEAWHEAGTRERKLNVFDDFIAATDYLVSTGIAGKGKVIINGGSNGGLLVGACVNRAPANTFGAAIADVGVMDMLKFPLFTIGKAWEADYGAPGDPKDFDFIFPYSPLHNVDAEKVYPPLLLLTADHDDRVVPLHSFKLAAELQHTKADNPHPLLIRIDTKSGHGAGKSTEKRIQEAADKWAFAAMCLGLDWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB46</accession>
    <name>M5GB46_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_53744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628075.1">
        <property type="nucleotide sequence ID" value="XM_040775201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB46"/>
    <dbReference type="STRING" id="1858805.M5GB46"/>
    <dbReference type="GeneID" id="63690263"/>
    <dbReference type="HOGENOM" id="CLU_012062_30_2_1"/>
    <dbReference type="OMA" id="DIEQECP"/>
    <dbReference type="OrthoDB" id="442970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="58" mass="6293" checksum="73BB8E5D219946F8" modified="2013-05-29" version="1" fragment="single">MSSLLPTNGRVLVDTTVGDIEQECPKACRNLIALALEGYYDGVIFHRVVPGFLVQTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB79</accession>
    <name>M5GB79_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1776-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632544.1">
        <property type="nucleotide sequence ID" value="XM_040771784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB79"/>
    <dbReference type="STRING" id="1858805.M5GB79"/>
    <dbReference type="GeneID" id="63686846"/>
    <dbReference type="HOGENOM" id="CLU_022674_0_0_1"/>
    <dbReference type="OMA" id="CHGYVRA"/>
    <dbReference type="OrthoDB" id="5308060at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013952">
        <property type="entry name" value="DUF1776_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="61760" checksum="D322E92F7360F968" modified="2013-05-29" version="1">MPTIDELEEYLAEVENYIASLLPALETLPSLPQRIFDELQRFGPPSLPAFPTLSVQVVPAPPPPPPPPPAPKGWCTWFGGMAGGGAMRRITVGVVVTASLGLASVYGYKRWRLHVLKKRKSRKLARTPLVTDGHRREAIVVLGADHPLGLPVCASLEKQGYIVIATTSTPSYASKLTKASSGYLRIVPLEPAEPVLSTAQANDGPSAFPSKLQVALSQRFPTNSAGDPYISAQHIPYVTGVVSLMSLPSPAPTPIAHLPMKEQYLPHLIASHFTPIMLLQSLLPVMHRSPLGRTPTIIALVPGLSSLPGTPFSGASSASTQATRSMLTSMRRELAQAHDPTKLMTLSVGTIALPSEGYDVTLPPEAKEAYGSALEAAMTSVGRRTWTNANRVTRVIGKIFQYSDTPLGTAFYWFKAGTVNVGAGANLYACAARLPAPVLDVLFAIPAWVATLRARLSFIPFVRPTFRRTSARVGREEKKPLSIAPAPIAAPPAPVLTPAPAAPVPTRTSAAVNVHVHDDAVSEPESDHSLEEHEHEHEHSESESDWEKVRDGEAASRVETPALAEPSEAKQAWQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBJ0</accession>
    <name>M5GBJ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar assembly protein DID2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_73740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633223.1">
        <property type="nucleotide sequence ID" value="XM_040776022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBJ0"/>
    <dbReference type="STRING" id="1858805.M5GBJ0"/>
    <dbReference type="GeneID" id="63691084"/>
    <dbReference type="HOGENOM" id="CLU_080826_0_0_1"/>
    <dbReference type="OMA" id="QQITMVM"/>
    <dbReference type="OrthoDB" id="10266568at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="203" mass="22628" checksum="B618A83EDD29BDD7" modified="2013-05-29" version="1">MSNLEKSLFQLKFTAKALNRQAKKATSDEKSERNKLKKALQQGNNDGARIYAANAIRKKNESLNLLRLGSRIDAVASRVETAVTMRNVTGNMANVVRGMDRAMESMNLERISLVMDKFESQFADLDVQTSYMEDTMNATTAVSTPQDQVDQLMQQVADEANIELQHELGVNDATKVPDLTVKDKVGEEEPNLAERLRALRPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC36</accession>
    <name>M5GC36_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_74090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633478.1">
        <property type="nucleotide sequence ID" value="XM_040776048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC36"/>
    <dbReference type="STRING" id="1858805.M5GC36"/>
    <dbReference type="GeneID" id="63691110"/>
    <dbReference type="HOGENOM" id="CLU_007740_0_0_1"/>
    <dbReference type="OMA" id="QCYQHVS"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="668"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="913"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="985"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="996" mass="109112" checksum="CF27CB6F97322F44" modified="2013-05-29" version="1">MEPAVAKGLNDKLYEKRKGAALELEKAVRDAQSHGDMLKIQQIVGQLCDLFASSSNPLHSRNGGLIGLAATSIALGVDVAQYLETIVPPVLACFSDPESRIRYFACESMYNIAKVSKGEILIFFNEIFDALSKLAADSETSVRNGAELLDRLLKDIVAESGPTYVPHFPETEKIRREKQSDGITGLGIALVSKEGFEPAGQPHNQHAFSLARFIPLLSERIYVLSPLTRSYLVSWITVLDSVPDLELVSYLPEFLDGLLKYLSDPTEDVRIATENVLADFLKEIRQIAQVQAQREGVRLRKLEKAKARRAEGDLEPKTPPQRTNGESGVYGYDEEEELVDDQGRGNGAWIPGQNVAVDHAAIVEILIAQLDTDHDEIQQSTALRWLTEFLSFAKEVLVPFTPRLILAVLPNLAHHVATIQAAAQMMNQQLFQVIQALPAPVTTPDVGTPQPPQVTLPPPPPPPTTALPSRAQSVASMNRTAPASPTFDGVAFPSRASRDSNRDSAGIDASATPVPARRQPAPSPVPSTSTAPEPSAAADGSTPSKAVVNTSAPLTESPPNLDQSIESPDPLDYQLTVNSLTVQFMSEHEETRVAALKWLLMLHLKAPNKILAMDDGTFPALLKTLSDPSEEVIKHDLRLLAQISSSSEDSYFKLFMVNLLELFSTDRRLLETRGSLIIRQLCLSLNSERIYRTFAEILERDEDLDFASTMVQKLNIILITSPELQEFRRRLKNLESKDGQMLFSILYKSWCHNAVAVFSLCLLAQAYEHASNLLQIFAELEITVQFLVQVDKLVQLIESPVFTSLRLQLLEPDRYPYLFKCLYGLLMLLPQSTAFISLRNRLNAVSSLGFLHIAPKTNVAAARSKLSRDEVKWQELLSHFRVVQMKHEKYRRQAAGGDVSPLAGLGLNSNGVPSAASRVQGRRVTAGSKDAPPVVRENAGGRLSSVLSPLNPRARGSSGGQTLAPLMSAFSGSPRAVSPTAAAATKRRGTLGGLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC89</accession>
    <name>M5GC89_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_116733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628545.1">
        <property type="nucleotide sequence ID" value="XM_040770255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC89"/>
    <dbReference type="STRING" id="1858805.M5GC89"/>
    <dbReference type="GeneID" id="63685317"/>
    <dbReference type="HOGENOM" id="CLU_792320_0_0_1"/>
    <dbReference type="OMA" id="NARACKK"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="200"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="36498" checksum="E435376D439D2F3D" modified="2013-05-29" version="1">MPSPPQTGYYRPPTRPPANSTVLPGIDELIRGMPRDQMPPEPHRPHAQAPDYTKIPGPPSPPWPNPPRRTDSPAYAYSQPQQQPRPVQGGPMYTPPSSGGSRPPTAPSHSQVSPQGHMVSQIPPHAGQMPPGTNPLPFPSVTYTSPLPPSPNTSTGASANVQAFPPGLPLDGPYYLPSHPYTTIYFAPPNQFGPARNARACKKCRQRKVRCSAAGGLGFAPGEPGMKCERCERAGEECIFEERQVGRRRTQGSGGSNGSGRSSGRSATADEDDEDDEESISTPTATTSTLRTPASSIAGPPRGSTKAGPPPAPSSGSGAASGGGVGRGNPAQGVIQGTQGYGRAQSMPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCD3</accession>
    <name>M5GCD3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_77569</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630711.1">
        <property type="nucleotide sequence ID" value="XM_040776276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCD3"/>
    <dbReference type="STRING" id="1858805.M5GCD3"/>
    <dbReference type="GeneID" id="63691338"/>
    <dbReference type="HOGENOM" id="CLU_001060_7_1_1"/>
    <dbReference type="OMA" id="PYCEKPE"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="23"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="434"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="789"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="888"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="436"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="827"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="855"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="954"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="970" mass="107976" checksum="3907CC8BF32C0AD7" modified="2013-05-29" version="1">MRTAVTELKGKEKEEKKGNRGTMGLANLGNTCFMNSAVQCLAHTEELAEYFLTGVFRTEINRTNPLGMGGQIAEAFGALMNRLWGPVTASNGSYSSGSSYSPREFKSILAKFAPQFSGYMQHDSQELLAFLLDGLHEDLNRVLTKPYVEKPDWPGKGGPKELIAFAKECWDGYLKRNDSVIVDLFQGQYKSTLVCPECAKVSITFDPYMYLTLPLPINRKWRGKVHFIPWALDKPRQRLTLELPKEADFKRLKQHVGALTGADPTCLIAAEPYQHVFWKFWEDVAPVGDINTGSDDVAFYELPCALSQLRATSTDRSSPVRLVDSGWILVSIFLSASRPRHNPESRFGSRRYLAHDKFPLIGQPFVLALTRQEASSEDVIYDRIVQRVSQITTRKVELYDDQALPVTPALTNKDQMANQAETPDVDDLFGAHENADASTSTSAAQTANRQSVKVTNGQHADHQRSWTARKDMFKMHILQHLRDLGEGHLVTGWSIEATNRIVEFEDRKQDVSGAVRVLPGGFKEEIEEEEDLAVQGSADDPYKPLLKQGEAIMCEWNDDAAQYFFEDPYTTWDEFEDIVDPTIATSDEAEKTAGKKGISLYDCLSEFTREEQLGEDDLWYCPQCKKHQQATKKFEIWSVPDILVVHLKRFSSGRLLRDKLDMMVDFPLEGLDLEGRVEEKLEWKRMREAEGKANEKNGDPEEEPITYDLFAVDEHLGGLGGGHYRAYAKNYADGLWYHFDDSHVTQADPAAAVNRNAYLLFYRRHTSRHLGGKTWGKVMAVRTAGPVAGAEAPEQQVKSMNPFRGTDVKRPEFGPALPFPRLVPAKSGMISPASSDSSDSGEGPGYSPPSPPPFDLSGNDQLLLNGNLDLEDNDDYNGQLIVRGAAPSPFGGSTSAEMGDSGIITPADSEMDNAEASASSDPWADEEPSQAGRYAPAYDDDDLIKGYLPTPPDVDMKSVEGEKAQPRSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCF0</accession>
    <name>M5GCF0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628620.1">
        <property type="nucleotide sequence ID" value="XM_040770153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCF0"/>
    <dbReference type="GeneID" id="63685215"/>
    <dbReference type="HOGENOM" id="CLU_1896147_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="134" mass="13005" checksum="5B4BE7C7064687E0" modified="2013-05-29" version="1">MAELRSLLPKLRNILHIQALSPPPPPTSPPAVSGSGRRQGPIVPVDPPPKSAFCRGRDRQRTSQGGDADPSSGAFTGGNGNGSGNGNGNGNGNGNGNGNGNGASAGGTPLSPTCPSRSTVPAASAAAVVVPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCK3</accession>
    <name>M5GCK3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_107556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628720.1">
        <property type="nucleotide sequence ID" value="XM_040768500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCK3"/>
    <dbReference type="STRING" id="1858805.M5GCK3"/>
    <dbReference type="GeneID" id="63683562"/>
    <dbReference type="HOGENOM" id="CLU_1189985_0_0_1"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF27">
        <property type="entry name" value="ACL091CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="25178" checksum="A54BDDC4B8BB9612" modified="2013-05-29" version="1">MADELQASEDAGQRVWIIGHVPPGWNGNQALPNPTNLFYQIVDRYSPHVIAEIFFGHTHEDEFSIYYANNGTNISATSALTTAWTAPSLTPLSNLNSGFRAYDVDPVTFNIVDSFTWFSNISAAPVLDNQTTYGPTYTFEYSAREAYGANISWPTDAPINATWWHLVTEQWQINPSLVGKFTVYEGKSSVKTTNCTSTACVESKICYARSASVPIAGLCPYGSTYGSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD52</accession>
    <name>M5GD52_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF21-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_105325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
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                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
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                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
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                <person name="Eastwood D.C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">DJM-731 SS1</strain>
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        </location>
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        </source>
    </evidence>
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</entry>
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        <name evidence="2" type="ORF">DACRYDRAFT_62735</name>
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        </lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE42</accession>
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        <submittedName>
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        <name evidence="1" type="ORF">DACRYDRAFT_106136</name>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
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                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Kohler A."/>
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                <person name="Kumar T.K.A."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040768202.1"/>
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    <dbReference type="AlphaFoldDB" id="M5GE42"/>
    <dbReference type="GeneID" id="63683264"/>
    <dbReference type="HOGENOM" id="CLU_2084766_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="117" mass="13181" checksum="52E6BAA649D9CD84" modified="2013-05-29" version="1">MEFIIRRKTWIDSEKLLIPVKALVSRGNLSRFEIRPDRIPTSTRSVIVLPQDALAELDYEKEVCDLRPLDQSGPHPSAVPEAQDIPVAWSHPIPRWAIRFQPCGTSPAMPSKCLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEE9</accession>
    <name>M5GEE9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630077.1">
        <property type="nucleotide sequence ID" value="XM_040772405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEE9"/>
    <dbReference type="STRING" id="1858805.M5GEE9"/>
    <dbReference type="GeneID" id="63687467"/>
    <dbReference type="HOGENOM" id="CLU_107716_1_1_1"/>
    <dbReference type="OMA" id="RGGFTQW"/>
    <dbReference type="OrthoDB" id="102559at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF38">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="134" mass="15430" checksum="0829277154A5D198" modified="2013-05-29" version="1">MSFSRPCSFISPKELKKLLSSTTDKPTVVDVRDDDYLGGHIVQCLHYPSSRFHSDVHSLVEELKDEHVVVFHCALSQQRGPKAARIYAETRAILLPEAAEQKVVVLRGGFMQFQAEFRNEPHLFEDFRPELWDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEN2</accession>
    <name>M5GEN2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632451.1">
        <property type="nucleotide sequence ID" value="XM_040767869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEN2"/>
    <dbReference type="GeneID" id="63682931"/>
    <dbReference type="HOGENOM" id="CLU_994048_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="280" mass="31017" checksum="93A226209F7728D7" modified="2013-05-29" version="1">MPSAKLRQMYAHLNTTWCMKIEWELFQHPMTFKEAEQVWLVAQCKRHKAVKAQLAEASKPDATAVVSDVPMASLFMDRQVAQMHVGVLRANAGFRPSTAFPVAQASTSQPNIMPAAAFHDYLGYTPGAESLPIPSKLGANMTTKSMAASLPSEKLLTALDLHANPAFVKKYAEPYWTVMKEHKRSTSLLRELEEVLLPILGSLAKQLAAAQCPTDVVGFPSTLLGKEAAEDWQKAKEKMEREMEKLEKQREKEQAMWDAALATGEGGVYMQTSTGTPFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GER7</accession>
    <name>M5GER7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription factor IIIC 90kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630412.1">
        <property type="nucleotide sequence ID" value="XM_040768130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GER7"/>
    <dbReference type="STRING" id="1858805.M5GER7"/>
    <dbReference type="GeneID" id="63683192"/>
    <dbReference type="HOGENOM" id="CLU_008513_0_0_1"/>
    <dbReference type="OrthoDB" id="421374at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044230">
        <property type="entry name" value="GTF3C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024761">
        <property type="entry name" value="TFIIIC_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12657">
        <property type="entry name" value="TFIIIC_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="1">
        <location>
            <begin position="29"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="719" mass="77586" checksum="C1A188FE9A67184A" modified="2013-05-29" version="1">MVWKPDIHIAVELSAPPARSCPTAIQQNEDGQFGVLIKEGIHILTPDIGLAYDPGTADVATVPALRKPDREPLKVYRAVAEIALGDHIAWADESLDMATMVPGSVSIQCKDFAWSPIGLGQDGRCLLAVLTTNLEVFMYGAGKNYVDGQWLRVFTLTDALLETAKSSAINGKAKVSSLRRTLQAQTTALAWSAAVRASGVPSSRDLSLLALGSRAGTVSLWRSGKRQATVVLGEEWVAHLSWAGWLQMDADTVASVLACGLSDGSVHLVTVTQKITDHSFDEVQAVPSPALVQPDLRGLTALRWVYLQTYPLHVLVYAKPGLLGLIAPTGSGLDWVGERRLVVQKQPVFLGSTALGIPSGLDYLVKEDALLVSYSDGSIHVIHSVSTDPTLEMPGSRLQSAEITRAMRRTCMDIEGPGTPHVAVMQTFGCHLVSSGVALWSYQKTLPTFIDYVPEFGQITSVTLAKLFDPSHDTTQSLQNVQSLCFRPTPPFGPPVRLAPKLLPIYLDLEANRNSDAIRSELDHLLDASPSQSTDASLSRSSLTWKTPDTEDLLRCQLIVDLIDGDEITTLRNKLAILKLANKFGYSFADRIPYVQTLILALIFAALSYTAADPSSLLLANDPVFARRIVSISQCMPISIGTDVAVQALAASNKVDQLMPSSTETDGNSDGIELNGSIDVGDICVVCKASMPVRSLEMAHCSNGHVWGKFFRSFSSCEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GES4</accession>
    <name>M5GES4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630432.1">
        <property type="nucleotide sequence ID" value="XM_040768132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GES4"/>
    <dbReference type="STRING" id="1858805.M5GES4"/>
    <dbReference type="GeneID" id="63683194"/>
    <dbReference type="HOGENOM" id="CLU_024142_0_0_1"/>
    <dbReference type="OMA" id="SEYYTHQ"/>
    <dbReference type="OrthoDB" id="3357341at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="600" mass="66350" checksum="41270F1E2F34C6A3" modified="2013-05-29" version="1">MALDANLFTLVLTPAKGEPTVVDLVDPHGEVHYRKRFISSQPTYQMSIFDPHTDALLCTVAGTNPAAKQKTIELFNPNVTVSFQNTGTLSFKWSFTWEQHEFEWKKEACFLIRKPDPPVIVCSCDAPQTSKRSALQILDYNLQRFDIDDRKGLEICIIAGLLSFYDQQDESNRVRQPERRGPLPVVPSTAQPELRPHPSQESLDIKKDLPPPPPVPIPRDGNEIFIIDDVPVHDYVQQCAELLLDENILFIILRAQSTTAVPKCVTVAEEVKRWIYRSTDEDQELHQYVTTDEKVDGRGKGRGKHRINLDEPVNNPKHDYHPLGPPQTLTIHLSKIPMPELQPKAAPKPPTIPRAPPIAQYVPPSGAPPNLSPSEPRNRLTKADKGKGRTAELLPLPNTDRKSEKAKGKQRAESPPPDPAARVDKGKGRENPTPMLFSPNPSSFPAAESRPDKGKTRADDPPPARGRTHRPSPSVPQLRIDTSARPASAPTQPRPLSYQPNSVSQRPPANSQQYPLPPQPNRQGYDNPNSVSRYPQSGPQPYGIAPGPYAVYGTSSGAVKVAGQGAYLAPYPPGTQAQGTRPQSDSGGSMFDKIFRPRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEZ4</accession>
    <name>M5GEZ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_45973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632741.1">
        <property type="nucleotide sequence ID" value="XM_040774676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEZ4"/>
    <dbReference type="GeneID" id="63689738"/>
    <dbReference type="HOGENOM" id="CLU_762954_0_0_1"/>
    <dbReference type="OrthoDB" id="2574879at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031349">
        <property type="entry name" value="Tfb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781:SF1">
        <property type="entry name" value="ADR380WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781">
        <property type="entry name" value="TFIIH COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17110">
        <property type="entry name" value="TFB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="39520" checksum="4CF4A59C0390021E" modified="2013-05-29" version="1">MSGGFIPPSPSAASSITLRDGTPAPAPLHTALSAAQERRLIGYLDDHFLSINRAYKKRHEPDAPLPSLLSYISAFRPLLALILQIPPLDPSAALRVSYLLRLTGDFTDTLPGYGVPLSTAGDTLDELVSFLTHLDKGWQAVLSSERWDPASHTGVPMTGGESGALSRPVSATDKIRLRSILQSGRERIEQWARGVVHVDPGTEVDVASSFWRTLAALGDVPLPERGGDMEDEDAKELLEVVMVCYSLIAVQVLMITGGRARIRDVTRNGSPRILPPLLKGNLLPVRPKHDNASLAVEVDRDGHRSHTRRSIEDGILPRPVIDIISFLHQRLFPLLSLSQPVLLGLLPLTFLLAQSLVHPVLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF55</accession>
    <name>M5GF55_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="6">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_64959</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="6"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630752.1">
        <property type="nucleotide sequence ID" value="XM_040775766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF55"/>
    <dbReference type="STRING" id="1858805.M5GF55"/>
    <dbReference type="GeneID" id="63690828"/>
    <dbReference type="HOGENOM" id="CLU_004624_0_2_1"/>
    <dbReference type="OMA" id="GWDMQDL"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF42">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067715" description="glucan 1,3-beta-glucosidase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="125"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="468" mass="51051" checksum="066B4D4E9B51B98C" modified="2013-05-29" version="1">MRISLFSYALLASTALAVPCCTLRKKGSLRPSPPGDASPASSSSASSASASPASSASASPAPSPANTTSTPSRHSGFAYGSTPVRGVNLGGWLVLEPWITPSIFDNTGNDGIVDEWTLGQYSDYDTALNTLRNHWSSWITKSDMQQIAAAGLNHVRIPIGFWAFDNSGTPYIMDQQYSYLKQAVQWASASGISVWVDLHGVPGSQNGYDNSGQRGTPTWHTEQSNVQRSQAIIQTLANEFSQGQYGGAVTAIELVNEPAGYYSEDLLTCARNYYGSTYTTVRNAGNLVVVLHDAFQSLDYWNGFLTSNTGASNVLMDTHIYQVFNTDQLQESWQGHINDACSNGARLASFAEQNLWTVVGEWSTASTDCAVNLNGRGVGARYDGTYPGSSYIGNCYGQTGDQSTFSADYKTFLRQFWEAQVTAYEQAQGWIYWCWKNEQADDWSYQKGVQNGWIPSNPNNRQYPNICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFS1</accession>
    <name>M5GFS1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_20924</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631267.1">
        <property type="nucleotide sequence ID" value="XM_040772146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFS1"/>
    <dbReference type="STRING" id="1858805.M5GFS1"/>
    <dbReference type="GeneID" id="63687208"/>
    <dbReference type="HOGENOM" id="CLU_005470_1_0_1"/>
    <dbReference type="OMA" id="CWAEGVY"/>
    <dbReference type="OrthoDB" id="332281at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024603">
        <property type="entry name" value="COG_complex_COG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024602">
        <property type="entry name" value="COG_su2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12022">
        <property type="entry name" value="COG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06148">
        <property type="entry name" value="COG2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 2 N-terminal" evidence="10">
        <location>
            <begin position="58"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="COG complex component COG2 C-terminal" evidence="11">
        <location>
            <begin position="509"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="612"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="871" mass="97238" checksum="BF5069BC071B2664" modified="2013-05-29" version="1">MNAVLTQGQDDPLTLDLLSSELHSHPGSPDSPKIDLPILLPLSHNHPHLDVSSHDRPFEVDEFLLTRASHTTLPDLRTELRDYLAKLKEELVGLINRDYGDFVSLGTDLRGEGERLERLGKPIPGMKQEVEKAKGELDDVKAAVRDRLTERAALREEKALLQLLLTLSDSLVRLESLLAIASPPSEDPDMPTISGKMDFVAPVTSRGGKHLARVASEYLQLLYHADKARGEGCAFVDSNRWRIDRIKTTLSRDLDNLFTTLLTSSASQQTNEGFFASNTTDRGRRMPELNEVLRTYDALGEWRQAEEVLRREVVRPFIRSTLHSTALTAPLSPLLPRTPFLLKSFKRTSITEALISPPLITPGTGTPGLMGAFNPQAPLLLTEDTPLAAVYNQLLRFADRELAGLIDASERISNAHKGRRNPNETPVENGKPEESDNRFEFLANVFWAETAGALMDEMGGQLFAAGRPDEFLVNYHTTSAFLHSLESLAPSLTSVFTIRSHPARKAFDRRWQLPVYFQLRWKEIVGGLEDALSGNPITGDNWEGFKSPQSDAVWKALERCWSEDVFVLELGERFWRLTLQILSRYRTWLAETAPAEILDRPALSLAEKRSASPALSGVPSRSSTPHPPTTPDATKDSGADDDETLRKDAYNIIDMKHLEEKVWDLYDRIGGLLEEAEEDDETAKETLQSSLAHLLSRIPSYQTQILQILTKRCADPLRHVRSIASQYRAMSNKREPTEPSYFVPGIMRPVKLFFDKGGPGEALKGSYGSAWATEIFDDLCQRYTAILVDMKKTEDSLRRFKQGKKSAFSLFGSSTASAKEEEGKDEERVKKQMFLDVTALGKDAETLGVDARTSESFKGLMQTIGMAEATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD6</accession>
    <name>M5GGD6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">26S proteasome regulatory subunit 7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_113461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632197.1">
        <property type="nucleotide sequence ID" value="XM_040769634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD6"/>
    <dbReference type="STRING" id="1858805.M5GGD6"/>
    <dbReference type="GeneID" id="63684696"/>
    <dbReference type="HOGENOM" id="CLU_000688_6_0_1"/>
    <dbReference type="OMA" id="RSKYHIE"/>
    <dbReference type="OrthoDB" id="1937997at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000440">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="229"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00067449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="454" mass="50584" checksum="CC0DBD521C418D8C" modified="2013-05-29" version="1">MPPKSDWEKYEKKIDDKDDEKIVALDEGDIQILKTYGQGPYGLTLKKIETDIKEIQKRVNEKMGVKESDTGLAPPNLWDIAADRQRMGEEHPLQVARCTKIIRADPEVVEAANAEAIGPGDRIRGADEVDKYVINIKQIAKFVVGLGERVAPTDIEEGMRVGVDRNKYQIMIPLPPKIDPSVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLNPEKFVNLGIDPPKGVLLFGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARGKKACIIFFDEVDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALLRPGRLDRRVEFGLPDNEGRAHILKIHARSMSVERDIRFDLIARLCPNTTGAELRSVATEAGMFAIRARRKVATERDFLDAVEKVVRQGTKFSSTPLYQVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGM7</accession>
    <name>M5GGM7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632652.1">
        <property type="nucleotide sequence ID" value="XM_040767896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGM7"/>
    <dbReference type="STRING" id="1858805.M5GGM7"/>
    <dbReference type="GeneID" id="63682958"/>
    <dbReference type="HOGENOM" id="CLU_023205_1_1_1"/>
    <dbReference type="OMA" id="WCVHHSA"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="299" mass="33301" checksum="233AC1B2EE568E68" modified="2013-05-29" version="1">MVHSRVPLLFGTASIGAPGQAAVRVSDLDTAQKMLHVFLLKYNYRELDSARVYGGGTTEQYLSQLELRGATVDTKSYPSAPGDHNPEKLRSTLLESRKALRNLPIRAFYLHAPDRSVPFEKTLEEVDKLYKQGHFEIFGLSNFASWEVSAICEICKANGWVKPGIYQAMYNALQRSIEPELVPCLRTYGIRLVVFNPLAGGLFLGKITSIDQLPNEGRFSGAGAFAKLYRERYVKEGYLNALEKIKIVGEKHSLRLTEVALRWCQHHSMLTESDGVILAASSTEQLEMNCADSEKGIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGM8</accession>
    <name>M5GGM8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding TFAR19-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632657.1">
        <property type="nucleotide sequence ID" value="XM_040771816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGM8"/>
    <dbReference type="STRING" id="1858805.M5GGM8"/>
    <dbReference type="GeneID" id="63686878"/>
    <dbReference type="HOGENOM" id="CLU_122978_2_1_1"/>
    <dbReference type="OMA" id="IVIQMAT"/>
    <dbReference type="OrthoDB" id="10252486at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10335" checksum="F6A98D23025B99FE" modified="2013-05-29" version="1">MKRGMLATILDAGARERLARISLVNPTLSKRVEDSLLRMAQSGQIRTKVTEQQLISLLENADGNGQSSHAPKKTIVYSRRKHDEDDDLDFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGN1</accession>
    <name>M5GGN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SRR1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SRR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040771823.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="SRR1L"/>
    </dbReference>
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        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="219" mass="25218" checksum="057F7810F128E86C" modified="2013-05-29" version="1">MAEVERALEKGDWYQAFLGVLETFESQCTIKPTRVLCLGLGSPTDWSPAQYQLALLMRLCQHFNIPLERAEVFDPVFTEEDEDYLRSVGLTVPSEDKDARYELLEPTLVYMPHCDLIYYNYLLEENWSAERLGNLLMLGNNLEDYVTMGPMKRLRVKGPLVEKIVPYINATSFPPKFELESGAFNDTQFQFVKLSELPSKGDDFWKLDARETERTAIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGN3</accession>
    <name>M5GGN3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_20168</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632682.1">
        <property type="nucleotide sequence ID" value="XM_040771828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGN3"/>
    <dbReference type="STRING" id="1858805.M5GGN3"/>
    <dbReference type="GeneID" id="63686890"/>
    <dbReference type="HOGENOM" id="CLU_000604_57_1_1"/>
    <dbReference type="OMA" id="EQFYCTA"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067837" description="ABC transporter domain-containing protein" evidence="10">
        <location>
            <begin position="18"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="760"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="847"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="992"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="398"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="668"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="682"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1018" mass="108455" checksum="EA652C267E4DD9D4" modified="2013-05-29" version="1">MLLFHLLLLLLLVPALSQSCEQYALPQTSTTCLCPPGFSGPTCSFPSCGGNLFQGSTRASAQPAQGQQYSNLTSSGCTCQSGWGGEGCNVCLSAGACQSGFWASNFNTTVGQSTPDLSGVSPDQTGNQTITCSADSRVYTSAEMSCDVNNPTLQSLFPLQSSLTILRVLNPSLSLYPNVSSLPVPNATIFAQLWYAGVEQFFCTASSCSQTLDTNGPGSTDWMCNDLECHCRAGTDFCGATAAMNLTGTIDQLGGTLEIACDAVTSSTGAGCTFKQTTLDQLFGANGLSLQNCIFGECVRQGVIDNALVNSNGTSTTTASSSGLSGGVIAGLAVVGGIVLAAILLLLWGLWDQRQARKGAAAGAEAALATEKPPGGIGLQFTDLTYIVPLRSRLSMFLRGRRAAREDATSEDNELPDGSGKWILRNVSGRVEPGQMVAILGPSGAGKTTVVELLAGKRKTGRSSGSITFFSGADGHPLERIPRVGFVDQADILPSQLTVRETLLFAARLRLPETMPDASKQARVFEVLDQLGLSHVAETRIGSGERRGVSGGEMRRVSIGCELVARPAVLILDEPTSGLDSVSAQKVASVLHDLCHDPHNPTIVIASIHQPSSKLYRTFDKVMLLSEGKSLYYGEGGNAAAEYFAGKGLPCAQGYNVADHLLDIASAPPPSLMDAPPAQAPANASTESNGLRHTPSEEGEKSLPADHPLAFAHNRADEIPPPGAGIDRGNLRTSGRYAATFLTQLEVLSGREWKNLCRDWSLFFAHLAVSIVLGVFTGGLYFKTGITIAGFQSRIGCLFFLGSLLSFTALSALHNLSVIRPLFLRERAGGYYSPTAWLLSRVIWDVIPLRIIPTIAVSTITYWMTGLSPTPANFFKFLLILILYALVLTLFNFFYAAIFSNGGIAILLSALFNLAQMTFAGFFVHLDSIPPVLRWLQWLCPLKYTLEALSVNEVNSGLMIQDTLSGVPVDVSAQLIMNLLFGFGDSNYYRDVLVLFAFIIGFGIATITAVWFGLRETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGS4</accession>
    <name>M5GGS4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">H-sco1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_19330</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632887.1">
        <property type="nucleotide sequence ID" value="XM_040771456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGS4"/>
    <dbReference type="STRING" id="1858805.M5GGS4"/>
    <dbReference type="GeneID" id="63686518"/>
    <dbReference type="HOGENOM" id="CLU_050131_0_3_1"/>
    <dbReference type="OMA" id="MLYFRVE"/>
    <dbReference type="OrthoDB" id="270009at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000013">
        <property type="entry name" value="Blast:Protein SCO1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017276">
        <property type="entry name" value="Synth_of_cyt-c-oxidase_Sco1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037736">
        <property type="entry name" value="SCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="104"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="142"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="30989" checksum="AD1165E6E1F45438" modified="2013-05-29" version="1">MSCQRVALRSLCDLDLLLSRKPLLSLRRITGYHRPAISHSLRVCRYTTGPESEEQQRDQSAVGPFTWKAAGLFVATGAGLYWYFTNEKTKLQEHKRKQQAESKVGKARVGGPFALVAHDGTPFTDKELLGKWSLVYFGFTNCPDICPDELEKMTEVVETMDAEFGPVVQPIFISCDPARDSVQQMRDYVSDFHPRMIGLTGTYDEVKATCKAYRVYFSTPPDTKPGDDYLVDHSIFFYLMDPKGEFVDAFGKSSSADDVQQKVRKAIQEWRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNE5</accession>
    <name>M5FNE5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_59376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624203.1">
        <property type="nucleotide sequence ID" value="XM_040775558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNE5"/>
    <dbReference type="STRING" id="1858805.M5FNE5"/>
    <dbReference type="GeneID" id="63690620"/>
    <dbReference type="HOGENOM" id="CLU_046006_22_1_1"/>
    <dbReference type="OMA" id="EESQCGW"/>
    <dbReference type="OrthoDB" id="10255422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33990">
        <property type="entry name" value="PROTEIN YJDN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="PhnB-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="16180" checksum="6D27E5D299F577E6" modified="2013-05-29" version="1">MGTSPPKVQTFLWFDTSAQSAASFYQSAIPGCTLLSQNQMSVTLSLSGHELILFNGGPSHALSPAVSLFLTCSDQAEIDDLWAKLRDGGEEIACGWVKDKFGLCWQVVPRGLDKLVFGSGRAMQVMRGQKKLEIEPIRKAAAEDGVFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNK1</accession>
    <name>M5FNK1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase NM domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_119255</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624483.1">
        <property type="nucleotide sequence ID" value="XM_040770755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNK1"/>
    <dbReference type="STRING" id="1858805.M5FNK1"/>
    <dbReference type="GeneID" id="63685817"/>
    <dbReference type="HOGENOM" id="CLU_018204_1_2_1"/>
    <dbReference type="OMA" id="WNMFLSK"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="64"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="272"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="50463" checksum="ACC508FB23272083" modified="2013-05-29" version="1">MSTYTHPVAAVTSPAAWALIEDKFRPHAKEMLAKLVDFVQNEVVPAERVYLAQIPTDPVKRWQTIPPILDELKTKAKKLCLWNMFLSKTHYPDVGIDLTNLEYALMAEVMGRTGALASMATNCSAPDTGNMEVFARYGTPEQKKKWLVDLMAGKTRSSFSMTERFVASSDATNIRTSIRKEGNEIVINGHKWWISGAGDPRCAVHLVMGKSDPTNPDRYKQQSIVIVPVNAPGVRVVRPMTAFGFDDAPEGHCEVIYENVRVPESNLIAGWGRGFEVIQGRLGPGRIHHCMRSIGLAQRALDLMLERITDPTRKTFGKYLHEHGTIVSNVAKSRAEIDSARLLVLSAANQIDRARAKGAMKEIGIAKFVVPSMALDVVDRAMQSFGAEGISQDTPLAYFFSGLRQLRYADGPDEVHIQQIGRKEIERAPELVRLSQVAARKEKQLFASAGLEARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNS7</accession>
    <name>M5FNS7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624778.1">
        <property type="nucleotide sequence ID" value="XM_040769226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNS7"/>
    <dbReference type="GeneID" id="63684288"/>
    <dbReference type="HOGENOM" id="CLU_011584_1_2_1"/>
    <dbReference type="OMA" id="FIVIKEC"/>
    <dbReference type="OrthoDB" id="312874at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="385" mass="43401" checksum="B4B51F6E9737692D" modified="2013-05-29" version="1">MDRARRYFIPIITSWAVQDVVQGMIMTPGDVEDDDPNSSAGVFELPRNVAYDQLASATRSLGTSLSGSYPPVTAVTRRANGTPRMQRQRWRTVYGTVGIPLNNVSNARHVSIVLRDCSAALMLLTQAEYRHRDISLYNMYLVEEKVKEPSGALSDLEYAADWNSRTALHTIRTGTPIFMAAEKLLGRWLYLPDNDDDDESGTDELSDPFTRARTIFVPPSADQAPQVNMPKPKSWVTPLHDAEDLYWVAVYKLFYSVPAANPVPAPRQVEIRNLLFGFGPDTTINRKDFISRGRLSDPWKPEATDEEMVPAAFLPWWLSLKGVGKAIKKAHYPYQASWSNDVFYPNLQRTFLIYTKLVDAMPTDLEIAVYPDPKEDAARINKSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNT7</accession>
    <name>M5FNT7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63689311"/>
    <dbReference type="HOGENOM" id="CLU_1294369_0_0_1"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="213" mass="23078" checksum="EDB0DB103A210643" modified="2013-05-29" version="1">MSQSALSPHHRYHHPPMAGLRPCLKPATPSPVASMPSSPCSTPGLHQRVVHFPAPANLHRVHPAHSGLEYDRTPIAPPSESERACAMPARGCPGKTYESAAIDGRFVRPSASALQGAPPPLTFSGSSSEESDEAYSYMHEHDPVPAYTFSASPRPLEMQFLPHAPSKRRSNSPARTEEDRRKELPKKRVACKAPGAQWCEWNADDDGGCLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNX6</accession>
    <name>M5FNX6_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNX6"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="214" mass="22836" checksum="5896E53F1F0CAC2B" modified="2013-05-29" version="1">MAPIVSQEVIVAAPAQDLLRRSEYAYTHASPFLMQEGGGLSAFVPSEGDDSDDYDFNELLKTENEILVEVLHAVRPSVLNGSPAADDVFQAIKEWFIQLWETISGFGSRMWKPIADKIAEVAGQVESFIRAHPKEIAYTVGGVLLTVALIIFGGPAILTLLGFGIWGPIAGSLVAVLRSIAMGGSVLLVANLQITAVVCFIVGLALILYSALHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP86</accession>
    <name>M5FP86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_57499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP86"/>
    <dbReference type="STRING" id="1858805.M5FP86"/>
    <dbReference type="GeneID" id="63690512"/>
    <dbReference type="HOGENOM" id="CLU_170045_1_1_1"/>
    <dbReference type="OrthoDB" id="3208495at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="70" mass="8199" checksum="77D8B76D866E3B48" modified="2013-05-29" version="1" fragment="single">LSHMKSIIMHAAWRTLLNCEFVEAYQHGIPMLCADRHQCHVYFWIFTYCADYPEKMLIATICTLGEMPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPP6</accession>
    <name>M5FPP6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112658</name>
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    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623447.1">
        <property type="nucleotide sequence ID" value="XM_040769462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPP6"/>
    <dbReference type="GeneID" id="63684524"/>
    <dbReference type="HOGENOM" id="CLU_1586425_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="18990" checksum="C6F8C25CB2851335" modified="2013-05-29" version="1">MLPPSPDSDHPAVDTSDEYEYSEGSDGTVNELKGWEELDSTPKLLGSTSSQSEPNERSQADLKQRWEGGIRVETFIGGEGELRTVYGCRSVEEAEKSIKDWPKPDKKRIYNARVFVVEHDEKTNQFSESMVGIVFPSRFGRTPSGSKLYVYPPEDRAAEEVAWRELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPQ0</accession>
    <name>M5FPQ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624126.1">
        <property type="nucleotide sequence ID" value="XM_040771409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPQ0"/>
    <dbReference type="GeneID" id="63686471"/>
    <dbReference type="HOGENOM" id="CLU_683384_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="403" mass="44866" checksum="CADE43538F9E3E4D" modified="2013-05-29" version="1">MPPRRTNTINTAITNVNAPHSSLAMWRKEEADQWAALCKFWSVDDREHPAWAQNKDDLGTYRDVAHKYIGDFTGDVLCWMTKGMVEHLGPSAQAMWIHMHMNRHGVVEADYELNIPELPSTAEQAILHNVEGATDPSPPPPPQPKPTAAKRKKPLNLVSKVTITMEKAPHHYPTCQNCGCPQKSSSDSMDAIEPLPKQRKTAAGSKKTPALLATNNNNNGNTANNDDPETQDQQTANDRSSQEKSTEEGGNKQDDKEDEEEREYCVTRDPMNAMSSLMDLVEDGVYHCNANNIKNKAIPPPPPEGKWLYFPVACEPCHQNHMKCFRLPGISKKCYNCCIKHGKCCNVGLLDGCLHCTAVKSKRTKGQITQEIKALQDHLKDLKEECKEAPDTESESEGSGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPX4</accession>
    <name>M5FPX4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_96514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Cd(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48775"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625738.1">
        <property type="nucleotide sequence ID" value="XM_040777381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPX4"/>
    <dbReference type="STRING" id="1858805.M5FPX4"/>
    <dbReference type="GeneID" id="63692443"/>
    <dbReference type="HOGENOM" id="CLU_026885_0_1_1"/>
    <dbReference type="OMA" id="FKVMMQM"/>
    <dbReference type="OrthoDB" id="2338at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0104">Cadmium</keyword>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="506" mass="56167" checksum="A1604F0595F65B2C" modified="2013-05-29" version="1">MAEDWSPSSWRIKPIAQDVKYTDKQHLARVTDQIKHLPPLVTPAEIERLRYHLSRVESGQGFILHAGDCAESFEACTHRNITNKIGLILSFSLVLLWGARVPIVRIGRIAGQYAKPRSSSTEVVDGKTVLSFRGDNVNGISPDDREPDPQRMLSAYFYSTTTLNYVRALLTSDFASLHHPRTWSLKHVRSPTLKCEFENITNALSDALAFTQTVGAIGGVDEGGYVQGGGRGVLGEVDFYSSHEGLMLDFEEAMTRFLPIPAGTLSHTDAKKPLPPKTYYNTSAHFLWIGDRTRQLTHAHVEYFRGIRNPIGIKVGPSMKDDELARLLDIVNPDKEHGKVTLITRYGAGKVETHLPGHIAAIRACGHPVIWVCDPMHGNTHTSSTGYKTRHFSSIITEVTSTLALHAKENSRLGGVSLEFTGELNEQGFSVTECLGGSMQLGEEELELRYQSYCDPRLNFEQALDLAFLLSDHYKQARENTIKPQPTTNLLLQELGKTVNGHAANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ37</accession>
    <name>M5FQ37_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_56765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625853.1">
        <property type="nucleotide sequence ID" value="XM_040775393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ37"/>
    <dbReference type="STRING" id="1858805.M5FQ37"/>
    <dbReference type="GeneID" id="63690455"/>
    <dbReference type="HOGENOM" id="CLU_012368_2_0_1"/>
    <dbReference type="OMA" id="SVYESCP"/>
    <dbReference type="OrthoDB" id="10252281at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="6">
        <location>
            <begin position="139"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Asparagine synthetase" evidence="5">
        <location>
            <begin position="500"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="67323" checksum="4F371D229D8233DB" modified="2013-05-29" version="1">MCGIVFSLRWCPTLSEGGKGFGTEGEEDRQGRGEADGEEEEEWARLCALNAHRGTAYSFPPRPSLLRPLPSDHNPDPGPDHQAEHTVNLALPGCSVKLRFFSSVLHLRGELTPQPLRLVAGGDVLCWNGEVFEGLPVGDENDTAVLFRALQAGDVHSVLGQVEGPYAFVYLDRGRKKLYFARDPLGRRSLLLHQTGESLLLASSGLGKSLTPKEVDPLHIQVIDLSSLGRGLTVQVLEREGREEWRKPMEVNRSLPGDGDGVGDEELQESVRGFLDALERSVRLRVEHIPRINRQEEGQSRVAVLFSGGVDCTLLAALVHRCLPIEESIDLLNVAFENPRKLLAEQAGKKKYKSAGVTTPGEADRPLPGGEETDKYTVPDRLTGLDAWSELRSICPGRTWNLVAIDVPCSDCIANEPLVRELMYPSETVMDLSLGNALFWAARGRGKLVVPADAGMEGDAKGRGGEEYESPARVLLSGLGADEQLAGYARHRRAFERLGWAGLVEELQTDISRLPTRNLGRDDRVISYLGKEVRYPYLSLDFVAFLSRLPVEWKVRLDGEGGDKWVLREAAERLGLKRAAGRKKRAMQFGSRSARMDQNAKKGYIKLDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQC7</accession>
    <name>M5FQC7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_119716</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623792.1">
        <property type="nucleotide sequence ID" value="XM_040770847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQC7"/>
    <dbReference type="STRING" id="1858805.M5FQC7"/>
    <dbReference type="GeneID" id="63685909"/>
    <dbReference type="HOGENOM" id="CLU_031312_1_0_1"/>
    <dbReference type="OMA" id="IIYEPIR"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="170"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT96894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="36977" checksum="592FDA7DAE62D04D" modified="2013-05-29" version="1">MFPPPSRPPFPSHSAPIDQDTATRSTDTDALHARLSASRLSYFPDPFVESFVLRAQGVPNRPALINVGTWLRGRSVDALVKGFVQRVGEGGKVQVLSLGAGSDTRFWRISSTPMGGKIARWVEVDFPEVTSSKARAIWKHAQLKGALGVCALTGGGTGVRGEKYALLPADLRLSPEKTLGALLTPANDTDALLSPTLPTLVLLECVLPYLPLREGETVLRWAGERFGKVAVVLYEMFGLGDAFGKVMRENLAVRGVQIPGTVASLDALNERFQRAGFEGQALTLRDIRTHYVPPAENERVAKLELMDEYEELDLVLGHYAVAWGSKGVTGWGMSRAEEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQZ8</accession>
    <name>M5FQZ8_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624132.1">
        <property type="nucleotide sequence ID" value="XM_040769361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQZ8"/>
    <dbReference type="GeneID" id="63684423"/>
    <dbReference type="HOGENOM" id="CLU_148790_0_0_1"/>
    <dbReference type="OrthoDB" id="3257409at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="17361" checksum="F07526573C13A68B" modified="2013-05-29" version="1">MSLPAEEPRLGQEELEPELQQQHQEEEEEEEKEEEEEDWEQEWQMHDSEGEGEGETSGIEELDEEIDLKSRMIADNLLAEDEKILTTFYTKMNGHCTNVQYNTLNFTYPNIIIYQSFLSFKLNMLMWKEQLPFLHIEPGKIPTHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR78</accession>
    <name>M5FR78_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626488.1">
        <property type="nucleotide sequence ID" value="XM_040773340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR78"/>
    <dbReference type="GeneID" id="63688402"/>
    <dbReference type="HOGENOM" id="CLU_1906666_0_0_1"/>
    <dbReference type="OrthoDB" id="2973896at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="15004" checksum="52B3FAE9756D5808" modified="2013-05-29" version="1">METELHDIDSTLWGFLDVCPNIIILRIVPCRSYTVVFQTQGTIYRDRDVSMPLVLVHNIANRLGGSLRELETSVNVDIESTAFLALLKGLHGLQVFLCPAVFGSKIKQIKQIGTTRKIFYRVMSCCLIFIPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRN5</accession>
    <name>M5FRN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626748.1">
        <property type="nucleotide sequence ID" value="XM_040777313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRN5"/>
    <dbReference type="STRING" id="1858805.M5FRN5"/>
    <dbReference type="GeneID" id="63692375"/>
    <dbReference type="HOGENOM" id="CLU_888496_0_0_1"/>
    <dbReference type="OrthoDB" id="2564234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="316" mass="32153" checksum="1AEEB8F7AF3AF7BB" modified="2013-05-29" version="1">MSYQMTINDTSPLVQYTGGWNQCFTVSGCTASAAGASGVGESYHAVNGSGVLQLTFSGDSIQVFGEFGDAAAGTISVDGSALATSYSASSAEGLDTLLASAQNLSSSQHTLQLQPSGPLNFTSAVVSVSSPSFQAVQPTSLPYWDPSITYSGTWTYPTVQGLPNGTARTNELGAQARLGFNGVGVVVYSSLNNGHGPFNVTLDGQTTEYTAAGEQWLVPETIVYYASHLQEGSHELVLSNNGAGGSTTFTLNSITVYQLAGSGPATGGNSTTTAPTTASTTPAPAGNGGNGSTCDRRSGRPGIPHPRCVLLPPTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRX3</accession>
    <name>M5FRX3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT97824.1"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="9576" checksum="693A3ACB50BFD67A" modified="2013-05-29" version="1">MEIIDREDPEVEGMANPPEEDKMWVRLAEHTLLMGNNLHVLLENALHALDVEEVEEGNEADEEDWETTREDACQGTSSLLNQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRY1</accession>
    <name>M5FRY1_DACPD</name>
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        <recommendedName>
            <fullName evidence="11">WAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_71506</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="1858805.M5FRY1"/>
    <dbReference type="GeneID" id="63691009"/>
    <dbReference type="HOGENOM" id="CLU_002631_1_1_1"/>
    <dbReference type="OMA" id="FVEVHCA"/>
    <dbReference type="OrthoDB" id="332390at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DDT_dom"/>
    </dbReference>
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        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075:SF6">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAC" evidence="8">
        <location>
            <begin position="62"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="7">
        <location>
            <begin position="541"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="685"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="808"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="897"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="776"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="946"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="701"/>
            <end position="733"/>
        </location>
    </feature>
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        <location>
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            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="829"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1152" mass="129511" checksum="80240A28EFDA784F" modified="2013-05-29" version="1">MPILRRKKVLFIPPPLMTGPPSPTSLSFGSLLHAGSPVADVKIEGEAEEAGKKSVLTLSPSTPVWYMKETGEIFTTYDAYCSRRAFYLQPIFQCEVTGKSGLRFFDALRSERAEARLLESRFPEQLKASVLRSVQFQVVGRLDGLVDRVYERFKDRFWTGERVIVDIAGERFIATICQVFPPRRRTSSNSSNTAVREPAPIHPFPTSLDSPPIDDAQAYFYSVQIVGGASATGLEKDGKEGTPAKREDKREDKPREGKRKSEANGEPEGNRRRSLRQRRQEEERDRLEKKSAPSSSAPPPPATGAVAVGSMKVEEPAVGEGFKGSLMEVTSSQLSRDRLTFSKSILRRYLAATVERGAALASPWEVKPSLCKRYGIDAHMPEARKEEVEVIRTQALGKRKKAVSEKMEERQREKREEKEREEKEREERERRERGEEVDEEEGRLKKRRKSGKKGEEKAEKKAAAEAEKRRKEEEERKRKEEEEAARKAAEEAAAAAAAKKKPVKYPTEDLDVRVNEREKKHGKPLRRPVWKKDVFFVDLGQEVWETFLETWNFLSIFSKPLLLAPFTMDDYAGALRHRLADPPCVLIAETHQALLTLIARDVPGKRHTALISLGVDVPDQLVELLNQTGESWQAGGWERKGRMGWEEALIGCLKEHATKTALPRLQLILEHLLLEDGAIKANGVGNGRTNDGGDLVERVEPTVGTSGTSTTEPPSSPITEISIEGSEETTTTPASPKTRYPTLPIADKLAILRFLTDLAVVSKAVKSFLEAGDGALTELRKEKIELNRERKRVAEELAVLEEKINPPKSEAEIKQAENGEAAAAPEDAESSKPNKGKKADSKIPKADSADTPLGSEEADQLDMDVSPSKSKKSNVRSKLAETPVDSDVDMDVEAFDMEPSSDAGSDTGSPVPANIDRHTSRQKSLLKKHLQREAEEALAAHRRSAARTATAVLRLLHNDKRKLEEEDVRYIKRLEAIEKEFRKLLAAQRQKPLGKDRFHNVIWWFDGMGGMNLTGAGGNFLWQTARVFIQGASEPDRRFWETTENFDERVKEEECETGLLGPGEWAYYDTPEDVEDFIMWLNLKGRREFNLERQIHNWGEFIVGGMRRRANELAASVGRALDTRRSSRVKTGMLEIMREPYMQYTNKKSAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS46</accession>
    <name>M5FS46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_18458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624852.1">
        <property type="nucleotide sequence ID" value="XM_040771361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS46"/>
    <dbReference type="GeneID" id="63686423"/>
    <dbReference type="HOGENOM" id="CLU_141768_0_0_1"/>
    <dbReference type="OrthoDB" id="3349961at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="14446" checksum="7B68F58F77F8EF34" modified="2013-05-29" version="1">MHRFGNDDTWSIVDRAEVRPVWTIDEDAVFDDIHTGHEIVGRYTFDMKGGFQQRKALRHARGQMIKTAKEMGWNVFIREGWSVTSLRRGENDFRLEVVYRARPAQSECLSSAKEPPFLTYLPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSA5</accession>
    <name>M5FSA5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_70529</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fungal Na(+)/H(+) exchanger family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT98683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625581.1">
        <property type="nucleotide sequence ID" value="XM_040775922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSA5"/>
    <dbReference type="STRING" id="1858805.M5FSA5"/>
    <dbReference type="GeneID" id="63690984"/>
    <dbReference type="HOGENOM" id="CLU_290701_0_0_1"/>
    <dbReference type="OrthoDB" id="2190219at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF4">
        <property type="entry name" value="NA(+)_H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
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        <location>
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            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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            <end position="439"/>
        </location>
    </feature>
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            <begin position="28"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        <location>
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
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            <end position="908"/>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
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        <location>
            <begin position="1012"/>
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    </evidence>
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        </source>
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT95</accession>
    <name>M5FT95_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="Stenlid J."/>
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                <person name="Syed K."/>
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                <person name="Young D."/>
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                <person name="Eastwood D.C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="72" mass="8284" checksum="47E7FF448B3C3735" modified="2013-05-29" version="1">MPFRIGKAWRADICAFDHVNESRRLHPYYGQSGLLRREIPEALRLSISARPNVNTTLKGFMGKMVAIWVPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTI3</accession>
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        <submittedName>
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        </submittedName>
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    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110121</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626296.1">
        <property type="nucleotide sequence ID" value="XM_040769000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTI3"/>
    <dbReference type="GeneID" id="63684062"/>
    <dbReference type="HOGENOM" id="CLU_624952_0_0_1"/>
    <dbReference type="OrthoDB" id="3174109at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="439" mass="46536" checksum="14BB81662148370F" modified="2013-05-29" version="1" fragment="single">MSIPLAQRCTTLYELYGGTFVRGTSQPLLALHPHPPQQAQHAEDQPRRTDGIYVVDLPSEVGELESASWERPLNLPLGAGGGGTVEDFTLDRAGDLWVGVGRVGEEYVIHLRTLSTGGEHPLARVGEIRHRRGRGYAPAPADADGDEDADADGNADGNGNAGEGNEDGNADAGEGNANADGNGNPEARTSYTMQLCGTSLGILFHYPPQPHPQPHPHPHPHAEPHPDPQPSQELLIWNWTTSTLRAQLTPADADLGEEEEMHSFSFLAEDVVMLAKTGVGEAGLEVVWVPEAAAGSGSAPSPGEGQPTARASAKATASARARARQWKPREAQKICTFRLPKLRREWTYTSIVTRSDPAPVARPFDTLPMPSGSDSGSDFVSGSGSGFGFASGSAAHFRSRSDSQSQSQSQSRYTPTSPGRSRAPPPLTPLTTPPPPSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTJ2</accession>
    <name>M5FTJ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627863.1">
        <property type="nucleotide sequence ID" value="XM_040772956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTJ2"/>
    <dbReference type="STRING" id="1858805.M5FTJ2"/>
    <dbReference type="GeneID" id="63688018"/>
    <dbReference type="HOGENOM" id="CLU_065417_0_0_1"/>
    <dbReference type="OMA" id="FFSIRPT"/>
    <dbReference type="OrthoDB" id="5581259at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29427" checksum="B0C6644F1D54DEB5" modified="2013-05-29" version="1">MPPPPPSPWPHYAWAAGHLLLLVCAIKYLVSIFTFKAASNVIWYKLSYAGALISYAIVCFKAVGMPQASPQYAQRALADENVQYFLLSLYWFLTRPIFPSLIPFATFSAFHTLTFVRTNIIPKILPSKPPPPAQPGQPAPRAEQHPYAKAIGTWVRNNYESAMQIVAFAELVIFAYVSVGALIRRNSLLTPVIYAHFLRQRYMFSSFTRQAVNAFTAAADARINAPGSPPWLQQGWVAIKLAGARWAAAIPGGTPAAQPQQERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU38</accession>
    <name>M5FU38_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDP-fucose protein O-fucosyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_101597</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 68 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625907.1">
        <property type="nucleotide sequence ID" value="XM_040767571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU38"/>
    <dbReference type="STRING" id="1858805.M5FU38"/>
    <dbReference type="GeneID" id="63682633"/>
    <dbReference type="HOGENOM" id="CLU_032339_0_0_1"/>
    <dbReference type="OMA" id="GLRVKYW"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="506" mass="56898" checksum="FE95FD381C3D8AB4" modified="2013-05-29" version="1">MASKHVPKPSWTGGPPLSSQAPPYAQFSPSPSSPESRSSSPPPFLLPLRLPFTRSYLRKRRTPLPAVLAGLTILTLSVLLFLVMSRRCEPVQVVQQVGVRQGVDDRFATRNWVRGPPKPRFADNLKPDVKYISTFVSSGWTANDVMTYGNLLYLSLLTQRVPVLGPFVPSHLSSTAGYIPFSDVFDIAHLAKSMNAPVLEWGDLKSVEEGVEEELGCWSAWMATSREIKDPRWSWIPGVFGLDISYTPLPYDHKMFPEQDNEPHLKYGKLMQLSFPSERARALSLSSPRGTKSGNPLLPSDHLLCFDQMYAISLEQQWEWFVDSSPVWRFVGRHMRWNKNAEALAKNYLAKHWGVPQGGLLPPYISVHARRGDFTAHCQWMHQTGSSCLPSLTQLQRRVSEVSEKLALKGVHTDRVLVTSDEKDETWWAGVGQLGYTWVDHKALRTDELYGEWYSPLLDAIFHSLAAGFVGTDQSTMSLLAARRVEEWNDGPVGFLLWQGVPEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU60</accession>
    <name>M5FU60_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal membrane protein PEX13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_67073</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628123.1">
        <property type="nucleotide sequence ID" value="XM_040775836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU60"/>
    <dbReference type="STRING" id="1858805.M5FU60"/>
    <dbReference type="GeneID" id="63690898"/>
    <dbReference type="HOGENOM" id="CLU_034386_1_2_1"/>
    <dbReference type="OMA" id="EGWFPKK"/>
    <dbReference type="OrthoDB" id="10037838at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11771">
        <property type="entry name" value="SH3_Pex13p_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007223">
        <property type="entry name" value="Peroxin-13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04088">
        <property type="entry name" value="Peroxin-13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="295"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU01226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="373" mass="40478" checksum="CA338D17595AAF1E" modified="2013-05-29" version="1">MAAPPKPWERQTQVSAAAAAPTVTATAPSMPAETRPSVDSAPSLPTRPSSITNPLPTVAGSSALAQPFVSSYSQPYSAYGNTFGAPYSSPYSSFGSPYSRFGSYGGYGGYGGGYGGYSSPYNPLMPGQPGYDPNNPSLTQRMEASTSQTFQLLSSLVQTFGSFAQMLESTYMATHSSFFAMIGVADQFATLRKYLGEVLGVFSLLAWLRGWWRGERTATSLSRDFHAFLQGAKGPDGRPLPRPSRKPLIIFLLAAFGLPYMMHKLINLLSKRQPLPPIADPQNALANGQEILDPSSLTFARSLYPFDTTDPVELPLKKNEIVAVLSKLDPVTGVEGEWWRGRTRDGRTGWFPRKWVEIIKKGTDEPATPKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUC9</accession>
    <name>M5FUC9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RTA1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628228.1">
        <property type="nucleotide sequence ID" value="XM_040772836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUC9"/>
    <dbReference type="GeneID" id="63687898"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_1_1"/>
    <dbReference type="OMA" id="FIWSNEV"/>
    <dbReference type="OrthoDB" id="3357408at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="37858" checksum="39B450532B920341" modified="2013-05-29" version="1">MADFPIDYAYLVGSWCSAVLWGVYGVLFGLCLWLVFNHGQLHPVQLAALISLYVLATCHITLDFVRLIQGFVFTDSGLPRIYFFSNVALKINVAKDFLYITSLIIGDSVIVWRCWIVWRKKWVVVAFPILMVVGEAIAGYVAIGKYLSPDLTTDTSIKPWGTAMFSISLATNILVTSLTAGRIWWISRTTNKLMAGTGAGTRSLAAITLIIESGLAITLAKIIEFATFQIAFAGTVNMQAIYIMFELMPQLFGIVPTVIILSIQVGVTSSKAYSAGNGPHSLPRNGVFGANSGEAHVTSYGRRTPGAFPIVSVETTTYGDHHASEIELGAKTATMPKLDRKASTDSSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV49</accession>
    <name>M5FV49_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_89314</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628543.1">
        <property type="nucleotide sequence ID" value="XM_040776906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV49"/>
    <dbReference type="STRING" id="1858805.M5FV49"/>
    <dbReference type="GeneID" id="63691968"/>
    <dbReference type="HOGENOM" id="CLU_030988_10_2_1"/>
    <dbReference type="OMA" id="DHKSQYI"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000007">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0749">Sporulation</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 19" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="20">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="18">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU01646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="158" mass="17873" checksum="39FDFCF67DFAC289" modified="2013-05-29" version="1">MSTACRRRLIRDFKRLSTDPPSGVSGSPCPDNIMVWNAVIFGPSDTPFEDGTFKLTLTFDESYPNKPPTVKFLSRMFHPNVYATGELCLDILQNRWSPTYDVAAILTSVQSLLHDPNPNSPANAEAAQLYRENMKEYVRRVKTTVEESWMDGVVEQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV60</accession>
    <name>M5FV60_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Delta 8-(E)-sphingolipid desaturase</fullName>
            <ecNumber evidence="5">1.14.19.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_117730</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.18" evidence="5"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626387.1">
        <property type="nucleotide sequence ID" value="XM_040770442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV60"/>
    <dbReference type="STRING" id="1858805.M5FV60"/>
    <dbReference type="GeneID" id="63685504"/>
    <dbReference type="HOGENOM" id="CLU_016265_3_1_1"/>
    <dbReference type="OMA" id="LYNCNYF"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF30">
        <property type="entry name" value="DELTA 8-(E)-SPHINGOLIPID DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="17">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT99489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="514" mass="58358" checksum="715EE7483458E921" modified="2013-05-29" version="1">MASPNHRLWTRTQVAQAIKSGQTLVIYNGNLLRIPDSWLAQHPGGRLAIQHYIGRDATGEIDGFHSPYTLASRLKNYVVGRVDYGEEGWTPLLPPLETGWVRKPAPGGKWSWVNEAARLPSGGESEFLLIKKADMVDDAGPPLDALEPRPTSLLQKAQHTHALALRELHEEIKKQGLYKCRYLTGYGPEMLRYTLFAVLSIWLFRTERYLLSAVVLGILWHQLTFVAHDLGHCGVTGDWFKDRVLGIIIADLLGGLSIGWWVDNHNIHHLVTNHPTHDPDIQHLPFFAITPRFFNSLWSTYYNRIMSFDLPSRILIRIQPYTYYPILSLARFNLYANSYLFLLGDRGRYRLAELGCIVLFWTWFSAILSLIPSPRTRLLFFLITQIVPSPVHVQIVQSHFARSTADLGPWESFPDRQLRTTTDVSCPSSMEWVHGGLQLQVTHHLFPRLPRHNLKAASKLVKLYAQEQGLEYAEFGFVETNGQVLGVLREVANQVEVFCKVAKAEAEGNLSQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVD8</accession>
    <name>M5FVD8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624189.1">
        <property type="nucleotide sequence ID" value="XM_040769295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVD8"/>
    <dbReference type="GeneID" id="63684357"/>
    <dbReference type="HOGENOM" id="CLU_3055925_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="55" mass="6066" checksum="EA20F33405D7106B" modified="2013-05-29" version="1" fragment="single">MSYYGGYMPYYPSYNTYPTYAATYGTYGTYGMNGMNGMGAMGAMGYPYYGNYGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVK7</accession>
    <name>M5FVK7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626542.1">
        <property type="nucleotide sequence ID" value="XM_040773357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVK7"/>
    <dbReference type="STRING" id="1858805.M5FVK7"/>
    <dbReference type="GeneID" id="63688419"/>
    <dbReference type="HOGENOM" id="CLU_1686509_0_0_1"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="25"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="17225" checksum="EA7F0F9F02103A88" modified="2013-05-29" version="1">MPEEVGPVVEHKDAEGRGPLGRKWKAHLCFCTDCRLSLGHLLPSFISVDNDYITWLEKGTLKTYDSSPEKGTQRLFCGKCGASVGKRLPGRSELDVNLGMLELEGEGEEGGKGEGLAGVLREWTVWEKPRFMAEAGDGRLRDEILSGMKRDGFILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVR1</accession>
    <name>M5FVR1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature requirement protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
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                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
                <person name="Hesse C."/>
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                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Ohm R.A."/>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="279" mass="30107" checksum="DEB6EA367FD8C243" modified="2013-05-29" version="1">MHTAYSHFIPCTKLVHQTLEAQKAETPPSAHSSPTPATPEAQEGERDRLHQEKQAADSAAAKARALHKHARELHRATVQIHGYGPAAAETKKNQEEKQFQLYGAFDSEYSGAVGAQRAAADRLDASLSQDREVKAPPLPPKRRNSTPGVTKTSPPPKKRRNSDPGQRKDGNTHPLQLFTPVTTPRGSRPATPAPQSHSNAGARHQESNPDILSPQELAPTVHPERVSSPQSQNGKTPSPSLTPSPPTAPQPKKWNSMVAGAVKQLVPKVPAPKRNNTAK</sequence>
</entry>
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                <person name="Blanchette R.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="9">
        <location>
            <begin position="9"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="348"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="416"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="598" mass="67813" checksum="C28F0D25262592EE" modified="2013-05-29" version="1">MAALDVRQVVAELRQAVDDCGDRGLTTAADWASELLNAIPYSVRRYVPLRQHSPNEAGPSYPLRASTSTPIRSSNANLSAESAMEVTEDDVVPPSLDEEDDQDRIRRAQGLLGKREIRRAAEVLKGCKSGLGRFLRLYARYLMSDKYADERWNADQHNRAKWTPSPVNDQLNELINDIGSPTEPFLLFLKGILLFRAKKRAEAMEALLLSLRSYPCNWSCWIQLGHCIDSVEEFTRLQPLLPSHFTTRIFTVKMAADLYTASLDNTVETIDTLLETFPSSSFLKAQKALVFFNIQSEEAERIFDEIQETDPDRVDDMDVYSNVLYVLDKPTKLGDVARRMIKVNKDRPEVCCLVGNYHSMRGDHEKAVLYFRRALTLDKSYIAAWTLVGHEYLEMKNPQAAIEAYRRAVDVNRKDYRAWYGLGQTYELLDMFSYALHYYQRAAAIRPYDSRMWQALATCYTAMKRPLDALECLKRALMGEDADQIQLYTRIANLLDYNGDHAVATTYHRKIVAACTTANRPIADYAKSLLALAQSIADSESPEGIHEAMEWMEQVRESSCEEAGVAGDMYRKLDSLASGYAMQARGEGQQQVQSAQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWQ9</accession>
    <name>M5FWQ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_54312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627731.1">
        <property type="nucleotide sequence ID" value="XM_040775242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWQ9"/>
    <dbReference type="GeneID" id="63690304"/>
    <dbReference type="HOGENOM" id="CLU_000960_26_0_1"/>
    <dbReference type="OMA" id="HGLAYFP"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF39">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="28"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="542" mass="58478" checksum="FDF502952505746E" modified="2013-05-29" version="1">MTKEKVALAPDEQPVPTKKERRLRIIKLAVSLMLPVFLETLDQTVVATAQTRIASQFNSLGEQQWIGTAYLLTATVFLPIFGSIADIFGRYWALQLATLLFIIGSAICTGAQNMIPLIIGRALSGIGAGGLTTLARIILNDSGNLKDNNTQTAILSLLYAIGYAVGPVIGGGLATANWRWCFAINLPCCVLGMLASYFFLRHHPNPAAPPPGTTAIQKLQKIDYVGAFLFVSGGVLIILGLSWGSQEEWNEPRVIAVFVVGGVLVILFYLWERFLERRVAGPHKEVAWLAEQPMIPAALFKDLDVIATSVIIFGGGMLMFGMFYFVSTYFIIVQGYSQIRAGLVLLAFTPGLGVGVMISRRVILVTKQAKYVCVVGAFLAPIGAGLTGMAMQNGNTTELYVFTAIVGLSCGLVIPSTAIQLRFTHQSDEVATVVALSMFFRTMGGTVGLAQMGAVLNAKARDSLLAAAYLGQYTAQEIGEAIAALVSQDLIQGLPEHVLNLVRSSMSNGVYWSFISLIPWVGVGALISLFMSRHLMFEEPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWR8</accession>
    <name>M5FWR8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629295.1">
        <property type="nucleotide sequence ID" value="XM_040775067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWR8"/>
    <dbReference type="STRING" id="1858805.M5FWR8"/>
    <dbReference type="GeneID" id="63690129"/>
    <dbReference type="HOGENOM" id="CLU_2291596_0_0_1"/>
    <dbReference type="OrthoDB" id="2986975at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11690" checksum="42D520EEC74D2CDA" modified="2013-05-29" version="1">MIPVKAKSNHHLSTDKLAEIWREVHYLIIDEISMVSKSFLARISSHITTACMATDPNAPIDLPLGRLNIGHQIYKHFSMVMILKEQCQIEDPIWMCFLWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWU7</accession>
    <name>M5FWU7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator MFS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_79252</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629340.1">
        <property type="nucleotide sequence ID" value="XM_040776388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWU7"/>
    <dbReference type="GeneID" id="63691450"/>
    <dbReference type="HOGENOM" id="CLU_008983_0_0_1"/>
    <dbReference type="OMA" id="NVDNEDP"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF17">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="659"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="686"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="731"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="760"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="253"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="330"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="785" mass="84834" checksum="CC9F3B25F07C3D72" modified="2013-05-29" version="1">MSGRRRISDARKFARDEEIQQLIDAEPDLPPPVPTVRKDASSAPLPILPMLVLAIAMLGEFLSANVSTPFLLFMVESFGVADDEAQVGYLTGVLASMFFITQFFTSLLWSTVANRHGARAVLFVSLLGNAITCVIFGTSRSYSEAIVIRLTQGVFNGAVGVARGTVATITTPDNEGRAYAILGFCWGMGGVTGAILGGSLESPALKFGGRFDTPFWHSYPYLLPAAIASCVTLTGAFLSLFLAWDGGPRNGAIRLPEKNPDEAEHEPAPNLPTMHEEDEESAIGVEPAPVPAPEEMQPEPPEQPNTIVTQLQNRVTKRLSGYFARRVREHQTLASSPGNTPPSNGPRQIHRSVSGPVPRARAGSAYGYGSRNLPSGLNGLRSRHASIQTIRRRRSSVYGGDDAYTDDQPTQNLSLAQRLLMANEFTVTSMGDLWVAAALNTEAEQVVDDTPVASDNEEENVNADAPESMLTTGQTSPNRRRFSQANLRAPEPSNGVTFSRFSTFQSFTSSDSPRENRRLSFASTLPPIMNNTGLAEPPGVLLSSREMTVESGLEPIVEGHVSHEEQQSQSVEIAPSSNLWSSLPLVIIFQYGLLALHSTTHDQVFYSYLVSQYKSGGLGLNPAGFAQLIALMSIAQMIFQFLLYPSVGPPRGRFSHLAMFRIGSLLFIPAYLSVIPYRLFTNAEGGGYVIVMIGLAISTATRYCGSTFCYTAVAILLNYMSPPPVVGLANGLAQSVVSLSRFIGPILGGYIWSVSVQDHASGYTFGFFIVSMICGLAILHSMTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX61</accession>
    <name>M5FX61_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_99675</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629465.1">
        <property type="nucleotide sequence ID" value="XM_040777611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX61"/>
    <dbReference type="STRING" id="1858805.M5FX61"/>
    <dbReference type="GeneID" id="63692673"/>
    <dbReference type="HOGENOM" id="CLU_022941_0_0_1"/>
    <dbReference type="OrthoDB" id="6017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="97"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="264"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="186"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="502"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="688" mass="75513" checksum="6E2BDECD256D6719" modified="2013-05-29" version="1">MSSSPIIPEITIEQPVKPRKPRMGIDPANIIDGPRLKKRKESPDPSAGGKHKQGRPSEEKRRSIKQEEADVGTEQRVKVAEDGSGVWKTVREEKDSTGRLLCYDFLRLPSRRLYPDYYEIIKRPLCMEDVKMSLDSLSYSNLEAVRQDLLTIFRNAQRYNVKESTIWQDAKHMKKLINKQFKALNHHSHDDDDDDDEHAGQAKPIHEQAELDVDGVDIGVDGEDAHDGHEAETGVKSRKRRPPTMQKALRFRLQKLTKKTDEEANRDRCGIFMELPSRKDWPHYYELIKQPMCLSQILEKVNKNEYTSAAECTADVDLMFSNALTFNEEGSTIAEDAKFLRQAWHDSLKTLPTRISDQPSSNGDASLTKIRIKRPLEPVLGTSSLVNIDVGSPAKMVSPVLVSRSPGLSHTSPILPAARVSEGQSRAASEAASSPLLAGPAQYQAPTPVPGMARQFPSANPLAAYYSTLYPSPAGRSSPYMSPPTGGSQSGASTATALIPTGVSSAGSEQNPPTGNGTSTPASVPTAAPMAKSPPPPEDPKRRIIKQIDLVIQPSNRTVALKDDIAKAYSLILGLSESKMLIGLEFNPIYTEENATEGSSTDDVQISSPVDNNSLSHHFTCTVRVNGKVVETMPTDELVVNGNADLGRESPAWLVELTSGMNVVDIIAEPRESQGKAQVWKLFVMKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXL0</accession>
    <name>M5FXL0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_83977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625129.1">
        <property type="nucleotide sequence ID" value="XM_040776655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXL0"/>
    <dbReference type="STRING" id="1858805.M5FXL0"/>
    <dbReference type="GeneID" id="63691717"/>
    <dbReference type="HOGENOM" id="CLU_017445_0_0_1"/>
    <dbReference type="OMA" id="EWAGRAY"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051831">
        <property type="entry name" value="Bromodomain_contain_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881:SF27">
        <property type="entry name" value="BROMODOMAIN CONTAINING 7_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881">
        <property type="entry name" value="BROMODOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="434"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="622"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="704" mass="77553" checksum="B49079A746011210" modified="2013-05-29" version="1">MDLGTMGQKVDKGRYRSIDEFREDFLLVTTNAKTFNPPSTIFHSEAAKLEKYGLDAINKAQQKLTEAELQAQALAETQAASAVAAQAEYELRHQDDLIKVESDGEGEDGMRAESMERGSRSVSAAPTPGGGATQMRLGKRRGGYRPRGAPKSLDELWKIPGPETGIGAFPRGSDFAGLMLEFEIMGRKTLTKKERIKLERHPLKRPIAPDGSIDYAEMEDPFSFLSVFLPERFGLPELDLVPAASTGNLPKQKYETPAYPSVYAPVSVPPTIISMRTAAENAPVEDEGVHWTVQRPGMNSYRSYVAREEEEMRKQAERDSQAKELEARDPAPTDWGSFGTLPMKWSIGDNTWYSDESKLHMKIREDIRKAAERLRTGKRKADAKPSDERQKELEKAAFGGEAWLRDVVYGGPEGIAYVQSVASFVDKAMKYAQEGNEETTGDSRVKIEEDIDMDDAQERPSKRRRIEQVDESVVLPTPLPEYVSDLVIDPLTSGLHEILDRIGEAIEDPDLPLPRHLPQLGKHLENSVNLVPEAEGRLSELNSVVGDQLDMGAVLRAPDEFFYKDDEWTERSKKAPAAEETNTSTPIAAANGATLSPASPAYINYGLAKAAESILRLSQAVHPAPSTSSTQTSDGTAVDAVAGSEDGEKVDNASDEDPEMRKLRLNLLTMTRHVPLAELAPLKPELIPGHVRHLFPARIGGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXV8</accession>
    <name>M5FXV8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein 188</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_118662</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNEP1R1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625274.1">
        <property type="nucleotide sequence ID" value="XM_040770635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXV8"/>
    <dbReference type="STRING" id="1858805.M5FXV8"/>
    <dbReference type="GeneID" id="63685697"/>
    <dbReference type="HOGENOM" id="CLU_041822_0_0_1"/>
    <dbReference type="OMA" id="NMYLNMR"/>
    <dbReference type="OrthoDB" id="5599171at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071595">
        <property type="term" value="C:Nem1-Spo7 phosphatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019168">
        <property type="entry name" value="NEP1-R1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005605">
        <property type="entry name" value="Spo7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20996">
        <property type="entry name" value="NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20996:SF1">
        <property type="entry name" value="NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03907">
        <property type="entry name" value="Spo7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="239"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="36674" checksum="67D2E82A8A78B1C3" modified="2013-05-29" version="1">MPPRAKPASYYPPADHATFKDLLRFEERLKTNNARLKKQKARYQFFLLVLLIYISLLTSDVLFNTFFTSYPINFALKAEHPLWEPIWIPHPYVTPGLLLIACTTLVLFFASGTYAEKIGYANRYVPSANRALRSFNLYFNIRSPSIFPYPLSLLFQSPPHPPHPPTQSAPSPPHHASRSALQPLPPASNPRGELIFSARVSPTFKDAYEAHRAGFERMRAKKRQPNKWWALSWVSGTGAGAGKEAEHEEHEGEKRGERRRSVSLESSLAPTPNSSRLPSRSPSPVMDVANDGELRPDTERVPGMIPVRRRSARIASKLEGLEKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYG7</accession>
    <name>M5FYG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_85786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623460.1">
        <property type="nucleotide sequence ID" value="XM_040776746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYG7"/>
    <dbReference type="STRING" id="1858805.M5FYG7"/>
    <dbReference type="GeneID" id="63691808"/>
    <dbReference type="HOGENOM" id="CLU_009938_1_1_1"/>
    <dbReference type="OMA" id="DGCVNKK"/>
    <dbReference type="OrthoDB" id="6275295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="34"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="4">
        <location>
            <begin position="529"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="218"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="70870" checksum="D6723C08F601DFE6" modified="2013-05-29" version="1">MLGGLNRLGLGLRAPPPSYASHGIASAQSSDKLTTLFVGSISAGIDNAFLEQLFTVCACHLTDRPSCGTLRSFKRLLNAQNKPQAFGFAEYEEPEAVDRALQTLNGLQLPNLEDPNGEAKKLLVKADDKTKAYLAAYEAQRMRTESDEEALISARASISHLVSTIAQAGMSSSNMPNKKDAPIPPHLRDLQEADLPEEQRGLVMSEIAMFRDRAAKKEVEKRKQAEEAAQSASAAAIAMSPIGPPTGPGRGWGRGQPPPSGPHQGFGTGPQSYNRPVGFVRGGDVGWQQRRPSHGGASESDLRSPSSIEKSDWELEQERLEMRRQQEETSFRDRERRYENRERTRITQIERQIARDTALESQRERDRADMSVRLEMWDDDESDELFYTDRAAWRSKRAQSLARERTADQRSWEIEQREAEHLRLESEKFLERQMEDLALMMDEQRKAGLLLDDIAPLKLSINAAVPKIEEKRETKPEPKKLMMEEEDEEDTSKKRSGLVKLDFDAMSRGGKRVEKLETLKGRVLAMDTDEVIKTKLNWLALNDATIDAKVEPLARRKITGYLGELDDDELVMFAVEHVKDRKGPTELAEGLEPVLEEEAKDFVNDLWRQLVFESMAYAEGVDTMDMFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZG9</accession>
    <name>M5FZG9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623795.1">
        <property type="nucleotide sequence ID" value="XM_040769379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZG9"/>
    <dbReference type="STRING" id="1858805.M5FZG9"/>
    <dbReference type="GeneID" id="63684441"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="SDEPQFN"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="35429" checksum="E8C3A75AA1AB5812" modified="2013-05-29" version="1">MTIVNPPAKVLVTGANGYIAVWICRILLEKGYSVRGTVRTPSKGDYLKKLFEKEGERFEYVLVEDITAEGAFDEAVKGVQGVLHTASPVAMAIKHPDELIKPAVQGTLSVLTSVDKYGTEVGRVVITSSCAAILEPHEGGYVYTEKDWNDFSLHEVEQKSEKAAPIHQYRTSKTLAEQNAWRFEKEKTGKWDLVTILPPYVFGPLLQETAGKDSLNFSAQLIYDAVVTPKTGEALYSYAGKLEEAGGERIIVSAGYFAWQDLYDALSSPSLDPPFPDAPKGSSERGAPLIYSGDLCNKLFGIGFRGLRESARDTVFSVRERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZK1</accession>
    <name>M5FZK1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_94993</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628207.1">
        <property type="nucleotide sequence ID" value="XM_040777257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZK1"/>
    <dbReference type="STRING" id="1858805.M5FZK1"/>
    <dbReference type="GeneID" id="63692319"/>
    <dbReference type="HOGENOM" id="CLU_000995_7_1_1"/>
    <dbReference type="OMA" id="AFFKCNV"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="493"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU01310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="913" mass="99932" checksum="162EC323C78ABCA9" modified="2013-05-29" version="1">MTSSPLAFASSSPGRTPRGSQMPTSSAEPLFFPPSSPAAQGSGDQTPTQRRARRGDIHSVSSPHLLSQAQAHARASRVPATPATPAHEPSSQLYPPSSAAPEPHLSNAQTASSGFDDVTSVVWGTNVSIMEAMKTFSEFLREFKPKYRRAHDAARGIAHPPLAHPEDGEVPLYQTYLRKMRLTGQTNLNLDAENLLAWPSTRKLHSQLLKYPQEIIPVMDTALKDAMISLAAEDKENGMQGMEGDLGEEEIREIEGKVYKVRPFGIDAVNMRELNPSDTDKLVSIKGLVIRATPIIPDMKQAFFRCLICSHTVQVEIDRGRIEEPSRCPRDVCQSLGTMSLIHNRSEFADRQIIRLQETPDKVPDGQTPHTVSLCVYDELVDLSKPGDRLTVTGIFRSIPVRVNPRQRVIKSLFKTYLDIVHVKRANAQRLGYDQSTRSEGRIPGAIGVGGEEADEAEHAAGSAAGAEAGVDGLSRTAEIEEKVLELSRRADIYDVLARSLAPSIWEMDDVKKGILLQLFGGTNKSITRGGGGGGPRYRGDINVLLVGDPGTSKSQILHYVHKIAPRGVYTSGKGSSAVGLTAYVTRDPDSKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTVSIAKAGIITTLNARTSILAAANPVGSRYNVKWPITKNIDLPPTLLSRFDLLYLVLDKVDEVADRRLAKHLVGLYLEDAPETGGTDIIPVELLTAYISYARSKIHPQITAAASEALVRAYVDLRKLGEDPRSGERRITATTRQLESMIRLSEAHARMRFSDQVEVEDVLEGNRLMQEALRTSATDPRTGLIDMELINTGVGEQQRRMQGDLRRAVLALLDSQAGGRGVRWTEAVRMLGQQSSVQVDQAEFAEVVRGLEVEGQVKVVGDRERRTIRRVASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZS3</accession>
    <name>M5FZS3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_16105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628287.1">
        <property type="nucleotide sequence ID" value="XM_040771164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZS3"/>
    <dbReference type="STRING" id="1858805.M5FZS3"/>
    <dbReference type="GeneID" id="63686226"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="303" mass="33194" checksum="E0D0C9CECECF44A4" modified="2013-05-29" version="1">MANKLVVVLGATGHQGGSVVTALLNHGGYSIRGLTRNTESLPAKDLAAKGVEMVQASLIDKSSLVAAFRGAYAKVYAITLPFTGVNEDVMGRNIVDACRANNVPLLVLSSLPSSLEVSNGKFNVQLMEEKCRVPAYASEVGQPTVVFYLGAFCENLLQHMGRSQLQPVSADRTKWQIFYPIVPASVPQPLSYISADVGPSALAVIDRWEDPAARERLTKAPIVVCSFMITGEEMEQTIARVTGKEVKYVPIQVPEPMKTMFDFCAEVWYPDELPPPVLKDLGVKFHTFEDYVREEVVPFMAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G044</accession>
    <name>M5G044_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_82264</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626074.1">
        <property type="nucleotide sequence ID" value="XM_040776559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G044"/>
    <dbReference type="STRING" id="1858805.M5G044"/>
    <dbReference type="GeneID" id="63691621"/>
    <dbReference type="HOGENOM" id="CLU_076902_7_2_1"/>
    <dbReference type="OMA" id="EQTVEYV"/>
    <dbReference type="OrthoDB" id="268799at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000044">
        <property type="entry name" value="Probable U6 snRNA-associated Sm-like protein LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 16" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10 16" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9 16" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="17">
        <location>
            <begin position="16"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT99176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="9434" checksum="A1D301D86A250844" modified="2013-05-29" version="1">MSSEPPQDSSTGAVGTPADFLKGVIGKRVVVRLISGVDYQGLLSCLDGYMNIALEQTEEYVDGAVVNRYGDAFIRGNNVLYISAMESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0A7</accession>
    <name>M5G0A7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624115.1">
        <property type="nucleotide sequence ID" value="XM_040769358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0A7"/>
    <dbReference type="GeneID" id="63684420"/>
    <dbReference type="HOGENOM" id="CLU_1069659_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067347" evidence="2">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="29008" checksum="4E7D4D74FB3AFA8B" modified="2013-05-29" version="1">MHARLALLVLSATVIFAHPIPAPSDIAHFDEGHVLDGALREELDDGRALVARGGDGKPSVWGSLGKKLRIANFWSEGPKTSYHQLPDSDSDTATQEKHEAEGERLKQEHQHALETHRMLRTKVVQATQKADVANKTNKRERTEQTRQAHEEAQQHLKTRKDAVQRNVGVVRKTNEAANRWEKKNAERNLEKASHTKKTGKDTLQALQDSLSTADGETRKRILKQIKEQKRVNAVNRNGKVVALRAYQVIGIPDAVAGLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0M1</accession>
    <name>M5G0M1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_59363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624245.1">
        <property type="nucleotide sequence ID" value="XM_040775556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0M1"/>
    <dbReference type="STRING" id="1858805.M5G0M1"/>
    <dbReference type="GeneID" id="63690618"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="36207" checksum="B2EEB8F0D801D3E3" modified="2013-05-29" version="1">MASNRIPDLPANTTLQGLSVLVTGSNQGLGYHAALLSLQLGASPVYLAVRNLKKGHEARTAMLADPVVRKKNSKAIVKVYELDMARWDSVKSFAEKFIGDRHAAGEGLDIAMLNAGLYHMRFELAPTGNELTVQVNHLSTALLSLLLLSILEASTIPKHTARLMIVSSGQHRQASSTLTECPSDDNYLTSLNDVKNFASMTRYGLSKMLVIFFLRVLATKVSSDRVIINNVCPGLIRTNLARELPVFLRPVLYLLFLGQANPVERGAACYIHGVTCVGKESHGLWYRRMVLTPYGDFLLSDEGKKMQDKIWTETLQQLEQVVPGVSSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1C6</accession>
    <name>M5G1C6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_114461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630930.1">
        <property type="nucleotide sequence ID" value="XM_040769826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1C6"/>
    <dbReference type="STRING" id="1858805.M5G1C6"/>
    <dbReference type="GeneID" id="63684888"/>
    <dbReference type="HOGENOM" id="CLU_365236_0_0_1"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="99"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="764" mass="85515" checksum="9E36237090061085" modified="2013-05-29" version="1">MSAPQQAESSSAGRKRSKWESLDEADEPTPRRVKIKRPKREAVESSPLPNSVSSLRAGTSTPPSRSPRLVTAADSSRSRYVPRRSLYPPIAPCRSVYTYERLNHIEEGSYGVVFRARDRDTGDIVALKKLKLDQEKGGFPITSLREVMALMTCRHKHVVPIREIVVGDTLTQIFIVMDFIEHDLKTLLTVMPTPFLQSEIKTLLLQLLSAVAHCHANWVLHRDLKTSNLLMNNRGQIKVADFGLARTFGDPLGKMTELVVTLWYRAPELLLGAKTYSTAIDVWSVGCIFGELLLNEPLFQAKGEIEMLSMISKLLGPPTEQTWPGVEDLPLASTINWPARTSSLRSRFPYITEAGLDLLDRFLTYDPEKRISAEEAMGHPYFSESPLPKHPDLFGSFPSIAAGENSVPFCTPTDRQLPNGIRFRLIVADPSIGRRRYTSLTRRADCSTSIRLTSPGVIGVQYQRRRAKFMGDVAGHVIGNGLMGCRRTSSFYIPTRAPVCRSTTSASVNQQEFPMAQYLAQHTTEACCQAVKHTGTPRGELIDVGGVQTYITYPPDKSTDRVIIFYCDVYGPHFLNNQLVMDFFAEHGYTVISPDYFNGEQLEKLREQPGFDTMAWAAPYRVSVPKFVVDKFLPAVKEKFTSVKAYASVGYCFGAPMVLNDLVAGRSEAGAVAHPSTLTEQVFRDIKKPIFLSCAEVDRAFPPESRHKAEAILAEGKKIYHFQLFSGVSHGFAIKGDMNNENERWAKEQSAWGIISWFDRFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1D0</accession>
    <name>M5G1D0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628897.1">
        <property type="nucleotide sequence ID" value="XM_040772781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1D0"/>
    <dbReference type="GeneID" id="63687843"/>
    <dbReference type="HOGENOM" id="CLU_1360354_0_0_1"/>
    <dbReference type="OrthoDB" id="3358172at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="201" mass="22596" checksum="EBE797CCF85A7F0B" modified="2013-05-29" version="1">MAFNPRYASTADPRALRATKSMAVFGGSMKQPGAGLRDAAYVSPFMTFRPIPGVPEPPFQYFPPTGSGSVALKGENGYLDRQRPAPPPFHHARPKAPLELLGRLPRPRPVDLLRDDMEKKMDDAFLSMPEDCQECVRMQVTQELWLKKMMDDEDAIIDTKMKYLVAMLEWLGNLQNGAHFLGFAQRVMDATLRFILANRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1H5</accession>
    <name>M5G1H5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630970.1">
        <property type="nucleotide sequence ID" value="XM_040769829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1H5"/>
    <dbReference type="STRING" id="1858805.M5G1H5"/>
    <dbReference type="GeneID" id="63684891"/>
    <dbReference type="HOGENOM" id="CLU_042546_0_0_1"/>
    <dbReference type="OrthoDB" id="2596908at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067383" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="39202" checksum="E4EA3636D51D8EE3" modified="2013-05-29" version="1">MACRTLSIFSVFLSILLAGQAAAFMRPAPHSKPTPVTRNERIARSQERLQRRQMASVTTSAWAPIETKLQTYNVTTSFGTEIWQCLTILTPTIDASGELAYEEDQSCTFTLIADPGVNPATLPAPSAPSGVLTPDSSPLATIQSALSMTPTLSATAAGATIITSVDSAGDTTFLIPAGMTSALAGGAPGTTTTVFPSSATASAGSASVGGQQAGDQGASIVGTSSIPISQVVPASSSIPTASASSDSASSSTDSANPTAQLSSILLPSSTALPDTASSSSVPAGSQLASILFGSASPSSSSAVPSGSRLPNSGALSSANDTTTTAALTIPGQTIQVLPIGLGVFAGIMVIAIIVVCIVTFERTQYRKAFRARKMAEQGGAMGYGGMAERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1U3</accession>
    <name>M5G1U3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_23428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626764.1">
        <property type="nucleotide sequence ID" value="XM_040773233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1U3"/>
    <dbReference type="GeneID" id="63688295"/>
    <dbReference type="HOGENOM" id="CLU_004965_1_1_1"/>
    <dbReference type="OMA" id="VISTQMI"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="649"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="800" mass="90549" checksum="A7DEC67B6C8EB418" modified="2013-05-29" version="1">MDNTYQPDILEYSPDLEGNIPVNQAQHLREDVAEHHLNDPNYYVQEHIQLHRVHRSTEKMTDFSSIDDRVAVEIENDLEDDSPYPEVRAAVSNTDDPTMPVNTFRTWFLGLLFTIVISGLNQFFSLRIPSVTITALVAQLVALPCGKFLERTLPTRKFHTFGYEWSFNPGPFNIKEHTVITVMANVVYGGAYATDILITQTVFYGETLPVGYQLLLVISTQMIGFSFAGICRRWLVWPSSMIFPSTLVNTALFNTLHSTYGHDDKGRISREKFFLLAFLCSFLWYFFPGYIFAALSYFNWICWIAPNNFIVNALFGFNSGLGMSIITFDWAQVTYTGSPLVSPWWAEANVFAAVVIVYWLVCPIMYFTNTFFGGFLPMVSGSSWDNTGAEYDATRIIVDGVFQEELYQQYSPLYLSTSFTLAYGLSFAALTSTIVHTFLWYRHDIIRQFRASLKDESDIHSRLMCAYKEVPHWWYAALGVISLVCGIVCIEVYDTKLPVWAFFVALGIALIYLIPVGMIQAITNQQVGLNVITELIVGYAVPGRPVAMMIFKTFGYITMSQALAFVSDLKLGHYMKIPPRLMFTAQVVAGLLACFIVVGVQDWMLGNIDGICTPEQKDHFSCPNSRVFGTASLIWGGIGPQRIFSKGAVYYPLVYFFLIGAILPIPFWLLAKKYPQSWFKYVNIPVFFTGPGYMPPATPINYAAWFVVGTFFQYFMRRYHFTWWSRYNYILSAALDSGLAISTIVIFFALSFPAHGTIGADNLALWWGNTVFLNTIDFAGTPHLALPETGYFGVPQGSWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X8</accession>
    <name>M5G1X8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624660.1">
        <property type="nucleotide sequence ID" value="XM_040771354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1X8"/>
    <dbReference type="STRING" id="1858805.M5G1X8"/>
    <dbReference type="GeneID" id="63686416"/>
    <dbReference type="HOGENOM" id="CLU_011083_0_0_1"/>
    <dbReference type="OMA" id="HRYGMPG"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="290"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="750" mass="83440" checksum="1BA1C13D97D80BE2" modified="2013-05-29" version="1">MSFPLSVSTPSWRPAIWSPDASSSRPTPFSSSPEHSGILSTSALSMHGSLPNQTTRQWNFTAFEWTVNDVKALCETIEHSSAPEGSAERVHEDEPFEILREHPSIGDGKFILEIARTPAQPRIPTTPLEGPSRSCTTATRVGPQTLSLYITSLMDHTNMDSDMTASLLVAIKCVDERGSERGTPAEWVWENWEQNWCFRKESEFWECPLPPLSTLLENQNISLTESFVICVQIHSPVGPFVPQLPSAHYIPRDLLDGFEASLDNAHTGDVAFIVLERSGSLVQSAPQSPRSVSSRLSGSRPQTARKRVIYAHSDILKSRSNYFHTMLNSAFSEASYILSKERKIYKIVVEDADYISVYWLLKWVYTNWIHFKEEDDPRVVFDTAVGSLSAQRLAGGVAEWEWRTLIRADPSADSVGSRDDIDSDVRAARSVASVESLPSVAPARHTVESIAERTTPGPDPIRRVPSTPITGNDGFSRVHAAVSTRPTSIPTSTSRKPSAIPIPTSTGSPNTGFVKRNPQPRPSKSPHLPRFPSHNLNTDPHPHPAGQPPPASALSIYKIAHRYLLPGLSNLALDHMLSTITPQSAFPLLLASHFWDDLHYLIEDYIVEHWDLVSQQDDFESCCEEVAAGEWGPHGGKTLAGLFRRLRSPSITNLAWYPYWFHEIGDSVIEQAKAEYEALMKVDLFPRDPDYRIVDIPGKGKGVIAKRRLARGQLIFSEAPIFLYNIDIKPVGLAQFYLCRVHSSPSYNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G200</accession>
    <name>M5G200_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631105.1">
        <property type="nucleotide sequence ID" value="XM_040768065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G200"/>
    <dbReference type="GeneID" id="63683127"/>
    <dbReference type="HOGENOM" id="CLU_3050267_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="6310" checksum="658F201849A8949C" modified="2013-05-29" version="1">MARREGQDDNLALVNIHHGADDLADDADDWNKEDCFYQFIASDLWIVEKDWQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G245</accession>
    <name>M5G245_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metallo-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626854.1">
        <property type="nucleotide sequence ID" value="XM_040768870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G245"/>
    <dbReference type="STRING" id="1858805.M5G245"/>
    <dbReference type="GeneID" id="63683932"/>
    <dbReference type="HOGENOM" id="CLU_031758_1_0_1"/>
    <dbReference type="OMA" id="MGYDQIN"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016814">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="383" mass="42537" checksum="66690156FB6A6F9D" modified="2013-05-29" version="1">MFHEAVYKTQEAKKAFDEDDLLERGRQLIRASISHGVTTMRAHVEVDPVVKFKCLNVGIRLKAEFSDTCDIRLVVFAQDPIFSKPLGHMDQKWTEHMMTLLEEAIDRGDGAVAAIGSAPYVEMGGKSHELANATYILDLAVKHGLDADFHLDFDLSRESRFMNLLDEVRKRPQFHCRDPPALRRNFVSPLRVTLGHCRTLSRIDPIRIGSSISVAAEGLEVYIVGLPNSDMYMKHDREPSVYRESYRTVLNPLNLEAQSSFLRGRISLSVNNVGNLFTPQGDGDPLALLPMCVGVFQNAKENSLASLIRMVTVFAASAAGLRPREHAADLMLQPGEPADLVILDGCTDWRMAALSPPFARVTLKGGRVVGKRKVETWVEGQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G261</accession>
    <name>M5G261_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="5">HMG-CoA synthase</shortName>
            <ecNumber evidence="5">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_84195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="5"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624750.1">
        <property type="nucleotide sequence ID" value="XM_040776663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G261"/>
    <dbReference type="STRING" id="1858805.M5G261"/>
    <dbReference type="GeneID" id="63691725"/>
    <dbReference type="HOGENOM" id="CLU_008065_0_1_1"/>
    <dbReference type="OMA" id="ARNGNMY"/>
    <dbReference type="OrthoDB" id="1269963at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000008">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="6">
        <location>
            <begin position="5"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="7">
        <location>
            <begin position="181"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="457" mass="50309" checksum="10EF76677EC294A8" modified="2013-05-29" version="1">MASQRPQNVGILGIEMYLPKRCISETDLETYDGVSTGKYTIGLGQQYMAYIDDREDIISFALSAVSSLLKKYDVDPLNVGRIEVGTETLIDKSKAVKTHLMDLFADAGNTDIEGIDSKNACYGSTAALFNAVNWVESSSWDGRLAIVFCGDIAVYEEGAARAVGGAGACAMLIGPNAPLVLEPVHGTHMANTYDFYKPDLSSEYPYVDGKLSNVTYTGALDKCYATYRAKMNKRFPDEKVNMDGFDYAVFHSPYGKLVQKCHGRLLYHDWLADPSLPLYSGLTEEVTAPFKNAPVEKTITDKAVEKIFVGLGKKLYQERVHPTLKCSERCGNMYTGSLYGCLASLVGSIPGQQLEGKRISMFAYGAGCAASFFGLSVKGSTQKMFEVLDLEARLAAMEVRPCQEYVDAMNLREKTHTLKDYTPVGSVDDLFPGSYYLERVDDQYRRTYGVVPEKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2E6</accession>
    <name>M5G2E6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Mitochondrial chaperone BCS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_66078</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU02864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040775802.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
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        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
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        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="196"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="44194" checksum="3F202F02B7366F95" modified="2013-05-29" version="1">MLSADTLVRRRLLTTLEIPSTDLSHPWVLSWLSRQSSPFSGRGRGFRSHQLSVNTSVNKRESGVTDVEFKQVPGEGTHWIRYRGAWMQVRRERNERMIDVKSGTPWEKVSLTTLSRDRALFDIILQEAYDLGSKAIENKTMIYSAWGAEWRPLGPPRRKRELDSVVLAHGVKERIVEDIRTFMGRETWYADRGIPYRRGYLLSGPPGSGKSSFVQALAGSLSMDICILNLSERGQTDDKLSHLLINAPPRSIILLEDIDAAFNHRVQTSADGYQSAITFSGLLNALDGVGAAESRIVFMTTNHPQKLDAALIRPGRVDMHETLDDATPAQAKEMFERFYAGQEGVEEGAGRLGEMVRDRNVSMAALQGLFIVSAEGPDMALKLLKAMLEQERVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2N6</accession>
    <name>M5G2N6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_81777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2N6"/>
    <dbReference type="STRING" id="1858805.M5G2N6"/>
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    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="NEVIFMM"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
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    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="310" mass="33906" checksum="BB0764D2C35C07C4" modified="2013-05-29" version="1">MGQAISEIFPPKPRWLPENMPDMTGKVAVVTGGNTGIGKVTCKYLLLKNAKVYLFCRSESKALAAIADLKQQTGKEALFVSCDLSDLSAIKACAEEFLAKEQRLDVLFCNAGVMMCPMDMLTKQGYDMQFGTNVLGHAYLTLRLLPLLQTTAKSFGQARIVTTSSNGHLGAPSGGFSYATLRDGPARKKLSTTSAYFQSKWGDVVWCKELARRYGKDGIVSTSLNPGAIKSELQRYMSAPLTWLVKATAYDADPYGAITQLYAGTAPEAQSLNGQYLIPWARPATARKDTEDEAAGKALWEWIQEQVKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2T6</accession>
    <name>M5G2T6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_17176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627049.1">
        <property type="nucleotide sequence ID" value="XM_040771264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2T6"/>
    <dbReference type="STRING" id="1858805.M5G2T6"/>
    <dbReference type="GeneID" id="63686326"/>
    <dbReference type="HOGENOM" id="CLU_569888_0_0_1"/>
    <dbReference type="OrthoDB" id="10264980at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067427" evidence="2">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="46906" checksum="1D9C784A9AB03991" modified="2013-05-29" version="1">MLCGRTSLLLLVIWGSAVGVIGRPPLARNDAELQVRQASSSGSGGAPSSASVPTSSSTSAQETSTTSTSSISTSTSASTFTSASASTASTTAPTTSTTPTTATTSIPGTNPLTGSLRYFPSASSSVASSEAFSLSGSSSSLQGSSSSSSVSSGTTSAASSASSASSAAFLAPPPQSAAGNQSSSSTSLSTSIASSPTQTSSVVVGTNATSSAPSTAVATEFVSQFTSGSIVSNVTVQTTMLVPATPNAPPTIIPELSVLTSGASTLTITAGSVTLNALAATLSASSAQPSATMPADAPKMNATVPASSNNITYSTGSWTPYDLTNSGGGSNGSGVGSGSDGSGATPLASNLDNQNVPTNLQCPSTVAPQDTRSSTDLGATVVYSFVGTAIFAQLVPRNNSGIYSAWVDDDVPQTYDGYQMFATQQQALPGSPPSCQLGFSATGLTNTTHTMHIKIVAPSTAQQNEGGGGGTGLTLAGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Z8</accession>
    <name>M5G2Z8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629494.1">
        <property type="nucleotide sequence ID" value="XM_040768310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Z8"/>
    <dbReference type="GeneID" id="63683372"/>
    <dbReference type="HOGENOM" id="CLU_013084_3_3_1"/>
    <dbReference type="OrthoDB" id="2665372at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22390" checksum="DE59B2C06C7B4A37" modified="2013-05-29" version="1">MLCDLHGHPHKPHLHLQLSQAYNVYVLMLLELEEMVQHALGHDKPNWHMLNACPACNYVLEGEPELAHSKLISLDGNNSSKCFAQAGDQDLCTFKSNYLLSPMFIDEFKKEPTHGRTHSAKELPKENKTKTEPDEDNCTDKSKTSNAKEQSSHQMDGLDATGNFLCTWCHGMVVCLANMLQSSELCVFKKLKLKPLLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G305</accession>
    <name>M5G305_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_95563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627114.1">
        <property type="nucleotide sequence ID" value="XM_040777304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G305"/>
    <dbReference type="STRING" id="1858805.M5G305"/>
    <dbReference type="GeneID" id="63692366"/>
    <dbReference type="HOGENOM" id="CLU_662258_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="49056" checksum="B4AEC271B571D863" modified="2013-05-29" version="1">MFSLWPTFSRWLWFPLWRIGTTAAIVLASLLKQVNAILYWDDRPVILEEDDVNIWPPNIRPRNIKRALNRRMHGRDRCVDVQYLSHGASHVVLLAKTSYKEEYVVRVTGSVYEHFQWAHPFWQTYKETSEVASMVALRRLTKIPVPRVYLFDEDRDNAVGGVWTLQDYMEGERLYEFLPELSGEALEQMLQVFHLEFSQIGSLHFTRPLNEIRDVCDDDLEIRVGRLVTLRDLRMENEYMVGSPKDTDMGPWDSSKAWLKSIAQGDMDYQSSFVELDSNDEHIRRIQRIIDEPEESNGLFTSGPLSVNAPWCTDMWNTHNIQAVCKDGTVKLVALLDMEGMQIVPRWVLGRLPLLDELPDESSRVLWKFLLEDPLYKQAHEQGSKARHLLVLAQNASVPHWADKRIEEFRDGDWEDNGTLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G335</accession>
    <name>M5G335_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="7">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PAN3</name>
        <name evidence="11" type="ORF">DACRYDRAFT_23226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G335"/>
    <dbReference type="STRING" id="1858805.M5G335"/>
    <dbReference type="HOGENOM" id="CLU_016423_1_0_1"/>
    <dbReference type="OMA" id="YVFHSVD"/>
    <dbReference type="OrthoDB" id="204958at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3700:FF:000001">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5160:FF:000002">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03181">
        <property type="entry name" value="PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25586">
        <property type="entry name" value="zf-CCCH_PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Knob domain" evidence="7">
        <location>
            <begin position="564"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="525"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="361"/>
            <end position="368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="425"/>
            <end position="426"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="658" mass="73218" checksum="71D8EA9C8AB25464" modified="2013-05-29" version="1">MSSAIPIVAPTAGTEQAVDRTARPAKKDQLQRRTQCRNELIYGSCKFADNGCPFYHPSKDSSVSIATSPAPLVANSNPATPAPKEMPAGPSANNTPSKGGSGLGGLSATVNAPIFVPKGFPSMLAGQPSTPTTSTAPSTSPESTKTTQPTEYDYGDDFHFDYLDDTPYTKAPEITALAPPFVPSSQQAVESYHPGMDPYAHEMNPYYAEHPLYPRQPLQYHLYNPPLPYMTNIPSSANPFLADDVREMLQRRSEAIMETSTVDYKLPDELHVYHSLVPIEPPGETRHPRVFQWPSISYKAISAKDGRPYILRRFEGFRLMHEAAFAAISIWNQIKHPGIVTLYEAFTTRAFGDSSLVFVFDYHPNSESLYMAHIKPKQPPAKVGRSQLHAPILPEAVMWSYVVQLADAMRVAHSHNLALRTLELTKVLLTGKTRVRVNCCGVFDVLNFNPAHNVIGFQQNDYMNFGKLLLELACNSTAAATNLPKSMDMVSKRYSPDLTKLILYLISPAGPPKNLDKLFEYIGSRRVLEELDTVSNYSDSLEGELMSELENARVVRLMSKLGFINERPEFDHDPRWSETGDRYIIKLFRDYVFHQVDIHGNPVVNLSHVLVCLNKLDAGVDERVMLVSRDEQSCLVVSYKDIKSAIETAFSDLSRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G356</accession>
    <name>M5G356_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DDE-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631545.1">
        <property type="nucleotide sequence ID" value="XM_040767945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G356"/>
    <dbReference type="STRING" id="1858805.M5G356"/>
    <dbReference type="GeneID" id="63683007"/>
    <dbReference type="HOGENOM" id="CLU_657240_0_0_1"/>
    <dbReference type="OMA" id="RVENFAP"/>
    <dbReference type="OrthoDB" id="162969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="2">
        <location>
            <begin position="107"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="418" mass="47809" checksum="1BB7CA96857ACD39" modified="2013-05-29" version="1">MTTKRKARSAPASAGKGKKPWKENLTLAQRLEILDYIKANPIFSQLDVAKYYTARSVPFSQGTVSRLIRDEVILRERAKDPARLNDKRQRQVEFPEVEHALAEWVRQAEGQDLGHNYFWNRKSWMKSDIFEQYLSEFDHYQKELGRHALLLVDGFSAHKIDASKFTNVRVEILPPNMTSHIQPLDQGIIRCFKAHYRSKTIHRAIERESGGADMQHMYEINQLEALNLAEQAWWEVSEKTIQNCWRHSGILSLGTAAGTVMPTGLDEPLIVETPPTLIEQEEGMQDAIQELQSSLKALQERGIIAPAAMMSVEELVTVQEELEVPEMWTDEELLQQAQDEIQAAQGVSQPEEDEEIIELPIWSDQKMLAACTELERALRARAEPDLRTLLSSLPSAIRTLRHQQSLSLQQRTVSEYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3B1</accession>
    <name>M5G3B1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627264.1">
        <property type="nucleotide sequence ID" value="XM_040770371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3B1"/>
    <dbReference type="GeneID" id="63685433"/>
    <dbReference type="HOGENOM" id="CLU_915343_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="304" mass="34025" checksum="4D32F2C55AE4899A" modified="2013-05-29" version="1">MHDHDEAVVTADASEGSVASLNDNDASTYGTLPSDDLPDEDTLAELVEQAVSLSGDTTMVETTSHDVTHGAWTRSTLEHHLKHCGSEGTIRLHLNLTVLTESMNMRDAMFDQLRDLIDYWHHVRALRMNIDDWAIGPLETSNYINAELPLRSLSVQDLLRHSERIVVRVVDAVQLHTIKLARASIQLVTVESKPVNLAGLEKVALMDAELFCISAEAHGKHAEAPRKIMSPIERTRFSLACVSSVQHLVLQKSNIVEGMQAVEFLRLQSLKINDRPLQILYLVRALNMPYLQKCFLLFPNCISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3M8</accession>
    <name>M5G3M8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630173.1">
        <property type="nucleotide sequence ID" value="XM_040772422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3M8"/>
    <dbReference type="GeneID" id="63687484"/>
    <dbReference type="HOGENOM" id="CLU_2885715_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="63" mass="7013" checksum="CFC8166EF8E3C309" modified="2013-05-29" version="1">MFRGFKVQRGRNGGRICRKNDEDNIGYLASQFSTESDRITGSSFLPVSGSDLSERPDNSARDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3M9</accession>
    <name>M5G3M9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_21769</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasmic vesicle</location>
            <location evidence="10">COPI-coated vesicle membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629719.1">
        <property type="nucleotide sequence ID" value="XM_040772545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3M9"/>
    <dbReference type="STRING" id="1858805.M5G3M9"/>
    <dbReference type="GeneID" id="63687607"/>
    <dbReference type="HOGENOM" id="CLU_006949_0_0_1"/>
    <dbReference type="OMA" id="IYKNFDW"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000451">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="12">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="13">
        <location>
            <begin position="674"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="14">
        <location>
            <begin position="814"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="951" mass="105440" checksum="17FA1A49738F6D7A" modified="2013-05-29" version="1">MANPDATCWTVVFDDAQELPTTAELRQALEKGSDDVKLETLRRIIIATQNGQPQPALLMPIIQYVLPSKNKALKKLLHFYWEVCPKYDDNGKLKQEMILVCNAIRNDLQHPNEYVRGATLRFLQKLTDAELLEPLVPTARACLEHRHSYVRKNAVFAILTIHRNFEHLVPDAPELVQTFLAAESDMTCKRNAFVCLSQLAPEKAAEYLLSVLDQVPNFDELLQLSVIDFIRRETKDSDPSRRARYIRCILELLNATSHSVKYEAATGLTSLTQNPAAVKAAASCLIELAVKESDNNVKLIVLDRLETLRAKHEHVLDSLVMDMLRILSSPDMEVRRKAIGIALAMITSRNVEDVVLFLKKQLSRTLDNEFEKNAEYRQLLIQSIHVCAIRFSEVAANVVHSLMEFLGDASNSSAIDVIAFVREVVEKFPGLRKSIVEKLMQTFGEIKSGKVFRGALWIAGEYASDTDDILEAFQEIRKVLGEIPILASEQRLLDEAGGDEEAGQSLDGTAAPHKPRLLPDGTYATETAFSTTAAQARLEAVKAAAKPPLRALILGGDFYTGVVLATTLTKLVMRFSELAKDKKKVNVLRAEAMLIMTSVVRVGQSKFSAVPIDEDSQERILNCVETLAQLANEPVVKEIFLTETKAVYAKMVATEERKAAEKKAKETKASAIQADDLITFRQFSKKSALDGVDDYEQDVTRATGSAETSEDLISDLSRVVQLTGFSDPVYAEALIKVHGFDILLDVLIVNQSSDTLQNMCVEFATLGDLKLVERPTTHTVGPHSFLSVKATIKVSSTETGVIFGNIIWEAGTNEACVVLNDIHIDIMDYIKPAYCSETQFRSMWTEFEWENRVNVNTTITDLRAYLAHIMKSTNMACLTPEAALSGDCDFLSANMYARSLFGEDALANLSIEKVESTGIIQGHVRIRSKTQGIALSLGDKITLAQKAIPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4S4</accession>
    <name>M5G4S4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleotide-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_22731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627759.1">
        <property type="nucleotide sequence ID" value="XM_040772934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4S4"/>
    <dbReference type="STRING" id="1858805.M5G4S4"/>
    <dbReference type="GeneID" id="63687996"/>
    <dbReference type="HOGENOM" id="CLU_034311_3_0_1"/>
    <dbReference type="OMA" id="GENNIMY"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="47"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="37380" checksum="099E26CD31496511" modified="2013-05-29" version="1">MQLHQTPVVVIGCGVAGLSAAYQLADAGYLVTILAKEFPGENNIMYTSDWAGASLGFAAGGSFRARRVSQETFQTFWDISSRYAPEECGICRITQETYFDKKPDPSLIWYSKEAPDFRILSPSEYPAQYAFAVSYTSMTLEPPRYLPWLVKQVQSKGVKIMRVEVDSLRAALDHIPDAKAIINCSGIGSRYLKDVKDDAVFPERGQTCAIRTSFKKLIIRSGAEYTYLIPRPLSGLLILGGINEPFNTSPEPNPASREMFKQRAHKICPELGPVDQMEFVMDIVGVRSTRKGGYRLERQEGGKLPIVHSYGYNGGGYQASMGAGKEVVRLLRGEDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V7</accession>
    <name>M5G4V7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_110676</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625680.1">
        <property type="nucleotide sequence ID" value="XM_040769100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V7"/>
    <dbReference type="STRING" id="1858805.M5G4V7"/>
    <dbReference type="GeneID" id="63684162"/>
    <dbReference type="HOGENOM" id="CLU_013783_3_0_1"/>
    <dbReference type="OMA" id="ENEWANF"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
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        <property type="term" value="F:serine-type endopeptidase activity"/>
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        <property type="term" value="F:tripeptidyl-peptidase activity"/>
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        <property type="term" value="P:proteolysis"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Peptidase_S8/S53_dom"/>
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        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
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        <property type="entry name" value="S53_propep"/>
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    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
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        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
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    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067568" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="19"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="209"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="556"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="574"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT98782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="596" mass="64562" checksum="A13EE8B8CE5D9C8B" modified="2013-05-29" version="1">MRSLYTLLLSLAALSAAALQPRAGYACKDRSAAPGWHNLGPARPDRTLTLEIAFKHNDFAGLHEQLLLRSDPESGMYGRHMSKEEVEAFLRPGEETRDAVLGWLEEYGLGEESVRWSPAGDWAFVTVIVEKANRLLDTEYSVWHKDGHTILRSGAYSLPHELFAHIDTIQPTTDFSIMRKHGALPMSDEDVTAIEYNAAATEWGTCNTTVTIKCLQKLYKTEGYVPRAVEVNRLGVAAYLGDDANLDDLNEFLSLQRPQAVGHANFTTVPIANGTNPQTNLSGTTESALDIQFTTGLTWPTKITFFETGGTRPHLYDAANQTGNANFLSWLTYVSALPDEELPSTFSTSYGSEEVTVPIDYAQRVCAGLAALTARGVSLMYSSGDSGVGYASANFCVNPNDLSQKMFLPNFPASCPYVTSVGGTQNIPNEVAVTRFGSGGGFSNFFARPAYQEAAVSRYLSWLGSDLEGWYNASGRGFPDVAAQGDRFQIVAPAYLTVKSSNGTKVGLVGGTSASSPTFASVVALLNDVRRSQGKPPLGFLNPLLYRRLYLGLNDITVGSSFGCNTTGFPATYGWDPVTGLGTPDFEKLVALLEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G594</accession>
    <name>M5G594_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_118235</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625825.1">
        <property type="nucleotide sequence ID" value="XM_040770546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G594"/>
    <dbReference type="STRING" id="1858805.M5G594"/>
    <dbReference type="GeneID" id="63685608"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT98927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="719" mass="82140" checksum="651F4E3C3B986A15" modified="2013-05-29" version="1">MLYSGLILVVALVFAVGIRDAYRKRISQLLPGPPGLPILGNLLQLPSQFLYRKLTSWSEQYGPFYTFWMMNQPFVVVGNTEIAADLLDRMSAMTSNRPRMIKAREFYMRDMAVVLQDRSHVWRAQRRAMHANINVKTASRFNSMQSHDAAYLALGLLQHLETPLYEDTHRFASSIIFCSLYGGNAIPLDGPDPSKEAEELTDQGLHVTIPQHSVVDTMPFLEPLIKRNWDATTIVQDLQQNNEKYELERSQAMWMTMIMFMAGQETTNTALRAFTLAMRIRDDNYTYGRKRRVSPWVKIAMSAVTSDRPRMIKAREFYTKDMSLVLQDRSPKWRAQRRAIHANINIRATSRFNPMQTHDAAYLTLGLLQHPEKPFHEHAHRFAASIIFGSLYGGREIPIDGPDPSQTVEELTDRGLHFSMPQHSLVDALPFLKPLIMRVKWFRRPADIWFADSVREATLLYDSAKATDNWDATTIVHDLRLNNEKYELEKAQGIWMTMVLFMAGQETTNTVLRVFTLAMLHHPDVVQAAQRQLDAVCGGRVPGFEDRDNLPYIQAIVKEALRWRPAVPLSVPHRATEDFEYRGYIVPKGTIILDNLWGQTQDPMVYAEPETFKPARFLDSSGNLRPVTPDTRLDQLGFGHGRRACAGRNFAFNSLFIACAYMLWAFDFKWPLDKNGNEIICGVHDLEDKGIVITPKPFGVVLKPRKDGLENRLLAALGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5D6</accession>
    <name>M5G5D6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630339.1">
        <property type="nucleotide sequence ID" value="XM_040768115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5D6"/>
    <dbReference type="STRING" id="1858805.M5G5D6"/>
    <dbReference type="GeneID" id="63683177"/>
    <dbReference type="HOGENOM" id="CLU_1209793_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="26046" checksum="0EAD916AB6B252C0" modified="2013-05-29" version="1">MSHVEAPALRSLTLRGLNHEGLRAGGIMQVLARHKLPLETLYLRRLTYETNELLDFLSSVPTLIRLSFEESCLGRDAVEGMKARHPRTNTSCPALIKLFIKHTRTEDIANYHPYTMTGLRSMIRSRCYSDCVSKISSLSVQDAHIRILQETRGQFREYVNELSLNDQPVQMHFHDSDESNLAGPPLSSVNQEFGNDFPFDEEAPFLEDITSGHFIFDGVPVQWSIQLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5K7</accession>
    <name>M5G5K7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName evidence="7">U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_82949</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UTP25 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625940.1">
        <property type="nucleotide sequence ID" value="XM_040776601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5K7"/>
    <dbReference type="STRING" id="1858805.M5G5K7"/>
    <dbReference type="GeneID" id="63691663"/>
    <dbReference type="HOGENOM" id="CLU_018705_3_0_1"/>
    <dbReference type="OMA" id="QDRGDTF"/>
    <dbReference type="OrthoDB" id="10264378at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="10">
        <location>
            <begin position="186"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="9">
        <location>
            <begin position="452"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="639" mass="72525" checksum="DFCF1E555EBB2A40" modified="2013-05-29" version="1">MDDDNFNSVSTKLLTLLNVSATRRDKKRRPNDDIKPPGKRITLGGKPKAVFSTTVVSSTFVARAIDGQIDSKPDADIDEALEDDLEVADVKDPFNDHFGAKQSSLSPSALNALDEGKWTTRQRKIGSLGAFQELLLLDNASEVQLSAKVSSAESAKLLASFKSRLDTLNDEMRSLCADFAKLAGTYEDVFVSDRDGRKQQAFREAISVHALNHNNDRLAHFDEAAGGDPPSDVQDQGFTRPKVLFLLPLRNSALSWIETLISNSPTSQTENHSHFLAEYSLPKGVSDRLAENPENYPRDHVDNFEGNIDDNFRLGLKLTRKTMKLFTEFYSSDMIVASPLSMKMLIEKDKSKSADFLSSIEILVVDQLDVMSMQNWEHLQFVLGHINKLPNETRDSDFSRIKPWYLDGHAAKLRQTLLFSPYETAEMRALYKSLTNVAGKLKTEQRFTGLLTQLPKGIQQTFMKFSCSSPLQEADARFEYFTKQVMPSLLKSAVRSVNTMIFVPSYFDYVRLRNHFKDTGAISYTTLSEDVSNSEIARARQQFFAGNKAFVIMTERFHFYRRYRIRGFKNITFYGLPDHGNYYDELLAMPFQDAEDTEGSDLFVQAIFCQYDFLRLERIVGTQDARKMIKSQEDVFTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5R8</accession>
    <name>M5G5R8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_21110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630454.1">
        <property type="nucleotide sequence ID" value="XM_040772238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5R8"/>
    <dbReference type="STRING" id="1858805.M5G5R8"/>
    <dbReference type="GeneID" id="63687300"/>
    <dbReference type="HOGENOM" id="CLU_029481_1_0_1"/>
    <dbReference type="OMA" id="KRTHNGH"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007224">
        <property type="term" value="P:smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000634">
        <property type="entry name" value="Zinc finger X-chromosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="42046" checksum="12A7CC224B1F921B" modified="2013-05-29" version="1">MGMGPSFPGPGSRTPSLVGSLQSSPAPSMYASPSLLFSCQWSQCHMSFATLEELKAHVDSQHLHLPGVHCAHVAPPLHHTHVPIQAMFDPSLFGMDQNGATECLWGDCGSELPPELEPGSIASALAMAEHLLQDHLNLGPMDIDPSLSHPTPVASMPTISPVSPTFSLNSQTASRASCSTTEEHVCEWQNCNAVFSSAAELMHHLTNYHVGSGKNEYWCRWRGCDRNSEGRAFASKQKILRHVQSHTGYRPYECDVCHQFFSEPATLQQHKRRHTNERPFVCDYPGCNKAFAIAGALTIHKRTHNGEKPFKCTYCDRAFSESSNYTKHLRTHTGSKPYLCPEMGCGKRFSRPDQLNRHLQTHKTAAHARTSMDESDDDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G612</accession>
    <name>M5G612_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_93945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630549.1">
        <property type="nucleotide sequence ID" value="XM_040777186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G612"/>
    <dbReference type="STRING" id="1858805.M5G612"/>
    <dbReference type="GeneID" id="63692248"/>
    <dbReference type="HOGENOM" id="CLU_028484_1_0_1"/>
    <dbReference type="OMA" id="LPFAPNM"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="532" mass="61512" checksum="874E833A677202A0" modified="2013-05-29" version="1">MSLQLSRAGHSRAGPLILARRGGLACSRGRKQREYTSQQKQYAPKHETNPAKYNWNPNNFTDELPKNYEKYPLLTASQLSREKKPRREVKMLVRDFIADALYNPNYGYFPKQAVILSSPEPFDFPSLKNSDEFNSMVARTYATDDTGPRTLIGRQLWHTPTELFKPWYGSAIAQCLTADYMLKYFPYEDFIIYEVGGGNGTLARNILDFVRDYYPDIYERTSYRIIEISPQLAEIQKQQLKQEHENVEVIIKDILQWDKPDLSPCYFIAAEVIDNFPHDIIRYRTEDLKPAQCVVVVDSEGSYTELYEPITDPLITRFLAYRTALHHQPPVLTRVMTSPVLRFLRQALPMVPNLSSPEFIPTHLLLFLEKLRRNFPQHRLLLSDFFSLPEALSGYNAPVVQTRYRGAMIPCTTYLVQPGYFDIFFPTNFERLGELYELVMSLPHTPQELDIRSSPILQSDRRLASDFFSARGRSDVEPTPVLSGKPARLGPPLCNIFTHKEFLTRYANIEATTLRNGENPLLEFYQNAKFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G617</accession>
    <name>M5G617_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="4 15">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_92921</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="14">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="4 15"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632590.1">
        <property type="nucleotide sequence ID" value="XM_040777114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G617"/>
    <dbReference type="STRING" id="1858805.M5G617"/>
    <dbReference type="GeneID" id="63692176"/>
    <dbReference type="HOGENOM" id="CLU_029960_0_0_1"/>
    <dbReference type="OMA" id="CFENRGA"/>
    <dbReference type="OrthoDB" id="418412at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00608">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000001">
        <property type="entry name" value="Galactose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943:SF1">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10 15" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="8 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase N-terminal" evidence="16">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase C-terminal" evidence="17">
        <location>
            <begin position="217"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="12">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU05696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="373" mass="42018" checksum="B326E03AC71D3C8F" modified="2013-05-29" version="1">MATDPPVFDPSEHPHRRYNPLLREYVLVSPHRMKRPWLGQVEPPAADTLPQYDPKCYLCPGNSRSEGAVLPQYTETYTFANDYPALLAGPLPPAPPAPHPLLITEPVLGGCDVVIFHPRHDYTLARLTVGEIEKVVVEWTRVFVQRGMQEGVKYVQVFENKGAIMGCSNPHPHGQVWSMSSIPQIPSVELRNLVKYSLSPPPDPPSGAPRGDKGKPCMLCEYAHFEKGAGERVVLEEGPWVALVPWWAVWPFEVMLLPTHRHISSLLDLTPDERTSLSTAISRLTKRYDNLFSCSFAYSMGVHQRPTPMQLDDEGEAAHLHLHFDPPLLRSATVKKFLVGFELMAEAQRDLTPEQAAKRMRELSEVHYLDLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G627</accession>
    <name>M5G627_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_77371</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630564.1">
        <property type="nucleotide sequence ID" value="XM_040776267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G627"/>
    <dbReference type="STRING" id="1858805.M5G627"/>
    <dbReference type="GeneID" id="63691329"/>
    <dbReference type="HOGENOM" id="CLU_669057_0_0_1"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="175"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="411" mass="46286" checksum="9D12D672E55A4BAA" modified="2013-05-29" version="1">MDLSSQTSQPGVPRGKKRESPKGKSWIDPSERVLKKSRLEDGGEKPALIDDEAEIPTGSLSSMRISSSPSPVSSGMNEAETKELCPFCDEPWPERPSKRLTELLKQVKPRAWKDPRYSNPDGLSAPLEIFVSLCTLHRSETSHIPEGIAQGWPTTLDFNRIPKRLEQRKDSLKAIISSPSASPFFQAAKNDIFEKGTRVAGSVFGQYETFERCQPGYYGEQGMITIQRALMFMFPNMVASNTRPLSVDDFIRQVLVPEAAILLIRQDLQLSRAKALQVLLKSRKYGLAQFPDRDGGETQWQDNNHARVHRLQNSPSLHTFPDDTISPVIKTSSTTRTTKRQLKPVKVDWSYKFRDNDTASSSCPNEESVEIVDITESPLRPPTSRKDGHGDRWPLGSSDEETFHLRKPKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6J5</accession>
    <name>M5G6J5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628339.1">
        <property type="nucleotide sequence ID" value="XM_040770236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6J5"/>
    <dbReference type="STRING" id="1858805.M5G6J5"/>
    <dbReference type="GeneID" id="63685298"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OMA" id="CTQEVMD"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="42059" checksum="423FB2186DB22183" modified="2013-05-29" version="1">MSKKRGSAPGAQVLSAYKSAIQHIKIILVTPASMGKFRLWPWFCGLYKRFPTPEQYGADLTSKTVIVTGANAGLGFETAKYLARLHPGKLILACRNLQSAEEAKTLIIADTKCETVECWKLDLSSFASVQEFVSQFEREGGGKLDLLIQNAGINHHGPHKTTSDGWEVQLQVNNLGPELLGLLLLPYMAKAGPTPPTPRMVWVASEMHYYVAVGKEPQGSLLEALSKDGTFEDTVQMTFSMFSKEKARYPMSKLINVMFARSLGSRIPASSGLTVVSVNPSACASSLQRDLDHLLLVRLGQRWFFRTAEMGSRVIAHAALGLEVQGKQGAYYNDCKEEEVCDWLLTEMGQRIQERIWKETIDVLSRVDGRAPGIIDEYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6P4</accession>
    <name>M5G6P4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF757-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628389.1">
        <property type="nucleotide sequence ID" value="XM_040772888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6P4"/>
    <dbReference type="STRING" id="1858805.M5G6P4"/>
    <dbReference type="GeneID" id="63687950"/>
    <dbReference type="HOGENOM" id="CLU_103791_1_0_1"/>
    <dbReference type="OMA" id="IQFYAFE"/>
    <dbReference type="OrthoDB" id="10248897at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="1">
        <location>
            <begin position="16"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="18916" checksum="D693C51665B048D4" modified="2013-05-29" version="1">MAQPFDPETAENLIEIDKQFAVRTVEHAQTHWNLITRIPPRKLKLTPIDDEIYEDFKKGFPELADFPDKLSKLDDEDLKSPEAKKRWREWMAKYEKKLKDYNFGTLLRNNAKEEYGEHNAMLVLKIQWCAIEIARNRLGLNDYVYDETQRQMQAAAAKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6U2</accession>
    <name>M5G6U2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631318.1">
        <property type="nucleotide sequence ID" value="XM_040768094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6U2"/>
    <dbReference type="GeneID" id="63683156"/>
    <dbReference type="HOGENOM" id="CLU_1875365_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="14652" checksum="3315787F1764EB6E" modified="2013-05-29" version="1">MDQQLPLIPLTIFGGGLLSGVPELPELYGDIMLDLEDIVDWRTLEDDPTMLEMDGASTLWGSEIGSVQNSPNFTISDPPAVPVSKESDFLDHTMTPIPRRMSTSSSPSCFEDVAHMGVLSAKGPGFPAPFTTKVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Y7</accession>
    <name>M5G6Y7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626420.1">
        <property type="nucleotide sequence ID" value="XM_040767536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Y7"/>
    <dbReference type="STRING" id="1858805.M5G6Y7"/>
    <dbReference type="GeneID" id="63682598"/>
    <dbReference type="HOGENOM" id="CLU_477357_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="571" mass="63827" checksum="7D6BA47EFDB2A1AE" modified="2013-05-29" version="1">MALKRSEYSNQRLDKDGIYHVDVRQPGDSTISFHVPLDDILGISERRAVSGQKGFFSSKLTDDVHLDAKDLWKLRYKACSVEGKNDWMISAYDLFKIVNFENGKVLSIGGYQSSTVTNTESTTNSEMASDSYSAERHKIEERLHRTEGRIADLSRTVSSDLLNIAKVYGDYDSFVVEIKKRDTQMALILQDQADIYRGLSLAYQRLSRADIEHTTVTTEQTRTASQSASITESKTTIEKERTTLQIETDRLRKELLVVRSQNDEREAASGTIRAELEEARTTIIANSVIIKQFESWKALYMGQVQTMKKELFETTEVMTRLEETYQETLRALRKAKIEKEELQSTLILTKSSQTEVDARINILEQALQDARAELWRVSQAYTEKMDGFDGMSTTKAELERRISELTLSFAHERNVTRSLSERLLQIQGSMSASLDWIYDMRHDLTDESSYIHSGHFHSGGGLGSVLERQFRPRLPSYGSAVKTGLKISESKTYNANGIERENSSNGTTTAILSTTADGTGSVGGNSNGDTGPTTTTQSFSGRPPSREDIKLVSPIFESDLGTAVPTATGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G752</accession>
    <name>M5G752_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial intermembrane space import and assembly protein 40</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Mitochondrial import inner membrane translocase TIM40</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_48365</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630929.1">
        <property type="nucleotide sequence ID" value="XM_040774826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G752"/>
    <dbReference type="STRING" id="1858805.M5G752"/>
    <dbReference type="GeneID" id="63689888"/>
    <dbReference type="HOGENOM" id="CLU_1378075_0_0_1"/>
    <dbReference type="OrthoDB" id="7481291at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039289">
        <property type="entry name" value="CHCHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622:SF0">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CHCH" evidence="13">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="128"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="198" mass="21607" checksum="1CD964138FF934E6" modified="2013-05-29" version="1">MSLVRTSLAHRVRNCSELWAVAASPKAPSDEEIAEEIIHEKAEEAEETLEESDKEAAFDPVTGEINWDCPCLGGMAHGPCGQQFRDAFSCFVYSNEEPKGINCVEKFRAMQDCFREHPDVYGEEIMGDDDEREDADAPAPALAASDVSSETPATILTDPRVVTVDELSATDVPPLPNAHPPASSPVLQTDSRTTGRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G761</accession>
    <name>M5G761_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628549.1">
        <property type="nucleotide sequence ID" value="XM_040768603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G761"/>
    <dbReference type="GeneID" id="63683665"/>
    <dbReference type="HOGENOM" id="CLU_1184970_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="25851" checksum="93113CDEF6EC0CD6" modified="2013-05-29" version="1">MVGTSTSSQVLELGFTSTLSETLNPMLSTLILGALALLAQPTHAISWGLFTPSGNPWIQMVFTQHVPQGPPSDVNSGPWFFWCGLQPNGGGVLQPPGNQGQPDGLPAIQSEGFWVDEGAQIVGTVTWENGQWGQTAQVISGQAAGQSISLTSQTNYFQGETPGFDNTNFAVCDAELDGSQTGEWNFPVVFTDLFIRAATSDGIEALCADTANPVHSAGAGSIQFEGFSMLDAETCHWSTVTLLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7F5</accession>
    <name>M5G7F5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ERAP1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628684.1">
        <property type="nucleotide sequence ID" value="XM_040768491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7F5"/>
    <dbReference type="STRING" id="1858805.M5G7F5"/>
    <dbReference type="GeneID" id="63683553"/>
    <dbReference type="HOGENOM" id="CLU_1133557_0_0_1"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="1">
        <location>
            <begin position="156"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="27342" checksum="56BAE4F140BDAC2C" modified="2013-05-29" version="1">MDSKVVLTAKEATFNIPMWKLGKLTLYKLNARIIGVYHVLYPPDHLSKLGDEAGLSSVPLAEKPGFEFSENDSPDLTQWRITAITNAANAANAANAANANDPKTIAEVKRRFNLLLEKNDLFRIAGDLQRTIYANVVRLGGKTAAMIALCRSTDPALVKPSQTHLSNLVEKFKGNFSLGRVLQYSFDSLTTFEDVNVIEGFFEDKDTSTYVQALSQGLDDVRSKAAWLERDRAEVEQWLKKNQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Z8</accession>
    <name>M5G7Z8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_75873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631778.1">
        <property type="nucleotide sequence ID" value="XM_040776165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Z8"/>
    <dbReference type="STRING" id="1858805.M5G7Z8"/>
    <dbReference type="GeneID" id="63691227"/>
    <dbReference type="HOGENOM" id="CLU_059988_2_0_1"/>
    <dbReference type="OMA" id="PLEWHMI"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000007">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="265" mass="29054" checksum="49C7C4907835EF2B" modified="2013-05-29" version="1">MSTSDYPRPSSERIAELRENLEAIRAKINVVVSSAGLGDKKPNLVAVSKIKSAEDVMACYEDGQLHFGENYVQELIEKAEKLPQEIKWHFIGALQSNKCKPLASIPNLYAVETLDSIKKADVFQKSLPDARSIPLRVFIQINTSSEESKSGLPPVSSTSSGSEAVELAKHIVQKCPALHLEGLMTIGSIEASTTQDENEDFDRLRDSRDNMEKTLREAGLLEGWGQDGKLQLSMGMSADFENAIMQGSDSVRVGSSIFGARPKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8J8</accession>
    <name>M5G8J8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21019</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631389.1">
        <property type="nucleotide sequence ID" value="XM_040772191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8J8"/>
    <dbReference type="STRING" id="1858805.M5G8J8"/>
    <dbReference type="GeneID" id="63687253"/>
    <dbReference type="HOGENOM" id="CLU_004962_8_1_1"/>
    <dbReference type="OMA" id="KIGGYPP"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="109"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="35693" checksum="F5A826F316519A1B" modified="2013-05-29" version="1">MPFDLDHCIEQLLHKRLLGEPLIREICEKTKEVLMRESNVVHIQAPVTVVGDIHGQFYDLVEIFRIGGYCPNTNYLFLGDYVDRGLFSVETITLLTCLKLRYPDRVQLIRGNHESRAVTQTYGFYTECIRKYGSPNVWIYFTDMFDFLTLSVVIDDRIFCVHGGLSPSIHSIDQIKVVDRFREIPHEGPMADLVWSDPDSDKEDFAISPRGAGYTFGSQVVRKFLEINHMSHILRAHQLCMEGFSVSFDNRLSTVWSAPNYCYRCGNSASILEIGPGQEMHFNVFEAAPENERDGPQQAQQASMMKIEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Q3</accession>
    <name>M5G9Q3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RCC1/BLIP-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632433.1">
        <property type="nucleotide sequence ID" value="XM_040771750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Q3"/>
    <dbReference type="STRING" id="1858805.M5G9Q3"/>
    <dbReference type="GeneID" id="63686812"/>
    <dbReference type="HOGENOM" id="CLU_021989_0_0_1"/>
    <dbReference type="OMA" id="YDQPHEI"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053245">
        <property type="entry name" value="MitoProcess-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563:SF1">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="343"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="566" mass="61176" checksum="6DBBA024A0455964" modified="2013-05-29" version="1">MSSQARLLATGIRRTLKQPRQVQLALAAAVGVTAITVFGAGLVYNDAAPPKKTTGAVAVQPIQDSTDSLTAWSWGSNDYRVASSSASTTKAIRNPQPLPHLSGIALRDLALHEKHGACVDAAGNVYQWGDEFFENKSKEARKPKLTLTGKDIKSLTITESKVYALSSSGRVFVLSAKESRHGNIKEESSPWWTTSWLWHTQPTLDHVELKPEFPLRGREKFTSISAGRDHLLALTSAGRAFTHAVNAKANDYGQLGISRISARISSNPPQDKPIDLIPKASKDPSEQSTPFARPTAPPLPVAGDDTDIHWSTKLYEVPSLKEVKGKQLIAGGRSSYLLTAEEGRVLSWGANEYGQLGLGATMTLTSVPIPTEVVLSRPYPRGAAVRCTHISTGGDVVYFTMERTIPGENTAGVDVLAAGMGQWGLLGNGQYTQSQGSPVKVRAVSGIMEYNDKTKALEALQPRAISVSPTGHAMLTLDTISDTNAGYDVLTWGQNRSFELGNGKQSAVPMPSYVQPFRTEPGSRFMVKETRKVIKDMEGKVRGRNVPVQETVVAGWGCTAVYWKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V1</accession>
    <name>M5G9V1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_47759</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631979.1">
        <property type="nucleotide sequence ID" value="XM_040774779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V1"/>
    <dbReference type="STRING" id="1858805.M5G9V1"/>
    <dbReference type="GeneID" id="63689841"/>
    <dbReference type="HOGENOM" id="CLU_109098_0_1_1"/>
    <dbReference type="OMA" id="KMEDQEY"/>
    <dbReference type="OrthoDB" id="274995at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="8">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="120" mass="13886" checksum="1DC455229EE479A6" modified="2013-05-29" version="1" fragment="single">KGGKNRRRGKNENEDEKRELVFREDGQEYAQVIKMLGNGRLEVQCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIVKYTADEARNLKAYGELPENAKINETETFGEEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA59</accession>
    <name>M5GA59_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromatin assembly factor 1 subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_78684</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629726.1">
        <property type="nucleotide sequence ID" value="XM_040776355.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5GA59"/>
    <dbReference type="GeneID" id="63691417"/>
    <dbReference type="HOGENOM" id="CLU_020445_3_1_1"/>
    <dbReference type="OMA" id="PHEEGCL"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059104">
        <property type="entry name" value="Beta-prop_EIPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23609">
        <property type="entry name" value="Beta-prop_EIPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="8">
        <location>
            <begin position="52"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="EIPR1-like beta-propeller" evidence="9">
        <location>
            <begin position="258"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="305"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="52066" checksum="159F38F2590BBCA4" modified="2013-05-29" version="1">MSARDTPNSSKSGGQARMEVEDDEEPHRPDVSLAGVAWDEPEQEDEHKLINEEYKVWKKNTPFLYDALVTHALDWPSLTCQWFPDKENPPNKPYTVQRLLLGTHSSNQAREYLQIVEVQFPKVLENGKSVLDSTDYDDEKGELGAHGSREARIRVTQKINHRHEVNRARYMPQNPDIIATQTTMGDIYIFDRTKHSNHPDADGECRPDIVLRGQTRESYGMSWNPLKKGHILSASYDTGVYEWDLQQYSKMSGNIESVRKYEAHSEQVEDVSWNRHNDYLFASVGDDKMLYIWDSRAPNKPIQDCVAHDQDVNAVDFNPASETLLLTGSADCSLALWDLRNIKTKLHSFEGHRGSVILAAWSPNYETVFASVGDDRRVNIWDVARIGEEQTPDDAEDGPPELVFMHGGHTSKISDFGWSPTTPWQLCSTADDNILQLWTPTSNVWAGEAVPIEIDELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAI5</accession>
    <name>M5GAI5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632753.1">
        <property type="nucleotide sequence ID" value="XM_040769718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAI5"/>
    <dbReference type="STRING" id="1858805.M5GAI5"/>
    <dbReference type="GeneID" id="63684780"/>
    <dbReference type="HOGENOM" id="CLU_417747_0_0_1"/>
    <dbReference type="OMA" id="ATHKEIF"/>
    <dbReference type="OrthoDB" id="2417614at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="2">
        <location>
            <begin position="467"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="657" mass="71435" checksum="6DE696275D1E2267" modified="2013-05-29" version="1" fragment="single">MASPAPSPTSPSPGKRRFHRLSQWLVKNGNKLLKDKPLPAPPERPGTPLREETHREIVTVTPSRREGERRPLSNQSEVAGEFGYDRKIDGRDYDLARTEKYAYGSVQGTDQNPQAWESGLPRMQKHGRSASHDPPAPGRPALNFSDGGSESAYPAYNLQGNEKGLATDYGDSAIPRTGRVVSAPPPRRVLDGAYIPTQYPPDTEPKVSSNRPAITIPPDIRTSPLYASSRTLQYALAGDESPSPASRTGQRMHIQMPVPMHALPLPDAFAALSLTTPTPRSAPPETLMQPPLGHGPSHSAVSLNVPSPVRPQQQQADGRTPPRTPVKHAGRRRSSSSPASPSLAALSTLSTTPNQPTGSSDSPASRQPKMTVQCAGITKSGLSCQRQVKALSALAFLAPDEPVERYCHQHAREVLEPSGFYTRPQAGGAPRWIAYGEWIPEYLSQPTQILLRTTMESPPSVSDQPGHIYAYELRTPASEPVALKVGRAGNVKNRLGEWGRQCGKEVVLRGLWPPAAGEREGNPSLMRGRLKPGEKAPCVHRLERLIHLELADVSLYSTHLRVDFFPSTRVVPSGTTTPARGTRSKASGTPAKGSLPSSPASASKNPLRRPLTACPECGKLHREIFTFDRVGSGRAKGREWEEIVRPVIDKWGRFVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAU6</accession>
    <name>M5GAU6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_65278</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629996.1">
        <property type="nucleotide sequence ID" value="XM_040775777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAU6"/>
    <dbReference type="STRING" id="1858805.M5GAU6"/>
    <dbReference type="GeneID" id="63690839"/>
    <dbReference type="HOGENOM" id="CLU_013173_4_3_1"/>
    <dbReference type="OMA" id="DVTCHEI"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000016">
        <property type="entry name" value="Protein phosphatase 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="412"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="492" mass="54617" checksum="A4F535653E2FA043" modified="2013-05-29" version="1">MGQTLSSPATEKTTDEGRDERFAYGVTEMQGWRITMEDAHTTVLNVDDVEGEEEKHPSERVSFFAVFDGHGGATVAKFAGKTVHTRLAEQEEYQNKDYRGALKYTFLRTDEALRADPMFRNDPSGCTAIACLVTPENKIWAANAGDSRAVLCDSGRVKPLSYDHKPNGTVEYARIMAAGGWVEYGRVNGNLALSRALGDFEYKKNLSLAPERQIVTSDPDIMSHEISEEDEFIVLACDGIWDCMSSQSVCDYVRRHVAHRMPLGKICESLVDYCIAPDADLEKSGIGCDNMTVIIIAILHGRTLEEWYDWIVDRVERGFAYPTPSEFKPLYGPRRGYSWDFTRSNTGRLAFDLRIPSSYVDDSSDEEMEESEIGHGMFRSAAKGKGEEVLGKGKGREVRDLDIEVAELEETYEWESDDSGEDATLPPGFTSTRLTSLGRPLVAGPPELKNLGAAHFKPEKQLVHTPEGDAPSPAVLVEGLMDTSEDPTKIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB35</accession>
    <name>M5GB35_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_103087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633033.1">
        <property type="nucleotide sequence ID" value="XM_040767709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB35"/>
    <dbReference type="STRING" id="1858805.M5GB35"/>
    <dbReference type="GeneID" id="63682771"/>
    <dbReference type="HOGENOM" id="CLU_130569_3_1_1"/>
    <dbReference type="OMA" id="VIQECIM"/>
    <dbReference type="OrthoDB" id="296187at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12398" checksum="47D0DF871714F5B9" modified="2013-05-29" version="1">MSDSKTLRNQLRIKTGVVNRLGKEHALYMKEAEENTRKVDTLVSSGTADEWDVKAAKRLQDESGRMIVDVRERLEKAADDLRDLVASTVGEPGVGESEEWANADKALELLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBN9</accession>
    <name>M5GBN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF1682-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_73834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633288.1">
        <property type="nucleotide sequence ID" value="XM_040776029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBN9"/>
    <dbReference type="STRING" id="1858805.M5GBN9"/>
    <dbReference type="GeneID" id="63691091"/>
    <dbReference type="HOGENOM" id="CLU_042570_1_0_1"/>
    <dbReference type="OMA" id="MHLVRDM"/>
    <dbReference type="OrthoDB" id="10039147at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="372" mass="42971" checksum="1236E12A60937BD8" modified="2013-05-29" version="1">MSAALLTQLNGALRFLQPPPPVPEGEYEGLEYRWRNIVFRPGQFKFEAVGLGFVIIYLLVWAIGRALNGGRVRAWFKTHLPFYETQFTRPAVRQLQSDGPSDYFIFSTGRRGVLSLHTTFTLLSRHNLIDMIYDFGRSLIELDYSPRDLLELDFRLNDDGTRPGFVWAVMKKDEMKTLRRARWDLSLTKAGDDKTLPVSLGIMTEAADITEAILKGPLLATLNDPNVLKYFRYLIVTDQPADRPEVPIPLAERERHVILALEPPSGGQNAETLPMVQSIFRFVDTVDKLPLRVETIRKLKRSRQDFEEELLKEIAKEKKERDEEEGEDKKAAKRKAEQERVSKLSAEEQKKWEEKERKRTMKKAQGKLVKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC37</accession>
    <name>M5GC37_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_105815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630546.1">
        <property type="nucleotide sequence ID" value="XM_040768146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC37"/>
    <dbReference type="STRING" id="1858805.M5GC37"/>
    <dbReference type="GeneID" id="63683208"/>
    <dbReference type="HOGENOM" id="CLU_011354_0_0_1"/>
    <dbReference type="OMA" id="GRTCCYS"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="747"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="747"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="797" mass="89256" checksum="0BB7B9710EEFFC2C" modified="2013-05-29" version="1">MLTHSTPSSTLPPLLGNRTRPDPMPIAFDKRSSEEEDAAERRGVRKRKRLSKACDACHKSKRRCDGRSPCANCEFATKTCVYTDSLGRAVAAPHARSEDLVSLLFPRPALASQLTSPLRSAPYPPQGVMGPRPIASGPLTRPSGGLPVNIMVDTPQMLKEEYPWAKTEELRKALTDVMPNTRITVDPTIKLELTNIFFNKCTPYNLMIHKPTFLSMLTNGSLPNYILLSIMALAAPYSSHPALRILSPNGRPWQQGEIFAEPARRVLLDRTGNVQLDYTLEVAQALIMLHVHEVSMRRSSGANGRYMTMALDILLRFETHRLDASGAMGETTEPTKALLAESYRRTFWLIYFIESLCSTFTERPLSFKESEFAVRLPMKDSRFEIFADAEPPTEFLRPGGQDVTEPGAFGYLVRITSIYVRIAALIIESQNIGMLRNTETHRRLTTQLQECERSLTDWQLSLPLRLRFNEANLRMHIHMYHIAGGFGWAFAYMHALSECCMLAIYEVFDEPPMTRSKQAIANLMIILDWLEPKGRSNIATAWILLALLQHYDRARVEPDARVQEWCHEYEAQYGIKLDDIRSPSFRQNWMGPRVHAPRLINGQGTPTWQAVGQPLSTSAAPRPSLHIGTTNHYDYPMGGGPAHTYGPTFPPPRTTHTPYNGITMDPLPTPATSHWPGDQTLGPLPSLPRIFDRQEVSAMHLSPVNQVSPYTMPYTDGYLSGPNALPHHHQYPSNHSFRIRTNGLPASSLDSLSGSTTDRFTSVSPADEHAQPAKRAPVGLGWLADEPRAERKVGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCZ9</accession>
    <name>M5GCZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631046.1">
        <property type="nucleotide sequence ID" value="XM_040772077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCZ9"/>
    <dbReference type="STRING" id="1858805.M5GCZ9"/>
    <dbReference type="GeneID" id="63687139"/>
    <dbReference type="HOGENOM" id="CLU_074846_2_1_1"/>
    <dbReference type="OMA" id="SFNERGM"/>
    <dbReference type="OrthoDB" id="10044044at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="18007" checksum="178C1480F04B933F" modified="2013-05-29" version="1">MNMSDSRWARVSDKLATFHGFLAAQLDATYDLADGTFQRRGMSLQTFISEVADFKRQLETHINTEARHIYPMLAQRMPAFTPGQRLSGAHGVVRRGVDGIESIIAKTTANPASYNGGELRQCIDSFRSTLYALFADELRELHPANMQRYWSLNEVIALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD72</accession>
    <name>M5GD72_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase/thiol ester dehydrase-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_45390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633534.1">
        <property type="nucleotide sequence ID" value="XM_040774642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD72"/>
    <dbReference type="STRING" id="1858805.M5GD72"/>
    <dbReference type="GeneID" id="63689704"/>
    <dbReference type="HOGENOM" id="CLU_1896143_0_0_1"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="134" mass="14648" checksum="781170B7647ED935" modified="2013-05-29" version="1">MTVTEDCLNGMGFLHGGCTAYLIDTCSSITLTALDPPDYSIPPTVSLNLNVTYHAAASLGASLRIISTVVSFSTRVQTVRCEVWDVTNPTHRLVASGMHIKMRSGKEGDPKAQEWRKEVYGEDMWATNAQKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA5</accession>
    <name>M5GDA5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_94618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629100.1">
        <property type="nucleotide sequence ID" value="XM_040777233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA5"/>
    <dbReference type="STRING" id="1858805.M5GDA5"/>
    <dbReference type="GeneID" id="63692295"/>
    <dbReference type="HOGENOM" id="CLU_008909_1_0_1"/>
    <dbReference type="OMA" id="WCGDDCL"/>
    <dbReference type="OrthoDB" id="1792at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.780:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="515"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="840" mass="94209" checksum="88B11DE231AFAC8E" modified="2013-05-29" version="1">MAPTDHPTSTWEPMQDGTVFYRKQELYSMQWKVQDLSDFKVVGARYGGPLAIIRDEHKVIALGGAQRFTKPQIQVYSSSGGLISTLSWDQGKIICMGWAYDERLVVLSEEGLYRVYDLQGEYEQFSLGAEALEEGVVEAQVHETGLVALTGSLNFLEVRSWEGGKAQTLASSGLSTPPHCWTIMPPELTVSRHVEVLISTDSTILMLDNLECIDQRVSRGPFTFLAPSPNGKALALLTAQNVLWVVSSDFQGELAESDLSLEGVSGPPKQMVWCGNDSLVLVWDALVLMMGPFGDALRYFYASPVHAIGEIDGTRIVGAEKCDFLQRVPSSTDAVFRPGSTSPAATLFDAMTHFERKSPKADENIRSIRPELVAAVDACIDAAAQEWEPYWQKKLLNAASFGRAFLDLYDPSEFVAVGQTLKVLNAARYYEIGIPITYTQYQHTSPEHLIARLTSRNLHLLALRVSSYLQIKADPVLKHWACAKIAQTKGISVSEKDDDDIVQTIVSKFKGQYGVSYADIARRAWQLGRTRLATRLLDHEPRAEDQVPLLLSMKEDRLALKKAIDSGDTDMVYHVLLTLKKRLNLGDFFRLLEDGGPELAPAASLLQVYARQQNRELLRDFYFQDDRRTESAILKLEEAAEANDVVDRTAAIRAAGKSFSEDKDRGFEARMMDEHSKLLILQQAFEKDADGRVEFIGLSINDTIYKCITTGQSKKAEKVRSDWRVPDKRFWYIKLHALTEARDWEGLDAFAKQKRSPIGYEAFVNHLVSKGFPNQAKNFVPRCDAKQRIDLYIKCGDWRAAGAECKERGDKNRLDQLRRMAPNGLVQRELDQIASTMNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDY0</accession>
    <name>M5GDY0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_32308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629687.1">
        <property type="nucleotide sequence ID" value="XM_040774356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDY0"/>
    <dbReference type="STRING" id="1858805.M5GDY0"/>
    <dbReference type="GeneID" id="63689418"/>
    <dbReference type="HOGENOM" id="CLU_2891973_0_0_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="63" mass="7210" checksum="D5DE27CD45EBE394" modified="2013-05-29" version="1" fragment="single">LAQMEAAYTSLLFHHTKFNSYHASRFAKDGLEHPRIVTLKGDHTVGLPIMRSLNEVYRQVTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFT0</accession>
    <name>M5GFT0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tom7-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_103509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633456.1">
        <property type="nucleotide sequence ID" value="XM_040767767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFT0"/>
    <dbReference type="STRING" id="1858805.M5GFT0"/>
    <dbReference type="GeneID" id="63682829"/>
    <dbReference type="HOGENOM" id="CLU_173610_1_1_1"/>
    <dbReference type="OMA" id="FILYLGW"/>
    <dbReference type="OrthoDB" id="284357at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012621">
        <property type="entry name" value="Tom7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34944">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34944:SF2">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08038">
        <property type="entry name" value="Tom7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="52" mass="5915" checksum="BB6FAEA14558F509" modified="2013-05-29" version="1">MPVSEETQERIQTLVEVGKTVLYYGWIPLIIYIGYTRSNPHPSLIQLVSPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFY3</accession>
    <name>M5GFY3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_92575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633571.1">
        <property type="nucleotide sequence ID" value="XM_040777087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFY3"/>
    <dbReference type="STRING" id="1858805.M5GFY3"/>
    <dbReference type="GeneID" id="63692149"/>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="OMA" id="YVRWLHG"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="126"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="574" mass="63597" checksum="DBA6E476835BF358" modified="2013-05-29" version="1">MDAAYAFPDAPVTHIGVRSLGDKESTPIDLSHHLSDMSNARIASPLKALMKYMAQPGMISMSGGLPHESYFPFEEISAQTAVPDTFSLTPEEKSSFSWLWNLFGAPTRKTKEVTIPKRAAGGDMEAVQLATALQYGQATGLPLLQKFINEFVQRVYRPINPLTTTLVHVGNTDGWAKAVLTLCNHGEGILVEEYTYPSAIASAWPIGVRPVPVKMDSEGMLANDLDHVLSGWDVEARGGMKKPHVMYTVPVGQNPCGTTMSEKRKKEIYAVCVKHDVIIVEDDPYYFLQCGTYVPKAQRTTAKVAKDGKDAEEAFIQSLAPSYLRVDYQGRVIRLDTFSKTIAPGSRLGFFTCNPMFAERLLRAGETSTQAPCGFGQALITSLLNGWGMSGWIRWLRGIRAQYTMRRDMCMDALYNHFDLREDLRASSIRAWDGAPVLVAHKKGAVAQEKYDSTTSLFSIVPPVAGMFLWIQVHVYNHPAYDDLVRSGMSESLASATLTFRLWKKLVDNKVLWSPGWFFATDGVQPDIGEMGFNPAVKAKGMEGCFRVAYSSASPEEMNKAMDVFAKQVVKFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG48</accession>
    <name>M5GG48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2 small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2A</fullName>
            <shortName evidence="5">MOCS2A</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfur carrier protein MOCS2A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_47816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaD family. MOCS2A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631757.1">
        <property type="nucleotide sequence ID" value="XM_040774786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG48"/>
    <dbReference type="STRING" id="1858805.M5GG48"/>
    <dbReference type="GeneID" id="63689848"/>
    <dbReference type="HOGENOM" id="CLU_114601_4_3_1"/>
    <dbReference type="OMA" id="IECNDEV"/>
    <dbReference type="OrthoDB" id="5595860at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03051">
        <property type="entry name" value="MOCS2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028887">
        <property type="entry name" value="MOCS2A_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="1-thioglycine; alternate" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycyl adenylate; alternate" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="104" mass="11344" checksum="F867D17395CD8498" modified="2013-05-29" version="1">MNIHEIQSAISASPRAITVLYFASARTTIDISYERIPLPEAGLPLKELPKLLEERHAGKGLGKVLERCRWSVNDEMVEHIGEGEDEVVLRGGEEVAVIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGC6</accession>
    <name>M5GGC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632147.1">
        <property type="nucleotide sequence ID" value="XM_040771672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGC6"/>
    <dbReference type="STRING" id="1858805.M5GGC6"/>
    <dbReference type="GeneID" id="63686734"/>
    <dbReference type="HOGENOM" id="CLU_008075_0_0_1"/>
    <dbReference type="OMA" id="WKRREHQ"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="925" mass="104673" checksum="43B6598ED2CD2A3D" modified="2013-05-29" version="1">MDPQEERQLKPIYAALETNSLKSALQHCNKLLKKKSNWDIVKALKALALQRGLKTEEASQLCDEILKNKPSDESTLLALNLTLRPLGRHEDIVTLYDDAFKKHPDNEEIGAQAFLAMIKVRSWKTAQQVGLKLWKTVKHDRYLYWYLMSVTQQASDPETPEQMSKILLSLAARYLATSDTPSWIVPDRFHLHLQVLLGLGDVTTARQLLESEKGEELCRNGLVLEDVRRGLAKRVGDWEGERLRCKKKVEAGDGNWNNYLAMLEGTFIVPEVPVANGETNGDAEKEKHEETKVELAALPPLQERIASAQALFTSLVAQVGRKERAPSLALLELEKRTRALEPLLTTGSPPRVDQMKVYLEKFSEKPCCFDDLKPFVEVLGEEELGKWIEHLKSWTPDVTTPQALETTLTIQKLLRHRQSTTGEPTAEQASSQASSQAFAFLKLYRDALPLGKDLKPVELQPADDFCFLAAQAFVGAWARDGQLKHLWQAVCVLEYGLVKSEKAYQLRLLLICLYRLLGASSLCLDHYRETNVRTVQHDTLSWLVLNRATTFSTCASGDISYLTECLEASAIYADNWTETGEMITKAFQYEKYSQIPDFLNFEELIENSLQRDLIRIEHLRMTLTHELLNNVEMLGIPQEIQDLDLNLQRKSNPDNRDFSVIPNMQPMGQEILKQVELGPKCMAPWVNVFSKIYLRSLRALSNVYNVPESFTASIKDKTEFTKAERAVMTLSDDLLEWLAPISALPVESDGKLTNGHANGVEAVSPVLLFQTEPTKESALEASKRVTQFFDDEWAELQKLVEANALPWELLHIVSIALEGFVLVDLFTYPFKVPSGRAKKGDPVFQSVKAVRQHAVDMLKKFSEELTRLSHECGSKPLAEFEGLCEPLVKEAEFRPDFVHKVGKKLLESRKKMMEGMAKGIVRRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGJ5</accession>
    <name>M5GGJ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nucleoporin Nup133/Nup155-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_98268</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin Nup133 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632492.1">
        <property type="nucleotide sequence ID" value="XM_040777517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGJ5"/>
    <dbReference type="STRING" id="1858805.M5GGJ5"/>
    <dbReference type="GeneID" id="63692579"/>
    <dbReference type="HOGENOM" id="CLU_008112_0_0_1"/>
    <dbReference type="OMA" id="HVATLLW"/>
    <dbReference type="OrthoDB" id="103454at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037624">
        <property type="entry name" value="Nup133-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405:SF11">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="8">
        <location>
            <begin position="725"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1159" mass="128932" checksum="843B3E59B5D9C843" modified="2013-05-29" version="1">MDVDEILPAAGEGRERDVRQMRDGEVERVLLKDDDYEVAVVGEVPGEVKTLLESINLQKEPVRGAIDDRTGFAFLTLFDRDARTHPPATAQVYTFPLPPARSGTLAHAALVPHQAREPGLLVVLPEGEARYWDSVTRALTSRDKFASVVLSLSEGEEVNGVWRWENAVFLLSTTLGNISRLMLTSTNMGRALVASSPFARPRGGLTRLFSRAQVPGSPAVVGLAVVPDPARGADVWIAKAKSVELWRLEREGGEHLVLEVNMQELLSTALPAQEDRSFWDVQLLDIAALKDGTPAVAFACTLTTPGYVWSSTKPPSYAVATLAHAGSSDLQVSSLRELQYSTPSTLPSADVSLTAPQGGTTVFVQFPDTVISFTLIPGSVFYEDIPLRDLSENRYLGHSTDSPVEGQMTCLTALSGLVSLTVNVPSVTAKAQMMLHGVNREEVANGRLKERIEHAVYYGGSSANPLSFDFRSPDIEGDLAAAIEEISTEIVSSSYKYKPVVADLDRQLEERLDTAKELIGFIDSNHLLSRLSVTARWKICMDGEKIAAAKQLWTLHEDELRENPRSVLSTVLSDAIDRISAKQQGDGAESGIRPFLQDKIGEIGNLPHGIGELVEQERHSADSLHRANITLEADSLVVTLLTAAQEYRSEHSVRYGISEFSSPVPVWTETKENIDLLYLLNERTKEDYRSVYEINLNNPPSNSSRAEIKNLQEQLKYHLLFVARTYFRVVRNCLSHFEHSQGEDSTEARNLQVQHVAQRKGIIMGLVNMGHGQAALDIAEEEKDWETLVDLCTDEELGATSALLESYILNHGEAFAFELYQRYYQTGKIYQLLHRNAREEVQLLDRFLQQSGYHRISWIHDITMGNFQLAAGALMVEGKASTKTIDRKTMLSLGKVSELAQHTAKIYKENNLAIAGRYDKGLEMVTVHETLAEELAENIALGHLAQPDIMADTIAERKAARLGTSALVDVFKAAVKHVMHGDILSIEDLVDVLTLKDNQRGEYKDYGTALKAFEQSEAEMPTARAQLTLEALWRRIYLHDNWRELKPSDDMSDVERQARLRGTAAYATLWATVDGLDPKYFLRPANCRRVPTDDECRARFENYTSQQVAVLQHALEQEIGQLEDIFTEEGPDSPRMGLEYLYDETFALLGLDKETRMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGP1</accession>
    <name>M5GGP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_104314</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040767904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGP1"/>
    <dbReference type="STRING" id="1858805.M5GGP1"/>
    <dbReference type="GeneID" id="63682966"/>
    <dbReference type="HOGENOM" id="CLU_078295_4_0_1"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000054">
        <property type="entry name" value="Putative histone H1.5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="6">
        <location>
            <begin position="51"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="17518" checksum="7EE3D11B669AD764" modified="2013-05-29" version="1">MARTKQTARQSVGGKAPRKQLTGKQAWKEVVKNRGNGDDDPKDKKPHRFRPGTVVLREIRRYQKFTQMLIHKLPFQRLVREIAQEIKNVPKGRGELDIRFQSSALQALQEAAEMYLVNLFEDTQLAAIHAKRVTIQMKDMQLTRRLRGDPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGU7</accession>
    <name>M5GGU7_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_44907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633002.1">
        <property type="nucleotide sequence ID" value="XM_040774613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGU7"/>
    <dbReference type="STRING" id="1858805.M5GGU7"/>
    <dbReference type="GeneID" id="63689675"/>
    <dbReference type="HOGENOM" id="CLU_027441_1_0_1"/>
    <dbReference type="OMA" id="INTGHED"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30249" checksum="6D38F0D5B9EE6D93" modified="2013-05-29" version="1" fragment="single">VTYFPLWADCSFWVAAIFTAGSAVWVINGFLLFLPLVQPSVPVYSTAAGALAFVGGTLFEAGGWLMLVEATNTGHEQMFVGPLSSYLRWRRPSEEELLESQAHSGDEADEKHGASSKAKFVWFAKPMWRDIGYLASFIQFIAATIFWVSTIVGLPGVIPTLFTDPPVVITDIFFWTPQVLGGFGFVVSSLLLMIETQRAWYLPNPLSIGWQVGFWNLVGAVGFLLCGAWGYLSLDVPWENFESTCATFWGSWAFLIGSAIQLYETLWREEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH42</accession>
    <name>M5GH42_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Urease accessory protein UreF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_86241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633477.1">
        <property type="nucleotide sequence ID" value="XM_040776767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH42"/>
    <dbReference type="STRING" id="1858805.M5GH42"/>
    <dbReference type="GeneID" id="63691829"/>
    <dbReference type="HOGENOM" id="CLU_049215_0_1_1"/>
    <dbReference type="OMA" id="WVGRHEK"/>
    <dbReference type="OrthoDB" id="2550922at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="277" mass="30374" checksum="5054C6991BD8DD7F" modified="2013-05-29" version="1">MDREVRIVSYILILLADSNLPTGSFVASSGLESYFKHGFGSPSSGIEATLEFVQNSLESYARSASGFVRDAHEVVVRFVDGERAVRLEDTLAKLGELDSLYEAMTLNHVARRASTAQGIALLTLYTKGFTNPYGLANDANSNSVVNMDNFVVEMKLRIRHGKLNGHLPICWAVLTATLGLPAERSIWLHLFLHARALLSASVRLNAIGPYASQQLLLHSVRPLVDEQVKRCAHLHTGLGEEMKDTADDGDALPASTWPLGEILAARHDLQHSRIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPK3</accession>
    <name>M5FPK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624026.1">
        <property type="nucleotide sequence ID" value="XM_040774082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPK3"/>
    <dbReference type="GeneID" id="63689144"/>
    <dbReference type="HOGENOM" id="CLU_1855216_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15534" checksum="3854018EBA2A64E4" modified="2013-05-29" version="1">MAYNRQKVQAAGTVFGRRLEIEHRAEDDQKAREGRAAMRKASLQALFDSAAESSRKTAHADAPTRPFKQRLVHWRGKAAYNREKRKEKLAEQGKKSWKGLKSGAKATGKFLRAHWKEILQITVVIARKCVSAHVGGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPT5</accession>
    <name>M5FPT5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_101788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625663.1">
        <property type="nucleotide sequence ID" value="XM_040767585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPT5"/>
    <dbReference type="STRING" id="1858805.M5FPT5"/>
    <dbReference type="GeneID" id="63682647"/>
    <dbReference type="HOGENOM" id="CLU_049344_1_1_1"/>
    <dbReference type="OMA" id="VKTWSSY"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="44"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="33156" checksum="1F455F50CCE3F48A" modified="2013-05-29" version="1">MAAFADKDFNAEQYQSYRPSYPDELYDTIYKYHEAGGAQWNLCVDLGCGTGQSARTTASRLASVIGVDPSEAMIESARKVPQGHAKGGSMKYVVAPSEKLEFLEDASVDMITAATSCQYFKFPETWDEIRRVLKPNGTVAFFSYTAFQLGSPLNALNTYIDHCINSSSAMGPYRSQPGHDIVHTFLDLIPSPGQGFNASAEQRIKYIGEQFPLLHIENRQPVIIKASLPWSAIDGWFRTASYAHNYAKAHPEDKQNPEGDIMARLVKELKAEAEKMGFHENLINVETPMALLLFRKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ95</accession>
    <name>M5FQ95_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624491.1">
        <property type="nucleotide sequence ID" value="XM_040773944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ95"/>
    <dbReference type="GeneID" id="63689006"/>
    <dbReference type="HOGENOM" id="CLU_1396271_0_0_1"/>
    <dbReference type="OrthoDB" id="3359404at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="21767" checksum="292C93E7F0B2C8F8" modified="2013-05-29" version="1">MPRMPLRPQSILIPRVPTKSFPRLGRHSSSNSSSSSSSSSTSSSTSSSHPPPNDHEIPFRELTGSERHRFFWISILPTWGPIVVIGSAVFLTMQMTRAHLAHERFKGEILTEIRALEAELRTFHETSAARVLAELEAQEEEARVVFAGVAKYGKHWSGLTDSSPEAGAAQPKEGEDQSKINTARFRAWWSRFQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQX5</accession>
    <name>M5FQX5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Noc2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_59626</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624082.1">
        <property type="nucleotide sequence ID" value="XM_040775574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQX5"/>
    <dbReference type="STRING" id="1858805.M5FQX5"/>
    <dbReference type="GeneID" id="63690636"/>
    <dbReference type="HOGENOM" id="CLU_011272_0_0_1"/>
    <dbReference type="OMA" id="GCLRYYL"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="708" mass="80516" checksum="8364E2792B190530" modified="2013-05-29" version="1">MAKTAKATKRFISSGKLKQQIEQRHNHKKVKQQIEKRRGKGKRAEEKKTAKAVDEDKAQEAEDNDHRPNEMTVDDLLGGEFMDDGDSEEEDDNSSAVDDNESFASVDDLDADEEAHKMDLERLKEVDPEFYKYLQENDKELLEFGNEPEEMKDAEDVDVEVDEAEIAMEEEEDEIAVPSTAKEVTKEMLRAWQRSILEHHSLRSLRGLLLAFRAAVHMNEEDGTQYAYSIGSSAVYNKLVVTALKYTSIVLSHHLPYKTLPDGRYKPPAQTKKYSTLQKMILSFFSNVLHLLSQLPDGDMKLLVLSESTKVIPYIVSSRKVVKDYLKQLLDVWSSGFDDVRLTALLAIRRLAASPDQSILDICLKGTYVSLVRSSRVTTVHTLPSINLMKNSAMELYILDHEAAYQHAFRYIRQLAVHLRESMKVKSKEAYKAVYNWQYVHSLDFWAGVLAKACDRDALGESALHPLIYPLVQVTIGAIKLIPTPRYFPLHLHCVRSLLHLIRHTGVFIPLSPFILQILTSSEFSHKPKPSTQRPLDLEAFIRVPAPYVRTRLYQDALAEESAYLLGEWFETCAQSIAFPELAVPVTILVRRMLKRSSSVKLATTLKPLVERLEEHAKWVEKRRLGVVFGPADTAEVERFEAAIGVPESPLGKWVKLQRRARERRKAVIEKVSNIQTAWLDAHWKIGERGCIGDGGQLGKRALVKVMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR77</accession>
    <name>M5FR77_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_118878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625021.1">
        <property type="nucleotide sequence ID" value="XM_040770680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR77"/>
    <dbReference type="STRING" id="1858805.M5FR77"/>
    <dbReference type="GeneID" id="63685742"/>
    <dbReference type="HOGENOM" id="CLU_076393_0_0_1"/>
    <dbReference type="OrthoDB" id="2803071at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="39888" checksum="C2C79FEFD966B73B" modified="2013-05-29" version="1">MSPYFSRQKIERAIAERNADRIIAERNPLREGTLLNGTRASGLFDQEVSPIDVDAALAVLPYRPPFRPRLILDEEDESISLSLTRGLQTGKDRWAQVWLASVHIPRTTEHPQVVVKLLQEAFFPHPGDDIDDDDYVTEGASLHTPIGICRNEAWAFTQLRPLQGLLLPHSYGFYHLELPCGQNVIGHVMEYVEGHALKRDYQGMIDGSFYSAERRSESRAAVVQLAFNVYCLHLCDVHHGDVSPNNVLQIPGKLPFFVFLDFARASAYSDIMFGTMDGCGLWTCSEELELGETFCPWMEDALVKHEPWALSILGDLSLTRQLKHTIPGAERDYEAQAMRLKKSQDEKGQNEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRC6</accession>
    <name>M5FRC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_29360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624407.1">
        <property type="nucleotide sequence ID" value="XM_040774314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRC6"/>
    <dbReference type="STRING" id="1858805.M5FRC6"/>
    <dbReference type="GeneID" id="63689376"/>
    <dbReference type="HOGENOM" id="CLU_041217_9_8_1"/>
    <dbReference type="OMA" id="HERERSW"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="19325" checksum="3A4C5400A6AB2A57" modified="2013-05-29" version="1" fragment="single">RKRRICVLGSRQVGKSALVVQYVEHHFLPKYYPTIESTFHAPLQYHSHPYLLEIVDTAGQDEYSMLASRYAIGVHGFVLVYSVASRPSFEMIRGLHDKIMAYYGERAEVPCVIVGQKQDLVEQKLATRQVTPQEGQALAKEIHASWIETSACSNLNVSKVFDMLLEDVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSA9</accession>
    <name>M5FSA9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24598</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624957.1">
        <property type="nucleotide sequence ID" value="XM_040773754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSA9"/>
    <dbReference type="STRING" id="1858805.M5FSA9"/>
    <dbReference type="GeneID" id="63688816"/>
    <dbReference type="HOGENOM" id="CLU_011106_4_1_1"/>
    <dbReference type="OMA" id="RTQGFNH"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="221"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="164"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="488"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="539"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="564"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="666"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="701"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="710" mass="78684" checksum="BA58F580C5C9925B" modified="2013-05-29" version="1">MGVKVTKKPTPTGASGSGPHLKKVKGENFYRDAKAAKRAKVLTGGKAVRDRNGKIIEAAAYQKTEAETEPGRVAPDKRWFGNTRVISQDALTHFRNALSDKARDPFSVVMRRNKLPLSLLATDANPGTTQRPKIVEVEPFGETFGPKAQRKRVHVDVGSFEELAASAAGPSTQPAEGDEEEAPAEGTVPAPADPEEVAPENEYKDLPSHPLFAKGTSRRIHGELHKVIDSSDVLVHVLDARDPKGTMCEAVMDFIKKERAHKQVVFIMNKCDLVPSWVVARWLSHLSQIAPTLAFHASLHHSFGKGSLIQLLRQFQNLHSDKKQISVGFIGYPNVGKSSIINCLKKNKVCTVAPIPGETKVWQYITLTKKIYLIDCPGIVPISKNDSETDTVLKGVIRLSALPNPSEYVPELLGRVRPEYLGRTYGVNASWTWGKEGELEGVPVDIEATDLWLEKLARKTGKLLKGGEPDRDTVARMVLGDWQRGKLPYYTKPPVNDKDRQKDKERAEAKEKAKVDKKEKKLLGVQQDIRVLKFPNGTKWLDVDEKGDGDDVAVPEVVGAEGSQVDDDEEDEDEDEDEDEDAADDDEVDDDEDEGEHEDEDEDESGESVDEDAEVSEMTWEEAMSTLAGPTDELTKTALSSSSSPSKSRKRPVQEEDDGPEEVRPKKAPRMTTNKKKATNFFSTANVKNKNRSKRIAKPGQENERGRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSB5</accession>
    <name>M5FSB5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sas10 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_110601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="1924577at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sas10_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF8">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF09368">
        <property type="entry name" value="Sas10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sas10 C-terminal" evidence="6">
        <location>
            <begin position="587"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
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        <location>
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            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="451"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="156"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="458"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="565"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010979"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="663" mass="74689" checksum="789461206F3C3C58" modified="2013-05-29" version="1">MAQRKVKSGGLEKKEPSKEIDRRKSKIRAPVTHEDLGLDEEETWHKDKDKILLENDRVDEDTEDEEVFALKGISDCEDEGDLEEEEAEEDQDEELAAPPPRKSAKSKSNAKSTVQDAGLSSESEDEDESEEETWGTKKSAYYTVPGEDEETEDEEARALETAEAKRLQRKAREGLEEDDFGLGGVEDELEEVDAAMEEPAPVEKKQELPKDKEGLKRHLELHSPETLALAREWGDIVYRIGEIKKLIENQPADTEPDLLGIMHSHYQVLLTYATTLAFYLHLRATPSHATSPSPLSDHPVLDRLLELKQFLHVMESYNFAADDPLRTGELEDEDDEEGMDGVWDLKKRMGLEDGELEALLKETRGVEKELAEEEEPVMTNGKVKAKSKADGKPKSNGKEKKPVKEKKKGVSFDLVQPEFVPSARKRPSASVPADASADDLAYGEVTTLTAADLADKAARKRSLRFHTSRIESAAARRDAARRNREGGDEDIPYKARRKEVELQANARAEARLKKRQEQEGAELDDEEWGESDRKRAREAMQPGEEEDYEGLYEAVERGRKRRKLEKKEAYDEERAAERFIPDEEGPNGPRSLTRAILTNRGLAPKRSKLARNPRVKKRVKFEKAQKKLASQKAVFRGGQAALAGDYSGEKSGISKRLVKSVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSC0</accession>
    <name>M5FSC0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Terpene synthase</fullName>
            <ecNumber evidence="6">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_81212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776497.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63691559"/>
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    <dbReference type="OMA" id="RFIHTMD"/>
    <dbReference type="OrthoDB" id="2861623at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="38207" checksum="1BD800071C61DA13" modified="2013-05-29" version="1">MSSSPITANRPRTLILPDLVSYCSFDLAINEGCEVCSADSIEWIASFGDLSEKQRASMASIKLGTLAAMSWPSCDIHGLRIGADFMNYVFWLDDYTDGLQHTEALRVREVVVDILRQPEAHCEQGRSGSALEKLTYDIWMRMLPQCGEGTKTRFIEANHLFLQAVYGQSVLCIGGELSLLDGYIMLRRDDGGAKPMFVLIEYALGWELPSELVDDPVIKRLEDEANDMIVWSNDIFSFKKEQARGDRNNLITIVMEEKGLSMQEAFDFVGDMWKARFHDFKEDRKKLPSWGEVVNRQVEGYVQGLADWVVGNIHWSFASKRYFESERDFLGAHVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSR7</accession>
    <name>M5FSR7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625886.1">
        <property type="nucleotide sequence ID" value="XM_040773542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSR7"/>
    <dbReference type="STRING" id="1858805.M5FSR7"/>
    <dbReference type="GeneID" id="63688604"/>
    <dbReference type="HOGENOM" id="CLU_036838_9_2_1"/>
    <dbReference type="OMA" id="RNVVSMF"/>
    <dbReference type="OrthoDB" id="5783963at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="402" mass="44083" checksum="A5165B451407594A" modified="2013-05-29" version="1">MRRDVDAPGPTNSVTHVDMVAHKIIFDTDADLEKPGVDDVIALLLLLASPEIRLEAITVTFGNSTLQNTFSNVLKVYGLVQQHILEHPHDATRFPNYARPTVLAKGRAGPIAGELHIAEYFHGPDGLSDISNTHPHFGAVTTHSSLTVATTEAYKVILDILEREPPGTVTILAAGPLTNIALALREQPEIVMKARRIVAMGGALDVPGNTSPVAEFNFYADPYAAQEVIQFPQLPLFLLPLDITVPHSVDFPILIPAHHDCSPSHTPLQSFITAILTRPRNVMRMLGEDDAFQMHDPLAAWFVIQHADIQGTALVPGWKAHRRMFRLERIGELTKGMCVVDRRGTREVFHSNRAESGVEEAVALRNLAQEGEDGIMVIVETPGVKELTDALLDRVILNSRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTA4</accession>
    <name>M5FTA4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626156.1">
        <property type="nucleotide sequence ID" value="XM_040768977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTA4"/>
    <dbReference type="GeneID" id="63684039"/>
    <dbReference type="HOGENOM" id="CLU_912226_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="32368" checksum="0B35370762863BA4" modified="2013-05-29" version="1">MYTSAEHERNSVTADVMKGTKSIASSLGILCLMIAGIHGLVIPASPEQAASTNLVHSGGNSGEEMHAEVQCQGPFCDYVIPKADSTNAEELHVETQCQGPFCDYVIPKADSTNAEDLHAETQCQGPFCDYVIPKADSTNAEDLHAERQCQGPLCDSNAEELHVETQCQGPLCDSNAEELHAETQCQGPFCDSVIPRADSTNALDETADETKDAAGTTEDPISQAPMHASAEDKLMVHDETGCQGPHCDFVVRNKKAINSADNGTVDAADIGTLESKHNPDLAAETNQSENNVGAKDAPARSEDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTA9</accession>
    <name>M5FTA9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627748.1">
        <property type="nucleotide sequence ID" value="XM_040773128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTA9"/>
    <dbReference type="GeneID" id="63688190"/>
    <dbReference type="HOGENOM" id="CLU_2250042_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="104" mass="11354" checksum="A2A1A736A3BAEE1E" modified="2013-05-29" version="1">MYYHDASISAAHAEPFFLHHPTGPSSAAQKLPEPVAHAPVSVMGWFDPPITHIFPFRARSVSLQPSRSQRRPPICLPILSHPLNPCAPGCLPLTPFLISQGRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTB5</accession>
    <name>M5FTB5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627758.1">
        <property type="nucleotide sequence ID" value="XM_040772933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTB5"/>
    <dbReference type="STRING" id="1858805.M5FTB5"/>
    <dbReference type="GeneID" id="63687995"/>
    <dbReference type="HOGENOM" id="CLU_083919_0_0_1"/>
    <dbReference type="OMA" id="NRVWIDP"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="5">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="22472" checksum="A092D8B228A2F16F" modified="2013-05-29" version="1">MVNLRSQKRLAASVAGVGKRKIWLDPAEQSEIGNANSRSHIKKLIKDGRVIIKPTVIHSRARTQDLLAAKRKGRHTGPGKRKGTAEARMPTKVLWMRRQRVLRRLLRKYREAGKIDKHLYHQLYQKSKGNVFKNKRVLMEYIHRAKAEKSRTKLLNDQAEARRVKNKAARERRVARIAEKRAEMFSVEETPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTF1</accession>
    <name>M5FTF1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795892">
        <property type="protein sequence ID" value="EJT96521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623419.1">
        <property type="nucleotide sequence ID" value="XM_040771438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTF1"/>
    <dbReference type="STRING" id="1858805.M5FTF1"/>
    <dbReference type="GeneID" id="63686500"/>
    <dbReference type="HOGENOM" id="CLU_131613_0_0_1"/>
    <dbReference type="OMA" id="QYEDMAH"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="174" mass="20136" checksum="2D495D3FBB061E08" modified="2013-05-29" version="1">MSYESEEFSEAPSDQLFSGTPSVKDTLASNATNGSALQQQYEDMAHLYAESQLMIKTLEKQLEHCEADLQANQQLVATLENELHDAERHLRKSRVQSSDLAKERDALNAQMQALQTQLRDAQDDSTRLRRSMQEEKQASERKLEEERKARERARALLDQRMEDMQKRKSKFVCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTH8</accession>
    <name>M5FTH8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_102861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623449.1">
        <property type="nucleotide sequence ID" value="XM_040767679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTH8"/>
    <dbReference type="GeneID" id="63682741"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_2_1"/>
    <dbReference type="OMA" id="ILASMEM"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="240" mass="25760" checksum="520AE0819C26FADB" modified="2013-05-29" version="1">MSLTYLITGAGRGIGMSFVKALLACDTTMLIFAGVRNIATATELRTIAQSDKRVIVIPLDMDDDGSIQNAARIVSSRAKSLSVLINNAGFTPETMSPAAYVPPGDFIQAFKTNTLGPILLIQSFLPLLERAGGLVINISSILASMEMNPGRQVAYSVSKAGLNMATTIFQKQVKDNIVKFIAVHPGVVTKEVRPDPRQPQAPYITSDQSAQGILQNIVFSASVASMCGRFVSWDGKNIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTP6</accession>
    <name>M5FTP6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_24346</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the creA/MIG C2H2-type zinc-finger protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625692.1">
        <property type="nucleotide sequence ID" value="XM_040773649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTP6"/>
    <dbReference type="STRING" id="1858805.M5FTP6"/>
    <dbReference type="GeneID" id="63688711"/>
    <dbReference type="HOGENOM" id="CLU_490028_0_0_1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000089">
        <property type="entry name" value="DNA-binding protein creA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000152">
        <property type="entry name" value="DNA-binding protein creA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF1">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="77"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="266"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="333"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT98794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="556" mass="60282" checksum="3613BE97691CAE6C" modified="2013-05-29" version="1">MELGKDTPAETNGADAGITDKSKIPRPYKCPMCDRAFYRLEHQTRHVRTHTGEKPHACTHPGCEKRFSRSDELTRHIRIHTNPARRGARKAKSNPNSDDEGDPMHSRQHSPTWHDTFDSHDDMCYPASAQISRGPSPPPGAYHMQHPHGGPPSSVITYRHNNTHYGGYDHYGGHGQLNRVPSHMDTLALAASEQLYHLERAEAARRAAFEIKRSPQVGTAAPVSSERFTALNRRSVTSRSHDDLARYNRDIGGFGLPPPVGYHNSTAYEYTSSGPSSAYPHQKASSHSPPASLSPESAYREPAYPGSAHYTPSSSPTSGSAWGAAHYNRMLPPLSGSVSSGPSPAPSRHTSRATSPVGWGFSKMALTDRDREPEGHSASAERGPHAHHTLHRHSMRTAPYTVPVIEPSRLRKSKSGEQLQYEYTQSHGSGILTPSTTSSSASSPYNANYVVAPVSATTAPTSPVSSRPPSPTRGYHHSHKSHARDFGMTPIHTATSSARTTPPGGEPEGLIQLPPLHIGENHGSPVALPSFREMENLGMDVDTPPAITPPAIAAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTW7</accession>
    <name>M5FTW7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vanillyl-alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_56472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625807.1">
        <property type="nucleotide sequence ID" value="XM_040775375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTW7"/>
    <dbReference type="STRING" id="1858805.M5FTW7"/>
    <dbReference type="GeneID" id="63690437"/>
    <dbReference type="HOGENOM" id="CLU_024402_0_0_1"/>
    <dbReference type="OMA" id="FNDNAQM"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF114">
        <property type="entry name" value="ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="107"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="608" mass="67244" checksum="E66ABAF356CF6FF8" modified="2013-05-29" version="1">METTLTPTPTTQESHSGIPPSLIPLAEESKLLLHSTSTPLGRTSAAREEPLPVLPPDVDRPTFNAAIQELREGLGEEWVVLNTEELDDGWYMEHPNTHDAHHVFPPWDLVSSGVCYPSSTADVQLIVRWANKYLIPIHPISLGRNFGYGGAAPRVRGSLIIDLGKRMNRVLKLDGENCSALLEPGVTYFSLWETIRASGLDLWVDVPDLGGGSVLGNACDRGVGYTPYGDHWANHCGLEVVLPTGEIVRTGMGALPGKEGEDNPTWQSFQYGYGPFLDGIFSQSNYGIVTTMGVWLMPATQHTSYMLTFAEEESYPEIMSLIRPLAINKVLGNVPQLRHAIQELTITGLSRASIWDQPGSVPPEVVRKEVAKLPCGECSWVFYGTVYGPAAFRAQQLKTIKRQFFQLPGTRLFLPSDVPSTHYLHSRALVCSGQPVLRELNWLAWVPNGAHVAFSPICPTGGEHVKKLYEMCKRRCKEFGLDFFPTLCVASREAHVIVELVYDKSSPSSKHAAYTCIRTLIADAARAGYGEYRTHLVFSDQVAGTYNWNGGALMKLNERLKDALDPRGVLSPGRNGIWPRRFRDKGWEMGEGDGRECSTQGVGMKFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU19</accession>
    <name>M5FU19_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623594.1">
        <property type="nucleotide sequence ID" value="XM_040770890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU19"/>
    <dbReference type="STRING" id="1858805.M5FU19"/>
    <dbReference type="GeneID" id="63685952"/>
    <dbReference type="HOGENOM" id="CLU_411613_0_0_1"/>
    <dbReference type="OMA" id="PPTTNFH"/>
    <dbReference type="OrthoDB" id="412109at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="667" mass="75146" checksum="B09277B53B09615A" modified="2013-05-29" version="1">MASVAARLPPGAYDQHLAAMKQRYSPASQSQQPPPIPTIPRELGGIQFEVSDLFKEQWEKYWQAEQERKRRLQGEWQAYEAQKLARSLPKHVAPRPPERPAVAVFDPKVSEQRAATKKKEEEERVKREVQQRFEAFTARLAQERAQGSSPRAGTRTSSHQRSTSAVPNASPPPSTSSSSRSTPYTFVPQSSSSTFYPHTGQPPPRTPPPTSSHKPPPPSPPPSGTYQSPPRSQPIHAYRYNFPDTPPSSPENSPPKHSHRYWDPFTGAQRDTPYPNFGSKNAGPDSPPPSPSPSNTSNEEDLLGANYRAPQPSPIPIRTPHPTPPHSQEHARHRTAPTRPPSPVRPKVWSPPTPSRQSSQRARPTANEPDLEASARAYAEARAQAEADTKRRAQEEEAEKEKENRRKQEEWMKNQEEIRKQAERVAEEKARREKEWEEKFKKEQEQFSERARQQQQQQQQRSSSQSSKQRPQPQQQQQQQQQGPRSSAGTGQHQSWGQPPPGAGPQPQSKYAPPPRPPPPGAGPQPQAKSAPPPRQPPPMSTTTPSANQTIPILWLSYETRWQELIKSPPTSLTLYSIPFPVVQLRSAADINPQTVSQFLLSPQHSPEKSHKGRLKDAMLRWHPDKFEQKWLTRVPESQRATVREYAHAVAKSVTALMERERNGTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU31</accession>
    <name>M5FU31_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_97509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623619.1">
        <property type="nucleotide sequence ID" value="XM_040777461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU31"/>
    <dbReference type="GeneID" id="63692523"/>
    <dbReference type="HOGENOM" id="CLU_1635332_0_0_1"/>
    <dbReference type="OrthoDB" id="10634214at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="162" mass="17471" checksum="9048DE2C483194DE" modified="2013-05-29" version="1">MDNRNGTVTTGTDQKRDQTVAIVIVLMAGLSLLVSSLLFVRRYHSRQQMLASRFPSAPFGPPVRQPSYYTSQLEAGGAPPLLLPAQLQLPRVSRWPEGANPETGEQLPEYKVAAKSPVVLTYPEMVYTGTGRAGMGEPPPYDASLGESGREDAGEPSARRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUE9</accession>
    <name>M5FUE9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_85260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623759.1">
        <property type="nucleotide sequence ID" value="XM_040776726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUE9"/>
    <dbReference type="STRING" id="1858805.M5FUE9"/>
    <dbReference type="GeneID" id="63691788"/>
    <dbReference type="HOGENOM" id="CLU_1209798_0_0_1"/>
    <dbReference type="OMA" id="PSECIQR"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="1">
        <location>
            <begin position="87"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="229" mass="25061" checksum="6C00CC0377EFBEAC" modified="2013-05-29" version="1">MFRMLQQPLLWPTAGSALKEAIDGNGHPLLLLHAAGTRVADLERQAVSCNDAPKPPLYVPPTNEQLVDEILGVSKEVTRFAFSVLTTEPDAQCHYWPVTPPERFTGPWNHTLRNPTLVLSNTADPVTPIASARLVKELLGDSAALLLQNGPGHVTSSVPTLCTINKIRAYFTDGVIPDENEICQLDEALFPGSEHQLGKYTEDERTKLEAAETLHALMMDSDLSAFQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV32</accession>
    <name>M5FV32_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626342.1">
        <property type="nucleotide sequence ID" value="XM_040773489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV32"/>
    <dbReference type="STRING" id="1858805.M5FV32"/>
    <dbReference type="GeneID" id="63688551"/>
    <dbReference type="HOGENOM" id="CLU_101473_1_0_1"/>
    <dbReference type="OMA" id="VWEGYRA"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="100" mass="11656" checksum="5BF021D864358752" modified="2013-05-29" version="1">MSHSLKPECTPLKHKYDACFNTWFEGYLQPPPGGKSESEEAQRQWQRDKRDEYERTCGKVWEGYRAYLDGALTEKGLDDLLQQAREENPLIEAEPAEARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVI7</accession>
    <name>M5FVI7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Puf family RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_82038</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626522.1">
        <property type="nucleotide sequence ID" value="XM_040776548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVI7"/>
    <dbReference type="STRING" id="1858805.M5FVI7"/>
    <dbReference type="GeneID" id="63691610"/>
    <dbReference type="HOGENOM" id="CLU_013994_2_0_1"/>
    <dbReference type="OMA" id="YGPEFSI"/>
    <dbReference type="OrthoDB" id="497380at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="4">
        <location>
            <begin position="8"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="585" mass="65334" checksum="558F3A98FE682FB0" modified="2013-05-29" version="1">MAVDGEEMDDEELSQLRTMTKQDKLAKKEDRKARKAAKPNADLTANAKHLWSLARKTEISKDERTKHVKALMEAIRGHVKEIVFKHDTSRIVQTLAKYGGSEERNEIAAELKGSYSELATSKYSKFLVTKLIRYCPMHRASILQEFQKDVIRLLLHREASQVVADAYELYCNPAERALLLRDFYGKEVALFDSQKLGKGGLKSVLEGSTVERRRRVLSAVQENLMTIFNNPDKGAASLSIVHKATWEYLSELCGLPDEAEQERLRREVFDNCQELLAEFVHTKDGSRVVREFLARGTAKDRKVIMKTLKPHIEKICKDEEAQLVLLTALDVVDDTKLLAKSIVSDITDLAPSLSFDKHKLGRRVLLYLLVPRSPRHFPPPTLALLSETDAVSTKTSKKDPQVRRDEVRKAASGDLISCVASKGVEMMKDPGASLVVTEIMLFADGDKSTATETLLRPIRDATQDENWAELTELINHPHVSRLYKTLIQGGHYEKESMRVDEPSSWSGDDFAVAFFEAAGGHQKGEALVSMGSGSGAFLVAELANRLKGKPAGKKLAEIFTSEVLRELNEKDVKGRGVLLEKLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVT0</accession>
    <name>M5FVT0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624369.1">
        <property type="nucleotide sequence ID" value="XM_040769326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVT0"/>
    <dbReference type="GeneID" id="63684388"/>
    <dbReference type="HOGENOM" id="CLU_709847_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="44212" checksum="1B0DD454D0EC1DB2" modified="2013-05-29" version="1">MYTRDIQPIDLDKRDGAKDVLCLAIKSRDWDIKAQLDAIEAVVAVVYPGSLWTAKQVEEQGMNNIVYLATQVQGQKSLPHKLASLDRVIVRIAHKRNHDTPKDFEAEIAAMRHVYCHTQIPVPKVLAYSIDDHISVMEFISEGMRLNRAWPKLTPMARKQTVRDYARIISELHKVDGYKGIGSLQIESGCGLTPLRPPSLPNSDPSTKPLETTFKNAETLLKTVLQTRSDYLKQADPNDRKGLPYWADLKDAQEVYEALLERLPRICRPVDDCPRMCLRALCLRGISRNIIVRPSDGTIVAVIDWEKVNILPAALLSWLPLFLTEGLSKTESVAAVQAYRQIIKETDPDLLVYFDPSYDDFREVAWVAAMDVWYNMETREIMSIVQRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVU1</accession>
    <name>M5FVU1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624379.1">
        <property type="nucleotide sequence ID" value="XM_040770733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVU1"/>
    <dbReference type="GeneID" id="63685795"/>
    <dbReference type="HOGENOM" id="CLU_1366219_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="200" mass="21876" checksum="96B04CA3D1955B7C" modified="2013-05-29" version="1">MSNSAGPDYWKQEVDPNPRDRANGPLKGPFSASPRFSRFRPPPTASIAAPMDEIGSPPSRLPGLPRSASAEKETREERPIADDGSDVELAACLRVQFPRPASPNPKTRPYPNPDRRLDRRNRRVLAHASAPRAVRREGLSAATRSALAHVGDPFLSQHERSSFLSRTWLPFLPQAGCAHREERGCIGSVPFGTVQIAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVX0</accession>
    <name>M5FVX0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628893.1">
        <property type="nucleotide sequence ID" value="XM_040767436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVX0"/>
    <dbReference type="GeneID" id="63682498"/>
    <dbReference type="HOGENOM" id="CLU_1045926_0_0_1"/>
    <dbReference type="OrthoDB" id="3361190at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="266" mass="29035" checksum="C508D551ADFFDB98" modified="2013-05-29" version="1">MYLDSHHIRRPMTTSPPAYTSSSPSISASHRPSLSLHDIPSDTDLPIIDGYTPAPSEPLPRYPRAAQYVFLSLDVGNSVVVDAHTGQPVMESLTTSEDGESSETQLRALTSNGDLICRVSWPSGRKAKAGPTLDWGSGQGAVGLRKWMARKGDPGALLRVKHRGKKYDVFQAGQALGVRYAQKRGREPMLLGIRDPMKYTELVLSPLVGEERGELLELGCVIVLLLKSKKKLGPDFEGRQLRDTIWSGVEKCFTSTGNAQPGRVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW95</accession>
    <name>M5FW95_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_95772</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626847.1">
        <property type="nucleotide sequence ID" value="XM_040777317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW95"/>
    <dbReference type="STRING" id="1858805.M5FW95"/>
    <dbReference type="GeneID" id="63692379"/>
    <dbReference type="HOGENOM" id="CLU_027221_0_0_1"/>
    <dbReference type="OMA" id="WSLHRFI"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000042">
        <property type="entry name" value="Vacuolar targeting protein Atg24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="13">
        <location>
            <begin position="63"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT99949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="472" mass="53714" checksum="252EBCBC626C2765" modified="2013-05-29" version="1">MEADSDFQSVHWDNTPGVEADAQLGFSSTHTFKPTTAVSPGFRTDYEHTADDADPTVPKWDGYLVVQVLDPVKELEGTKDMYISYAVKSQTDFPFFPQQQTVVRRRFHDFVFLWQHLSQDFAACVVPPLPSKHRAEYVTGDRFSPSFVEKRRLDLQRFLQRISNNPTLSRSTLLRSFLCSTEWSVSMHQAVAHAPDPDGKSSFFDSVTDTLVNSFSRIRKADERFVEMKEGIDRFEEGTGAVDRLWSRARTRQTDLATDYHDLAVAVQGLGFLESGITEQLNHFANTLLEFSSLIKHNVNRTQDPFLSHLHSLQAYTAASRALLKLRDQKQLDLEDTSEYLSSAQQERDRLAAIREGHPGARPGGLGAVGGYLRERVDALRGLDDDRARVERMRKLDAKIKDLQAEVKKVHDLSEAFNDETLREQAIFQAAKQDEMKEMLGKVADGNIEMYQQAIEEWDAIIPMLQRIRVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWJ7</accession>
    <name>M5FWJ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_91270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624684.1">
        <property type="nucleotide sequence ID" value="XM_040777002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWJ7"/>
    <dbReference type="STRING" id="1858805.M5FWJ7"/>
    <dbReference type="GeneID" id="63692064"/>
    <dbReference type="HOGENOM" id="CLU_024072_3_1_1"/>
    <dbReference type="OMA" id="CWHLNGD"/>
    <dbReference type="OrthoDB" id="308690at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990810">
        <property type="term" value="P:microtubule anchoring at mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="503" mass="55060" checksum="B19BC6052DB296FE" modified="2013-05-29" version="1">MDFTDLYKHASQLCAFSPSGSHILTATYDRLIIRLASTLQIMRTWEIDPAPSPSSQILKAKPTPSGRNNAPSSNGTKSGGITAIGWSEDEEYVLACLAGRGVVEVRSAREGEGEETWEAGIEAGAEGLVRAEFALDARNILCWSEWGLRLTIHSLISGQSTVIPQPTYPDRAYAFSLDAGWLVLATRKGGKDFLNVHDPLERFALVRQSPLPTTSLVDFSLSPDGLYVACWESLLDFKLHILALDGRLQATFTPPGPFAETGLGVRCVSWHPNSGFVAVGGWDDKLHILAKLADWRAVATLEMSVKLGADSGINAWREPSGWLEATMHRGFVQYSPAFLPLSLPSVRPDPSRVPLRSGASYLSFSPCGRYLLARSDTTPNAAHIFSFPPPSLPFFPQLHTVLLHERKVFTALWKPGQAGGYKLALGCEGKGAVYLWSDENEWEGDEDSDVRQGMADCCSVPARKFELKELAWSPDGNGLLLFDKDTFCCAFEVPADQQEQADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX23</accession>
    <name>M5FX23_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin beta-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_65685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629435.1">
        <property type="nucleotide sequence ID" value="XM_040775793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX23"/>
    <dbReference type="STRING" id="1858805.M5FX23"/>
    <dbReference type="GeneID" id="63690855"/>
    <dbReference type="HOGENOM" id="CLU_125172_2_0_1"/>
    <dbReference type="OMA" id="VQTEFAQ"/>
    <dbReference type="OrthoDB" id="248120at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000003">
        <property type="entry name" value="Prefoldin subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="73"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="129" mass="14795" checksum="FCAE26364B72CF07" modified="2013-05-29" version="1">MSTALESQLQKATKEYQRLETDLSNAIEARQRLDVQLTENEQVQKEFLSLTSDNEVFKLIGPVLVKQDQGEAKSNVEKRLEYIRNEISRLEVQLKDLNSKQERKRLELVNLQGQIESNQHSTSGAIPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXK8</accession>
    <name>M5FXK8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629650.1">
        <property type="nucleotide sequence ID" value="XM_040768341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXK8"/>
    <dbReference type="GeneID" id="63683403"/>
    <dbReference type="HOGENOM" id="CLU_2621978_0_0_1"/>
    <dbReference type="OrthoDB" id="3253416at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="8704" checksum="69E175BFC4DA43B4" modified="2013-05-29" version="1">MLDAKITGATKGKHKSMAYKSFSGDMEDKFHLTIHGWPLDTITNPSDIKNVPQLAKVHEALKDGKCFFHKMTAAELQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXU9</accession>
    <name>M5FXU9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_95008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628231.1">
        <property type="nucleotide sequence ID" value="XM_040777260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXU9"/>
    <dbReference type="STRING" id="1858805.M5FXU9"/>
    <dbReference type="GeneID" id="63692322"/>
    <dbReference type="HOGENOM" id="CLU_021993_3_1_1"/>
    <dbReference type="OMA" id="NPRIQST"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="74"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="481" mass="51684" checksum="B040CF332E1C4C9A" modified="2013-05-29" version="1">MSTTITTTVADAGYELQTFPSAARAQSDKSRSIRLVASEPAVPTPATATATATAVSEPPGSGDDSLTARQASLKLLSCCVCFLVAGLNDGSLGALLPYLIGTYNISPSLVGIMYGTSFAGWALAAGALPFTVALVGARGALLVGACLYALSQLVRIWTPPFPLFATTFFLASLAQAYQDAQANTFVASIKASHLWLGLIHAMYSLGLLVAPLVANTIAAQRAGQWALYYSVPFGIGLVNIALVLLAFFTKEDIRMRRRAGNTEAGQQPTNERYKQTWNEMKETVTHRSVWLISLFYFFYLGASFTIGGWIVLFLTDIRGLPLQTAGYIPTGYYLGTFLGRLFLPHPTHTWLGGEHYMLTIYCLLILCLQLLSWLVTSAISTSVAISLMGLLFGPWFAAGMQVSKQVMPRKIRPNALPLIFVIAQLGASVFPAVTGVIVASKGVGVLQPIALGLIVLTGGAWWFVPTAPREREREREAEAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYP2</accession>
    <name>M5FYP2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Urease accessory protein UreG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630050.1">
        <property type="nucleotide sequence ID" value="XM_040772401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYP2"/>
    <dbReference type="STRING" id="1858805.M5FYP2"/>
    <dbReference type="GeneID" id="63687463"/>
    <dbReference type="HOGENOM" id="CLU_072144_0_0_1"/>
    <dbReference type="OMA" id="KMRGDKP"/>
    <dbReference type="OrthoDB" id="10063137at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05540">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000208">
        <property type="entry name" value="Urease accessory protein UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715:SF0">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005624">
        <property type="entry name" value="Ni-bind_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="6">
        <location>
            <begin position="58"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28297" checksum="60F42483E6D03BA0" modified="2013-05-29" version="1">MHNHSRQFFALDDEYAQPGTWTPLEHGHTHEHLEHAGKFGDRVLPDYNHRDFKERGFTIGIGGPVGSGKTALTLALCQKLRDRFNIGVTTNDIFTREDQEFLIKNNALPAERIRAIETGGCPHAAIREDISANLHALEELQAEFGCQLLFVESGGDNLAANYSRELADYIIYVIDVSGGDKIPRKGGPGISQSDLLVINKTDLAPYVGASLEVMARDAAKIRDNGPTVFTSIKHGDGVDEIVDYVLSAWKASGASRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZA8</accession>
    <name>M5FZA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_21564</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630275.1">
        <property type="nucleotide sequence ID" value="XM_040772450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZA8"/>
    <dbReference type="STRING" id="1858805.M5FZA8"/>
    <dbReference type="GeneID" id="63687512"/>
    <dbReference type="HOGENOM" id="CLU_009281_2_2_1"/>
    <dbReference type="OMA" id="HKTDATN"/>
    <dbReference type="OrthoDB" id="5422795at2759"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07792">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000086">
        <property type="entry name" value="Glycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000108">
        <property type="entry name" value="Glycerol kinase, glycosomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="12">
        <location>
            <begin position="282"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="58291" checksum="EBC9A6BFA760DC23" modified="2013-05-29" version="1">MSQQEEFVGAIDCGTTSARFLVFNDVAEVIAEAQEEFPQYYPHPGWHEHEPDEIQEVVERCVEEAVENLEAKGHTAKSIKAIGITNQRETTVAWDRITGKALCKAIVWDDSRTRGVIHTLERRLKEKGIRVHDDHHINSVDDLVTITGTPLSTYFSAVKLTWMMEHHEEVKKAHEEDRLLFGTVDSWLVYNLTGGVKSGIHIIDVTNASRTLLFDIRKLQWSPALLEFFGFKENILPRIVSSSEVYAEMADGPLKGVPIAGIVGDQQAALVGNKCLEPGQAKNTYGTGAFLLWNTGEEVVKSDHGLITTVAYQPGPNAKPIYALEGSISTCGSSIKWLRDSMRLIEKASDMDKLARKVEDTGGVYFVPAFSGLLAPYWDSAAGGLLIGLSAYTTPEHIARATLEAIAYQTKAVLEAMAQDHGADLEHLKVDGGVTNSEMAMQIQADIGGFEVIRPLMRESTALGSALLAGSAVGLFGWDVRRPETLNRVNTQGNQTFNPKISTEERARMWVAWNRAVERSRGWEGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZD9</accession>
    <name>M5FZD9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Purine-cytosine permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_22455</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628127.1">
        <property type="nucleotide sequence ID" value="XM_040772808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZD9"/>
    <dbReference type="STRING" id="1858805.M5FZD9"/>
    <dbReference type="GeneID" id="63687870"/>
    <dbReference type="HOGENOM" id="CLU_026016_2_2_1"/>
    <dbReference type="OMA" id="LWLSANM"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="56800" checksum="C607EDFA36E9F655" modified="2013-05-29" version="1">MSSSPTSEIREKDLEKSQKDYYPQHVPDTIQEIRPTTGPLAALWAMVEKFDRYGVEVRGIERVKPEERNPTQSAWDACTMWMAANCNISTFSLGTLGTSIFYLSLRECFLCILFFNLLSTLPVAYFSTWGCKLGLRQMTIGRFSFGYYTSLVPVVLNLIACVGWSTINSIVGASVLRAVSPDSDHNIPVAAAIVIIAVLTTIVSLFGYKVVHAYERYSWYPVAVIFIILLGLSAKYMVSGPYGGTGSLEEGNILSFGAAIVGFGLGWSSLAADYTVSMPEKTPSWKIFCLTYAGLNIPLVLIETLGAAMTTVTPDEYQAAFADGGIGGLIGAGLSPAKGFGQFLLVLLALSIVGNNIPNMYSLALTAQVLGRWVQMIPRFFLVLVGTAVYIVLAIVGASHFEDWLDTLLVLLSYWLAIYSTILIEEHFIFRGGKWTNYMPNEYNNTRLLPLGLAALFALCCGIAGAVLGMATVWYVGVLGRLIGDPVFGGDIGFELALGFTAITYPPARWLEKRLTPSRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZH5</accession>
    <name>M5FZH5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628172.1">
        <property type="nucleotide sequence ID" value="XM_040771158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZH5"/>
    <dbReference type="GeneID" id="63686220"/>
    <dbReference type="HOGENOM" id="CLU_756549_0_0_1"/>
    <dbReference type="OrthoDB" id="3409573at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="366" mass="40137" checksum="3A37258DD397C9D1" modified="2013-05-29" version="1">MVVGNRSKEVVLGEVLELNRCAKDGAKGKGKMVEENSQGGSSKDHLPHRSNEDEADSVSLGSVYSQDDPNEASSTTHNNTCPNDMGTTLVYPHDPRFKHLMYYDLYLHILEGGDAATAMMVLDVIYVQDAMVHVSVHNKTILEMYCLVEPIPPFAPSLSPIPEDNNKVGTVIASPPLPQAPMAEELKSVLRNRMQHSDIACQAINEEYRHVGQAHPQESASSSSSLASVGSSSLASVGLTPFSRLPLGPNARAGYNGLADLFGRIVQMLGTVSTFFKKNEAVSKYKWWAWAGYQVAKGSGMLLLWIQLAIISCSTVMRYNLHTFIILLIMFIFCRAKGIAIHEVLFGILEDLAMKGRIVMGYCTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZI0</accession>
    <name>M5FZI0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_59937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623805.1">
        <property type="nucleotide sequence ID" value="XM_040775595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZI0"/>
    <dbReference type="STRING" id="1858805.M5FZI0"/>
    <dbReference type="GeneID" id="63690657"/>
    <dbReference type="HOGENOM" id="CLU_684377_0_0_1"/>
    <dbReference type="OMA" id="ATPECLL"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="224"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="377" mass="41816" checksum="80F2823C1EB378E9" modified="2013-05-29" version="1" fragment="single">FTVTLNNGIHAVTTPEAILERDTVIEQEFELIEHPKLEFTLTIRVRKDEHILAQLRPPPPPPVSLPSRESVVTTKSATPTQRSGFRALFGSPKKSKQTPKTSPPPPVPIPRAQSELPQPQVDYLAKHIGPDGTLAQASISFKDIARRSDTRIFETSYPLLARSSSSVPDTVTGSSVAVPSARTVGDIVLQVFRLPPLPGIEQDALPQSLEECQRGLRHVAWHKALYHEGILTQNGGDCSTWRRRRFRVIGAEMIASNDVTKKITATIDVGKAIALEDDQDPALKVTTGKTTITRSMNSDDDLYSYTGVQRSFRLIFEGGDEIGFFADTDEEKAKWMEVLKSRIGRVPTHPLWAEMLWQRQEELSKQAVAARASAQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZM8</accession>
    <name>M5FZM8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630375.1">
        <property type="nucleotide sequence ID" value="XM_040777566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZM8"/>
    <dbReference type="GeneID" id="63692628"/>
    <dbReference type="HOGENOM" id="CLU_1107085_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="27195" checksum="522070EA37CEBD7A" modified="2013-05-29" version="1">MYPDFSDDEPPQTEVNPAKRPRQPTTESNASTSRPHKRPSITEASPIMNADVALFAQQSEPEVVEVQAPGKAKAMPDKGKARAVSPARRAEVMPPPPVPKRGRKGRPRKDAAPVTPASKASKATLMSGVTKRVGGGRVVATFDHCVMRENLRLAIHTGDVIYARNLAKWAQMVGVSAVHTSFPPPFATRYFQDPTRASLDAAYHHVMQLAGIPIPMSLPPDSDTGEVDDMANPNTASEDEEDDDEPLLFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5G045</accession>
    <name>M5G045_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_22634</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628422.1">
        <property type="nucleotide sequence ID" value="XM_040772897.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G045"/>
    <dbReference type="GeneID" id="63687959"/>
    <dbReference type="HOGENOM" id="CLU_000192_0_2_1"/>
    <dbReference type="OMA" id="LEMHHQI"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 16" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 16" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="962"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1222"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1624"/>
            <end position="1642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1649"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1674"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="19">
        <location>
            <begin position="7"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="20">
        <location>
            <begin position="1880"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="601"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="16">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="843"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1781"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="849"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="109"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU01525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1938" mass="218740" checksum="00B57402A27D74EE" modified="2013-05-29" version="1">MSVPRPQDINDLALSPSTSDDVLVSVLRERFLSDTVYTAIGSSALVVVNPYKYVSSNADNVLLDYAAEYRDTDAHDDRHVKPPHIFQLANNAYFHMRRTNMDQCILLSGESGSGKSETRRLAIKSILELSVTSPGKKGGKMATQIPSGEYILESFGNARTLQNPNASRFGKYTELQFSERGRLCGIKTLDYYLEKSRVAGAPGGERNFHVFYYLCSGASQEERQHLKLADKSTFRYLGQRPTGGREAVTEDSQRFDRLKMAMKSVGLSKRHIAQTFQLLAAILHLGNIDFTMDKSRNEDAAVVKNVDQLEIVADFLGVQPHALEAVMQYKTKLVHKELCTIFLDPEGAGGNRDDLAKTLYSLLFALLNETMNQNLCRDDFLTFIGLFDLPGFQNISSSASRTNSLDQFCVNFANERLQNWVQKRIFERNNKEYEAEEIASLIPTIPFFDNSECIRLMSHQPGGLIHIMDDQARRQPKKNDHTMVEAFSKRWGNHSSFRAGQMDRSGFPTFTVNHYVGPVTYSAESWLERDTDALNPDFVSLLRGATLNADESPPLHMGGSEVTGSINPFVRSLFSAKAIATQAHPYNEDTIVAAQQPVMPMRAPSTRRKQSVRRARASQQVNSPPAVQEDEEPPREIKCVAGEFRTALDVLFETLDETQAWFVFCINPNDSQLPNQMEGRGVKAQVRSLGLPEVAKRLSVSFEASMTPIEFCDRYKSQMVMLGIGIEDDFRERITRTRDALDLGEQDVVVGKHKVFLSHTAFHVLENYLRASDIDEQKRNRNRELEREEVDRPTFDPFAPYSPLNAEVVDSPHPGVYHNPRSARTNSSAGLVMNAAPFRGAALDDGATDDGRSYRSGTDYDTRSRATSQKDEVMSMTSYAPTNNMFHNMDKQVIPEKDALPGEALEGETTEDLRESVGRRRWVFFCWMLTFWIPSFILSFVGRMKRMDIRQAWREKVAINMIIWFVCGCAIFVIAILGNLICPTQYVFSTSELQSHSFQNNPSQLYTAIRGEVFDLTNIAALHLTAVSVVPTKLITNYGGEDATSLFPVQVSALCNGVSGSVNPYVILDSTNTTTNIYAQYHDFRAFTNDYRPDWYFETMVMMRYKFRVGFMGYVPQEISDMANSGRAVAIYNGEVYEMTSYINIGPQVKVPNGFTPPTGIDTQFMSQQVQDLFTYNSGQDITKQLNSLNMDPTTLADQKTCLRNLFLIGKVDNRNSPQCLFANYILLALSVMMVSIIGFKFLAALQFGSARAPEDHDKFVICQIPCYTEGEDSLKKTIDSMAKLRYDDKRKLLFVICDGMIVGSGNDRPTPRIVLDILGADPNRDQEPLSFLSLGEGAKQHNMGKVYSGLYECEGHVVPYIVLVKVGKPTERSRPGNRGKRDSQMVLMHFLNKVHFNSPMNPLELEIYHQIKNVIGVNPTFYEYLFMVDADTTVDPMSLNRLISAMMHDKKVLGVCGETALSNARHSIVTMMQVYEYFISHHMAKAFESLFGSVTCLPGCFTLYRLRTPDSKKPLFISNQVIEEYSENRVDTLHMKNLLHLGEDRYLTTLLLKHFPNYKTQFVRDAHAWTVAPDEWKILLSQRRRWINSTVHNLAELVFLERLCGFCCFSMRFVVFIDLLSTLIQPVTVAYIVYLIVLVAGEHKPLPTISIILLAAVYGLQALVFIVRRKWDMVGWMFFYILAIPAFSFFLPLYSFWRMDDFSWGATRVVLGEKGKKMVVHDEGKFDPKAIPLKSWSDFENELWDKESNHSIGSWVPPKPGKEDYESRADSVYGRETYYDPDPYSRSRAPSQNMMHPPAFASGRNSPADVASLRPSMRGQYAANAYGSRPGSQVVYDPPEGYPPPNYPPSRQAFSRLPSTQSGLANVLNYDDQGANDGLPSDAEIEAAIRDILREADLNTVTKRGVRQQLERVFGIDLGPKKSFVNATIDRLLLNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0G6</accession>
    <name>M5G0G6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628522.1">
        <property type="nucleotide sequence ID" value="XM_040768600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0G6"/>
    <dbReference type="GeneID" id="63683662"/>
    <dbReference type="HOGENOM" id="CLU_877235_0_0_1"/>
    <dbReference type="OrthoDB" id="10673507at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="317" mass="32510" checksum="46D87E1A7CF7BFD3" modified="2013-05-29" version="1">MATPNAFGEPTLESLASQLIGSEGAWEAVEQGARAYEHSPAIVPGGFSQGGRPGTPGQDGGWAGWRGSAQGNGLAGVPGANAGGGTRLAGAPQRTVPAASHLRREESTDDEEEEWAFPEYPPYPAYPAYPPRHELPEHLRNLPYPAYPAYPAYPPYPGSGALPPPAVRSMGIPTHSHGRTSGTMHSLDHPPNAQAWSAEYGGSSSLAAAAAAGAYAHSALARGGGTARTGTPGSIWNPAVPPLSNVQSSMSGIGSTASPTPSNNPALMGLQSPPTVPGIPGRRMRERRPTHQRENSAGTGSAGSPTKSRRDRGGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0V5</accession>
    <name>M5G0V5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Arsenical-resistance protein ACR3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_94069</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630775.1">
        <property type="nucleotide sequence ID" value="XM_040777196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0V5"/>
    <dbReference type="STRING" id="1858805.M5G0V5"/>
    <dbReference type="GeneID" id="63692258"/>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OMA" id="MVLMWGY"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="400" mass="43348" checksum="A99F81428E5D3FE9" modified="2013-05-29" version="1">MRPSCRNCDFCDGLASMDPDTSLAAGTEEQEKGVDVKSLFKGLGFLDRYLALFVFLAMVLGVLLGVYREDDVHRAFGGAQWQGASIPILIGLLIMIWPILTKVSYESLPALFSTRRIWIHLGLSALLNWVVAPFVMLGLAWATMPEPALERERKGVILVGVARCIAMVLIWNGLACGDTQYCAILVGVNSVLQIVLFAPYALLFLNVLGGSSSPALILSYSSVATSVGIYLGIPLAAGILTRFIIKTMLSSKHQDLFFHYFSPLSLLGLLYTIIVLFAAQGQQIAANVGSVFRIFVPLILYFTIVWNCTFFGLYFLGRSRRGRALGGYDKAVVQAFTAGSSNFELAIAVAVASFGTESPEALAATIGPLVEVPVLLALSCVALLLRKKLDWTPKPNIVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G124</accession>
    <name>M5G124_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624380.1">
        <property type="nucleotide sequence ID" value="XM_040769254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G124"/>
    <dbReference type="GeneID" id="63684316"/>
    <dbReference type="HOGENOM" id="CLU_010693_2_0_1"/>
    <dbReference type="OMA" id="RCIARRI"/>
    <dbReference type="OrthoDB" id="2393824at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="761" mass="85423" checksum="3C1E9CDEFB3F2F1F" modified="2013-05-29" version="1">MGTLRWRSYLKNEIQPRLQQLIADKRQGIPFPVWSWHEKPHPKLEALWQNQSLPMFAKQPSVLLHGALQDNIVADDVVQALLKATRHSVIYGASRSGKTAVVLAALRKKWGVYIPCQVPGGGDIGSQDLEGTILQIKQDKSFTNDLSGVKTENADPAVLKKAVLTNTGIIRKRILPFLLARLSMMNLYLDLAVAADLTLDQQLLLWLCIQIFFLDCFAIDIFQILTDHIRIDDKHEEELRAMLATELQSIKAKVSHDSLLFCVDEAQAAVFGSEHCLRSTAEPDQTRPLLSGLLKALSDKLPGHRIIVSGTGLTMNTVEGAPRWATAKLQAYTMFNRLGAFEKREDIRQYITRFLPQTEDSEAVLNFFHTWLSGRYRFAAGAVETLLATGFQVPRIILQKFVFTITDYTVPILTQSPAAEELAKRLWSGTPLPRRLNVERLDQTKSPSNPRISLLSRFKQILFEWLLHTKVAGGANRTDVELVDRGFVRLRWRESDKPDIWDIIPGDPLVLLSVLAYLENNRESIEDSPGHDLTRTEAGGVGGHFECACVYHFATCFGKPRPLSDIFLAGLGDCKLNRKCELVSLNMKTSTYSIYSFDSKRISATSVNRYCNNFAETDEWLTNPDGIPICRPDEYFGGDIIFLLRDADGNAFWVIVQCKWTPRLLPLQELKDGASTVCPAQIYKSSPHRQNQTRAKMLGLQNIASDRKSDELRVLEVLAVLPGDAKIDRLKQFRQCCHGICLLGSSSELTQLVPFAVPSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G163</accession>
    <name>M5G163_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_79602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628812.1">
        <property type="nucleotide sequence ID" value="XM_040776403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G163"/>
    <dbReference type="STRING" id="1858805.M5G163"/>
    <dbReference type="GeneID" id="63691465"/>
    <dbReference type="HOGENOM" id="CLU_023620_5_1_1"/>
    <dbReference type="OMA" id="IPGPRCL"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="106"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="453" mass="50007" checksum="2C9540DA099727FA" modified="2013-05-29" version="1">MLGLTEYTDPTTRGSYRKHPIPVTNANTYADSPLLPVKHEIKGTDSNSVILFKDVKVLDSTGREPFPGDVLIRGERIVKVSAKINEDKVKETDPQVHIIEGKGRTLMSGLCDAHTHLSWNNSPDLEGLGHLPPEEHTIFAIRAARTYLDYGYTMCFGAASAKARLDCVIRDAINAGEIAGPRYLANAQEIARRHGALIDSISAFADGPEDITIAVLKNVALGADQVKLSMSGESITEKVMADENFFTDEETKAACDAAHKQGKRVCSHARSVDSVKMSARWGVDVIYHASFTDEETLDLLESKKDRIWVAPAINWITETLTSASEWGCTPEHAIEIGYKDELEEAIKSMKAMKARGIKLLPGGDYGFAWTPHGTYARDLEHFVNLFGYTPMEAIIAATAVLFMRPHELGKVLPGYYADLILVDGNPLDDIRILQDKDKLHYILIDGRVHKCMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G188</accession>
    <name>M5G188_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_14226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630895.1">
        <property type="nucleotide sequence ID" value="XM_040771024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G188"/>
    <dbReference type="STRING" id="1858805.M5G188"/>
    <dbReference type="GeneID" id="63686086"/>
    <dbReference type="HOGENOM" id="CLU_010595_1_1_1"/>
    <dbReference type="OMA" id="IALCRND"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="33565" checksum="228770ECA7FDF921" modified="2013-05-29" version="1">MATVEVLKPSTAYDPAQVNAHREYHKAQTPYFFPAGTDEAEWDRLNAQHYGIKAYFKGNRHGARWPKTPRRILELGVGTGAWATEVAAEFPKAQVVGVDVVQPRLGKTPQNFTFVSMNVLDDVWPFEPGSFDVVNCRFLLMHMPNFERVLNKAIDVTAPGGILMLADPASRFQAEGRPVPPEASKLYDVYWGYCKTQGIVPGTGPLFAPLLAASKKFSEVHELVLPACMGPWPKNERLHPFGEGMRKGIIDGARSLNSKVFEFGLTGEIVEGMVRQVLDPENRLYVDEYFVWARKKQEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1A2</accession>
    <name>M5G1A2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_48939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630910.1">
        <property type="nucleotide sequence ID" value="XM_040774874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1A2"/>
    <dbReference type="STRING" id="1858805.M5G1A2"/>
    <dbReference type="GeneID" id="63689936"/>
    <dbReference type="HOGENOM" id="CLU_001724_12_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 72B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045:SF31">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 76B1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="208" mass="23296" checksum="C257D1D75367BB2F" modified="2013-05-29" version="1" fragment="single">GPQSALYISWGSLLFPQKYIDVLIHALLEQDQLMPFVFAASSWDAVLPPSLKEEVDQSGRGIIVHWAPQQAVPAHPALGWMLTHCGSGGMSECLTRGVPLLAWPLFWDQPAHALWLSQVLDVAFEFLQVREGPVKGLAYRAGGLNVEGTREAVRREVREVLGMCRGEEGRRKRENALRVRGRVWEAVGQGGQVQRHLEELGRFLWRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1L3</accession>
    <name>M5G1L3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_65758</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629503.1">
        <property type="nucleotide sequence ID" value="XM_040775794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1L3"/>
    <dbReference type="STRING" id="1858805.M5G1L3"/>
    <dbReference type="GeneID" id="63690856"/>
    <dbReference type="HOGENOM" id="CLU_004962_0_0_1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="124"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="341" mass="38911" checksum="44AF838508CB9CD0" modified="2013-05-29" version="1">MNLNDVQKEVNIDSVIDRLLEVRGNRPGRIVNLHEYEIKHLCAKVREIFVAQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLFAYKIKYPENFFLIRGNHEAASTNRIYGFYDECKRRYNIKLWKIFTDCFNCLPIAAIIDDKIFCMHGGLSPDLQSMDQVRRVMRPTDLPDEGLLCDLLWADPDKDVTGWGANDRGVSYTFGPDIVTRFLDKHDLQLIVRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKPGRSSTSTMKKKGKATRFADSQSPYGDNFGSYGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X5</accession>
    <name>M5G1X5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_24749</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624655.1">
        <property type="nucleotide sequence ID" value="XM_040773835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1X5"/>
    <dbReference type="STRING" id="1858805.M5G1X5"/>
    <dbReference type="GeneID" id="63688897"/>
    <dbReference type="HOGENOM" id="CLU_022996_1_0_1"/>
    <dbReference type="OMA" id="EFLPYHW"/>
    <dbReference type="OrthoDB" id="10251154at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000378">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="265"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="10">
        <location>
            <begin position="355"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="466"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="559" mass="62414" checksum="FBD9BDEEF864FB1D" modified="2013-05-29" version="1">MTVTAIAEHTHLPKSLALVEDELPKVHPADTKVASRFLQSRLSKQHIQKQHALLARKDAELLLPDVPGGLEAEGELERTWKVGQEDIVKEIGLETSRSQRDIKLDGGPYTLRWTRNGRHLAIAGTSGHVATFDWQKGNVLAELQLRESVRDITFLHDYTMFAVAQKKYVYIYDASGVELHRLSTHVDVNRLEFLPYHFLLVSVGNSGYLKYQDTSTGQMVTELRTKMGACATMCQNLHNAVINLGHQHGSVTLWVPNMPKPAVQLQAHLGPVTGLAVDAKTEGRYLASAGLDSKVKIWDSRNWGKCVKEWQPLESGSGGIVEWSGRGLLAFSRGRRVNVYAPNTLLDGSAKPPALYMSHHLPVQTCSIRFRQFEDVLAVGHAAGFSTIIIPGSGEPNPDSFEADIYETRTGRREREVRSLLDKLQPDMISLDANFIGSVASAPKRPYAAAPVPFSRLARTERLQIQGKSDEPMEQDEEDEEEDTQDTSKPEKERLKMRGKGKSMKRFLRKKRKNVIDPATVAIKAKMAAIKEQQEKRKQAAEGSLQPERKGALSRFHKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G256</accession>
    <name>M5G256_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_26161</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629668.1">
        <property type="nucleotide sequence ID" value="XM_040774278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G256"/>
    <dbReference type="STRING" id="1858805.M5G256"/>
    <dbReference type="GeneID" id="63689340"/>
    <dbReference type="HOGENOM" id="CLU_001265_52_2_1"/>
    <dbReference type="OMA" id="CALYACI"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="527" mass="57541" checksum="1B4C83DEA03B89CF" modified="2013-05-29" version="1" fragment="single">PAEEKPAAVEDALEAHEDVLARAKGEGISTAYELKCLVVNDVLQRQIGMGRYQWYLFVLSGWGWMADNIWLQGIAIILPEVQRELVPAGSTNLHVEFATLSLYVGLILGATTWGILSDVIGRRLSWNITLFIAGVFGIAAGASPTLVALCFLSGCIGFGVGGNLPVDGMLFLEFIPKSHQPLLTLLSAWWSLGQLLASLVAWPFIIRFSCDPTAVTCTREENPGWRYTFYTLGALTFVMFVFRYFVFDMQESPKYLIAKGRDEEAIAVLQHVARVNRVTLDLTVEDLQRAVRAELGDEPQLPAKSAWESVKEGMTTFDLGHVRPLFSTPRLAVNTSLVIFIWGCLGLAYPLYNGFVTLYLTNAGAAFGDTSLNTTYRNYAIFSILGIPGSLIACVLVEWKGKWAFGGRKFAMALSTVLSGLFLFLFTTAKTEPAILGWNCATSLTENAMYGVLYAYTPEVFPGPHRGTGDGLASCFNRICGLMAPIIKIYAGATNASAPIFVSASLFVVASIFMLLLPIETYGKAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2E3</accession>
    <name>M5G2E3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 4E</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF-4F 25 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">mRNA cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_24854</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624835.1">
        <property type="nucleotide sequence ID" value="XM_040773883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2E3"/>
    <dbReference type="STRING" id="1858805.M5G2E3"/>
    <dbReference type="GeneID" id="63688945"/>
    <dbReference type="HOGENOM" id="CLU_043552_2_0_1"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000011">
        <property type="entry name" value="Eukaryotic translation initiation factor 4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="392" mass="42902" checksum="254CE34833A0DD2C" modified="2013-05-29" version="1">MSTTTTASTLPAPAAQASRAALEAALADKTNIPPPSGAALNGISSQPAKKRDELDELPDFEGEDDFPEITPQPELVKPTNGTDSTHATVGGLDEDGEENDELEDGEEEDGEIEEHTQEDYETRDVAQIMEEQEDRIRTVFDDPNGFNVKHPLFSSWTLWFDSPATKGRNLPPTPLTSAAQSFPPTPGGVPPTPGGGSWMDDIKKVITFDSVEEFWGLYNNIVPPSTLSQKANYYLFREGIIPAWEDAANKDGGKWSIQLPKDKTRPHIDKMWLYTMLAAIGETFDPPHAESTLPPQSLITGVIVSTRPQFYRISIWTRSAPASSSTSITNYDPAAEAALTQRIMAIGAHFKTSVLGYDIKAKLTGGLSTEVEFQSHKESEKKQRGQSKKLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G7</accession>
    <name>M5G2G7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Meiotic sister-chromatid recombination aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629778.1">
        <property type="nucleotide sequence ID" value="XM_040772563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G7"/>
    <dbReference type="STRING" id="1858805.M5G2G7"/>
    <dbReference type="GeneID" id="63687625"/>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OMA" id="ILMRGTF"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07098">
        <property type="entry name" value="ALDH_F15-22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="80"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="67378" checksum="616F75442AEFB3B2" modified="2013-05-29" version="1">MSMSASPSMLLTALLGFIISGILIVVRRHDWNRKKSVKFEWAAPEQSFLNYEGTTILNPTLKSHLEDPALLPAEHEPGVEYITCFDPSTSLHISTLPSLNQLQIAERISLARESQRTWSQSTFDQRRRVMRSLLAWVLENSEGIARVACRDTGKTMIDAAFGEILTTCAKLEWVIKYGEKELRPSRRRVPLLLMHKKAHVYYEPKGVVAAVVSWNYPIHNALGPIIAALFAGNAILLKASEQVAWSSTWVIGAVRQCLQACGHDPDVVQLVLAYPETVETLTRSPVVRHITFIGSEEVGRKVLIAAADNLTPVTLELGGKDAAILLPSADLKAFSSHWMRGVFQSMGQNCIGIERFIVHSSIYDQFLSLMLDRVRKLRMGSVLNSTPEGWVSTIDVGSLISHAHAERIARIVARAREEGAEVLTGGNVVSHPYAPGGAWFEPTVIANVTEEMDIARLEVFGPVMVVMRYEGGWEEAVRLANGCTYGLGASVFGNDRRECERVVRALRCGMVAVNDFGVFYLNQDLPFGGVKSSGFGRFSGPEGLQSLCDPKSVIQDRYFSWIRTPIPRAVDYPIRSLVSSWEFVAGLGEAVWGEGWAERVGGVWRLVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2K0</accession>
    <name>M5G2K0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_58306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624890.1">
        <property type="nucleotide sequence ID" value="XM_040775492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2K0"/>
    <dbReference type="STRING" id="1858805.M5G2K0"/>
    <dbReference type="GeneID" id="63690554"/>
    <dbReference type="HOGENOM" id="CLU_013253_1_0_1"/>
    <dbReference type="OMA" id="FMQYMRA"/>
    <dbReference type="OrthoDB" id="15189at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="290" mass="30791" checksum="59CB516AC6BE0A1D" modified="2013-05-29" version="1" fragment="single">FDTGSSDFFLPDPSCFDCGSHHTYDPSQSSTSTYLGNDFFLSYGDGSESFGMQYNDAVSVSGLTVQVQTLGAAVSYSVGFERMVPDGLMGLAWPQLSDFPATPFIFNLYDQGTLSSNSFSFKLAESGSSLFIGGADSSLYTGSFSYTPVTEQGFWQVTADALLIGDTVIANDQDSVVDSGTTLVIVDPITAGLLYSNIPGAQKDSSVGRGIYTMPCDNVPSNVKIIFAGQTVTIPPDVFNFGPLSQGSTTCIGGVAAGKFGFWILGDVFMRNVYTQFDMENYQVGIAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2L7</accession>
    <name>M5G2L7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_111521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT98007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624905.1">
        <property type="nucleotide sequence ID" value="XM_040769252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2L7"/>
    <dbReference type="STRING" id="1858805.M5G2L7"/>
    <dbReference type="GeneID" id="63684314"/>
    <dbReference type="HOGENOM" id="CLU_008455_13_8_1"/>
    <dbReference type="OMA" id="EMRLWTC"/>
    <dbReference type="OrthoDB" id="2533084at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="521"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="562" mass="62697" checksum="59C7163AC6C5BB17" modified="2013-05-29" version="1">MSTADLEKTPHAIEAVGTEGTNNGNASPAYHAVGEKGSDQQVENVLEHELTAHLELLDAAHQNGRLVVEIEEARREYGAHVAVKFKLTPDGKYILWPQPTEDPRDPLNWSWNKKMLTLVVLTMASIVPDFNSSIGIACLFPLAEQFNTTVNHVNNLTSNWSIFLLGPGGVVAVILVNVIGRLPILFWSQILGVAFLIGCTVAPDLATVAGMRCLSAFFSTAPQVTGLFIVRDIFFFHQEARMLNAWAFGFVVSPYLGPFLFGFLVQRQTWRWAYGIGCIYEGIVVLLIVLFVEETLYERDSKDRPKIETGMWARIKALVGITGYQRRHFHMPFWTSFWRPFLVNFQPQEILSLAYVALNFAWAIGINTTLVVFLQSPPPLGYSFSGDAVAVFYLTPIIATVLGEIVSHYLQDFFTNRYIRRHNGVFEPEARLWMCYIGSTLNFAGLMCLGGTLQNHASIAGLVFGWGLFTLGMMIIISAMYTYMSDAFPAYQGEVSCLFNLWRTFAGFAVAYFQVPWSEKSGALVVFGCEAAIVVFIFVAVVPILQIWGKAIRTRFSSLSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2M3</accession>
    <name>M5G2M3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629359.1">
        <property type="nucleotide sequence ID" value="XM_040772674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2M3"/>
    <dbReference type="GeneID" id="63687736"/>
    <dbReference type="HOGENOM" id="CLU_141735_0_0_1"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="157" mass="16160" checksum="026577CED984A141" modified="2013-05-29" version="1">MSIKGAAFELDGNPSALASTALLYSLLLPALLPSSTMQSFVFVLALVASSMAYVLPRQSATLTCGTANLQCCNTLALASEPLIANALGLENLQIPGPDITVGLNCTTPPNDGTPVTAQCIGILSCCTSINIGVNSDISEDCTMTGIGTKRDVAYEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2T3</accession>
    <name>M5G2T3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="12">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 12">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_118845</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624970.1">
        <property type="nucleotide sequence ID" value="XM_040770667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2T3"/>
    <dbReference type="STRING" id="1858805.M5G2T3"/>
    <dbReference type="GeneID" id="63685729"/>
    <dbReference type="HOGENOM" id="CLU_076902_2_1_1"/>
    <dbReference type="OMA" id="DVKEMWT"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000018">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="30"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT98072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12880" checksum="5D4E98E583C64CA7" modified="2013-05-29" version="1">MSQYAQTPKSELDEAQLRELEEYEISQGPLSVLQQSVRNHTQILISLRNNRKLLARVKAFDRHTNMVLENVKEMWTEVPKGKGKKPVNKDRFISKMFLRGDSVILVLRNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Y3</accession>
    <name>M5G2Y3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625020.1">
        <property type="nucleotide sequence ID" value="XM_040771342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Y3"/>
    <dbReference type="GeneID" id="63686404"/>
    <dbReference type="HOGENOM" id="CLU_1283219_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="215" mass="24794" checksum="EB6A7080810A713A" modified="2013-05-29" version="1">MSLHSQPAPLQPIRTPHYQLNNHGITYNPSWIALSPYPLLDLYGFLETSLANNDTPAPSLTANGEPASNPSTKSEHTRKFENWHLSLITSRKFETEYWTLKQWLEARIKVMPYFLDKQATESFSYSEEDEAKMAYMNLHQPVREALNSVLRCAGSTWRVEWKAEVTTDGGRSDQLLVALRKDVRYQSNYDWKECSRHRANPAPTQYALCIVEDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3B0</accession>
    <name>M5G3B0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA polymerase II-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_115414</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the RPAP3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630073.1">
        <property type="nucleotide sequence ID" value="XM_040770000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3B0"/>
    <dbReference type="STRING" id="1858805.M5G3B0"/>
    <dbReference type="GeneID" id="63685062"/>
    <dbReference type="HOGENOM" id="CLU_023272_0_0_1"/>
    <dbReference type="OMA" id="NGTHELF"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025986">
        <property type="entry name" value="RPAP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13877">
        <property type="entry name" value="RPAP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="RNA-polymerase II-associated protein 3-like C-terminal" evidence="6">
        <location>
            <begin position="283"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="41529" checksum="AE16836831350CE5" modified="2013-05-29" version="1">MSTPSEAKENGNKAFKAGQYDIAVGHYTRAVVLSQSSDVPVDPVFYLNRAAAYLKLEKYEDAARDCTLALGLKREVKALFRRAQARLGAGDERGAREDLDEALLLEPMNQAVKLLLSSLTQPTKEKTSATPSNAGEHAAPSTSSPRRRRIPITLVDTPSSAAKPLKSALKSSSAPVATPAASTDLLTAVSTTRLTHTPVRSSALVGETSSATSAPAPSFAAAKATRERRVGGGMFKADGTGRIIGSPGPGQPQLSTSSPKSVKEVVERPPVLAEEKVVLPSVPKRASEFVLNLRELGEHARWAYLQLIPPANLPVFFGSALEPDTLSSLIHVLSSVTPPRPLVAEYLRAIPRCARFGTMRLFLGAGEEEMVRGMVGELGDEGLRKEWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3N5</accession>
    <name>M5G3N5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_50827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629724.1">
        <property type="nucleotide sequence ID" value="XM_040775011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3N5"/>
    <dbReference type="STRING" id="1858805.M5G3N5"/>
    <dbReference type="GeneID" id="63690073"/>
    <dbReference type="HOGENOM" id="CLU_101498_0_0_1"/>
    <dbReference type="OMA" id="RWISAHI"/>
    <dbReference type="OrthoDB" id="5551751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040200">
        <property type="entry name" value="Mug57-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156:SF1">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="16"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="166" mass="18559" checksum="4922B04C7B82C619" modified="2013-05-29" version="1">MGDQVDTDAPDPTFNPPTLADILTVRSAGSIWYDYAREVESVSLRLSDTSAMSKSTLLVPVNKAVLALHRKPHEGPAPDGDDMEITDEKTRVNVERWVSVHIIPVCHLLSRNAYPTLLDGRHVYFKQISESGWKWEQYAVNGTIRILDQVHASNGDIYFINGVLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G435</accession>
    <name>M5G435_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_76068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631920.1">
        <property type="nucleotide sequence ID" value="XM_040776178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G435"/>
    <dbReference type="STRING" id="1858805.M5G435"/>
    <dbReference type="GeneID" id="63691240"/>
    <dbReference type="HOGENOM" id="CLU_023867_0_1_1"/>
    <dbReference type="OMA" id="CFVPRGV"/>
    <dbReference type="OrthoDB" id="270624at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="287"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="426"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="527"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="553" mass="61122" checksum="01D529862E83E5E8" modified="2013-05-29" version="1">MASLISATAWVARGVAQRHPTKYKLDEAELERVSKLARIDIEDARRELAKASKQVEQWDAEKTDGDLSDEDEAWEDEPLEVNVAADEADDTKMDVDEVPTDANDMSIYHLEDYDQESKSVAAGPFSNIKGLSYYPDNEDDPYITLKEDPEEDERQELEVLPTDNVLVVAKTEDEISQLEIYIYEETTESLYVHHDIMLPSFPLCLEWLEFPVASSSTSSSDTTVNRGNYIAVGTMDPEIEIWNLDTLDSLYPDALLGRPDKTAAHVPTPVGTGKKKKKKMKARTTSSDHHVDAVLSLSWNKTHRQLLASASADRTVKLWDLSRPSTDPAIRSLEVHKDKVQAVEWNQLEPTVILTGSYDRTVRIFDSRAPTAGVGAIVGADVEALRWDPWDANRFYVSLENGIVLNFDARTLPTDLSSPSPAQFTLSAHDGAVSALDVNPHIRGCLATGGTDKMIKVWNINEPEEGKREISLVTSRELGVGKVFSVTWSPDDPLTLAAAGSKAKLQLWEVGLNPGVRKTFSQKLKDAGREVKDKEGGGVIGVDSEGEESGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4U1</accession>
    <name>M5G4U1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627774.1">
        <property type="nucleotide sequence ID" value="XM_040771184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4U1"/>
    <dbReference type="GeneID" id="63686246"/>
    <dbReference type="HOGENOM" id="CLU_2133430_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067589" evidence="1">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="11771" checksum="2BC025744DE99427" modified="2013-05-29" version="1">MATASLGVFLLLAFWVFAAGHGGVCSSIVAAACYIWGAIKIIWAWTSLQAIAQFIKDLAILLDALKPALNALMIVLEEMCAVEERGRALGVGGAGVGVGGGVGARVGGMGLGGVGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V0</accession>
    <name>M5G4V0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Carnitine O-acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="16">2.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_78158</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA</text>
            <dbReference type="Rhea" id="RHEA:21136"/>
            <dbReference type="ChEBI" id="CHEBI:16347"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57589"/>
            <dbReference type="EC" id="2.3.1.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="16"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630144.1">
        <property type="nucleotide sequence ID" value="XM_040776317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V0"/>
    <dbReference type="STRING" id="1858805.M5G4V0"/>
    <dbReference type="GeneID" id="63691379"/>
    <dbReference type="HOGENOM" id="CLU_013513_5_1_1"/>
    <dbReference type="OMA" id="KMDGTPT"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000007">
        <property type="entry name" value="Carnitine O-acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 21" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="20">
        <location>
            <begin position="19"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="607"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU03250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="634" mass="71594" checksum="BC4D3523E7C8CB87" modified="2013-05-29" version="1">MSDPSLPPMHRYQPFIPSLPLPSLAHTIPLYLSSIKPHCTPSEYALAKSEADDFLLSPLAALLQSRLEQRRQDEEQKAASSDVQGAIQGIGGNWLADWWNALAYNQFRDPVVPWVSYYYVHKDAETREKPERRAAQLVRGAMLFRKLVESGTLEPDKMRQTPLDMSSFRYLFNSARYPHPEEDYTKKFDPGEHGHAVFVRKNRLFKLQAEGLRLDQLETAIRKIYALATESAPAPSVGSLTSAPRTFWASARALLTQNKGNDRVLEEIDSAVVVVALDEERPVTREEIGWGCWAGKKGGGGRGRWFDKHQFIVFDNARSGFLGEHSAMDGTPTLRMNEFILAALEAGKLESPKKDQDEGKSNPLNLDPEELVFEVNDQVKEKIAESETMFDEVMAKHEMRVLHYTAYGSDLIKSYKCSPDAWAQLVMQLAWHLSFSRPGVCYESCQTRKFRRGRTEVIRSSSEESRLWAEGMLDPDVSDGVRKEMFLKAVQRHLEYAGQAANGLGVDRHLLGLRMVLRPSESHPFLDSPLMQKTKNWEMSTSQLSSAYVQGWGYAEVVPEGYGLAYAIHPDHLRWTITCLKGEGEGGRAERMAWYIEEAAGRVRRMMRSAREEEKGLEREGEEPAGPAGGRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G514</accession>
    <name>M5G514_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632250.1">
        <property type="nucleotide sequence ID" value="XM_040771703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G514"/>
    <dbReference type="GeneID" id="63686765"/>
    <dbReference type="HOGENOM" id="CLU_1539993_0_0_1"/>
    <dbReference type="OrthoDB" id="3200438at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="174" mass="18516" checksum="A9D22F1FFF128165" modified="2013-05-29" version="1">MAQCTLSSSSFSACGLGSPLASTLSSTPSPVPSTLGGTETEGCWSAMQDEPVVNQVQPDFLEAAEAMRIDDSPGDVDADADMDQKNLIPSMSSMLSKSFIIPAVLLQPPTPLLHQSPRHSHVPILPPPLPKSSAHAVSSRTTGLTVSRRRFIMGPREGCEKCRLRVPGHYGHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G543</accession>
    <name>M5G543_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Membrane magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_105940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane magnesium transporter (TC 1.A.67) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630678.1">
        <property type="nucleotide sequence ID" value="XM_040768172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G543"/>
    <dbReference type="STRING" id="1858805.M5G543"/>
    <dbReference type="GeneID" id="63683234"/>
    <dbReference type="HOGENOM" id="CLU_122437_2_0_1"/>
    <dbReference type="OMA" id="CYGIVHL"/>
    <dbReference type="OrthoDB" id="44756at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018937">
        <property type="entry name" value="MMgT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10270">
        <property type="entry name" value="MMgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11736" checksum="2698C2F12529D582" modified="2013-05-29" version="1">MSSSNAAIGQILLAVSIFGLLHSAFSSYEQLSKMKAASDPVQLPAIDVMAEAVISLVVFTFGAAFWSPELKPNTWAAEMAHRTIDQMNSRPGFARIGHRGRFLPGKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Y2</accession>
    <name>M5G5Y2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628094.1">
        <property type="nucleotide sequence ID" value="XM_040773027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Y2"/>
    <dbReference type="GeneID" id="63688089"/>
    <dbReference type="HOGENOM" id="CLU_1722307_0_0_1"/>
    <dbReference type="OrthoDB" id="10474783at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="16332" checksum="15867DD82C752E84" modified="2013-05-29" version="1">MATDSKILTPNPGASFHTGSVIAFTYNLVYDSGLYFTPTVDILLQKKGNDFAVEIANAITPDKSNFENGVLSYPINLASFVNADFVAGEYRLITIQHNTQSIAVHDGHLQTRQVTGDQELRLTYNLGPGPVQPGGPISLEPGPVIIQQDGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G619</accession>
    <name>M5G619_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_109912</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626085.1">
        <property type="nucleotide sequence ID" value="XM_040768968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G619"/>
    <dbReference type="STRING" id="1858805.M5G619"/>
    <dbReference type="GeneID" id="63684030"/>
    <dbReference type="HOGENOM" id="CLU_019415_0_0_1"/>
    <dbReference type="OMA" id="ACELVLC"/>
    <dbReference type="OrthoDB" id="4703at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052416">
        <property type="entry name" value="GTF3C_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052">
        <property type="entry name" value="RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="681"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="810" mass="89398" checksum="E50387BC078531EF" modified="2013-05-29" version="1">MELRKKTPVSYASLFEGPLSDLEETGSGQESESTRKNKGKSRTIPAESEEESDEYQPVDELPEDPSPPPSDADAEEEKEVEVENEEPTTKDDRFEDDSTPRKAFVGGGANSKAFRKMLRRTPSPPPDAPKRVQLERLAPFVNKVTSSTHQAKFSTRFRAVSLYFPLTTRRLASEPEAYGFGGWGTEVPTRCSGETGPLKRLMTAETKMNSGPRWETLEDRGWFRESTETDARPRVWEEVRIQRKCLKILSQEEAAPYLPSSSVLSENGASLPPPPLSCYFGRFGEQQKRTMNMLDSFPMSEYIPSSNAHILNAGGPVHGLSWCPVHPFDFPDNTPLTHWLAVSTFASALDQPTIGQRCEIGAEKGCIQIWSVEKEGAKCEIVLCLEDGPAWQIEWCPLPANDVKGSLRKMGLLAGCFRSGHVCIYAVPYPETIRQLQGKAKGKGKVVAVEGEPVHVQLQPIVRLSVDDAGCVCFDWANSGLIASGSVAVFDIASIFQNLDNPDPVLRLPTHYLPMHQTCVCSVAWVRAPPQGIDGRLQLQGNPTLLASTAYDGQKVLVDIRDGVTSVLERMRDWGTAVKFSTFSGGPIFVEQDYRIKHISLATVNLGRGTMLMDATGPIWDLTTSDFHHGIAVASADGAVHYGTSGRQHSKTAPRIVQPLYQIDYSRNSGELRMLEQLQPREPRQTEETYAMNKKKRESRKTKVPSEGVTDGVEIPPTSDGAEDRITQATGAWSPEVSIYRVSWCNGAGMARAQMLASGGASGLVRIDWVRGTWEKGIMPWRKVEILRGEVDGVDDDVEKQAAEDAEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6G3</accession>
    <name>M5G6G3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632740.1">
        <property type="nucleotide sequence ID" value="XM_040767907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6G3"/>
    <dbReference type="STRING" id="1858805.M5G6G3"/>
    <dbReference type="GeneID" id="63682969"/>
    <dbReference type="HOGENOM" id="CLU_006580_0_1_1"/>
    <dbReference type="OrthoDB" id="1534087at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="189"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1050" mass="116751" checksum="B0036B614B0DC056" modified="2013-05-29" version="1">MALSNDSNASTEEEETLPSKLAALKRAVNPILGKMADLALEALDIREELTENQAGLDALALRVAEVTEDILVKASAMQEGQLMQSQKFKRLQLCVDEISSFLREQAIPDIGRRMARIGELERIKAEVDTKNHRLTETLTAFIADISMDVLRAVTVTAAVGNPTIPQVARSTSLPITRLPPKLRIFRGREDVVKQIVSCLLRPDPGHIAILGMGGMGKTDTAATVLHHEDIKRKYGSNRVFVSCDGITTADGIISTLATALKSPSTQESDPTALLTHHLESVEGFVLLVLDNLESAWDTPDRTAVEELLTHLSNVLNLSLVITMRGTQGPMGVDWSQPLLPPLDALDSSTARQIYLANGGRSDDHLDELLQELDGWPLAVVLMAYQGQTQWPSQLLSAYRREQTALMSIRPGDRRTSVEVSISLSLQCQAVSDAFEALELLGLLCLLPDGMEEDILQTALPDMHNIPQSIRVLQHVSLVTRLEGGELKVLSPIRTYVLRVCAPSMRHRLTLEDFFIQHMQHILVLCGVEESSPDQSEDLVKVITKNFGNMLSVFSRAIDDPHIRQEILDAVHALCSAAIMIGYGDCPVLVKKAAGASSPFPEFKHTTGQLYLVLALYYSTSSRFDDAFKTIEQARNVDEAVHHIQQLLNGRLQEEEAEENIINALTEARDLFVARNLQYEAVFPPLCTQQLCLLALDAGRFEEAIELGMASKEAFEALSFPQGIYMFMQLLGWTLAAFAGFMKIENREVAATCQRILSEIHCRTGRFLEALDDCSLAEEAARIMDNEDSLWATRREQARLNALLGNLVEAEEQLSGAIRFFLQLGDKLKGAGCRLNLSFVLEARGMHDKAVDEIRSALRLCEDLKVDQAIALCKGFLGKAIAKPRPLTAASVAEAEQLFREALQVFDANDNLHHATSNLLNRTLDVNNTLGPQAFLRKDLVYLWREQDRHDGETLQRIQEALELFKKKDNRSEMAACYGIIASILADQGLRDEATSNVERAQCIYEELRFPPGQARCRMLLKQLADWGEPESVPERPEKRHSFIRKWLAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6W6</accession>
    <name>M5G6W6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="6 12">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_44893</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="6 12"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632890.1">
        <property type="nucleotide sequence ID" value="XM_040774612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6W6"/>
    <dbReference type="STRING" id="1858805.M5G6W6"/>
    <dbReference type="GeneID" id="63689674"/>
    <dbReference type="HOGENOM" id="CLU_040933_0_0_1"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000001">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="14">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="42089" checksum="93F73C0EB87564A2" modified="2013-05-29" version="1">MVEATAQSLTGNDFPPLKNDLILRAARGERTERAPVWVMRQAGRYLPEFRKVREKHAFFDICQTPALATEITLQPIRRYAGLLDAAIIFSDILVIPQAMGMIVEMPEGKGPTFPHPLADPEDLSRLKHPVNVDQELGYVFDAITMTRKELKGEVPLIGFCGSPWTLMAYMIQGGGSRGGFHSAKRWIFQYPTASKELLSRITTICVDFLIGQVRAGAQLVQVFDSWASELSPHDFQEFSLPYLCIIAHRVKSGLSEVGMEPVPMILFAKGANYALEELAITGGYDVLGLDWCIDPLVARHLVGDSVALQGNIDPDILYGGKEAIQREVKRMCASFRSNTTDGPKGWIANLGHGITPGVSTEDMGHFLSCVHKYSRQGDEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G756</accession>
    <name>M5G756_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_116732</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628544.1">
        <property type="nucleotide sequence ID" value="XM_040770254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G756"/>
    <dbReference type="STRING" id="1858805.M5G756"/>
    <dbReference type="GeneID" id="63685316"/>
    <dbReference type="HOGENOM" id="CLU_1120153_0_0_1"/>
    <dbReference type="OrthoDB" id="2359117at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="110"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="25459" checksum="13444D00D5F486E0" modified="2013-05-29" version="1">MYLARTLQTRLQYARLKVEHGWTKQTLNEVENLYFHHTRSKLPTTTSLQAAAAVKQEKEQSKLSLPLQSPMDTQPSATEPLDLTALHLPAEIWHSLQGAISSGAFGPLSQARTPTLPTRAFPGGSILSPPSGQPSEPSTPVRTSHHSHSRPPGSSSPTKHSHGSSSASSYPSVLSTSPAHSRSALAGAGVGAQVLTYDTFWSSLSAGSNSLAGLGAGAGGSVAGRTGAGKELQGLGIAALSPGAGGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Q5</accession>
    <name>M5G7Q5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_93207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631673.1">
        <property type="nucleotide sequence ID" value="XM_040777135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Q5"/>
    <dbReference type="STRING" id="1858805.M5G7Q5"/>
    <dbReference type="ESTHER" id="dacsp-m5g7q5">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63692197"/>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OMA" id="YICPGID"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140984" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="36"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="542" mass="59193" checksum="7BD63B6AAAE27C1C" modified="2013-05-29" version="1">MLFRVALSLAALAGLPLVDAVDPLVKLNYITYRGVARSTGVTEWLGIRYAAPPLGELRWRAPQAPLNNETVIEADTHGLICLSTPGTPGDPTTSEDCLYLDVYAPSNASSSSKLPVYLFIQGGGFNVDSNPNYNGTGLIQASEMNIVIVNFNYRVGLYGFLASQEVVDNGNTNVGLLDQRMVMQWVQQYISQFGGDPEHVVLGGDSAGGASILLHLTAYGGRDDGLFQAAAAESATFGNMLTISQSQYQYDAIIERVGCGYEVVEDTLGCLRSLNVSYLQANNYNVPYPNLGAGASAPIYMYQPTIDGGLITDYSYRLLQQGHFIKVPVIFGDDTNGGTIFTPKNTSSYQEMDQFLNDQFSAMTANQLLIMNAMYPPAETYPDSGPFWRTVSNAYGEMRFMCPSQAVGSAYNQFSAAGAWIYSYNVMDPLEMEGGYGVPHTIEINAIWGPYNVAPGSAPASYYPGQSNAAIIPIIQGYWTSFIRTYNPNIYRLAGSPEWVQWNAWAKDRLLFQTNATAMEIVDYGQQARCAYLQSIGVLTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T2</accession>
    <name>M5G8T2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_15595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629159.1">
        <property type="nucleotide sequence ID" value="XM_040771122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T2"/>
    <dbReference type="GeneID" id="63686184"/>
    <dbReference type="HOGENOM" id="CLU_1547527_0_0_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="19140" checksum="299118A391C1F9F5" modified="2013-05-29" version="1">MPLTQYPGGPVDKPVYATAERLGVAPEQVLLPWIKSKGAVILTTISKKEQLERYQAVANIDLTDEDIAHWSKFVGPTGVASLKVHPDKNPSPEAATLFHALTQAYNFLPDPTQRSALDASLAARRARAAQLAASSEKKCTMLEELECAERAAKRFKVDSLAEERKKREEEERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y3</accession>
    <name>M5G8Y3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_23199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627125.1">
        <property type="nucleotide sequence ID" value="XM_040773150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Y3"/>
    <dbReference type="STRING" id="1858805.M5G8Y3"/>
    <dbReference type="GeneID" id="63688212"/>
    <dbReference type="HOGENOM" id="CLU_047181_1_0_1"/>
    <dbReference type="OMA" id="HINTPSI"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000009">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="12">
        <location>
            <begin position="2"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="13">
        <location>
            <begin position="148"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="8"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="154"/>
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        <ligand>
            <name>substrate</name>
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    <feature type="binding site" evidence="10">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
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        </source>
    </evidence>
    <sequence length="336" mass="34914" checksum="B0FAF22EF4356427" modified="2013-05-29" version="1">MVKVVVLGAAGGIGQPLSLLLKTNPVVTGLSLYDIVNAPGVAVDLSHINTPAKVEGFLPPNEGLKQALTGAEIVVIPAGVPRKPGMTRDDLFKINAGIVRDLATGIATTAPKAFVLVISNPVNSTVPIVVEVFKKHGVFDPKRIFGVTTLDVVRASTFAAEALQEPSLASKLVVPVIGGHSGVTILPIFSQAQPPLPASFLENKETLEAITHRVRYGGDEVVKAKDGAGSATLSMAYAGATFVEKVVRAVSGEKNIVAPTFVYLESDAAGGAVIKQELGTDVPYFSVNVELGPSGVEKILPIGKVTAYEKSLFAGALSELETNIKTGVSFIDGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G900</accession>
    <name>M5G900_DACPD</name>
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        <submittedName>
            <fullName evidence="1">NADP-binding protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_103678</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <sequence length="247" mass="27566" checksum="6A10B9C4DC0152AB" modified="2013-05-29" version="1">MSSVSYFVTGASRGLGLEFVTQLLARPNTKVVATARDPTALPELAALQRCTPSDRLLVLQYDVTDFRFSERVVEESSKFLENKLDVLIANAGTVFQRGVGFQERNWDKAIETLTVNAVASFVLLQALLPLMKNAQRRTVLFISSRQASFELTQHSPKSVVPLDSWYPDYNVSKAALNMAILKFGQELKDDGFILVPMSPGWVRTRGGGDDAPLTLHESIRGMLEYLDRVTLNDTTKFVDYQGNAMPW</sequence>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="13"/>
            <end position="58"/>
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        <location>
            <position position="1"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU04785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="60" mass="6345" checksum="6957E54E8820A30D" modified="2013-05-29" version="1" fragment="single">HTDSLSATIHATITDGVAIGHPCCGVHNCHTPLTFTHNHFCSQHQDLNAVCAVTGCHLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9A7</accession>
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            <fullName evidence="7">Tubulin nucleotide-binding domain-like protein</fullName>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the misato family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627270.1">
        <property type="nucleotide sequence ID" value="XM_040768811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9A7"/>
    <dbReference type="STRING" id="1858805.M5G9A7"/>
    <dbReference type="GeneID" id="63683873"/>
    <dbReference type="HOGENOM" id="CLU_022511_2_0_1"/>
    <dbReference type="OMA" id="QMYANES"/>
    <dbReference type="OrthoDB" id="271881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="6">
        <location>
            <begin position="142"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="51457" checksum="988D826ADE388868" modified="2013-05-29" version="1">MHEIIYVQSGTYANYIGQHFWNVQESYFDWEEEPEEVNERKPPEVNHDISFREGLGTNGVSTYLPRVLIFDSKDVFGSIPKYNTMYESVAGEEANDSASWTGQSVSYQQPLHPKSQYQCDLDEQTTKASQTIESRRTYNPSTWADYTSVYYHPCSIWPVSYILTGTGNKWDEGEDAWGRLQHENDFWDKDFRLFAEECDLLQGLQATSSASDAFASLSASLLQTFRDEYPKLPALLFLPLSQRKEKFNPYDLAERRRLSTESKMLVMSAEAEATIIPLQCPATWSKGQWTTELALDLNFGEAYQSSALLSAHIESATLSLRLNSNPTSLSSLTSLLNYHTDTPISHLSGALPLYDTLFTNKIYDFSTVLDASVPDTPTFSACTTYRGLLSPQTRVNLTERLEQSIGIREPLLQLFIVLCPTISYFDFIPSYSGNSFEQCTAAVYVAHNLSHIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9D5</accession>
    <name>M5G9D5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627300.1">
        <property type="nucleotide sequence ID" value="XM_040767502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9D5"/>
    <dbReference type="STRING" id="1858805.M5G9D5"/>
    <dbReference type="GeneID" id="63682564"/>
    <dbReference type="HOGENOM" id="CLU_1331921_0_0_1"/>
    <dbReference type="OrthoDB" id="3357029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="23464" checksum="950731E7DC880AA2" modified="2013-05-29" version="1">MEKEDGSERLRLTGVTPTSPSFRHDPSAEEGREAHSARGVRIRTIATLAFLPVLLAIALLLVFALWFFTRSTTTVEQVWQHGVFLLNEGDDGQESNMTGLTISSILSQAISLVSPWVLSLFAYRIAVLWTRDIQRHHYCDRRARRRVLPNPYEHIWLACVAPLVTKPDHVWHCQSPAVHPRTTSPSCCGCPFLFLRVFYLPCRRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9E2</accession>
    <name>M5G9E2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632303.1">
        <property type="nucleotide sequence ID" value="XM_040771720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9E2"/>
    <dbReference type="GeneID" id="63686782"/>
    <dbReference type="HOGENOM" id="CLU_103874_2_0_1"/>
    <dbReference type="OMA" id="ATRREDM"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22370" checksum="5B07A223BB124CC1" modified="2013-05-29" version="1">MNRLGQLANSSRGDTPEPGLQQGHRNTFGTSHGRTVNVQLLDDEGDLTLEFETCLAFIFSKYCTPEPTTQPLDWLSASGPDRPAPPPLDWIQKGAYISDEALDRWAIDTNGAPLSEAVKEEIKDSIDTDDDGHLTFAGMLQIYQLQTSMDEEETWRDLASHGFDRNLELAPTRREDLQEPPADEHAPREDNEIHNPENTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9N6</accession>
    <name>M5G9N6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631884.1">
        <property type="nucleotide sequence ID" value="XM_040767993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9N6"/>
    <dbReference type="GeneID" id="63683055"/>
    <dbReference type="HOGENOM" id="CLU_1077775_0_0_1"/>
    <dbReference type="OrthoDB" id="10067381at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="Bles03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28962" checksum="22A17ED9EEC26312" modified="2013-05-29" version="1">MEIQPSDSSTGLHGKHELREEIREQTVLGLRRLCENTGLTSGKWVFFVHRRSVTWVWKKIALSLVQGDLKETPAFAAKVSTINVGHTHIICLFLPDIFDKDAVGQVLDVLTTKVQVIPVVVKPDLYTYIGLYTKHPSGIRPSLWQVKDFVSPDSVTGLIGSSAVRCKSVTKKKQEPERQPDGLDCRMEDENAIEAYCSMNGLGPLRSWYPGSSSWQGKRGKNAASWHETDDEEQPNLNLARQSSDIVRVSWDESEIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9P2</accession>
    <name>M5G9P2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629481.1">
        <property type="nucleotide sequence ID" value="XM_040770044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9P2"/>
    <dbReference type="STRING" id="1858805.M5G9P2"/>
    <dbReference type="GeneID" id="63685106"/>
    <dbReference type="HOGENOM" id="CLU_794579_0_0_1"/>
    <dbReference type="OrthoDB" id="2884925at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="349" mass="39735" checksum="CB041A3A24D10978" modified="2013-05-29" version="1">MRLLEASPRSEIVRYTPAIGRLPTELLQEIFLFAVDDDDKHKHTKWVVSHVCRHWRHVATHYPRLWSRMRFDPTTRLGSRRLLQAASQMAQAVDLDICMTWSATSSNWAGRREKANFIALALSRRSQWKSLVITDNEFGVESNLAVLAEGVRHAALPRLKSVQYHTTRNGGEGHRVFELVTSASNLEVLNLRNVDFMGRRVPERLRILRLDNCNLRTIDALYEMLALVPNLKVLHISIPCPTPAYTSTTTHNLFPCYSFACSPWDYGHIHTTPGLCGSWLLRTWAPSIYGPLETLVLTACPSTQLKGEQKLATRRFLKRLQPGAGKFRRSMFLNCLALHYLSCGLCNPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA40</accession>
    <name>M5GA40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627620.1">
        <property type="nucleotide sequence ID" value="XM_040773086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA40"/>
    <dbReference type="STRING" id="1858805.M5GA40"/>
    <dbReference type="GeneID" id="63688148"/>
    <dbReference type="HOGENOM" id="CLU_733660_0_0_1"/>
    <dbReference type="OMA" id="ISHAMGM"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001423">
        <property type="entry name" value="Ras family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="175"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="377" mass="39739" checksum="C6E9312AF3710374" modified="2013-05-29" version="1">MATAAQAAALGLEHWKVTMLGDGGVGKTALAVQFTQKQFIETYDPTIEDSYRKQVLADGKMSFLEIIDTAGQEDYSTLREQWIREGQGFILVYSVTNQTSFQNVDRFRKTMISLHPEIPVFLIIGNKADDAYRREVSAEQGLTYARRHNCEFFEASAKSGQNVEKLFSEVVRQLRANNRSPQPLTPNSTTSTSGRGSSRTSASGYTAHSSTVGTATPLTVPSSGSLGHQQTPRGYPAASGAGGLGAPRSPPPPSSVGKMSAPPALGPGMSASGSTRNRGGSTSRSEPAAYPIPGRDVRSPTAAGGMPMSPPAPKKGASSAPAPAVRGGTRLQVNTSFITGNAAKSFFFKTGSAGGARGKQKEKEKEEEKSKGGCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA0</accession>
    <name>M5GAA0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627715.1">
        <property type="nucleotide sequence ID" value="XM_040773118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA0"/>
    <dbReference type="STRING" id="1858805.M5GAA0"/>
    <dbReference type="GeneID" id="63688180"/>
    <dbReference type="HOGENOM" id="CLU_013871_2_2_1"/>
    <dbReference type="OMA" id="NIWISGA"/>
    <dbReference type="OrthoDB" id="3250441at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="491" mass="55182" checksum="645AB72A06385120" modified="2013-05-29" version="1">MSICIVERRSAALSEHRDDELGENRREAGAEVEPSTVQEIFERAVSFGRKANAPSKAAVPREWRYEQITGPILTGRPANCLGHPIGIYAPIFEIFKSSLCKRNFDSITPKEYSLAHMLIHEANEIYTNANDRSALIQDVMDSLLDKVLHWTSDDDRTVACDCIRVRVGDDEGLQTEIAFFVHRVEVSMGDSEVNNYIAATARRMWVQRGRKNLRNVSCSPSFLIVIAGPFIRVSGIVFAGEPTTEALKNFISLEVNSYPLEARICEVAHLFRCLKESIASLELFYQRVTPSQTSMLSARLPDTTSLPLDGHQLVFQDILVQGDDGRTRPLFRTEFDSKRCVVKFSHTYGVEAHELLAKAGLAPALFHAKQVYHDSFWLIVMDHVDGKPFVEVPSEGKDSVLNDLSRAVQHLAASGLVHGDLRELNIMCVKEDKTWRARLVDFEWSGGAGKARYPVSLNDTGEIGWHSSVKRDGFLERAHDEHMLKRLMSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAD8</accession>
    <name>M5GAD8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629806.1">
        <property type="nucleotide sequence ID" value="XM_040772569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAD8"/>
    <dbReference type="GeneID" id="63687631"/>
    <dbReference type="HOGENOM" id="CLU_1758741_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="16817" checksum="E5C599A2AD8BAC88" modified="2013-05-29" version="1">MYNFTELTSKYGPNSAGTLSRRLATEILQGPQSSFGPFSLLRLITKSCYFEQSLMVTISLSKTNKSSPSLLPFLSVPTRFLKKSSGSLRGIPAAVFRLLFGSRLYSMNRPTWSLGFSHRTKNNWRWWTKEESWTKEESTTTRPAPLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB67</accession>
    <name>M5GB67_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_115471</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630161.1">
        <property type="nucleotide sequence ID" value="XM_040770009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB67"/>
    <dbReference type="STRING" id="1858805.M5GB67"/>
    <dbReference type="GeneID" id="63685071"/>
    <dbReference type="HOGENOM" id="CLU_093932_0_1_1"/>
    <dbReference type="OMA" id="DTSMVLF"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="14">
        <location>
            <begin position="75"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="11">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU03267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="121" mass="13808" checksum="2908A358FFAB998E" modified="2013-05-29" version="1">MASDESIQFCIECNNLLYPRADKDRHVLLYACRNCDFEYQATDPCVYKNDLFTVTKEQSGVTEDVNKDITLPRDADVLCPSCHSEGAVTYQDQGKRKETRMTLFFICLKCGHAFVDPNVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC57</accession>
    <name>M5GC57_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CNDP dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_22682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628515.1">
        <property type="nucleotide sequence ID" value="XM_040772924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC57"/>
    <dbReference type="STRING" id="1858805.M5GC57"/>
    <dbReference type="GeneID" id="63687986"/>
    <dbReference type="HOGENOM" id="CLU_029469_3_0_1"/>
    <dbReference type="OMA" id="CNVKFMI"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="10">
        <location>
            <begin position="209"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="475" mass="52519" checksum="FD53D85461746117" modified="2013-05-29" version="1">MPAPTEFIKYVDAHKDAFIARLGEAVAIPSVSGDPSHRQDVINMAGFIKRLLEPLGVKVELKDIGMEKQTDGSELPLPPVVFGVLGDNPNKKTILLYAHYDVQPALVTDGWNTDPFTLSPDNEGRLFGRGSTDDKGPLIAWINIIEAHVKLGLELPVNLRFCFEGMEESGSEGLDDLIIREKNGFFESCDCVCICDNYWMNDRTPCLTYGVRGMSYYRLVVSGPARDLHSGLFGNTVHEPMTDLILLMSKLVTPNGEILIPGLDKLVAPLTDTERKRYETLDFALTDIEDQVGAKIVLSDDKARVLMGRMRNPSLSLHGIEGAFYGPGAKTVIPAKVQGKFSIRLVPNMTPENVDPLVVKYLHDEFAKLKSKNTLKVENIHGGKPWMADPDHWNYRAAIKATEKVYKKKPDLTREGGSIPVTLTFADVLGLNVLLLPMGRGDDGAHSTNEKLDTYNYIEGTKLLGTYLHEIAVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC98</accession>
    <name>M5GC98_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633553.1">
        <property type="nucleotide sequence ID" value="XM_040767788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC98"/>
    <dbReference type="STRING" id="1858805.M5GC98"/>
    <dbReference type="GeneID" id="63682850"/>
    <dbReference type="HOGENOM" id="CLU_2346636_0_0_1"/>
    <dbReference type="OrthoDB" id="3366943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="97" mass="10869" checksum="F07C1D67443E444E" modified="2013-05-29" version="1">MPPARELQISTAACLKVVIRECAPRTGEWKERVLYGLLKAWVEVSGIFNKDQDTLTLLASLKEVWDELLVACPTIPQVEAAQLQTLDKRMFQALVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCC0</accession>
    <name>M5GCC0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_49640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630681.1">
        <property type="nucleotide sequence ID" value="XM_040774921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCC0"/>
    <dbReference type="STRING" id="1858805.M5GCC0"/>
    <dbReference type="GeneID" id="63689983"/>
    <dbReference type="HOGENOM" id="CLU_007149_4_2_1"/>
    <dbReference type="OMA" id="AAKWQES"/>
    <dbReference type="OrthoDB" id="5581181at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044554">
        <property type="entry name" value="ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014786">
        <property type="entry name" value="ANAPC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057975">
        <property type="entry name" value="TPR_ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08672">
        <property type="entry name" value="ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25773">
        <property type="entry name" value="TPR_ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01013">
        <property type="entry name" value="APC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="263"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="598" mass="69014" checksum="F317F4CA878DB6A2" modified="2013-05-29" version="1">MKHARGEFIALFRARWLACLPPSFTLGLRLFLRTTLQTLSAHEKLFHILVQLGISERFDKTFIDVMYDELEQKILDSCPGIWREPRLEMIRKAAKELEERWLSAVYGHRFSRTENNDWFKNAMMMVTGRLDHFISRTLVELRTSEIFDIVVDFPDTLPAIQDLRVCCPFLFPLSWLPGSLVTRVNQRILQPAADTDDIITFYVSLIRCLRIIDPQGVILHKVAPPIRKYLRDRPDAVRCIVKRMTDENESFMQEGEQVVPIQQVHEAYDDYTDPHWLPEPVDAGADFRTTRPMDIVSTLVSIYDTQDLFIKELQHLLAGRLLAVRNSPLDDEIRNVEMLKMRFGEAPLQVCAVMLKDMSDSRRTNTHLHGEQSHPLYTTVISRLFWPTIQPVPLKMPGQFKELQDGFEAEFHKFKPDKSLKWVPQLGAVSLNLELEDRVVEVEATPIQAGVIELFSERDTWDLEQLMQKLGGIDRVLVQSALDFWIGEGVVKNEGSRYILLEKAEAAKGVSQRPPPVDEAPRVDERDKQQAEQMKIYWQFIQGMLTNLSSLPIDRIQAMLKFAPGYNRSVQELAVFLESARKEGLVVFTNGAWKLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN6</accession>
    <name>M5GCN6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">20S-pre-rRNA D-site endonuclease NOB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_113046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NOB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633219.1">
        <property type="nucleotide sequence ID" value="XM_040769550.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:maturation of SSU-rRNA"/>
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        <property type="entry name" value="20S-pre-rRNA D-site endonuclease NOB1"/>
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        <property type="entry name" value="5'-nuclease"/>
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        <property type="entry name" value="Nin one binding (NOB1), Zn-ribbon-like"/>
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        <property type="entry name" value="NOB1"/>
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        <property type="entry name" value="NOB1_Zf-like_sf"/>
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        <property type="entry name" value="NOB1_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08772">
        <property type="entry name" value="Zn_ribbon_NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037125">
        <property type="entry name" value="D-site_20S_pre-rRNA_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144206">
        <property type="entry name" value="NOB1 zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ribonuclease PIN" evidence="11">
        <location>
            <begin position="17"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Nin one binding (NOB1) Zn-ribbon-like" evidence="10">
        <location>
            <begin position="283"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="183"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="407"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037125-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="460" mass="50148" checksum="FDDC2C864A048732" modified="2013-05-29" version="1">MTTPANASTSKPRIKHLVLDAGPLLTFTPLRGLAENYYTTPQIVEELKDPRAREHFQNLSLTAGVHLQVRQPDILSVSQVTITAKKTGDYAVLSQADVGVIALTHELATEETTNNAIESQILSNECGLHGAENVGVLAEDDGPQNADEANSGASSEEEEEDEENTDDALEGTEDIQGQMENLHIEGETSRRTKPESSDPLPSDDAPAPTVVDVDDPPSDDGEGEWITPSNVDSYKSRAREPNASGTKADNRPMIVACMTADYAVQNVLMHMHLNLVTMEGKRITKVKSWVLRCHACFKICKDPTKKFCPSCGNPTLLRTSVSTEAPSPGSPNQEPIFRVHLKPNFQYRTRGTIYSIPLPKLGQAKGGGTGGSGLILREDQIEYQRALHKEKGRQAKEERAMERAMAAAAKGERPRGQGTWDDPDWIPGLLLGEAGRKRGGGMPAVGHGRRNPNEARRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDD5</accession>
    <name>M5GDD5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_51612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629185.1">
        <property type="nucleotide sequence ID" value="XM_040775048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDD5"/>
    <dbReference type="STRING" id="1858805.M5GDD5"/>
    <dbReference type="GeneID" id="63690110"/>
    <dbReference type="HOGENOM" id="CLU_012062_15_7_1"/>
    <dbReference type="OMA" id="PAKGCRV"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000145">
        <property type="entry name" value="Putative RNP domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF64">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="157"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="218" mass="23498" checksum="2DD27BB7A36C399A" modified="2013-05-29" version="1">MATARAAASGSGVRSPNGRDTRTQLYVGNLPYRVRWQDLKDLFRKAGTVLRADVSLGSDNRSRGYGTVLLATAEDAGRAIDMFNGYVWQTRTLEVRPDRLPPPDPEHQNPAAGPSPLHAMPYVPPTNLAPPGPGPGPIAHGPWLNIDGSPARPQSALPFHVQWQDLKDHFRSAGQIARADVATGPDGRSRGFGTVLFVHESDALAAVEMFNGFVVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDL5</accession>
    <name>M5GDL5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">FMN-linked oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_65633</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629407.1">
        <property type="nucleotide sequence ID" value="XM_040775792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDL5"/>
    <dbReference type="STRING" id="1858805.M5GDL5"/>
    <dbReference type="GeneID" id="63690854"/>
    <dbReference type="HOGENOM" id="CLU_013299_3_1_1"/>
    <dbReference type="OMA" id="CRTRNQR"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="10">
        <location>
            <begin position="46"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="418" mass="45610" checksum="637387E13D736C84" modified="2013-05-29" version="1">MRHTPPTRSPTPDAKRTCTEIPSDKAGPSTSSWTRHPVHYGKGIHLAPMVRSGTMPTRLLALEAGAELVWTPETVDRAIIGCERRVDPKTGVITYIKSHKPVLTLHPVERPRLIFQLGSANPDLAAEAAKIIYQDVAGIDLNCGCPKHFSVHAGMGAGLLLDPDKLCAILQAIRASIPPEVPVSCKIRMLPSQEDTLSLVRQIADTGTINCLTVHCRTPPMRDREPAMKHRLKDIVQSVGKKVVVVENGDCVGYESAQQILQQTTARAVMIARAAEANPTCFLPDGPKDAETYLIPRYVRLAKYLDHHWSNTKFCLAQFTSPDPHLGKHGRLEWKKAINGAKSYEELRLLWGKEAGFFEGGEEILAGIQHALRARGRSAPELGVLSTPGPALSQQSASSVIDPAPPDPILVREIQAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDL7</accession>
    <name>M5GDL7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Uridine kinase</fullName>
            <ecNumber evidence="11">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_93118</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="11"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631526.1">
        <property type="nucleotide sequence ID" value="XM_040777126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDL7"/>
    <dbReference type="STRING" id="1858805.M5GDL7"/>
    <dbReference type="GeneID" id="63692188"/>
    <dbReference type="HOGENOM" id="CLU_021278_0_3_1"/>
    <dbReference type="OMA" id="EPQLHCE"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043771">
        <property type="term" value="F:cytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002070">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="13">
        <location>
            <begin position="37"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="14">
        <location>
            <begin position="274"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="55460" checksum="54D8E0EDC40E679A" modified="2013-05-29" version="1">MLPTTQGAPTHKNHILTSHGRPPWYGPDGLPIHNAFVIGIAGGSASGKTYVAEKIIQSLQSLPSILILSQDSFYKKHNEQELALAFSNEYDFDHPSSIDMELFAQCLKDLKEYKQTHIPIYSFVHHQRLPETKYLYGASVIIVEGIMTLLDPALRDLYDLKIFVQCDSDLMLARRLRRDIQQRGRSVDDVLKQYLRFVKPAFDNFVGPSAKYADVIIPGAANTVAIDLVVNHIRRKLAERHASFRSELSRAQPAIEQGWDAEVSKWPGVVLLRQTPQLKGIHTILRDETTSREDFIFFADRLATLVVECGMDLLPYVPHSVQTPTDAIAHGLKLTAHVCGVSIIRAGGPLQAGLQRVLRDVPLGALLIQSDPSTGEPLLLHTSLPCYILHREQAKDTWVFLLDSQIGTGAAALMAIRVLLDHGVQEEHIIFLTFLISQQGGPNVLRKAFPGVRIVTSAVDELLLMAWSDVDWETGERRRVWKIVPGMGHIGDRYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDW0</accession>
    <name>M5GDW0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629627.1">
        <property type="nucleotide sequence ID" value="XM_040772518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDW0"/>
    <dbReference type="GeneID" id="63687580"/>
    <dbReference type="HOGENOM" id="CLU_2793926_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="68" mass="7846" checksum="E26277B149283AAF" modified="2013-05-29" version="1">MGVLEDEAKRIPSNKKNRAVVRWARPKKRVSVVDARLPMDNHILRSSRNIEPKQKSITDEKKASSHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDY2</accession>
    <name>M5GDY2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calnexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_21754</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the calreticulin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629692.1">
        <property type="nucleotide sequence ID" value="XM_040772536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDY2"/>
    <dbReference type="STRING" id="1858805.M5GDY2"/>
    <dbReference type="GeneID" id="63687598"/>
    <dbReference type="HOGENOM" id="CLU_018224_1_2_1"/>
    <dbReference type="OMA" id="SGCGKWE"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000001">
        <property type="entry name" value="Calnexin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000011">
        <property type="entry name" value="Probable calnexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140976" description="Calnexin" evidence="9">
        <location>
            <begin position="20"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="509"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="58544" checksum="2A8C9A2273B03BCF" modified="2013-05-29" version="1">MRAVALSTAVLIAASAVVAQDKPVFEATTIKAPFLEQFTDDYSERWTPSEATVQTPVGGETYSYVGKWALEEPTTPLFSGDKGLVAKTKAGHHAISAPFAEAVDPKGKTLVVQYEVKYQKGGNCGGGYIKLLEEGFQTSGKDFNDKTPWVIMFGPDLTCPGTKVHFIFRHKNPITGVVEEKHLKKAPKPIIGTETKLYTLIVNPDNTYEILIDGKSEVSGSLLEDFDPAVNPPKEIDDPSDIKPEDWVDAARIPDPEATKPEDWDEDAPAQILDEEAEMPEGWLEDEPVKVADPDAEKPEEWDDEEDGDWVPPMVDNPKCMVAPGCGPWKRPFKANPAYKGKWAAPMIDNPAYKGLWAPRKIDNPDYFEDLQPSDLNKIGAVGIELWTMTEDILFDNIYVGHSVADAKELAAETFDVKHGIEEAAKAKAKAEETAAAEGPASSWKDDPVAFIRAQVTKFIDLAIIDPVAAFKAMPEVGGALVATALTLLGLLAAISGLVGGSSKPVIKATKPAQKEKAPVAPAGEQKKEESAAKKRTVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE74</accession>
    <name>M5GE74_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_113333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632036.1">
        <property type="nucleotide sequence ID" value="XM_040769611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE74"/>
    <dbReference type="STRING" id="1858805.M5GE74"/>
    <dbReference type="GeneID" id="63684673"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OMA" id="HVEEYMK"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="8"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="308" mass="33601" checksum="0D6F7C874D41622D" modified="2013-05-29" version="1">MSYPYQQKPTIAVCGATGLQGGSVVRFLLQDGAFHVRALTRDVTSPAALQLAANGAEVVRCDYNDVPSIHAAFSGCYGVFGVTSSWESGPDAERQQGYNLVYCAKAEGIRHFIWSTLERAAFPIPHRDSKDDIDSYLRSSGVPFTSLVAAMTFESMADSTVLKPSRGGLVGEWAIPTDSGIPCFCAADTGGFVSAVLKNPQSWLGQTLTMITDFVSPRQYFQLLGDASRKVIRASELSLEQFNRIPNMPQPPVPKEFWLNIKHLINNPTWPTAQIATCRALFPNAISLRAWIYNNQSALLFAATNPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEA8</accession>
    <name>M5GEA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632126.1">
        <property type="nucleotide sequence ID" value="XM_040767808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEA8"/>
    <dbReference type="STRING" id="1858805.M5GEA8"/>
    <dbReference type="GeneID" id="63682870"/>
    <dbReference type="HOGENOM" id="CLU_1337473_0_0_1"/>
    <dbReference type="OrthoDB" id="2832083at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="23109" checksum="5B15B3820E947173" modified="2013-05-29" version="1">MSWLAWPFSKVLLADCTPSPDVQELEIIGAGLSRTGTVSLHTALTILGFGPCHHGAVHFFYPERSVAFTKALKGEPTDYRALMRGYRSIVGAPLCSLVPELLSTFPKAKAILTLRDTPEQWWTSMMATVPPMSFPLYRWSVYPIRYLGVWNQLVRTMLEERWDLLYGRGRRVGIENYTRHEAYIRLGTVVHVLGRAGAGDTLPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEJ1</accession>
    <name>M5GEJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional coregulator SSA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_46241</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Transcriptional coregulator that functions together with transcription factor HSF1. Positively regulates the expression of laccase LAC1 during glucose starvation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with transcription factor HSF1 on chromatin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632356.1">
        <property type="nucleotide sequence ID" value="XM_040774690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEJ1"/>
    <dbReference type="STRING" id="1858805.M5GEJ1"/>
    <dbReference type="GeneID" id="63689752"/>
    <dbReference type="HOGENOM" id="CLU_005965_3_0_1"/>
    <dbReference type="OMA" id="AYTKNQD"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000016">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="612"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00058890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00062310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="648" mass="70502" checksum="085C20503D314FFB" modified="2013-05-29" version="1">MTSKAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVSFSDTERLIGDAAKNQVAMNPHNTVFDAKRLIGRKFDDAEVQADLKHFPFKVISVGGKPIVQVEFRGETKTFSPEEISSMVLLKMKETAESYLGQTITNAVVTVPAYFNDSQRQATKDAGVISGLNVLRIINEPTAAAIAYGLDKKTQGERNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFKRKYKKDLSSNARSLRRLRTACERAKRTLSSAAQTSIEIDSLFEGIDFYTSITRARFEELCQDLFRSTLEPVEKVLRDSKIDKANVHEIVLVGGSTRIPRIIKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILSGDTSEKTQDLLLLDVSPLSLGIETAGGVMTPLIKRNTTVPTKKSEIFSTYADNQPGVLIQVYEGERARTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSASDKTTGKSNRITITNDKGRLSKEEIERMVADAEKYKAEDEAAALRISAKNGLESYAYNLRNSLTDDKLASKFDAGDKAKLQEAVDECIKWLDASQEGSKEEYEERQKDLETIANPIMQRLYAQAGGAPGGAPGGFPGAGAGPGGAPGGFADEPSVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEM1</accession>
    <name>M5GEM1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Crm1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_19979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632426.1">
        <property type="nucleotide sequence ID" value="XM_040771748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEM1"/>
    <dbReference type="STRING" id="1858805.M5GEM1"/>
    <dbReference type="GeneID" id="63686810"/>
    <dbReference type="HOGENOM" id="CLU_011906_0_0_1"/>
    <dbReference type="OMA" id="WAFKHNN"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000022">
        <property type="entry name" value="protein EXPORTIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="34"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1064" mass="121600" checksum="9D4C6F446CE2C796" modified="2013-05-29" version="1">MDGILDFEHEFDVNLFDRVIYALFNGSGAEQAEAQRVLTLFQEHPSAWQRVPYILSTTTNQHAQYLCCNILDKLIQTRWKALSVEHRQDIRSFITTVIIATSESEEKLRRERLYLHKLNLLLVQILKQDWPKDWPDFLPMIVQSSRQNLNMCENNMQILRLLSEEIFDYSAEQMTQQKTRNLKQQMCGEFGQIFELCQEVLQRSTKGSLVRATLETLLRFLNWIPLGYIFETQLIDSLITRFLEVPEFRNITLKCLSEIAGLHITAEYNRHFVHLFTQTMSSMNRMIPPTTDIAAAYSTSTDAGQDLVFNFTQFLTGYLTAHGRLLENPENAAVLTNAHGYLIKLSQVDEREVFKMCLEYWGKLVSELYDEMTALPLRDGTAAFGALSLGGPPVIGQISGRRALYDQILSQLRLVMIEKMVKPEEVLIVENEEGEIVREVMKETDTIALYKSIREVLIYLTHLDVMDTENVLTEKLAKQVDGSEWSWNNLNTLCWAIGSISGSMDEETEKRFLVTVIKDLLGLCEMKRGKDNKAVVASNIMYIVGQYPRFLKAHWKFLKTVVNKLFEFMHEMHEGVQEMACDTFIKIAQKCRRHFILQQPGETEPFIDEILRTIYRITNDLKEAQMHTFYEALGYMIASQPNKNTQDALIRQMMESPNQAWTGEMQLARQGINIVVDPEHAKVLSNVLKTNVAVCVSLGSFYWTQLTYIWNDLLAVYRAASSAISEAVATGGPQAVHMQNVRTCRTVKKDVLRLIDTFIRKAEDLDQVNRTLVPQLFEAVLSDYREVLPAARDAEVINVVHTVVSRLGNGAVDYIPGIIESIFEPTLAMISENETDFPEQRLAVFKLLRAIDAYSFEGLLKLQPSSLYNVLNSIGFAFKHMQRDVAEVGLSICLDAINNFSGASADISNAFFTSYYMTILGDILQVLSDSDHKSGFKGQCGVLQRLIQLVIANEIHTPLFDSSQIPAKTNEEFVRNQLTTMLKSAFGHMSPIQIEQFVQNLWDFSADGARFKLAVRDFLITLKEFAGDNAELYREDKEMEVQKQRELQMRVPGMVKNDSMDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GET1</accession>
    <name>M5GET1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632551.1">
        <property type="nucleotide sequence ID" value="XM_040769684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GET1"/>
    <dbReference type="GeneID" id="63684746"/>
    <dbReference type="HOGENOM" id="CLU_645606_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067805" evidence="2">
        <location>
            <begin position="17"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="43617" checksum="CFC1573A0ED3FAC2" modified="2013-05-29" version="1">MQPYALLSLLAASALALPSGHVSDAYERSIVNDISIPAPVNGTVNQIASQMSSTMNGTFSKGTSSAPNVPRGQGKAYRSYDIALAPAVGPNVSVPVDPTGVPQTGVSTANNTAQGIKPKLPARQVPVNPTGVPMTGATMANSTVQGVKQALPVDPTSVPATGLETVSGIVQGIEQKLPVRQLSVDPTVIPITGLTTANSTVQGAEQKLPVDPTTIPKIVVSTMNGTAQGIEGKLPVRQVPVNATSVPMTGVTAANSPAQGVEQKLPVDPTGVPEGGLAAANSTAGGTRQRLPLARQPPVDPLQIAQTGVTTIDNTAQGIKQELPVDPTSVPMTGLATVNGLAQGAKDKLPAREAPAVNPAEVLNEVKNHAPRSPQNLDSPGVDVNTSPSGENVDFYGPSLSHRSYIEQLARDVVTKIVRDLDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF12</accession>
    <name>M5GF12_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630632.1">
        <property type="nucleotide sequence ID" value="XM_040769929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF12"/>
    <dbReference type="STRING" id="1858805.M5GF12"/>
    <dbReference type="GeneID" id="63684991"/>
    <dbReference type="HOGENOM" id="CLU_077732_1_1_1"/>
    <dbReference type="OMA" id="MARAVHK"/>
    <dbReference type="OrthoDB" id="337486at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21369" checksum="BF41CE24E4675D00" modified="2013-05-29" version="1">MAPTRRASSGRPSPAPYVQQKLSFGSSKPAASATTNKAKKSASTTASRKQTETPPSSVQAPELVEPEESSDEEVDEAATPTLPAAQLEPVKRETLDVNDKSGKYRSYWKEAQTRMGHQEPIHGKDESKVYGMLRVFDLSYEYGPCIGISRIERWTRAEVMGLEPPTEIRDILMTEEGTNDPRLAQCIYFESDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF26</accession>
    <name>M5GF26_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_21223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630667.1">
        <property type="nucleotide sequence ID" value="XM_040772299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF26"/>
    <dbReference type="STRING" id="1858805.M5GF26"/>
    <dbReference type="GeneID" id="63687361"/>
    <dbReference type="HOGENOM" id="CLU_007625_1_1_1"/>
    <dbReference type="OrthoDB" id="300289at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:vesicle-mediated transport"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
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        <property type="entry name" value="VPS9 domain"/>
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        <property type="entry name" value="DUF5601"/>
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        <property type="entry name" value="UBA-like_sf"/>
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    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
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    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="296"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="645"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="170"/>
            <end position="183"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU03773.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="690" mass="74901" checksum="8642FFA493C66424" modified="2013-05-29" version="1">MSTEEGTSTPTETHPVEASDNEEENPWSSSSAEAPDSSEARAVDGAPEPPLEIADEPEPSHPKPLEQSTLDEFDPLADTAADAWRHAEGHLPVGVEASASGPEIRFTQEPDTTLDEPPQSRAQAQTPLSGVSTDFPHSPSSPPGVPSPTTLASLAQPLRRASQHELGETEASSSQQTNGNAMDTSGPKVTPPFDFQKFLDQMKSKSAEPVAKYLRSFLHNFQKRTFPVTDQVKLIHDFLAFIAARMSECEVWKNLPVEQFDNATEAMEKLVMNRLYHLAFTPAIDRNIYPITTDDLERDHVLSQRIRLFEWVTEEHLDIPTGEGSKGFIMFAEQELLKINHYKAPRDKLICILNCCKVIFGLIRHLNREEGADAFIPILIYVVLQANPDHLLSNVEYISRFRSATKLQSEAGYYLSSLMGAVSFIETMDHTSLSNISQEEFEANVEEAVTRLSPSSSPGPMTPQRARPPAPEVTTAEVTASAAAGEESARPLLLPTTLAEDTKKFFQRTGDFAQQTISKPLNAIGRIFSEALEEPPGVVGRALDAASNWVQPNPVTPAPPPKDQSAPLPAPYKPRVRQSPSRPNSGASTPIGTPTRVGGTLQPFPSPLGIPPVSTPRTATPDHDGDEAFDFAALSAEIDRAHDAAQASGRDTLLQIFPGLDGELADVVLEATNGDLGLSIDKLLEMGVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFG4</accession>
    <name>M5GFG4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040767726.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="376" mass="41387" checksum="2B386DA84797FFDC" modified="2013-05-29" version="1">MAKPSTHKSATKPVPPKDEHTMLKTATAIIACMCEDAEDPRFLPLVKYPDVAPFGNVVALLLNSPQFTLVRNLPEKWVQLFALDQQEELAALSVPPKEEEEEEEEEEEKKFKVMLSGFSTSLGSLASPLMKAEKGKAKAKETMPAKLVMLRLDDGVDKMPPAIRVHGRLMKEDSCNVGWMPEETLVKVLLAMTDAAVLESFAAENCCMLCRKHAIGKDGKARHECDIAEVANRAVCSTCKAAKKPCSTHTVHLTKGMALPPASVEDLFIPETPEPEPAEETAKEPAKKKKQKPVHSYALVKPKKHEQEDNKDSVGPSTKQSCLPEAEVKPPVTPLCMAEHKMLKLQKSLHTAQKAMDMVMGWVDQVQTLLGRALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG45</accession>
    <name>M5GG45_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_47785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMEM41 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG45"/>
    <dbReference type="STRING" id="1858805.M5GG45"/>
    <dbReference type="GeneID" id="63689845"/>
    <dbReference type="HOGENOM" id="CLU_038944_1_0_1"/>
    <dbReference type="OMA" id="CYVITYL"/>
    <dbReference type="OrthoDB" id="3364966at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF18">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="97"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="41802" checksum="0E824D618B9E2DF4" modified="2013-05-29" version="1">MPISATPATLRQKRPLLNAALKLAVVFVISTLVLGGTLYLAMPPLDPEDRPLLHLPKSFQDLKALDFLLKKYKRMYPFRTVLCFVVVYLFDQAFSLPGSMYLSILSGAVWNPFFAVPLCCFCVATGSALCYLLSAALGPALLAMPKWAERVERFRVTLESQKANLFSFLIILRIAPLPPHWVTNILCPHLGVPLPFFWLSAFLGILAPTVIQVTIGGGLEQMTSPKDFHLLSPRNVLSLGAIVVAALVPVVLRWAFKDRVDAVAEVEATADVAAHGPRSPTISIGIRSPTVSVRPLSPYHDQPASPRSHVSAEPGIVWPPKGNSLLVLLKDDDDVVEVEEEDEDGHKVAVAGGVAMPEDQQGQGSRWRWLNGWWHEGVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG98</accession>
    <name>M5GG98_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">(2E,6E)-farnesyl diphosphate synthase</fullName>
            <ecNumber evidence="6">2.5.1.1</ecNumber>
            <ecNumber evidence="5">2.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dimethylallyltranstransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Farnesyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Geranyltranstransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_20653</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.1" evidence="6"/>
    <dbReference type="EC" id="2.5.1.10" evidence="5"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632007.1">
        <property type="nucleotide sequence ID" value="XM_040772021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG98"/>
    <dbReference type="STRING" id="1858805.M5GG98"/>
    <dbReference type="GeneID" id="63687083"/>
    <dbReference type="HOGENOM" id="CLU_028376_1_0_1"/>
    <dbReference type="OMA" id="CSWVVNQ"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000006">
        <property type="entry name" value="Farnesyl pyrophosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU05113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="40214" checksum="BE47B870EA2E3738" modified="2013-05-29" version="1">MAALTNGQDRRARFTAVFPKLQKELIEFVIAQGFPQEALSWFQRNLEYNAPGGKLNRGMSVVDTLEILRGEPLSEEEYFKSALLGWCVELLQAFFLVSDDIMDTSITRRGQPCWYRVEGVGMIAINDAFMLEGAIYHLLKSHFRKDSYYVDLLDLFHETTFQTELGQLIDLITAPEDHIDLDRFSLRKHQLIVIYKTAYYSFYLPVALAMYMAGIQDQAAFKQAQDILIPLGEYFQVQDDYLDCYGAPEFIGKIGTDILDNKCSWNVNVALAACTPEQRRVLDETYGRKDSICEAKVKEIFLAVDIPGKYAAYEQQSYEKINGLIDGIAETPGGLKRDVFRAFLSKIYKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGC3</accession>
    <name>M5GGC3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632132.1">
        <property type="nucleotide sequence ID" value="XM_040771666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGC3"/>
    <dbReference type="GeneID" id="63686728"/>
    <dbReference type="HOGENOM" id="CLU_108109_0_0_1"/>
    <dbReference type="OrthoDB" id="3364144at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="25478" checksum="B3378135B5E45539" modified="2013-05-29" version="1">MPAFKELLSPHSEVKRVSSRLRLSFIRNFIDSLSSDPKYMNSIRAAVEEDHKYRSMYDEYKRTGKVTPLEEENDSFSLLRFRSRTGGPAGPPKPGDYNDQHIYVCTTRRTLTIHHWLFMHPTLVIDLNSIIRIRPAKDEVTEGGVEPWGVGLTGVCWARDADRALTDNEAYDRSFVCEFKAEDGEEYCAGFTVERPEKFVRVLENLIPGIRAGCSKTSRWGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGV8</accession>
    <name>M5GGV8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633057.1">
        <property type="nucleotide sequence ID" value="XM_040767715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGV8"/>
    <dbReference type="GeneID" id="63682777"/>
    <dbReference type="HOGENOM" id="CLU_1835103_0_0_1"/>
    <dbReference type="OrthoDB" id="10529263at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="140" mass="15511" checksum="BB53E8F3AA64FFD5" modified="2013-05-29" version="1">MPRLRSTLIYKEEQHASSYRTAGYQALRRTFLCFAARTSQIHLRAKKRQFTRPYKAYILALLLVFSVNDGHDNPNPPTQLPITMRLINVLLLLALAGSAPVLAQIHCEACCICDPICRNPCESEAPNCCGPEGAPGVSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMY6</accession>
    <name>M5FMY6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA mismatch repair protein MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_120061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795900">
        <property type="protein sequence ID" value="EJT96510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623408.1">
        <property type="nucleotide sequence ID" value="XM_040770930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMY6"/>
    <dbReference type="STRING" id="1858805.M5FMY6"/>
    <dbReference type="GeneID" id="63685992"/>
    <dbReference type="HOGENOM" id="CLU_004131_2_0_1"/>
    <dbReference type="OMA" id="ANYHVKK"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000109">
        <property type="entry name" value="Related to MLH1-DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="226"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="731" mass="81127" checksum="2A3FA27CFDBED85E" modified="2013-05-29" version="1">MAASAVDPKPIHRLEESLINRIAAGEIIHRPANALKELLENALDAGATQIKITAKDGGLKLLQIVDNGSGIRRADLPLLAARFCTSKLSTFSDLSKLQTYGFRGEALASISHVAHLNVVTKTRDDSCAWRASYSDGLLAPAKAGTSADPKPCAGNDGTTITVEDLFYNTPLRLRALKSPSDEYARILDVVQRYAIHNPSVSFLCKKTGSNTADVSTPSSGTVKSAIQTIYGPSVAKELLEAQAEAGTKDEFEWQAEAWFTSANYHAKKPTFLLFINHRSVESARVKRAVEAVYSGILPKGACGFIYLSLDIDPSKVDVNVHPTKREVHFLEEEAITEKVADSMQAVLAANDQSRTFQYQTVLTGHSPFKSQGKMKRSDLQKERTPAGSDEEIQSEDEVEDEENEQDLDLERPRAGPSSSLKPSRKPSQPSYKKIRNDLKTRTLDSMFPVLQSSSESQSSQPNMEIEKKEKAPAISESRCFLTSVQELRAAVKKAKHSHLAEIIVEHTYVGIASMNLCLSLVQSSTKLFLINHAALSEELFYQLGLMQFGNIGKLTLEPAPSLEELVRLAVDAEAAIKEQGLIPEKIIKSILKTIMAQRAMLAEYFSLEITSSGEVSTLPLLLPGYTPNLDRLPLFLMRLAPQVNWTSESECFSTFLRELAYFYVPGRVVQEKEDPAPEEQEEGKRKSEEWQIEHVLFPAFRKYLVPPRGLLERDVVQVAELRDLYRVFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN22</accession>
    <name>M5FN22_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623588.1">
        <property type="nucleotide sequence ID" value="XM_040769433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN22"/>
    <dbReference type="STRING" id="1858805.M5FN22"/>
    <dbReference type="GeneID" id="63684495"/>
    <dbReference type="HOGENOM" id="CLU_571099_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="53034" checksum="A1DB6D7166CC082F" modified="2013-05-29" version="1">MDEPMEVVSEMEEMKAELEQVTQELEEVQQRQKEQQQQRLQEQDSQQEKELWFLEQEDSPEQDTIMDIKVAAIMEQEGPEQTSVSENAAPPLPPPPVSATPAFLTRCLVSPIDSLSLYHTPSPVPVLPRLPCPPTPSPPPVVAIVEQGEPEQTSLSGNAAPPIPPPVSTTPAFPTQCPVLPIDSLSLYHTPSPIPILPRSPHTPTPPPPPSPPPPPPQQAFWPPPHRGSPYCPSDPSTCNDDNPNCILLPALEDWRPLISNEGGWYSYWFPMPPPPPPPCPLEFWEDPAVMNLEPLPPHLGFGKVKEPVKKPAPPKKPLNESKDLVVFDEKLVLLHSDDWHLPVGIIDLTINHGHGNWDEQMIKHMVTAITKESSQDWPGCLWVGWEAHTASVLEQQNGHDCGLWVLAQIMAVMQGVDQMSMTDAEMPQFHHWLHDNMESLPYAPVAPHAPAKEESAPLDSNKTVLELVDSDEAMDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN36</accession>
    <name>M5FN36_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_91963</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623658.1">
        <property type="nucleotide sequence ID" value="XM_040777034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN36"/>
    <dbReference type="STRING" id="1858805.M5FN36"/>
    <dbReference type="GeneID" id="63692096"/>
    <dbReference type="HOGENOM" id="CLU_068979_0_0_1"/>
    <dbReference type="OMA" id="MRDTWNA"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="52"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="30372" checksum="A22DD018777E7190" modified="2013-05-29" version="1">MGDANTPEELKFGSAYNYWIKTDAGFDLSRGSPEKITVKTTKDPIMIAPKKTALIIIDMQNYFLHEKLFDNGPGRESVPLMMETVCSCRKAGIPVVWCNMGMNEADRYTLPPSYLAMSYKRDNATFNQSIGTVSIPGQAKPIDMGGKLIKGSWNAELWGPLKAFAEEGYKLGTDVHIWKNRFSALCGHQPLELWLQENQITTTLWGGVVTDVCVWGSMLDAYYKGYDMVMVKELANTTSPDFVVKTAYRNTENWGWLTSTSSLMEGIEQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN55</accession>
    <name>M5FN55_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623753.1">
        <property type="nucleotide sequence ID" value="XM_040767647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN55"/>
    <dbReference type="STRING" id="1858805.M5FN55"/>
    <dbReference type="GeneID" id="63682709"/>
    <dbReference type="HOGENOM" id="CLU_897211_0_0_1"/>
    <dbReference type="OMA" id="CYRTMPY"/>
    <dbReference type="OrthoDB" id="2570580at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33093" checksum="05EA623FD7021A8B" modified="2013-05-29" version="1">MPPLIILGAPSRSSLISSLSPSPSSSPGTGIGSWHRLTLSPPSPSPFPQDASDSWAELPKASYVAAHSRLGEVSDLYRNAIFGGSMSMSRDEGEEEGESLEVVLHSRREETSAEASEVSHALTWEPTPNTSRTANVRDGASHTRSSLWTDSESYLPTPASSSEASIHRLPSYRVNPHSLTPLHLLPSLSRARYAPPRVNILVGVLEVSGPETVTIRKGKEAGKEVAVLKLVVGGEGSVLGVTAWRGCAKTWAQAADAGVRRGDVVLLSDLEAPRLSRTDPAPHPRAPETPQPHLLPQLHPNTMLSLHPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNG4</accession>
    <name>M5FNG4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_84966</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 12">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624298.1">
        <property type="nucleotide sequence ID" value="XM_040776710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNG4"/>
    <dbReference type="STRING" id="1858805.M5FNG4"/>
    <dbReference type="GeneID" id="63691772"/>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_1"/>
    <dbReference type="OMA" id="WRPYAEQ"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="13">
        <location>
            <begin position="25"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="259"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="273"/>
            <end position="277"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="290"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="36268" checksum="D6661BE9AFAFFD96" modified="2013-05-29" version="1">MFARSAHLLRPALARLYATPPHPSTLLYLEHASGKLTGGTLCALTAAKLLGGEITGVLMGSQTELDAVLPQARKLDGLTKILTSSSRLYVHSVPETTVPFFQKLVQDRGYTHLFSSTSSTSKSFLPRLAAQLDVQPISDVTSISVESGADIYTRPIYAGNAISTVKPTSDGLRIVTVRSTAFQQSGIGSSDVAVEDIAPAEPSEVQAEHLKTMTTESTRPELGSSDIVISGGRGLKSRANFDATLTPLADRLGAAIGASRAAVDAGYADNSLQVGQTGKIVAPSLYIAIGISGAIQHLAGMKDSKFIVAINKDPDAPIFQVADGGLEADLFDAVPELLTKLPERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPM7</accession>
    <name>M5FPM7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624071.1">
        <property type="nucleotide sequence ID" value="XM_040774103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPM7"/>
    <dbReference type="GeneID" id="63689165"/>
    <dbReference type="HOGENOM" id="CLU_2291603_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11029" checksum="486E5149C8F322F4" modified="2013-05-29" version="1">MENLSCLVSASCVHPAEPEIREKTMPGQIGVVGHQLYHDIIRHRHGESSDLDQSSPKDSAYQSRTDGNNVGRFHNNDRAHLTLSTQPPTPLGSLLAGFEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPN1</accession>
    <name>M5FPN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_26145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625573.1">
        <property type="nucleotide sequence ID" value="XM_040774277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPN1"/>
    <dbReference type="STRING" id="1858805.M5FPN1"/>
    <dbReference type="GeneID" id="63689339"/>
    <dbReference type="HOGENOM" id="CLU_124044_1_1_1"/>
    <dbReference type="OMA" id="ATYEINF"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062122">
        <property type="term" value="F:histone H3K37 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10540">
        <property type="entry name" value="SET_SpSet7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009207">
        <property type="entry name" value="SET7_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF294">
        <property type="entry name" value="POTENTIAL PROTEIN LYSINE METHYLTRANSFERASE SET6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022536">
        <property type="entry name" value="A612L_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="15217" checksum="58ED3C63B4BB3BE3" modified="2013-05-29" version="1" fragment="single">SLQILSTPDKGRGLYAIRPIAQGTVVEISPVLLFTPEEWEAHGRHTVLDHYTFIWRIPGETRPFMALALGLGSIFNHSSRPNVSFYRNIDAQTIEYTTTRDVSTGEELCISYGDSSRLWFPVVDDNALASESDEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPU1</accession>
    <name>M5FPU1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Globin-sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624211.1">
        <property type="nucleotide sequence ID" value="XM_040774016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPU1"/>
    <dbReference type="GeneID" id="63689078"/>
    <dbReference type="HOGENOM" id="CLU_063074_1_1_1"/>
    <dbReference type="OMA" id="FAKYYCN"/>
    <dbReference type="OrthoDB" id="10027058at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="1">
        <location>
            <begin position="25"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="25829" checksum="7440457AB65FF058" modified="2013-05-29" version="1">MSDARAHGCPVMKHVDHDSLYTNLEARMDYLLSFIEFGKEDIKGLKDVAPILGPLIPTILDAVYTKLFRYDVTKVLLLPRKMGYQQDELESGLDSFGHDSEQTKIRKEFLKGWLVKLLTGDYNSMSQWDYMDKVGIMHTGKAGFKHREKKAPLHVEYIHMAGLLGWLETMFTTTLLRIPDAKVSPKDKLRMITALNKIFWIQNDLFARHYIGQSDLFARHYMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQF1</accession>
    <name>M5FQF1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pkinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_118377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626008.1">
        <property type="nucleotide sequence ID" value="XM_040770570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQF1"/>
    <dbReference type="STRING" id="1858805.M5FQF1"/>
    <dbReference type="GeneID" id="63685632"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="FHERYWG"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="59815" checksum="28BB751FABBB888A" modified="2013-05-29" version="1">MPPRIHSFSDLRESLLPQPASFQKKKSYHIHSLLGRGTFGKVLRATWVAHDPHLDVALKVINKKKVKGNEELVFQEMKVLEGLVHPNIVKFYEWFESREKYYLSFELAQGGELFERIVQRGKFTEDDAVKLISTICDAVRYLHAHDIVHRDLKCVSHSPSRWGPQVTSVSYCNRPENILYRTDAPDSDIVIVDFGIATHLETPTTELHTLAGSYGYVAPEVLTDKGHGKPVDVWSIGVITYVLLCGYAPFQNPDEEEMIEKTVHADVRFHEQYWKNVSQEAKDFIIALLTVDPHKRPTIEQVLQLAWIRHHIPGSQDHDLAGLREFNAKQKWKQAFNAVKAQHRLASFSKESQRHLLSTYTGSSGGWASSSTSLANSYVDSDDEGSGTHTPGETAHARMNLSKLREAHVNNPNAAPVLGPGEQVGGPALPRLSVTHHDAPQPAAPTNGHSHSHMHEKNDEGATTPIAHSGPSRHLSRPVIDPGHPTADEADIPEDDEEEEDDGMANMPGSFHRPAVSRGPSGDEGILSRAMEALLGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQG8</accession>
    <name>M5FQG8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626033.1">
        <property type="nucleotide sequence ID" value="XM_040771305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQG8"/>
    <dbReference type="STRING" id="1858805.M5FQG8"/>
    <dbReference type="GeneID" id="63686367"/>
    <dbReference type="HOGENOM" id="CLU_046006_6_1_1"/>
    <dbReference type="OrthoDB" id="10249419at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006:SF2">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="143" mass="15671" checksum="3D6985C645BC25D9" modified="2013-05-29" version="1">MADFYAPNNNRAPFSHIAIDVTSLAESVPFYEKTLGVFGWTKTFERPGAAAAFGPGYFQLVLFEKADGVRGRTGRGGTHIAFEAPSKQAVHDWYEEAVKLGATANGEPGVRGHLSPNYYAAHVLDPEGYRLEAVYHLKPEEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP7</accession>
    <name>M5FQP7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_17444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626148.1">
        <property type="nucleotide sequence ID" value="XM_040771285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQP7"/>
    <dbReference type="STRING" id="1858805.M5FQP7"/>
    <dbReference type="GeneID" id="63686347"/>
    <dbReference type="HOGENOM" id="CLU_060356_3_1_1"/>
    <dbReference type="OMA" id="PLYPHEG"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="13"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="270" mass="30407" checksum="A18BF149950C9908" modified="2013-05-29" version="1">MPVVKSTRVQLFEAWITVDHDRLPEYAPEYDPDTNTWTCWVSSEVDKHFVVHWRNFGRPFTSGAFVYVDGEFADGKLLMRHNPSQTTFVNGKRTTSATVARFYFQPIVLTDEENPFVLEDNTTVNALGEIKLVIQKGKNTGAISYEHGAVREAKAVNERTKKAGGHRVQYADEVADMDAIGASFEPDSTVMPLTFIFKYRSKERGEAVGGVDLNARSLRSRHAMKEESNVKEELGLKEEPGETSLDASASTSRPRTRSRTRLQNEEEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRJ9</accession>
    <name>M5FRJ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carboxypeptidase S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_83450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625221.1">
        <property type="nucleotide sequence ID" value="XM_040776625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRJ9"/>
    <dbReference type="STRING" id="1858805.M5FRJ9"/>
    <dbReference type="GeneID" id="63691687"/>
    <dbReference type="HOGENOM" id="CLU_021802_11_0_1"/>
    <dbReference type="OMA" id="ETDFVWG"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05674">
        <property type="entry name" value="M20_yscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000027">
        <property type="entry name" value="N-fatty-acyl-amino acid synthase/hydrolase PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017141">
        <property type="entry name" value="Pept_M20_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047177">
        <property type="entry name" value="Pept_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962:SF1">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037217">
        <property type="entry name" value="Carboxypeptidase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="9">
        <location>
            <begin position="312"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="613" mass="67898" checksum="95B93D04F45963D5" modified="2013-05-29" version="1">MDKLDTETHLPLTGRPSYGPRRRSRRFGLEVYVDVRAIPLLYLLYVAWAFLLSGKVFDTFDRWAEVIESSKWYLDIFHPVELHNYGRCVQPEGLVPSNRALVDTIYADFWNEVFQNKSAELLGAAVQIETESYDDLGEVDKDPRWEEKYAPLHQWLEGAFPHVYKALQVETVNTWGLVYTWQGSDPSIKPILLAAHQDTVPVDRKTMSEWVHPPFSGYYDGDYIWGRGTCDDKEQLVGALIALELLAKHEFKPTRTIILASGFDEEISGMHGARTIGELLLGRYGEEGIAFVIDEGAGYGDLLGRTVAVPAIGERGHVDVKVQVNYKGGHSSVPPGNTGIDILSDMVHTLNRNPPKAFLSQKNPFYDTLQCLAAYSPDLPDSVRKDIIRSSSSSSALKRVTNWVLGLPSGPLSPLGGTLIRTTQASTVIQGGVKVNALPEQSYVLINHRIVPGSSVAQAQDRISSLLTPTAEAYNLSLSAFGKSVIPSTGKEGSVFIGEAFSPGLEPAPITPQAAEWRLFGGTIRAEWAKRGPSLKSGSDEEIIVAPGVMNVNTDTRHYWKLTKNIFRYAHLDPKGMYNGLHTVNEAITLDNFLGHVRFMALLILNSDETRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR8</accession>
    <name>M5FRR8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase EFM6</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Elongation factor methyltransferase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EFM6</name>
        <name evidence="2" type="ORF">DACRYDRAFT_25061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRR8"/>
    <dbReference type="STRING" id="1858805.M5FRR8"/>
    <dbReference type="HOGENOM" id="CLU_055721_2_0_1"/>
    <dbReference type="OMA" id="WEGYIFS"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03198">
        <property type="entry name" value="Methyltr_EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033684">
        <property type="entry name" value="EFM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="109"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="261" mass="29238" checksum="8C2D6C78E5D93BDA" modified="2013-05-29" version="1">MAEILREEERLDELDPLRHLRDNDADAAGNTDEGISDGFIVPAQRPSIINQLQILSFPVLVPELRLSVDASPGCGGIAWPAGEVLSRYICLRETREPGWMKTRTVLELGAGTGLVGLVAAKLGAKHVVITDQTPLLPLIERNIVLNNVQNACIAAEFNWGEPLSEAIRTGAFDLILAADCVYLEPAFPLLVQSLCDLTNESPRAELLFCYKKRRKADKRFFVLLKKHFEWEEVDDDPERPVYSRDTISLLRFRRRGVKASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS77</accession>
    <name>M5FS77_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627093.1">
        <property type="nucleotide sequence ID" value="XM_040773143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS77"/>
    <dbReference type="GeneID" id="63688205"/>
    <dbReference type="HOGENOM" id="CLU_1042145_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="147"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29638" checksum="088544A1450AE61D" modified="2013-05-29" version="1">MEPFPVNTVAITVLSAEEVQILQEMQQYRDGLRRRFQSAPLACHRCNRLKEQGDLSTEQEDCPNCGRDDLNRIGAPAPEPASQRTQASFHRVARIPQHASSSPESVLIAGGDYSDIDVSDASGPSGWSWSTPTWESPGSSFKPRASACLSCKRLKIKCIRRSRGTRCEPCLANHERCFVQARSPREKSQRYVDDTPAEDTDEDITMDELGAYLEPEDCPTPVEQCQRDAIAEEPTTHQRAIPPDLQKQPNHPPGAVSYQAPHGDRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSF2</accession>
    <name>M5FSF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_44125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627248.1">
        <property type="nucleotide sequence ID" value="XM_040774556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSF2"/>
    <dbReference type="STRING" id="1858805.M5FSF2"/>
    <dbReference type="GeneID" id="63689618"/>
    <dbReference type="HOGENOM" id="CLU_2339104_0_0_1"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="10706" checksum="CC80D98237445DB2" modified="2013-05-29" version="1" fragment="single">DTCILPLSPSLVDRLKPHLQNVEPIANIITEGDELAAWKSLLVIFVERGRAWKHQASCDPICTCGNGLALGSFSKSLWKDLAPHVTRAAISPLFAVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSI3</accession>
    <name>M5FSI3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_18224</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625042.1">
        <property type="nucleotide sequence ID" value="XM_040771343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSI3"/>
    <dbReference type="STRING" id="1858805.M5FSI3"/>
    <dbReference type="GeneID" id="63686405"/>
    <dbReference type="HOGENOM" id="CLU_796996_0_0_1"/>
    <dbReference type="OrthoDB" id="343092at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21292">
        <property type="entry name" value="EME1-MUS81_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT98144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="348" mass="39585" checksum="AABFA98428CCCA9B" modified="2013-05-29" version="1">MYSVSRSLPKSDITKGAAKTSKALEKKAEAERKKAERLRLKAEKDAAKAAEKAHAKAVKTVNKLISSKKDTLPDMFVETIVDKSGKPGARDWPIRVVDELDPPNSICWTRRVKSRYDEGTRQFVPLDEPLSVIENARLLYLQKEHLQNGLKSGRLEQTVQRLRDELGPKALLFAMIDGGGRSKETERQLTMRMMKYQLNVIRVDGYQDAATWLYDMTADLGYKPYRLLEKSHLPNIGDTNIDAGANSRDTWYKMLLQVPRMTESAAQGIMKEYPTFHSLMSTYQLAGWQGERLLENILITKRKDGMDRQRQRLGGRLSNRVWRSLTSEDPDEHLAQFGQGAGIDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSM5</accession>
    <name>M5FSM5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625097.1">
        <property type="nucleotide sequence ID" value="XM_040770692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSM5"/>
    <dbReference type="GeneID" id="63685754"/>
    <dbReference type="HOGENOM" id="CLU_091090_0_0_1"/>
    <dbReference type="OMA" id="CNILMHT"/>
    <dbReference type="OrthoDB" id="5399848at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="23488" checksum="6B6588A608188223" modified="2013-05-29" version="1">MLLCSNRTPVTGSPSTCTLDVVVIPLASWILMASLPLTVIVCSKRRQALPLSRTRLQKKIWILYLVLIVADIAMTVLEIARLAVAQLGVGLLPFNTVGLIIAVVLVGIRGSTFMPLFFFWLLLVIFQAIKVHQLMYLPSKTPDQYPGSDQLLDNAIMLGLESSFVLLDTYDSIVHWKHRLRTHDALVMHPALSEGNLPLQPTSEVTDTTTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSN7</accession>
    <name>M5FSN7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627388.1">
        <property type="nucleotide sequence ID" value="XM_040768678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSN7"/>
    <dbReference type="STRING" id="1858805.M5FSN7"/>
    <dbReference type="GeneID" id="63683740"/>
    <dbReference type="HOGENOM" id="CLU_021768_2_1_1"/>
    <dbReference type="OMA" id="HEALVEW"/>
    <dbReference type="OrthoDB" id="4177236at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF39">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="262" mass="30651" checksum="E0B5ED08A3513A2D" modified="2013-05-29" version="1">MSYWVQWLWDTLTGSKQPNVKFCEPSAPTITLDDIDHFYKSGQWEKARLGCLEEDGLGVFGHNVSRMSESVAVKCMDWRDRQFEPYTMRLISTQTSIPTPRVHECLIRDRTMFFVMDYIDGEDFYTLWPNLSLFGKCRIMWTIRRYIRELRTWKPPVPDIPGPVDATEKPVRCIGTEFGEGPAGPFNSYADLYDWFEHKRALAVDMAKNWFHYELDEKKLPHFDSSMPLVFTHGDISMHNIRISRDGTVWLLDWGSSGMYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT03</accession>
    <name>M5FT03_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625367.1">
        <property type="nucleotide sequence ID" value="XM_040773707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT03"/>
    <dbReference type="GeneID" id="63688769"/>
    <dbReference type="HOGENOM" id="CLU_012970_2_2_1"/>
    <dbReference type="OMA" id="QWHNPSM"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="602" mass="65555" checksum="975CCDB4C7D3902A" modified="2013-05-29" version="1">MEQPRASIEATDQEAYDRKIASETNSIEEFTQEGVIKAEKARAVWGLRGSIALWIGVGLSSFMYTLDNGTNYQWGSYATTQFNNYPAYAAIQCASSILLALGKPLFAKIMDSLGRAEAYCFSLFFYLLGYIIAAASPDITALGAGLVIWVIGFSGLQIANQIIIADFTTLRWRGLVQSLTSAWYFILFWANGKITQQLVAPGGPGWRWGYGIYALCYIPALGPIILTLLWGQYRAKKLGLVEQPRAAAQRRSRLSGAWKWIQESDLIGLFWLGASITLIFLPLVLAGGSYATLSWQSPTIPAMMVIGGAVALPIFIYWELKRALFPIIPFRLLKNRTVLAACLISFFDFISFYLTYAQLYGFVAATTNWSLSDITYYTNCQSLCLTFFALLWGAVAIVLKFRYKWTLTAALCVRLIGIGLMFYAREHNSTAALVMTQVIQGAGGGVAAIASQVGSQGAVPHQDVAVATAVVLLSAELGNVVGSAAAGAIWRSALPEQLTNALADVGFTNTTYITMQVGNPLLAQTSFPDLSDPIREAIHSGYSSTMRLMLIPAIVLSVIPIIASVFMRDFHLVDLQNVVEAKDLQGNKVAGGDLETIESGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT33</accession>
    <name>M5FT33_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627608.1">
        <property type="nucleotide sequence ID" value="XM_040768733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT33"/>
    <dbReference type="GeneID" id="63683795"/>
    <dbReference type="HOGENOM" id="CLU_1643649_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067151" evidence="1">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="161" mass="18075" checksum="943682A4E3E98690" modified="2013-05-29" version="1">MFFAKAVLLAWTIAIQVTFAYPVRTFDSRDENLLEAREELVSLQTRSPESIDVLGDILFLRSTDDAEWEDELEMRHNPLIAPLKGTVGRITSNVKAVTHKIAHPVETWTKIRNPPLDRVASTRSLYGDKPTLVDKIKASVHPTIKAVLNHVTGRKDSTDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTD1</accession>
    <name>M5FTD1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627783.1">
        <property type="nucleotide sequence ID" value="XM_040767461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTD1"/>
    <dbReference type="GeneID" id="63682523"/>
    <dbReference type="HOGENOM" id="CLU_026023_0_0_1"/>
    <dbReference type="OMA" id="KEACASN"/>
    <dbReference type="OrthoDB" id="2959034at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="406" mass="44746" checksum="31CF7FC64F4E2D9A" modified="2013-05-29" version="1">MVITKEPLTPDGSSLDTPPSYDSLSTSSSRPTGDQKRPIPPWPPNSQSAQAGSSHYSLPSPPSRDGPASAKWSPLTPEYWRRRREEDEIRRTVRDLLKDVIHNLSDPSSLDVLHSSYVACASHGISFPSLSQELIESHPPLYWAVLTLSPLARALPGGQLASSPPPDGWSALDLLTAFPLKGETQREAIAACVLGDDNALFQYLRASEGFAPQGLAESIISRPGEEGRARAVDFVHVEHVPDGQAGHFKIRFKCRDWLRRMRMHKKIVMRWIARGRAWQLVFGMADGSQPVSQGNWYCAIALVRGTGSNNAPLTAQIQIGNTDPLPPTDRLTPGTFPPPTSASDSPERKTVTLKLQHRDLRDDYEYHYCVKLSDFPGAASLEYEDSPFIEPDGSVCMQGDFVLEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTI4</accession>
    <name>M5FTI4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RmlC-like cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_110588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625582.1">
        <property type="nucleotide sequence ID" value="XM_040769084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTI4"/>
    <dbReference type="STRING" id="1858805.M5FTI4"/>
    <dbReference type="GeneID" id="63684146"/>
    <dbReference type="HOGENOM" id="CLU_064194_3_1_1"/>
    <dbReference type="OMA" id="THHHREF"/>
    <dbReference type="OrthoDB" id="10261807at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="229" mass="25117" checksum="2CE26D93835AE993" modified="2013-05-29" version="1" fragment="single">GFGSLRVLNEDRVLPGTGFGTHPHSEFEIFSYVVSGELEHRDSMRNVEVLKRGDVQLTSAGTGIRHSEKTFGASPVHFLQIWAKPRVSRLVPKYFTRHFSDEEKTDKWVKVVAPVEAEGVLDKREGDGPAPVQSGVTMYATLLSEGNSLAHRLPLDGQGKTRKVYVHVVQTSGYNDGSSSGARVKLSGEGKELELREGDGAYIAGLPERELILENVGEGRAEIVLFDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTQ5</accession>
    <name>M5FTQ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sucraseferredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_55826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626391.1">
        <property type="nucleotide sequence ID" value="XM_040775346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTQ5"/>
    <dbReference type="STRING" id="1858805.M5FTQ5"/>
    <dbReference type="GeneID" id="63690408"/>
    <dbReference type="HOGENOM" id="CLU_1763161_0_0_1"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF14">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16235" checksum="7CE60D82D6647CC4" modified="2013-05-29" version="1" fragment="single">MHHATKQVYATFYRLGHLPTPILLQPGDLPTLAQLQLSPPIGEEETHIYVCTHGARDCRCGTTGVAVFRALKAEAGRLGRGGSKRVRVREISHVGGHKWAANVLVYPPGDWYGLIRPGEAGELLARVGEGVGVWAERWRGRMGFGEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU24</accession>
    <name>M5FU24_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-hydroxyacid dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_119923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623604.1">
        <property type="nucleotide sequence ID" value="XM_040770893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU24"/>
    <dbReference type="STRING" id="1858805.M5FU24"/>
    <dbReference type="GeneID" id="63685955"/>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OMA" id="HMGTETC"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000203">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase (SerA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF257">
        <property type="entry name" value="GLYOXYLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="69"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="122"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35883" checksum="2D802BE20441A5EE" modified="2013-05-29" version="1">MSRPKILVSGHIAWANKEVYELLEPFGDIVWLDGVPTRNDFKNVFLPQHPNIVGIYRHNSSSDRIGVYDKELVDMLPSSVKFIAHNGAGYDQIDVAACRARGIQVSNTPGAVDTATATTALYLLISCFRQFAKAELNARARNWKNGLLPAHDPDGKILGIVGYGGIGGVLAQRCRDSFGMKVIYYNPRPRTDAPAWAEYRPTLVQLLKEADVVSLHCPLREETRGLIGATEFEQMKKGAILINTARGAVVDEKAMIGALKSGHLYAAGLDVYPSEPHITEELYSFPNVTLLPHMGTETEESQKSMEVAAMKCLVKAFETGEIGNRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUH7</accession>
    <name>M5FUH7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_116568</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628293.1">
        <property type="nucleotide sequence ID" value="XM_040770225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUH7"/>
    <dbReference type="STRING" id="1858805.M5FUH7"/>
    <dbReference type="GeneID" id="63685287"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OMA" id="HAFKGAY"/>
    <dbReference type="OrthoDB" id="9997102at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="33189" checksum="1E170BEB7E47AD6E" modified="2013-05-29" version="1">MSKKIVVVTGATGKQGGSVVSALLRHGGYTVRGLMRNLHSALSRELTAQGAEMVQASLMEKDSLIHAFKGAYAVFGVTVPAEESDFEQGKNMVDACLANKVDLFVWSSLPSSSELSNGKYPMRFWDDKYAVDKYIKAVGQPSVIFMPGSFTENLISFGQLKPVASDTWEIQYPVATADYVQPFLYVEKDLGEAVTALIDHWDDADWKERLTKDVIQMSSYNITGGEMAGIIARITGRDVSYVLSNNVPDFYKTMWEFCVEYWPTPEAIPSKVLLDLGIKFHTFEDYVREKLVPFMNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV02</accession>
    <name>M5FV02_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_117671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626981.1">
        <property type="nucleotide sequence ID" value="XM_040770431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV02"/>
    <dbReference type="STRING" id="1858805.M5FV02"/>
    <dbReference type="GeneID" id="63685493"/>
    <dbReference type="HOGENOM" id="CLU_004025_1_0_1"/>
    <dbReference type="OMA" id="HMEVRCR"/>
    <dbReference type="OrthoDB" id="272977at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="7">
        <location>
            <begin position="180"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="8">
        <location>
            <begin position="480"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1217"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="258"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1225"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1259" mass="140972" checksum="E67C9EFC466B7EFD" modified="2013-05-29" version="1">MSRQGPFPTQRSRQPPDQSYNYGGGGSLSTPPLNVSRNVRDVQQSGRGASPLPASSSAPMRPARSNLRERLNSSDSVPSANQWRPAHQPSDSYASARFAPSDEEQGLIYDEPQPQPEAETPKALGAVIAAFQNAGETRRKMTNGSAGSEVNGRSKRREGIDRSRTQDRERRTNGKGPTNELDAMLDKIKDKWGVLADEDFNPVEVALSLLDNSSVGRDIDSFRRTKLALERALKATVDKHYQSFAASLPHHAALLTSLSSTQDQIQDAKTRLTEVREALGSKRADLVQLWSRNQALDEMMKLLDEIDRLKSIPDQLESLMTEKRILQAAVLLVKNLKTINKPDMLEVGAVADLRSYLSSQETALRDILIEELHNHLYLKSFWCESRWSAYTPGQESLPIQEAPQTSSQPQAIPNAQTPSTPVRPPTKLARFLTDLAVRPTIDPLLDIIPSPLYSSPLMTAFTSSGNFPDDVQSGPAPSKNPESDSFMYMETVLESLAVLGQLGYSLDVVAQRLPAEIHLLIETTIDEVTERQESQRRQSTFTPSSRLSLSNVSSPLSNVVIKVTNLGRLRSPELEGMEKETEREVLRDLFWTLYSKLDAVLQGLRVVFEVTGRISSRREFKDSSGARPGTLFPLGELYQPLLSEVQMLLRDQLTDEDRAASVVNPIASISEALQGRTSRDRTKHSFRFTESDVKLSVRVLKKHEEELNRVLKDNVPGLVQSNADSVTALSRAAKDDRFAATEKHRLLIRPSAFHVSVLFHPTQAFLHRIGEILPSSVYDSFKDDNALLDDFVLHVYLPQLEDKVSNLVHSAISGPDAFEEDPTSLRISPKPLVKACTQLMAVINSLCAMLQSTNFHRENYSRLILSVVIHFYQRFNMRFQALVARNSIGLVPDVVPDAMLHISARWAQKPEVSACLSELYATPDTDTIKKQTVCQQETRIELSFLNNEEITRDHLIPLRNLAELCRLHYSLTWFIHQLSTLRVLAEDPISPQSAADPLSKFFSPAKPTFKPKQGLSGQHSIENENLSLPLTKAMALRFDALLKTYDLLAEVILFSTRIDIRCRTIHYLNLAIRTNDFLIDQAPLEPDVQVVELNADMGKIDDFAASTLPERERRFLFEGLGSLMDQLLVSGGRYINLMNSHGLERVLRNLLALEQNLKTMTGDEARDADLSRARRYWAMFAGGPKEMLERAKVGPPQFSFDEYRAMLTLQCGVEQLKENPGSAGQPEQDSARSSMTENADRRAYNEFLIDLHALAIEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV95</accession>
    <name>M5FV95_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_52384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628593.1">
        <property type="nucleotide sequence ID" value="XM_040775102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV95"/>
    <dbReference type="STRING" id="1858805.M5FV95"/>
    <dbReference type="GeneID" id="63690164"/>
    <dbReference type="HOGENOM" id="CLU_003921_8_2_1"/>
    <dbReference type="OrthoDB" id="5596707at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="94" mass="10738" checksum="6682A70AB5B8FDA5" modified="2013-05-29" version="1">MESVNGLVNQLLGHVPNLCIGISSLNFYVQAFVLPNPPFHLLLSCPFHVLASCMTQDYMDRKQKVQITCPNPHQTINLWTQLHHMGRKHAIQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVU3</accession>
    <name>M5FVU3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626617.1">
        <property type="nucleotide sequence ID" value="XM_040773372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVU3"/>
    <dbReference type="GeneID" id="63688434"/>
    <dbReference type="HOGENOM" id="CLU_2497857_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9454" checksum="3FAF93AFBE62F777" modified="2013-05-29" version="1">MEAITRKTFFPTGDWLPRTVDAHLTFKPCEPQECNKCATLREFDGLISLDSFRCGRSGVSSPVGCGIEPTHGPVLQCFCARCTSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWJ0</accession>
    <name>M5FWJ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626952.1">
        <property type="nucleotide sequence ID" value="XM_040773291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWJ0"/>
    <dbReference type="STRING" id="1858805.M5FWJ0"/>
    <dbReference type="GeneID" id="63688353"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_4_1"/>
    <dbReference type="OMA" id="KSAYHIP"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22967" checksum="BECC6C7B6E674F5C" modified="2013-05-29" version="1">MGIVTPPSKVLVTGANGFVGVWVVRLLLEQGYYVRGTVRSEQKATYLKVRFAKYDDKLEIVVIPDMLVATAFDESVKGVQGILHMAAVVSLGGTYESEFSYNGLRHSLTALSAIVKPSIVMTENILNSTLKYGTDVRRLTITSSAVALLQPQEPGYTYTDKDWNEYAIQEMKEKGDKSAYHIPYFAAKTMAERAAWEFLRFRAPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWJ9</accession>
    <name>M5FWJ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629213.1">
        <property type="nucleotide sequence ID" value="XM_040768434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWJ9"/>
    <dbReference type="GeneID" id="63683496"/>
    <dbReference type="HOGENOM" id="CLU_548625_0_0_1"/>
    <dbReference type="OrthoDB" id="2576334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="54169" checksum="9FA5F7D969065003" modified="2013-05-29" version="1">MALPQIGLNAIGSNLTLGSQSPVFTYLPARDGSVNNGWNASYTGTTHAEAYGGGVGVGTAYRETQMDGASVGLSYNGTSVYFCLGLSSYPASFQLTVDGITGAYTIQQSSDPACDGYEGADSVVLVNNLQDGAHEVSLSVSVDQPGYVRFYGAVVTLIGGSTEQVLKRTNISWADKSWIYEPTGVWGNRPDYDLFNNSLAIGDLEGSSRWARTYDPTSIAEISITDTSVFYLLGPIGPKFANYTVSFSGASQTFIPTNYFAAYQQVLYFAGWLDPTLAYTLTLQNWDEQNPAQTSAMYLAIDALVLMKPVAASEYRHPRVRNQVPHMCSRGPTYPDSHIYFIPLHPHIASTRNSRWSSGRPGTPHRASSTPDALTSEAMEDATRSRRRRSTFATRPFSILPNPNQSLQVLEAYITQRHIYLIVSTPAPEAGSDHLHAEPRPPNIDRFCHLYLAPVHSDREGSSFLFGAEPGHTSNEDHITNDVEDTNYAAGSKQLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX01</accession>
    <name>M5FX01_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_115582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629415.1">
        <property type="nucleotide sequence ID" value="XM_040770035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX01"/>
    <dbReference type="STRING" id="1858805.M5FX01"/>
    <dbReference type="GeneID" id="63685097"/>
    <dbReference type="HOGENOM" id="CLU_711773_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF1">
        <property type="entry name" value="ACTIVATOR OF STRESS GENES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="388" mass="41222" checksum="BF3AEEBD04316CED" modified="2013-05-29" version="1">MSTSTRGVGTGGKATKPTVDEQSEQESGSEQGTTKEGEKEIVEAASVEENLQLPSVTYGQQAEEARRAYAQYYAQFGPNSQHLGTGPPHPPWPYPPPGAYYPPAYIPVAPDGTPLYPSFYAPFPPGARPLPGGPMIVAPSGVIPIAPNAQAPPEQPRVTSGLSVPQRPRTTVTDKIFIACSYCRHRKLRCSGDTPKCTVCVRYDQICNYDDHRRTRGPGRKSLVALGIDVPPSKKQPKKKAKEAATTSITSSSALLPPPPPTSNCQAVPTFPPPPFPASFSAGSPPDTGVSPQALEGSAITAAAILNALPTLQAALARQNIPPYPSLFRSVSGPPQSPTPSPHHSPQDHAESSVEDVEPKTTSPKAKKRRAKDESSSSPKKRKRGHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX40</accession>
    <name>M5FX40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627187.1">
        <property type="nucleotide sequence ID" value="XM_040768793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX40"/>
    <dbReference type="GeneID" id="63683855"/>
    <dbReference type="HOGENOM" id="CLU_2867609_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="6914" checksum="E773BFB0131F7D1D" modified="2013-05-29" version="1">MPDARDIILPPLSAGAAHMMVFGSPENFSAIVQIVAAERLEGKEPADWILELSDGEWAFRTTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXC1</accession>
    <name>M5FXC1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627317.1">
        <property type="nucleotide sequence ID" value="XM_040768822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXC1"/>
    <dbReference type="GeneID" id="63683884"/>
    <dbReference type="HOGENOM" id="CLU_138047_0_0_1"/>
    <dbReference type="OrthoDB" id="4185642at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12316" checksum="FD06FCAC922C50DE" modified="2013-05-29" version="1">MLDLLIERQYPPPNDEDEEVIGEDRFCTERAVYEAFRHAYETNPESLPRELVAGYAILVTEFVDGPSLAGMPTSKELKCAALRAMIDVLAAGVVHLTIKSEPLSSAPDPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXD1</accession>
    <name>M5FXD1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Ubiquitin-protein ligase molybdopterin-converting factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_80606</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HesA/MoeB/ThiF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628016.1">
        <property type="nucleotide sequence ID" value="XM_040776457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXD1"/>
    <dbReference type="STRING" id="1858805.M5FXD1"/>
    <dbReference type="GeneID" id="63691519"/>
    <dbReference type="HOGENOM" id="CLU_013325_9_3_1"/>
    <dbReference type="OMA" id="GSWVVTM"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000125">
        <property type="entry name" value="tRNA threonylcarbamoyladenosine dehydratase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="14">
        <location>
            <begin position="95"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU01119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="477" mass="53297" checksum="EBC8915A7D232805" modified="2013-05-29" version="1">MPWHLSLSSPSLPSPSAHPRVTLLITAIASSALTFGAFQSYTLLSRARRAAQLKQSVQEALQDEPLTLADERRRRRLQEDTNVSYDEELIREQLARNYAFLGEEGMEKVRKARVVVVGCGGVGSWAAVMLVRSGVGHIRLIDFDQITLSSLNRHATATLADVGTPKAASMTKFLKSVAPWCEVDARISLWRDTEEGARLLEGADWVVDAIDNISTKVDLLAYCSKHNIRVFSSMGAGLKRDPTRMHITDISLTQEDPLARSVRRRLKAKGVLSGIPVVYSTEVESDVKLLPLPEEEFEKGKVAELGPFDDFRVRILPVLGPLPSIFGLNAATYIVLDLAGKPLTNPLAAKGRRKLYDKMARDLRAREARLYTNGMESSKLPISEHEIEYLLEDLSRSRSSLPPHPLLARPTLVRWDPSLPLTVDNVAVFSSEEANRHEREVLKGGKSGEEVWGKEMEEIMSRRGEEAREWRRGWMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXP1</accession>
    <name>M5FXP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629690.1">
        <property type="nucleotide sequence ID" value="XM_040777626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXP1"/>
    <dbReference type="STRING" id="1858805.M5FXP1"/>
    <dbReference type="GeneID" id="63692688"/>
    <dbReference type="HOGENOM" id="CLU_006580_0_1_1"/>
    <dbReference type="OrthoDB" id="691197at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="184"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="707" mass="77810" checksum="322E4C07F60A501B" modified="2013-05-29" version="1">MSGPKVPFQETWQRWSTRATSQLAPIKEKLRNTATQVAGIAETMQELEDDSQQLALKVTWVTQIILDRIAPDGPGDERAKEVVSALAAKVSEISAFLRSGTKKGDITGKRARKISKYHKTLDALRLQCVEIHTDVSNDMAGRSLGQQGPFLIDIPPTPEAFYSRDEVVESIVQLLLQDKLCRVPILGPGGIGKTSVAAAAMNDEQVKERYREHIFFLSCEGIDSEEGLVNALAVFFRVQRDSNTRTALIAHLSSLGRALLTLDNFETTAQSDRQHIRELLGRIGRVPSFSLIITMRGTQPAQGLTWDDVPPLQNSHFSVATGYGDCGPLLKTSIATLRGSRSTGGSDSLSNSEDTDSVYRIGDEERDIAECLKTLGNVLIKQFRYEEAAAMVTEARAVFEAIPYRLGVAQCMRSHGEILRVQSRYDEVAAPFTEARAAFEVIPNRLGAAQCVRDLGDLLRLQSRYDEAAALLTEARAAFEAIPNRLGAAQCAHLLAHILNMQSQHEEAAVLATEARAAFEAIPNRLGAAECVRDLGDILRMQSRHDEAASLLTEARAAFAALPHRLGAAHCTQLLGESMRMQSQYEEATSLLTEARAVFQAVPQHFSAAVCILGLGNILVDQSQCTEALSMLREAEKIFEDSGTKWELADCKQSLAYLFVKQGRISMARHMLDEAREIFEAKYWGSFQGGRVHCGTVGVRQRRRDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXQ2</accession>
    <name>M5FXQ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627462.1">
        <property type="nucleotide sequence ID" value="XM_040768694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXQ2"/>
    <dbReference type="GeneID" id="63683756"/>
    <dbReference type="HOGENOM" id="CLU_994049_0_0_1"/>
    <dbReference type="OrthoDB" id="10658166at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="280" mass="31545" checksum="DEE3EAE8FD807338" modified="2013-05-29" version="1">MFHFFPRSSSSSASSSSSSGPGNMESKSRFRLFRRRSQDDKQDPVSEDFDELSLPDPYPSFSSAPQFIDRPEIVDRPEDVQEALARLRDTPYSTSTHSLRHYPRVMLAPSALSPPLRTSFTSSSGSSWPSSSASSFTPRQGWRSYDFEGEDEEELKPPRRHWSDPGHSSHQRKRSSPSASRMSYPALSTHPSHPSRPTRVSSLSPRSRALPKPRLPAASSISSTSSTSSVFVQHQEPLDFLLPEERFALRRRHDDATLGISPWEPPVRHGPGRRGNYYFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXT3</accession>
    <name>M5FXT3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mfs1.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_22497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628211.1">
        <property type="nucleotide sequence ID" value="XM_040772831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXT3"/>
    <dbReference type="GeneID" id="63687893"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OMA" id="TEMDETW"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="58"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="488" mass="51814" checksum="6C81298D523AAF8B" modified="2013-05-29" version="1">MSAVTHPDYGSTSTSALEPKTAVERTTVVTTVPDADADVDEMPPPPADFKTDLGFWIIILSLALILWLAALDLSIVSTALPTIISDLPGSTSFVWVGSAFTLASTAILPLSGNLAQLFGRQATVQGFIALFAVGSAVTGAAKNMQTMITGRTIQGLGAGGMLALVDIIIADLVPLRQRGLYEALLSGIWAVASAAGPPLGGVLAQVGQWRWIFFANLPLCGIAAAMVWRFLKLKRPPGSWRRKLRRVNYIGNAIVMGAATSVILALTQGGVDHPWSSYQILVPLIIGLLGMVIFLVYEAFFCVGEPMVPLSMLSNRTVLSGYAGTLVHGLVSILLLHYLPVFFQSAMLATPLRSSVQSLPTALTIASFAIRAGVSVAVTSHYVSQNVAAWIISIVGFALLSTFHKDSSTAQWVGYQVLVSSGMGVLWISTEFPVLAPLPTSKNAHALAFFAFLHTAANTFGVTIGAAVLQNELRRLLPPTFSESLPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY65</accession>
    <name>M5FY65_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TauD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_110945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625399.1">
        <property type="nucleotide sequence ID" value="XM_040769150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY65"/>
    <dbReference type="STRING" id="1858805.M5FY65"/>
    <dbReference type="GeneID" id="63684212"/>
    <dbReference type="HOGENOM" id="CLU_036005_0_1_1"/>
    <dbReference type="OMA" id="QDRDPNQ"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF31">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="61"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="378" mass="43017" checksum="D479217B4E205867" modified="2013-05-29" version="1">MSAFVKMPHAPTFEAETYEYKHYLPNYPVRDLEPHVELKMADRGFNADPEMKAFLGAATKVTNLTACIGTEFEGIDLRQLSDKQKDEMALFAAKRGVLVFRKQEISIEGMLDLARYWGPLHVHSTTGHPAKGPSDFALDAVVLVWNDGTKDVDRINHDRRLAWHSDQSFEINTPGLTSLKVITNPPEGGDTIWSNSAALLSSFSPELQEYLSKLSALHSSDRQKKGALDQGIYIRRPQTDCIHPVVRVHPVTGMKALFVNPSYTRRIVGVPKAESDMILNFIYGQISLCEEFKVRVKWEKDSIVVWDNRVLWHTATYDIYPYKRHALRATPVGERPMSVKQYIKQYGKEPTSWDEERLKKLGENPQAFLATYKDPEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZB7</accession>
    <name>M5FZB7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_94852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628756.1">
        <property type="nucleotide sequence ID" value="XM_040777249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZB7"/>
    <dbReference type="STRING" id="1858805.M5FZB7"/>
    <dbReference type="GeneID" id="63692311"/>
    <dbReference type="HOGENOM" id="CLU_073129_1_0_1"/>
    <dbReference type="OMA" id="VFQSTMG"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF21">
        <property type="entry name" value="DNAJ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="233" mass="24948" checksum="9CBDFEB0F731FBCF" modified="2013-05-29" version="1">MAAFVNYYHILHIERSATTDQIRTAYKKESLRTHPDRLPPSSSPQDRASSTQAFQAVADAYYVLSDPGRRRDYDALLDARAPAGWGEGASASASFFEQFASAFASGASHPPPPESTTTNDSSPEPEAPPSSWSSHQPDPNTTFSNVFADLLTPEIAPHLPYWTWLGSLSGAGLGYIIGNVPGLMLGAYAGNRLGKVRDAKGKSVAEVFVALPGARKAEILKVLAMKILGSTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZF5</accession>
    <name>M5FZF5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628147.1">
        <property type="nucleotide sequence ID" value="XM_040770207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZF5"/>
    <dbReference type="GeneID" id="63685269"/>
    <dbReference type="HOGENOM" id="CLU_821411_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="338" mass="36395" checksum="C0C1AFAD2402FF93" modified="2013-05-29" version="1">MPSPRLILGSPFKGDTWHELMLQMIGGTMPQITDATCKWSEGMQRKRKAHAEIIAYMERLENMSPGEEEFQESCRVARERRGLPPCVYPMPEAPVEIIAGPSQPTPHTQSAQDEERRLISTPTQEQAILVTGAGIHPPVAVEQAFSVHGNIPRGNEQEAADVSLASTTYEDGGSLYAYDSGTIFEDGGTIQSHDSIPTDRTPTPTGSSMYRLPELSFTGSALGLSFDSLETIADPGPTQVVLIASSSTTSLPISTNGTISSAGYASDTEDLETVEEERGGVSGRKSSERRNGLFQLHQMSADRDRQPKRAHAPGRYWIPHVRASAASSAGERACGPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0R8</accession>
    <name>M5G0R8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HlyIII-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_25154</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624290.1">
        <property type="nucleotide sequence ID" value="XM_040774033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0R8"/>
    <dbReference type="STRING" id="1858805.M5G0R8"/>
    <dbReference type="GeneID" id="63689095"/>
    <dbReference type="HOGENOM" id="CLU_021163_0_0_1"/>
    <dbReference type="OrthoDB" id="5585746at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="566" mass="62560" checksum="2FF1A87ECAE9E9D0" modified="2013-05-29" version="1">MAASSSAIPELDSPTPSLSSSSSADEGSYSFTAHPPSTMASASAPDPPSLTALLLSLRVMLLSHLADVESRIANFDASSLPKLFGGSPSDILENSPAAEDNIGQDGALRKSRRMSRTASEEISTLLESIRADVARHLPALDIDFELPSLPDFDLPTLPALHLPESLFDTIRAHSPSLPSNFIPSLKHRLQSLASLAATPPQLQTLLSYAEKVPLAMDEFESSSEEELLSKREGRAKGEEGVSATSDEEDVHEQVPLIVGGSKTTRAEVRRALVRSINGDRLIRFEDLPHKWKNNEFIHTGYRFIPFSRWPLLAASLFQWHNETINILSHLLPTVLFPLISLVPIPNLPLPTYFWPSWLEMPDVTIDVLPYWYFWSAAACCLACSVIWHTMAGCSDMHVCEWGARVDYVGIGWLISASITSAIYYGFYCDPHTAAIYAAFSILTGALGTVLPFMHWFNQRKNKKWRIAFFVTCALSALLFFAHLSLEHGIHATGEFYAPIVPSVAAYTFGLCFYAWHFPECAFPGRFDYIGASHQIWHISIVAAIWLHYRAIASWHVGALEYACAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Y9</accession>
    <name>M5G1Y9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-hydrolase/oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_87462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631090.1">
        <property type="nucleotide sequence ID" value="XM_040776810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Y9"/>
    <dbReference type="STRING" id="1858805.M5G1Y9"/>
    <dbReference type="GeneID" id="63691872"/>
    <dbReference type="HOGENOM" id="CLU_051050_0_1_1"/>
    <dbReference type="OMA" id="DCILLSH"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF7">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="34502" checksum="8E4D1C39C013EFDD" modified="2013-05-29" version="1">MALQTVLDLPLTREATFQGSPAADPPSYATQLLPGKDNNSRNSVQFVGNATCILEIKGVRVMTDPNFLHQGDHVHLGPGVTARRMHDPAFNLEECPPVDFILLSHLHEDYFDLVVAEKLRRSIPIISTPHATSGLANQGYTHLITLDTWKSALITHDGIKKFTITSMPGKHTIGVFNEMVEVMDAIPPVMGSLIELLDEDNKVEFTIYISGDTLFCEKLKDIHTKHPHIDLCLLHLGGTTIPVINVMVTMDAVQGINLLHVVNPDTTIPVHFDDYDAFLSPLEDFKKLVEKEGWSDRVIYLDRGETYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G6</accession>
    <name>M5G2G6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624855.1">
        <property type="nucleotide sequence ID" value="XM_040773889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G6"/>
    <dbReference type="GeneID" id="63688951"/>
    <dbReference type="HOGENOM" id="CLU_787601_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="39735" checksum="2E41874BFFE513EF" modified="2013-05-29" version="1">MKSSPPKFETGKLMPRAYPRRPRRGQCEDKENTRPIISVPSQRTQSVQAEETDVFMHPRLIRPPSGQMIDSLPRSRTPFRPAAPEPPRLTSLTRRPVSPTPVRKRPASIAGYQDLVHTFHPFPASKAAPAQHVWATREDEDIRSPSQRVHQPVAEHAAAELERSLNPSNCFTSARQRPARQMSSPSVGVSDESKNIPVSEWQPAIRSASAYPQAVASPCNDPTLRNSSKQIRRGGSLALKECPILQDVSIYQADGRARRGNHTRSMDLDQLRGIWETRDRTESNDFPTKTSTRELKQSVMGTHHRSWIATPVNHVRQAKINKVDGWSLNNPEAEFVIGEWKEEEDTWEECSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2R3</accession>
    <name>M5G2R3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_78925</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629404.1">
        <property type="nucleotide sequence ID" value="XM_040776365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2R3"/>
    <dbReference type="STRING" id="1858805.M5G2R3"/>
    <dbReference type="GeneID" id="63691427"/>
    <dbReference type="HOGENOM" id="CLU_012393_2_1_1"/>
    <dbReference type="OMA" id="DQCDAFY"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000117">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="11">
        <location>
            <begin position="180"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="14">
        <location>
            <begin position="289"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="13">
        <location>
            <begin position="449"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="131"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="602" mass="66823" checksum="0569BC7F27C6A466" modified="2013-05-29" version="1">MSFNLTPDACSQLMQDAPPDFSPVLQILSVKQVNTGPAGPPRMRVIISDGQHFTQAMLATQLNHLTDRPEEDTPAELDKNSVIKLEKFASNSVQNKRLIILLDLSILGNAGQKIGNPTSYDVAKAESHAQAISAPAPAAPPITVQKSHQPAPGGTRSASMPKNGGPIFPIEGLSPYQNKWTIKARVTNKSDIRHWSNQKGEGKLFSFTLMDETSEIRATAFNQQVDEFYDMIQEGKVYFFSKGRIGPAKRQFNNVSNLYEITFERNTEVEPCLDAGDVPEVKYQFVTLEGLQEVPKDATCDVIGVVTEVGELGEILAKATGRSVPKRDISIVDRSGFFCRLTLWGKSGETFQAPDQPIIAFKGVRVSDFNGRSLSFQSSSQMSINPDIPDAHQLRGWYDSIGNNQPHHTFSSAAGAGAGGDRGQFNRNELKTIAQVKDEGLGMGEKNDFFTTKASVIHVKQENFVYPACRSEKCNKKVVQTSDGRWECVSCGLTFDEPEYRYLLSISVADHTGQAWLSAFNDAGDMLFEMKAGELQNLKDTDETHFSKVMSDVRSKMYNFSCRARQDTYNDQTKVRYNITRMTKIDLKTEMKALVDNMKAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G360</accession>
    <name>M5G360_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Purine nucleoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_89831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627199.1">
        <property type="nucleotide sequence ID" value="XM_040776935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G360"/>
    <dbReference type="STRING" id="1858805.M5G360"/>
    <dbReference type="GeneID" id="63691997"/>
    <dbReference type="HOGENOM" id="CLU_031475_1_0_1"/>
    <dbReference type="OMA" id="WAHYLVE"/>
    <dbReference type="OrthoDB" id="2331083at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009486">
        <property type="entry name" value="Pur_nuclsid_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643:SF1">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06516">
        <property type="entry name" value="NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="291" mass="32091" checksum="82C153D034ADD64F" modified="2013-05-29" version="1">MFTPEEGAWLVPLDLKYNISVPGLSMLYPHVHCDDKGWICQMTTGESEINAPASTTALFFSPYFDFTSTYFMIAGIAGGNPYYTTTGSAAFARYSVQVALSYEIDPRELPSNWTTGYFGFGTTAPDMYPGMSNWYGTEVFELNTNLLPRVMDLVKDVKLNDTADAAAWRSKYDFAPANLPPTIVQCDVATSDVWFSGAMLSEAMGNITEVWTNGTGKYCTTAEEDNATLESAVRAHLAGMVDYSRFILLRTGGFEVAITNIFMAGWPVVKEIVYDWDAFTRGYGDVLGSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G377</accession>
    <name>M5G377_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625090.1">
        <property type="nucleotide sequence ID" value="XM_040767608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G377"/>
    <dbReference type="STRING" id="1858805.M5G377"/>
    <dbReference type="GeneID" id="63682670"/>
    <dbReference type="HOGENOM" id="CLU_831613_0_0_1"/>
    <dbReference type="OMA" id="WICELHE"/>
    <dbReference type="OrthoDB" id="3337671at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="334" mass="37341" checksum="108C4E28D9C48BC0" modified="2013-05-29" version="1">MLGHFFLEAVEILRTAYPEKTAYLTSVSECAVQGYSSTTYFVTFTEEEGVSEMVLQLRRPEHYLNVSVLEAAREVLGELVPAARLLMEYDRGENKLLAYEMSRIPGMCLSEFTGRKEYVDCLPVTAHSLGSMLGKCCMPGRVAPAEFTRAVRNRLEKAVKSSDPLLASYIDDFRELLDTKQVLDCLPMAIGNGDLQFSNILVDETGQVTGLVDWEDELHQAPLGFDLCFLQWLLGDFRALLTGGKYTLYPNASEIEAGFWGGFFAHLPPAMRVTNTFIGQLEQVMRFGAVFFHAIDGRCNLPSCIGLLRLQLDYTIPVQRLGLNFVQNSGMILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3B9</accession>
    <name>M5G3B9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_75584</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631595.1">
        <property type="nucleotide sequence ID" value="XM_040776143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3B9"/>
    <dbReference type="STRING" id="1858805.M5G3B9"/>
    <dbReference type="GeneID" id="63691205"/>
    <dbReference type="HOGENOM" id="CLU_003041_1_4_1"/>
    <dbReference type="OMA" id="EMAHSIM"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000759">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="166"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="373"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="63"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="553"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="589" mass="64915" checksum="AAFE0A498A9420DD" modified="2013-05-29" version="1">MDAFALLSRGGTQFDKRRFNKEVNLFSGHKKHAETVASTSHTTDEFPEELDFFKYAESGVLGTKGEGAANGKSRAADSERTVGVERQSQGSGWEGSAKRGTKRKRSLEPERTITSARRVRCTGESVPTPIHSFVSLQDRYGLAPELRKNIAEKGYLTPTDVQTQCIPVLLEKRDLAAIAPTGSGKTLAYLLPVFCLLGAPGRSGASEKQAGARALIVSPTRELAMQIHNEALKLAKGRKWKVVVLNKATGNALRDKAARKKVDLLITTPLSLVSALDEGILNLDNIRHLILDEADRLLEEGFLKQIEAILAACSYPEIQKAVFSATLPAAVEAIANTFLRRPIRVIVGVKDSATDTIHQELLFCGSEIGKLQALRNLVVEGIQPPVLIFVQSIERAQELFHELLYDGLNVDVVHSERTKAQREDAVRRFRKGEVWVLIATELMARGMDFKGVNLVVNYDFPQTVQSYIHRIGRTGRAGRQGKAVTYFTKEDAPYVKSVANVLKASGQDVPQYMLDLPKPSKLKKRELKRHPIERKDIARAAGAGVGRNLANKKRDMICASKRRKTEPAGDKGGKGDSVVRRQVVLTEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G488</accession>
    <name>M5G488_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_114890</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630393.1">
        <property type="nucleotide sequence ID" value="XM_040769904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G488"/>
    <dbReference type="STRING" id="1858805.M5G488"/>
    <dbReference type="GeneID" id="63684966"/>
    <dbReference type="HOGENOM" id="CLU_117291_1_1_1"/>
    <dbReference type="OMA" id="MKDHFRS"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="14253" checksum="6EBCBC6AD94EB269" modified="2013-05-29" version="1">MGRLRRSRTHKAQRDVHRASRTRARTKDLDQIQADLLPARRALLEAQPIDPDLPGLGQHYCVECARYFESDAALKVHWRGKLHKRRCTRLREPAYTIEEAERAAGLGRETRTRKPEVAMEQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4E3</accession>
    <name>M5G4E3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like 1-activating enzyme E1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_90739</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625510.1">
        <property type="nucleotide sequence ID" value="XM_040776971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4E3"/>
    <dbReference type="STRING" id="1858805.M5G4E3"/>
    <dbReference type="GeneID" id="63692033"/>
    <dbReference type="HOGENOM" id="CLU_002556_4_1_1"/>
    <dbReference type="OMA" id="EFFGQFD"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="7">
        <location>
            <begin position="22"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="339" mass="37071" checksum="D7195FD0FB83A98D" modified="2013-05-29" version="1">MASAILHDGKETAITEDEAALYDRQIRLWGFDAQTRMRNASVLVINLRGTACEVIKNIVLAGIGTLKILDERVVEEEDLGAGFFFREDDVGKKRVDAALPRIAALNPLVNIVSLSSPLSLSDDSLHALFHGINLVCATDCDRVTYEKLDEACHKSGKQFYCGGTMGWYGYAFCDLGQHSYVSQDQTKPNSPQTHKTFTYVPLSTALRATWSHLTKRDTKELNPAVVFSILAVWEYQARHSSLPEDEAVVPELLQMGNELLGPAQINKLVLKTLPSEHVERLSTIAAAELSPICAILGGFLAQDMLKAIGGREAPMANFFTFDGILGGGTVCRLGMKDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4F1</accession>
    <name>M5G4F1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Family A G protein-coupled receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_24231</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625520.1">
        <property type="nucleotide sequence ID" value="XM_040773602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4F1"/>
    <dbReference type="STRING" id="1858805.M5G4F1"/>
    <dbReference type="GeneID" id="63688664"/>
    <dbReference type="HOGENOM" id="CLU_054785_0_0_1"/>
    <dbReference type="OMA" id="MFLGMLY"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF2">
        <property type="entry name" value="BACTERIORHODOPSIN _OPSIN, NOPA (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="331" mass="36013" checksum="4D6886D63267D592" modified="2013-05-29" version="1">MEFHQVVNILTSASLASATATITGTATLPEPIPSPTPSPHLPPQAVTFLTVGTFGRVVSWIAVALYTLALLCFLYSTLHRPTHKRLLPILLTLISIVSLAAYYSYATNLGFAFQFLGTPDKLIARQVFYGRFVQYAATTPLILVTLGSFAGLQAYRIVLLAITGFALEVFGGIGTAVIHSGFHRGHLHTHHAAWGWLLLSLLSFLYPLLTLFIPARTSVAQRSPALLRPYTILLSLELLFFVPYPLFMLLGSWFNLLGPKAEFLANTLLDILTKPVFGWALLFVLYRHPEGEVLMTPTWAGEAGYEPVPQAVEGEEVQVAVAPAAAVEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4W2</accession>
    <name>M5G4W2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DRMBL-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_83348</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625690.1">
        <property type="nucleotide sequence ID" value="XM_040776622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4W2"/>
    <dbReference type="STRING" id="1858805.M5G4W2"/>
    <dbReference type="GeneID" id="63691684"/>
    <dbReference type="HOGENOM" id="CLU_005260_4_1_1"/>
    <dbReference type="OMA" id="YMIYGVP"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12650:FF:000007">
        <property type="entry name" value="DNA cross-link repair 1A protein, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="185"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="484"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="648" mass="71288" checksum="C50718A9CB2A0D22" modified="2013-05-29" version="1">MGDDELVPDEGGVEFEGDDDVEEIGDFEQDAADVDSESQDGAAARTSGCPICGAIIEDLAKLQLHVNACLDTPPVASSSFPPAPKTRYQPKQKPISARSPSPLKPLPIDPSYTLPSPSSTLAPPPRGNPSAFSVLMSQNKDHLAWAAAEQHEVRGPRSGAGRRKAPFYKVMQGMPIAVDAFRYGKIPGVTAYCLTHAHSDHYTNLSSSWKHGPIYCSSTTANLIKLNLSVAPEYVHPLPLNTPTTLPNTGGVQVILLEANHCPGSVLFLFIGRQTVNAGDSPISSPFVGSQRTFRYLHCGDFRACPAHALHPEIKGKKLDLVYLDTTYLNPRYCFPPQRQVVDACASLAKRMVLGTEEEKEDKPKGVTQSVLRGWFKAEPKEEAVEPGLEIEEELALDPEEELDVTFNGDLPPPLPPPPKPLPAPHPTSAAEESKPSTPGKTLVAIGTYSIGKERIVKAIALALGSKIYCDARKRGLLLAQDDPELHSLLTTDPYSCQVHLLPLQSITVDRMQDYLEQFKGLFDRVLGFRPTGWTYVPPAGMDVMPDVSRVIVRDQKRVFDETALKPTRAASQKYMLYGVPYSEHSSFFELTCFALSVDVGKIIATVNVHSASSRGKMQKWFEKWDVERKRRRNAGHEVVQYRTVDYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4X0</accession>
    <name>M5G4X0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627799.1">
        <property type="nucleotide sequence ID" value="XM_040768617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4X0"/>
    <dbReference type="STRING" id="1858805.M5G4X0"/>
    <dbReference type="GeneID" id="63683679"/>
    <dbReference type="HOGENOM" id="CLU_062645_0_0_1"/>
    <dbReference type="OMA" id="GRYFQLK"/>
    <dbReference type="OrthoDB" id="2107885at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="318" mass="34317" checksum="CCA0F175D269D636" modified="2013-05-29" version="1">MSQSSPTDVHTRRRSHPPPTPGTTSNQPQPQAHAASASAAQAQLSLSRVSEIAQQGVTSKAWLYPVKGILYLIGHPSLLRPLIPTIALSLFVSLILTVSIFGAFYLPLAGLLAVFNGPIGFLSAATVLLSLSGTAVNALARSLFLQQALERVFDQVLLDHSLLILLSHGRELKKSHTGRRLGAVLTKPLARFSPRAILTYILSLPLNLIPLVGTVFFVLYNGVRTGPGWHERYFVLKRLDKREKEEWANIVPEDSFGAAAIVLNMIPLMSLFFTFTTDVGAALWACDEEKLAGKAEGVLAEGRTATAVPQTSAGHVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Z3</accession>
    <name>M5G4Z3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glia maturation factor beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632230.1">
        <property type="nucleotide sequence ID" value="XM_040771695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Z3"/>
    <dbReference type="STRING" id="1858805.M5G4Z3"/>
    <dbReference type="GeneID" id="63686757"/>
    <dbReference type="HOGENOM" id="CLU_087056_1_1_1"/>
    <dbReference type="OMA" id="EWKMLYA"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071846">
        <property type="term" value="P:actin filament debranching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034316">
        <property type="term" value="P:negative regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="139" mass="15571" checksum="C1FD2AC90775E251" modified="2013-05-29" version="1">MSGTVDIPTELKNSLRKFRFARRSAGNAALIVKVNKSKLIMEEVEVFDSISVDDLAEELPENSPRFVLMSYELEHRDGRKSFPLILINWAPSTCEISMLTLHASAFLQFQNAADVSKIIEIRDGTESLTKDAIDAKLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5K1</accession>
    <name>M5G5K1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WSC-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_56734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625935.1">
        <property type="nucleotide sequence ID" value="XM_040775390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5K1"/>
    <dbReference type="STRING" id="1858805.M5G5K1"/>
    <dbReference type="GeneID" id="63690452"/>
    <dbReference type="HOGENOM" id="CLU_063916_3_2_1"/>
    <dbReference type="OMA" id="GWRINIY"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="74"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="17632" checksum="7ADEA8182172BBB1" modified="2013-05-29" version="1">MTVAICQSYCLSNGFNFAGVEDGNECWCSNSIQNGASAASSSDCSTQCQGNANEKCGGGWRINIYQYIPPNGPRWSSVGCYVDANNRALPNYAESSSSMTTEVCQSFCGNAGYSYAGTEDGNECWCANSIQNGATQASSADCSTPCVGNSGGAYPGSKDFIAQLMNWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Q8</accession>
    <name>M5G5Q8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628029.1">
        <property type="nucleotide sequence ID" value="XM_040773010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Q8"/>
    <dbReference type="GeneID" id="63688072"/>
    <dbReference type="HOGENOM" id="CLU_2739958_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="71" mass="8108" checksum="8E881C757502D7EC" modified="2013-05-29" version="1">MDSEGAQNKSWLPDMQEFVFSMDMPTDRTLRKAARLPWERVGRHESERRETAISDRHGGKGGDSTGGNHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5W8</accession>
    <name>M5G5W8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_20752</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 10 11">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 11"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631013.1">
        <property type="nucleotide sequence ID" value="XM_040772065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5W8"/>
    <dbReference type="STRING" id="1858805.M5G5W8"/>
    <dbReference type="GeneID" id="63687127"/>
    <dbReference type="HOGENOM" id="CLU_018316_2_0_1"/>
    <dbReference type="OMA" id="YIQYEIQ"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52049">
        <property type="entry name" value="ULD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="12">
        <location>
            <begin position="6"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="9 10">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU04119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="35972" checksum="FCEE2DE005B01125" modified="2013-05-29" version="1">MSDESGWSLTESDPAVFTALLQSLGCNTLIVDDLWTLDDPALLSSLQPIHALIFLFKWIGGTEDEAADGELKGGGRYDEAFPGFFAHQVVNDACATIAVLNGVFNIPSVPMGPDLSQLREFSAGMDPLMSGYSITNSAAIRNAHNALSSSANSPFSIDPSLYDQNEKEDAFHFVVYVPVAGQLYELDGLRRAPVQHGGWEGGEGWLDVARRTIQRRIEGYPPGTLQFSLLAVRTDNLPGMEAQLEQARAAGDEHLASELVHHIYAEKSKRAEWEFENSLRRHNHVGLIHSLLLALAKAGGLDTAVQKAKQKMIEARQKAAKSDTKMEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6E6</accession>
    <name>M5G6E6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit DUO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein DUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_105327</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DUO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631158.1">
        <property type="nucleotide sequence ID" value="XM_040768076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6E6"/>
    <dbReference type="STRING" id="1858805.M5G6E6"/>
    <dbReference type="GeneID" id="63683138"/>
    <dbReference type="HOGENOM" id="CLU_959850_0_0_1"/>
    <dbReference type="OMA" id="QWQGASQ"/>
    <dbReference type="OrthoDB" id="5599235at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013960">
        <property type="entry name" value="DASH_Duo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08651">
        <property type="entry name" value="DASH_Duo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="196"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="196"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJU04264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="290" mass="32138" checksum="A95A58B41324B0CF" modified="2013-05-29" version="1">MSLTDSPPTPHLSSQDDLVDLKDLSLSDLAGPDTPRAQKPFSLFAETPDQPPRAQAAGSDQPAASTSRLIEKSIAGKSGLQEEMDGEAERRTRGPRTNRAERLETELFELKQLNQVFSDYLTSLEAAKDHNSRLAAQVDRTNALLDKYVAILGQAQHTQELVLNPEWQGAEADELAILEQRQREHEERVRIAREEKERKEREERERLAKAEREEQEREARERKEAMGSRGRGRGVSGVRGVRGVRGTRGTTTTTAPRGRGVSSTTGDASKPRSSMMPRPSVAAGRGRARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6G2</accession>
    <name>M5G6G2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vps5-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_49189</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU03795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="63689949"/>
    <dbReference type="HOGENOM" id="CLU_022783_1_2_1"/>
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    <dbReference type="OrthoDB" id="271164at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="GOC"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="term" value="F:phosphatidylinositol binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:protein retention in Golgi apparatus"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="10"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
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        </source>
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        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU03795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6K5</accession>
    <name>M5G6K5_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11392" checksum="5A28122C9D68F097" modified="2013-05-29" version="1">MPVRTGKSPGSSGYWVLEIWTGDRPLPPPLPQSPQSPPPLQCLPPLPQSLSLRLPPPLPLPPQAPPTPPSQPSPTQPQPSRTSSPFPLEQGTVGTDYGHGGLGEEEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6S5</accession>
    <name>M5G6S5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_37360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628419.1">
        <property type="nucleotide sequence ID" value="XM_040774430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6S5"/>
    <dbReference type="GeneID" id="63689492"/>
    <dbReference type="HOGENOM" id="CLU_867551_0_0_1"/>
    <dbReference type="OMA" id="QHNDINP"/>
    <dbReference type="OrthoDB" id="426133at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052762">
        <property type="entry name" value="PCW_deacetylase/CE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834:SF2">
        <property type="entry name" value="ESTERASE, SGNH HYDROLASE-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G00620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="321" mass="36731" checksum="7CBF7B10F7E126C4" modified="2013-05-29" version="1" fragment="single">HGRWDVDNTSWWAGSGFDIVATNLTTVAVICGNLNSKNLPVGVSINYATYETHIFNAGLNRIPIPAGTNSQRTVIRFAVEAWEFANLHLLSINLNEGAVAVPYKSQKLKFQFIGDSHSSGQYCKRGVIDCFDWIVAEELRAEKDVNAQPGAALTDIECWGNVHGLSFQFFKTEDTRYYYNQKHNYVTDWDFSRDDPPTHLVIFVGANDGSERYNVPVEEFTETYKKFVDLLREKYYKDQPIFIFTNWGKFKETGAMRSYYDNPSPYHAVQAHRVALGDQNVFVVDTHGWIGWTELFTDNGHCHEQGQKVVASKFLAWLKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Y0</accession>
    <name>M5G6Y0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628469.1">
        <property type="nucleotide sequence ID" value="XM_040772906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Y0"/>
    <dbReference type="GeneID" id="63687968"/>
    <dbReference type="HOGENOM" id="CLU_2800899_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="68" mass="7239" checksum="C0BD723C8CA2CF5A" modified="2013-05-29" version="1" fragment="single">MLFCIYSASGFHSLQTTTPIIPQAAGETRAPHRFLSQIHSTLVILPSTPRGLGCVYDSVSSTKAGICC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G722</accession>
    <name>M5G722_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631413.1">
        <property type="nucleotide sequence ID" value="XM_040768111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G722"/>
    <dbReference type="GeneID" id="63683173"/>
    <dbReference type="HOGENOM" id="CLU_122941_0_0_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="16541" checksum="E3A0B2CD80DA5058" modified="2013-05-29" version="1">MASPASQRIVKTSSSSSGVDATNLFNHPVLAFDTGDNQLLGLPHDDWLTLMSLLGAQGSDSNGNFLIPCGSTMTYNFFGTKNREYTFSIADTTTNNGQGFCKPTVIDSGSTTNWITGMPFLHQYYVAFHYTANMMGFGTRNLGASAAQSKPFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G735</accession>
    <name>M5G735_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_36223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628519.1">
        <property type="nucleotide sequence ID" value="XM_040774406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G735"/>
    <dbReference type="GeneID" id="63689468"/>
    <dbReference type="HOGENOM" id="CLU_003703_10_0_1"/>
    <dbReference type="OMA" id="SHSEYCQ"/>
    <dbReference type="OrthoDB" id="3257768at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="57" mass="6561" checksum="AAE5FE62C5948F07" modified="2013-05-29" version="1" fragment="single">LEWVVPKMHAVSHSEYCQYHYSLHFKEGTGRSDGKGVEHPWSELNQLGGSTREMTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B5</accession>
    <name>M5G7B5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-malate dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="4">1.1.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_76405</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-malate + NAD(+) = pyruvate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:18365"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.83" evidence="4"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630979.1">
        <property type="nucleotide sequence ID" value="XM_040776199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B5"/>
    <dbReference type="STRING" id="1858805.M5G7B5"/>
    <dbReference type="GeneID" id="63691261"/>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_1"/>
    <dbReference type="OMA" id="MRFAFKL"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046553">
        <property type="term" value="F:D-malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050501">
        <property type="entry name" value="ICDH/IPMDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011829">
        <property type="entry name" value="TTC_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02089">
        <property type="entry name" value="TTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275:SF1">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="11">
        <location>
            <begin position="6"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="38862" checksum="3A946E2810EC9623" modified="2013-05-29" version="1">MVNAHKIACIPGDGIGIEVIEASIKVLEVMQPLFGFKFEYTDLPWSSAYYKKNGRYMPPDALEILKAHDAIFFGAVGAPDIPDHISLWELLLPIRQGLQLGSNVRPSKIFKGVKPPLANCEVGDLNWLILRENCEGEYCGQGGRSHTGTPYALGTELAVFTRFGIERHMRFAFELARQRPRKMLTLVTKSNAMRHGMVLWDEVFYDVAKDFPDVKWDKMLVDAVTIRMVQKPKSLDVILCTNLHGDILSDLAAALSGSIGIAPSANVDPERKAPGLFEPVHGAAFDIMGKGIANPIATFWSAAEMLRWLGEEKAADGLMSAIEHVLEHGPLTGDLGGKANTEQVTQAIISALKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B7</accession>
    <name>M5G7B7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628614.1">
        <property type="nucleotide sequence ID" value="XM_040772699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B7"/>
    <dbReference type="STRING" id="1858805.M5G7B7"/>
    <dbReference type="GeneID" id="63687761"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_1_1"/>
    <dbReference type="OMA" id="ADCVICA"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="473" mass="52631" checksum="D43EAAE66DB58D18" modified="2013-05-29" version="1">MVSPTQHPPSGIKVLIVGAGFGGITAAIECHNKGHQVIVLEAFPELKILGDVISLGPNAGRIIERWGNGSVARELLPITHNNKELVMHRFDGPVVTRTPVTGLKFGSPAFNGHRGELHRCFFRFAQQEGIDIRLNSRVVEYWEEPDKAGVVLESGEGLEADVVVGADGVKSKARQLVLGYDDKPRSSGYAIWRTWFTSEELAKDPLTKFFSAEDTHHGWIGPEVHFLAASLKGGKDVSWVCTHKDEKDIEESYQFPGKIEDVLKVVGDWDPVVVSLVKHTPEKNMVDWKLVYRDPLPTWISKGARICILGDAAHPFLPTSIQGASQAMEDGVVLACALFSAGKSRVPLGVRAYERIRYERCRRAQLMGESTRDKWHKADFDNLMSSEENMRAMDLPHPPWLFWHDAEKHTLDVFPEVAKDIESGKFGTDEIGFQTSVLRRENGKIVVGNRSFEEPSGEELVQVLVKEQVTAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7C7</accession>
    <name>M5G7C7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Sulfate adenylate transferase</fullName>
            <shortName evidence="9">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET3</name>
        <name evidence="13" type="ORF">DACRYDRAFT_114507</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="9"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7C7"/>
    <dbReference type="STRING" id="1858805.M5G7C7"/>
    <dbReference type="HOGENOM" id="CLU_022950_0_0_1"/>
    <dbReference type="OMA" id="MEMRYAG"/>
    <dbReference type="OrthoDB" id="468at2759"/>
    <dbReference type="UniPathway" id="UPA00097"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010134">
        <property type="term" value="P:sulfate assimilation via adenylyl sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000003">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000802">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000052">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="12">
        <location>
            <begin position="12"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="11">
        <location>
            <begin position="183"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="10">
        <location>
            <begin position="404"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="9">
        <location>
            <begin position="404"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="206"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="300"/>
            <end position="303"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="443"/>
            <end position="446"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="9">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU04095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="583" mass="65225" checksum="633BB8B50E71E78C" modified="2013-05-29" version="1">MPHTQIEPINNAPHGGVLKDLVVRDEPMREKLLLEAERLQEIILTDRQICDLELILNGGFSPLEGFMNQADYTSVVETMRLADGTLFPIPITLDVSAGDVKTLGIAPNARIALRDPRDDTLLAVLTVQDVYTYNKKNEAVKVFGADDIAHPAVKYLYDRCKEYYVGGKLQAIKLPTYFDYVALRYTPTELRAHFNKLAWRKVVAFQTRNPMHRAHRELTVRAARLRQANVLIHPVVGMTKPGDVDHYTRVRVYQSILPRYPNGMAHLALLPLAMRMAGPREAVWHAIIRKNFGATHFIVGRDHAGPGKNSQGKDFYGPYDAQELVTKFQEELHIEMVPFQQMTYVPSLDEYQPVDEVVPGTQTLDISGTELRKRLRTSAPIPDWFSYDPVVKVLRKSYPPRDKQGFVLFLTGLYNSGKDTIARALQTVLNQQGGRSVSLLLGETVRSELSSDLGFSRDDRHTNIQRIAFVSAELTRAGAAVIAAPIAPYADSRKAAKETIMSTGGSGANFFLIYVATPLEHCEKHDKRGNYAKARRGEIKGFTGIDDPYEAPTDADLVVDISKQTVPEIVHNIVLLLESSNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7J0</accession>
    <name>M5G7J0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Csf1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_101324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626635.1">
        <property type="nucleotide sequence ID" value="XM_040767545.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G7J0"/>
    <dbReference type="GeneID" id="63682607"/>
    <dbReference type="HOGENOM" id="CLU_000463_0_0_1"/>
    <dbReference type="OMA" id="YGLEWFI"/>
    <dbReference type="OrthoDB" id="10051416at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006113">
        <property type="term" value="P:fermentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029636">
        <property type="entry name" value="Csf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048636">
        <property type="entry name" value="Csf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085:SF3">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21678">
        <property type="entry name" value="Csf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 N-terminal" evidence="3">
        <location>
            <begin position="39"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2480"/>
            <end position="2513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3252"/>
            <end position="3278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="3366" mass="375229" checksum="4888601CF4BD36B7" modified="2013-05-29" version="1">MSLFTIPHLQQREVTLSDLDQTPLNWLLLVIAVVIVLCVLFFLFYWNRLLARFVSLLLRWRYWKSANTWIECESVQVSLLSGRLFLKDVRYYSRNQAIRVLKCHVTWRYWIWRTRDEVDDVLHGEGEKGDDAAPVSGGRNLPCRIFVYMEGVEWFLYNRTPAFDAIVERLAEAARREQEQVRLGGEYPLSPIQTGDKERSSLSVPPAAATHSTSILLHAPTVIQGAFDRSTMFLRFLLRLIPKLVPALGLRDILPIDIRVLTGAITVGNDATPYLLVGSFKSGRGMWGVGPARSRLDVHRQVVDATLTGVKLVSRTNPDWSGEIGQEGLIAYSDALKDPTIGAGPLHTPSSLLPPAFQHIFAPLLKRKRKSPSPPSQATAPIQVWKGLDRFRTEEERTRGEMRHEQEYAKVPGILEARELGIGWYADVPGPVPDTGLQRSGSRRMRDTGPSPAYDRDMDEIGNGDLPPEWGVDISLRDATVTYGPWMDRQRSFLQSVFIPPFWADNRPTHRLRPGDTRLATAMRVFVQLEGTTTLRLPTRETSKDWKYDKVGLAPAEADADERAYGWINITSHGLGSVSYILPAVVGPQGYDTTVEVDLSDVGITSSVNYANFWQSQRVRVGLTIPSPLAWKALRTWMIEVDFSHPKIFFLRDHAFLIQDLIRDWNSTPASEYAVFVPTRYELSLRLREYTLNLYANDFNVVSKPLSAEDNVFVSASGPLLELSLSIDSTRWRPQCSEVPFTIDIPDVSFHMSFPLWNTHGAFATPCTTHFGTSPALAISGSYCWFASTNREFVDRLRLDVRAERTVFKCFGWVIRHCMILRDNYFGQFTNFTTLEEYQQKRVQGRVGDPVEAKYRPGKSNPLDVEVSISVQDGLVLLPQEVHEFTAAVALDIPEFEVSIDVHETHMGLQICVPPVRLLPVDNPEEWLTDRPQINKSECMVLEGLNIACNRLFGPQPRTATYLCLWEMSIGALRGCVPLSFASCLNASMQAISYTFSDVANSPDPSLDVAVSSDVTFLKLVMAPVELLFQCGKSALQVRTLDKLMLDYTDLPRPTYSRTVSLMASFSARALIPSDLLPDIWYETATITAGMRGEFYFAPEGWKEKAEAQTRFVAQQDAMTHRALFVYAPSQEGRAFSSWRQHGMYFLTYPRSLDEAGGAWTNARASYAYAFASSEDSLHGSAEFHSMGGRTPGRAHIGLPTPTATYFDAEDVLERDETSTDESDDEESDTRSGATSDHTGSRASHRRRENWPLGESGLHSILKPFRLERNPNSYISTLTPVEHWGRFPPLLPRSHWSKEQLLQSQAGFDHELANTTMCLDFQDPVDILITPHVTQFIEDLYSTANIAVCSSDREMDVLMLDQLSMSQSTGVKKASSTALSIQVHSVALRTLQLGLVPNERDHHHHSRERRKRQDYYGTMHHVLTICDVSLGDSAFLLAFSLDSAAIQCNTRFGFPRMCLWRSTGNDWAKSAADPASMLSRLSFPVEFSQVLELSTEGIQILGGTNSTGLTANLGLLPCYMNFLDIGAETAIATATELNNALRRAVSIRDHALLRTQSRARFLLWTVLQFAEDRTITTDPPFLNLTTFLVQHGRPGQRRSDNGWRILAHIRHCLRLMPATLRDHLNRSINSEITLSDSQTEVAMHREVLSSLKKWRTWEIDLGSPSVQTLLRALFPAVVQLPEPTKDGRLVDLMLGYNVLHITGQEVRVSLVDAGLPEDTLVFLGPLSSTVMTRIEEYNTPEAKTSQENTEPIADPTQQALHLCFDANMEGIDVHLSPDLMTIFQRMLRLRRMFPRKALTSPASVNPPPSSQFRLSDDLRLIIVDLTTSIKLVNMHAAAQRITFDFIVRRLISASTLRLEGERINSNDAAISSTIASEDIVFRARSPQGPPKASSNHRSMAWLSLAKPSINAGFTSANEGDSPSCRIALAFRRIGLSVPHSALRLYKFVEEWRAEYIPTYHSMIRGILAELETEEDSDIATQDAKPWMDIARLNLYFQAAINTIAINLRVLPSTWFSWEYHDIFLHTRTVKGLEPAFGLSGGLDYGVHLESQTIRLVQANASLNEGLPTSAPLITLELPAFDFSGSYSRSIVQSLAVVGYFSIKLNAQIMDDVLVIPSKFGKDVNDILDVISESRKKRARRERSPTSPTRRESFTKEAFLYSVRLLMEGFEVGIEGPSSTQYIETTKLEGHITNRTLRGLSWNVSITDLTLSLAHTTLTTTSQGGIKGRYRSAYMTINVEASNTPPKGAFGKSEPGTDSIAVVVQKIHAVMQAAAIGELGDLLDYYQGEMLIRSEQRAEEITAIKAQTQRVLQTFESQDRGQTIQAARTWFGTRFLYVAVSRIGVSFPLTLDEIGVPSVNSEGPLPVSPAFLFSIMAVTFMSEPNNTGSAGLRDMSFQFVSRFDQSDDKSFEAGTHMTRNSLRFPDMKVDIRALISTRARRIRLLASMTGFDLDLDPTIAPYVFSLIDVYQQGKERLQRLAQPNRPPQSPLLSKTDPVLLRPKGPAPNGPAPAADVKASFEFKTARVRLFPPSIEGATQTTRAKQIAVIRRTGLGINGLPSFPSETLEAETFILPGLTAWCEYAGAVVQLRENSTEVQPALLLLNAVVHPSRNTLKPSLLPFITELAHNIENRLQRAPVPTSSPSPITPLSLVSKDTPPMVAETLAISTVASMQINLSLRIDQSTLEMTCQPHVNVAASVTWESGGFLITISPGAKEYSFSASIAGISCRLRHGYLSENCLEISAQDLAASATFKPILTADGINANVVSVVVNTQAAGSVRFARLQDLLCFKAVWLDSIPIIEASRGSERQGSDEQNAVVAPHSPPLIMCLLMQIRGLQLEADLGQSITRLNLGVDTITFRSKLAADTSELSLQVGTMVLKADRTLSGYANIQGVSFDTVFRQKAFAANHRELRMLDLRIRLEEMEIGLSTDSKKILQFHSSPIDVQVYDDWSLMLENPALFSSNQEVKLNFSVRAETFEAVGTVLTLPRLIALFNRLQALLATQREGAARESEAFRALRSSRVDNPLSDVATAMLASARPKFKEDTCSRAVMILQNMQLEAGRIRLAVFPRSTSDQDMVRFEAKTVSAELSRNALEDGRYHRKLNMHLSSFAIQRLQPRSLTTEEFTAITAIRWFALLKSASEATIFNGPPTRVYMESWEDPKDMRLDYEYDMTYSSLFDKSAEGTVFLALNYALFKWLDNLAQSFQEEMDKVLLKGSGEVTDLPISPASTFRIDETAPVTPVVLGVASSPIAQSRTPTPPGSAPMPSTADLTGPSTKPRRMTYHKITPGNIELPQLTQLGDFTPRSNQLTLVGLRLDAIPKWVHEGATLSLEVMMKALLQLYSQQLRRIRSENPLSPPQSHDHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7M7</accession>
    <name>M5G7M7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thyroid receptor-interacting protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_44804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633085.1">
        <property type="nucleotide sequence ID" value="XM_040774609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7M7"/>
    <dbReference type="STRING" id="1858805.M5G7M7"/>
    <dbReference type="GeneID" id="63689671"/>
    <dbReference type="HOGENOM" id="CLU_028208_0_1_1"/>
    <dbReference type="OMA" id="WEGLWES"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001494">
        <property type="entry name" value="Pachytene checkpoint component Pch2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23563">
        <property type="entry name" value="TRIP13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="162"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="46716" checksum="505490434F317598" modified="2013-05-29" version="1">MRCSITNFGLAIVEVCMKAQSSTASNRVEKSVRTWMMSDLASVIPGTYLEDWRTVGSLRDVVESVYVSETSYPVSSVDLTNSSINIHVYTPNTSEPEELTSAGADEGQTINAATVCLMPSASVEGLWQSLYYGDDVKSRLLNYIYATIRFSRAGVDANVVSWNRVLLLHGPPGTGKTSLCRALAHKLSIRLGKEYPATQLIEINSHSLFSRWFSESGKLVQGLFNEVKELCDDEDNFVVVLIDEVESLTAARAGSVSSGEPIESIRVVNALLTQLDKLKHRKNVLVVTTSNLIDSIDPAFRDRADIIQYVGLPPQDGVYWILRDCLLELIEKKLIAPVPVQKLLDLPEYRLITKMTESRAKEASNSLYSLAARCKGMSGRTLRRLPVLAAAHHLTGADFDPPPPVEVFLEAMAMVVQEGLAHAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7U9</accession>
    <name>M5G7U9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633175.1">
        <property type="nucleotide sequence ID" value="XM_040771542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7U9"/>
    <dbReference type="GeneID" id="63686604"/>
    <dbReference type="HOGENOM" id="CLU_1219659_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="25132" checksum="94F7DC699456B65D" modified="2013-05-29" version="1" fragment="single">MSGGWLFSFNHRQQANERARKRRLHSFPAGSGSDSLHFMIYPSDLEFTSFTLPAEDIVFRCATKWGVSTITRQAAGQSTDLATIEWDYTGKKIRATIQFQGHGKRSLGDFLEPVDDHGIEHQFRAGNRILHCAYTSDRFVLTSPDDVLLGYDTRVPSGFSRHPVPETFDASVDLLDAMGTVFAAYICMERFRLDGRTSITAKPYSQAWQMTGPGGLSLQAPENAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X4</accession>
    <name>M5G7X4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Regulator of volume decrease after cellular swelling-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_104751</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631753.1">
        <property type="nucleotide sequence ID" value="XM_040767972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7X4"/>
    <dbReference type="STRING" id="1858805.M5G7X4"/>
    <dbReference type="GeneID" id="63683034"/>
    <dbReference type="HOGENOM" id="CLU_077804_3_0_1"/>
    <dbReference type="OMA" id="SAFPWEH"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26403" checksum="86D8B9B0D67D90E8" modified="2013-05-29" version="1">MPTVSVSAAPSYITLQEHHNLTSSTPDSFDSIPPVLRHKEDNVSITLDPPLSGLEGENIKGTLYVIESVLVFISTSGSGFQIDYPSITLHAVKRTPSGPAIYCQLDETPAGQPLPEDEDSEMRELLITPESEDSVERIFEALSICAALHPDKNSGDNDEMEDEMFADADESRFETFTGGEEEELSEVGRAALEHLESIIVYPPGMEPPATGRTTRINGAVERETVGGEETHHTQAGDHPDGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G805</accession>
    <name>M5G805_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_23446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626795.1">
        <property type="nucleotide sequence ID" value="XM_040773244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G805"/>
    <dbReference type="STRING" id="1858805.M5G805"/>
    <dbReference type="GeneID" id="63688306"/>
    <dbReference type="HOGENOM" id="CLU_002794_11_2_1"/>
    <dbReference type="OMA" id="LHIEICV"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000003">
        <property type="entry name" value="Elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="17"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="843" mass="93172" checksum="225A7AA43F78BE39" modified="2013-05-29" version="1">MVNFTVDQVRALMDKPTNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAAKKAGEALFTDTRPDEKERGITIKSTAISMYFEVDKEEVSAIKQKTEGNEFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVEGVSVQTETVLRQALTERIKPVVIINKVDRALLELQVSKEDLFQSFSRTIESVNVIIATYQDAVLGDVQVAPEKCTVAFGSGLQGWAFTLRQFAARYSMKFGVDKDKMIAKLWGENYFNPANHKWTTKATAEDGTPLERAFNMFILDPIFNIFKATMSLQKDHLFSMLEKLDVKLLPEEKALEGKALLKVAMRKFLPAGDSLLEMIVLNLPSPQTAQRYRVETLYEGPMDDESAIGIRDCDPKGPLVLYVSKMVPAPDKGRFYAFGRVFSGTVKAGPKIRIQGPNYVPGKKEDLFIKSVQRTVLMMGPSVEPIQDCPAGNIVGLVGVDQFLLKSGTLTSSETAHNIKVMKFSVSPVVQVAVEVKNAADLPKLVEGLKRLTKSDPCVQTWTTETGEHIVAGAGELHLEICLNDLEEDHAGVPLRTSNPVVGYCETVQAESSMVALSKSQNKHNRLYAKASPLDEELTKDIEDNKVTPHEDFKVRARVLADEYGWDVTDARRIWCFGPDNMGPNLMVDVTKGVQYLNEIKDSCVAGFQWATKSGVCAEEKMRGVRLNIVDVTLHSDSIHRGSGQIMPTLRRVTYAACLLAKPALQEPVYLVEIQCPDTSIGGIYSVLNKRRGQVLSEEPVRVGTPMLTVKAYLPVMESFGFNADLRQATSGQAFPQSVFDHWELMSGSPLDKGSKVEEMVKAIRIRKGLKPEIPTLDMYYDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G827</accession>
    <name>M5G827_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_86103</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633260.1">
        <property type="nucleotide sequence ID" value="XM_040776761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G827"/>
    <dbReference type="STRING" id="1858805.M5G827"/>
    <dbReference type="GeneID" id="63691823"/>
    <dbReference type="HOGENOM" id="CLU_014819_1_1_1"/>
    <dbReference type="OMA" id="PLCFYPQ"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140973" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU06366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="544" mass="58765" checksum="AB45448CD0437068" modified="2013-05-29" version="1">MGLVRILGLALVSALIQLDRVAAWEAQCASFTLPSSVGNSATLIAASYYPAGALVNVTSSGGAVTSNSLPAFCRVQLLVNTGTRNMTNTEVWLPDAWDGRFLAVGNGGWSGGMVYSDLAYSGLVNGHASMSTDGGHTSSSLDGTWGLNNPEAIVDYAYLSVHISVVVAKEVVSAYYGATAGFKSYWLGCSTGGRQGDLHEGNRLMSVQRYPDDFDGVVVGSPANWISHLQAWSIHFNLLVSPQNSTSWISAATWALIHQEVLNQCDALDGVIDGLLNDPRRCFFRPETLACRPGQDATTCLSAAQINAVRLVFSDYYETSQTYIFGRLEPGGELAYETGLLGANPVEINTDYFKDMVVNDSNWDYTTLNYSTIQLADQIDTYRLDAVNPDIQTYVAAPHNGKVIHYVSWADQLISPGNSLYYYEQMTAFMNLNTNLNVDDYYRLFTVPGMQHCAGGDGPNGFGGEGQSAAGMPPLQPDALHDVLRGMIAWVEQGAAPNYFIATKYVNNTASGGVQMTRPLCKFPTEIVYNGYGDTNNAGSFYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8C3</accession>
    <name>M5G8C3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631294.1">
        <property type="nucleotide sequence ID" value="XM_040768091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8C3"/>
    <dbReference type="GeneID" id="63683153"/>
    <dbReference type="HOGENOM" id="CLU_767315_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="361" mass="38878" checksum="DC4335C4BC8B184E" modified="2013-05-29" version="1">MTQPYRPDLSTPPPLPVRAWEVPLPPIHDEEGRFLVDHEKEELGLTIHGTEGEDRQQDMVESTDAATSPSSPKRERVYRTTLPVRPRDAEGGLQLEPPVIKEDSEDTDSDSETVTGHESDSDAEYAIADDDFEPASPRARRHLASHNGPGGWYHAPTTRRVTPTAPFIINPVARSSPSGVSSTPTPDSTKKLTSTPSEWCIRPAAVEPSGSENTLPSVQWLRTGVPEPGAYLSADPPSYTNPSNASSTAKPASAPGPKPDTPIARMIQAHAQARLRSDSTSAGSSSPAGPRPSPRVQITSRLLRRRNPLGQPGPPDPAPVTVSSGEESDIPTSILFDRPVDWDQGKAPGTPKREARRRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8D1</accession>
    <name>M5G8D1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase signature enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_87616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631304.1">
        <property type="nucleotide sequence ID" value="XM_040776821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8D1"/>
    <dbReference type="STRING" id="1858805.M5G8D1"/>
    <dbReference type="GeneID" id="63691883"/>
    <dbReference type="HOGENOM" id="CLU_009600_14_1_1"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF34">
        <property type="entry name" value="OS04G0183300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067535" evidence="1">
        <location>
            <begin position="19"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="550" mass="58895" checksum="C253533353DA44B5" modified="2013-05-29" version="1">MRILPILSLLLGATATLAAQPKRHIPRHCVLPDLYDASVKELSNGMEAGCFTAVDLVKAYLARIGEVNEELHAVIETNPDALEIAAQLDKDRAAGIIWGPLHGIPVLVKDNIGTADKMNTTAGSYALLGSIVPRDAHVVKKLRAAGAIILGKANLSEWAYYRGSGISNGWSARGGQTSNPYYPKGDTWGSSSGSAVAAAVGLAAVTLGSDTGGSVICPSDRQNVFGIRPTLGWVSRAGVVPLSEHQDTVGPITRWAADSALVLEIISGPDYRDNYTLAQPDVVPRYTYYLDEHALEGKRICVPRQVFNQDNVTHNDPSIGVAFNKSLLEIAGLGATIVDPADMPSVLSGLYPANVSTGLVFATDFKVDIKNYLSELLDIPTGVHDLSDLIEFNIAHADLELPQLQNNQASWLTANATNGQDNSTYLADVWLDYYIGRTAGIHATLDKYGCDAIVLPSEGRTTTIATIAGCPIINVPLSYYPDTVNATAIHNGTQFFPAPGIPFGLSFLGRQWEDAGLLGLAYAYEQGTKHRLENKAYKKATPKTQLADVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Q6</accession>
    <name>M5G8Q6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_43334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631459.1">
        <property type="nucleotide sequence ID" value="XM_040774536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Q6"/>
    <dbReference type="GeneID" id="63689598"/>
    <dbReference type="HOGENOM" id="CLU_001305_5_0_1"/>
    <dbReference type="OMA" id="VINMSAH"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="103"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="390" mass="43711" checksum="EDB480E72F425BB4" modified="2013-05-29" version="1" fragment="single">LAERWEDLIEQVRQFKGFETFLEAPRCRSLHQAARDGPIVVINVSEYRTDALIVTGPGQIRCIPLKGLSDKVISGLAYTWHQALKCTKDREGSIYMNRVLQSISRRLWDGGFSQIAAALQEIRDSRHSRSAFRVWLMPTGMLSLLPIHCAGPCQSDQLGMYDFVTSYTGTLSCLILSRSGGGCTSSSAGDGTRHRLLAVAQPKVDNFPVLQGAEREIDALLDSPFSENMTYLSEAEATVSRFAEELPQHEWLHCCSHATWNSTNPLDSAFCLKDGKLTLSCIVRLRMWNAQFAFLSACHTARQTSLLPDESMHLTAGMQVSGFRSLVATQWAMADQDGPVLTRMFYDYLMKDGRAPDVRNTAESLHLALRQFRLRNIPMYRWALFVHAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9E3</accession>
    <name>M5G9E3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MOP flippase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_79302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629376.1">
        <property type="nucleotide sequence ID" value="XM_040776390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9E3"/>
    <dbReference type="STRING" id="1858805.M5G9E3"/>
    <dbReference type="GeneID" id="63691452"/>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OMA" id="EFWILLK"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="442" mass="47497" checksum="F00E74CDA52526DB" modified="2013-05-29" version="1">MQTAAVLIVGRLGPAELSAAAFAMMLAMVTGWCVALGGTTALDTLGSQSFTGSKDPSDLSIHLQRCVLLLYLLLIPVLLLWYFVQPVLLFLGQEVKLSSDVQAFLRVLIAGAPGYIGFESVKKYLQCQGIMHASTVVLLIISPVNVALNIYLVHYTSLGFLGSPLAVSFTYWLTFFGLVLFCMFSRAHRNNCAWAGFQPRRVLQLHPSWEFLQLALPGILMVGTEWWAFEIVAIAAGMLGARPLAAQSVIMTTDQVLNTVPFGIGVAASTRIGNLIGSRSASGARQASHAMAFLSVVLGGIIMIAMLATRNVFGYLFSDDEEVVNLVSSILPLVASFQIADGLAASCGGILRGQGRQHLGALFNLVSYYVLALPLGLTLAFAFGQGLQGLWVGQVIALFLVGFSEYGVVWLGSDWDKEIEKGIERLKGEEVRRSGLALSSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9E8</accession>
    <name>M5G9E8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632313.1">
        <property type="nucleotide sequence ID" value="XM_040777511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9E8"/>
    <dbReference type="GeneID" id="63692573"/>
    <dbReference type="HOGENOM" id="CLU_1981535_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="13425" checksum="46CCF798673E05E9" modified="2013-05-29" version="1">MSTSAKRRAEEEEEVPVIHEEDAPVPSAGGTAPAQGGPRKRGRPPGSKNKKTLAAEAAAAAAARVELAAEPSSPESSKRLTRSFEPGGPFTEESTAESPRKRGRPTKKTKVETTEEEIEETTKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9G4</accession>
    <name>M5G9G4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627335.1">
        <property type="nucleotide sequence ID" value="XM_040773202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9G4"/>
    <dbReference type="STRING" id="1858805.M5G9G4"/>
    <dbReference type="GeneID" id="63688264"/>
    <dbReference type="HOGENOM" id="CLU_1120152_0_0_1"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27170" checksum="78AA3C96C8BBB5D3" modified="2013-05-29" version="1">MRIALHDITLSKWAFPLPESVRTWTDEEVYRVLGSPDVAPVSTVDGSEPGPHAPAEVVAPADMSGLAKALKESIVCIDVGDAVQLDEGPLQRHPTPGLDIWSFAFLIFNILSGYPLIEPFWANEQGVLRQMEILLAKPPGSFRSRLIDHDAILSAEAARNTQNWAKLERHLRGVGTRDESRASMYVDAGRLPILARLDTRLTEEDVQTWKTLLSKMLAYMPDERPDIDMVCAWLEKPGEITMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9X3</accession>
    <name>M5G9X3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DnaJ-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_20055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632513.1">
        <property type="nucleotide sequence ID" value="XM_040771775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9X3"/>
    <dbReference type="STRING" id="1858805.M5G9X3"/>
    <dbReference type="GeneID" id="63686837"/>
    <dbReference type="HOGENOM" id="CLU_017633_10_0_1"/>
    <dbReference type="OMA" id="RVCPTCV"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000041">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="132"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="44088" checksum="63C81EADB08A38C0" modified="2013-05-29" version="1">MVKETKLYDLLGVSPDASESELKKAYRQKALRAHPDKGGDPEIFKDLTQAYEVLSDPQKRGIYDRFGEAGLSESGGAGGVDAQDLFSQLFGGGGGPFGGGGFFGGGGRPSGPRKGKDLVHRIHVSLEELYKGKTSKLSLNKHIICPKCNGKGGKEGAVKTCPGCRGQGIKIVIRQLGPMMQQIQQQCPDCDGTGEIINPKDRCKQCNGKKTISEKKVLEVHIDKGMKGGETINFAGESDQAPDMIPGDVVIVIEEKKHDRFTRKGNDLVIEIEIDLLTALGGGQFAIPHLDERALMVTIVPGEVIKDGAVKVIHGQGMPSRRHHDFGDLYVRMKVKFPESIDPAVIPLLEKALPARKATEKFPKNIHLEEVVLAEPDARQQRAANDEMEVDEDEDGAGPRVQCQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC9</accession>
    <name>M5GAC9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS Git1p-related glycerophosphoinositol permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_80284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627755.1">
        <property type="nucleotide sequence ID" value="XM_040776436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC9"/>
    <dbReference type="STRING" id="1858805.M5GAC9"/>
    <dbReference type="GeneID" id="63691498"/>
    <dbReference type="HOGENOM" id="CLU_001265_46_12_1"/>
    <dbReference type="OMA" id="RGPIFIL"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="49"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="501" mass="53422" checksum="0BE79C8DDF8D71D8" modified="2013-05-29" version="1">MNGEKDLDRAFDDKLDDEKGGLPGDVAAPTFQEDSQAKSPRDRTSSLFTIIAAGAGLISDGYQNSLMTMTNVILGLIYPTSYTSVVSTRVSNALLVGEILGQIFFGIMTDRIGRKTAIVTTTLFIALGSLIGTAANGANGSVDGLFWCLTFARGITGVGVGGEYPAGSVSASEAANERVLKHRGPVFIMVTNFVLSFGGPLAVSVFLIVLSAAGENHLGTVWRVCFGIGILLPLTVLIFRLKMINSRLYRAGAIKKRVPYGLVFKKYWRRLIGTCGAWFLYDFVTFPNGIFSGTIISSVVPNKDIKSTAEWQLLLGTIALPGVFVGAFLCDRIGRRNTMMLGFSGYLVFGLIIGCAYDRITQIVPLFIVFYGLMNSFGNLGPGDMLGLISSESYATAVRGTCYGISAALGKTGAAVGTQAFTPIQNNLGKKWIFIIAAICGVTGIIVTYTFVPKLTGDDLAREDIEFAEFLAANGWEGEIGEDDGEHLIGGTTTKAVPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB27</accession>
    <name>M5GB27_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628055.1">
        <property type="nucleotide sequence ID" value="XM_040768660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB27"/>
    <dbReference type="STRING" id="1858805.M5GB27"/>
    <dbReference type="GeneID" id="63683722"/>
    <dbReference type="HOGENOM" id="CLU_1199785_0_0_1"/>
    <dbReference type="OrthoDB" id="3425354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="26636" checksum="1DC2462C8C26B0B3" modified="2013-05-29" version="1">MSRPKPTHRIFLLTELVHEIASNLHSNADKFHFAITSRAMWFLLCKSLWHTVNNEALCCILPEDLLSVRPKHRKILLRQLSADEQVRFRGYSSHIRDLRITDAFLSIRRTLKAQYWLPVLRFFDSTHIVFPKLRSLYLVFSHSTAFPMECMPLLELVDLQELAVHCCPRPDHISRALSVILALLKNIKNTTNIRMFSFSFLALLLLKAATPSLTRSLIALADGYPGCEYCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB64</accession>
    <name>M5GB64_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_116977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628085.1">
        <property type="nucleotide sequence ID" value="XM_040770294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB64"/>
    <dbReference type="STRING" id="1858805.M5GB64"/>
    <dbReference type="GeneID" id="63685356"/>
    <dbReference type="HOGENOM" id="CLU_007183_0_0_1"/>
    <dbReference type="OMA" id="EWRSEAY"/>
    <dbReference type="OrthoDB" id="19394at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="15"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="697"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="845" mass="95143" checksum="CBEDCF0E61F9B567" modified="2013-05-29" version="1">MSLPIALKDISDKPQAGAVTDPVHPAQMQADIDRKLRLYGVVQAFRNGRMPTNVQINDALSYVEAHSPLDMSQLSAEGRNLIDDVRDIIETARKIVMEKNADELFQNFVWHTTYIDPNRGKVVDSLGDAVPVSQEQAKADAQQAVVHVRTLLSLFLTNAEARKLLSDVGLIGRDMFATGAANVAEKVRPDPEAMARVDDAAPSNQWKGADGRVHGPNETPVLQATLPGGRTVQAHPKEPLSNATYRDADGQERPTAEIAQQAQERVPVDDVTDREQWANAATNGARRNAEPHVRDVQGAVQRQPDDDGDAQVEAGKRTWKEKFNDFKANLNDRVPDEHKDKIREHRDAIKDHFKEQFPEERRDQFIWRMKKVVVENQKHGDYQETMNWFLNFLETYHGHAKSAVGTGSQSANALTEDPSLQLAWSEFRTLLERFANNRTMQPIIDAVNDLYNDAQQDEGLRHYFSRLDGFVRRTLLEPGYVLAPEYDDDARRVRDEGKQFFDEKYAPHKDRLFDSIQDFFLAMGDDPLNKQFGDDWARLTHDLLFDENGQLAFKPHLWGDIRRVILPSIVDQVGYVPIPRIEYTDDQMDLVIENLTLQGRNLLPNVIELEVHNWIKFSPYSTVTDDHHHSFRGIFGQIQADLRDVAFYFKKKQGFPKLSDSGVADVVIGGSGISGTVHVASAGKDKSSVFTVKDVHVKIDSLNFSIRDSKHDTLYKVLKPLATGLIKKQIAKALQDAIRTGLEYVDGELVGVRDRMGEAKAQDGVTRTDVPKQAFQRKKAEAQSVKEKTGEFKIDTTRDSMLLPNVGHEGGLINRQFERAEAAKRGKEWRSDAFSIVPQGSANRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBP6</accession>
    <name>M5GBP6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial inner membrane protease subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_73849</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S26 family. IMP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633298.1">
        <property type="nucleotide sequence ID" value="XM_040776031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBP6"/>
    <dbReference type="STRING" id="1858805.M5GBP6"/>
    <dbReference type="GeneID" id="63691093"/>
    <dbReference type="HOGENOM" id="CLU_028723_4_1_1"/>
    <dbReference type="OMA" id="RITHVEW"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.109.10:FF:000005">
        <property type="entry name" value="Mitochondrial inner membrane protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="13">
        <location>
            <begin position="28"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU06404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="233" mass="26970" checksum="0636FAA07EFFBAB4" modified="2013-05-29" version="1">MSFYYSFLRSRFRLRPIIDTLAWVPFGIMFTQVGYSVINIKGNSMQPTFNPESSLRKDMVLLNRFVAWWDVTQLKRGDVITLRDPTNPDLLITKRILALEGDLVRTLPPYPDTYVRIPPSHAWVEGDEPFRSSDSNHFGPVSLSLVDARVEAILWPLDRMRVLHGAWQAAAEEREGKRGDELERLIAEVGKRPGRQYAIFWKEMERARGRMQRVYVHGGMEGVGKQVLRQGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC33</accession>
    <name>M5GC33_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_19367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632934.1">
        <property type="nucleotide sequence ID" value="XM_040771476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC33"/>
    <dbReference type="STRING" id="1858805.M5GC33"/>
    <dbReference type="GeneID" id="63686538"/>
    <dbReference type="HOGENOM" id="CLU_056222_1_0_1"/>
    <dbReference type="OMA" id="CQIASAH"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="6">
        <location>
            <begin position="238"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="308" mass="35218" checksum="A31A50FA666B7A1E" modified="2013-05-29" version="1">MPFVKTVKSNAYFSRYQVKYRRRREGKTDYYARKRLIAQAKNKYNAPKYRLVVRFTNKNIIVQIAYARLQGDFILCAAQSRELPKFGIEHGLTNWTAAYATGLLCARRALTKLGLADKYEGQVEPTGELALVEGLDDEDAPRPFKCYLDAGLKRTSTGSRIFGAMKGAADGGLFIPHSEKRFPGYDVESKSLDAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFSSYLADDIGSDDLEEIYQNAYSAIRENPTFEPTEKETDWKAESLKYKVHRLTQEQRAERVQEKIKMFQAGRAAAGEAEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC51</accession>
    <name>M5GC51_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_103549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDUFAF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633498.1">
        <property type="nucleotide sequence ID" value="XM_040767776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC51"/>
    <dbReference type="STRING" id="1858805.M5GC51"/>
    <dbReference type="GeneID" id="63682838"/>
    <dbReference type="HOGENOM" id="CLU_074390_1_2_1"/>
    <dbReference type="OMA" id="VMDTWNA"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05125">
        <property type="entry name" value="Mth938_2P1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034095">
        <property type="entry name" value="NDUF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="183" mass="20105" checksum="012F132B8CC0753E" modified="2013-05-29" version="1">MFPRTLPHLVQNARPLSRPILPNILRSTSSTAHLIRRQSTLENILAPPLAALSVAQITSSGVELSDGLVLRGPAILLNGRAFLWDPPPAGGSWKGWGKETWGLLEVVVPRPEILLFGTGRSLILPPPSVRTYLNEMGIQVDFMDTRNACSTYNLLLEEGRRVAAALLPLNKHVPWLTIPRDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCC5</accession>
    <name>M5GCC5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_97727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633044.1">
        <property type="nucleotide sequence ID" value="XM_040777477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCC5"/>
    <dbReference type="STRING" id="1858805.M5GCC5"/>
    <dbReference type="GeneID" id="63692539"/>
    <dbReference type="HOGENOM" id="CLU_936964_0_0_1"/>
    <dbReference type="OMA" id="GMIEANI"/>
    <dbReference type="OrthoDB" id="5289249at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="116"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="31751" checksum="8CA5AC9582EDAAC0" modified="2013-05-29" version="1">MIVTEEKKLPLAPDTPLAPQGANNPFTPAAASSSEAPQDGAPPPYEHSESAFTGTISTASSSAAPGSSTVAPGTPVADRDSRLDMLSGDPDDYSTGPSVLPPHHEDPIPPGLPKQNKLRVHKDNHSIKDVFVIDANLPAPPGSPERALDLFSSNGSVYAKVYLIGYDLKRRVELAAKSKNGSVKFLIAECPRTMPISVNCESHNGSVTVLLPPKFTGPLQISHKNGSVTLFPSLKARTRTLDESSTTRRCWVGEWPGETEWDGDECIVGSLNGSVRIGFWEGEPLEKPAGFFKRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCG7</accession>
    <name>M5GCG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">DACRYDRAFT_94067</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630771.1">
        <property type="nucleotide sequence ID" value="XM_040777195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCG7"/>
    <dbReference type="STRING" id="1858805.M5GCG7"/>
    <dbReference type="GeneID" id="63692257"/>
    <dbReference type="HOGENOM" id="CLU_009279_1_0_1"/>
    <dbReference type="OMA" id="TWYAIGT"/>
    <dbReference type="OrthoDB" id="10261066at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
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        <location>
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    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="22">
        <location>
            <begin position="21"/>
            <end position="420"/>
        </location>
    </feature>
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            <begin position="565"/>
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    </feature>
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        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="20">
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            <begin position="756"/>
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        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
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            <dbReference type="ARBA" id="ARBA00012605"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00059243"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00067960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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            <dbReference type="Pfam" id="PF02516"/>
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            <dbReference type="Pfam" id="PF21436"/>
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    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="772" mass="85713" checksum="9FE846FAD0843581" modified="2013-05-29" version="1">MTILKLPTFAPSTLTNAASLIRILALAFIAGAAISSRLFAVINFESIIHEFDPWFNYRATRVLASQGFTEFWNWFDPTAWYPLGRVVGGTIYPGLMATSGVIYNILHALHLPVDIRNVCVLLAPGFSGLTAWATYMLTKELKDESAGLLAAIFIGIAPGYISRSVAGSYDNEAIAIFLLMITFYIWIRALKDGSVLYGTLAAVFYFYMVAAWGGYAFITNMIPLHAFVLLLMGRFSHRLYSAYSAWYAVGTLASMQVPFVGFQPVLTSEHMAALGVFGLLQLVAFVETIRNLLASKQFQLMLRWFLIAAGVAGGLIIVGLTVTKTIAPWTGRFYSLWDTGYAKKYIPIIASVSEHQPTAWPAFFMDLHMLIFLFPAGVVLCFKELREEHVFVIIYSVMASYFAGVMVRLMLTLTPVVCMTAAIALSSLLDTYLNVDEPANPDANGVKETATSGAETPVDGTISKKKKKGVAAAAAAAAVTPSIATKAKGRSSAENGIFGIDTRILVIGNAIFMLVMFVLHCTWVTSTAYSSPSVVLASRRPDGSQNIIDDFREAYYWLRQNTPQDSVVMSWWDYGYQIAGMADRPTLVDNNTWNNTHIATVGKAMSSPEEISYPILRKHDVDYILVIFGGLIGYSGDDVNKFLWMVRIAQGVWPDEIKESNYFTPRGEYKVDDQASEAMKNSLMYKMSYYRFNDLFSGAPAFDRVRNQQMPKEGPKLDYIEEAFTSENWIVRIYKVKKEDPLGRDLKTAHAFDGGKRRKPSKPISRRKALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCL6</accession>
    <name>M5GCL6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_21325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772341.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="445556at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051938">
        <property type="entry name" value="Apopto_cytoskel_mod"/>
    </dbReference>
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        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145:SF3">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="26214" checksum="777EDEEA7565A1A2" modified="2013-05-29" version="1">MLRATVCCRSSANAFRSFSTSLVTRAATLDLSYPSHGHPTPYEIFHLPRTATQDEIKERYYELVRLHHPDSPVCRHEPDNVRQERFKAIAKAYEILKSNRNPAYLKELHRRQTQHGYPNYNPTRRQQYAYHSLEEGSMDVGNGDVFFVVTILAILGSVVLIYSPFSAKERLDAHHASASHALAEARREAKELSVHRRKNLRKWIEEAGLEGVTPNVGHGSARRQTPSSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCP7</accession>
    <name>M5GCP7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_105063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630886.1">
        <property type="nucleotide sequence ID" value="XM_040768028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCP7"/>
    <dbReference type="STRING" id="1858805.M5GCP7"/>
    <dbReference type="GeneID" id="63683090"/>
    <dbReference type="HOGENOM" id="CLU_025750_0_0_1"/>
    <dbReference type="OMA" id="LFEWSLH"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="3">
        <location>
            <begin position="205"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="615" mass="66588" checksum="21C1A3A19887B1A9" modified="2013-05-29" version="1">MALGKRSRTLPTLSNNKLPSLTVPHPKRARTSLSPLTDCDPYSNKENIPPSPCPSSPIPSVVSLHDELDMDTRVTRSRARSSTPRIERLPSTRRMPRRADPAPEKTSTRRTTRLTIPVLAPTPPLTPESEGDSFDAPLLTPSLDMGRLILGDEDIKCPSPTSNAYVTARGALKAPPSDLAGREDQRIELLAFLSPFLSGLNEDDDSRVMYISGTPGTGKTALVKKMLSEIKADGVRTGMINCMGLASAKEVWDTAWGTMEAEKVKDSKMSLEKLLEEGDKFVLVLDEIDTLLRLPSVLSTILNLPSQHPNLCLLTIANSLSLPSQLPASISLTQVSFAPYTWEQMTAIVKCKLPSECTVIDEKALELAARRVGGRTGDLRVLVEVLRKALDAAEKDWKKRTAENPFIACDLVKVSPAHILAAIKTVTFPSSSTASSAPSASSPTTVLIRTLPVQTRLILLALLVASYRTSLGLPLTSVPSFGTAAKSKSTAPTPTQLFASYSALLSKYGGTLPPALGSSDFHDVLNMLEASSLVSYASSTGPKKRTTALRCVTLVPQEEEVRRAMFLGLDQSAEGVEEALKSAWTKVCKDARNEVVRRGKKAEREANECPLEERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK6</accession>
    <name>M5GDK6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_98499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631496.1">
        <property type="nucleotide sequence ID" value="XM_040777531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK6"/>
    <dbReference type="STRING" id="1858805.M5GDK6"/>
    <dbReference type="GeneID" id="63692593"/>
    <dbReference type="HOGENOM" id="CLU_003041_18_1_1"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="292"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="643"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="131"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU04602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="813" mass="90814" checksum="4E9AAC21DAE78EE9" modified="2013-05-29" version="1">MNRTVRLAREAGGGQTRYKGRPLRGQNSPEGSTSRAPRGSRTPPSSSRFPRKSDSSRSDRRPESRLSPHSGSTPSGSDRNLSRLPRRTSEGSDRNLSRFPRRTPESDDKFRRVYEKNMYSRTKVGHSRVYVNREVKDKMYGRTTKAREVESDTQERRSRKWEEGGSRERARGREIDSGNLERRSGRRDVGASRERGDHSRGREATMDTQERRLGSKEEYRERRERRRNREDEDAALPTAGPADTKVRPFTAYSPPLSPGLLQSVTELLGTNPPSPIQTLSLNYFFPQNRKSNPRTKKSSETLLGAETGSGKTLAYLLPVLQSLKETEQTEDKGDGKQRFNSPRALILAPTHELCRQLAASVKQLTHIDKLRTVCFSNPIPKGRKRATANDESLYDEDVTPEDYEAQHGFLRPADVVVGTPSKMLEMFRLSDSVEEKLDEQGEVVIKADYGESKGLDRVQWVVVDEADVSFGKNFRPATRALLHFVREARLKALGRSKAPDKEPVPQDEITTPEVQVIEAESAEKEYTNVTPTVTDVPPPVSTEDTSAAPAEKPTTTTKVDPTKAFTAPPFNLVLSTATVSSSLGTQLAVYHPRMIQLLSPNLHKLPATLRTEHVSWSGGNRTADVAAKIFSIWTQEARAMRLETGKRYTSMDRSKILIFCNTASHAEKLGRELGEKSISTFVLTSESTLRRHGSNKHLEGFLKVADKAGDQGKIEAQAKQTWKEQDLEDKQPVVPTAVLITTSLLSRGLDFAPSVKNVLIMDEPQNMVDFVHRAGRTGRAGAEGKVILFGKGGKRSESSYLQELRTRAKTLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDX6</accession>
    <name>M5GDX6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631806.1">
        <property type="nucleotide sequence ID" value="XM_040777542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDX6"/>
    <dbReference type="GeneID" id="63692604"/>
    <dbReference type="HOGENOM" id="CLU_639385_0_0_1"/>
    <dbReference type="OrthoDB" id="10474801at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="429" mass="49029" checksum="BD712A4D6CD7F853" modified="2013-05-29" version="1">MVDAYARAGLDAPHLARRVAFFHAMEILTATIPLDGGLVPWFVVLTEEPRTSEASFMLNKIFGNIILELIESGFSERKDATIISILDAFERHDGRARCQNSAADLFLRIAETHLESLDEWSSYISLASFRYMARMMDSWDLGYLLDNLALNGLEQDIVQHPTFTGTVTKLIYDIMRRHLQKERLAWRCPDSELNMIYNSIFNLYPIALRVFTFHGSAFGNALLALCTYCGFCLKEMAIPLTDELVTMTRVLSTHEVNANEFLISRTDRNSAYRDSLRMWGFVIRWKGHRDWGVDTQELKQESRHDYKARKGREQGEQGEQGERLGQHAGAKNSYTILTEPDNSDNGPLAKRAKYDPAVQLEPSSDDLNLFSQGIEINEPRRTRPNGRDRLPSSDDMDLFQHLTPAIRRRRPRGLTSFKQRMLNAGADVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEE0</accession>
    <name>M5GEE0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RabGAP/TBC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_113490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632236.1">
        <property type="nucleotide sequence ID" value="XM_040769638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEE0"/>
    <dbReference type="STRING" id="1858805.M5GEE0"/>
    <dbReference type="GeneID" id="63684700"/>
    <dbReference type="HOGENOM" id="CLU_017119_0_0_1"/>
    <dbReference type="OMA" id="ELAQWIC"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000038">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000031">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="152"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="713" mass="79316" checksum="8DC447393757FF2B" modified="2013-05-29" version="1">MAQSYPQADQWARPLPHEILLAFNNLFRSGLTIATLREAIINGRVDRLSNRIELKALKASRPDGGRVGRSLLWKLFLLPGCPLLDGNPVNATLCISELRSARRAYSDLAAARLRAPDGRAIPSSSTHEDATVSMPPQSSTDAGGWEKNNPLSLDAENPWQQWFADLELRKVIRQDVERIFPEISYFSSQTVRENLTDILFIYCVTHPEIGYRQGMHEVAGTILLVVDNDSIDYGAGIKDDELQECCARKSVSADVYAVFMSLMEGAHRWYEWREPRRRDVRGQPESWTAPIVHVCRMIQDQMLRSVDPALWAHLDSAGVEPQIYGIRWLRLLFTREFPLSTAVAIWDCLLAADPSLELAEWVCVTMLLRIRNQLLSTDDYSTILTYLLHYPSLDQDMPWLLVKQAATIHENPVPTTGVTVMLQNRDILEIAIEAKSSGFREAAPTRPGEGMRTERPPEKAPLGLTDVIAKHLMERTDAVTLNRAFLSTVTELRKGLPDLTSTLSKTFMTQPVPLGSTPGSTSEDTLRSAQFVSLYTEQERLGHAVGWAISALKDNPSSLDALRCLETVQNVLLRKVPFDASRLEPGFWTKVPSQATVPPDALFCPTNPRTSLFPNKLSGGNTAPGVVGMNSRLPRVHDARIPVDRRVQSQPVVSPMPPMPPPSHGTVMTSPQVTEIPEAANGSQNECTVEPAKGGRTEEDRQNLLDPLGVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEF0</accession>
    <name>M5GEF0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">SWIRM-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_19898</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632271.1">
        <property type="nucleotide sequence ID" value="XM_040771710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEF0"/>
    <dbReference type="STRING" id="1858805.M5GEF0"/>
    <dbReference type="GeneID" id="63686772"/>
    <dbReference type="HOGENOM" id="CLU_004447_3_1_1"/>
    <dbReference type="OMA" id="QQFNEME"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02336">
        <property type="entry name" value="ZZ_RSC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041984">
        <property type="entry name" value="Rsc8/Ssr1/Ssr2_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIRM" evidence="13">
        <location>
            <begin position="145"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="12">
        <location>
            <begin position="337"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="14">
        <location>
            <begin position="394"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="11">
        <location>
            <begin position="399"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="503"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="639"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU05377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="721" mass="78314" checksum="A4249DCAD0512062" modified="2013-05-29" version="1">MSSPHPKRTASPAPGGDAKRLRVTLPNQPQGATQVDLSNAPGKKTEAEPIASTDISNLPNVADTYGEAGPSSQGIVANPSSEAEPADEADVAMTGGGEQENKDGDEDMDEGEEPQEEEDAAALEQTRQALEEQARQYLAAQTQEIIIPSYSAWFDMSKINPIERKTFPEFFNGKNKSKTPATYKEYRDFMINTFRLRPQEYLTFTACRRNLAGDVGAIWRIHAFLSQWGLINYQVDPETRPASLAPPFTGHYRVILDTPRGLQPLHPGSAPPKLNVAPAMPHTPAIGAPETPAKLASANFELRQSIYQTGVKGAKEVSATDAAELEKEISSGGAVNKPTYACDTCGVDCTRERYHSLKVPHFSLCPSCYLDGRFPSTMYSGDFVRITQSPFAHASGEEWTDEEVLLLLEGIEMHDDDWAAISEHVGTRTREQCVQKFLQLPIEDPYIEAEADVGPLKYSRIPFEKVDNPVMSVVAFLAANVSPPVAAEAAGAALGELTEGLRKSLKKPPKEGAEEGAEPAVTEKTPAPAEGEASEDHQMADAEQVTKEEERTPAPVQAANEEETIEVDKPAEESEAPAVNGTEQPKPGVPQSAVRRAADLALKAAAARASSLATHEDTVMQSLVTRVVKAQLTKLEIKMTGFEQLEELLESERRTLEEQRIGLERDRESLRKQAEKLGDRAKELGVDLEQLGGKTLAQELAAHVEEPMLPAGQSAPMLTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEK6</accession>
    <name>M5GEK6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_50152</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630237.1">
        <property type="nucleotide sequence ID" value="XM_040774974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEK6"/>
    <dbReference type="STRING" id="1858805.M5GEK6"/>
    <dbReference type="GeneID" id="63690036"/>
    <dbReference type="HOGENOM" id="CLU_085752_1_1_1"/>
    <dbReference type="OMA" id="MSVCPPY"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="24"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="94"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU03343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="166" mass="17027" checksum="64A3375447DFC9F9" modified="2013-05-29" version="1">MSKLCPPFAPFLGFAGVTSAVSRCASVGAAYGTSKAGIGITGLGTFKPELLMRSLIPVVMSGIIAVYGLVVSVLISAGLSPDTEYPLYAGFIHLAAGMSCGFTGMAAGYAIGIVGDACVRAYAYESRIFVTMVLILIFAEVLGLYGLIVALILNTRVSGLEGICSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEW2</accession>
    <name>M5GEW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630527.1">
        <property type="nucleotide sequence ID" value="XM_040769922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEW2"/>
    <dbReference type="STRING" id="1858805.M5GEW2"/>
    <dbReference type="GeneID" id="63684984"/>
    <dbReference type="HOGENOM" id="CLU_009210_1_0_1"/>
    <dbReference type="OMA" id="PFTRPHT"/>
    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="689"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="754" mass="85505" checksum="AE2683DE37ACE0FD" modified="2013-05-29" version="1">MSSLIEIVRKRFLDAIRSVNPAGRWKIVVVDEHSQKLLGATLKMFDILQENVTQVDAINSNRTLQPNLEAMYLVMPTTQNVERIINDFSSGKQQYAAAHLFFIEGLPEPLFQRLTASAAEPFLRQLVELSINFWPLEKQVLSLEHPDFFFSFFSPPPSQALFQAAYERFEDDLWFTSRCIVNACIQLEEFPLIRYHQPSTHGGLGPLKPPEPVVPESTSSSRWKGARQAQPQAEVVDDHISKRLAYMVQDALDEYRRTNPEFPKSANAPRPRGVLFITDRTMDLYAPLLHEFTYQAMAVDLLPIEDGTKYRYKFQSSIGASEDKIATLSDADQVWTQVRHMHMREAIDKLMEDFNKFLEEHAGFKEGSGATSLNDMKDMLASLPQYQEQRERFSTHLNIAQECMALFERKKLPLTANVEQCCATGLNTDGKSPKTLVEEMVPLLDDRYVSNRDKVRIIALYILYRDGVADEDRRRLFQHARLTMAEQDAVNSLVHLGARILRGANDGNRKRSKVKTSDDEQYELSRYRPVLKTVLEDHFANKLEMTFFPYVRDAPVTTIQASQLRSPANPTSAASLRSAKPNWARAQRAGAPVAEIRQRALVFIAGGMTYSEMRTVYEVSAALGKDIFIGSTHVFSPEQFVDDMKVIEIGGKGSAELPQGLQLQPSPPNHHRSYQASYDRRYWIRDAPAATRPSSSNLTPRSKARVLSSSSIPSREATPEPTALTPPPSSISSRLQKEKKEDRKDGKKKGFFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEX9</accession>
    <name>M5GEX9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">T-cell immunomodulatory protein TIP C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_75178</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632691.1">
        <property type="nucleotide sequence ID" value="XM_040776115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEX9"/>
    <dbReference type="GeneID" id="63691177"/>
    <dbReference type="HOGENOM" id="CLU_020272_1_0_1"/>
    <dbReference type="OMA" id="PGDWIPW"/>
    <dbReference type="OrthoDB" id="10022113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057089">
        <property type="entry name" value="C2_TIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024881">
        <property type="entry name" value="Tip"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412:SF0">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23122">
        <property type="entry name" value="C2_ITFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067793" description="T-cell immunomodulatory protein TIP C2 domain-containing protein" evidence="9">
        <location>
            <begin position="31"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="658"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="T-cell immunomodulatory protein TIP C2" evidence="10">
        <location>
            <begin position="549"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="704" mass="76525" checksum="75B77B5118E28C82" modified="2013-05-29" version="1">MQSWQRRGRRPTCLLLLCSLWLGILDEAAAVWPFPAKRFSGDMLIDAGSLGLAELDGRVVAFGDFNGDQYTDIVTLSTDQRTLTVYIWDHSRYLFTKTQSIPFSQNVVNVVAGDFSFDGRLDILVMMSQNTGSWGNQAIQVGMAVYLGQGNGMFSGSPVAVPGSAAEEPIVLDATGDIKVDLLGMFPTSSAPGPPTWRLWQNIWNTTANAGDMFELTSPPLNTSKVCKLSNPHSSAVIDLDGDCLADLFLVCDSPTSANRKTYQIWINNKEGGFTLSREGDLPPGVGPITFADMDRDGTIDLVFPTCQSVNTDTGVGTNCAINIAYNKQIPTCAGSTGVIYPHAVGSCRLPTQLCAADSNFSFDFTNSPDNDAFQSIPLTSLGASHSANLLMFDPTFHPPLPLPIRIADTSLSGYPSLLPIIATQTPGGVLGIGSSLETSVQLLNNVPCREGIPGCEGERIAKGRRAFAVATDGTQVLKAIHDVRGVTVIDLDEDGTLDLLIQRTGTQSTTKLTFVQNNFFHDAFFLKAITLNGACSGFCQRDGENYKPFGTGFPGASYKYTILDTTGKRSAAQGMFPTQHLGQQPQTGYHALHTPYAYLGLGRTNNYIENLFVGSTSHAEAHYINLEGVIPNSRLVVNPTVWKSNWEYELYLRPGDWIPWVTVVALASCGLLAIIVFVLHLNEKREDERERRRGLHHINFDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF37</accession>
    <name>M5GF37_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">RuvB-like helicase</fullName>
            <ecNumber evidence="16">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_112769</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="function">
        <text evidence="14">DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="16"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632836.1">
        <property type="nucleotide sequence ID" value="XM_040769507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF37"/>
    <dbReference type="STRING" id="1858805.M5GF37"/>
    <dbReference type="GeneID" id="63684569"/>
    <dbReference type="HOGENOM" id="CLU_028311_1_1_1"/>
    <dbReference type="OMA" id="RTLPYNK"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 16 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 16" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 16" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="75"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU05942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="481" mass="52125" checksum="2E5C5412901FAAAF" modified="2013-05-29" version="1">MKVTTLQPSQGPTHHSAAPAEQARQLRVASHSHIKGLGLSETGEALTQGSGFIGQAQAREACGVVVDLIRLRKFSGRALLLAGPPGTGKTALAMAISHELGTKVPFRILVASEVYSAEVKKTEVLAENFRRAIGIRVKETKEVFEGELTELTPTEAPNPLSGYGKTISHVVIGLKTVRGTKQLRLDPGVYEAIQKERIVVGDVVYIEANTGAVKRVGRSDAYATEFDLESETYVPLPKGDVHKRKELVQDLNLHDLDAANARPQGGQDIMSVMGQLVKGRRTEVTDKLRAEVNKVVKGYVDQGVAEIVPGVLFIDEVHMLDIECFSYLSRALESPMAPHVIFATNRGLTLVRGTDDITSPHGIPMDLLDRCLIVRTEPYRREEIRKVLEVRAGVEGLAVGTEALDKLADEGSRSSLRYALQLLSPSAILAQLSGRQEITPEDVQETHDLFLDAKRSARGLEDWASESESSGPGGGGAVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFL3</accession>
    <name>M5GFL3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19583</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633316.1">
        <property type="nucleotide sequence ID" value="XM_040771573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFL3"/>
    <dbReference type="STRING" id="1858805.M5GFL3"/>
    <dbReference type="GeneID" id="63686635"/>
    <dbReference type="HOGENOM" id="CLU_001882_2_3_1"/>
    <dbReference type="OMA" id="FAWRIMG"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00807">
        <property type="entry name" value="GlnRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000183">
        <property type="entry name" value="Glutaminyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1290">
        <property type="entry name" value="Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007639">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042558">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042559">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04558">
        <property type="entry name" value="tRNA_synt_1c_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="13">
        <location>
            <begin position="106"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="275"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="12">
        <location>
            <begin position="587"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="14">
        <location>
            <begin position="701"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="778"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU06422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="872" mass="96398" checksum="05C7FAF80149D390" modified="2013-05-29" version="1">MPPKFDPSDPAVVQLITLFDSLGLSPSKSLETAKSSKNAAQLKELIIAHGLEGKNLEEKKALLVAALAAQGTYLGSEAKAYVIDKVLEGKLERGDQLTAAVKYLAQHQLTATMNYLEPHRGAINEAEFDAECGVGVVVTPDQAEQLVLLYLAENASAIEGWQSFSATLMKLKATPELRWAATLDVKNATEAAFLNKFGPKVSVNPKDMRKAAASKTATPGNVTPTASDSSSGIVALSSEKTVFEEGFLGRLHKPGGNPQLNGALREKHLKTTGGQVWTRFPPEPNGYLHIGHSKAIFVNFGYAAHFGGKCYLRYDDTNPEAEEQQYFDYILEMVRWLGYEPWKITYSSDYFQRLYDLAVDLTRRDKAYVCHCSAEKIFADRGGEERGPRKACEHRNRPIAESLAEFEGMRDGKYKPGEAILRMKMDLEDGNPTMWDTIAYRVLNAPHHRTGTTWRIYPTYDFTHCLCDSFENISHSLCTTEFILSRQSYEWLCDALEVYKPKQSEYGRLNIQGTVMSKRKILKLVKEGHVSGWDDPRLYTLIALRRRGIPPGAIISFVSGLGVSTSPSNIQTVRFEQAIRQYLENSAPRLMMVLKPLKVTLENVPEDYVLMIEKPLHQKVPELGTSSVPFTRTLYIDAEDFRLEDSKDYFRLAPGKTVGLFQAPAPVTCTRYSIDPVTGEVAELFCTLGESNSTSNKPKTFIQWVADHPASGSPIRVDETRIFHQLFKSDDPAATEDFIADVNPNSLEVVEGAFIEVGFWPLAKKAIGDARKDSEARLKAAATSGSEPAKEASPVGALHDAHNQPVASVEQLVGNECVRFQGLRVGYFAVDKDAQLGCLTEGDAPKPGSRPGDVVILNRIVTLKEDSAKKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGH4</accession>
    <name>M5GGH4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_46247</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632387.1">
        <property type="nucleotide sequence ID" value="XM_040774691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGH4"/>
    <dbReference type="STRING" id="1858805.M5GGH4"/>
    <dbReference type="GeneID" id="63689753"/>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OMA" id="FCDARED"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="270" mass="28960" checksum="967C26EB763A843C" modified="2013-05-29" version="1">MGDAPTDKEYEYILTSKPDPNVTLITLNRPKALNALSNGLFHELNHALARAELDNDVGAVVLTGSEKAFAAGADIKEMKDKEFADVYGQNFLSHWTQITEMKKPVIAAVSGYALGGGCELAMMCDIILASPTAKFGQPEINLGIIPGAGGTQRLTRAVGKSKAMEIVLTGRNITAQEAEAWGLVSKVVGEGEGQVVKEALEMAKTIASKGRLSVMAAKEGVNAAYELSLHEGLHFERRLFQSLFATKDQKEGTTGMGAFAEKRKAQFTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGM9</accession>
    <name>M5GGM9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH-ubiquinone oxidoreductase 24 kDa subunit mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_75147</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
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                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
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                <person name="Salamov A."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
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        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
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        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
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        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
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    </dbReference>
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    </dbReference>
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    <feature type="binding site" evidence="9">
        <location>
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        <source>
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</entry>
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                <person name="Benoit I."/>
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            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
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                <person name="Wiebenga A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="51" mass="5433" checksum="35EB7FC11E8CB4D9" modified="2013-05-29" version="1">MGTGGKAGLREPVPRLEESDEEDNNVADLDVKAAWSSLPLVGRVIPELVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNT5</accession>
    <name>M5FNT5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624803.1">
        <property type="nucleotide sequence ID" value="XM_040773875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNT5"/>
    <dbReference type="GeneID" id="63688937"/>
    <dbReference type="HOGENOM" id="CLU_2558246_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="82" mass="9009" checksum="3E7A8DD5003128B0" modified="2013-05-29" version="1">MNWPNGWILTQLSDCKDVEKQIYANSYVRDYAPRSSVSSGNAAVAHSTLLPTCRQGGGRIKDGRNGLIRGWLDVSRKLQSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNU0</accession>
    <name>M5FNU0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_25642</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623456.1">
        <property type="nucleotide sequence ID" value="XM_040774252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNU0"/>
    <dbReference type="STRING" id="1858805.M5FNU0"/>
    <dbReference type="GeneID" id="63689314"/>
    <dbReference type="HOGENOM" id="CLU_021802_2_3_1"/>
    <dbReference type="OMA" id="WMHGRGA"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF32">
        <property type="entry name" value="ARGE_DAPE-RELATED DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="8">
        <location>
            <begin position="218"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT96558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="439" mass="47956" checksum="E1FAD1EF8A9CD665" modified="2013-05-29" version="1">MTTLTPGQRARIKDATYRLLQPCTVFLQQLVRIDTTNPPGWNYPECARLIGDTLSSLGYDVDYYEVPECDLPRLAPHGKGLPRVNVIGRHEFAAGQGKVLHFNGHYDVVPCSEPAAWASQPFEAAIRRSADGKEEIVGRGVSDMKGGIAAQVFAIEALKLAGLRLKGTVEHSGVVDEETTGINNAGMGYLVDIGVISPKKQSAIVITEPLNTTNVCLGHRGAIWGRIIFKGVETHGSTPQRGKNALAMAARYIVAAEEEIGASLKNKVDTRVVPPEAQTASLTFTIFNSGHATNLVPAVATLTFDRRLVPGETLDLARGEMQSLLRKLFHDDEWIYEETYSTEPVWVGEEEEIVQVWKRAVHDACNVTAGIVCSPGSDDQRFVVHDARLNSCIVYGPGNIRNVHNLNESLPLEDLRTGMEVMALGAAMYLGFEDIQIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPD0</accession>
    <name>M5FPD0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_119781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623881.1">
        <property type="nucleotide sequence ID" value="XM_040770863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPD0"/>
    <dbReference type="STRING" id="1858805.M5FPD0"/>
    <dbReference type="GeneID" id="63685925"/>
    <dbReference type="HOGENOM" id="CLU_022453_6_0_1"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="11">
        <location>
            <begin position="121"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT96983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="384" mass="42375" checksum="6FD0999864CEE382" modified="2013-05-29" version="1">MSLSADKPNKPAVSSNWEALKKSIGANNGPRGIKRKRGGFHERTSNTIQNVPNKTATSGENEEIESFPRGNTYAEVVRSTAKASAHTVTEPVTKRPKTVTDEMRSLVLGTLSKSQEAEQGKYVALDCEMVGVGPNGSQSSLARVSVVNYHGAVLLDKFVRQMERVTDYRTRWSGIRPKDLQGAEEFKVVQAEVAKLMDDRIVVGHALSHDMQALLLSHPHHHTRDTQTYAELRKLAKTKQPALRKLIQLELGLDIQAGEHDSITDARASMALFRLHKNAWDRTLPASHHLLAKDGKGRPGKGKTESDNVGGRKGISSGLSVVTRVKEKNGVVSTRMSGKGRKHVEEEDGGSVRTRTESAWWETLTEDGKQHNMKGRKASLRMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPL7</accession>
    <name>M5FPL7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24256</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625548.1">
        <property type="nucleotide sequence ID" value="XM_040773612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPL7"/>
    <dbReference type="STRING" id="1858805.M5FPL7"/>
    <dbReference type="GeneID" id="63688674"/>
    <dbReference type="HOGENOM" id="CLU_001570_25_0_1"/>
    <dbReference type="OMA" id="DETIEEW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="512" mass="58301" checksum="8676C238FEE9D2C4" modified="2013-05-29" version="1">MLVLIIERILAYQRSVAIVREIPGERYPFSSMSIPGAMLPSSCWNPGRLVRWNKRRTLYDKNPNAEIVSELGYIGGYPVLISKSPEVAKQLLGFKTDFDKEEMIMNTLAPFGPNVFATNFHDWPRHRRVVQPGFTTSLYHAVWTETVNTYYDCMTTEKWEKEKSFIMPDVPAITSKLALFLIAKCGFGIHLAWNEQVGHKVNGMSLPDCFNTTSTAVVLLAMLPQWLFGLPLTSLRRLNTARQSLEVILQDLIYKRRTEGVENIDENANKDIFSLLLKANDDEKGSRAYLTDRELVSNVFLLLLAGYETTSRSLAATLALLACHPEEQEKAYQQIKSVVGSVRDPPYEDYERLPLVQGCFLEGLRMFPSAPGMIRIAVRDTILSVPTYDGKTRTVPIKAGQFIWSDWIGIGYNERVYSSAYTFLPARWLDPETEPLINFSYGPRVCLGKKFAITEAVGVLTLLLRDYRIELALKQGQTSKQWREKWEREGQESKIGFGPKRFPLKFTRRAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPQ4</accession>
    <name>M5FPQ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624136.1">
        <property type="nucleotide sequence ID" value="XM_040774117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPQ4"/>
    <dbReference type="GeneID" id="63689179"/>
    <dbReference type="HOGENOM" id="CLU_1219664_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067112" evidence="1">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="240" mass="26683" checksum="8C94C0F4C586D878" modified="2013-05-29" version="1">MQTHCVVLITLFATSVIALPLATYMDVSLTEEGSLWGRATVKEADEAAHAAWTEHARTEANRVQQQVRNMILEEYPHGLPQNANEEEWRKLHHFWDIHTNTLANNVEWQHLNHPDRKSPELGDYQNDLQKHKANTAALQAAEERLVQTTARHATTEIPSTAVAQAVATAKAQFVEASAQHSRTRALVSYHQTTPGKLLMPVPTEALAQRSSTSTKAPVNPHQGVWLVGRQAPRAHPPPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ16</accession>
    <name>M5FQ16_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_56797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625813.1">
        <property type="nucleotide sequence ID" value="XM_040775396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ16"/>
    <dbReference type="STRING" id="1858805.M5FQ16"/>
    <dbReference type="GeneID" id="63690458"/>
    <dbReference type="HOGENOM" id="CLU_2096795_0_0_1"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF12">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13157" checksum="B36280AF43186742" modified="2013-05-29" version="1">MLHNPEVVRAAQVQLDTVCGARLPTWEVRVKLRCIEALMKETIRWTWCASGHLERGLQGGCDGGNKSYELKTNQEFEYKGYAIPKGTLLIDNLWSVTKHYAINIIGFFTIQESNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQF2</accession>
    <name>M5FQF2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Krr1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_119760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623842.1">
        <property type="nucleotide sequence ID" value="XM_040770857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQF2"/>
    <dbReference type="STRING" id="1858805.M5FQF2"/>
    <dbReference type="GeneID" id="63685919"/>
    <dbReference type="HOGENOM" id="CLU_009647_2_0_1"/>
    <dbReference type="OMA" id="WDNYDPR"/>
    <dbReference type="OrthoDB" id="10252032at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="464"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="549"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="601" mass="69810" checksum="E0E88DFC49D76FEC" modified="2013-05-29" version="1">MDLFDDDETHKITINQHFAAAYAAKKEREELSILEEKYGSESQNDDDDDESEEDEDEYGDDITPAMDAAIFKTLSRIRRKDPIIYNQEKDVFQEEARRLASDLGGNRFPKKPSKETSKPVTLRDMTVQELLHPDQEESVVPTHAEEQATLRKETISAFKTAAVDDDVELLTLRNPANEMNDESYRRFLLDSVGETDMRTVLSSDVEETPKLADFRMPVGVAQEKHVRKRKRTGILDTPADEEFLLKYILNRGWIDRSEQRHPTLEEITAKPVEAVMQEKITEEDSDFEDITDQFESSYNFRFEEPHAAVITAHPRSIQSTVRRQDDSRKLQREKRRRRKAEEKLVKQEELKRLKALKRKEIEEKLKILGHVSGKHDIRTDELDLEGDFDPEAHDAQMRAVFDEEIYDDQHEQSKPTWDDEVDITNLLLKEAEKTERRQNKSKETNQTADVVDAPHAATSLDLRRKVDEYMDEYLGLDYNGMVGDQPTRFKYMEVPVTSFGLTPTDILLADDAELNTYMGMTKYAPYHPNPTDKRGKRYWQLKEALKGRSWSRDTKDEPKANSMTKRKGKKERARSRASNDVNVVQRSDCQDERLAKRQKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQJ2</accession>
    <name>M5FQJ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_96037</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="9">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="8">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626063.1">
        <property type="nucleotide sequence ID" value="XM_040777341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQJ2"/>
    <dbReference type="STRING" id="1858805.M5FQJ2"/>
    <dbReference type="GeneID" id="63692403"/>
    <dbReference type="HOGENOM" id="CLU_015739_0_0_1"/>
    <dbReference type="OMA" id="PYNSQDV"/>
    <dbReference type="OrthoDB" id="3341590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000018">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015328">
        <property type="entry name" value="DUF1965"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF20">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09248">
        <property type="entry name" value="DUF1965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00766">
        <property type="entry name" value="CUDAOXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0186">Copper</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7 9" id="KW-0801">TPQ</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067195" description="Amine oxidase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="13">
        <location>
            <begin position="86"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1965" evidence="14">
        <location>
            <begin position="258"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="12">
        <location>
            <begin position="337"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="7">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="8">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT99165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="782" mass="88336" checksum="AF58E64334C39657" modified="2013-05-29" version="1">MVHPTRLVCTLLAASLAIPASASPKAPWVKGPGKRPVTRREAAINQSRRDQPWNETDSCGTGVSNYTVKAPKKNIWLGLTEAEVAGITEFVHNQKSLNLTAVENATNWDNSLLLVELMLPNKTDALNYFDGGGAEPARHAHIEVDHRASVHNPAYLDYIVGPLPISNKTTVEPLAWPYTKGPGSSHNYAADDDARNDFMNNFGAELADITRALWNGTAMGLDNDTMSIWGIDPLFQEDGRTISWDTFWNNNNDVYDDSTLLPLGLFLKPDITGRDPSQWSNQGVLYNGEFYDTIDDFKSAFYSGNIQTFGPNEDEEWGRTDQRGPVNPTDWQSPPMLIQPAGQRFQVDVEQQYVQWMDFEFYIAFTRDTGIKLFDINFKGQRIIYEIGLQEALAHYGANDPVQSGTAYLDSYYGFGPYAFELVNGYDCPSYAFYLNSTFYADETTRTHLNNICLFEQDAGHPIQRHSSSQYVTITRNIFFTVRTVSTVGNYDYMLDYTFYMDGSLHVTVRASGYIQSAYFANNEEYGFHIHEYLSGSMHDHVLNFKVDLDILGEKNSLQNVSFVPATVEYPWSNGKTRNTMKLEKSFVTTETGIDYPYNSAALFAVVNKDKPNKYGELPGFRVLPSTAPVHLTVNAAHWAERNFWVTKQKDTEPRSSHPFNNQDVADLVVNFSKFVDDESIEQEDLVLWINAGMHHVPHTGDLPNTVFSTAWGSRINYHNGNVTEVATFGSETIQPECTVDLRDSFTDLWDYTGDVVVRKFPYDPNDPFFNTQSIVKRDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQT6</accession>
    <name>M5FQT6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624836.1">
        <property type="nucleotide sequence ID" value="XM_040773884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQT6"/>
    <dbReference type="STRING" id="1858805.M5FQT6"/>
    <dbReference type="GeneID" id="63688946"/>
    <dbReference type="HOGENOM" id="CLU_507151_0_0_1"/>
    <dbReference type="OrthoDB" id="10646236at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="537" mass="59527" checksum="6C7261313C7540F6" modified="2013-05-29" version="1">MSSLSEVPGQIDERDDEEEDDVSVFSRMVPTRDVTPMPVRHLDARASTPLSNTPSDLFSGDYDLEDSHPELEPVTMRNPFEGLALPTRHDFRLPVHLELSQPPAVGHHVEMVPPVEVSDITSVPVSQPSLIVPHRPEQNVGVAYDSGSVLQDAQEPGDGISPARGPTDLKAETLFPRIIDQEAESTRVVTDVEAQTGQRFEEEHVMLEVLRSPSVTEPTAEINGASPLEREKEFVAENMVGEPLSDALEIVPHHHGPSIIPARSETQASRTSSSYVGHRPLTRAQCHWEKIRVTIKDTPSRVFFVTICNINEAQELDGIIREGPAVRSEWDQALEEIPPLIAEGMADVLAKLEMYIGTSPLGAARWLPVAQDEVEGVRAEFAKLEYTRKVLKRPRTEDEEGKDSSEPLQKKPRTPTPLDPLDTSSKISSEPRRTRLQLTPSSNTRGKGHQKSLSVDGRLTPTREIPDVTRNSSSTIPRSSALSSSPGLARYPLRSHDQEEHEEHEERERREEQLASSSNTPSTPPRRTVGRRKQVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQW7</accession>
    <name>M5FQW7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626293.1">
        <property type="nucleotide sequence ID" value="XM_040773472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQW7"/>
    <dbReference type="GeneID" id="63688534"/>
    <dbReference type="HOGENOM" id="CLU_2580241_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="81" mass="8501" checksum="47FB25EDC28069ED" modified="2013-05-29" version="1" fragment="single">MSTPTSNKTSVSMNNTAGMGTSPTASTVQPQNPLEQEHSGESDVEESRVSEDEAIPPVIPRVIQSRISQTALPPSGPPLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQX3</accession>
    <name>M5FQX3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein HIR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_118135</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626308.1">
        <property type="nucleotide sequence ID" value="XM_040770529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQX3"/>
    <dbReference type="STRING" id="1858805.M5FQX3"/>
    <dbReference type="GeneID" id="63685591"/>
    <dbReference type="HOGENOM" id="CLU_004372_3_0_1"/>
    <dbReference type="OMA" id="RGSWDGD"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="15">
        <location>
            <begin position="29"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="14">
        <location>
            <begin position="657"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="401"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJT99410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="910" mass="99723" checksum="A13E3329CD1D93FF" modified="2013-05-29" version="1">MQLIKPAWVMHTDEKKKRLPIFSLHVHGDGSRLATGGLDSKVRIWSTAAILDEHNTMPKSLCTLTMHVGPVLCVRWSHSGRLLASGSDDGLVMIWDLDPSGAGKVFGEEEVNVEGWKALRRLAGHESDVSDLSWSPQDRFLASVSMDSSVIIWDDRVAKLVGHQGFVKGVCWDPVGQYLATQSDDKTVRIWRTTDWACERVVTQPFELSPASTFFRRLSWSPDGAHITAANAMNGPVFVAAVISRKEWTSDISLVGHENTVEVASYNPHLFVRDESKPVDSHNICSVLALGADDRSVSVWQTNQARPLLVALDVFDRNVLDLSWSFDGLTLYACSSDGTIAVMNFSPSELRGIAPHDVQLQYLKGYKFTSPMNLTYQAEAPQPIPLPPQFVAPAQRVQPLPAQPPINVRGTQEVTRTKDGKRRIRPVLLSQGSSTSLPPPVHPYQQPLQNGIHIQPQPTAQLAYTQPVLQHAMAEPSNPFTSTPLSVSQPGSYASSMPLSGQAGLADDDVQMVDSWEPAEPASTAGGSSPRKGRTLGGDRVREPIVVRELLGSTSAVMPIVNLPSASGATRTSEPVLKAPGLKTYVAAPMEGAKEGDVLEGRNPDEPDKPSDVQLYQNKTVQWLDYLPSRIVAVASTSVFFVAACIDGGITVYSQTGRRMLPTLMLDSRAVFLQGLKQYLLAITEQGTLAVWNVKSAQAIVPPSSIRHLLISQLLSVQLRPNGVPVLNFSDGTAFSYDPGLSCWHKLSDAWFARGSDSWDAARTRASRPAAPRGPIATLEAAISEAKPLELLIENKPEWWSAATTLAHLESRMFGAKALDSPGEYKLALLGYARRLADEGFRGKAEELIKELCGPVYWRLRKEPWEPTVLGMQKRDLLKEVLSIFARSKTLVKLGSDYQDLMKRIVVEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRC9</accession>
    <name>M5FRC9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_69423</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626568.1">
        <property type="nucleotide sequence ID" value="XM_040775901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRC9"/>
    <dbReference type="STRING" id="1858805.M5FRC9"/>
    <dbReference type="GeneID" id="63690963"/>
    <dbReference type="HOGENOM" id="CLU_021377_1_0_1"/>
    <dbReference type="OMA" id="QIPAQKD"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="92"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="11">
        <location>
            <begin position="476"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="544" mass="60774" checksum="DD20E0296BEC8F8E" modified="2013-05-29" version="1">MFAARANFRLVALNRQLVLKHTPIFPSTSARLYATAPQTVHAARQSRWRSFLQTVGRLTLATVVLSAGAFVYVVQRDRNPGEQLAHDPSKKTIVVLGSGWAATSLLKKLDTEYYNVVVISPHNYFLFTPLLPSVSVGTLEARSVIQPTRYITRHKTRRVEVYEGEAKSVDVKNKTVTFEDNSDIKGAVSTTTIPYDYLIYAVGAENQTFGIKGIREHACFLKELPDAEKLRTRLMDCVETAAFKGQAPSEIDRLMHIIVVGGGPTGVEFAGELHDFLVDDLHSWYPELANHLHISLIEALPNVLPVFSKQLIQYTESTFKANKIDILTRTMVKEVREKTVLVQGENKELREIPYGLLVWAAGNTSRQITRDLMAQLPNVQNQRRGLLVDDHLRLLGADGVFALGDCTATLYAPTAQVASQQGKYIGRVLEQMAKKEQLEATLRSLRVSPDAKPEEIEAVVKQINKVANIKPFHYSHQGSLAYIGSEKAVADLPLFNGNLATGGVATFLFWRSAYISNLLSLRNRFLVLNDWMKVKLFGRDVSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRP9</accession>
    <name>M5FRP9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin kinase</fullName>
            <ecNumber evidence="4">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_25034</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="4"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624577.1">
        <property type="nucleotide sequence ID" value="XM_040773975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRP9"/>
    <dbReference type="STRING" id="1858805.M5FRP9"/>
    <dbReference type="GeneID" id="63689037"/>
    <dbReference type="HOGENOM" id="CLU_048437_3_2_1"/>
    <dbReference type="OMA" id="NGEVHKM"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="13">
        <location>
            <begin position="36"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="22026" checksum="7523D6527BF8DC37" modified="2013-05-29" version="1">MAAEHHPHTEPLSTEQYRASRPNICGPDSGPEEPFPIVMYGLVQPGFGRGSKELGCPTANLPDDAIELMASKCQHGIYYGYARVHQPPHGKPGDLEETEIEVYPMVMSLGNNPYYNNEKMTAEVHVIHEFEHDFYGHEISVLVLGYIRPELDYTSRDALKEDIATDIRVTLNSVARPTYNKYREDAHWTRAQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRZ1</accession>
    <name>M5FRZ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624757.1">
        <property type="nucleotide sequence ID" value="XM_040773861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRZ1"/>
    <dbReference type="STRING" id="1858805.M5FRZ1"/>
    <dbReference type="GeneID" id="63688923"/>
    <dbReference type="HOGENOM" id="CLU_039854_1_0_1"/>
    <dbReference type="OMA" id="FFNAWMS"/>
    <dbReference type="OrthoDB" id="2127032at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000030">
        <property type="entry name" value="NAD binding Rossmann fold oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF6">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="33"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="420" mass="46233" checksum="8CB33ED5CFD07A08" modified="2013-05-29" version="1">MEANLSKLNCLMCGTGEYTTGWTGAGASQSDKKVGVVGLTLFDLRRLGKVNALSMVGTNGAKFPDIRAHLQSKIADVYKDFDVGFKSYPEGDKQDTEAYKTAIDALKPGDAVIIFTPDNTHFAIALYALERKLHVLLTKPATQLLEHHQKLIDVAEKNGVVCFVEHHKRFDPAYSDARGRAQALGEFNFFSSWMSQPKHQLITFKEWAGRDSDISYYLNSHHIDIHCWIMGDKGVPTRVVASASKGIATSEPFNCVPQAEDTITLLVDWESTTSAKHRGTAVYTASWTAPMGAGIHSGQHFHYMGAKGDVHVDQAHRGYDVTVDGSGLAFYNPFYMKYTPSETGHFDGQRGYGYISIEKFVDAARMVNAGVAKPADFDKQGLPTILNTVLTTAILHAGRISLDEKRPVQIKKQGNGWALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS14</accession>
    <name>M5FS14_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PIG-P-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_58572</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624797.1">
        <property type="nucleotide sequence ID" value="XM_040775504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS14"/>
    <dbReference type="STRING" id="1858805.M5FS14"/>
    <dbReference type="GeneID" id="63690566"/>
    <dbReference type="HOGENOM" id="CLU_081616_2_0_1"/>
    <dbReference type="OMA" id="LYVLWAY"/>
    <dbReference type="OrthoDB" id="690928at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="7">
        <location>
            <begin position="37"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="19036" checksum="07F5D0274A15732C" modified="2013-05-29" version="1">MPPSPPASPTSPLSPIAPYPPPTSPSSPASQPRTRAREVYGFTAYVGTLLLFVLYVVWAVTPDAWLERIGVEWYPNREWAILVPAWTTVVVLLTYLTYLGLALSATPSFTDLTTITDTRAHILKMEGDVNPLLHYSRPDAVPHEFDIPLGTVNRVLYGKRPLSSVAPCQATIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS39</accession>
    <name>M5FS39_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
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            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
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            <end position="23"/>
        </location>
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    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="324" mass="35962" checksum="4D4CC49041E1132F" modified="2013-05-29" version="1" fragment="single">MPEDVDETELSEDESDEAEPEDPLVTHLFEQLEDMRQKLYQAEMRCAVIESETREEVTREMEGRMRAMERMFSERVIFDAEQNEAKIDSKIDLVNRAMMISTKRMSQDQDDSVGEVEDQLISFGQESNIFLDDDHYIDCGINDHDSNEENTLSDSKLSEQEESGDACFQAQSDEWVPSDDGANSSESSMSRSRPTRSRARRTSSAQRRGRSSASAGIAVRGSIGKENSERAVTAGTRPSCARKTPILCVRSEDDASWNSILQFEAPNKQPQNTSKQLITTTAITESSNGTAMMKAEKTGEGLVIPHNGPRGAIISVMGVALDEA</sequence>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
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                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
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                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
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            <strain evidence="1 2">DJM-731 SS1</strain>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lundell T."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <source>
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    <sequence length="114" mass="12290" checksum="F08695CF37312EB8" modified="2013-05-29" version="1">MPCASGRRGSHHLPLNVSIVLNADVTAASLDVEAADCKPAEEEETLPRLIAATPSAGICYAWTAGEECDYMQAVQFLAGRKGLTWAQQDKLVGFAKEADPMMQELMCICTSMKI</sequence>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Glotzer D."/>
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                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Kohler A."/>
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                <person name="Nagy L.G."/>
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                <person name="Patyshakuliyeva A."/>
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                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
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    <comment type="function">
        <text evidence="3">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
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        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
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        <text evidence="3">Nucleus and/or cytoplasm.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040775852.1"/>
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    <dbReference type="STRING" id="1858805.M5FTC7"/>
    <dbReference type="GeneID" id="63690914"/>
    <dbReference type="HOGENOM" id="CLU_007630_0_0_1"/>
    <dbReference type="OMA" id="VQLWSVY"/>
    <dbReference type="OrthoDB" id="26282at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180010">
        <property type="term" value="P:co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="5">
        <location>
            <begin position="169"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="750"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="891"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="750"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="780"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="809"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="903"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU369035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="934" mass="103704" checksum="F32584CA6050CC86" modified="2013-05-29" version="1">MSAPELQTEEDSINAVLGAASSPSPSEMDVENAAAHGVGVHVEVEDDIGVEGASDADADGEPDVDADGEADLDVQAITVEQQDPSNETGPNGSTENGTNGVYLPSAADYSPSGPSAPVPLPDVPPSPVKQEFSTPPVLRPEIPASITVAIRAASGRQSVTPGVEDGPMDRIEQLRQRVKDDPFDAEAHLALVSAAEAAGDVDQIKQAYEGLLGPYAGAATHQISYLSHFLNNAADFPYAESLFARFLRASPSVELWKFYLTYIRRVNPGDAGRETVKKAYEFALGYIGFDKDSGEIWRDYLQFLKEQPTLSTWEEQQKTDVLRRTYQRCVVIPLENIEALWREFNSFENAQNKQTAKRFLEQYSPAYITARSSMKTLRQLLDPITRPLANGLPLRPTWTEQDKKYAMDWKAYLMWEESNPLDLDDTAALATRVQAAYRKAVGWARFYPEVWYMAYNYLVSNSKIEEGAVLLRSGCEGNPTSFLLHFATAELEEGRKNYPAAHATFNNLITNLTSQVKQLQTSIEAEAELAKGAEIDTSTLANSDSLSEDFRKANEEREERGQRVWARRGREFEDLKAGLQVAWIMLMRFARRAEGLKAARTVFGRARKSEWAGWQVFEASALMEYHCTKASDVAGKIFELGLKSFADNVDFVLRYLGFLISINDDANARALFERFIPTFPADKARPLWERWARYEYNFGDLAATQKLEKRIAEAFPNDPPTKRFAQKYEYLNMNTIRDFDMGFGYRPPAPVQVPPLPPAPTLPPPQPAKRPVSPSPPPAARREPPKRPREPSPDRRGPIKKSRQASPPPRDRIPDRGWQERDNRGYQSPRPRSPPLPSYEDRVPAAPAAPSGAVPALIAALLAKLPSANVFDGPVFRTDDLMQVFRNSVIPGGQMLPAPSGPPRARSPQPARGGRPPPDYGPYRGPNSGPGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTD6</accession>
    <name>M5FTD6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_17484</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626211.1">
        <property type="nucleotide sequence ID" value="XM_040771289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTD6"/>
    <dbReference type="STRING" id="1858805.M5FTD6"/>
    <dbReference type="GeneID" id="63686351"/>
    <dbReference type="HOGENOM" id="CLU_078858_0_0_1"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="268521at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="229" mass="24573" checksum="C6D94D07A7CFC65B" modified="2013-05-29" version="1">MASLLSSFARFSLSSPPSPSLLPRHSIISPLPAYSQLRFAGNLAPNRVKHRKAHKGRVPIPIGGSLKGTTLSHGNFGIRVKGNGTRLSAKQLQSADTALKRKLRIVKGAKTWLRVFPDIPVCIKGNETRMGKGKGNFDHWACRCPTGRVLFEVGGDVSEQLARDALRLVADKLPCKVEFITRRDGPRLGTLVLPVGTKSGGPGVLETLVEEGKIPLVPEAAPPVAEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTE5</accession>
    <name>M5FTE5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="3">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_22761</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="3"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627803.1">
        <property type="nucleotide sequence ID" value="XM_040772942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTE5"/>
    <dbReference type="STRING" id="1858805.M5FTE5"/>
    <dbReference type="GeneID" id="63688004"/>
    <dbReference type="HOGENOM" id="CLU_000688_21_2_1"/>
    <dbReference type="OMA" id="IEWTNEF"/>
    <dbReference type="OrthoDB" id="29072at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:endosomal transport"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02678">
        <property type="entry name" value="MIT_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="AAA_lid_3"/>
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    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
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    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045253">
        <property type="entry name" value="VPS4_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="15">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="165"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="76"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU00906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="442" mass="48843" checksum="DE15723E04693ED4" modified="2013-05-29" version="1">MGANSNFLDKAIDLVQKAIDEDVAQNYAEAYKLYQNALDYFMMALKYEKNDKLKELIKNKLKEYLDRAERLKEHLAQAQEKRQRSAMGADGKSTGGGGGAGKNKDDDDDPDTKKLRAGLSGAILTETPNVRWDDVAGLEAAKEALKEAVILPIKFPHLFTGKRTPWRGILLYGPPGTGKSFLAKAVATEAKSTFFSVSSSDLVSKWMGESERLVKQLFTMARESKPSIIFIDEVDSLCGTRGEGESEASRRIKTEFLVQMDGVGKDGGGVLVLGATNIPWMLDPAIKRRFERRIYIPLPGPEARRRMFELNIGTTPNVLVKDDYRTLAEKTTGYSGSDIAIVVRDALMEPVRKVLSATHFKSVQVPNPSPPPSEIAKWTPCSPGDPDAVEKSWGDVEADELLEPVLGLNDFVRAVQAVRPTVTDEDVRRQMEWTNESGESAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTP4</accession>
    <name>M5FTP4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626376.1">
        <property type="nucleotide sequence ID" value="XM_040773314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTP4"/>
    <dbReference type="STRING" id="1858805.M5FTP4"/>
    <dbReference type="GeneID" id="63688376"/>
    <dbReference type="HOGENOM" id="CLU_395342_0_0_1"/>
    <dbReference type="OMA" id="CVLKDCW"/>
    <dbReference type="OrthoDB" id="3260094at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="206"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="778" mass="87131" checksum="4505DBE597371B9E" modified="2013-05-29" version="1">MEGTTPSMPSTPPQRTNTPSTSCVHDTPVCGRATDSVVYQTGTLRERRQLVATTLGDIREYCNTNWWAQVLPKWPKDAPNDLAESIYAKLVQKGEYVEEEQRWKSFPVDPARDQRPETAVHRDWKLVVDQIVQALHCVYRPQVDALEYWQQPSLAPESQVQNLTRPDSYMIRLAKMLAKMATAEPDVPDDGSKTGETEASSLGVMKKLQNPKHSWKDICEVGEFKKVDSTSQNGDTAVEQVIWSIHHMLREDSARRFVYGSTFIGREFRSFLGSRIGVFASQAVDVHHDPKSIIQYYVRMMCADDISLGWDASMTRNEEGQIVFSLETGNKAPPLVLTATRELFSQAAENIRGRATRVFEVTRDSEGSVFALKIGWIEEGRLTEGQIIKNMKESLRKVDPNDQTLEQHVLDIEAEGVVTFPDVGEDTTRLPLGNMDINGDKCAVMHLPITASMQQIISLSSHPGSIGGFEEKMTGVPLRSVSKVHREHRWTLYKAVLKPIWQLDDLRDMCCGLTDVGRALSAVAKAGYVHRDPSAGNGYWDERKKRGYLSDFEYAVPWEGERAGHGVRTGTPMFMPLEVAKGAWEFPTPIRVSAISRGAAQVPEFLATPLHDLESWAWVWLWAVVRFQPVGAAGPTECQRILSSFLFNGNPANSSRGTYIRWRACMAGKKLWSLQDEGGSPLAFSVVADLANTLFKVVHAEHHEYQKLWTPDVFAEAWESALNLCIETTLPGNIPIKPWSDNPMLGGLVHRTDRAGSQHKRNASQSVSRETAKRSKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTT7</accession>
    <name>M5FTT7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627973.1">
        <property type="nucleotide sequence ID" value="XM_040772991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTT7"/>
    <dbReference type="GeneID" id="63688053"/>
    <dbReference type="HOGENOM" id="CLU_888582_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="313" mass="34163" checksum="DB1D2DE5F0A9B2F3" modified="2013-05-29" version="1">MSGNLDVDLRSDILGRVGTHISTDEPEPVSVDTAKPNSATSSEGNPICDEGACIKACTSNASGVACNTHTALYGDPVNNKDQGEDPENSVVLERTSRVQQTQEALCVDPVNPSEITSRTVSTSSVPMDLDVRIPPVKDRARTNYKTVNIKLPDFETGEQYEKRVAARRALLKKVVQPRWSPPPYDPTYVPYSAPPEERVIEALPVYTPTPVPGRTAPKQQKQIKITLPDFETGPQYEARMRARAMNRKTGGAQCSTTSPGPSIPNSDTRNVGSNVYTRLPTAENNGDNEGSGEQSHTNSWGSWLSWLTWTSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUD1</accession>
    <name>M5FUD1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_119885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623739.1">
        <property type="nucleotide sequence ID" value="XM_040770885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUD1"/>
    <dbReference type="STRING" id="1858805.M5FUD1"/>
    <dbReference type="GeneID" id="63685947"/>
    <dbReference type="HOGENOM" id="CLU_020927_0_0_1"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15535">
        <property type="entry name" value="PHD1_Rco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15534">
        <property type="entry name" value="PHD2_PHF12_Rco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052819">
        <property type="entry name" value="Chromatin_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="201"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="604"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="669"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="671"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="764" mass="83012" checksum="386B62A67990AA50" modified="2013-05-29" version="1">MSSLPLSLPALNPPPAIRQPADLPTSDPSLATELMPAPPPLSYVTNPSSHHGQRLPILTRSGANRYLPSVDLGTTYTGHGILPPGAGSLETPPPTVLGEGGEPVKPKRNTRGAALGPNAKSTAVNRVQRVTRSSRPATDSPAPGSHSTPPPPVAGPSGTTHAVEEVDDAPERPPKRQKVENKGKGKEKEPIKEGEPIQMNKDYCETCGGIGEFICCDGCTRSYHFLCLNPPVELDDIPEDKWYCGVCLYNHKSHPKLTNRFLGALAQKVESESPKIFKLPDPIREYFKSVTTGLTGEYVQQGQARGGRLNKYGAVEERDPYRLKDKNGKPILCYKCKGPAVPVTLPEAQRKTRAGSVKTITRPIISCDFCSQHWHYDCLEPPLVHPPANWKKWQCPLHVEQLFPMKRIPAKGVKTVDVNQRNKPNNGIIDVIFPEEDLSSMKVENVVINGKRYRIPEKTIILDFWDALQGKRPEPAGTESVRTSVAPTDVLTPLPNPALTRTAGLDSAFSSPLSSLSSLSSVSDEDMLSDTLSEQLEEDHKFPPSAVETSPVLRGMSTPPQQVGERHINEHDAAEILVSFSHGTAPNIPELPVGLGIFQSTPLTDRTNHEIERPSTPPMPRKVLRSATKTNGSSTGSARPSNATPGSVAKGSILSSAREQLKNDVHMALLPSSRPSSPMIVSSTPSSPQPKPGITVKQKEDGSFTLRLPSLKRTLSHQNNHAMPSKAVEEDASSLPLEEINRLQAVRRLLQKKGESALLKFLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUE8</accession>
    <name>M5FUE8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626746.1">
        <property type="nucleotide sequence ID" value="XM_040773229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUE8"/>
    <dbReference type="STRING" id="1858805.M5FUE8"/>
    <dbReference type="GeneID" id="63688291"/>
    <dbReference type="HOGENOM" id="CLU_019028_1_0_1"/>
    <dbReference type="OMA" id="PISFYRV"/>
    <dbReference type="OrthoDB" id="7722975at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000043">
        <property type="entry name" value="Ser/Thr protein phosphatase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053828">
        <property type="entry name" value="Nucleosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014485">
        <property type="entry name" value="Pesterase_C1039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21953">
        <property type="entry name" value="NadN_nucleosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017316">
        <property type="entry name" value="Pesterase_C1039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067306" evidence="1">
        <location>
            <begin position="17"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Putative 5'-nucleotidase C-terminal" evidence="3">
        <location>
            <begin position="364"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="599" mass="67679" checksum="53647F6ACDA5399F" modified="2013-05-29" version="1">MMHLLLLLTSLIVVRASQPGATQSSAWPARPLVWGDVNFLFTTDTHGWLMGHTKSGPPEPNYSADFGDFLSFTTHMKSLAAEKGVDLLLIDSGDLHDGTGLTDGAPPGQPNAHESNKFIMRLPYDVLTPGNHELYQYASALDTYKSFVPHWSGKYISSNVHLTLPNTTNLIPFGSPYRKFLTTQGRRVTAFGVLFHFTMNARGTQVQSVEELVEQPWFAQAVEEEPDMFVVAGHMPVHMEEDPEVNVNDWPIVYYAIRQRHPETAIFIFGGHSHKRNCTVMDEHAIAIQGGRYMETVGWLSANLTEGGGYTRRYLDTNRNTYQYHTGTDEEDFDTLEGIELTQYITQLADVWNLHEVFGYAPQDWYLDRVEFPHKNSVLTLFLNDVLPTVLRLGAPERSNIPLLAIFNRGSIRYDIYQGPFTRNDQYTVMPFKNQFFYVTVPWAVGRRVVDEANKKREDQARLRDAMRMAMPSLPQPSEVPFPLPGAQTVLGGPKEPKEDEPLTLGYVTQDLCEGYADDTPHLSIGGLDRADDFHSSPPLPISDDTLMDVVFPSFVAQPIVDALNRLFPGQNYTVAGLEKYMKWGSEDVFEVYAREKWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUF3</accession>
    <name>M5FUF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623764.1">
        <property type="nucleotide sequence ID" value="XM_040769371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUF3"/>
    <dbReference type="GeneID" id="63684433"/>
    <dbReference type="HOGENOM" id="CLU_2015196_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="13503" checksum="A8E5A355B36AD2FF" modified="2013-05-29" version="1">MSQGWGTQPPEIPKPDLEAIRATLVSSAASIESGRLAQGVHREMGLFLATPLISFDQLIAEKARFVVDWLKDCQTVEVNSDNHPSMVLGNPGAFKTAHPRLLVLHESAWEPSLAQDITFKVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUR0</accession>
    <name>M5FUR0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_109945</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626122.1">
        <property type="nucleotide sequence ID" value="XM_040768972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUR0"/>
    <dbReference type="STRING" id="1858805.M5FUR0"/>
    <dbReference type="GeneID" id="63684034"/>
    <dbReference type="HOGENOM" id="CLU_004131_2_0_1"/>
    <dbReference type="OMA" id="ICNDIRI"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000109">
        <property type="entry name" value="Related to MLH1-DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="242"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="368"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="630" mass="70087" checksum="8C3293794CD25100" modified="2013-05-29" version="1">MAASAVDPKPIHRLEESLINRIAAGEIIHRPANALKELLENALDAGATQIKITAKDGGLKLLQIVDNGSGIRRADLPLLAARFCTSKLSTFSDLSKLQTYGFRGEALASISHVAHLNVVTKTREDSCAWRASYSDGLLAPAKAGTSADPKPCAGNDGTTIAVEDIFYNIPLGLRALKSPSDEYARILDVVQRYAIQPKRLLPVQEGMSSYRLPLLVLNSTYQTGSNTADVSTPSSRTVKSAIKTIYGPNVAKELLEAQAEAGPEDEFEWQAEAWLISANYHAKKPAFLLFINQSARLGLAFRASLDIDPSKVDVNVHPTKREVHFLDEEAITQKVADSMQVVLAANAQSRTFQYQTVLTGHRPFKSQGKMKRIDLRKEQIAAGSDEDMEREDELEDEENEQDLDLERPRAGPSSSLKPSRKPSQPSYKKSETILRREPWTRYLAEIIGEHTYVGIASMSLCLSLVQSSTKLFLINHAALSEELFYQLGLIVEELVRLAVGAEAAIKEQGLNPGKIIKSILKPIMPQRGMLAEYFSLKITSSVNWTSESECFSTFLRELAYFYAPGSVVREKEAPAPEEQEQGKRKGEEWQIEHVLFPAFRKYLVPPRGLLERDMVQVAELRDLYRVFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWE1</accession>
    <name>M5FWE1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624604.1">
        <property type="nucleotide sequence ID" value="XM_040773986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWE1"/>
    <dbReference type="GeneID" id="63689048"/>
    <dbReference type="HOGENOM" id="CLU_545832_0_0_1"/>
    <dbReference type="OrthoDB" id="10442557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="58016" checksum="BA0E8D7EC1BD100F" modified="2013-05-29" version="1" fragment="single">MPLQDTLVCLYMRRRQLSSPYAVSVPPLAVAVVADRASFSPKAQLKGFRIKVPDDIWNMIFRLLFDSGKSVLNVSLSCRRFYILTLPLLFKRLSFHHDRNHHAETLCELVQKRRHLQNYVQSVDINCITWNDAHLMVASFPPPCIVQLLGILTNLQSVSLSGTVLSYRGALLLAETKTLRQFSISSSCRLGKNMFADIPRRKNHSIERLTIGELAYDKPEDLVDWLYLVLSNTLTDLHVIGGLTTGKFFIESLLQELVLNTLRRLHIEYIDGAILYEIVARQQRLEELHFFCSDPLFVVDSRLPPNISSWSGPAFLATHFIPDSEINKVRLWMQDMSEQGRHVQDKPLAWVYETSIKHARRPIQSLEILHFEWNQCLMDSIPRVFPDLERLALFFIDRPDMDYLENKLAAKLAMMKHLRYLSMGTEGTIPAVRPANDIPWCYNNLLKWTENCPTLKQVECRVLNLWIDWRRFGHAEWKGFMKGEMVLDERELLKLHIYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWH6</accession>
    <name>M5FWH6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624654.1">
        <property type="nucleotide sequence ID" value="XM_040773834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWH6"/>
    <dbReference type="STRING" id="1858805.M5FWH6"/>
    <dbReference type="GeneID" id="63688896"/>
    <dbReference type="HOGENOM" id="CLU_039532_2_0_1"/>
    <dbReference type="OMA" id="KVHMTAD"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="2">
        <location>
            <begin position="102"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="196" mass="21972" checksum="8DE2F5C647EEF6C4" modified="2013-05-29" version="1">MTSQPRYEWYQTDGKTTITVYVKNAEADKVKIEFAPKSLVFSYGDQQLVLEPLPTEINTDASSYTVMKMKVEIGLVKKVAGRWQAITGEQEGTVQHISPEPSTSNRRKARKNWDAVTTEILSSEKEKSVSDDPNIGGDVAANEMFAKLYADADEDVKKAMIKSYTESNGTSLSMNWDEVKKARVEPYKSKDDDDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWI1</accession>
    <name>M5FWI1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_68234</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627626.1">
        <property type="nucleotide sequence ID" value="XM_040775867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWI1"/>
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    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
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        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067245" description="Cytochrome P450" evidence="12">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16768" checksum="66133B015AC6DFB9" modified="2013-05-29" version="1">MPAYILFLFALLILLLFSIRRRSHGAAYPPGPQGIPVLGNVLELPRSLLFLKLAEWAQVQGPLYTVNILGQPLVIINCAKEAADLLDRSSLITGGRPSLIKASDFLTRGLVIPLIDKGERWRLMRKATHERLNVRDTKSFVQSKKTKLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWI8</accession>
    <name>M5FWI8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit TIM54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_80937</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM54 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627636.1">
        <property type="nucleotide sequence ID" value="XM_040776483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWI8"/>
    <dbReference type="STRING" id="1858805.M5FWI8"/>
    <dbReference type="GeneID" id="63691545"/>
    <dbReference type="HOGENOM" id="CLU_033744_0_0_1"/>
    <dbReference type="OMA" id="RNWMIFF"/>
    <dbReference type="OrthoDB" id="5598305at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021056">
        <property type="entry name" value="Mt_import_IM_translocase_Tim54"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11711">
        <property type="entry name" value="Tim54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="236"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="471" mass="52738" checksum="872DEDA83573BB66" modified="2013-05-29" version="1">MSSPTPSSSASSSAPTAAVSETSGIRAVLRYSGIPPSLLRVPKFRLPSRNWLIFLGVSGSLASLFIYDRRECKRIRREACEQVRWMADLPLDPQATVKCIKVLAAKQPGDDESAKGMLYFRKWVKPILVAAAVDYDMIVGERHGSITNLVSKEIQHKRLIRAGFLQPDAGPTPSQSAQARQERELQGGVVLVGRATFKEYLEGLKRGYGEPASLGRGGRERGEDEEDALVSKALEGDGVFDEPHMADSTSSDSDSTIGTPQPVSPQLQSFRNPLLPSFELRPLARLSPSPSVVLPPETSLPPQPALLLLPFRNLVGISLIPRQIWGFFNRRYYAKSGAESALILLKGATRPFDPETDLEFGKDAEGFWPGKFDKVDEEVAKRKAEYYKELTKKLATARELANGTHKPTKEEERNPPKTEQELRQERFDKEKRWKRELEGWEVVKRSKRPAWEQGWEEQMRVFEQEGVRGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWP4</accession>
    <name>M5FWP4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627711.1">
        <property type="nucleotide sequence ID" value="XM_040768751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWP4"/>
    <dbReference type="GeneID" id="63683813"/>
    <dbReference type="HOGENOM" id="CLU_1427930_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21399" checksum="7AF544988B319BBE" modified="2013-05-29" version="1">MHLDKKFELEEVDGVVGGGGVEEEEELVVVVDEKEEDQEELDKSPIQRTLRVLAEFTTSRADIRVIALHSSYLLPRFPYVFHCSSRPLASDPVPPPLPMEVPRDEVEAQDYRTFSSTTLGLESRRNETCFMNAQLFALLQVEKDGAKSRMGTERPIILDPVVLVFRATVWANTHRLGSESVKTRSDAVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWQ4</accession>
    <name>M5FWQ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7 8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_84222</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the PPP phosphatase family. PP-Z subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7 8"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624769.1">
        <property type="nucleotide sequence ID" value="XM_040776666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWQ4"/>
    <dbReference type="STRING" id="1858805.M5FWQ4"/>
    <dbReference type="GeneID" id="63691728"/>
    <dbReference type="HOGENOM" id="CLU_004962_0_8_1"/>
    <dbReference type="OMA" id="DWTENDR"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011159">
        <property type="entry name" value="PPPtase_PPZ/Ppq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000909">
        <property type="entry name" value="PPPtase_PPZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="316"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="512" mass="55461" checksum="0C070D48796A6A78" modified="2013-05-29" version="1">MGNQPSKKMKRFSSKEPSSHTHADDALPPPMPLPSAVHKDKDSKAASNGVDQASSTTSKDAKEGKDSQSLGSLRSRSQSASRSNGTTNGQSVGTTRAPPPPAINVIPTLTTTTAEATSSPRPKNGPLKRMPSPGPPTASPPGDSPPDDAQSPPVDPPTNPTILANANPNAPFGASLPPSASPISASFSASSVPASANASTIDIDGLISRLISTAYTGKVSKSLPLKTSEITSICLAARDIFLSQPTLIELSPPVKIVGDVHGQYADLIRLFEMCGFPPAANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFMLRGNHECANVTRVYGFYDECKRRASLKVWKTFIDVFNALPIASIVASKIFCVHGGLSPSLNNMDDIRRIARPTDVPDYGLLNDLLWSDPSDTAQDWEDNERGVSFCFGKRVIQDFLERYDMDLVCRAHMVVEDGYEFWNDRTLVTVFSAPNYCGEFDNYGACMSVSEDLLCAFELLKPLDGPALRKEMTKAKRKSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX11</accession>
    <name>M5FX11_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT98001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624899.1">
        <property type="nucleotide sequence ID" value="XM_040773908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX11"/>
    <dbReference type="GeneID" id="63688970"/>
    <dbReference type="HOGENOM" id="CLU_2020673_0_0_1"/>
    <dbReference type="OrthoDB" id="2973282at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="13466" checksum="BFA934D9247BC9E6" modified="2013-05-29" version="1" fragment="single">MLYANAIALCDALAPHLLLLPTPPLTPSPSPPPDADSDSEGVKGVVSLSHPLQPHLLRTRRLRNQLLPPTSRLPDDLLSYIFSLPSTLWSAGESVHFADQVSHVSHRWRAVALRTPNAWSTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX50</accession>
    <name>M5FX50_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629455.1">
        <property type="nucleotide sequence ID" value="XM_040772479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX50"/>
    <dbReference type="GeneID" id="63687541"/>
    <dbReference type="HOGENOM" id="CLU_2469033_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="10139" checksum="9C9A676E640A2CCE" modified="2013-05-29" version="1">MAPTKHSLCSITDRREAESLTFNFLLHRPNPWPPSAFRMPPPQKGASDFGRLFDHPDHSPLSLSLSPLVIPLRFQKGYRQLNYHKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX55</accession>
    <name>M5FX55_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_94372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067298" evidence="1">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="22964" checksum="68689EA491531E83" modified="2013-05-29" version="1">MLTLNRLTLALALIGGILAAPAKRTVAYYNPNNGGGSEVDIVSPGLGEPLNVISDPLLTCSDLLTNNFLSFAQDVGFSTECLGIHLGDPQQANLGDGNGAVDQLVEYRENYNLGGTCLESLIGGNHLRGWIQNGPSANSGAWFLAVSQEENVAEGHNIVPNGYNIGRDNLVANANAWAADQSAYSLTVEYVSGLLPSGSNGINHGISQDGQVAVITVTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX79</accession>
    <name>M5FX79_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit A</fullName>
            <shortName evidence="6">eIF3a</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 110 kDa subunit homolog</fullName>
            <shortName evidence="6">eIF3 p110</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Translation initiation factor eIF3, p110 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIF32</name>
        <name evidence="9" type="ORF">DACRYDRAFT_24618</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-3 subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX79"/>
    <dbReference type="STRING" id="1858805.M5FX79"/>
    <dbReference type="HOGENOM" id="CLU_002096_2_1_1"/>
    <dbReference type="OMA" id="EHITNKR"/>
    <dbReference type="OrthoDB" id="18884at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.10">
        <property type="entry name" value="UVR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03000">
        <property type="entry name" value="eIF3a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027512">
        <property type="entry name" value="EIF3A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054711">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22591">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="376"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="614"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="798"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="798"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="913"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="979"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1040" mass="118200" checksum="A9864D02CB34EAD2" modified="2013-05-29" version="1">MPPFSRPEAVLKQAEHLITVHQQPAALQLLSELFTMKKFRSTALSALEPIVLRFVQLCVDMRKGRIAKEGLMQYKNIAQNSSVTSVETVVKKFLQISEEKLEEARKEADRLYEEKLAAKEVEKEQEGGEKEEVEDLEASETPERVLMLAILGTGQESRERMDRALVTPWLRFLWEAYRTALETLKNNARLEIIYQQVAQMAFNFCLQHQRKTEFRRLCDLLRLHLTAASKYAHQPHAINLSDPETLQRHLDTRFVQLDAAIEMELWGEAFRSVEDVHHLLTLTSTVGVPGGAGAAKKPANLKQLSLYYEKLTRVFSPSAASTISSADTSLFHAAAYARYFATLRSLPSNGGKTTEELEHIAGGVVLSALCVREESLESKNSQGLTGGDVDSEDVKRGGRDFRLATLLGLNTLPTRRGMLKEAEQKGILSLCPEPIHQLHTLLTTPLSPHTLAKDSLPVLSQLAEPKFSTYAAYMPHLPQTLLTHLLLSLSETYSEIYLQSLWSMTAPWEGTQWGVSREAAEGWLMALCRRGVLKGRVDHGRGVVLFSEDEGENGDELRDVALRLQRALVFVEEPLKVEDHASPVYQALQAALAALPTTRAALIHKRALAQRRQELSAEMAARKTKEEQQSKLDHARAEKEEAEKREREAAKTKEQERVRREIESVRKGEQQKIVQDLIAKGNIKVNVDDIENLDTQKLVQLQVEQIEKQKKEVNDRLRIIAKRLDHTERAFRKEERPLLEEDYTRQQEEDRITFYQTQDETKKRLRHQFEEELSSKARLGRMMPDYLAMRSEIEGEKRKEFEARREVAERKRLEERRKRREEVLRAREEERKAVEEEERRIREEEERRIREEEEREREEEARLREEEEKAAAATVAKLKRSEEREREIAAARKRVEEEEARERAREERRRASHAAPPAVPAAAEPVAAWRRGGPRGTPSGTATPPREAPIPAAPLMSAGDRAPDGRRRLNLAPRTIPRPETPSAPSSPIPAPVPPAPTPERKGDTNVDDDGFTTVTREKAAVWSRGMGRRGRGGLGRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN1</accession>
    <name>M5FXN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628136.1">
        <property type="nucleotide sequence ID" value="XM_040772811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN1"/>
    <dbReference type="GeneID" id="63687873"/>
    <dbReference type="HOGENOM" id="CLU_1045927_0_0_1"/>
    <dbReference type="OrthoDB" id="10396334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067305" evidence="1">
        <location>
            <begin position="23"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="266" mass="28630" checksum="D93E1BEEEA26432B" modified="2013-05-29" version="1">MLAFAFLALLIALLPSFPLTAALPIPQLADIVGIGGEVPSRLIGSTVEGVLDDSLSPSLKQTTRSEIVARLLAEAEGGTTPQASAAARALTPRASPNVQVTANAKRSTPELVLNTPAVECEKALSVIDFEVVCAPVTVLDPVSAAAFLQKGGLVEYKDGTRYTDPLYSASSGEEGSPLRTMITAYAQLRPKGIERRAWPFFTRWAMQREREGSMLLALSPNTAIRIADLKEIGIHLLNQDQFDHVKVAGVTFDWRTMQAIVDNITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXY2</accession>
    <name>M5FXY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625304.1">
        <property type="nucleotide sequence ID" value="XM_040773691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXY2"/>
    <dbReference type="STRING" id="1858805.M5FXY2"/>
    <dbReference type="GeneID" id="63688753"/>
    <dbReference type="HOGENOM" id="CLU_045030_0_0_1"/>
    <dbReference type="OMA" id="PQTAWLN"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="49612" checksum="94326DA584FB1CB0" modified="2013-05-29" version="1">MSGTSRPNVLIVGGLTSVSRQFAQSLFPPNGPPLVEYLRIVDKYMVQPPTTYVGPDFPRLVNRPDVEYSQNNLTMPERLPTVFDPPSNGRPWDLVFDFLGEVVFDTSERTQILQTYRASVNCGIEAARRGTVKAYVRLTWGFYHCTWDRLHTEDEMLEPDGVRGLWWHETLRSLAAIPNLPLVIIRAGIPYGPYCSFGVVAQRILIGEIYRYKKRTMRYLWSPQLRLNTVHTDDISGACWKVAMWIATVGRNTAIAQAGVAMYFANDEERFPPGLPGVVPPDEAPRAAFFNLTDGSDSTQMSVGTAIASVFGISLGFRKVPSDADIEILAGTVNTWHGEVWWNLCQRNNPPIEYPPMHTYVEPHDLTDQASAWDGRKFNHIVRYTYKRPQLTAQAIAEIVSLWKREGSFPVVNAVDPSLSSDEEDDDDEEEHDDEDEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY00</accession>
    <name>M5FY00_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_16631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627557.1">
        <property type="nucleotide sequence ID" value="XM_040771214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY00"/>
    <dbReference type="GeneID" id="63686276"/>
    <dbReference type="HOGENOM" id="CLU_771657_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="39736" checksum="35C9B3ADAEA519AE" modified="2013-05-29" version="1">MSSTYTQQISLQSLSFCIVFNTMNFNNTGPLTLYCLKSEFMELWYTCEPQSKVVWSQRDLEEVIPLWGIVELVQEDEYDTWAEDIASEYEAWVKIKVTYPVVRDQDQKSTNADISVVVAEYHQAVPSSISPPIVPLESQVSSAGTLGTASNIHVNVQPDVEHITVELHDGIDEANPQNHCPCSPATSAIVVAATDVPLTINWILPLAEDTLVATSNIVNCTESHAALLIRHTAQLESVKDVLDVDLSDSDNKLCDTGIVDDVQETCDGTRSLPTNDSNVTLDAPVIPASGVHNLEGDVHMIFLNAVPDSEHDTLNYVNSQLRLMSGWQDHPDNDAYCWTRQEKIWNIIRYPDVPGNIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYG4</accession>
    <name>M5FYG4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628461.1">
        <property type="nucleotide sequence ID" value="XM_040768592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYG4"/>
    <dbReference type="STRING" id="1858805.M5FYG4"/>
    <dbReference type="GeneID" id="63683654"/>
    <dbReference type="HOGENOM" id="CLU_1704182_0_0_1"/>
    <dbReference type="OrthoDB" id="1750432at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17513" checksum="88A3F0815411B3F5" modified="2013-05-29" version="1">MDEGVYADDDKMSVIQNAKFPKDAQGMQCFLSMVTYLAPYFPDVAKYTGLLSLLTHQNRSYDVTPMHETCFKKILFLATDYLVLKPINPKNGIPIFVIVDASTSRFSDIINEQPQDEQAIVEVDMEDSIVDQLIKLKDLPKKEKKECVLQVQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYX1</accession>
    <name>M5FYX1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630135.1">
        <property type="nucleotide sequence ID" value="XM_040772418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYX1"/>
    <dbReference type="GeneID" id="63687480"/>
    <dbReference type="HOGENOM" id="CLU_1635329_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="162" mass="16753" checksum="D643456F9829A6D4" modified="2013-05-29" version="1">MFRLGTSRAPLLVFSAFLSTSPNPASRGNLIIAGLSAFLSTSPNPASRGDLLIAGLLASESPSLSLSFLSLSSRFFSLLSNSRFTPDSFSLGTSSSRSSRNPSIICTSTSISNPASRSKLASPCSGSSSSQQSSTTHTFSPTTSRAARAVATISAPELTPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYY3</accession>
    <name>M5FYY3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_106421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630150.1">
        <property type="nucleotide sequence ID" value="XM_040768266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYY3"/>
    <dbReference type="STRING" id="1858805.M5FYY3"/>
    <dbReference type="GeneID" id="63683328"/>
    <dbReference type="HOGENOM" id="CLU_052304_0_0_1"/>
    <dbReference type="OMA" id="AMGDLRF"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF2">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="144"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="447" mass="49163" checksum="D1AE8ECA711BA26A" modified="2013-05-29" version="1">MSSSVGRVAIIGTGSRGLMFLRGITERPGAQVVALCDVNSVRAAYYNDVLKSLGQAQAAIYHPDKFGEMVKAEKVDFVVITTVDQYHDLYVVPALEMGLRVLTEKPMTTTIEKCRRINETVARTGKHVTVTFNYRYNPTHELVKRTIAAGEIGRVISVHFEWLLDTVHGADYFKRWHAQKENSGGLMVHKSGHHFDLVNWWIDAMPVEVGGMGRLAFYGDQAGGSESGYVREYKRAAGSEQAKDDPFAIHIETDENLNRLYGKEAHAVDGYERDRNCFQPGITIEDDIGLLVRYDNGAVMSYHLTAYSPWEGYRVMFNGTKGRLELEVVESTHRLRQGPATSGGAVHGTSPLPNPGPSRVTLHPLWEPARELPIVAEHGSHGGGDKRMLNVLFGPRPGESVDEGDASKQAATERDGTAALAVGLAANESMTTGEFVKIKDLKLGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZQ3</accession>
    <name>M5FZQ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_22393</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628886.1">
        <property type="nucleotide sequence ID" value="XM_040772775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZQ3"/>
    <dbReference type="STRING" id="1858805.M5FZQ3"/>
    <dbReference type="GeneID" id="63687837"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_1"/>
    <dbReference type="OMA" id="AIRCEER"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067339" evidence="6">
        <location>
            <begin position="17"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="284" mass="30908" checksum="2069B94ACA497A83" modified="2013-05-29" version="1">MKVLIIGAGIAGPVLAMVLKHKGFEPVIYERYASVPAGGLALALSAQSFKVLNIIGLADEAVELGVQTDGFVQRSEITGQILQERSGRQPILRGQTGWPMTVTLRSKYCDFIVKKAEQRSIPIHWSKKLVDVKQDDDKVIAVFEDGTTDEGDLLVGCDGLHSKVRDALFGKTPAEYTGVVVIGGWTPYTNELHPTGQLTSLSVFGRGCHFFSSPTAEKYFWAVTMPAEAEMLEDWRMAGKLQIGDALASVPATTWSGDTGRIISGSDEVIRFGLYLRPIPPRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G049</accession>
    <name>M5G049_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628427.1">
        <property type="nucleotide sequence ID" value="XM_040772899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G049"/>
    <dbReference type="STRING" id="1858805.M5G049"/>
    <dbReference type="GeneID" id="63687961"/>
    <dbReference type="HOGENOM" id="CLU_496968_0_0_1"/>
    <dbReference type="OMA" id="WLADAYE"/>
    <dbReference type="OrthoDB" id="515064at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="60074" checksum="F8A6B21A5A1529A1" modified="2013-05-29" version="1">MWAESYAADLGLAPEFKTAIAHDIREQVQVMRKSLIISGHPLEGPVLDAELRTSFLPPLLPTYLTRNADEAMHFTPILSHLTEAEIAREEAEREKEARRRKRQTRGRRGVQQLPDREPLKTQRSIPLVGSMAPREQVPLVPVLTSRRAAAAAATANIAKDLPQPEQLERTGPAPPALVGPTLSLPPRKKSQKAVEEVAAAEAAATNSEGATAQKTPAERQRPATKKQLREKEREAKEMEYADTQKENVINGIWHCSNCGCPESIAVGRRKGPLGEKTMCGACGKYWHRYRRPREVEYNTSEEYHRNLRDAEEAAKRGTKYKKKPTALASLEAETPDIEMLEAPPVEEGVPEEVEAIPTLPTLETAPPAGTLTVEDASKPSHPSPAFADMPFGESSDEEFIVAVPRTPTKSSSTKPVSTDTAAPPETSPVLSSTKPPSPSKPKTTARIPKPKWLADAYEALMAKYPNDRIEIVPKANADPNAPAEWKVKCLDCPGKLYNTGPPKQNAPPPEPGKNPEETLSGFEVHLKNRNHRRGVETRLSGKPLVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0L2</accession>
    <name>M5G0L2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_80266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628562.1">
        <property type="nucleotide sequence ID" value="XM_040776435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0L2"/>
    <dbReference type="STRING" id="1858805.M5G0L2"/>
    <dbReference type="GeneID" id="63691497"/>
    <dbReference type="HOGENOM" id="CLU_029499_0_0_1"/>
    <dbReference type="OMA" id="GPNCWIC"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="9">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="10">
        <location>
            <begin position="256"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="364" mass="39831" checksum="EB11B66B802C96ED" modified="2013-05-29" version="1">MKALILVGGFGTRLRPLTLTLPKPLVEFANKPMILHQIEALVEAGVTDIVLAVNYRPEVMVKVLEKVEEQYNIKITFSVESEPLGTAGPLALARDILAKDDSPFFVLNADVTCAYPFKQLAEFHKSHGNEGTILVTKVAEPSKYGVIVSQPGSTKIDRFVEKPQTFVGNRINAGMYIFTPKILDRIELRPTSIEQEIFPAMAKAGELHTFELDGFWMDVGQPKDYLSGTCLYLTHLTSTKSKLLTYPEGNSYIYGGNVLIDPTAEVDPTALIGPNVVIGPGAKVGKGVRLQRCVLLANARVKDHAWVQSSILGWNSTIGKWSRVENITVLGDDVTIKDELYVNGASVLPHKSISSSIPSPTIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0M8</accession>
    <name>M5G0M8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cleavage/polyadenylation specificity factor A subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_17537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626284.1">
        <property type="nucleotide sequence ID" value="XM_040771292.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G0M8"/>
    <dbReference type="GeneID" id="63686354"/>
    <dbReference type="HOGENOM" id="CLU_002414_0_0_1"/>
    <dbReference type="OMA" id="GQVTQGW"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="116"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="627"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1267"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="834"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="834"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="876"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="956"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1620" mass="179755" checksum="00FAB265D377325E" modified="2013-05-29" version="1">MHAIRREIIPPSGISHAVSLQLIPPRKQRNSSKGRERTICQLVVARSSLLRVFDVKEEGDLREEATGDQVKLEDEEKLEDKEKLNGVNGDSKVNVTFQFRISRTYVNACFYASTSYFILATHSELTVSQAAVRTRLHLVREHRMHGFVTGLEKVRTLASGEDGMDRLLVSFKDAKIALLEWSDAIYDLSTVSLHTYERSSQVSTSEASEHRPLLRADPESRCAALLLPKDALAILPFVQRTGLDLADPARDKEREHQPYTPSYVFPLSDADDTLRHVLDFCFLPSFHTPTLAILYQPAQNWTGRLSQTKDNTSLAIVTLDLVGKGAAAGGGAGGGGAVISRTHGLPYDAFSLLPAREGSTFGGVVVLAGNSVLHVDPAGRIVGLAASGWHAQSSALRFPLWAFTAEEGETEERKLEGSRLCWAGEQQLILVGAQGWARELKVGVEGRNVSSLSAGRRLGRTSAPAVLCPVGEQSGRALKPTGRDLVWLASEAGQSVLLQVHKGEPRVEEVKPNGEEKEIEGEDMEIDADSDKNDDLADIYGDSGLPAAAASGVTAGPALPWLTLEVLDALQGHGQIADMSFALSFRSGPDRPTPKLVCSTPEGERGAWTVYENGLPIRVKRRVPAVAGTRGIWSLRVRRGDRARRGGRRERGEREWADGEERDNLIVSTDATPSPGISRTITVDSRGELQIISRLPALTLAAGVFFSHTCVMQVTPDSLHLLDGDGKELQVLKDNEGNKEASPIIKACVEDPWVVVTRENGSVALYLGDPGRRRLRYKGLPAHREKTATYAAAMIYTDYKDLLPAPHVEEPTINLRKRRASSLDAVEDALKEEEHISIEPESKRRRLRSSDEKVEEHDRREENGFGPGSGRSGRHSAREKERERVKEKERPHASRERERERSKDKDKDKDKERSRRDEKRDTKESSRRHRDSKDGREKDGKENGTSKDSRSHRHRESAEKESKEKERAGRRHESEKRKEVDQGPTVSQWLLLYNANGRLEIWSLPKMTLAFSTRLLSECRTVLDDAAAAAEPEEGADEMINIAPLQVEDVVLCPIGDDCVSLYLLVYYTEGRLAVYEATPRTATEADSTFQYRFTKVATHFADAEQHAAIRQMLPEARRLQLPSRRALIPFISDIKGGTSAVFQRGEEPCWIMASRQNGLQIIAYSSPLVYSFTPTSLFGNSGDFILYGEEGPVLMEFDEEPDTGRELSCRHIHSKRSYTSMAVDPGSNLVAAASSLKSFFLLYDDEEQPLWVPESTALFGPMAECSSLELVSPDTCQTLDGYDFAPNEFINVVKSVNLETLSSESGFKDYIAVGTSTFRGEDLAVRGATYIFEVIEVVSYPDDPLPPYRLKLLCRDEAKAPVNAICGLNGYLVSSQGFKVFVRAFEQDERLVGVAFMDAGVCVTSLTRLKNLLLIGDAKRSVSFVAFQEDPFKLRPTYVTDAAFLFDEGDFSILAADDEGTLRLFEFDPNLTGATHGNPLICETEFNGQSEHTHILAIAGRGREDPEEMQIPEAQLIFGTIDGTLGTISPVPDECFKRLQLLSGQLMRSVQHFAGLNPRAFRTVRNDLLSRPLNKGMLDYDLLHAFRELDIRRQATITKQIGTDTITILRDIRSLEEIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G116</accession>
    <name>M5G116_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626414.1">
        <property type="nucleotide sequence ID" value="XM_040770446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G116"/>
    <dbReference type="STRING" id="1858805.M5G116"/>
    <dbReference type="GeneID" id="63685508"/>
    <dbReference type="HOGENOM" id="CLU_313090_0_0_1"/>
    <dbReference type="OrthoDB" id="5590473at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="631"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="936" mass="99947" checksum="C9D1325E2EF3FA7C" modified="2013-05-29" version="1">MAPPPVPAQQFFQDQTHHHRAGSHTSSYSHHSHTSQQSQQSQRSQVSQQSQHSQVSQQSQHSQVSQVSKYTQGSAALSSTSSAPTLLSLSLSPPYSLTSSFDHSPSPATPSPAQQNGGLGDLSSVLSALQELHPGAARVREGETRTGTRAGTPRASPPRTGRRYGTPFPPSAQHDEDDLDDDEEEDEVDEEESSPPSPNSEAELSTVWSGPLKDIYLLPSERENSDDGDDTSDPSPVLNAFLPMPTPVPFEIARGRRVTPTGHATPLPGPFAPHFLQMHPSWAQAQVNEEWLHDPAASGGMSDDPPSSDPAELGDFESVLAYLHSQTRPLRELAHTSMYSSSTGVDTNMRTNSSTNYYPTSGYYPGPTQTYDFAAPPTTGAQNAGSDSDSKRRALLDDLVRYAGVGVVLQGARAGSILDETEPDDVEIDLELEGETLTGDSLHSQAYGGIGTVMPGVSAGAWAGTLWASNVGGLVGQTPKTPVKILLPSSAADHRPLPLPPTRAQPTPNAKNKTHQQPSAVTSKSKHTKDSLPAALVPLPSLAPPDRLAKLCQKLMIEFPLERGLLEMGMRETERFTRRWGTQLAIGEGEEELGQEGGEVHVFIDHSNILVGFLEWLKLNPPPPSHPSHPSHPSHASHTQTTPTTPSGKPKHMLSYPSLALLLERGRPITKRVLVASSPLYSSLEPIELCGYEVSVLQRVPQKARERVSQAASRAKGSSPGGPGGKGGKGNSPQGPKAVSVGGAATRRKGVITKPSAKQAAGDSSDTDLAPATPMRGSLAGIPVPTPQSGSASTSAGSRPPRFKEQAVDELLQLHIYKSILSHPSAPSHPGSPQQRNTLVIATGDAASSEFNEEGFVGCARAAVRMGWNVEVVGWANGGVGKGWWKLLEELRAEARAEKDDTRDADKHWVSAKKSGGIEDRLRVMGLEEWGWDLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1B2</accession>
    <name>M5G1B2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RhoGAP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_48619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1B2"/>
    <dbReference type="STRING" id="1858805.M5G1B2"/>
    <dbReference type="GeneID" id="63689916"/>
    <dbReference type="HOGENOM" id="CLU_005171_2_0_1"/>
    <dbReference type="OMA" id="DEMYNDC"/>
    <dbReference type="OrthoDB" id="437889at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45876">
        <property type="entry name" value="FI04035P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45876:SF8">
        <property type="entry name" value="FI04035P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="MyTH4" evidence="4">
        <location>
            <begin position="409"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="615"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="455"/>
            <end position="484"/>
        </location>
    </feature>
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        <location>
            <begin position="280"/>
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        </location>
    </feature>
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            <end position="333"/>
        </location>
    </feature>
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            <end position="363"/>
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    </feature>
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        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="815" mass="87994" checksum="685C8A5C0AD7B93C" modified="2013-05-29" version="1">MNASGPAASNWGANFWVTITDPQTQATFYACPATGAVSWDPPENTFLLPPSTEGEWWELKDESRGGLSYFYHTRTGETVWERPGGFVIPLGMIQQNSALGKRLSFVVEEPDQLDPTTEVDSTPSRSLSPTSSFGETIRPSTPTSPRHPSALQPRPSLPNITNLTAAAASIVSPLQAFPSDADGAKSLPASPLTAYGYPNGHGHGNGNAWPNGAGHHSQGSASSAPPPSVNGHPGHAVLVKKRTSGATNSLRTNGTLGTGTGSSSTPSSPSLPTAPPSPLFPRSASPRSSQVSLASLSPSFRGKPPSPLRPLPGAGGFSQRPGTAGSTKAQGMSVTVGPQGLGMREGPRQRSATLSSVRSSTHPTLPPTLQDDIKKFATSEYARKFFSQRSRGFWFLKRRKIPVDETMRWQRSALDGPLLVMNGSLHKDAVAAFKVVQRIMGDRDPLKPIGVGARMASQTGSRGSPNSSFSSVSGSTGPGGANGDGNSIIEEERWLLQAGISHTELRDEIYCQVMKQLTENPNTDSAFRGWQLLCVLIVTFPPSKYFEDHLTHFLHSSMHNTEGKVDVMAGYCLRRQEIIMWKGPRGKAPSLEEIEAAADAAFHPSVFGESLPLIMSLQATVYPPSEQPVPIILPFLSSGILALGGMKEEGIFRLPGDTDAVASLRLRIERGHYHLEGVEDPHVCASLMKSWLRELREPVIPEGQTYNLALQAAASDNPNQVLDVVRHLPEPNRRVLLHVISFLQLFVGDEVVEHTKMTEEGLARVMTPNLIRGRTDDLDVAFRNNHFENVFVGMLLRHMDCSTVDPGYRPMHGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G3</accession>
    <name>M5G2G3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_20949</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631300.1">
        <property type="nucleotide sequence ID" value="XM_040772159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G3"/>
    <dbReference type="STRING" id="1858805.M5G2G3"/>
    <dbReference type="GeneID" id="63687221"/>
    <dbReference type="HOGENOM" id="CLU_065898_0_2_1"/>
    <dbReference type="OMA" id="PYEEWSD"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="89"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="269" mass="28854" checksum="23ED4B4C5528D5FE" modified="2013-05-29" version="1">MADRGTGTGAGGEGRGRGGFGRGGRGRGGPRGRGGRGRGGRKDEEKEWAPVTKLGRLVKDGKIKSIEEIYLYSLPIKEYQIVDIFLPRLKDEVMKIMPVQKQTRAGQRTRFKAFVAIGDSDGHVGLGVKCAKEVATAIRGAIILAKLSVVPVRRGYWGAHLGEPHTVPSKVSGKVGSVMCRLIPAPRGTGIVAAPASKRLLQLAGVQDVYTQSKGSTATMGNFLKATFAAITKTYAFVTPDLWPESQLTKTPFDMHSAHLQLTAKRVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2L0</accession>
    <name>M5G2L0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1746 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631355.1">
        <property type="nucleotide sequence ID" value="XM_040772181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2L0"/>
    <dbReference type="STRING" id="1858805.M5G2L0"/>
    <dbReference type="GeneID" id="63687243"/>
    <dbReference type="HOGENOM" id="CLU_1610700_0_0_1"/>
    <dbReference type="OrthoDB" id="10418001at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013715">
        <property type="entry name" value="DUF1746"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08508">
        <property type="entry name" value="DUF1746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1746" evidence="2">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="165" mass="19324" checksum="9475966E7F07D7F6" modified="2013-05-29" version="1">MSLLLFISRSFFHLHCVNLREWHPGRSLRFFVGLLIFNFGHALLRHSWGKLSKTFILDFVGHSSRASRFHFLLLDLLILVLQVITVYLTWETGHRDLQVPDPLESSEFVEDAEDFLDLEAAEIPKIKHPALRPVFTLRYRHCWQRLWEPHNNTFVVTSGSNAETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2X1</accession>
    <name>M5G2X1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_91125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="1858805.M5G2X1"/>
    <dbReference type="GeneID" id="63692057"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:glucan catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="ConA-like_dom_sf"/>
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        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
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        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
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    <dbReference type="PANTHER" id="PTHR10963">
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            <end position="292"/>
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            <end position="274"/>
        </location>
    </feature>
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        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="292" mass="31001" checksum="99A1ED1E1C02DB12" modified="2013-05-29" version="1">MISKVSALLLGLAGSAVATTYNIADTYIGSQFLSRFTCKRLLTRLTVASTTSQATALANNLTYASGNTFIMRADYTTTLTSSGPGRNSVRIQSNNTYTYALMVLDLSHMPEGCGTWPAFWTTGATNWPTCGEIDIIEGVNNEMVTNFTCLMDISGGTSASTDCNANDNGNQGCGVHSSFSNSFGPPFNANGGGVYAMERTTTSISVWFWPTNSGLAPSAVLSGASSLDTSTFGEPDALFVNTDCDIPSHFTAHNIIFDLTFCGDWAGNAYPSTCPSDCNDYVDNNPFAFENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G333</accession>
    <name>M5G333_DACPD</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_115366</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G333"/>
    <dbReference type="GeneID" id="63685052"/>
    <dbReference type="HOGENOM" id="CLU_918352_0_0_1"/>
    <dbReference type="OrthoDB" id="3249298at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="303" mass="34595" checksum="F436B2AC36E5273C" modified="2013-05-29" version="1">MSLSWDLRETLFRCLRKIQTSLCSVWGAIMLCIRRWMNSTLGFLTEPTSSPLLRPRVIGCMSSTPLFRCLAPGSVAAQRSASTMVSPRQPVSCNSWMSSSQPNLDTSSIRTRSTCPALYLGVWHRSNSVPFVTADSRQQKQTTRRAMVRLMFAVNQEVGPRVLQLLGARYPDVARERQEIIEHTWTHPNLWDKPDLAGCHHYLWQVAWTTLAVRCGSGNVVHINVKDDLHQFTVLFTYGSYTMGYFIIPQLNICIPLQPGQLLFVKTCYLVHYVSHFEGVSYVFTGFMDGQLCNDYWAWRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Q1</accession>
    <name>M5G3Q1_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_99808</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040777628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Q1"/>
    <dbReference type="GeneID" id="63692690"/>
    <dbReference type="HOGENOM" id="CLU_1767988_0_0_1"/>
    <dbReference type="OrthoDB" id="10427769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067558" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="16590" checksum="C8E5723EEF6A3977" modified="2013-05-29" version="1">MPSFCKVAVVLGLLAPAFAAGAIEPRKQDYEIKPVHQTSFFPHEQEGRLGHHPINGHKHANHHHSLEHRIKKMERELESLRQTVFDMEHFFASFSHVVSVEGHKHGPTIITTNMVTSMLSCTTMSMKRRTNLITSTNINTAMQIAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3U8</accession>
    <name>M5G3U8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heme oxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630243.1">
        <property type="nucleotide sequence ID" value="XM_040772438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3U8"/>
    <dbReference type="STRING" id="1858805.M5G3U8"/>
    <dbReference type="GeneID" id="63687500"/>
    <dbReference type="HOGENOM" id="CLU_057050_1_0_1"/>
    <dbReference type="OrthoDB" id="652091at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="291" mass="31971" checksum="02E0C4EC97798D45" modified="2013-05-29" version="1">MYVTDSDFRANSALESGLSLNSNNTVLGPTYHPSLLSRAPPLEADISFLLGTPEWKSHPIPASLLRSPPKPLQEYVERLKRVSEETPERLLAHAYVRYLGDLSGGQIIKRRLARKLSLASDSSAGNEDGPIPGLAFFSFPPLFVGAGQADLSEMQKIKQWFRAGMDEGVGNDETLKRALVEEANLAFDLNAGLFRMVDEDTTSANEKREPAVIEEVYSPLSKLSSGKQDVKAESGQKGYSLASFVAFLVAVGLAHFLIVTLGLTGQRGWEKWEIIRDWVMNAMNVSGRCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G407</accession>
    <name>M5G407_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629839.1">
        <property type="nucleotide sequence ID" value="XM_040769963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G407"/>
    <dbReference type="STRING" id="1858805.M5G407"/>
    <dbReference type="GeneID" id="63685025"/>
    <dbReference type="HOGENOM" id="CLU_001665_0_0_1"/>
    <dbReference type="OMA" id="KELWRIM"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049916">
        <property type="entry name" value="WDR72-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099:SF4">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="745" mass="80872" checksum="B8E456C19801ED07" modified="2013-05-29" version="1">MSPTPELAEEGEPPRPTCLLRQDWDSLVLGFADGTIARTSLKDLLSQGINGRLRTSGTRRLYGEVTFIRVLQLEGGKEIIVAGSDDGGVGVWNSPDLNLLLKKILFASPLVRAELVHGYAGMQEGLVLVSGEGTIAFVDCTDSLTFTSLIPCASSPLIKACLSTDTLIILYANNRARLWDVRSKELWRIMEGDKAKEMIDQGGWGIVDAEERGVDVSPVPLFDVPCAPVALDAGISALLAAQNLGVNPPLDKQYPDNLPKQLHTILPVVAASFTYGLDQSVDGLCDDQKPIGAGSVALPSASFSGPVKASEENAVWQVSPTATTFLLLSLITVLRICLPSEVFEMHATAIIAFYVSSLPETMPAYQSPSLDVLVRFWYDPSSEIQHGARLLFNAVVSQMADSEVISIAELWQRQLPCVQPDASQNSAACARALLIAGTLAAERYSLLSTSTLRDISKSISLFLHAETCPYSVLAIDLCSRGFHIWQQYIDAVETLRCLFRRAVTFEKSTLPTVGHQARLAILHIASTSTALFMTTVSLDIVNAPTAEHLKSIMLVIAFIVKKKPLVLYPSLPKLVDAVVKSLDPNSSSRDAVLQAATIILDQLVHTYPSVAFNAKVQRLAVGTIEGAVIMYDLKTATRLYVLEAHRKRVSACSFSPDGRRLVSMSLEESVVMVWKVGTSFSSLFNPGGPPRQGHAGSDPYKTIPFSAGEEGHITVAATLEWVTFEWPGDRTARLKIRDSTFTFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G430</accession>
    <name>M5G430_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630328.1">
        <property type="nucleotide sequence ID" value="XM_040772196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G430"/>
    <dbReference type="GeneID" id="63687258"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OMA" id="IRAPIDM"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="425"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="460" mass="49606" checksum="90BDEE756314E87E" modified="2013-05-29" version="1">MDSQMTLSNGSAGGTHEKTRPSGEGSLELPTPSSIEAVVQGQEKPADRASAPTLPHHTYPEGGLRGWLTVAGAWLCLVCTFGYTNAYGVYQSYYVQTMLPSSSTSAISWIGSLQLFFLFAMGLPTGRLFDAGYFRHLMIGGMVIMVGSLFAQSAAQHDQYYQVFLSQAVGQGIGGGMLYLPAISIISHYFQKRRALAIGVVQSGSSTGGIVFPILLSNLFVEVGYVWAVRITGFIMLGLLLAANLLASPRLAPKKDHPKPDLRRFFTDPPYITAVLGMVLVWWGLFYPFFYIQLFASSHGLSDNYAFYTIAIINAASMIGRTLPNVFADKTGIMPLLVPSTAVSAILLLILIACTNMAGVTVFCVLFGLFSGAFISLMAPMFAIMSDHVFEIGIRFGFSIFIMAFAGLTGTPITGALVGNSPPYIWYRPCVFAGVCMLGGTGLLTFSWLALGRKQGHLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4H3</accession>
    <name>M5G4H3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_46332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G4H3"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:transcription regulator complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000303">
        <property type="entry name" value="Zinc finger protein 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="95" mass="10463" checksum="446C805D7522B9A3" modified="2013-05-29" version="1">MELSSILNPETEAERHGYSAERADDPEGPPPPRGSGGHGTPSVGRKYPCKVCQRVFSTSGHLSRHMKVHTGERKYVCPFPGCNVKCNRSDNLLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4R3</accession>
    <name>M5G4R3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630099.1">
        <property type="nucleotide sequence ID" value="XM_040774976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4R3"/>
    <dbReference type="STRING" id="1858805.M5G4R3"/>
    <dbReference type="GeneID" id="63690038"/>
    <dbReference type="HOGENOM" id="CLU_091791_0_0_1"/>
    <dbReference type="OMA" id="FWHASEY"/>
    <dbReference type="OrthoDB" id="3251205at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="16902" checksum="8C82C96298FF5E59" modified="2013-05-29" version="1" fragment="single">FLASCRHAFILISTDMIQLGKLAKYSLVCLKKILSMLGQDLAMGYDIGCNHSKTITNSTLDPMAHSQALQVFVGAFHGYAHNWQCQLQYHPQFITSAGLKVFETNKWIFSKQNLTALLFWHASEYHRHVTLHCFWVRWDEDQQAGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4X6</accession>
    <name>M5G4X6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630593.1">
        <property type="nucleotide sequence ID" value="XM_040768155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4X6"/>
    <dbReference type="STRING" id="1858805.M5G4X6"/>
    <dbReference type="GeneID" id="63683217"/>
    <dbReference type="HOGENOM" id="CLU_026509_0_0_1"/>
    <dbReference type="OrthoDB" id="7700931at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF125">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YLR001C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="115"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="348"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="610" mass="67686" checksum="217E0C1D63B94E0F" modified="2013-05-29" version="1">MLFERYFYLEQEGSGCAHSPSLGKPRRLLNPTRGSSVVAVTLASSALALVTPEPREPQLSILPVDGCESLLSQGIANLWEGLEEQLKWVEHLWSSDEIEIVCEEQLEKEDEEPRKKTAYEILSKDDKFSKFFFLVTHDPLSVAYLSRESGNFTLFAPTNAAFPAPSPHEFLLEFGNPLALETLHRYFSHNPNGRGWEHLAAVRILHALLQYHIIPKSAHPIFELAEFSTVATGLTVPGALLGAAQRINLSPALRPLPTIQLNFAGHIVAADLHASNGIVHGVSSALQPGLSAMDELYAVPWLFPFTRQQAPWVLGITASALEKTGLNKVVDHKPVFHRPGPFAVPAAHEDVQDGIDAAEEMWLNITAESLAPIPLPGLSWEGSPAVTVFAPTNKAWSLLPPRLSKWFHSPWGEFALDKLLKYHVINGTVLFADYVHPPIVPSLLRARDGIGPRPDFEDCGPADPVQDWTDWTVAIPTESSEETNMWPTYDYLLFLPTLLGKNFTLPVRISKDPLFPLPPPGQGREVAVYRMWAQGVPVAIRDVPVRNGVIQAVERVLNPLAGNHKEKRCHMGGVQEGGEAVEKQEVEDEWEGWEEWFVKWAMEALDEALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G511</accession>
    <name>M5G511_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630204.1">
        <property type="nucleotide sequence ID" value="XM_040772431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G511"/>
    <dbReference type="GeneID" id="63687493"/>
    <dbReference type="HOGENOM" id="CLU_2440804_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="10640" checksum="407894E4C5A18E89" modified="2013-05-29" version="1">MLPFFTEYLYFPRLAKCIITKSTLFEVNAQCQHVLFTPNDKFLYGQSPQQRKHAVYLARTQEEQLAYQCKQTKKNVEAMSREEEQVPSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5A8</accession>
    <name>M5G5A8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">DNA replication licensing factor mcm2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_49728</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630753.1">
        <property type="nucleotide sequence ID" value="XM_040774932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5A8"/>
    <dbReference type="STRING" id="1858805.M5G5A8"/>
    <dbReference type="GeneID" id="63689994"/>
    <dbReference type="HOGENOM" id="CLU_000995_0_1_1"/>
    <dbReference type="OMA" id="TYERVTT"/>
    <dbReference type="OrthoDB" id="844at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17753">
        <property type="entry name" value="MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059098">
        <property type="entry name" value="WHD_MCM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23669">
        <property type="entry name" value="WHD_MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="18">
        <location>
            <begin position="366"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="782"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="796"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00074927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU03859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="827" mass="93236" checksum="536D189BE1165F7C" modified="2013-05-29" version="1">MNRRDRAERGLARRPRRAPGFLPSDDEDEEDRGPLEGMVRRTRRQYDERRMMDDAEGVDDTIPLEDLGDIKADTIAEWVSLPNVGKAVTQQFRAFLTGHTDGGMESVYGAKITRLAEQNLESLEVSFKDLADYKPILAYFLANCPAPMLAYFDEVAMQSVLAFYPAYERIHAELHVRITDLPTSCTLRDLRQSNLNCLVRVSGVVTRRSGVFPQLKYVKFDCKKCGETLGPFYQDASKEIKISYCPNCEGRGPFTINTEQTVYRNYQKMTLQESPGSVPAGRLPRHREVILLWDLIDSAKPGEEIEVTGIYRNNFDASLNARNGFPVFSTVIEANHINKKEDLFAAFRLTEEDERKIVQLSRDPRIRKRIIKSIAPSIFGHDDIKAAIALSLFSGVPKDVKGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAYRAVFTTGQGASAVGLTASVRKDPATREWTLEGGALVLADKGVCLIDEFDKMNDSDRTSIHEAMEQQSISLSKAGIVTTLQARCAIVAAANPIRGRYNPTIPFQQNVELTEPIISRFDVLCVVKDTVDPVKDELLAKFVVDSHIRSHPTFKAAAAEDEMDGADNAGIIPQDMLRKYIMYAKERVKPKLQDMDQEKLARLYADLRRESVATGSMPITVRHLESCIRMAEASAKMQLREYVRADDIDLSIQVSVGSFVECQKMSVKKTLERMFRKYVHRARDHEELLHFLLGNLIKEKVRIYQAAHHTAPTSVSVKISELEDSAREHEIYDVQAYLHSAVFRANGYEMGKSREKNGTEHPAVVKHFVDPEHREQGRREGSRAPSDGDYVFVEQGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J7</accession>
    <name>M5G5J7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630389.1">
        <property type="nucleotide sequence ID" value="XM_040768126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5J7"/>
    <dbReference type="GeneID" id="63683188"/>
    <dbReference type="HOGENOM" id="CLU_037757_0_0_1"/>
    <dbReference type="OMA" id="PAREVNN"/>
    <dbReference type="OrthoDB" id="2564465at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="399" mass="41332" checksum="ACFA54FAE4B2AACD" modified="2013-05-29" version="1">MGSSQSSLIITAAVAIVGLGLAYVFLRPAPPPPPSLKRGSSTIAPSASSKKGKKKKKASPAAASSSAPGKVEEKRLPGALVEDSEATSTTVPDEPAPTPGAGKKKKKSKSASSSHAAGAPVTSGGTRVPPVPQRTAGPSTSAADPDGPWTRVETRRSARTANHASGIAGIAAGTGGSDRHVEGSIGDITTSVTEEDSGIGEVGEAAEGEEGESEKGPSGVMRSTVERMLPRPRKTAVDDMLETPAQSVSRVMRVKPSAEERPAAGFSWADYEDVEDSAGGAGAEEADDEGEWGIVKSRNRRATSHNGFASSSGSTPASRPAKASETLTKKQRQNARKREADKSLRSDQEAERLALLARHKRELENERMKEQARGSGGANKKLSGGMRASVNEKGALVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5M9</accession>
    <name>M5G5M9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_20008</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632460.1">
        <property type="nucleotide sequence ID" value="XM_040771760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5M9"/>
    <dbReference type="STRING" id="1858805.M5G5M9"/>
    <dbReference type="GeneID" id="63686822"/>
    <dbReference type="HOGENOM" id="CLU_448347_0_0_1"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF488">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="416"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="168"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="67422" checksum="9AC910C09C14771E" modified="2013-05-29" version="1">MSSTSRKVIDPTFLYRPPSITVSRSDRPIPMSTLGRHPSGRSAHSSRSGASGLHSSRRRERAYENNLPGYQSDGYLSDGPRSGYGSDGPRSGYGSDGPRSGYGSDGPRGYVSDTGRIKRMLPIGPDRSMAVHHPSLSRRHEPDLPLAGDRRSWDNRWAEHVETMAIGRGAGERRRSTRLTDTEEEKNIGFGMIVPEDVTPPDEPSSPQEPARSQYGSERRYGGSVRDSPNVRTIESLQDEEMTTQSGQTSAKRPHFAPLPPPASKSQKVTFSYGDTGDKTHIPLAHKATGPRNYEGYPSRNSFYFRGHILTGGDNPWPFIASLNLCLVVAGIWLAGVGRNCGSVWGNRGWAILAVGCYGIALVLTSMLVTAFRDPGIVPRDLDPDPPYSTSSVVDGEEPIPLPRDLRARSGIVRVKYCSTCKTYRPPRASHCKVCDNCVDGIDHHCTYLHNCVGRRNYTTFMTFLMSAVLTLCYVIVTSALELYSLSFTYDGFASALRAEPLAGVSFALGIIVIWPMSALLAYHIRLQVLNITTVEQVRAQAHRSMIPGPAPPNAFNLGHWYMNVGTVLCRPGGFSWIEPWERKTEDMRQVNPGWRQDEFDERQWGMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G604</accession>
    <name>M5G604_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21167</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630544.1">
        <property type="nucleotide sequence ID" value="XM_040772268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G604"/>
    <dbReference type="STRING" id="1858805.M5G604"/>
    <dbReference type="GeneID" id="63687330"/>
    <dbReference type="HOGENOM" id="CLU_097347_1_0_1"/>
    <dbReference type="OMA" id="KTHCRDM"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="17483" checksum="DA1B0F338B5EC709" modified="2013-05-29" version="1">MADFEATDPAVAAELKKRRTFRTFSFRGIELEKLLDLSNEDFVEIVHARARRRFQRGLKRKPMGLIKKLRKAKKEAPPNEKPAVVKTHLRDMIVVPEMIGSVVGIYNGKVFNAVEIKPEMTGHYLGEFSISYKPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G669</accession>
    <name>M5G669_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_49622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630589.1">
        <property type="nucleotide sequence ID" value="XM_040774918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G669"/>
    <dbReference type="STRING" id="1858805.M5G669"/>
    <dbReference type="GeneID" id="63689980"/>
    <dbReference type="HOGENOM" id="CLU_195467_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8955" checksum="5EBD77ADA9AA9434" modified="2013-05-29" version="1">MSWCPDRTAVYIAPPNLWFTIMPNDLHDPLAQVFAGEDINMNHFMNTVGPSSSKRAQNIMQDPYTAAKFFQYITRSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6G4</accession>
    <name>M5G6G4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000030653">
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        <location>
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            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
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            <end position="138"/>
        </location>
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            <end position="331"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU04284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="416" mass="45505" checksum="56209FEFA34B0382" modified="2013-05-29" version="1">MLSARPPNVLQERTDFNLRAFASKTPGRPGTQNIGGLKSAIRKENALRAPMTTLARSKATINLLDESIEPKRLFKDFPGKLPAGNGLSDVTNKTPALNRRQPLGFKTPLPGTSKLLKLAPLLSTSIESAPAAEAAPTPLREPPPSALRPSSSRRTSRIIRSASKSFETPAPSTRKPHWDVNEDEISVGSLEDVEIKEDVNEDDESEIEYMPPTAWIEPYEAPLPLPDYKALCPKLWEIARMPGFGDPNEDVFDDSFLETWVPAECPPEDLQIPLRPLQEEEFFGPPLQAPKAVFARNTAVSRIAKSPATRDMSRNTTRPSVPRSQATSTLSRPLPRPVPVKPASRPQSLALNPSTRTGIAQRPSILAKPAAVKGLTTSKPLRATETPKAPKPTDTLEVFMAPPDFTALDDGFRFDV</sequence>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
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                <person name="Hori C."/>
                <person name="Igarashi K."/>
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                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
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                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
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                <person name="Sabat G."/>
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                <person name="Young D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="14605" checksum="0938B5C190E15EEF" modified="2013-05-29" version="1">MPTHMLTLGKDPAITYAFMDQLAAARPGMYTASTAHSPDEFETYAKNGKNDIDFVLLGAAQTDDQVINAKRIVANVWGSVKETLRQVLSDGGTFNTVVSVYDHTRSVQHSLMWSMWIVTPGRPTTAFLGANVR</sequence>
</entry>
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    <accession>M5G7D6</accession>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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        <property type="entry name" value="Ubiquitin-like_domsf"/>
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    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
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    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067610" description="UBX domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="4">
        <location>
            <begin position="315"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="429" mass="48493" checksum="511E6AA59AE3D85A" modified="2013-05-29" version="1">MSIGLLSNLLQFVLRLLGIPIPRFLRASSATYTSLRGPPPIDDPMVAADRLVRQLEEETGAVCVSRVGMSLQQGEIEATGSGPDGSEKRKVLPDFWIGSYKSALEMAKKDIRILCVVLMSEEHQDMQEFRRSVLTDPDLVRVLTDHAIMTWAGDIRDREAYEVAQSLQATTYPFVAFIALQTRGSRSNANSSSSGATRLAVLSRHEGSPLSTTSAPVLQAYIISTLIPRITPLLTRLRNEQRARQAERLLREEQDRAFREAEKKDRERIEKRRAEEQVRLEAEREKRQQAQEASLLVERRDQWRRWARTALVPPESLDGVRIGIRLPDGRRLVRNFNEDSTLEQLYAYVDVQSIPIESPARLHLGSSPPDFIPEWNFRLASTYPRIEIPFVKDARISDVPALQNGANLIAELIRNGISTAEEDTDSEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Y2</accession>
    <name>M5G7Y2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_114191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631763.1">
        <property type="nucleotide sequence ID" value="XM_040769775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Y2"/>
    <dbReference type="STRING" id="1858805.M5G7Y2"/>
    <dbReference type="GeneID" id="63684837"/>
    <dbReference type="HOGENOM" id="CLU_523754_0_0_1"/>
    <dbReference type="OMA" id="QGICETE"/>
    <dbReference type="OrthoDB" id="26136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="438"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="57470" checksum="14682635D5D4213C" modified="2013-05-29" version="1">MFLWRRAFPHSSSSSSSTPLPSSKPKPTPAPPAAAAAASLPPTPTAQIPPLPDPWRKRILIMGLRRSGKTTAREVVFHRLPLNRAFFVDTTLDVVKEDVECVHLPLPAYNFSHVLLFLLLVTVLVLALALAFHRFWIPLQLWEIPGSQSLDILPLHSSHLSHFSSLIWFIDAADDYTESLRSLLRVLGTVSLHNPGLHVDVFAHKSDAWDEFYRQDAFRQIQERTLTELEDHPSPGVQEMAGRVQFHLTSVYDHSVFEAMSRVVQRLVPTLAFLEQTLNYWSQTLDIPKCFLFDVPSRLYITTDASPVDAASHDVCCQYIENIEAFAGLFACVCLPPPSLPLSPSQFYPFPIPYSRTPNPLPRNISRPSPPNPQETPTYLASCSAKIAQENTVAYWQISKRLAIVALVQTQMYDTHRGAIEMNVKSLREALLRLEAHEERKRRPPPPAPAVPPPAVPPTAVSPPAPAPAELAPAPGIEPGIDGTHPSPAMGKPGTGSSKSENSSLRTPSVHLPERGKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F7</accession>
    <name>M5G8F7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_51403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629034.1">
        <property type="nucleotide sequence ID" value="XM_040775039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F7"/>
    <dbReference type="GeneID" id="63690101"/>
    <dbReference type="HOGENOM" id="CLU_033465_3_0_1"/>
    <dbReference type="OMA" id="YSIPCAN"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="392" mass="43342" checksum="271C26B246B8B072" modified="2013-05-29" version="1">MSATVPGILTTPTVVTFVIPGIETLTTTLPSGYNYESATSAFASLTSKLAAAATATATSSNSHRLANSVWPYVPSFPVALIAVILYALVTALLIARMFQYKAWWFVALILGGIMETLGFGARARNTQDLNNESLYKMQLCCTILAPIFTAAAEYILLGRIMGYVGRRFSLLRPGLISWIFIISDAVSFLIQVGGAAALLARPDLNSQSTPSQIQRAQNLLNLGDNVLLAGLAVNLASFVIFVLQVRSYSIPCANTHPRQVTYFDYKTRTQCAITGPWRTLLYALYVSTVLVLIRQVYRVIEFSQGWFGFLPTHEGYFYGLDSLVILLASAVYIWYWPDKYIPGDRHMRLGENGTEWREMTKRERKAQALEEAGRKASSGEVSVREVKDGDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G914</accession>
    <name>M5G914_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_34470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627170.1">
        <property type="nucleotide sequence ID" value="XM_040774380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G914"/>
    <dbReference type="STRING" id="1858805.M5G914"/>
    <dbReference type="GeneID" id="63689442"/>
    <dbReference type="HOGENOM" id="CLU_136924_1_0_1"/>
    <dbReference type="OrthoDB" id="446925at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="75" mass="8457" checksum="211BC19FB7EA6C6E" modified="2013-05-29" version="1" fragment="single">SKWPKVVPAVFWAQQICIHSATGMSPFYMTLGIHPLLLMDIIEATWLAPPLDQLLSHADLVAFCTQQLLKRPEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G954</accession>
    <name>M5G954_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_47945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631604.1">
        <property type="nucleotide sequence ID" value="XM_040774795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G954"/>
    <dbReference type="GeneID" id="63689857"/>
    <dbReference type="HOGENOM" id="CLU_160852_0_0_1"/>
    <dbReference type="OMA" id="RSSHCIG"/>
    <dbReference type="OrthoDB" id="1044435at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="4">
        <location>
            <begin position="10"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="110" mass="12524" checksum="EB56E951BF7B4FB7" modified="2013-05-29" version="1">MNKDSGDNAFFYGTLMYPKIIKRVLNNTGNHLSVCPAILLDYTRHQVKHADYPGVIPYSQTRRLLDRELPESERCVRGSLVYGLTKEDFSVLDIFEGGVRPLELIPILLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9D6</accession>
    <name>M5G9D6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631734.1">
        <property type="nucleotide sequence ID" value="XM_040771935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9D6"/>
    <dbReference type="GeneID" id="63686997"/>
    <dbReference type="HOGENOM" id="CLU_023462_0_0_1"/>
    <dbReference type="OMA" id="LMFNGYC"/>
    <dbReference type="OrthoDB" id="3269821at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="650" mass="70870" checksum="149E828E9D5BBDE5" modified="2013-05-29" version="1">MGQTPSSSPRERRRSRVTSDLSFYLALPSLSDLLSKPRILLRLLANGLVLGDIVALMQTCRKTREALTHDGEIREIIFERTIPGYRRKISDYTLDEDVSATMVDYELLGESLAMPLHRYPTHALQILTSPPSAIPSVEAQQITQYLEALTQVHSRFVLLLRSRGPRWSLQLELDDPSWLVSNGGGGANALGQGRQNAHLWHRGPPREIVFPTPLWGGDDDNSPPSPLTIRSTPPSVPKRSTTKRRSSVLVNLRRSNSRAPPPPPNPVPAALSYYRQPQLIVPPNRRASFSRSLDSFVGGPTFPGLPPFGHSPSNNLTYPHGSAPPAVVSSQTWPRSTPSPPLISPSPPSPTGSGSPSGSDYSPPSLSHVTLPPMQPHSQFWGSHGLPPITSPHDLHLACLPTRAAVIRVFVPCASLSPSALLACEGQLFASGLWHFLHPGDVVCNLGYIPHAGSKSTSPQSSSAEIPVDPMQGDEDAPRGWLLYTGTSLVPYYPPAPPPLKNPLSLPTPTYYTHLSTTAPRFLLTLPGKPIDRPTLQASIMTLPPPHLGANVKIQVWRARITVPGDMIVYPNDSMQGTYIGPGWAGEWVVEADGTKEGLSALMDAEEGGERVWEVVKGRSRPGRVWLRLISTPSPPRSEEKPQELMQRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9M9</accession>
    <name>M5G9M9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629466.1">
        <property type="nucleotide sequence ID" value="XM_040770042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9M9"/>
    <dbReference type="GeneID" id="63685104"/>
    <dbReference type="HOGENOM" id="CLU_1008392_0_0_1"/>
    <dbReference type="OrthoDB" id="10432488at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="165"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="276" mass="31134" checksum="485A4D75FD190FA4" modified="2013-05-29" version="1">MLSVMTLPVPYSFNMDIFDGQANSLTVPRIHPPSFPPWDIDAQAQTLSEPVSALSGISAESWLSNSVSVDYTTMNYDSTGTAYQYGQAYDRPWLFSPPSGFRKGLKKTDLRPVHAPTKARSQLPRAAKRSSPYARPEESGPSRRRGSDSGGSVHSANSSPCPEQLAKLEKRRRANAEAQRLSRQRKEETLSTLREEIDRLSRRTATLDEDLQRLRQTKSEVNRILQDETAKVGHLQMEIDSRRRRQVQGDFMQLQAEQGMTPMIGLTSFPDSFWTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA19</accession>
    <name>M5GA19_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23057</name>
        <name evidence="2" type="ORF">DACRYDRAFT_23066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627569.1">
        <property type="nucleotide sequence ID" value="XM_040773073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA19"/>
    <dbReference type="GeneID" id="63688135"/>
    <dbReference type="HOGENOM" id="CLU_2497854_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9720" checksum="4D58B4B7C1F45377" modified="2013-05-29" version="1">MADRGKLGELNETRSGCCLLIRLWSKIAHDTRKAVEVERVERFAIAKTSSRCQLELVEDHLIAIENAGPHYSLAWTGSQYPTFIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC8</accession>
    <name>M5GAC8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_15483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629796.1">
        <property type="nucleotide sequence ID" value="XM_040771109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC8"/>
    <dbReference type="STRING" id="1858805.M5GAC8"/>
    <dbReference type="GeneID" id="63686171"/>
    <dbReference type="HOGENOM" id="CLU_369187_0_0_1"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="754" mass="85014" checksum="8BA08D9916D7A026" modified="2013-05-29" version="1">MPPLPRNHEQIEELTASLERLQESWDQVTDALMEKEKELKKASAELDETLLFCQELQNSLRDVEFAKVLAQQEVERLLNKKSSLCAGQKQLEERVKKSEARELSGSRTMRRLTAKSQREASQYEEAIRLLTRDARRLQAEINERDTRSAADLEDAVAKFNTERMILMGENNELREVLKRVQEDNEELRRALIESTVCAPSINPLPVLLSTANKGENLSTVGVMQALDAGDRAQTELNNDSKAAELSAGLGKMSQREPRQQPTGSELTAIPPLMFTRSRTHQQLSRPKHTWTTRRRRFKEHVFYTQRSSLSTQGGALAPEQTSEDLGPLIRLRRPMSCPDRDDTPITDSRDDEHQAVCLSIPELVSVAASNLANAETGDSRKSISLENQTVSNNGPAVFSVIAQQKRSSTTNSDLVPARGSTGPRKGREIPEWEGQRHAWKTAREGRPIGEVRAAKSAYERKRQLFRRRRRVAKEHAVLTLLDTMGIQGMSSDKESESGCLRAKKRPEYSEACDRLRFYLDERVVKYLWFKERGGRNGGDLAILTTSGYPQDVVRRLRSVSDSSRGSEREFATLCLGLEPILYQALRSQPLSLPIRPSCSRTRAFPPGTEEVSRENHEHSLGSAGEDVWTFMRKIISKTKPMRAMTALALYYVYKLKHEPIADSSPQDTAMLALIALMLANKCWDDNTYTNRAWSECSGMSLEDINRAEREFLNGIGYNISVNRPTYDAWVKTLISLSLARSREDTASAIHPDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAJ3</accession>
    <name>M5GAJ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632269.1">
        <property type="nucleotide sequence ID" value="XM_040769641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAJ3"/>
    <dbReference type="GeneID" id="63684703"/>
    <dbReference type="HOGENOM" id="CLU_586619_0_0_1"/>
    <dbReference type="OrthoDB" id="10384129at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="140"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="466" mass="51247" checksum="F53649C204FDAA3A" modified="2013-05-29" version="1">MGQAISTPYTCPQCRGPFPQSSKHCPSCGYANHIFISAARYGVPSPSRSSTERAAALQAAPADSTPCAYCAWPIRKGQMYCNECGHPQPATEDPAWTPRTRQLMLRSPSARSPARRERDLEQLDDRRAAEVPHPMGVEALVTPTGRPTRKLEALSNALFTLLTSSNSNALTGSHSKKQLVDIPRLNYLEHKLGRRPEYMLSSFDPSAVLAVYKSMNLEHTLVPFPPPAQQLDAPCLTRLGLMQYLQHGILFDPHEAVRELQQLVADTPELPAPPAWLANAQVRAGTLQPGGKGAWIIEENMALSKPHPLAEQRQEKVLIDLEQMGFPIPGDPPTPRRRRRRPEALAAPLNSAAAGGMGEEFLSPHTNPYHAFPWGSYPSPYTPYTPYAHLYAHPYQSPMPWAAYPPHPYSPQRSPYRLSPALPQDVYRPLAGGAGAGVGGSPRARALAAAAAAEEDWDYRDFEDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBX5</accession>
    <name>M5GBX5_DACPD</name>
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        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_49791</name>
    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630471.1">
        <property type="nucleotide sequence ID" value="XM_040774941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBX5"/>
    <dbReference type="GeneID" id="63690003"/>
    <dbReference type="HOGENOM" id="CLU_1111365_0_0_1"/>
    <dbReference type="OMA" id="THNTRKL"/>
    <dbReference type="OrthoDB" id="70376at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="27157" checksum="B5A84AFB432E8B2C" modified="2013-05-29" version="1">MLIECTRIFNAELALPAQGYQALLTYPPTNSNFQLAMYQLSLVRAAALAQIDKDEEYALECADIAREDERRVIEEEWKKGREDARQRMIAGLGEGRRKAKEELEAQDIAAGQPRQTRKLRGQAGSGPPSPPSEPTTGKETVPVTLPKEMNHAQAILGLSGPPETNALSLTSGIPSKYTMPLSNGRENKKAKGSQAGANGRWSLGKAVPSLDKKNEGEIEADMAMIRNGGKKRRVVAEKDRMGSTTGGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC39</accession>
    <name>M5GC39_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450 monooxygenase pc-bph</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_52716</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC39"/>
    <dbReference type="STRING" id="1858805.M5GC39"/>
    <dbReference type="GeneID" id="63690187"/>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OMA" id="TYDMVRD"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10 12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="539" mass="60028" checksum="5F2449CEB45BD7D1" modified="2013-05-29" version="1">MSSLLDYFPTPFSSNALLLYGGLAVLLLVASHLVPWVADPFGYRKKHIPGPFLAQLSDVWLARVAAQGHRSEIIHGLHQKYGKVVRIAPNHISLSEPGALQIVYAHGNGALKSDFYEAFVSIRKNIFSTRDRAEHTRKRKIVSHIFSQKSVLEFEPYIRQALGKLVKQWDSLLSDDRKLASHRLRPNENGTAWFDCLNWYNYLAFDIIGDLAFGEPFGMINSGADSASVAIHGDDPTHLASGEKKLEIVRVPAVKILNDRGEYSASMGCLPIWIRPYAKKIPWYAKGNQAVKNLAGIAIAAVDKRLATPTDRVDLLARLQQGKDEQGNLMARSELTAEALAQLIAGSDTTSNSSCAITYWLAKYPDAQRKLQKELDEALGDDEDVPTYEQLKRLRYLDAVVNEGLRIHSTSSLGLPRIVPEGGLEVSGIHFPAGSVLSVPSYTIHRDTAIWGPDPDIYRPERWFEQDAEGIQATFNAFSFGPRACVGKNLASMELLLIVATIFHRYEFALLSQDQPLETREGFLRKPVSCYVGMKRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCG2</accession>
    <name>M5GCG2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dak kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_31991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628650.1">
        <property type="nucleotide sequence ID" value="XM_040774355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCG2"/>
    <dbReference type="STRING" id="1858805.M5GCG2"/>
    <dbReference type="GeneID" id="63689417"/>
    <dbReference type="HOGENOM" id="CLU_017054_0_1_1"/>
    <dbReference type="OMA" id="MLSAACP"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="6">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="36260" checksum="89257CD05618637C" modified="2013-05-29" version="1" fragment="single">SLRALCLTNPHLTLHTPSKTLLLQQAPKGVPVLCGGGSGHEPFAAGYVAPNLLAGAVSGEVFASPSARQVLDAIRLLSVQCPGKGVLVLHNNYTGDCLHFGIAAEQARAAGLQVETVVESDDVSVPRSRSQKVGRRGLAGIILTSKILGAASSAGLSLSELKLLGDLVNASTGTIGTGLDHCHLPHTPASAWEPLEGDDLEVGMGMHNEPGVRLIRGGIGAQELAKEMLALLLGEDEERGFLRWEEGDKRLQGGEGPVLLVNNLGGISNLELSAFAHEVLIQLEKDYSLRPGRVYVGAFLTSLNSPGLSLTLLNSAEVQRALPQELKGKVNVLELLDAEVDCPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCK0</accession>
    <name>M5GCK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosine-purine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_52402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628715.1">
        <property type="nucleotide sequence ID" value="XM_040775105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCK0"/>
    <dbReference type="GeneID" id="63690167"/>
    <dbReference type="HOGENOM" id="CLU_021555_4_1_1"/>
    <dbReference type="OMA" id="RWHILYV"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000001">
        <property type="entry name" value="Uracil permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012681">
        <property type="entry name" value="NCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00800">
        <property type="entry name" value="ncs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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        </location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN9</accession>
    <name>M5GCN9_DACPD</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Agaricomycotina</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
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        <text evidence="2">Belongs to the SVP26 family.</text>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:COPII receptor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Svp26/Tex261"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144:SF0">
        <property type="entry name" value="PROTEIN TEX261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144">
        <property type="entry name" value="TEX261 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Erv26"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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            <end position="30"/>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD38</accession>
    <name>M5GD38_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
        </recommendedName>
    </protein>
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    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775807.1"/>
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    <dbReference type="STRING" id="1858805.M5GD38"/>
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    <dbReference type="HOGENOM" id="CLU_1346018_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23675" checksum="18026A536F1653B3" modified="2013-05-29" version="1" fragment="single">MGTLNEKSSNLMCRLERRVIYPNGMRPVEIHCHRSNVNWTNQNCISDLPGMPVTYAAIDTKERRETRKGRQAIDRMFDKERAPVTLTLKVNAPVILLRNMPEHVELVKGRFGTVLGFVTHTDWESRGEDISLFTDMELYPTKATVFKDLIDSSTRYPIVRFKEIAHLRAITVLVCPQDWEVMRTWGEGQTRSFGGYRRQVSQCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA0</accession>
    <name>M5GDA0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosylmethionine decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20929</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="4"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631276.1">
        <property type="nucleotide sequence ID" value="XM_040772149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA0"/>
    <dbReference type="STRING" id="1858805.M5GDA0"/>
    <dbReference type="GeneID" id="63687211"/>
    <dbReference type="HOGENOM" id="CLU_023050_0_1_1"/>
    <dbReference type="OMA" id="WFEESSN"/>
    <dbReference type="OrthoDB" id="1068353at2759"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001985">
        <property type="entry name" value="S-AdoMet_decarboxylase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018166">
        <property type="entry name" value="S-AdoMet_deCO2ase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00535">
        <property type="entry name" value="SAM_DCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01336">
        <property type="entry name" value="ADOMETDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0704">Schiff base</keyword>
    <keyword evidence="8" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="50911" checksum="2F569C588C3B28B8" modified="2013-05-29" version="1">MTAISVATTNGHHVHQHHHQHVDVIDDSIVAEMQSSTPFEGPEKLLEIWFAPSADHLPVVDEAKYGSGYVDGDGNPKRQGLRRIHRAVWEEMLDIVKCKVLSVIVGEELDAYLLSESSLFVSPHKIILKTCGTTLNLLGLPRILDIASRYCGFSKVWRCFYSRKSFMFPERQLGPHREWGEEVRYLDAFFRDGSAYTVGKVNGDHWLLYLTSPVEDDDDALEPVTYGSRLRMYTPSPTPSLEDTPTLSDLQQDYTIEILMSHLSTSARLPFFYHQKEAADGRGHAYAAKLSTELGIDTIFPVDRTTLDAFAFDPCGYSANALIDWGGGEGYYTIHVTPEAGWSYASFECNVPLPTRDSSALGVRGLDPDLPDLQTLVRNVVNIFDPGRLSVTLFVSTSAKSDVAIETAQKVFKQALSPRGYYRNEKINYEFGGYDLAFASFRRLGTKGRNMADKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDL1</accession>
    <name>M5GDL1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629397.1">
        <property type="nucleotide sequence ID" value="XM_040770148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDL1"/>
    <dbReference type="STRING" id="1858805.M5GDL1"/>
    <dbReference type="GeneID" id="63685210"/>
    <dbReference type="HOGENOM" id="CLU_690819_0_0_1"/>
    <dbReference type="OrthoDB" id="3359616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="42436" checksum="0CDFF6E04D432A12" modified="2013-05-29" version="1">MSDQTLNTTIPSFDPTVSYQPSGTWSPVGILNGSTGGRAMFDQGSLPGYITYTFPQPATGFEYWGFQRSDHWLMSICFDCPPGDTGGDQVGTGLNITTNGSEPPRLLYSVYNLTYAIHNVSCTNLFDPRTSIKFPTPSYGQMNLDHFVLVSPTTPPTSTSTSSTQPDGTATAGAGGSSSSGSHVGPIVGGVLGGIAGLVILFLLFFFFWWRKGNNRGSGLSQDMNGGFELKYEPPPGDGIRPSIVVSPQQQPILETSPIMSLTPSTVLPTISPMIMPFVSPMMVGMQDAGSFLGPSVSSGPSEIGGDRPLPARAGTATTASTTIRPRKITSELTGSAVTRSGETVTPSVYPASPDANGPPISHRIPRRRDQDAGFLQGDELAEDILPPDYSAATGTSRPRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDN3</accession>
    <name>M5GDN3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HCP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_51143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629457.1">
        <property type="nucleotide sequence ID" value="XM_040775028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDN3"/>
    <dbReference type="STRING" id="1858805.M5GDN3"/>
    <dbReference type="GeneID" id="63690090"/>
    <dbReference type="HOGENOM" id="CLU_000288_126_3_1"/>
    <dbReference type="OMA" id="MIYDKGC"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="416" mass="45515" checksum="42B41FBCB9956CDD" modified="2013-05-29" version="1">MYAPSQKGGDTASLAAPPLLDHSHLRPGKSALLLSHDRTLELYRANAKKTNDPELQFEFAVFMIDAAKSLPTTAISAGDASNPVAQEKAEARQTELLREALGLLKRLADRGHSPSQYFLADCYANGLGTARGKQDFDRAYPLFVLAAKHGHPDASYRAGTCCENGWGCRRESAKAVQFYRKAAAALHPGAMYRLGLAELNGELGLSRSPKEGVKWLKRSAEHATHEFPHALHELALLHERGVENVIFVDYAYAAELLAQAAELGYAPSAYRLGECYEYGKMGCPQDPALSIHYYNIAAQQNHRDACFALTAWYLVGSPGVLPQSDTEAYLWARKAAEQGLAKAQYAVGYFLEVGIGVQQDLHEAIQWYKKAAEQNDKRAIQRLRNNVAAAGPISPQDAILSRNEQDTGKDGGCIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDS2</accession>
    <name>M5GDS2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histidine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_21679</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629542.1">
        <property type="nucleotide sequence ID" value="XM_040772496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDS2"/>
    <dbReference type="STRING" id="1858805.M5GDS2"/>
    <dbReference type="GeneID" id="63687558"/>
    <dbReference type="HOGENOM" id="CLU_025113_4_0_1"/>
    <dbReference type="OMA" id="CGGGNFK"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01200">
        <property type="entry name" value="WHEPGMRS_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000015">
        <property type="entry name" value="Histidyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="14">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="70"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="571" mass="62954" checksum="0CEF53141A954A0D" modified="2013-05-29" version="1">MADADALRAKMKASGDHVRTLKSQGAPKEQVEAEVAKLQEAKKELAEATGEPLGEEKGKKGRMALKTAKGTRDWAPSDMALREHIFSTLTRVFKKHGGSTIDTPVFELKEILAGKYGEDSKLIYDLQDQGGELCSLRYDLTVPFARFLAMNPIHYANIKRYHIAKVYRRDQPVMTKGRMREFYQCDFDIAGHYDPMVPDAEILCIVCEALGELEIGEFTVKINHRKILDGIFAVCGVPTEKTRTISSAVDKLDKLPWAEVRKEMTEEKGLDHEVADRIGKYVMLKGGPELLDRLKKTELANNAMAKQGMDDMELLFTYLDIYGISDKMSFDLSLARGLDYYTGIIYEAVTHASAPPGFTTVPSVPSTEAQPSDHHSGPSAPSSKSKKPKKDAEGEEEVDEATVGVGSIAAGGRYDELVGMFMSAAAGAGGSSKKAAGIPCVGISVGVERVFSLLNQKAKADEESRWGRSKETDVFIVAVAEGLLAERMKLAKELWDAGIKAEFMHKAKPKFRAQFETIEKERVPFAVLLGPDEVKQGVVKIKAQKGKEEGKEDEGEIVERVCLVSWLKERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDX7</accession>
    <name>M5GDX7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prefoldin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_21744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629677.1">
        <property type="nucleotide sequence ID" value="XM_040772532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDX7"/>
    <dbReference type="STRING" id="1858805.M5GDX7"/>
    <dbReference type="GeneID" id="63687594"/>
    <dbReference type="HOGENOM" id="CLU_122140_0_1_1"/>
    <dbReference type="OMA" id="REMIQQK"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="75"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14176" checksum="E339D059987C2CDD" modified="2013-05-29" version="1">MSGLSDDTLHKVLQQIQARTVAAQRELSLVRAQIAASERARKISQLTSGEISALPEGEVVRVYRGVGKMFVQEPRKVMERSLEVQEKDIEEELQALNKKAKRLEDEYQRTQGQLRDIFHSQQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDZ5</accession>
    <name>M5GDZ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7587 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631846.1">
        <property type="nucleotide sequence ID" value="XM_040771964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDZ5"/>
    <dbReference type="GeneID" id="63687026"/>
    <dbReference type="HOGENOM" id="CLU_625587_0_0_1"/>
    <dbReference type="OrthoDB" id="3359845at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056009">
        <property type="entry name" value="DUF7587"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24494">
        <property type="entry name" value="DUF7587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7587" evidence="2">
        <location>
            <begin position="15"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="438" mass="47903" checksum="A30CA87D5E24DBF4" modified="2013-05-29" version="1">MARYDLPSRLAGHKHLFLVDHALSQVPYDPARGFVAPRFANLWPDEIDAQETEPGLEDEVVRAHVRGRALKDAGGRRGKSPWVDASASWLLALWHASALAERGYSDVHLSVISVNSAPPGAQRERKWYALDLLRTGKSPALSVDELSAEERWASVFQQVLVFGHIPPSAIVSRVPVERLIPALPANFFHPGESRTLDNLIWFNSPQKGVRIVAPVGISAGDPAHPGVHTEEEIGHAGARLAIATLHVPPCAILAYRLPIDALAKEIAQAFSSSAYPSPAWERIERAVQKEIDCRHREFVQGVKEFVTLELEYAQQSLDDITVLVKGTLEDNFMRPPRPHRPHYADFVNPGEASTSSSAQGSAGGPRSVHSADTAAQSNTLSRLAGIIEATREFENCIRAARRVLDWLVPLREEDELVKEVLLAAVGALAARGVEDAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE79</accession>
    <name>M5GE79_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_50562</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629947.1">
        <property type="nucleotide sequence ID" value="XM_040774994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE79"/>
    <dbReference type="STRING" id="1858805.M5GE79"/>
    <dbReference type="GeneID" id="63690056"/>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OMA" id="VHWINIE"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF18">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="48"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="546" mass="60134" checksum="CE272568F1C48679" modified="2013-05-29" version="1">MDLEKASYEDKADDQAGTARAVPILDPEIDIIDFEEKKELKRGLEQRHIQMIALAGTIGTGLFLGSGKAISRGGPVGALLGYGLTGVLVSCVVLSVAELSALVPLSGSIIRHAHFFFDPALSFAQGWNGVYSNCVGLPAEIVAAAVLIDFWSHGISNGVWITILGLLLLASNLFFVRIYGELEFSFATLKILLILGLILMGLVIDLGGGPDHHRYGFQYWKNPGPFVQYLGVPGPLGQFLGFWTTFSNAAYAYSSIESVPNAAAETRNPRRNIPKAAKRIFWRVLIFYVLAIFIVTLIVPSNDPNLLQSTGNAAQSPFVIAANRAGIKVVPHIINAVVLTSAWSAGNSGMLNGSRNLYGLALEGHAPSIFKRVNRFGVPWVAVCFYGLFLCLGFMTLNTSASTVFQWFQDLVSSAALVHWIIICAVYLRFYYGCKAQGIDRNELPWKGPFQPYAAWIGCISFGIILLTAGYSVFMTGKWSTETFISSYFNIPLIFVLYFGYKFTRGTKMVSLEEMPIKHFLQIAKDNPEPSEKPLRGWRRLNILWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GER5</accession>
    <name>M5GER5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_45703</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632521.1">
        <property type="nucleotide sequence ID" value="XM_040774660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GER5"/>
    <dbReference type="STRING" id="1858805.M5GER5"/>
    <dbReference type="GeneID" id="63689722"/>
    <dbReference type="HOGENOM" id="CLU_006301_5_2_1"/>
    <dbReference type="OMA" id="RKNPWMN"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000007">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 14" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="90"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="625" mass="67604" checksum="7FE3CB290C4B5FDA" modified="2013-05-29" version="1">MVKQVQKDVYIPTVVSVSNLARILDMRQKRMMQLMKNWGMEEVKPDLLVLSSEDASLVAVELGFNPVIDDEAAFDIYPDAPPAEPSTLPHRPPVVTIMGHVDHGKTTLLDTLRSTSVAKGEAGGITQHIGAFSVPVGTASENSAIRTITFLDTPGHAAFTAMRARGARVTDIIVCVVAADDGVMPQTREVLNLAKTEENVELVIAINKVDKPQANVEKVKNALLAEGVQLESLGGDVPSVEVSGLTGKGLDDLIETISTIAEVADLRADQTSKAEGYVLESKVDKGRGPIATVLVTSGTLQPGAAIVAGTVWCRVRQMMDDKGQFVKKASPGMPVTVSGWKELPEAGDEVLQAIKGEDDAKRAVANRKREIEKRKILKDVEKINEVRKAERIEREEAALAEQMGVTREAHEGKQEQGQKELRLVIKGDVSGTVEAVVGSVSGIGNDEVTTKVVSSGVGEVLESDVSMAEASNAMVIGFNVKCQRSVQQQAGKLGVPLYFDDVIYRVMEEVRKRASALLPPRIEKHVKGELQVAEIFHISLKGRKTHDVAGCKVTNGVLEKSSRVRVMRNGEEVWEGMVADLKHMKKNITEAKKGMECGISLEGFEEVLVGDVIQAIDVKEIARQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF16</accession>
    <name>M5GF16_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630642.1">
        <property type="nucleotide sequence ID" value="XM_040768162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF16"/>
    <dbReference type="GeneID" id="63683224"/>
    <dbReference type="HOGENOM" id="CLU_2399630_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="93" mass="10291" checksum="C9DF60483838ECE6" modified="2013-05-29" version="1">MPAGKPKFLLLSMHTCSGDMSMVVVWILHLVLSKSMGKEVKKEVHISNCSHGKGFKAIPFIANMMATVSLHMFLNADTLPQAQINLNWPSPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFA0</accession>
    <name>M5GFA0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_63550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630872.1">
        <property type="nucleotide sequence ID" value="XM_040775734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFA0"/>
    <dbReference type="STRING" id="1858805.M5GFA0"/>
    <dbReference type="GeneID" id="63690796"/>
    <dbReference type="HOGENOM" id="CLU_001724_12_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080043">
        <property type="term" value="F:quercetin 3-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080044">
        <property type="term" value="F:quercetin 7-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="34504" checksum="5BBE4958A9B9AC7C" modified="2013-05-29" version="1" fragment="single">MWIRDHRVAGDVVRVVGLPPYFQWEDFPQPVYPPPLHTFMITGEKMVDAADGFMLHTVEELEMEAHKDMIQWVRPRRVLCFGPQLPPALLSENAHSSAETLAKLDVNFNASPASDLADCRNDASNAAAGEKLAVDPTIAFLDKALEKYGVHSALYVSFGSMLFPPEAHMKALIETLLNLENPLPFIIPISTGSIPEDMKTAMEQSGRGLVVQWAPQQAILSHPALGWMITHCGGGGMFESLSSGVPVIAWPFMVDQHQHALWISQVLDTGFELLQVRTGTPGRPALRGDNPGGILILGTDEAIRNEIRDTLERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFM0</accession>
    <name>M5GFM0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633331.1">
        <property type="nucleotide sequence ID" value="XM_040769575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFM0"/>
    <dbReference type="GeneID" id="63684637"/>
    <dbReference type="HOGENOM" id="CLU_1320856_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="208" mass="22428" checksum="71959B2828F9F5D5" modified="2013-05-29" version="1">MVAPPPAAPVPDWTPTTPFPLLPALSHPSSPSPFLTSPSPPALAASPNPSTSLPAPSTSPTPVTPGPPSLMPLLDFYGRAREWTAAARLSLEPSPPPSPPRAVMRPKKVRRRGRPYPPQPSIIIKAEPEEVSLHAAVVTPPAGLGLPMAPPSMRALEGELVAGTVVQEEDARLQRLLGDYERMLWERVESCERIERLIEDSARMFADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG13</accession>
    <name>M5GG13_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20338</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="9"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631582.1">
        <property type="nucleotide sequence ID" value="XM_040771897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG13"/>
    <dbReference type="STRING" id="1858805.M5GG13"/>
    <dbReference type="GeneID" id="63686959"/>
    <dbReference type="HOGENOM" id="CLU_014563_1_0_1"/>
    <dbReference type="OMA" id="HPYPGNF"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF1">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE I_II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="13">
        <location>
            <begin position="182"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="59043" checksum="BED282CA73555FB3" modified="2013-05-29" version="1">MSQESTEYKSADSLPAYAYDSTAHLRPYTYPRSSVHAFFDDTRIKKKKWYQRPYVIALLALCLLAVVALGVGLGVGHTLGRASTAATSSGGTGSGQAGTPAPSNSSSPSPTYNITAFAPLPKWNWTDPSQKLIGISLGNYLVLERWMSEDWFVNSSSPDAWDEWTFSNFTGSDAAGLLQAHWDSWVTEADVDTVWKAGINTLRIPTGYWAWIQTEEGEPYVQAGQLDRLERVMSWAYKRGMYVLIDLHGLPGSQNGEQQSGHNTTDVRFYQPAYQSRADATLSTALGWISASPYRSTVAGIEVCNEPVPNSADNFSVLRAFYERSYAACTQRDDPVPMIFHHGYPDTDHLAYWLDFVTGKDPNYLILEDHPYPGNFPLQTDSQDILAQVCQDASSYQGYPVPVAVTEWSLTTGLNGSSFETRFYEQQVTAWAWSAGGVFWSLRANQSLLGVAAAPPEQQRQYSFLDLLGEGVVPLPQGNQTSQEYLQSLQGLEGGQGQGCGPVPGEKWGNASYTSVAAEPTYTSGELTVSLPAATGIAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG31</accession>
    <name>M5GG31_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631672.1">
        <property type="nucleotide sequence ID" value="XM_040767964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG31"/>
    <dbReference type="GeneID" id="63683026"/>
    <dbReference type="HOGENOM" id="CLU_2209924_0_0_1"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="12073" checksum="ED55E4578EB0BCD0" modified="2013-05-29" version="1">MAKHNSCQRQQQQGIWNGTHDLNKKRGFLFWFVQNLFPLLGSFTARPLLPSTIPYPLTPILPSLCLSLLFVASTAYTESITLSRYPVAYKAYQARVGKFSPGHAVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGY1</accession>
    <name>M5GGY1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_60933</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633172.1">
        <property type="nucleotide sequence ID" value="XM_040775655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGY1"/>
    <dbReference type="STRING" id="1858805.M5GGY1"/>
    <dbReference type="GeneID" id="63690717"/>
    <dbReference type="HOGENOM" id="CLU_010365_6_1_1"/>
    <dbReference type="OMA" id="NIYHRWV"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="305"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU06278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="582" mass="65468" checksum="524913BBA797EC13" modified="2013-05-29" version="1">MPSTGASRGMLVDNKAILARLHRLWQKNFYPIVLWIIVLGILLVISACHQYRRSMERSLAVRKDKENEEEEETLNGDAHPDRRTSSVQCFLRMLLSEWNILMYRRTIPMWWNYRMTIAEMLFCSGYLVVLLVLGLVDSNGLQYKAYANRCGHLATSQIPLIIGLAGKNNVISYLPGIGSEKLNVLHRAAGRSALVLALLHAYGRWQNGLKGHNAINTPRIIWGLVALSSFTLLTLMSVRPLRNKAYELFLATHIVLVFTFVLAVSYHRSKSYPYVLVGWVLWAVDRLGRCLRVGILNRLWLNFNPFWRNPASTATVELLSADTMRISMRRHMRWKPGQYAYLIMPTISFLVWESHPFTIASVSDTNGRQENELTFIVRARDGFTKRLLAHAQRGRKRQLAVECAMEGPYGCPPSLAHFSTAVLISGGSGVSYTLPQFKSIIHDVRNGRSATRSVCFIWVVRHADHISWISTALASILATAPEFINISIRIFVTQDSDSADQRPSKPLPSFPIMSIAPGRPDLRMLLVDEIERAAGEVSVNVCGPPSMTQTVRTILAEGPVAGPVAIRRGCPPVELHVETFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNR7</accession>
    <name>M5FNR7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770717.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
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    </feature>
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            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="15"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="388" mass="42718" checksum="A193E0C92CA6BDCB" modified="2013-05-29" version="1">MSAVHEFDHERRSTSSDDSFPEPVTPPYLTPMSSYMYSPSNVDAGVLDIGDRSPSVTSLPLGPLITVDGRTQPAQDDPNATMRQKNIPGYGYQQTSPTRFFEPFPEGPIPAEQFRPRRGFIPSIHVPHEFALITLSEGNLVRMLGFDEGAVGAVREVLSSQEGEKQGVRSERRGKEAQHPQRRKSTDSAREGRVLSPVNVAASPVEGEMIEWCLEGKPWKERKNSSEIFFTSVISTLLKHSYHYVSPLNISAPGSPLHFSGIFSRSIEPTEERRCAFSVSFPAANIIRVIGAPRESTPGILAVVRQGWGQRLKEEKSEIGAWEGRLKGPGLFGAVPEPPGPEVVLETLAAFNRQGIELMTLVRLAGTEMWLFDCPASKEESMTISTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNU1</accession>
    <name>M5FNU1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LAG1-DNAbind-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_102198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624823.1">
        <property type="nucleotide sequence ID" value="XM_040767617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNU1"/>
    <dbReference type="STRING" id="1858805.M5FNU1"/>
    <dbReference type="GeneID" id="63682679"/>
    <dbReference type="HOGENOM" id="CLU_301482_0_0_1"/>
    <dbReference type="OMA" id="IGPMERR"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="8">
        <location>
            <begin position="352"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="9">
        <location>
            <begin position="509"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="232"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="720"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="867"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="991" mass="106981" checksum="BF6871DC61593AED" modified="2013-05-29" version="1">MSSPPTFSSIDPVRGPPLTQLDPVGSRSSKHKPWGVPSPAPTWSDHTAGPNTSPAHSPMHQLLTPPADQRTPQLASSSSLDRYLSSGRSPVAASSSSASITGRPAGRFQTLSPPVSRSASGSAAHASRSQDNTTGDSEPLSARPGVSAHRHGSGSTSTRPAGFPSVPELSGPSAPLVLQSPAREPLVSVSESPSRRNAYSSSAPVNLSPPQAACLRYPLYLERSASPVPVPAQVQLQDPGSDIDDPSEAASAHSYQSMFQVQLTGRSGSTGESSRSQRHPYTKYITDDEAIEQARGQKRKPSYTHTISDDRHNKMRRSAEARLSGGSFPNYTTSQSQMPVQKRPDPMANMITITCFHPIVAQKSYGAEKRYFSPPPFVAIRGPLQNAPSQALEMNVITGRESGGSGDVESTQTQFLDGNFIATFRTLHVGGMSNRKRCQLRLTISDASTSDVPETVDALASRPFMAPQNPFYLLPMSVPTGARKWATFLSAPIAILSKPAKHMKSHDPSSITFGSTVSLYHRLNSQTARTKYVHINSARRMLETSGASWTPLVVERVDTPAGPGRPGGLSLPYTAPSFAEGFGSLPDPDPSLHTPRIAPLPQILDVRRLEVLAPVTFNSTITLFDPQTGVRSPPLIIKKVVNGHIKPDEPSFGDPLDPLNHLGASSTLRPLEPVGQLQKVAFMRPPQTYPRGRVATGTEPNMYWGTPPDSDEMMFGTPIQSGRPARAYRPRSRRLAAAMESQSQPEEPDEGLEELDDAVVWTIVSVTNFKYSYFASDPGRVIPPEVAAASVTPFPALRQEPFYRPQMHALQLLVDDFDQSLEIWVGSFGPLRVSLLRQGTDQQTRKMYDPRTWFEVKRPPVDQPAAEFAIGGGSLPERTASSVSPTASPDAQAGSSKTGPKPLRAKIPPALDVAKPQTVLQVDLPPILHLVRSCFRNEPAGNAVTDLPIIFMRTLDGTGFHSGKSIVVENILGEHCSRNDVAGWTVRVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNV0</accession>
    <name>M5FNV0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rdx family-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_84316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624853.1">
        <property type="nucleotide sequence ID" value="XM_040776675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNV0"/>
    <dbReference type="GeneID" id="63691737"/>
    <dbReference type="HOGENOM" id="CLU_068510_2_0_1"/>
    <dbReference type="OMA" id="EYCTQCR"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="17200" checksum="A772B769F52BEEAA" modified="2013-05-29" version="1">MSAHQDNDTGCLTGQCGPPIVKDTPTQERAPFDPLDSTTFTHPEIDKLSPQVIIEFCDRCRWLHRATWIQTELLLTFPPPAIQSITLIPLNTQETGARFRVWLLAENSMQLVWDRKMAGGFPELKELKQRIRDVILPGKSLGHSDTHKAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPE2</accession>
    <name>M5FPE2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_119798</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623906.1">
        <property type="nucleotide sequence ID" value="XM_040770869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPE2"/>
    <dbReference type="STRING" id="1858805.M5FPE2"/>
    <dbReference type="GeneID" id="63685931"/>
    <dbReference type="HOGENOM" id="CLU_004415_0_0_1"/>
    <dbReference type="OMA" id="IMMARSI"/>
    <dbReference type="OrthoDB" id="19092at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07651">
        <property type="entry name" value="F-BAR_PombeCdc15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000045">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000312">
        <property type="entry name" value="Related to Cell division control protein 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="11">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="10">
        <location>
            <begin position="877"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="187"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="448"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="570"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="677"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="735"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="764"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="782"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="940" mass="104330" checksum="ED8AC297CA41C4E3" modified="2013-05-29" version="1">MAQRRPSSAASLAQYIHQQDPPADPSGLDFCNAFWGPNDAGYEVLLARMRGAMRTMEELRAFWKERTVIENEYATKLTKLAKFTLGRDEIGELRNSLDTLKMETEKQAAVHQELAGKMRQELELPVASFITRQISHKKTIQSTVEKSFKNKQAQEGHVSKARERYESDCLRINSAIAQQTLVQGKELEKVRMKLERAQSTIANNEKEYQNFTRALQETTKKWEQQWKDFCDTSQDLEDDRIEFMKDNMWSYANAVSSVCVSDDESCEHTRVSLEQLEVDRDLETFISSYSTGSIIPDPPRFVDFRAGAPGDTQQRRGRQARFVRESKKIGAPLYGTTPGEDYELDERAVSGGSRAATPFESHPALPPSQPPPSAQQPPSMQQGPYPGQPGGRSAPLEPVMLNVGSAAYHVDPNADPQRALSNRRPSVSNSINASSAAPGGSDDPLAQAMNQLRQDSVRRGTTPTQKGTGNSVTSPSSAYSNHASSGIPPGRGPAQPVNYDSISDSVVGGPPPSVTSPGANGPPMAKFMQEPARQGGELPVDNVLRNYQQSFPHEHKGSSRPSSALSRRSTQVVSSPGMNPPQQQQQQQRPVSPAREGFSGIGAQGRSPSPLFQQNPQVQRAISPYAPSVSSGQRMPQTESPAAMSGRALSPQPPMNGHRPVSPAGVYGIELDASGKVARDSVAEEYQRKIREEDERRRREEEERVRRQREEEDRARRAREEEERRRLEDLRQRQLAEQARLAQQQQPQQTGYNQSAARGQYSNYPPPGQPQYQQPPPPPQPTQQQFPAYQQPAQPQGYGPPGSQPQQYGQAPPSQFPPPPRQPSYDNYYQQGQQPPPPPIQQTSQQAPAPPPAREMQPPQGNGNPPPTGQWTSTGEGILFYVKALYDYQATIEEEFDFQLGDIIAVTATPEDGWWSGELLDEARRQKGKHIFPSNFVCLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPE3</accession>
    <name>M5FPE3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625383.1">
        <property type="nucleotide sequence ID" value="XM_040769146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPE3"/>
    <dbReference type="STRING" id="1858805.M5FPE3"/>
    <dbReference type="GeneID" id="63684208"/>
    <dbReference type="HOGENOM" id="CLU_014627_0_0_1"/>
    <dbReference type="OMA" id="HAREQHF"/>
    <dbReference type="OrthoDB" id="449091at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF4">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="914" mass="99821" checksum="D83A9AC8A7872834" modified="2013-05-29" version="1">MTSPQVTLNPSFSALGPFPQHAREQHFLSPAFPFPASRPPLYSEIGRGRWTSALADGGEVGWSSVWLEEGELALSYPQVRWKELRSTAGWAALQHHSLLHTTLSLPALSSSYTLELRVTQASFFCLLPRERNHTDTDSVEWHHANIYALAHYPPSPFPLLPSPAREYDLYISADYEIRLFGDPHASTAGDVPVTRIGVSAVLKELTQGPQAWGEEDVVPDVVGGWALGHAFGLGLRGGAERVRLLRVSLTDCPGLQLQLSPKEERWTLSPLQVRVLPVPFLQISSLPPSVHELEFDLHFSSSGEGEGGEYTYTIRRSLPLRHRRAWWEHTSHEPLLATYFLSGHPQAFLALPPLHPHPHPQPHPQPPLLLALHGAGVSLSSPFWPAALDRQAHSWALFPSGGTEWGLDWHGPSAQDVWGCAGSFRSLLSPSTSTSTSAPRQWATYAPGEKTVLIGHSNGGQGVWYLSSRYPDLVRSSLPASAWLTPAHYVPLTFSRSAHFLDPFLRGILDSALMGEGNDLFLSNLLGSNVLALHGGGDENVPVWMTRKAVGLAKSWGAKRVEYDEIERKGHWWDEVFRSPRARAFLDQALNPHREAREVPEKWTLTVQDPFEAGGMFNWSIDELLLPGRLGRLSVHRAQGEGEVQVRTTNVHAFSVGELGGPPGKKLQVRVDGQLLPSSQGKWVLTSSGWAAAASAVNAVNPLPLPPVPAGPISSILTSQGPITLVLPRSPSRSRSGHASVAARLARAVFLYLRIDVQIVFDDEVLGLAGDEGRTDGERGEVQGLEKLGKGNLILLGGWENLLTRRLLQANKSFTFEGGHLHLSGHTFSSPGLGVLFLLPHPRPHPTSSSLALVLTGTDPSGLERALRAFPLRTGVPVTQWMVLGDEGDWQGLGGVRAAGWWDRSWGVGGGWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPU9</accession>
    <name>M5FPU9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_112640</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623497.1">
        <property type="nucleotide sequence ID" value="XM_040769456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPU9"/>
    <dbReference type="STRING" id="1858805.M5FPU9"/>
    <dbReference type="GeneID" id="63684518"/>
    <dbReference type="HOGENOM" id="CLU_015166_6_0_1"/>
    <dbReference type="OMA" id="WVMYEQM"/>
    <dbReference type="OrthoDB" id="269120at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="16"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="168"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="262"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT96599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="38286" checksum="56BA78B1C447B55C" modified="2013-05-29" version="1">MASTPPPSFSTNWIPAKSWTHFVAGGLGGMCGAIVTSPFDVVKTRLQSNMFRHSLAHDRAPHHLATPRPHLATASSSSNTPSFRPRMPAGAHPAHTAAQVAHTSRNILWAFYDTALLIRSIHKYEGSAALFKGLGPTLVGVVPARSINFFTYGNGKQIIANKFNNGIEDTWVFLTAGALAGIVTSTATNPIWVVKTRLQLSASQSQPFTSSLACIRHILAHEGIPGLYKGLSASYLGCAESTIQWTLYENFKSSVRGRGGATEWLGMLGAAGAAKMIASLITYPHEVVRTRLRQPIENGRVKYRGLIQTFTVVIREEGVRSLYGGLSAHLLRVVPNAAVMYSIYEGLLAWYGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQI7</accession>
    <name>M5FQI7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626058.1">
        <property type="nucleotide sequence ID" value="XM_040770497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQI7"/>
    <dbReference type="GeneID" id="63685559"/>
    <dbReference type="HOGENOM" id="CLU_871602_0_0_1"/>
    <dbReference type="OrthoDB" id="3363415at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067057" description="Ricin B lectin domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="32256" checksum="9892D683F6781DD0" modified="2013-05-29" version="1">MQLSLTQSVVFVLLVLDGTSAAVIPHERRAALVTEPQGLVDPVSVTGLEILPDVTVTLDGLHMHQRGLLDPLLGPNGILGALPGLLTGLLGTVTNVLGGVLGGLGLGSILIADPSTGAQGMHVYLVQASNTSIAMATATNATDPALLAATNMSNSDLVLATLHVPVVNQTTMNIADMCITSTGPSANNMTASPCRDVSLAQLFVYNTKNNAVYSVTDLLTCSYAAGNATTASPGAALTGTANIIMVERDAPTLPACNGTMKAITFTPANSNPNTQAPVTVAPGQAVGTTGSTTAPSLDYAAGDHDPNAMTDGTANNNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQR5</accession>
    <name>M5FQR5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication factor A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_17466</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626183.1">
        <property type="nucleotide sequence ID" value="XM_040771288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQR5"/>
    <dbReference type="STRING" id="1858805.M5FQR5"/>
    <dbReference type="GeneID" id="63686350"/>
    <dbReference type="HOGENOM" id="CLU_421512_0_0_1"/>
    <dbReference type="OrthoDB" id="10045553at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067152" description="Replication factor A C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="3">
        <location>
            <begin position="410"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="650" mass="74341" checksum="1CE6A053035D4269" modified="2013-05-29" version="1">MRSFILLFLASILAVASAARMSCANQGLLKKPKPPRLGPGLELSDGDWMFRMTAGLKIHLSWNVGTLKLYNVIKVTTYRQWVPWGLNKSDIVVQDYGKMGSAGTLLKKPKKMSMDITPDVDHGVLGSQAHWAQAAPSQYHLPEQEHMRASKRWLDIREVLSAAALEAVQCMSIALAPVAVPGLRRLPRLSTADGLTRKFAINVRVWEVKEEKQATDRKWKRSWVLVILLDLMTYQIECTCVQEAAEGFWRVPHKFQLILEEHAVITEVNEIINVLAVVVHVGWVMKGGPVKTGCMELCMFDLFQNMFKQAENRVIRIKGVVVDMLDGPCLKTQKGHIWFIFQDRNLGYKRLMEWYKDADPKEWQTITGSFSADGFPESDITIPNETIMIKAVQVPKLGLTLKKTFKVITKVLIEDYKDYLYEDCPYEDCNKKTPTGNVYVCPTCDMPYIMPGIKFRLNVEIEDEMGKQWVNTFNGACMGLFKQSALQMHTWQDSKEATTMNILPIPYKKYAIVIHHKSDEFGKKKGHPTWIALKFIEIMERCNKFGIVSIDGSLNVFLVQVALALIKKQMRKGNREQTYSKPVRHGSQNNMRANHAPERETDTWQEEHGHHGRMVERCQQQYWDEGKTDDASRLDDQAHDPLDLNGWMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQT9</accession>
    <name>M5FQT9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase SET5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">SET domain-containing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_82463</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
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                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">DJM-731 SS1</strain>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="445" mass="49707" checksum="B4EADEA1F086122A" modified="2013-05-29" version="1">MSSAVSPPDDALIPVVKTLRASLPTLGAAKLLAVLLTEHPEWTVSEKRFKKLLQTEGLALSGGAVGATNDKKIKNTDTKTNKYPASKLNPHLDITTFSDKIDAVFISPQKGKGLVAKLPIAEGEALWREDPFVHAADWDVFDLQQSGNACQYCALPFIPAPPTLAVSCPAISHGCNAAFCSRLCLTRAQQGGHSLLCRGRNPPSKDLLDFARKEQWRAVIALAVAVAKIMTAFERSDSEGQDMLEAWGTFATLDQEDRAKTLPEWEFTQERHRALWNMDYDHFVTTLCPPETDKAAQTRLRKIVKKTLSEDVRTELFSYRGFLRGLGRVSLNLDSHGGLFLLHSHMNHSCIPNMAVKHPPAAQAQKYPSSRIALVANRDIQPGEELTVTYVNPTWPYRRRKEELKEWGVECDCERCEQEKKDEPEEEEDEEANDLARELRMSFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
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    <name>M5FR39_DACPD</name>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">DACRYDRAFT_118846</name>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
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                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        </location>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="177" mass="18939" checksum="4CD3194A7DB03391" modified="2013-05-29" version="1">MSQNFRSVKEAEHNLPPKRKSQPIARVKPPGSKISFDMFIYALAFITLVISLFYAYRLTTWKTQAGGWINLLFDKHPNEPLISTNSPPGTSGLSLEAQIRNLADELGIHPRELAGAIKPLLPAATSSSIAAANPSGTVVNVFVETEPAGATAASVLEKVTGMAGMVGNDEAFLDEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR69</accession>
    <name>M5FR69_DACPD</name>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="179"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
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            <end position="240"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="264" mass="29015" checksum="84F4740E2A46D45D" modified="2013-05-29" version="1">MFGGSDFKPKSIFFHTTIMGSQNQGDRMQIDLNVPCDVEALRADREVQGRFIAESLQKVEGEMKYAGEWTCFACGKQAHELVHHPMSWLQAQPGFVMDYVHMVCSREEPKCAGVIEESNKELTTEMGMEPGAAGGESGDIPQEAPGAVAQEPKAEGKEKEVEKGNDSQHPSSAPPAGGCAVCHKQGKTLQCSRCKTIRYCSPECQKTDYSRHKGVCRWVDNVERSFASEKKEEGENKTGGEDWPAGIPRPFDPPAPAEHDHSNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR92</accession>
    <name>M5FR92_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">VHS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_117812</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in the regulation of membrane traffic through the trans-Golgi network.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626508.1">
        <property type="nucleotide sequence ID" value="XM_040770461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR92"/>
    <dbReference type="STRING" id="1858805.M5FR92"/>
    <dbReference type="GeneID" id="63685523"/>
    <dbReference type="HOGENOM" id="CLU_017092_1_0_1"/>
    <dbReference type="OMA" id="SAGMYPQ"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14235">
        <property type="entry name" value="GAT_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16998">
        <property type="entry name" value="VHS_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000008">
        <property type="entry name" value="VHS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="7">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="8">
        <location>
            <begin position="184"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="400"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="56451" checksum="F26B53645802E326" modified="2013-05-29" version="1">MLAQSFQQQASPVQLYVDRCCDPTLLEPNYALNLELAGYITQKKANTPREAAMAIVRYVNHRNPQVNMLALTLLQTLVQSVGYPFHLQVATKEFLNELVRRFPERPPPYPGPVMTRILEVINDWREGICKESRWKEDLGNIRDMHRLLGFKGYRFRDLPRGTNRSFVPTTENLKSPDELEEEDREAQAAKLQELIRRGTPRDLAAAQELMKIMAGANPDAKPDYRSQTLKELEKVQQKVILLNDLLNNASPGERFAKGDAYDQVATICRQARPKIQKWISDAESASSEDPHVLETCLELNDLINSVLNRYESYLRGDFSVQGVEIHGGVLGAGSPPPEPAAAKPIDLISLDESEQHSAVPQTSGSDDLAGLFGPAPAAPVQAAAHHPFTPAQITSLYSQGSTTRGMHTPQGSLSGFSGSDGFSPQPQNQASPAHPGFFNLHTMSVPQGSSRTGTPTLTGQQPQAQAQQQHSGLDAFGPFNSPPMQPMQPPTAPAVPAQNGGTGKGKDPFADLEGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRB7</accession>
    <name>M5FRB7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_82071</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the NRAP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626548.1">
        <property type="nucleotide sequence ID" value="XM_040776550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRB7"/>
    <dbReference type="STRING" id="1858805.M5FRB7"/>
    <dbReference type="GeneID" id="63691612"/>
    <dbReference type="HOGENOM" id="CLU_003502_1_0_1"/>
    <dbReference type="OMA" id="DERAHIP"/>
    <dbReference type="OrthoDB" id="10251401at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005554">
        <property type="entry name" value="NOL6/Upt22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035082">
        <property type="entry name" value="Nrap_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035367">
        <property type="entry name" value="Nrap_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035368">
        <property type="entry name" value="Nrap_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035369">
        <property type="entry name" value="Nrap_D4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035370">
        <property type="entry name" value="Nrap_D5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035371">
        <property type="entry name" value="Nrap_D6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972">
        <property type="entry name" value="NUCLEOLAR RNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03813">
        <property type="entry name" value="Nrap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17403">
        <property type="entry name" value="Nrap_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17404">
        <property type="entry name" value="Nrap_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17405">
        <property type="entry name" value="Nrap_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17406">
        <property type="entry name" value="Nrap_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17407">
        <property type="entry name" value="Nrap_D6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Nrap protein" evidence="7">
        <location>
            <begin position="187"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="8">
        <location>
            <begin position="330"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="9">
        <location>
            <begin position="501"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="10">
        <location>
            <begin position="689"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="11">
        <location>
            <begin position="885"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="12">
        <location>
            <begin position="1056"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT99650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1211" mass="134205" checksum="EA4743E7EE2CE19F" modified="2013-05-29" version="1">MPTEVTDEGIDIEEGEEDEDEDGNADDDEDDEDDFDDEFTSEAQAPSALVFTAPPGQRGPTTQDLVQLREATLLFNSNTFKLSLDAFLPTLRPSESRKPALTAFLHKLRTHLLSIPSIRPTHPLQAQRLPELNGVKVPYPFPRPAQEVNWKVLFLPPVEVQVIGSWATNTSLSIPARGNKSKHGWAIDLGIVMPPEMWEKKDYLNGRAWAKRAFYAAVVAASISAGGLDVQAQFEAPGGDERLVRVVLKATHGPDAPLSSHFAIHIHLLFPSGSAFPFSIPHLSPSRSCFHMQASAFSLPTPLYNSLLVSLSLPLPLLVTIHQFTQDIPAYRDALALLRAWVSRRGFDRSSRTGERSVLGFEGRGAWWALLLGGCVQGWEEPEKRSLGVTAKARLARGMSSYQLFRGVLDFLQSWDPARPVFMKSRTTSNSNKSNFTVDEWTQHHQCVFVDPSGSCNLLSGVPRSSLLLLSHEASLAMRVLDGEAEDAFGALLLRDLGLPLTRFDAVLRVDISGALPITDLRPAQLDNASPANALVHSILAVVERGLSTRAKCVTILQSPLPSWDPTTDRPIPNSSIDIGILFNPGQFARLIDHGPLADDTAGAATWREFWGDKSELRRFKDGSIQESVVWDASSHEDRSNISSRLVVYILGRHFRIPESAITLFQPMLDEFIQLPGSAVQAITGEVPSAIGFSTVLQSYDQLVKELKAIEGFPLSLLNATAATEGLRYTSAFPPLKVDASRVASLPDCLRHIPAHEIILEFEASTRWPDDLVADQKIKLAFFEEIATKLKARIPDSVVHIVLDPPPALPIEDNCILEVIMPNGIAFHARIYHNRERTLLERVVGDRAATDKERRQAASVLQRFNERFIDKPRHHSAIATLHHKYAVFSQTVRLTKRWLAAHLLLPHVPVELIELLCAHLFLCPGPFSPPTCLLNGFLRVLHILSTWKWVQEPLMVPLYSSKDAEQGARVGFPKEKRDAVSEAFSVCRSADPSISTRAWFIATEEDLNGMAWGHNAPTALICRRITQLAKTYHDYAEASFEKDNLQMRTLFNPPYDEYDFTLTLDPGVLPNLYQGLKADESVWLGRMKFRNLPNQEPPIYGSILKADFDPALRFFRDLQRIYGDVCVLFYDPLGGEKIAGIWNPAVLKPTPFKVLLGFSSMPEAHSEDDGEANGPTNGAKKSKATVSLNKDAILNEMAALGSGLVKSVTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRJ4</accession>
    <name>M5FRJ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624512.1">
        <property type="nucleotide sequence ID" value="XM_040773954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRJ4"/>
    <dbReference type="STRING" id="1858805.M5FRJ4"/>
    <dbReference type="GeneID" id="63689016"/>
    <dbReference type="HOGENOM" id="CLU_031719_0_0_1"/>
    <dbReference type="OMA" id="HGAFMSQ"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000053">
        <property type="entry name" value="BZIP transcription factor AtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021755">
        <property type="entry name" value="TF_Aft1_HRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11786">
        <property type="entry name" value="Aft1_HRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="458"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="267"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="534"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="603" mass="63363" checksum="D0509466AF5B15E3" modified="2013-05-29" version="1">MAVALAPRPMTPTSNLRTGAEIKTETTSDKSTPPKADGAAAAAPAPVRPPNKPSQSLRLEPNPFEQSFSQSSTSLPKLADARSNGDRSPRLPALKSPRLSSSPTDGAKSLTTPKPILPPVAAISSPSTGFEWQSGDLSSLRSGPLSPAMLAGPRERPTPSGLTPFVGGEFRSGLTPDVGRTGLTPLVGGPVSFPPPSPNTAAFLAMVTNGANGTNGLQGPEATITPNTLNALTGVLNGLSTNNVPGGPGNDNLHPNSAANQQHATYANDPKYGNYYPPAGADPRTLPSGQQAPAPAPVPGQQPVNGQNGYAPAASSATAHAATGLFLLSQAHQELTRREEMERLAQEQAAQQQGGENGNRMRRMSTISASTNDTQSPVVGKRKSSDGHNGPVPQQQTNGRAQQAARPSKRAKTTKNAKRHTSIEDDELGGDDDEFDDDEMMGGQSQGTELVKRPETDEDKRKNFLERNRQAALKCRQRKKAWLQQLQQKVEFLTAENERLHASLGGAREEVQRLTAALVSHRDCPLHPPSGLPQSHAISHPHLAQHPGHSGPAMNSGMPPHHQPAQYGPPMQHQGVTPPHGPHAAISVPVPVGAQGRGGGFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR5</accession>
    <name>M5FRR5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_84738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="GeneID" id="63691759"/>
    <dbReference type="HOGENOM" id="CLU_1932512_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="131" mass="15149" checksum="F14375EEC4CDEA55" modified="2013-05-29" version="1" fragment="single">MNILFHFVCICICYVVFFCWWTARPHDTRIPVTVYTAQHYPRATGRLSPFWKPQSPSSQHGIPLSLSWKTFSGCARPFLPDQGDHFACTKGRETQPRRSSRFPLSSFSLRRANNKTQPGIPRQIPHAYQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSD8</accession>
    <name>M5FSD8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773641.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5FSD8"/>
    <dbReference type="GeneID" id="63688703"/>
    <dbReference type="HOGENOM" id="CLU_2628509_0_0_1"/>
    <dbReference type="OrthoDB" id="10624744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067128" evidence="1">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="8132" checksum="F07F69BC4D69D787" modified="2013-05-29" version="1" fragment="single">MAPLAYFSALISVTLAISSGTLAQSFPRQTTSNIGCIPPTAILSQLSSRDNVERAAADSLPCSTTCFNGNYQYAATAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSX9</accession>
    <name>M5FSX9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_90967</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSX9"/>
    <dbReference type="STRING" id="1858805.M5FSX9"/>
    <dbReference type="GeneID" id="63692047"/>
    <dbReference type="HOGENOM" id="CLU_047850_0_0_1"/>
    <dbReference type="OMA" id="WYPPPGH"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="3">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT98424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="459" mass="47435" checksum="13B7EA12F2AE5CBC" modified="2013-05-29" version="1">MADNFIGARISLTSMRGVRYLGTLHSFSKDDSTISLSDVLSMGTEHRRPQNEYIAPSERAYPFIVFRVSDVADVSVEQPAPPQAINQVPEDPAIVAPGFPPGPSGVGPLPGGRPLPQAPGQPLPAPSQGPLPVPAPAPHAPIPASQPIPVPPAPLAPAPVSQAQAPTTVEAPKPRHPQPKGARVPSRSRSGQAVAVNAESASVRAASASLENVERALEGLRLERETEARQGPPSAGHKGPPPSANGASFPVRPANGTAAGEGDTRARNRRRTRPPHPTSGTFGTQTRAPLPAADFDFSAANSHFDKAALFADVVGDEEGSYSSDLEEGEEGEVESGTKSPGEGKDAGGKKLKSPVYDKSKSFFDQLSEAAPPSSGPDPAHAPAAGRGRGGSRGRERREQERNLNMTTFGEAGVGRYGDGVKVGLGMGGYGWRGGRGRGRGRGRGRGGPRGAPAQAPVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSZ5</accession>
    <name>M5FSZ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_83004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
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        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
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        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
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    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="237" mass="26815" checksum="6B764F37ABD5FE09" modified="2013-05-29" version="1">MTYTVFGYGSLIFKPPPHTIHQRPGYVKGYVRRFAQSSWDHRGTIKRPGRVVTIIPWGEWHTLAEERRHEEAADKEDIVWGVAYTIDPQYEDEVRAYLDYREKNGYSVHTEDIYNLVNGKEELIIPQCILYVGLASNPSFVGPEPLDYLAHRIWSCTGPSGANRDYLYGLAKAIRELAPGSHDVHLASLETRVQSLEVDERAGLLLLPAGEDVADSNMEEPQGEQFAQVAIMVNEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT39</accession>
    <name>M5FT39_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_37727</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627623.1">
        <property type="nucleotide sequence ID" value="XM_040774435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT39"/>
    <dbReference type="STRING" id="1858805.M5FT39"/>
    <dbReference type="GeneID" id="63689497"/>
    <dbReference type="HOGENOM" id="CLU_001570_21_4_1"/>
    <dbReference type="OMA" id="FYFFADA"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7928" checksum="1E4E7B7E40EB1089" modified="2013-05-29" version="1" fragment="single">NYPPGPKGNPVLGNLLELPRTLLFLKLSEWAKEQGKVNTYAVSTPTLVIINSAKVAVDILDRSSIITGDRPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTK1</accession>
    <name>M5FTK1_DACPD</name>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625612.1">
        <property type="nucleotide sequence ID" value="XM_040776975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTK1"/>
    <dbReference type="STRING" id="1858805.M5FTK1"/>
    <dbReference type="GeneID" id="63692037"/>
    <dbReference type="HOGENOM" id="CLU_1427934_0_0_1"/>
    <dbReference type="OrthoDB" id="426865at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21486" checksum="EC545C3ADABAAF4F" modified="2013-05-29" version="1">MLSGEGRPRLIFKDRDGQQMRFFVDAGGNIDSNTRRTSIRKIQRRGGLIVLSPLEAQYIIVWDDTSDGQLYARTWSGEGKVVLTLEWVNKCVRDEIFLGPTNDYGGCRVSITDGAIKPLANEQPFEDDEEYVHRITTCLPLPQSPFPGRPSPFPLRHLLCLPRSFLSTSLNPQCMAQTSRLADIYRLLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTK3</accession>
    <name>M5FTK3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_118516</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the midasin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625617.1">
        <property type="nucleotide sequence ID" value="XM_040770591.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FTK3"/>
    <dbReference type="GeneID" id="63685653"/>
    <dbReference type="HOGENOM" id="CLU_000050_0_2_1"/>
    <dbReference type="OMA" id="ILEQWHR"/>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000142">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000712">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001368">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040848">
        <property type="entry name" value="AAA_lid_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012099">
        <property type="entry name" value="Midasin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041190">
        <property type="entry name" value="Midasin_AAA_lid_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17865">
        <property type="entry name" value="AAA_lid_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17867">
        <property type="entry name" value="AAA_lid_7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010340">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="13">
        <location>
            <begin position="4788"/>
            <end position="4996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="800"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="4190"/>
            <end position="4252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="4269"/>
            <end position="4575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="4590"/>
            <end position="4621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="3009"/>
            <end position="3036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="800"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="4218"/>
            <end position="4227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="4228"/>
            <end position="4237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="4295"/>
            <end position="4308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="4339"/>
            <end position="4350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="4442"/>
            <end position="4457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="4481"/>
            <end position="4494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="4520"/>
            <end position="4544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="4601"/>
            <end position="4610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR010340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT98719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="5003" mass="559773" checksum="DCBC724D5B47C6BF" modified="2013-05-29" version="1">[encoded data, 5003 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTN4</accession>
    <name>M5FTN4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_57180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625672.1">
        <property type="nucleotide sequence ID" value="XM_040775421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTN4"/>
    <dbReference type="STRING" id="1858805.M5FTN4"/>
    <dbReference type="GeneID" id="63690483"/>
    <dbReference type="HOGENOM" id="CLU_004542_5_1_1"/>
    <dbReference type="OMA" id="MSAYHSY"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF117">
        <property type="entry name" value="BETA-1,4-XYLOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067170" evidence="4">
        <location>
            <begin position="19"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="5">
        <location>
            <begin position="699"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="777" mass="83520" checksum="D271288ADF58B067" modified="2013-05-29" version="1">MLATVLGCLVCAALGSLATDEIPLYKDPNAPIDARVTDLLGRMSVEDKVSQLIQGDIDGWMNMSDPLDNTLVYNATGLVEMMATKSGVIWAGYQMPYEKSIFAVTVGHKYLMENTTLGIPALIQSESLHGFTNNGTIFPSSIGMACSFNTDLMYEVAKAIGGEAEGLGFSMLFAPVLDLSRELRWGRVEENYGEDPFLTGEMGYAYVTGLQAGTRRNVSSTASARLAATCKHFAAFGSPQGGLNLAPVSGGERELRTTYLKPFYRACVQGIMSAYSSYDGIPAVANSHLLTEILRDEWDYQGFATTDAGSVDLLITEHGVASDRAAAAKLALENGLSGEMGGGSYTYLTLPESIANGSVGIGYLDKAVSYLLKTKFELGLFENPYPYPDYATTIRTPSTRHLLHQIERESIVLLKNDGVLPLQKGGSVALIGPSAGQVLGNSDYVFFNASLNGISPLQGLTDFLSGSNTTINYAEGCKLWSNDESGFPAALEAAEQSDVAVVVIGTWSRDQTLLWQGLNATTGEHVDLSSLSLVGAQLRLVQAVRKVARKLVVVFVSGKPVAEPWVKAWAEGVVQQFYPGELGGTALAEVLYGAYNPSGRLSVSVPQNVGTLPAFCNYLKGGRPVDPGFITPNGSLVFGHQYVLSTPLPLWSFGHGLSYSTFHYTALSLSHSQLQVSDTHTHLGVNVTLTNVGPWEGAEVVQVYLVIGVSGVVTPNQELAAFRKAFFAVGETRTLNLEIRMEDLPIWVKGWVWEKGEYVLRAGTSKNVYLNASFVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTV8</accession>
    <name>M5FTV8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627998.1">
        <property type="nucleotide sequence ID" value="XM_040772998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTV8"/>
    <dbReference type="GeneID" id="63688060"/>
    <dbReference type="HOGENOM" id="CLU_786555_0_0_1"/>
    <dbReference type="OrthoDB" id="3380644at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="353" mass="39649" checksum="388628E7A4C33DB5" modified="2013-05-29" version="1" fragment="single">MDILTQMTTYTVTGAIMGQWLLGMSTMITAILLFLLSYVRAASSHSSVRIFGWLPRELLGQAGIAMGLTLFDYLYFIFRNMRCLDGIVNNDQTNVALAMYYLDATNWRFIGSVVTWEWKTAFADCVMLFRAVKLFRNNDRLGGQHGYFGVLALLLLLYLGTIAAGIVTWVGLFRPAAATFDDLLEHSATFFMSIHCGYNVLVTLLISFVYWRAMSHQFKMMTVAQIALRSFSAGNMLYTIVITVLVVLYQKQLLFVYFWYDITQPLMTMSFTVPMLLTAFVRILPIASSMKSTNMNAVRPAAAGISVSMRREHNLEESLGTDGSSSLPMSSILTVQDQAKEKALESQDDLKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTZ5</accession>
    <name>M5FTZ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GIT Spa2 homology (SHD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_102761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623574.1">
        <property type="nucleotide sequence ID" value="XM_040767664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTZ5"/>
    <dbReference type="STRING" id="1858805.M5FTZ5"/>
    <dbReference type="GeneID" id="63682726"/>
    <dbReference type="HOGENOM" id="CLU_006748_0_0_1"/>
    <dbReference type="OMA" id="CRNHASS"/>
    <dbReference type="OrthoDB" id="5588096at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005826">
        <property type="term" value="C:actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902716">
        <property type="term" value="C:cell cortex of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022018">
        <property type="entry name" value="GIT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12205">
        <property type="entry name" value="GIT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="4">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="4">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="510"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="926"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="586"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1136" mass="122847" checksum="9EAF2274353E01AE" modified="2013-05-29" version="1">MAARGLNPPPSPSATAYSAASGLSAYQSQYRPPYSQQQQPPMPSMQGQMAMGGMGMQPMQSMNGMQMGMQGMQQGMGGMPMGMQPMQGMQSMQSMGMQQPAGGMQGPMSPTSPTSGQNSQANYEKFQGFHEQLRKFLASEDVKEVPGARADPRSKLVKLNEAQFMELSTDVHDECLRRNSPNPTPFLPLRSELHPKRNQARQKLATLSKTKFRDLASDIYFELGRRFPAFKGQDRPETPTSTYEDSLASQSQAYAATTHTTGSSSTTTAASLSIPPSQSDSASGSTRGTTPTSYSKLDDPYSQQRGPGYPLEDNQPRMRRRPSETGEALPRQSGESTRTTGADPSVWRRPSDRSAISAVSAADRRRPSVEQFAFRSNQTNAPGYQGSQQPGGTNGTGSQLPYESASFAPPPTSTATLGVVNPMKSTMAEEEIEVPYGRDDAEDRPGSSASASDERDPYRGERLLVDEEEEEEGNRSPILTGPSTATLREGGLSALAGGFGVREYENAPDKVARAGARGESDRVRVELPDDAGDDGDGDGDEASTASRGVSEFYDKMSFGRVSVASSGGVGHRKTGEREGVEVEKLRREYELKIATMNNRIQSLEAELSEVTRSRDGSVQQLQAVREETVKVRDLANDQASQVAQLKQDLEDVRAARDREAEDAAARAQQAEAELELVRESFEQFKFDHTNKQTEAGPLADALRSEVQQLVTELTELSERNEEMMHEKDSDASIIRDLNAQIKEWKRKYENAKTELRHMKATSTLSGPQTPKVSAAGGDGDMNHLPTSDTGAIADVHVTAFQSSIDTLLAAGRSSQPTSVLSAMKNVVTAVAAITEDVRAFEARPRRDKGPVDDDAVRALKDRASATLNNLVMASKNHGTSYGLSPVSLLDAAASHVSSTIVEMVRLLKIRRGTRNFLERAGSNKSIMSPLKDAPEQRFGRSSSAASAGRDGGSGAERNSGPSPIRTNSKRRSDSHNGLPTPDRSTPTNSSLQYLPLDSTQHRPPIPTMRDEEAVPTEGSDDAWAELKPYLEAQSESIVHHIQTVLSGIRSGAKASELNEGLTQIITIVSSIVAVCKDSLPTASARQGQELLRELSEHCNTLSEAQVIGGEVNKQMRQAMATASFGVAKALKELMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUG7</accession>
    <name>M5FUG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_118384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626017.1">
        <property type="nucleotide sequence ID" value="XM_040770572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUG7"/>
    <dbReference type="STRING" id="1858805.M5FUG7"/>
    <dbReference type="GeneID" id="63685634"/>
    <dbReference type="HOGENOM" id="CLU_506240_0_0_1"/>
    <dbReference type="OMA" id="WVEARIQ"/>
    <dbReference type="OrthoDB" id="3229878at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="62003" checksum="E936125536701143" modified="2013-05-29" version="1">MGKGFCYDGWYFLHIYFWNYYPGLEILASIPTDSDRFDEWAQSYKERLDTFLKSDTAKIDKERDRYFKDSDGREFVATRDPRRNTSDGHWHYMIDFDNLTFVVNGRPICSLPFMPIEDIFEGWKPNQSASHSMPYNHRYIFHRWPAKTPPVSVFSYEHVVKAEKEISVDELLDVGECLTPREKLRDSILQVLVGTFLNIYSPGDHLFWLPAFSDRKDIPLKLRRAAASSVFGPIFVYDLEWTYEGPDDALALTWLRADVFLWITNDLSTPESVHREAGASLSEIDKSIKRGTIFGILFSFFDVVLLRATLDGDKWDYKYTTTLPFLPKPLATSMATAGITSVARLSNRPNLWLSCSTSDAFAKCAVVRPVLTQPQRFPTEIWIAIAEFIYSPHSMVSFAAASLQCREVAAEVCRSCRSGWTRFLEPIPIDWDCCPRIEDLRREGATHFHFTTYLLYELGVLRKTTRIKPEFQYGMLLGVDDGGLRVVHLGSHLTGIHRHYPSGKTVARLAYLLKNGFMLWYSFPVDTHRDMSKLDLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUT1</accession>
    <name>M5FUT1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_109438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626911.1">
        <property type="nucleotide sequence ID" value="XM_040768878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUT1"/>
    <dbReference type="STRING" id="1858805.M5FUT1"/>
    <dbReference type="GeneID" id="63683940"/>
    <dbReference type="HOGENOM" id="CLU_752316_0_0_1"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="195"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="50181" checksum="A14704BA49689505" modified="2013-05-29" version="1">METELNKLVAALCTSASVLQGALNDENVPNFRSDDPSPHPWDGGVPPPSAWYARKALVGLCYQIIALVQDPLERSIIDFTSFSLASSMNAVVRTQPTVAEVVLASGSDGIAVKDLAKNTGLDETKLYSLMHLLCTWNYFKEIEGGHISATRSTRALLPDSFVHGLSDSIIAGTAAASMLWEAAKTPSGSQHPSPFSLYHHVEIYDWIKARPDQIERFGRAMDTAEKTLDPGFILDLPVQDLGPNITLVDIGSGVGGLPMQLLKRNPGWKAVLQDQEILIPQMESFWKKDAPEIVESGRVTFLGHSFFEPTPLPPAPKDSPYVFMIKSVLHNWPDDLAAKILENLLPAAPPGTVLMIVNYTPAEPEPSKTTVEEFFRRINKHSMAEIQKAKIPLPDLLGVGWGFGDASVSTADMLMMLLMGSQCRTVTALKALLETTSWKFEGRTDYRGTTSVIKARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVA0</accession>
    <name>M5FVA0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cAMP-independent regulatory protein pac2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624139.1">
        <property type="nucleotide sequence ID" value="XM_040769364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVA0"/>
    <dbReference type="GeneID" id="63684426"/>
    <dbReference type="HOGENOM" id="CLU_639386_0_0_1"/>
    <dbReference type="OMA" id="WCTADAT"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="46607" checksum="E7BA1189BFCE6D53" modified="2013-05-29" version="1">MSAIEIRNAHEAHIVMEAVRLGQLPLISRRLSTKERLELIRHGAVFVWEESDYRGGVDRGGIERWTDGCKWSQSRMHEPFLLYEEKAEVPKEESEKLSGDKKGDAASRARRQNRPNKPDGLTKQTYSALLSPDAVPPGQKPAKWHLTCYFQRPNHTQLPLVEEDGPLSKIQPQAGTFVTAKGLTRRKSAAVSLDPADDALARLHTGSINGTQMGGGVSLRGLNGSIAETESDVSISPSVSTSPQSPYDMRYTAHSPWSGTSSLTGNSPLTPPAQYGVPHSPHAVAPHYSPVVMPQYQYPPHAAAYTHPASQPQLGPTSASPNSNFHMFQSSSRENLSLPPIRSTHNVQRARLPSVPVHPWCTADATGLGVQMPPPMTNGVTYGGTQGIPTGNSAIYDASRGCYVDTLAGRSQYHDDHRAWGPGVAIKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVA8</accession>
    <name>M5FVA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_84808</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624149.1">
        <property type="nucleotide sequence ID" value="XM_040776701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVA8"/>
    <dbReference type="STRING" id="1858805.M5FVA8"/>
    <dbReference type="GeneID" id="63691763"/>
    <dbReference type="HOGENOM" id="CLU_008926_1_5_1"/>
    <dbReference type="OMA" id="NWDSKTP"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22298">
        <property type="entry name" value="ENDO-1,4-BETA-GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067255" description="cellulase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="12">
        <location>
            <begin position="47"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT97251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="576" mass="61616" checksum="76DABD4D4A7A527E" modified="2013-05-29" version="1">MLPLSILLCITTLAQAQLSPSPTFNPPPPDAGTTPAPRQTIPNQQWSNLLGDLLYFYEAQRSGQLPSDNRVSWRNSSGLQDGDDVGFDLTGGYYDAGDYIKASFPLSWVLTSVCWGATVFGQGYDLANQTAYLDEMLRWGLDWMIKANPDNSTLFVQIGDDAIDNNYWGGDTNIPTPRPSFQVNDTNPGTDATAQASAAFSSCSFLYSGGVLNTTSSATAPTGIANQTYANTLLRHAAGLWDLSVHASGGMTEYSDTVPATADAYASSGYGDDLILAALFLSLATSSPSTYQQALFYYSQYKLSGSNGVLNWDSKAPAVYTLLAEMALARPSWAGSNLIGWQKEAERWMDGVSSGGRGGAYMTDGGLLYWPGDSDSASLNPALNAAMALAHYAPIASTSDKADTYTNFAISQLNYTLGDNPMSAVYVVGINPNSPNRVHSGMASGGNNINAIDTDPNGPDLHVLYGAVVGGPDNKDRFWNFRSDYIESEPALDYTAPLLTLAAYSVMNNPTDPYFTALQAGAYTLPPGHPCDDAWPCHSGLSEGGKIALGVVISVVGTVLVACIVWFVWRMRSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVD6</accession>
    <name>M5FVD6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIIE beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_23212</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627136.1">
        <property type="nucleotide sequence ID" value="XM_040773156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVD6"/>
    <dbReference type="STRING" id="1858805.M5FVD6"/>
    <dbReference type="GeneID" id="63688218"/>
    <dbReference type="HOGENOM" id="CLU_056580_1_0_1"/>
    <dbReference type="OMA" id="RTKKDNH"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07977">
        <property type="entry name" value="TFIIE_beta_winged_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="8">
        <location>
            <begin position="104"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="37010" checksum="6B3EE23B53B2D8A9" modified="2013-05-29" version="1">MSNLLRSTLQNNAKQQHARNLAPGFTIRKKESHTPHKNGASRPGSSVSSPSSGAATPKSSAPWPPTSSAPSAANSVASSAYSSDAEDGGVQKKKKQRLKQDVVFSQPADTGTGSHINTQLVYAVRALKDHGNPIRLEDLSIQLGIPLDSNAELYDMFLQHDRVIHDTKTNTYSYKPDFNIRNKEQLLTEITRHYKRGGGMSVKVIRESWPSAIPAIEELAARGDVIVTRTAKDNTPRIVFFNEVPLEQGGGQIDKEFQEIWNSQKVPDEDIIMSDLQSFGQQTASVEMTPKFSGGIRKKGRKGAAKPNRRIKITNTHLNKIAGIDLTKDYVPTTAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVE9</accession>
    <name>M5FVE9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Importin-95</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Karyopherin-95</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_23224</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627156.1">
        <property type="nucleotide sequence ID" value="XM_040773160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVE9"/>
    <dbReference type="STRING" id="1858805.M5FVE9"/>
    <dbReference type="GeneID" id="63688222"/>
    <dbReference type="HOGENOM" id="CLU_008296_1_0_1"/>
    <dbReference type="OMA" id="QQYQERW"/>
    <dbReference type="OrthoDB" id="10263328at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000027">
        <property type="entry name" value="Importin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="21"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="322"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00083566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="868" mass="95647" checksum="6A812274457FB6C2" modified="2013-05-29" version="1">MDPAQILANTYSPDASTRDDATARLEQAANENFPAYMSMLSAEVTNESRDQFIRNAAGLAIKNALTARDPKRQNEMSQRWLAVDANTRQQVKNNCFMALHSSNTRAGGVAAQDIAAIAAIELPANTWPELIEQLLGFVNNAANAGLRMATLQAIGYICEQVKPEILQTRANEILTAVVQGARKDEPETEVQLAAVNALYNSLEFVRDNFEREGERNYIMQVVCEATQSPSVPVQVAAFECLVRIMNLYYDKMAFYMERALFGLTVLGMRSSEPNVALQAIEFWSTVCDEEIDIIVENTEAEEYGEIPTRTCKNFAKIALNEILPVLLTLLSTQDEDADEEEWNVSMAAAHCLSLLAQVVLDDIVSLVVPYIEAHIKSADWHQREAAVMAFGSIIEGPSPKGLQPIVAQGLTVLIPMMNDAHPAVKDTVAWTLGKISDLMLSHIAIENFMVPLINAFVQGLDEKGRIAPNCCWGLMNIAIQLDPTDGDAESTPDTSPLSPYFDGIVNALWRVTDRRDNDHNIRTTAYEAISTYIEHCNKDNLNTVGQLAQQLLVRMESLLSQANEILGTDDRNNWHELMSNICGVLISVTRKTGSNISHISDRMMTDVLQLATVASRTSTVLEDVFLVLGAAATSLEQAFLPYLNAFLPFLLASLKAHEETQLVNVAVGLIGDICRALGDQCLPYCNAFMTALIENLQSDTLARSVKIPILQAIGDIAIAIGGNFEHYLSTIMEMLKQAGAMEADPLDAALQEYVVRLRDGIIDAYVGIVQSMRASHKENELLPYIPSVFIVILKCLNEDEYDRSDTSTRTLLGLIGELAVMYPNGQIKEYLLNDAVVQTLKYTRGRSKITKATAKWAKDAVKKATTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVI1</accession>
    <name>M5FVI1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_84887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624239.1">
        <property type="nucleotide sequence ID" value="XM_040776707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVI1"/>
    <dbReference type="STRING" id="1858805.M5FVI1"/>
    <dbReference type="GeneID" id="63691769"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="36405" checksum="4F83D4BB497C7118" modified="2013-05-29" version="1">MDYGIPPLPPNTSLASRSFLITGATSGLGYATALMALQLGASPVYITARDVSKGTSTRDSLLADPVVKENNPNAKVEVYALDMARWEGVLGFADKFIDDRTASGEGLDIAILNAGMFSIEYELAPTGNEMSIQVNHLSTSLLALLLLPLLEKSSTPDHTSRLTFITSVQHMTKYGRLTACPPDNVNYLESLNDKATFDRTQRYGVSKTLLIYIVQHLATHVSPDKVIINNLCPGAIYTSINRNMPIHSWPLLAWMWRHGNTPEAGARTYIQAVAVLGKESHGKWYQRGKHRKYGDFVRGLEGQKMREKEWKETMEVLEKVRPGISQVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWE2</accession>
    <name>M5FWE2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629133.1">
        <property type="nucleotide sequence ID" value="XM_040768424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWE2"/>
    <dbReference type="GeneID" id="63683486"/>
    <dbReference type="HOGENOM" id="CLU_2654455_0_0_1"/>
    <dbReference type="OrthoDB" id="2122304at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="76" mass="8149" checksum="43E0DAB4C6051B4A" modified="2013-05-29" version="1">MSPLPACGVKHNNLKPREMESAARNAGVSEPVLAKYRHLSASHTNTLESFPILVTALVCGNFAGLRGRVMNIYALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWY0</accession>
    <name>M5FWY0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624864.1">
        <property type="nucleotide sequence ID" value="XM_040773892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWY0"/>
    <dbReference type="GeneID" id="63688954"/>
    <dbReference type="HOGENOM" id="CLU_2831152_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="66" mass="7420" checksum="79ED5073E35B87FE" modified="2013-05-29" version="1">MSARGNSSLRNLYGQSVHDFREATVTQAVWAKVEYSCDPTMPNPVGASQGIVRIQDTFHFEWSMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX35</accession>
    <name>M5FX35_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629445.1">
        <property type="nucleotide sequence ID" value="XM_040771087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX35"/>
    <dbReference type="GeneID" id="63686149"/>
    <dbReference type="HOGENOM" id="CLU_963187_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="289" mass="30811" checksum="B3E7C1734BA1ECC0" modified="2013-05-29" version="1">MLLEVTRPDGVAPQAPTPKPVQADGTRPKHEPLARRLAQRRRADYLPMTPSSVSGLPPLPVPETSASDGEEGQFDDAPTSPHVAPTANASQDQVQSKDGSSTSQQSSPLARLPVKLTPWEEEQRRLAQELSLRQAGDALDKMNATQGDVAERTWKPQRGMYKQARSQALREDSQRQPRVRGEPPQQQYVQEGEGPRPPLKRLFGPRSRSEDAGMGRGAPSSRGKQLFGPGARRPLAGRTGITAGEGGPGDFPSGPNVAPAPAAVPAVLGPLDPSALPFLALSTPPPLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXI0</accession>
    <name>M5FXI0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629605.1">
        <property type="nucleotide sequence ID" value="XM_040768331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXI0"/>
    <dbReference type="STRING" id="1858805.M5FXI0"/>
    <dbReference type="GeneID" id="63683393"/>
    <dbReference type="HOGENOM" id="CLU_2003833_0_0_1"/>
    <dbReference type="OrthoDB" id="3231112at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="13894" checksum="0CDC762512F93A46" modified="2013-05-29" version="1">MLKWKPMNSSPLETWIHKSGKVVLSGDSCPSMPSCRAQGAVMAVEDAGVVDSLSTTLSSSSTWRSFYTYMRTHETKDADMHPAMEAEMSGDVLEAEGSQNEWADRKACRVQFGHDAKWMWRDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXI6</accession>
    <name>M5FXI6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629615.1">
        <property type="nucleotide sequence ID" value="XM_040775013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXI6"/>
    <dbReference type="GeneID" id="63690075"/>
    <dbReference type="HOGENOM" id="CLU_2164337_0_0_1"/>
    <dbReference type="OrthoDB" id="3257409at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="121" mass="13746" checksum="CF5ED11DB2012BAB" modified="2013-05-29" version="1" fragment="single">ELSARDQKRFKAFHTKMEAHLMIAQYKVLQNASPEVFPPLSKVLWHVNFISAIKTVSYDCCVNSCVAYTGVLTKETICPHCSEPCLKPNGQAHRQYAYLPLIPQLQVQYGNGRCAKLLMLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXP5</accession>
    <name>M5FXP5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629695.1">
        <property type="nucleotide sequence ID" value="XM_040768353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXP5"/>
    <dbReference type="GeneID" id="63683415"/>
    <dbReference type="HOGENOM" id="CLU_1023156_0_0_1"/>
    <dbReference type="OrthoDB" id="3413923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="30015" checksum="6309C69D0E253635" modified="2013-05-29" version="1">MAIWMQHDVCAALSRPSHARSYVMSVRLARMIGSDISIEPITLFTSEPGHALLHCDAVTISDGTRNIIISQKYSSLSFVLQVLWNVDTTMVDAVEALESPTIAVSTNKRHITEEKRDLPALQRAITMIKWGICMRQCPSPSLRRGTLSRMLVAEDRLPDTYRVDIEDVARQYYKFPDGGLQALLCGADVPGIPQVVAFSVGRTIRGANVDKYTLLPGEKLRLADPTIDLERCTLNRDNLYADFATALDLAAVEGIDPTGVTLALKRFGISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY36</accession>
    <name>M5FY36_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625374.1">
        <property type="nucleotide sequence ID" value="XM_040770649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY36"/>
    <dbReference type="GeneID" id="63685711"/>
    <dbReference type="HOGENOM" id="CLU_071631_0_0_1"/>
    <dbReference type="OrthoDB" id="5311491at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="326" mass="36080" checksum="BA633DEE4BF6F9BE" modified="2013-05-29" version="1">MALDWKTATLAPVPGEESIHLRYFDTGVPEGVSEPYTTIIAIHGFSSNAGAWANSASIFAKTGFRFIAHNRRGYEGSSEYYEGPVKDAVGRYMLDLAGFVRFAVDELDIPSKDARGRGGIVLMGWSKGTASVMTLLSLLASPQDPPISLPKGLDLSPYLSVLYTHLRHLILFEPPGETIGLPYTPDYAAVIHSSKPFLQAFPEWLIPTVPEEKRHLLGKSTDVKNALKDFPVWLAERTDEKECARVAEVGLRHVPKEFGVGLVWCETSIQWCRDTGAWIAERLGDQPNTLVKTILGGHHFYNMTDSEEFVETIAGLIKELDTRVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY89</accession>
    <name>M5FY89_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625419.1">
        <property type="nucleotide sequence ID" value="XM_040773724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY89"/>
    <dbReference type="STRING" id="1858805.M5FY89"/>
    <dbReference type="GeneID" id="63688786"/>
    <dbReference type="HOGENOM" id="CLU_071116_2_1_1"/>
    <dbReference type="OMA" id="VIKPMAP"/>
    <dbReference type="OrthoDB" id="49520at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="7">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16801" checksum="9D9E609037CC5705" modified="2013-05-29" version="1">MAPKRPTRKTQAFPDTSEGNVEQTEAERLSFLHLPRPFKNPRYTRPQSKKLRSTKQILAAERERERLRRETGTANKEAPTYITIEAAPSLLPQKRYCDITGLEAPYTDPQSKLRYHNKAVYEFIKSLPPGTSHECLAIRGQHSVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYB3</accession>
    <name>M5FYB3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_60371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795895">
        <property type="protein sequence ID" value="EJT96517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623415.1">
        <property type="nucleotide sequence ID" value="XM_040775628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYB3"/>
    <dbReference type="STRING" id="1858805.M5FYB3"/>
    <dbReference type="GeneID" id="63690690"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="VMFARYL"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10744" checksum="1230371105ABD96A" modified="2013-05-29" version="1" fragment="single">RAATIDNSIPLSKPIDAEDGQHVHWIPVHAGQRVILNFDGFNRSEIVWGTDANVFRPERWLENVMSKVAPEDQCGGPYVNLANFGGGPKACIAWRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYD4</accession>
    <name>M5FYD4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_40927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
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                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11871" checksum="C9EC85385B8B5D83" modified="2013-05-29" version="1" fragment="single">RKTAPLVRVEHLQAHLTLLHVFHSLKSTVSATGAPDLTPEERWVTFVHRAVARFFTWGERVVSWRGPEVQPLKALEIPPIDVLMVWHAYLLNPRCYYEDCIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ00</accession>
    <name>M5FZ00_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_2120994_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067453" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12415" checksum="571AE41E6EC2CDCE" modified="2013-05-29" version="1">MPSFSVSLPPLCLLICSAIVPSPFSVLSPFSSRRDTDLSLAESLAKSSTNLLNVRSIFQRALFLFIGNIITTGSTWCKQCTRTERGSSCAAASAFAVPHASKAAAMWRFWPERE</sequence>
</entry>
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    <accession>M5FZA4</accession>
    <name>M5FZA4_DACPD</name>
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        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_116975</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZA4"/>
    <dbReference type="STRING" id="1858805.M5FZA4"/>
    <dbReference type="GeneID" id="63685355"/>
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    <dbReference type="OMA" id="YVHATCL"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="414" mass="46403" checksum="827B1B4B6CE173F8" modified="2013-05-29" version="1">MEFDDHEFHVPPPPRRPPSPTTSDRDDENAVENSVLLRRSHSPPPASPEDDRMCRICFGGVDDEPEMGRLIRPCLCKGSVSFVHVKCLNDWRRASRNRTSYLACAQCGYKYHFARTRVAGLATNPFILFLATLILFCIITLAAGSVMSYFLPPYLLSSTTDPQSTTKSPLLVKALLEEDDEDEDDFTTQLFFYTPAGAIQDVLESALRAFLSGDALRLMASFLGFSSNSKQIPIDNPVTGFKQTVRIGTETPLPIHVPPFLAGILQRLAIGTATIGILSFVNLLLSFSLLLPIQMGLRNVFRRGPRDSSATSTALIILFIIIGLGRAIHKVYKVTRILAGFILLMAETAILDVTQEDMERERKSIRACFQQVHLKFLVRRSWFYRLLKFEPAAWSDVRRAIRRGYEGFVEPQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZF6</accession>
    <name>M5FZF6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_82796</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625849.1">
        <property type="nucleotide sequence ID" value="XM_040776592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZF6"/>
    <dbReference type="STRING" id="1858805.M5FZF6"/>
    <dbReference type="GeneID" id="63691654"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OMA" id="WCAHEIL"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF4">
        <property type="entry name" value="CYTOCHROME P450 98A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="559" mass="63734" checksum="72A4AC64AC61BB1F" modified="2013-05-29" version="1">MTIIEKGIDLLALVGLQRAIRDVGTFQVVGALVLLAAVGVFVDWLWMYQLHKKMPPGPMPWPIIGNTYQLPDEKPWILFEELAKKYKTQVLTFWIGRNPTVWICDAWAASDLLDKRAGIYSSRPHMVVFGALGTGQNNLVTMTYGERWRLHRKLTHMGVGLQQVRNYKPFQDDESRIVAYDVLRKPEQYVMHFERYAASVVSIIGYGRRIASDTDPIITEVIAVMQRAAELNVPGKTFPMLLETFPILSYFPPEIAPWMHGLRRGGGRAYGFFYALAEEAATESKNHNYMKAIFDENDKNHLSKKEIASLSGNLFGAGSDTSSSTLVTFVLACCAFPECLPKAWEELDRVVGNARSPDLGDAPSLPYVNAFVKEVFRWRSVAIIGGQPHAPIQDDYYKGWLIPKDTWVQGNTWAIHHHSRDFPDPDVFDPERFLQGGKRNRPFPNEKGYMTFGWGRRVCSGQGLAEQGTWITVARLLWGFWIRKAVDEKGREVPVDIFAYTNGLNMRPRPFACRIQPRTETHRQTIEREGLQALEDLSVYEGETRYRMSTFYRENPSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZG7</accession>
    <name>M5FZG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630325.1">
        <property type="nucleotide sequence ID" value="XM_040772195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZG7"/>
    <dbReference type="STRING" id="1858805.M5FZG7"/>
    <dbReference type="GeneID" id="63687257"/>
    <dbReference type="HOGENOM" id="CLU_013838_0_0_1"/>
    <dbReference type="OMA" id="PIQSCFQ"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF90">
        <property type="entry name" value="CENTROMERE DNA-BINDING PROTEIN COMPLEX CBF3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="100"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="677"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="786" mass="88693" checksum="2C56C550292DAD52" modified="2013-05-29" version="1">MDTTDHDIAGSPNYEDMEEYYEDTPSTSISGGRSHHVPELPQPIKKKRRREALSCSECKRRKIGCDRKKPCGPCARRGESDMCKWSVLPPVDKPIGRSSYNALKDQLTSTQKVCKELQALCHKQADEMQALRSQIAAPSSPASSPAAHLQHKRPVGPLEQFQAQAESFKSARKDRARVASSYTHSSTSPPSTGNGGAPPVLIQASETLDGFPAFPDVDAGLGRSNQPEINSASDVWTGIPERWVCDQLTDFFFSDIEWHICMFHRPTFDSNYRKFWSLNTAAERAEVVNPQWMALWWSILCLALTSMGPEEPIKRGICVDRQTWKGMGKRFWLIAEQALRDADYMSSQNIETVQALVLSSYCNLSLDNQGYKSQAAMTALAIRIGMNQGLHRLGQEPHGVAPPKGLIQRELRRRVWWNVVFLDWNISTQMNSTYLIHPNQCNTAKPMNLDWDDMVEGRPLPTKPTVERTSASMLLAKVGLAGTVRELTDRINSMNGVLDSAYLPIHKAQQDALLRTLPMCWRVPDSALEDRMPVVRWEYLQFNLHMHNRRIRMHRPFMLDGYRDGTYHAHPSTGPCVRAAHAILVLFKDGQEKGFPGFYAWYNLMYCWMAAVILAMDAFYLPNEKVIGTEIQERSRNDYIMFAIETLERSNDISEIASRGAHVLRFLLAEAQKRTSAGAQNSPASSQSSHLSAGMGPATVQYQPQSNLRTVQDLQFPSTNVNGDYANISAEQAWMNFGDLQPDLLNELSMTMPSSNQITRYGNSTQHTLQWAQHMMRPHQPQQMMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G047</accession>
    <name>M5G047_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IF4E-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630525.1">
        <property type="nucleotide sequence ID" value="XM_040768141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G047"/>
    <dbReference type="STRING" id="1858805.M5G047"/>
    <dbReference type="GeneID" id="63683203"/>
    <dbReference type="HOGENOM" id="CLU_043552_3_0_1"/>
    <dbReference type="OMA" id="ICEYRAN"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="30336" checksum="2EE9B1CD231B4617" modified="2013-05-29" version="1">MASNGYFSNHSQQARGASTVVTPGSGSQTTTLISPMGIGRGKMVPALASVARRSGRLSLSLATDKFPADKPSTTISTAPLGDKTPHPLRSTWVFWFHHRPPGNKVTNYEDGIRKIASFGSVESFWSIWTHLQLPSRLTPTTDYLLFHSGVKRPVWEDPLNITGGKWIIRLRKGFADRMWEDLVIAVIGDQFDDEVCGCVLSVRTGEDIMSVWTRDGNDQRAIDGIKATIMKVLNLPASTIMEYKSNNDSLHDRGNFRHHLSTHQHHIHHDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G048</accession>
    <name>M5G048_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proline imino-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_25268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624050.1">
        <property type="nucleotide sequence ID" value="XM_040774091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G048"/>
    <dbReference type="STRING" id="1858805.M5G048"/>
    <dbReference type="GeneID" id="63689153"/>
    <dbReference type="HOGENOM" id="CLU_020336_15_1_1"/>
    <dbReference type="OMA" id="WGPNEYT"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="30"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="33155" checksum="927EA8F39C68168C" modified="2013-05-29" version="1">MATSSGKVTFRDSYETWYQVYGHLSTADVPPLVFLHGGPGVPGRYLLTIGDLWTTHGIPVIFYDQLGCGNSTHLPDKGADFWTVELFLEELDNLLSKLGIKDSYFLGGNSWGGMLAAEHGVLKPSGLKKLVIADSPASMELWLQAADKLLSELPPDIRRAIEENETNGTTDSQEYKDACNIFYAQHVCRVQPFPPDVQKSFELLEQDPTVYHTMNGPSEFSVVGTLKTWTIVDRVKAIDVPTLLINGKFDEAMDLVVQPFADGIRGARWITFPNSSHMPHQEEREEYMKVVGQFLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C8</accession>
    <name>M5G0C8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_35650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_2800901_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7784" checksum="9110159C6C4619ED" modified="2013-05-29" version="1" fragment="single">PFGGINVLFTGDFGQLKGAALHYSHQLLRQIMPQTSQSNKGQDALLGTWYWKQVKEVVILQWNVRQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0E5</accession>
    <name>M5G0E5_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_59108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="30839" checksum="F3F1A1EAC511647C" modified="2013-05-29" version="1">MFSRTTQPPEYTALALHAEDEPLTKDVDRDSDLPAQSGSDDFPPVQPQSQLLPKLVLYASLALALLSTVNVLLLPTTLHQYLSYPFSEQELKDLPFPDQRLGLDRAAAAIPPPQVYYRAWPDRIVRVSRKLKNAVYGDGVQVYVTVEDSTIMRFPVPEQGNACAVSWIPPPTYSGRNNDLTTKGDISEVEVWSVLPSPSSTNPYPGEGEIEYENISYSTLPRGELLGVLDLTQGPNSTTQEFACPRDGEALVVEFMCQRVACHVSFMQIEMEPKFGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0F2</accession>
    <name>M5G0F2_DACPD</name>
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        <recommendedName>
            <fullName evidence="7">Tim44-like domain-containing protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_107142</name>
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    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629106.1">
        <property type="nucleotide sequence ID" value="XM_040768418.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G0F2"/>
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    <dbReference type="OMA" id="WRAHAFQ"/>
    <dbReference type="OrthoDB" id="19619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024621">
        <property type="entry name" value="Mba1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051975">
        <property type="entry name" value="mtLSU_mL45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07961">
        <property type="entry name" value="MBA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="37212" checksum="4B6048095564C5B1" modified="2013-05-29" version="1">MSASLYKIGGICRRSCLQPLPHVRYYAAAGTTARTTSTSKPPSAADLEAQKQQKAIEKERRLVDISARQQNPFHDPMNTGIAIPLLAVKPPVSWSSLKGVSIRGRTRWLSDRVVDMFSNYTTILNLGRNQRLPFIKFSDQPVGWRNTWFGKRDVWLKPLQENALDMYIKTNEAIAQGDRNTMLALCQNDFLEDAIRRNKALGRGTKMEWKFHGEASPTKVLSIREVTMPTMDGSEVFLIHVLMRFETMQSLSVVKLPPPQRDSKGRRIAPTGGAITSQSPPKRVTEYLVLEGRSRQEIASWKFRAQLYDDSAPYISDPESGKTSEKGKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0K8</accession>
    <name>M5G0K8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_99940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629171.1">
        <property type="nucleotide sequence ID" value="XM_040777641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0K8"/>
    <dbReference type="STRING" id="1858805.M5G0K8"/>
    <dbReference type="GeneID" id="63692703"/>
    <dbReference type="HOGENOM" id="CLU_024205_0_0_1"/>
    <dbReference type="OMA" id="QVAMMLE"/>
    <dbReference type="OrthoDB" id="10050400at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="40044" checksum="68E6CA237C97E3FF" modified="2013-05-29" version="1">MVVIATAATAYALYDFYSAATTYPKSIRPELRRAIKAEHDRPKSAARWYRQAWEAARKLDASELGSSWPKKLSGLAIALATRLEGNKEFSEALQVMHTGWQDLEEPAKTDPEMRARRVAMASKMSDLAAAVGDAVIEEEWAVWAVEEVLRAGIEEKGKEKEKENADDEDLALPKWVGKAETASLLERLGSIYARQGHAEYAVPLYLQALGEMPLQVSPKNSFFSTSSQQATPTSLCQAAVLFNNLSELFAHRAAPNTAELKQALQWGHMAIEALKEASKMGLNNAEDPDGCRRTGVVVQTNQATLMEVHGDLRSAEVLFTSAHRLADQIRWGEAHNQAITGLERVQRAQSNSSSSPTPGKDARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0U5</accession>
    <name>M5G0U5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626349.1">
        <property type="nucleotide sequence ID" value="XM_040769019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0U5"/>
    <dbReference type="GeneID" id="63684081"/>
    <dbReference type="HOGENOM" id="CLU_1626987_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="18540" checksum="5009CB4C350C2491" modified="2013-05-29" version="1">MDDPPSSKWEKMVSKRIKEWRLGLDLSALDIIVTDQLNRLGSHGLPLTRELIGVGSSALIYRYTVPGRGSEPMSLVARVIYPRQPYWKTKAEAAVMNLVRARNVPVPKVYQCSLTASDNPVGAEWILMEYMAGERLDDVFDSPEFTMDKKKRVIRDLRSTSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0U7</accession>
    <name>M5G0U7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628652.1">
        <property type="nucleotide sequence ID" value="XM_040772711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0U7"/>
    <dbReference type="GeneID" id="63687773"/>
    <dbReference type="HOGENOM" id="CLU_2941659_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="60" mass="6906" checksum="E8A03AD11C974526" modified="2013-05-29" version="1">MLKRYLTVIRFHRILHQNTGVAYAERLEKKQMGKMQDGIAVEIIPVFSIPCLRASQTASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G122</accession>
    <name>M5G122_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628752.1">
        <property type="nucleotide sequence ID" value="XM_040772733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G122"/>
    <dbReference type="STRING" id="1858805.M5G122"/>
    <dbReference type="GeneID" id="63687795"/>
    <dbReference type="HOGENOM" id="CLU_983600_0_0_1"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="283" mass="31642" checksum="802A5B9214883A93" modified="2013-05-29" version="1">MPDAHTLLACVDLGGLVRLVWRWEGERGEWGYHDAMLLPAPLGTPVFPYSDIGEAIAALPRTPRTPETKEEEEEYGTIRATHAAAQAPAGYWGSRSPSPEREEGEGEGEGEGEGREDAYWSRYSQVGGTADSTVPSPVNPEKLLARSPGNREKEDSTTLEERFRRLERERERMDVDMRDVRELDERYEIPSHSQPRPREQEVVLNSGVGTPVKRYPPNGPTVVVADPHSHSYSSVHGNEGDKPLEDALRGLWHMFRSATDACDEGDGSRERFLRAARRVVDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G143</accession>
    <name>M5G143_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_52312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628782.1">
        <property type="nucleotide sequence ID" value="XM_040775099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G143"/>
    <dbReference type="STRING" id="1858805.M5G143"/>
    <dbReference type="GeneID" id="63690161"/>
    <dbReference type="HOGENOM" id="CLU_129084_0_3_1"/>
    <dbReference type="OMA" id="TQRHARP"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_bL32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="13751" checksum="461FA7884915BB68" modified="2013-05-29" version="1">MAALVTSVLLPQKPSPWSIVGLFKISTFQKRVTPLGFSTVLGAGLLQNLLDLFPPFLLAVPKKKVSHSRKAMRSANKGLKDKHNIVNCPACGSAKLAHHICQRCLGELNRAWKTQQKAGQGIFAGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1G4</accession>
    <name>M5G1G4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629463.1">
        <property type="nucleotide sequence ID" value="XM_040775032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1G4"/>
    <dbReference type="STRING" id="1858805.M5G1G4"/>
    <dbReference type="GeneID" id="63690094"/>
    <dbReference type="HOGENOM" id="CLU_006344_12_2_1"/>
    <dbReference type="OMA" id="WLERREH"/>
    <dbReference type="OrthoDB" id="3232941at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="28602" checksum="F0A6F2722FE5CEFF" modified="2013-05-29" version="1" fragment="single">GIHPIDHPFWESLPYTDTYACNTPNPLHELHKGVFKDHLFAWCLDLAGAEEVDAHFKWVPPHHGLKNFERGVSGLSQMIGTEHHHMQKTMAALLVGLPGNITSQTLHATHAILDFIYLSHLPMLTEANLQRMECSLAKFHVYKEAFWAASSCKDFHCILKLHKLQHYIASIQSHSPCNNFNTELPECLHIDMVKLGYHVGNKHDYIAHMMTWLERREHMHKYTQFLKWAERKHPDYFGDLGEGVAQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1K5</accession>
    <name>M5G1K5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_87393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630995.1">
        <property type="nucleotide sequence ID" value="XM_040776805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1K5"/>
    <dbReference type="GeneID" id="63691867"/>
    <dbReference type="HOGENOM" id="CLU_1713180_0_0_1"/>
    <dbReference type="OrthoDB" id="10518515at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="16632" checksum="659B509D75914E89" modified="2013-05-29" version="1">MTSMIPVEPTYAAMATSPTTGRKFFRRSSESHYNHPSDVGGAALQATTDPVTNAAMEEELEMEQEEEEGWVGEARRIWRRMSFGGTASKPAVEGKEKEKENKVPIIKPPVKAPAQPVAGHEHEHTHGPLASEGHAKGKEVPAVPETEEVPAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Q2</accession>
    <name>M5G1Q2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_54916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626699.1">
        <property type="nucleotide sequence ID" value="XM_040775291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Q2"/>
    <dbReference type="STRING" id="1858805.M5G1Q2"/>
    <dbReference type="GeneID" id="63690353"/>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_1"/>
    <dbReference type="OMA" id="AKWRAQT"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="5">
        <location>
            <begin position="13"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="6">
        <location>
            <begin position="410"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="466" mass="50336" checksum="40D72E9B99471C6D" modified="2013-05-29" version="1">MTDKFRIEKDTFGELKVPADRYWGAQTQRSLQNFDIGGPTERMPPPLIKAFGVLKKAASIVNMTYGMDARVGKAIGEAADEVISGKLIDHFPLVVFQTGSGTQTNMNVNEVISNRAIEILGGELGSKKPVHPNDHVNMSQSSNDTFPTAMHVAAVTEIRGQLIPALTELRDAMQVKQAEFEGIIKIGRTHLQDATPLTLGQEFSGYVQQLSNGIERVSDVLPRLSLLAQGGTAVGTGLNTKKGFDVKVAAEISALTGYEFKTAPNKFEALAAHDALVEAHGALNTVACSLMKIANDIRYLASGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAMTMLCAQVIGNQTAVSVAGSWGQFQLNVFKPVIIKNVLQSIRLLSDGCRSFTKNCVVGIEANEKRIHQLLTESLMLATILNSHLGYDNVAKCAKKAHKEGTTLKEATVALGFLTPEEFDEKVRPELMLHPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Q5</accession>
    <name>M5G1Q5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-aminolevulinate synthase, mitochondrial</fullName>
            <ecNumber evidence="5">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_25024</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="5"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624565.1">
        <property type="nucleotide sequence ID" value="XM_040773971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Q5"/>
    <dbReference type="STRING" id="1858805.M5G1Q5"/>
    <dbReference type="GeneID" id="63689033"/>
    <dbReference type="HOGENOM" id="CLU_015846_6_0_1"/>
    <dbReference type="OMA" id="ARRCPIM"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="16">
        <location>
            <begin position="200"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJT97667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="672" mass="71909" checksum="2BF7725FF9C599E6" modified="2013-05-29" version="1">MDRLTTRSLSKLRSSCPYLLRTPTSTLRSLSTTASAQAGLTRLAVTAQKCPVMGPALAVRAAQIGHPAKSAGPSKGCPFHAAQGKRGYASVAGRAEVDEIHKKAGVAAVPAQGICPHAAAGARAAAVDTPAPGTPVDSKAASAEQTHEHDGKAYDYEAFYRSQLERKHKDSSYRYFNNINRLAKQFPVAHTENTQEKVDVWCSNDYLGMGRNEVLLDTMHRTLDRYGSGAGGTRNIAGNGALHLSLEAELARLHRKPAALVFSSCYVANDATLATLASKLPGCVIFSDALNHASMIEGIKHSGAKKVIWKHNDLADLEAKLAAVPKETPKIIAFESIYSMCGSVGPIKEICDLADKYGAITFNDEVHAVGMYGPHGAGVAEHLDFEANAKAPDGERVPGSVMDRIDIITGTLGKAWGTVGGYIAGSHDFIDTIRSYAPGFIFTTSLPPATVAGSQASIAYQSAHIADRQLQQLNTRALRSELAKRDIPVVPGPSHIVPILVGDAALAKAASDRLLRKYNIYVQSINYPTVPVGEERLRITPTPGHSKAQMTHLINSLEEVFNDLSIPRESEWVRRGGRAGVGMPGAQKVNSIWTDEQLGLLDGTAPKMLDELPKGRAKIDERAAQIAEKRLEHLLGPSTRAIRFANPVEEHVRAPEVPVEILNEAGLGSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G272</accession>
    <name>M5G272_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624760.1">
        <property type="nucleotide sequence ID" value="XM_040773864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G272"/>
    <dbReference type="GeneID" id="63688926"/>
    <dbReference type="HOGENOM" id="CLU_2108935_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="115" mass="12883" checksum="81193A6473890809" modified="2013-05-29" version="1">MLVPSRYPKAFGRRYCVEDIRFSLCSYPFHGPDPFPNLGPFHGHELVGLGRSDPVLGPTSLHTCAYTQHPARAHARDLFPGLHPDRPVLQHLRHPSFSSPGFHQPALALSLELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2V5</accession>
    <name>M5G2V5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="10">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_20263</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10 13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10 13">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631455.1">
        <property type="nucleotide sequence ID" value="XM_040771866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2V5"/>
    <dbReference type="STRING" id="1858805.M5G2V5"/>
    <dbReference type="GeneID" id="63686928"/>
    <dbReference type="HOGENOM" id="CLU_023296_1_0_1"/>
    <dbReference type="OMA" id="HGTVQRH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000016">
        <property type="entry name" value="Isocitrate dehydrogenase [NADP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 14" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="18"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
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    <sequence length="419" mass="47399" checksum="454FD9A4F205D162" modified="2013-05-29" version="1">MRAHLRRYASTRIDVKNPVVELDGDEMTRIIWKKIREELILPFVNLDIKYYDLGIENRDATDDKVTVDSAEAILKYNVGIKCATITPDEARVKEFNLKQMWRSPNGTIRNILGGTVFREPIILDKIPKPIPGWTKPIVIGRHAFGDQYRATDFVAPGPGKLELIYTPTKGEKSVMEVYQFKGPGVALAMYNTDDSIIGFAHASFKMALAKKMVLFMCTKNTILKKYDGRFKDIFEEIYEREYKPAFEKLGIYYEHRLIDDMVAQAVKSSGGFVWACKNYDGDVQSDILAQGFGSLGMMTSELITPDGKTMESEAAHGTVTRHYREHQKGHETSTNPVASIFAWTRGLAHRGKLDDTPALIKFAQELETACVDAIDKDGIMTKDLALAIHGKNMKREDWVTTTVYMDHVRDKLKAKLDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G378</accession>
    <name>M5G378_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_21438</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772399.1"/>
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    <dbReference type="OMA" id="QMVIFAY"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF20">
        <property type="entry name" value="AAT FAMILY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
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        <location>
            <begin position="486"/>
            <end position="504"/>
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    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="47"/>
            <end position="509"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G417</accession>
    <name>M5G417_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_93378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631900.1">
        <property type="nucleotide sequence ID" value="XM_040777151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G417"/>
    <dbReference type="GeneID" id="63692213"/>
    <dbReference type="HOGENOM" id="CLU_1496156_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="19222" checksum="9D0D3A75B816961E" modified="2013-05-29" version="1">MPLFGHRRSTSPSNAAATPTPVNNAPVNDPAYNNTTTTGRTGSIFGRNRRNENVDDINGYNSGNDRYGNGVHLANQIGMASGDDMAEPRCSGSGSFFSRNSRNTSLDSQNIPVSLEHAHAKLDAAVASERAADSALRDARDMVDRIEREARREADVAAAKLKEARTMRKTAGGLGKFGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G462</accession>
    <name>M5G462_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinol-cytochrome C reductase hinge domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_80841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627519.1">
        <property type="nucleotide sequence ID" value="XM_040776478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G462"/>
    <dbReference type="STRING" id="1858805.M5G462"/>
    <dbReference type="GeneID" id="63691540"/>
    <dbReference type="HOGENOM" id="CLU_115913_1_1_1"/>
    <dbReference type="OMA" id="NEDCVEE"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="10">
        <location>
            <begin position="58"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="15280" checksum="2B22382723BDAD98" modified="2013-05-29" version="1">MTILSLLSSFVNTAYNEAQEAPEPAAAEEHKEEETAEAGGEVEEAAEEEEAEEEEPEDPMPAIREECANTKHCLPAKREFEHCEKKVNEGSARPHEDCVEEFTFPFCTCPIQTNIEYSLMHCVDNCSAPKLFSKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Y9</accession>
    <name>M5G4Y9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625715.1">
        <property type="nucleotide sequence ID" value="XM_040769107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Y9"/>
    <dbReference type="STRING" id="1858805.M5G4Y9"/>
    <dbReference type="GeneID" id="63684169"/>
    <dbReference type="HOGENOM" id="CLU_504343_0_0_1"/>
    <dbReference type="OrthoDB" id="2357318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="59092" checksum="440F7956058FBA19" modified="2013-05-29" version="1">MANDIRIQYAPLLALPRNQRLPSITATVCSLPQTRTRVEVLAFLYLQLRAHAREGSGRDASAVQALFLRECSAFLAQNEAAVSHIQFEAEDTHLLTPTIVSMSAALLQLQAHNLSLLPSLPSHLLLAISHSLNDPSALPLFTRLLATIPLSPSHAAPLLLLLSYISSLPSSPLLLLTSTSLSLSLLTSLLTHPHANSPALTSQILQHLSHFARVIWEEYAGVAGGFPQLLRVFYGCADVLSTSPPEAESCLRALIAQLKQAPTPSNASQEAYLFTLAETLLPILSPSLVYTNLLPLCIPALDNPAEKGAFEASHSLFLVILAMPKKGQAQMESTLNVQETVPYYISCLLKHLAETHLSPVQFRLAYTSLVQTCASLPPSLPSPSVSSLSNEGPTTTPEGKALAWFCVQQLLSALRDLTFLPKRELDYEYENEKVSALRETLVALVPVVPPSLLPHTLEGVEVYVLRPLRHPTHPTHAEQEQQEQEQKQERSPSDRQVLKTLFAVIRAVGEESRGEALGWFLGVVQRLGLGEEKEEVRARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B6</accession>
    <name>M5G5B6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_56662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625845.1">
        <property type="nucleotide sequence ID" value="XM_040775384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B6"/>
    <dbReference type="STRING" id="1858805.M5G5B6"/>
    <dbReference type="GeneID" id="63690446"/>
    <dbReference type="HOGENOM" id="CLU_015676_1_0_1"/>
    <dbReference type="OMA" id="EWCAFAL"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="616" mass="68173" checksum="2B9AEC4DE4FA23C1" modified="2013-05-29" version="1">MPARPLDYGTYVPPTSFPSFTKHGASLLPSTAAAPVSSSWLSSFASAIHARDIPCILDHLLPDAYWKDMLSLTWDFRAFQGQAAIRKFLEDRLALCEVRNVRLTDKLVPSVVKVGELSWVQASAEFDTKWGSASLVFRLVPYLPEPAEPAPNANGLPTEPDPEWCAFALFSNLDSLHGVIEQVGAHRVEHPPRKSWNALRAKELEFEQEGPTVLIIGGGHNGTMMAARLKYMGISCLIIEKEPRVGNQWRGRYSSLCTHDPVWFTQLPYLPFPSTWPTYTPADKLGDWLEAYASHLDLNVWLSSSLSSVTYSPEAKEWTAHIQRSEGTRELKAKHVVYAGGWNGVPYLPEVEGREEYEKAGGKVLHSSEYRDAKGFQGKKVVVIGAGVSAHDIAQDLINSGAGSVTLHQRSPTLVVSTRALRVLLNRSGFRQDGLPVDTADMLLHSFPMDIQKLTMAQSTKLLKDVDKDTLEGLDKKGFMLDDGPQGAGYLFLVLTRRGGYYFDVGASQLIIDGEISLKAGGEVSRLTPGVVHFTDNSTLPADVVVFATGFGAIKENLAQTFGEEFTAGLKDPWYLDEEGELRAVWRDSGQEGFWYMIGNLSYARFYSRRVALRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5F9</accession>
    <name>M5G5F9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630359.1">
        <property type="nucleotide sequence ID" value="XM_040772206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5F9"/>
    <dbReference type="STRING" id="1858805.M5G5F9"/>
    <dbReference type="GeneID" id="63687268"/>
    <dbReference type="HOGENOM" id="CLU_101432_0_0_1"/>
    <dbReference type="OrthoDB" id="444848at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="30643" checksum="A9B0230FE0227F26" modified="2013-05-29" version="1">MECQVKSSRTVERTSLLRLRSDSMERILDAALFATRVRQQTTAKWSPFELLYGRKPRLPFDQPLLRAPDAALPGDAEHSERYLQMQKAREEASERGTIRALADKERWDHQLNIGTEGTQQPFEVGQKVLLWNETANKGDAHWFGPFVITTKLDKGTYQLKDRRGHLRPGLVNGNRLRLAHLREDDTNHRAWVLPKATQRQWSKEDKEAASQAVVRAMPSIRIIGRFANPNTGSAPVTVTEDKTRSAPVTVAEDKAQSAPVTVAEDESQNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G683</accession>
    <name>M5G683_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_14748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630604.1">
        <property type="nucleotide sequence ID" value="XM_040771053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G683"/>
    <dbReference type="GeneID" id="63686115"/>
    <dbReference type="HOGENOM" id="CLU_055660_2_0_1"/>
    <dbReference type="OMA" id="CATAKTR"/>
    <dbReference type="OrthoDB" id="18440at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039258">
        <property type="entry name" value="ZNF511"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="37410" checksum="897C58A1C53A5FFB" modified="2013-05-29" version="1">MPKRPSSPSPSPPPKIRRSQRPEPSTSTGTGTSAALTCTLPPTCHRHPAVLEDAQALERHYRTYHTHVCQERKCLAVFPDDRLLELHFAECHDPIFAIRKERGEKTFACFIPTCPRTFLIPAKRRLHLIDAHHYPKEYFFAITNKGIGGLLQKWGEGVSLVRPEWKPRLPQMDGVEGQELAGIELEPPPTPITSTLSHGGAPNDTSLQQSKNGLGLSFLSADSNARESTMTNSGAGATGDSQPLGWSFPQPRSPPLQHTLKPSGPASSGRKPLIQKSVSDNTPSKMDSSMDDLTSVLSSVSLVPRTIRFGRGGAKAGFQRPPGWKKANAGTHDPGESTMPVDSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6V0</accession>
    <name>M5G6V0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_44769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632875.1">
        <property type="nucleotide sequence ID" value="XM_040774607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6V0"/>
    <dbReference type="GeneID" id="63689669"/>
    <dbReference type="HOGENOM" id="CLU_072640_0_0_1"/>
    <dbReference type="OMA" id="WEGGVYE"/>
    <dbReference type="OrthoDB" id="5175824at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="253" mass="29018" checksum="4733187EFB0B07FC" modified="2013-05-29" version="1">MASNTEDRLAALEARINLLEDHNAVRKLQHTYGYYLDKCLYNQVVDLFAEDCEVQFHGGVFKGKSGARRLYIERFQKAFVGGRNGPVFGFLLDHPVMQDIIDVSPDRKTAKARMRCLMMQAGTHDNAIDPNSANQPRLRQWWEGGIYENTYARGEDGKWRIKILNYRALWHATFEDGWAHTKPTFVPFLSKTVAQGDPLGPDELYEDKWLWPDTHTVPFHYPHPITGEWVTKEELHDPPKGDNGISAFADVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7P7</accession>
    <name>M5G7P7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_87031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776795.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G7P7"/>
    <dbReference type="GeneID" id="63691857"/>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OMA" id="GQINEMY"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140985" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="21"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="495" mass="54832" checksum="2D1D3BDD6B6773F2" modified="2013-05-29" version="1">MLILALWYFAALPLSNAVDPLVDLDYSQYRGIARGTGVTEWLGIRYATPPTGDLRWRAPQPPQHEDGVMEADRNPDDPTTSEDCLFLDVYAPSNATPSSKLPVYLFIQGGGFNENSNANYNGTGLIKASGMNIIVVNFNYRVGLFGFLSSTEVVANGTTNVGLLDQRMVMKWVQSYITRFGGDPSHVVIGGDSAGAAAVLYHLMAYGGRDEGLFHAAAAESSSFGNMFNVSQSQYQYDTIIERVGCGHDQVEDTLGCMRSLNASYLQKNNWNIPYPNLGSGASPPLYMYGPTIDGDFITDDSYRLLEQGKFVHVPVIFGCQMDQFLLDQFIMMTQEQLNKTNAMYRPAETYRNQGPLWRALSNAYGEMRYMCPGQAVGSAFSSAGTWIYRYNVMDPLEMEGGPYNVAPGSAPASYYPGQSNAAIIPIIQGYWTSFIRTYNPNIYRLAGSPEWVQWNAWAKDRLLFQTNATAMEIVDYGQQARCAYLQSIGVLTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Q6</accession>
    <name>M5G7Q6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633120.1">
        <property type="nucleotide sequence ID" value="XM_040769540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Q6"/>
    <dbReference type="GeneID" id="63684602"/>
    <dbReference type="HOGENOM" id="CLU_051060_0_0_1"/>
    <dbReference type="OMA" id="RTRIMPK"/>
    <dbReference type="OrthoDB" id="5374757at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40635">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40635:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="54041" checksum="E2F1672D47B3F757" modified="2013-05-29" version="1">MPYENRNAYYLRISPYTVLPMYLYLDERHTSWMTDTTLQFVLEDLRHRIGPKLRDESGTIMNASAANKTKPSVDVHRGTTYQFAYFLRKADPHTLLVKRRDFVLRPSAFGVKKEESQSPEPPPVRGKKRGKTKPTPKKSGSIETNGKGKKRKRGEQAALERDGPEPSEEDATLPPRRSGRTRAQVSYTEDEDEVDREDDEGEDNRGAQEAEEDDFELDEEDTADAAPEPLFRPSTPPRPPSEPEVKPEPADPSLNGSIPPTPTDNSVIDFSMDPDEEEENKPKPELQLSYQGFSIFGCALCVIVEPYPPIRYSVVPQPRARQTSLPVSWASSRSASMEPVGTGESRGTTPLFRAETPFDDQRFAAGTPAVDREETPLFRLETAEPEMRGHRFAAGRPDGDREQTPLFRFETPEPEMMRGASLAPSLRSPSPFVNGEDEPMDEDGSTIMEFSQVLSSAGAGRFGGRDDGDEGGEGFYGDADEGSGNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Q7</accession>
    <name>M5G7Q7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_116337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628814.1">
        <property type="nucleotide sequence ID" value="XM_040770184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Q7"/>
    <dbReference type="STRING" id="1858805.M5G7Q7"/>
    <dbReference type="GeneID" id="63685246"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_5_1"/>
    <dbReference type="OMA" id="CGAPIVY"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="52"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="477"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="572" mass="63633" checksum="40F22F795FC3DEDE" modified="2013-05-29" version="1">MSQPAANLAVPGFAPTAASIPPKDVNYRRPMAKNQPVWHTPLDPVNFLLRAALIYPKKVALAHLDVPYPVSYTYDVWAQRIQNLAYALIESGIKPGDRVAVIAPNCPMMADAHHAILAARGIITPLNYRLTKGEIQYILEHSGAKLILCDHEFTHLLPENHAPVIISQDTGRVGDPYEDFLARGRRFSQERGWSGLPIEPDENAGSCLCYTSGTTGRPKGVLTTYRGSYLAAVANAYETKMDLYSIYLWTLPMFHACGWTYPWAITFSFASQVTLRTVNYDLIWKNFKNSRISHYCAAPTVQIGIVNARHASYVEQPLRAIIAGAAPTAHLIGSLEKIGISVSHVYGLTETYGPFTISYDRPEYKTLTVDERSVFFARQGHSFATADEIRVIQHDNDSKDLVDIPKDGVVLGEITARGNVVMKEYFRDPKATAEAFKGGYFHSGDLAIWHPDGSIAVQDRSKDLIISGGENASSLAIEQVLSKFPPVLEATVVARPHEKWGERPMAFVILHSHEEGKWKGKDKEFEIELKKFARQSLPGFAVPEWVAIVKELPKTSTGKIQKNILRQRLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7R0</accession>
    <name>M5G7R0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UbiA prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_23390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626710.1">
        <property type="nucleotide sequence ID" value="XM_040773222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7R0"/>
    <dbReference type="STRING" id="1858805.M5G7R0"/>
    <dbReference type="GeneID" id="63688284"/>
    <dbReference type="HOGENOM" id="CLU_063928_0_1_1"/>
    <dbReference type="OMA" id="PFGKNAC"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26204" checksum="3E209943903E3536" modified="2013-05-29" version="1">MLWIWLHLLQCNVSNQYKTCDEDKINKPWRPLPANRVTFGQAQFLRWALVVVCALFSLSFGTDVAVVSLVLTLTMIVYDEVGLAGHWAGKNICAVYGYGTFEIGATKIMGETSDLDAKAQLSVVLSAMIVLTTIHVQDFPDIEGDAALGRRTIPIVFPGASRIVTPLLMLGWTAVVVNAWKLGLVPSTLMYTLGLVVAARIWADRSTSGDKTTYLTYNIWLICAHLLPANARFGVLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Y5</accession>
    <name>M5G7Y5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631139.1">
        <property type="nucleotide sequence ID" value="XM_040768073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Y5"/>
    <dbReference type="GeneID" id="63683135"/>
    <dbReference type="HOGENOM" id="CLU_2015194_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="13373" checksum="8D2E47C5F652050D" modified="2013-05-29" version="1">MLLNEVTVGKPHFEEEPAPGTQEAAELGEPKLAAVGEPLQMRLQKVLDHYCSHFTKGIPHAPTVSQEVEALLETGDATPQAENPRPMSQPQLDELQAQQPPQKGFYSTLNITMVITSIVCAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G828</accession>
    <name>M5G828_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_104813</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631813.1">
        <property type="nucleotide sequence ID" value="XM_040767983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G828"/>
    <dbReference type="STRING" id="1858805.M5G828"/>
    <dbReference type="GeneID" id="63683045"/>
    <dbReference type="HOGENOM" id="CLU_504341_0_0_1"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035098">
        <property type="term" value="C:ESC/E(Z) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046976">
        <property type="term" value="F:histone H3K27 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="411"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="61130" checksum="69EA93E49473EB10" modified="2013-05-29" version="1">MPDRRPAKELTEAILYPFYAEKRRYNATLYDIAVTHAIDQLRLYRQDAIKGVAAITKGHGETEEEIPSLQFQTGNNEQSYVWRLDKDTSPQAISHATIRLTGVDPAPQYETCPPASFNHLFAWDDGECVEFLPFPDDPTFNMEAYLEFSAEVDRYDIQPFSSDAGNGMAIYRKQLTFNYLNRNVADDQALRDTADAVFEQFDVTIELMEKIFTIFFALEINEYHSIMCTAVFYKDWLDLGKRINPNEISSLNELTGNFMQRHYCSIPSCRMPDCLHALAVRVTDQLPSVPKSARLGLRLAPAVPCGNACCYLEDKGEETEKLEEWDGLKIALLKAAVESYPDLTSAKFEMQRSQLEVEDSGPSPVTQRRAVRKTKQREISRQMADMGSQFESQTGYALGEQTCCSNIHLQEGFRPSVTVKPGKFGWGLFTDEPIKAHQHVGEYFGELMTVEREEREAGIGMFLGREYGYAANMEWSINSGNVGNESRFMNHSNKPNVWAKPINVNGDIRMGFIAASHIAKGAELFIDYGPLFFRNAAKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G848</accession>
    <name>M5G848_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome activator pa28 REG alpha/beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_54841</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PA28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626830.1">
        <property type="nucleotide sequence ID" value="XM_040775288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G848"/>
    <dbReference type="STRING" id="1858805.M5G848"/>
    <dbReference type="GeneID" id="63690350"/>
    <dbReference type="HOGENOM" id="CLU_062515_1_0_1"/>
    <dbReference type="OMA" id="EMDQINI"/>
    <dbReference type="OrthoDB" id="6591885at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008537">
        <property type="term" value="C:proteasome activator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000045">
        <property type="term" value="P:regulation of G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.180:FF:000002">
        <property type="entry name" value="Proteasome activator complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.180">
        <property type="entry name" value="Proteasome activator pa28, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003186">
        <property type="entry name" value="PA28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036997">
        <property type="entry name" value="PA28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009077">
        <property type="entry name" value="Proteasome_activ_PA28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036252">
        <property type="entry name" value="Proteasome_activ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660:SF2">
        <property type="entry name" value="LD45860P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660">
        <property type="entry name" value="PROTEASOME REGULATOR PA28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02252">
        <property type="entry name" value="PA28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47216">
        <property type="entry name" value="Proteasome activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome activator PA28 C-terminal" evidence="4">
        <location>
            <begin position="73"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="218" mass="24739" checksum="998C122B5E9FC387" modified="2013-05-29" version="1" fragment="single">DLQDLVTTIASKPSHPLHVSQFSRSSIITTASLPSTDASTSAPHTHSKKRKLDNGAEAHGEVHEQEVKYIEYVPGNGQVTKEMEAIRSEFEELISLVDKVKLWVNMMMPKVEDGDNFGVEVQEQVLGELHRAQEAGYNLLDGLKTYHMNRAKICSKLIKYPNLPDYAEALRRHDEKAFFGIRQNLVDLRSIYCVLMDLLHKNIQKIRAPKGNNREALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8A1</accession>
    <name>M5G8A1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription initiation factor TFIID subunit 1 histone acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_117598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626880.1">
        <property type="nucleotide sequence ID" value="XM_040770416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8A1"/>
    <dbReference type="STRING" id="1858805.M5G8A1"/>
    <dbReference type="GeneID" id="63685478"/>
    <dbReference type="HOGENOM" id="CLU_000572_0_0_1"/>
    <dbReference type="OrthoDB" id="5752at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041670">
        <property type="entry name" value="Znf-CCHC_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15288">
        <property type="entry name" value="zf-CCHC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 1 histone acetyltransferase" evidence="6">
        <location>
            <begin position="342"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc knuckle" evidence="7">
        <location>
            <begin position="1001"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="808"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="844"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="686"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1088"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1098" mass="123688" checksum="1C1E6D4549E343E7" modified="2013-05-29" version="1">MAEDRDEASFFSSLAGFSLGSVLSEMEVNTSGLSNQLGLQGMGFDLGKGIADEEPTGRDTGDDWEEEVDREMREEGANGMVATPVGGPRSIDMKPLMPLEHMEVISKKQVEPERSVYDLFPSFRPDKVLPFTEIFASKPVRKRHYPTRTATIELVTGPPSPPPGPETGNASKPGPGQRNLLSEDLFDIIQPVLPRKRAEWETEGSIDDTLRRAILKRRKLGEELFDLDMVEDVFDPVMIAPWEKDIMWKPPNKAHVKHTDQDDSQPHYPEYNAWLDSDDWAKSIMWTPSTLFKPFLAPPKPVAVAEKHEQPTAPIPQPLSRKARLQQSIISNRAAQQVKDKFNLSNDHMYETLHGRGVQRGVRQTFGNLEVQHAYPAQKLQLPFFKTRLGKSEARAWHRPALLFPTDMELRFSRVRKRDKDKSKRNKGEGQEMRRTSDLTLKDGSNYLLWEFSEEFPPIMSSIGMGAILVNYYRKRTEGDDHVPKADVGVAFVLEPKDESPFLKFGSAEPGQMVPTLYNNLIRAPLFRHKPYATDFLVVRSTQNGETKYFLREIKNLFVVGQTYPVVPVPGPHSRAITTTIKKRLEGIVYRLLKKSKQERIKISRLMKYFPDQNELQMRGRLKELMEYNRRGEHQGYWRLKSKHTLLPDSEIIALVTPESVVLCEAMQVGQRHLLDAGYGQAADGAGEEAEAGEGEDGEGMGIEQQLAPWIATKNFINATQNKAMLKLHGEGDPTGRGEAFSFVRVSMKEIFIRAGEDAQEKIAEANARPKNAHRYNVQQQQQIYRSEIERIWKAQYDSLSSKIEPDLDVEEEEPMRGSRQPSVGYSAPKPITFRDERQFPTAHTAFSPPVRSPLAAGPSYVRGASEYSRGSSADLERDMEDDMLSQGGVAANQASANRVLRIRRMQPDGSWKTEIVRDENVINVYIRARRNIEEENMMPDVALPTGDATTDTRMRKRLEAEISRMKRNQERRLTRKNQSLVKSGGRPIQLDRPAKADTSRRCGNCGQIGHMKTNRKCPRYAEFNPVPTTATPIAASPPAAHAAFPSFSTPGLARQASAFGFPNVSSPLATSPPLVRDHAESPGARPPKLKITIKNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8E7</accession>
    <name>M5G8E7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20963</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631324.1">
        <property type="nucleotide sequence ID" value="XM_040772167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8E7"/>
    <dbReference type="STRING" id="1858805.M5G8E7"/>
    <dbReference type="GeneID" id="63687229"/>
    <dbReference type="HOGENOM" id="CLU_000288_25_2_1"/>
    <dbReference type="OMA" id="ECICNIV"/>
    <dbReference type="OrthoDB" id="5337378at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="32975" checksum="E062B4BC4D4CF182" modified="2013-05-29" version="1">MARHPAPGEEGKVWCVKRRKNPFEGAKDRQRQLEEANILQYLATPSVGGPHSHIVQMIDFWEEQNTLYIRTELCGLGDLSILLQEFGRISEDGLGEARVWKILNQITKGLLHVHQAGILHLDLKPANIFITDSGVLKIGDFGLATRWPRPNAALERGFEREGDREYMAPEILRGVYGKPADIFSLGVLALECICNIVVPDMGEPWHKLRTDDFSDTELSGIASFELSSLIIGMMHSDRTLRPSIQQIRASIAFQRLEGMLASGVVGSAIEPEEPAFLASLLGYSGPEPVEDSMDVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F6</accession>
    <name>M5G8F6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631933.1">
        <property type="nucleotide sequence ID" value="XM_040768000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F6"/>
    <dbReference type="STRING" id="1858805.M5G8F6"/>
    <dbReference type="GeneID" id="63683062"/>
    <dbReference type="HOGENOM" id="CLU_1057764_0_0_1"/>
    <dbReference type="OMA" id="VARIPWI"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF7">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="32"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="28375" checksum="755CE27F9EB0F223" modified="2013-05-29" version="1">MPIDLSDASKAALEHIVQSLELTTNMRVLIVGAGGRLGLRVVDHLLTASNEVIAFVRSPSRFLSLLPEPLRTSPSLQVIEGDALSPSSLLSAIRDSNPDAVISSAGVPAFFPWQHSTFPGIGKAVAEACKEALGGGKRVWFVAGMFVCDRPGGGLLMDSTHIYTETRIVLTHLQTKCTDLNWAIVCPSLMYHGSPKPVEAAVNIPPHWPIPGWACRLPLIGFVLVSFATALGYALSYDSVAAWLVQDLEEERWRGKRVALKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G958</accession>
    <name>M5G958_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631609.1">
        <property type="nucleotide sequence ID" value="XM_040771906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G958"/>
    <dbReference type="STRING" id="1858805.M5G958"/>
    <dbReference type="GeneID" id="63686968"/>
    <dbReference type="HOGENOM" id="CLU_089717_0_0_1"/>
    <dbReference type="OMA" id="KIYANMS"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="182" mass="20371" checksum="D3D8E764447009E9" modified="2013-05-29" version="1">MSEASTENKLRIAQGKKDDGNAAFKSGQYKDALRFYYEAILYVQGLEKSLSSAMDSNISGGSGSGADEKRRPKTEADVLLVALYNNMAAVHLKLANWKRAFESAEKALSRDEENSKAGFRKSQALVQMGERVKAIKLLEELAKTHPNDVDITRELSTQKQNEEKSEREHDKVFKEAWKGKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9I1</accession>
    <name>M5G9I1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_115584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629416.1">
        <property type="nucleotide sequence ID" value="XM_040770036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9I1"/>
    <dbReference type="STRING" id="1858805.M5G9I1"/>
    <dbReference type="GeneID" id="63685098"/>
    <dbReference type="HOGENOM" id="CLU_894350_0_0_1"/>
    <dbReference type="OMA" id="ANIACHY"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF32">
        <property type="entry name" value="ARGININE METABOLISM REGULATION PROTEIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="33364" checksum="E1DAAEEB6A0FEDC3" modified="2013-05-29" version="1">MAPKRKAAVVAAAAPVDPSLREGDAEETSPPGAPEAVEAHPPPAPLPYPLPHVTDDEKIAPTTEQAIPTNLLQPPAGYYGIPYPPWGFAPIPYPPGAPGAPFPPPGYQLPPYYANGQLPPMPGLIYGPAPVPVPPPKADSAPSGEGDEGYSEADENPKPEDDEDYKPGKKHQRKSKAALPHDPDHAPKKANIACHYCRKRKIKCDETRPSCLSCVRLGQDCFYDDLRRFRGKAKSTLAKEKKSARMSARHKANSFAKEMPQMKFSALPMPGDPSLTEALSLAAMGPMPPGNMPKFMFWNAPPAANVDASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9N3</accession>
    <name>M5G9N3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial inner membrane protease subunit</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_117025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627425.1">
        <property type="nucleotide sequence ID" value="XM_040770303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9N3"/>
    <dbReference type="STRING" id="1858805.M5G9N3"/>
    <dbReference type="GeneID" id="63685365"/>
    <dbReference type="HOGENOM" id="CLU_028723_4_3_1"/>
    <dbReference type="OMA" id="YFGPFWN"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="9">
        <location>
            <begin position="26"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="193" mass="21465" checksum="B4248FAA64247508" modified="2013-05-29" version="1">MATRWALNSLRYFVPSPPPRGKLLYYTKRTLQLCGLVWCIEHWFFDLRLCVGASMLPTMRCEPTLALALMYPSLLRPPSLKLGDLVVARSPTHPRKEVCKRVIGLPGDTVCVDPIGAVRGHGGWEDAKGGKEHVVVPRGHVWLAGDNMSASVDSRMFGPVSLGLVRGKIVFRIWPNWGPLGNTFHELDIDPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Y1</accession>
    <name>M5G9Y1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627550.1">
        <property type="nucleotide sequence ID" value="XM_040771212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Y1"/>
    <dbReference type="STRING" id="1858805.M5G9Y1"/>
    <dbReference type="GeneID" id="63686274"/>
    <dbReference type="HOGENOM" id="CLU_2209929_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11919" checksum="D12A65A00EA18C63" modified="2013-05-29" version="1">MSSLLALQEGFIIISVANRKWEECVAMHAIAVSRTTKIASFHVGGQTLHSWARIGGHCENLEEMCGEIQRDPKKRQCWLDVKVLLIDGISMLSASLFDKLAQTAQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAH4</accession>
    <name>M5GAH4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein N-terminal glutamine amidohydrolase</fullName>
            <ecNumber evidence="3 8">3.5.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Protein NH2-terminal glutamine deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_74557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50680"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="Rhea" id="RHEA-COMP:12777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="EC" id="3.5.1.122"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NTAQ1 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.122" evidence="3 8"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632249.1">
        <property type="nucleotide sequence ID" value="XM_040776073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAH4"/>
    <dbReference type="GeneID" id="63691135"/>
    <dbReference type="HOGENOM" id="CLU_091083_0_0_1"/>
    <dbReference type="OMA" id="YIADAIQ"/>
    <dbReference type="OrthoDB" id="191192at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008418">
        <property type="term" value="F:protein-N-terminal asparagine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070773">
        <property type="term" value="F:protein-N-terminal glutamine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.10">
        <property type="entry name" value="Protein N-terminal glutamine amidohydrolase, alpha beta roll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037132">
        <property type="entry name" value="N_Gln_amidohydro_ab_roll_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039733">
        <property type="entry name" value="NTAQ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023128">
        <property type="entry name" value="Prot_N_Gln_amidohydro_ab_roll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035:SF0">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09764">
        <property type="entry name" value="Nt_Gln_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein N-terminal glutamine amidohydrolase alpha beta roll" evidence="9">
        <location>
            <begin position="12"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="227" mass="26422" checksum="434091BC6BDBC058" modified="2013-05-29" version="1">MIPPCIPTQLTYTPNFCEENVYCLARYFTRPGLERLQNTWSIYVVFISNEDLCITLLQQKGSKPQEGGLIVWDYHCILVLVAKPSESSENQAGSWVYDVNSLLDIPVQWYTYVTETFPFRETVPSRYRCKFRVVDAQDFLAWFASDRSHMLIWDDKLHANRYVSKPPEHLPIIGSAARVAGITNNLMDRFVLMQPVEVQEEQYGRVMDQDTFCSLRCISPIFFINQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAK6</accession>
    <name>M5GAK6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="12">2.4.1.132</ecNumber>
            <ecNumber evidence="12">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_75319</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10 12">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="12"/>
    <dbReference type="EC" id="2.4.1.257" evidence="12"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632783.1">
        <property type="nucleotide sequence ID" value="XM_040776127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAK6"/>
    <dbReference type="STRING" id="1858805.M5GAK6"/>
    <dbReference type="GeneID" id="63691189"/>
    <dbReference type="HOGENOM" id="CLU_030619_0_0_1"/>
    <dbReference type="OMA" id="AMYMKCP"/>
    <dbReference type="OrthoDB" id="448893at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004378">
        <property type="term" value="F:GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102704">
        <property type="term" value="F:GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="14">
        <location>
            <begin position="24"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="370"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="525" mass="58346" checksum="7AF452B634666080" modified="2013-05-29" version="1">MAKKAKSQRLSSLRIAIIHPDLGIGGAERLIVDSALGLQRKGHEVEIFTSHHDPKHCFEETANGSLKVTVVNPGIPASLLGHFRIIFAILRQLYIYFYLYLLITLPHSVLRIFGLQQIPSPDVFLIDQLSTVTPLVRWFLLRRVVFYCHFPDKLLSGGKAANADGEILKEGIVKRIYRMPINVLEEITTGNADLVIANSLFTARVFKKAFPMLSKTPRVIYPGINLAAYQQDALEDTDDARSIRKITADVPFILSTNRFEEKKNIALAVEAFAQYRATHRPTRNTPLLRLVLAGGYDPRLEDNVRTLAHLRTLCDESKLSYAIVSPQTFDLPTPAPSVDPSGTDVIFLLNFTTAQRTTLLLSPQNLLQLYTPTNEHFGIGPVEAMACGVPVLATNTGGPIESIVDEPEAERTGWLCPADPEKWAEAIDQVVRLSAPDKAALAERAKERVRINFTQEIMCEQLDLALWSIWEQGSMDHRMRDALCTMPIAAAAGMVSLRFGLAEDVSWIVTLATFVAVAVYLSNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAM8</accession>
    <name>M5GAM8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_22814</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627870.1">
        <property type="nucleotide sequence ID" value="XM_040772961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAM8"/>
    <dbReference type="STRING" id="1858805.M5GAM8"/>
    <dbReference type="GeneID" id="63688023"/>
    <dbReference type="HOGENOM" id="CLU_1302288_0_0_1"/>
    <dbReference type="OrthoDB" id="21557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="96"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="22505" checksum="0B3F11E809EE1877" modified="2013-05-29" version="1" fragment="single">MMDTALLAHKECRKRQAKEQACSSLEPLQDTPPTGAAPASASSSQTMTDDAAVSQTNGSAVGIQKQDATLLDCLNCKRPIAFNRYAPHLASCMGLNVGSRRGQPRNASKRVDSEGTRSASPQVFSEEREATPSGPKTTKRNRSPSEMSLRDTKRPKTESRRTTPQPKSNGIAALLPGHYANSVPKAPSKLRSSPVASQGISGSPVASLDNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBA4</accession>
    <name>M5GBA4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632564.1">
        <property type="nucleotide sequence ID" value="XM_040767883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBA4"/>
    <dbReference type="GeneID" id="63682945"/>
    <dbReference type="HOGENOM" id="CLU_663962_0_0_1"/>
    <dbReference type="OMA" id="MPVERTR"/>
    <dbReference type="OrthoDB" id="3244253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="414" mass="43063" checksum="7125911836AAFF96" modified="2013-05-29" version="1">MSNSDSATLGGTETFSSASQLPTDLLTNPEASEGSAPSLPTGASVVTVTYQVGPTSTPASTSQGNGIPIGAIVGGALGGMAIVALIVFGWIWWGRSLKHQEMEKKRLAEENAMKKPRRPSMKHISSSTGSSFLTRDGKTVSFEIVHPNTAPSKPPMQTRRPPAGPNAAATGTTAAAGAVIGKIIVTPPEDAEHPRVRSPDKPEKSPFRPSRRHEAALAATHARTGSGGSYRPSPLSQGESYTAEKKEERGGRPPGAAPAVYGPPVPMPVERTRTTSSRSASASTTPTQTASGSRKTPSPSSPPPTPPFLRKSPSKGRTNASLAALHAAATTPTPNLSLLTQADGRVNRLSAVSVQPQPKEWEADQHPMPVSPGAHGRGYGQGQGQQGQGLQVPNAEEQMIWRGSRVESSSGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBY8</accession>
    <name>M5GBY8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_112789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632869.1">
        <property type="nucleotide sequence ID" value="XM_040769514.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GBY8"/>
    <dbReference type="GeneID" id="63684576"/>
    <dbReference type="HOGENOM" id="CLU_002295_0_0_1"/>
    <dbReference type="OMA" id="KKLPMND"/>
    <dbReference type="OrthoDB" id="15425at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="5">
        <location>
            <begin position="819"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="427"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1250"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1405"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="575"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="612"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="678"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1412"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1469"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1512"/>
            <end position="1559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1646" mass="177234" checksum="B86F89EFDFBB3C5F" modified="2013-05-29" version="1">MAATQTRRPGASHSPIDPGQSSPSPSDYASTHTVLSPEPDTSDIDESALVDGSVDEEEELYSDRSSSLEIPNESIDFDVVYSLRHFVATIEGQASVSKGDAMCLMDDSNSYWWLVKVLRSEDIGYIPAENIETPIERLARLNKHRNVDLAAATQAERDAHPALSALAARRARDLQSSSANSSRRGTPPNIPNTNRANSSNSKARVIFSTNFVIHNYPPAVWDTPLGEEHDSGSEEGDWEQEGMEVEDSTGELEPEGARDQEMEVDTEGMDAHANGVGLTSWEDELEPDDGIPWSGEALAGAAAGQQVQGQGHQHHPAIRGPTPPGTAHHLNNSNVNNSPSGNSTPSPQQQKAARQAQLGNGLASTLRAQSGTSQQEPEQKTQVQAPAQPRERLLSDPSPAPSVYSLSAESGVVDPAYALGQQILAGASQARQEQTQPQVTPLRPARQSTPGLGISAPAAGGQAASSSQPARPSQIMQAAQERAVQRQLSASAPPSTVAGSGSGSDRERERETRQRQGSTVSLTRTGSDGSGSASLASRGSGLVTSPALSESEIVGPAGSKRARQAEQGPRKLRKQTSEDFKDPQREKEKVEKVEKDDGKKKGGLLSGLFGRKNKESKEKEKLERERVEREERERQRLQIEQRDRDRQGQGQGQQRQGEHAREASEESQASFVSPPPASLLQQAAQPQQGAKRSNSVNRTGQEASPGTPSLVSLSSAATSPAPSTQASSRVQQLDKEQQDRYAQYLAATVKSSSMPAGGTGFATQSAAAMAQNGAATRLQHAQALAASGSPGPQKPSRPGSLILMNGILPPDGVPPELSVLRVFAGEDIANLTEATFKTVLLGPNTSSRDLIRQAVQRFHLPEDDTDPSPLDHPGAEGELHGEYYLTVKQADGGQEAVLMPDEKPLAVFEELSAAGAPLPPSVSKRASFGSINSMVSNLSAMTAIARLPMSDFTDDSRVKFYLQRRKRITEQDGVPTLSGKGLTMDSSMVRDESGIISTSSSGLMSEDLMQNNSLETSFSFSSNSTVGPRRLSSDRFSASSARFALQTVIHPSDLPDGMVFDPHTEAIVPRSALLNRSGTASASASPGISQTQRKKVFIFARNATVAEVIETSLDRFGIAEGVVDGGDDVEDRMVKRRSVTRVRYGLSVEIDGEERLLHPSSKIIDAFPRQPAFRVQDFRRTSESKRRSIDEPSVLGTLEDIQADDPIFVLRRAPGNSAMRNSGSSRHSRHSVPLDDVALAKLHAERRASASMLSMSSDRGSNVTDPDSAALSRQEIIREQRAQSRARQHGLLSAQTSDQGTNLVLPDRSQLRSTKSSSSSKVRYSYIHPDGEMYDISDIIEDELGTSENDTIRLSAAMDVGSLSGTEDLLEEVLATASQGRDARSGVEQRLERVLNRVQEKRQSASLALPNLGQTHRSSGASAGSFYSDDPRRSPRLDTSFVDIEDPHQRSQSQRYQAPASPPSPTIPSSPISGRTSTPSPKPAGPRHPHPTHSRQQPSIASVLSDLSMYDGGSSTPGSPRSPASMPSPSMPLTTTPTTMTSSSQTSSSTAATSAGVHAASRKPLVIKSDFAGLSRMMALIQLRGDMERPPKRKEEPEVDRMMFGPRMDLETLHPSVRDLFEPHFKQMEEYDQRLDRLLMSTVRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC82</accession>
    <name>M5GC82_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
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            <strain evidence="3 4">DJM-731 SS1</strain>
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    </evidence>
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        <source>
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    </evidence>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
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                <person name="Benoit I."/>
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                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
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                <person name="Hori C."/>
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                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
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                <person name="Martinez A.T."/>
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                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
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                <person name="Kallen N."/>
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                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
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                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
                <person name="Sun H."/>
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                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Ferreira P."/>
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                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
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                <person name="Hori C."/>
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                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
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                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629170.1">
        <property type="nucleotide sequence ID" value="XM_040770114.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GDD0"/>
    <dbReference type="GeneID" id="63685176"/>
    <dbReference type="HOGENOM" id="CLU_002668_1_0_1"/>
    <dbReference type="OMA" id="RQTKTRF"/>
    <dbReference type="OrthoDB" id="27683at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003980">
        <property type="term" value="F:UDP-glucose:glycoprotein glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06432">
        <property type="entry name" value="GT8_HUGT1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000065">
        <property type="entry name" value="UDP-glucose:glycoprotein glucosyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040497">
        <property type="entry name" value="Glyco_transf_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040694">
        <property type="entry name" value="UGGT_TRXL_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040692">
        <property type="entry name" value="UGGT_TRXL_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040525">
        <property type="entry name" value="UGGT_TRXL_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18404">
        <property type="entry name" value="Glyco_transf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18401">
        <property type="entry name" value="Thioredoxin_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18402">
        <property type="entry name" value="Thioredoxin_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18403">
        <property type="entry name" value="Thioredoxin_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06427">
        <property type="entry name" value="UDP-g_GGTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067680" description="Glycosyltransferase family 24 protein" evidence="10">
        <location>
            <begin position="22"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="11">
        <location>
            <begin position="37"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="12">
        <location>
            <begin position="295"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="13">
        <location>
            <begin position="424"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like" evidence="14">
        <location>
            <begin position="708"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosyltransferase 24 catalytic" evidence="15">
        <location>
            <begin position="1241"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1544"/>
            <end position="1579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU02273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1579" mass="176805" checksum="78684FC586E97FE9" modified="2013-05-29" version="1">MLGRTLARLSPLLLLSQAVGALESPPVQVSLRTSWPAPPLLLELIETAAQAKPDRFFEIAALLSHLGPLDDHSPEQKYTSAIRELKVNQILERDVDTKMFELEMAMHRMNPLIMAHFQADAGAQPVAGCESWIEWGEERICDMEKLREFVRKQEWPSAPQVFPFDHIHEHDEIVPHATILHHANPHTTFFASAHMYLSSIPHIRYVLRWTPPVAPASDPAYLSGWGVALDLKKTEYSALDDRLGKSSGSDSSKPREESDELRLIHHLIEEYLGTDNKREESKSEENNDGRKDFTTPLTEEEQLALPLQITQLILSAEDKLGALASISQSFPTLAPIIARSMPPPDPLSYEPQLTPGFSAIWLNGASLSPNDFSELGLPRKLRKETSLINSIARLGLTDVQATVVLANASMPGQTGEDSVTEGRIDIREAEDEQDAIVWWNNVAKDQRYKKYGSSLLGLLRPVYPGSFHPVARNIYNALLYVDYANSESVQVIAGYVGPLIQRNVPIRFATVPAGDGDSKKFAHVINYLIKTYGRAAAMKFFTALATDPVATREGNIPLTAIRRVYNSWMTSAQLPHIEGTEIKPWEIIVESPDEIAEAAERWAKRLGIYGESGGFVNGKWIPFDDTFLIKMQTETSRCLQHLQEQLYYGRMNDLEDIETYFYRLPGSIKRVSRYVHPSTDRPLKFMDLSEVFLQAGWNSRWIWPTGHEDVPVSIWVVADFSTAVGSHLLRETLDALQSDSRFRLSFIPSTAAHQFPDAAEAMSLTELLYRLTLTNKLSSVTPEELQNLIAHGSHPELHEMMDDSQRLLLQQAIENADEFKAWLTKGASVAKLFGLSDDRSGIIVNGRIIPVSGEDLAAADVQAIVGFELLKRVSPVITGMEKLWTAAGSPFDRRSYADIVAYVSSITSSVQAPDPSAGMLQTTVPQRSVLYKDITKGYSYFTIGDETSAIHRFGVILDPLTEQAQRWSGLLKWLQSLDTVYVEIILNPRADGSAAPLKSYYKSVLPFQLAFDDNGQEKKPVARFDGLPENSLYTLSMDTPSAWLVRPRESPYDLDNILLGTLPQTARNEGVAAIFELQFLVVEGHARETHSRSDTPPRGAQVQIADINSSIALDDTMIMANLGYLQLKAQPGVFEFGLRPGRTSEVYELEAVGNDGWGGKSINETGPYLTMTSFEGMTIYPRLNRKAGMEKAEVLEEVASPGLGLDLGGILDPLYKFASKLGVNLKPESTDVTTTKPQADINIFTVASGLLYERFALIMTLSVMRHTNHTVKFWFIENFLSPSFLEIIPNVAQEYGFDYELITYKWPSWLRAQKEKQRVIWAYKILFLDVLFPLDLKKVIFVDADQIVRTDLKQLIDVDLHGAPYGYTPMGNDREDMEGFRFWKKGYWKEQLRGKPYHISALYVIDLVRFRQLAAGDRLRGLYQGLSADPNSLANLDQDLPNNLQHEIPIYSLDKDWLWCETWCSADRFNKAKTIDLCQNPLTKEPKLVRARAIPEWEVYDSEIAALTRRLAKDGKIHWSAAMADSDALAEVGKANAAAVGVAEDAEETNEHTSEALPEASVVPEEMGAGQSHRIKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDD7</accession>
    <name>M5GDD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631346.1">
        <property type="nucleotide sequence ID" value="XM_040772176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDD7"/>
    <dbReference type="GeneID" id="63687238"/>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OMA" id="MSANGEF"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="293" mass="31538" checksum="8DF03B8634E9D551" modified="2013-05-29" version="1">MAAGNYALDANPSNSQIDIETNGSDWLWAVCATFLFFDLLFVLWSFTRPRGSRAFHILAIAILSVGTIAYYSMASDLGATPVIAEFYGDRHQNYAGEPATRAIWYVRYILWFINAPLLVLAIALASALPVSDIFGAMFMIDVTVICGLVGALTPSTYKWGYYGFGVGALIYTVSVLLGPGRISAGYVGSDIASIHTRGVAYLSFIALIYPICWGLSEGGNVITSDGEMVFYGILDLFTMPFFLALHMFQLRAVDLGRFGMTGVGIGGVGRSYVRGEKDAPLVPAQGVPEVGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDV0</accession>
    <name>M5GDV0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH3-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_115714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629597.1">
        <property type="nucleotide sequence ID" value="XM_040770062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDV0"/>
    <dbReference type="STRING" id="1858805.M5GDV0"/>
    <dbReference type="GeneID" id="63685124"/>
    <dbReference type="HOGENOM" id="CLU_064552_0_0_1"/>
    <dbReference type="OMA" id="EWWKGRN"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="81"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="27763" checksum="A22E97284BB2D72B" modified="2013-05-29" version="1">MAAPYIEHIVSRIKADLDFLESQSLITRADKDAALARLPTADVRSVDSKLSNLTLSSATNNNPGQRTMPARPGSVMPPPPPPRAQAKANWAYNSGDPQDLVFQEGDVIDIVEETNGDWWKGRLNGREGLLPANYMTKLPPAPVRSPNPPAYTPDRTVYAPPPSEPKQYYPPTGNPPWAQQPPQPSWQQPPQPTWQQPPPQPSWQQQPPPPQPQPVQQDPPKQSRFGGLGQVMATSAAGGLGFGAGAAIGGDLVNAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF99</accession>
    <name>M5GF99_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_112861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632976.1">
        <property type="nucleotide sequence ID" value="XM_040769523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF99"/>
    <dbReference type="STRING" id="1858805.M5GF99"/>
    <dbReference type="GeneID" id="63684585"/>
    <dbReference type="HOGENOM" id="CLU_115063_2_0_1"/>
    <dbReference type="OMA" id="LNAWSCV"/>
    <dbReference type="OrthoDB" id="67317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056552">
        <property type="entry name" value="Ribonucl_Kappa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23489">
        <property type="entry name" value="V-ATPase_su_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="9623" checksum="52DCBA5B319EAF71" modified="2013-05-29" version="1">MSFLTQPMFSIPSAGMCTVVSLFGTIVLAVFAFMFDNNYEAVMGSKKDPEDGHAVARTLYISALVYACLVVFCGCQTGLGARRSRGAISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFH1</accession>
    <name>M5GFH1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631027.1">
        <property type="nucleotide sequence ID" value="XM_040769840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFH1"/>
    <dbReference type="GeneID" id="63684902"/>
    <dbReference type="HOGENOM" id="CLU_2512587_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9176" checksum="949C67FB9FC7C7D2" modified="2013-05-29" version="1">MSPLGGVARAPPVVPGQPKPQPRSSHCLTPQLALFALYSNKNDSRSDSSHVMPFHTSLGWCIHLALIGSYRISPDHTNKATSSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFN7</accession>
    <name>M5GFN7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Splicing factor u2af-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_76651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HTATSF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631167.1">
        <property type="nucleotide sequence ID" value="XM_040776217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFN7"/>
    <dbReference type="STRING" id="1858805.M5GFN7"/>
    <dbReference type="GeneID" id="63691279"/>
    <dbReference type="HOGENOM" id="CLU_026945_0_2_1"/>
    <dbReference type="OMA" id="DTDFRFG"/>
    <dbReference type="OrthoDB" id="10258585at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000105">
        <property type="entry name" value="HIV Tat-specific factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034393">
        <property type="entry name" value="TatSF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608:SF0">
        <property type="entry name" value="HIV TAT-SPECIFIC FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608">
        <property type="entry name" value="SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="133"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="399" mass="45279" checksum="E9312A2076D6D907" modified="2013-05-29" version="1">MSPHPSAAASNRSSARPADPTQLGEPGFVQDPRVYMDRVTGTWRFEDDDEEGTEMEWDAKKRNWVPVIDEDLVRAQQAAYSVQGVDESAPAAPVLAREKKKRKKEQVDYTSGNTTPLPPAKKTKPEPKRGKNTAVYVSSIPLDATKDEIIDRFGKFGVLEEEDEGEPKVKMYADEEGLFNGTALVVYFKEESVTLAITMLDEAELRIGEGGSMRVELPNYDNDKWKNKREAKVERKVVDKSKASRRLKRMEGRIAEWDDEDGFGPQLEKKEPLPAPLESRVVVLKHMFTLDQLASDPSLLLDLKEDVREECEALGQVTNVILYDKEPEGVMTVKFRDPVSAQACVLKMNGRYFDKRRVLAELYTGRQRFKRTGDDITKEVDEAEKQRLDEFAAWLMAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG46</accession>
    <name>M5GG46_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_114176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631747.1">
        <property type="nucleotide sequence ID" value="XM_040769771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG46"/>
    <dbReference type="STRING" id="1858805.M5GG46"/>
    <dbReference type="GeneID" id="63684833"/>
    <dbReference type="HOGENOM" id="CLU_302678_0_0_1"/>
    <dbReference type="OMA" id="CQLRIRL"/>
    <dbReference type="OrthoDB" id="4064873at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="985" mass="111461" checksum="D8EA67CBF072CCF1" modified="2013-05-29" version="1">MDALPGSMATSPLISPFDTNPSAFPFLPVAAHHIHQSPDEQLPLINGGSSPKNNKRKRTRNEEDRPEPRRLKRTYESCARCRSKKIKCDNNSPRCKNCADANVDCQQEDRQNKTLKLRGHEELLQSQLNCCVLLLKHRDPYFDLSRLEQFISDDKIQISEEDADVLRKNSQLLRGINPSPRSRPIKDLPQRPTQGDISPNESEETYAPTYPPPPPPPPLTIPPTFIPPTFPFSDRTEFAGTKLAPTFEFDGLPPELVHGNPGDDLRGQDPRGNDLSNSAAAARSLRVDRILRESSFLIPHKARMMNDEDSPDLPDRGRTPYEGPEVPTDDPALMGDIEENQWLSRPVIRNEHPGKPPTDKEKNRVFLPKNRTEVARLVDVYFQRLNHLRPVFSSRAWFDYKLQEEYRLIDRWNAFGTLADETEKPRPPPPPEIIRRRKKGKKDEKDDDPGFLCSLYLILAISRMADIASDRQEAKRSDMKHFPVPAHFFKRAVQIKAELRVTISSLQALILMQWYLYTERHGRTLWRLVGNLVRLAIELGLHHDPIDSGDTFDPDEIEDRRRLWWIVLVQDRGTSVLLGRPIGIGENDYNTHKPESETNFDIGLEITHIQAQICDTLYRPGKISGEELFKFANGINTKLVQMRDALPPEYHFYTKDTENWGDQQKMVLLANLSQEQGLTLLKYMIARIMLLRAIFTAEDISEHQRMRALRDALISAHNVLVIHSALLQFTDCAFFVSPIPIQIAAMVVIYAKANTNFLTRPESPTPEHIAREDVCLALRMIPQFRWRWGRRDSHGGHPLMNFTSEAVFGPILHAFGPPNPPMLIAEHHFTEPDDTIPITSGTSPLSGGMLSPMDTLKNVQGFENRKAILNIVSSLFLGTTPSVAHPDALEIDESLLNADWRHGRLAGFSQEKMSHLDEGNVNAEGSGVPEGFDLQLLLATAPIKSDGSMIPSLRLNADWMPVVTAPEKMQEILATHPISSITSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH09</accession>
    <name>M5GH09_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633312.1">
        <property type="nucleotide sequence ID" value="XM_040767746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH09"/>
    <dbReference type="STRING" id="1858805.M5GH09"/>
    <dbReference type="GeneID" id="63682808"/>
    <dbReference type="HOGENOM" id="CLU_1326336_0_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45570">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="207" mass="23034" checksum="60CE5BC94B27AED3" modified="2013-05-29" version="1">MYTSASEYVIDFGALKADFLSYDSMNSWYGIRYAQPPTGALRWIPPQDIEKKNNYASMGAMNATVLGPECTQGVPYWSSPNGTFTFPPAGQEDWLPAYKLMFYAGTELHGATGGSVYNTLSANATTGYNATIGAYMKYWYLSFNTHSDPNAVSYSGMDKPNWPSYNNGTSFNFPAMQVNYTQIGVVHDWDASTQCDFFHGMSYVVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH20</accession>
    <name>M5GH20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cystathionine gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_73952</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633367.1">
        <property type="nucleotide sequence ID" value="XM_040776039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH20"/>
    <dbReference type="STRING" id="1858805.M5GH20"/>
    <dbReference type="GeneID" id="63691101"/>
    <dbReference type="HOGENOM" id="CLU_018986_3_0_1"/>
    <dbReference type="OMA" id="WGADLIM"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000072">
        <property type="entry name" value="Putative cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF35">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="388" mass="42945" checksum="552934E2945C5319" modified="2013-05-29" version="1">MQTTLIHGDDGYRPTSAVAPEISVSTTFRHPEPREDDEPGHPVDYDPANPTRHVYSRYTQGVSTRVEKLLGQICQGHAVTYASGLAAGYAALVHYKPKRIAIRGGYHGFHMSISVYQSSNSSVELIDLDDPYMPGDLVWVESPLNPTGEVRNLKHYADRAHAAGCKLVVDSTFAPPPLQNPFAQGADCVMHSGTKYFGGHSDLLCGVLVVQSQEEWMELWQDRTFLGSMMGSLESWLLLRSLRTLPIRVAKQSRTATELAKWLDRIAHTPKGETWDCVPGGVIEQVWHSSLQKESGEAWFKDQMKGGSACFAMHLHDPKHANKLPNLLEYFVSATSLGGVESLIEQRVISDPGANPKLCRLSIGLEDLEDLKADFRQAFGKLLRPAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN78</accession>
    <name>M5FN78_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial ornithine transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_119776</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623868.1">
        <property type="nucleotide sequence ID" value="XM_040770860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN78"/>
    <dbReference type="STRING" id="1858805.M5FN78"/>
    <dbReference type="GeneID" id="63685922"/>
    <dbReference type="HOGENOM" id="CLU_015166_16_0_1"/>
    <dbReference type="OMA" id="VEMFKIR"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF45">
        <property type="entry name" value="MITOCHONDRIAL CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="117"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="213"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT96970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="307" mass="33794" checksum="D30E72EC26777B42" modified="2013-05-29" version="1">MSEPPPPIVHPDSPLAPLTGPHRRPGLVVELIAGSVGGAAQVLVGQPLDTIKTRAQIAPKGMFKGPVDILMQTMRKEGFLALYKGMASPLIGIAGVNSLLFAAYSVSKRVVSPYPDLSIPQIALAGSMAGTINSVLASPVEMFKVRMQAQYGQPGDKRLRHVVSDMWTHWGFRKGIMRGFWVTVAREIPAYAGFYAGYEYVKRGFVKQYGPDLPFWALLTSGSCGGICYWISCYPLDVIKSRVQQADHPPKGLDYITQEMRIVMKESGWRGLFRGLSPSLVRSIPAAGATFAMFELTRDWLLKYTDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNB0</accession>
    <name>M5FNB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_91769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624028.1">
        <property type="nucleotide sequence ID" value="XM_040777023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNB0"/>
    <dbReference type="STRING" id="1858805.M5FNB0"/>
    <dbReference type="GeneID" id="63692085"/>
    <dbReference type="HOGENOM" id="CLU_987024_0_0_1"/>
    <dbReference type="OrthoDB" id="3239894at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="282" mass="31889" checksum="AC8782B3048F097B" modified="2013-05-29" version="1">MGSQIRRYGPALGFWTFLFECLNKVLKTIETNSHKGGESNALAGQNQDLLVCMLSIELEKHNQDLAWVGTLTALAVKAQDVVNQQADLGQCLPAGVGKCMPLDNWLQEELVSRYARYHPDLDIRPLHDYSAGPDTLWLSNKATFFSELCMEGKHIIKCVEEKFNKSDMLVVRLQCGTQWVGELCDVFQHVQPGLSGMQTFVLIAWLVPLQATPQHASLYDNLKELEVHFWQHNCYQTFDNDFGIQPLLLACDLCRFAAHCMLEVKGQLMWITTGLSKNGHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNM5</accession>
    <name>M5FNM5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624588.1">
        <property type="nucleotide sequence ID" value="XM_040773979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNM5"/>
    <dbReference type="GeneID" id="63689041"/>
    <dbReference type="HOGENOM" id="CLU_1647739_0_0_1"/>
    <dbReference type="OrthoDB" id="3269047at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="161" mass="16824" checksum="6EA02B16584CC0A7" modified="2013-05-29" version="1" fragment="single">MHTYSSLSIRSSSYNPSFRGSSFAISASTKPTTLLSIDTAPAPPATARGAPSIHFSHLPPSSPTPSASAPHTPTQAALGLPSTSGPTTEDKLSSLGLKPRFPRYSKPDPAHNPDPSSPALDNASILTLASTTADRRPGSVYPASRWEGWDEGEEEEGASVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNS6</accession>
    <name>M5FNS6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624773.1">
        <property type="nucleotide sequence ID" value="XM_040773869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNS6"/>
    <dbReference type="GeneID" id="63688931"/>
    <dbReference type="HOGENOM" id="CLU_3106300_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="51" mass="5593" checksum="EF1B735B77659E2A" modified="2013-05-29" version="1">MANQMGGCEQSEIAETLARQEEGNSNLVELTPLHGRVDLQIDVLERAPCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPK2</accession>
    <name>M5FPK2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="1">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_57037</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625523.1">
        <property type="nucleotide sequence ID" value="XM_040775410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPK2"/>
    <dbReference type="STRING" id="1858805.M5FPK2"/>
    <dbReference type="GeneID" id="63690472"/>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_1"/>
    <dbReference type="OMA" id="PKKFMGK"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="7"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="18647" checksum="D11ED7D8DB4922A7" modified="2013-05-29" version="1">MSATAHELIGKPAPTFTLPNQDGVDYTLHPGQGKPIALFFYPKSGTYGCTREACAFRDSQKLEVYQSTQVEVVGVSADDVKAQKKFVDDHQLGYNILSDKDRKVRELYKVPKGLLGLSDGMCRTTFVIDKTGNVRDVCDGVMNYSGHVKFVEKWLTTFSQEDKPAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPP7</accession>
    <name>M5FPP7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_17874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625588.1">
        <property type="nucleotide sequence ID" value="XM_040771313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPP7"/>
    <dbReference type="GeneID" id="63686375"/>
    <dbReference type="HOGENOM" id="CLU_1180179_0_0_1"/>
    <dbReference type="OrthoDB" id="10532880at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="26168" checksum="C9547890D273D4FE" modified="2013-05-29" version="1">MPKCIFSMHAHVKALQNKLGSMFLDRKKWAKMKLEETLNKSLPAACQALFLPDMDFVFSTEHYMCLALLEHARQTLDDPDRPGMPAEVVDKRFWYWVDQCLQNTEDQLKTKSAISKQGAEKNLQGRLCGSSCRQHGPDQHGRHTEASLAAGYRDDHGAMGFDRTWRIAGGFWDAPGSLCYSGGSRGCMQGNTGWEAGVVTRGKSADMRPKPGWPCKVLQSGRSSAFARIQTLAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ09</accession>
    <name>M5FQ09_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="6">PME-1</shortName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_119539</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Demethylates proteins that have been reversibly carboxymethylated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624356.1">
        <property type="nucleotide sequence ID" value="XM_040770815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ09"/>
    <dbReference type="STRING" id="1858805.M5FQ09"/>
    <dbReference type="GeneID" id="63685877"/>
    <dbReference type="HOGENOM" id="CLU_024818_3_1_1"/>
    <dbReference type="OMA" id="VMVCHHG"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="129"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="18"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="403" mass="43714" checksum="8001913EB7F6A887" modified="2013-05-29" version="1">MAHDLYRSALRARISKLPDLPPWDTRATQEEDVDMSTSTGMGAGEKGEREGDVDEEMDDEAGIGDLPNLSNALPRLTHRSRTPVDYTPLSAEGYFDQSLSLLLPSRELDVRLYYTPALIGPEGGNGALVVAHHGAGSGALSFASFAREVGVQSKGECGVLAADCRGHGKTRSTSSSEEGDLLLSQPDLSKDLLTLLTTLFPSPSQAPSLVLLGHSMGASVVLGVLDELLEKGYQVTGIGVLDVVEGTALEALPHMRSLLLTRPPGFPSLEAAIQWHVKNNTLRNVQSARISVPPLFVPGQNNQGWVWRAPLEKTEPFWEGWFTNLSSRFLTARTARLLLLAGTERLDKPLMIGQMQGKFQLVVIPGVGHHLQEDDPARTAGVVLEFWSRNERVFAGVKKVGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ44</accession>
    <name>M5FQ44_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623612.1">
        <property type="nucleotide sequence ID" value="XM_040769436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ44"/>
    <dbReference type="GeneID" id="63684498"/>
    <dbReference type="HOGENOM" id="CLU_1722312_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="16394" checksum="FE436B23783E4CDF" modified="2013-05-29" version="1">MRFSSRDGTTPALSPPPVNPTVLVVGTVVILVLGVVVFILLWAWSRCYRVKRREQAGDESQTAVSQALSALERMPSAACSTSQLPTYDGNRPPAYSSGSSTTRVTREGEVGHSAVCLTELERVYVTGLRAPSLIRQRSQPPAYDVSQSNSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQB0</accession>
    <name>M5FQB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623757.1">
        <property type="nucleotide sequence ID" value="XM_040769369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQB0"/>
    <dbReference type="STRING" id="1858805.M5FQB0"/>
    <dbReference type="GeneID" id="63684431"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="339" mass="37762" checksum="18B16B3DC3171305" modified="2013-05-29" version="1">MDQDENDKPKVTYHRLGNSGLRVSWPILGMMAFGSPEWLAWVKNADEALPIIKMAWDRGVNTFDTANVYSQGESERVIAKFLKTYDIPRSKVLILTKCHRLVAAVPSVQPPAARALMATRDYVNQHGLSRAAIFNAVSDSLARLETDSIDLLQIHRYDPATPAEETMEALHDLVVAGKVRYLGACTMLAWQLQAYQQVAESRGWTGFVSMQSNWSLLTREDEREVNAYCRYKGIGLIPWGPLASGLLARPLGEETERTKLTSGASFTSFETTEQDREIIRRVEGVARARGCAMGCVALAWLSGRIVSPVVGISSEQRLDEAILGDMQLTEEERECLEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR63</accession>
    <name>M5FR63_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626463.1">
        <property type="nucleotide sequence ID" value="XM_040770455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR63"/>
    <dbReference type="STRING" id="1858805.M5FR63"/>
    <dbReference type="GeneID" id="63685517"/>
    <dbReference type="HOGENOM" id="CLU_074184_1_0_1"/>
    <dbReference type="OrthoDB" id="4850648at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37827:SF1">
        <property type="entry name" value="HNH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37827">
        <property type="entry name" value="TUDOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26101" checksum="59A09C60F1E698FE" modified="2013-05-29" version="1">MPARTSDDDTNDDADDDRGMNWETLRSVLILHLSTSRPHLKQDIDIDEEVDGENVDYLITSLQEEGVALVPKDGELTLSEPEAHPFRNVLSPLLEELFGIQNGEVTFFCSCVIDAYLFSTRSVQADEASPTQRKPATCELCARPMPLTAHHLYPRSEHSKLLKRTQLSKAQLQQTLAFLCRPCHSAVHKMLDAPTLAREYASVERLIAHEGLARWAAWAGKQRVVGKGLRTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR66</accession>
    <name>M5FR66_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_118868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625006.1">
        <property type="nucleotide sequence ID" value="XM_040770678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR66"/>
    <dbReference type="STRING" id="1858805.M5FR66"/>
    <dbReference type="GeneID" id="63685740"/>
    <dbReference type="HOGENOM" id="CLU_1331923_0_0_1"/>
    <dbReference type="OrthoDB" id="18703at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31109">
        <property type="entry name" value="PROTEIN FAM207A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31109:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22941" checksum="E83E0169248B10F3" modified="2013-05-29" version="1">MTPHICSSFIMPKAQRRARTVAHDPPLRPKKTLPSLRDFAVNERVEKVVSGSKADQTGDAILAENAVEPVQTPKKERVAARHERLLNRLNILSNNSPHAPYAFSKSALKRYKRKAKEDIPLSGLGAALAEVGEEVQQEQEQRAEQKAKEGKIGEGKERGLSSKQRRKAVETEAKHLNAVLKDPTFRANAFAAIRQHTANTLEKRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRM4</accession>
    <name>M5FRM4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626723.1">
        <property type="nucleotide sequence ID" value="XM_040768848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRM4"/>
    <dbReference type="STRING" id="1858805.M5FRM4"/>
    <dbReference type="GeneID" id="63683910"/>
    <dbReference type="HOGENOM" id="CLU_016785_6_0_1"/>
    <dbReference type="OMA" id="YWHDMEF"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="133"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="326" mass="37491" checksum="3079328C60822E56" modified="2013-05-29" version="1">MEQVLRKLAKEYQDLNGAEFTRIEGRYIQDSDWPRWQHIGRPVLIDDYFTFGEDEGWTDAWLREVFGSIPLSIAVTPDGAADALKEHSDGRTYFVEPLTEQQDITSFLASFGQDDATHQEVRYLQSQNGNIYNSSIPITELHALRQHIPLHVPFVHHSLGVEPDAVNLWIGDKRSVTSLHSDPYENIYHVIRGVKHFTLFPPTETCFFPDHEYPHATYTRTEAGLQLTPSDPAQHPPVRWLSFDPDNPPEGTRPLFITVRGGQTLYLPAGWNHHVRQAGLGEQGQGVCVALNWWYDVQMEGMTWVWLAFLRKGIRYLENEEEGRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS50</accession>
    <name>M5FS50_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_96400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625516.1">
        <property type="nucleotide sequence ID" value="XM_040777367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS50"/>
    <dbReference type="STRING" id="1858805.M5FS50"/>
    <dbReference type="GeneID" id="63692429"/>
    <dbReference type="HOGENOM" id="CLU_007183_0_0_1"/>
    <dbReference type="OMA" id="NTWHEAP"/>
    <dbReference type="OrthoDB" id="19394at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="16"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="677"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="828" mass="93256" checksum="2FCE7E6C6BD84366" modified="2013-05-29" version="1">MSSLPTASKDVSDQPGKNAVTDPVMRERMQMDVDRKMRFYGIIEAFRNGKMPDNQQIDETLRYVESQSPIDESQLSGEGRRLIADTRDIIETARLIVKEKNADELFQNFVFHTAYVDPGRSKIEGDVLPVDTQTVKADGQQALVHLRTLLTLFLTNSEFRKLLNDVGLIGRDMFATGAAKIAEAARPDAERMAQVDDAAPADQWQGANGKVHGPNETPALQVNLPGGRSIIQHPKEDFGAGATVRDKDGKEMSGAEAANKVQAKKDELVERGTQEAQDVQREVNGNTTADDTSAQAGVAKRSLKDKLLGLKDKIPQEHKDRVDEHKDNVKHFFEENFPEERRDQFIWRMKKVVVECQKHDDYQGAMNWFLNFLETYHAHGKALAETGVRSAGHVAEDPALKQAVLELRTLLERFANNTSLDGIINATQDLYNDAQNDPALRAWFEKLDAFVRRTLLQPAYVLQPQYNEEGRALLDEGKGFFDVKYRAHKDNLFDQIEAWFVAFGEDRLNKRFGEDWSRLTKDILFDDEGNLAFKPHLWNDIRHVILPQIIDQVGYIPIPRVEYTDPTVDLVIENLTLQGANILPNIIEVEAQNYVKFSPYSTIPDVHHHELILTLGQMQADMRDVAFCFKKKSGFPRLSDHGLADVMLGGTGLTATVHIASASKDSSSVFHVQNVNVKIDTLKFAIRDSKHDTLYKILRPLATGLIKKQIQKAIQDAIRTGLEYVDGQLVTVRDRMNEAKAQDGVSRTDVLKEIFQRKKEEAQSVKERKSEFKIDTSRNSMLLPDVGYEKGWIQKVSDRKDAAAAGEGWHSPAFSIINPNATLKSHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS82</accession>
    <name>M5FS82_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_110566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625561.1">
        <property type="nucleotide sequence ID" value="XM_040769081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS82"/>
    <dbReference type="STRING" id="1858805.M5FS82"/>
    <dbReference type="GeneID" id="63684143"/>
    <dbReference type="HOGENOM" id="CLU_1722310_0_0_1"/>
    <dbReference type="OMA" id="CESKLKY"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="16924" checksum="D9CE975A17736E24" modified="2013-05-29" version="1">MDCPSDIFPRRRTMIERLPFVQGCFQEGLRVYPSAHMFTRAPTEDTVLQVPSRQGGGVVPIRVPAGQVVTLDIVGMGYNPRVYKDPKSFNPARWLDPATEPLLNFSYRPRVCIGKKFAVVESVCLLALLLRDYKIEPVLKGGQSIAGCMQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSE7</accession>
    <name>M5FSE7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627238.1">
        <property type="nucleotide sequence ID" value="XM_040773176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSE7"/>
    <dbReference type="GeneID" id="63688238"/>
    <dbReference type="HOGENOM" id="CLU_1767990_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="16702" checksum="3C01986FA9E813BF" modified="2013-05-29" version="1">MARQPHPQPDSPQSTVCVAGSTRPLPVTVMMLYPAHQFLQSAMDPDAISLHPRWNDTLRRMKLLLFVQMVNQVTSELHYRTIMSSVNQPGQDATSHSLRRMSTSEIRKLAAALVHEMERRFPILTSAYQRTDRPSSPDSTPQSYQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSI2</accession>
    <name>M5FSI2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24373</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625741.1">
        <property type="nucleotide sequence ID" value="XM_040773662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSI2"/>
    <dbReference type="STRING" id="1858805.M5FSI2"/>
    <dbReference type="GeneID" id="63688724"/>
    <dbReference type="HOGENOM" id="CLU_007931_0_1_1"/>
    <dbReference type="OMA" id="MDLQARK"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067132" evidence="4">
        <location>
            <begin position="27"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="787"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="853"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="883" mass="97295" checksum="7A10F562E1246092" modified="2013-05-29" version="1">MMPRCLCRRALQLLLTVTLCVYVTRAAEPEQAWDTAKNRGTAVPQMKEAAEHDIDDAGPVDEGTRAYHAALQALSPLYSSDEAEMLASQQSISFLRSFISRRAGPVDFMLRILSNLHIPGLAGSRSAPKGEIRGRGAKVLDLLSYAVEQGNMDALAMLGEVSMFPPTSIPMNLTRAFEAYTTHATLTGSPFSQSLLGFFYATGYGGVVEVDQAKALLYYTFAAVGGDQTAEMALGYRHWAGIGVPEDCMTALGWYESAAERAMAQFLSGPPGGRTLLLYPTRLSDLIGGVYGPGSSVASTGWNANRAAVRAGQARAAGETWQDILEFYQYHTDQGELEYTLRLGKIYYHGTLYIPSAGSSAGGDAVGAVRQDYRRAAQYFVRIARHMWPRDSLKAPLANLRELDERSTILVAQACGYLGRLYMRGEGVRQDAKIANMWFERGAEYGDRECHNGLGIIHKEGLLGSKDDAKAIHYFAGASGADLAEAQVQLGRYHLLNGDSVSATQFFDIALRHGSPFEAYYYLAHIHASMARAVSLGTTSSGSCAVALSWFKIVAERGAWDNDWMGEAEKRWNTGHEQDRKIAMLYWAVAAEAGHEIAQNNIAYLLDKGEDYGMTNHTSSSALLYWTRSAAQNNIDALVKVGDYYYHGLGIADALIPEHLEKAAGYYQSAVESQLSALAMWNLGWMYENGLGIPQDFHLAKRYYDLAMETNPGGYLPVTLSLIKLYARSIWYTISGGKNHGLSLWDLRDATDEHWYLGKSKEDAKKARRNSIDGGIGERVGEDAVQWARDRRDRDEQGDFGPEDHLFSGEGEDGESVEFVETLLLLILCGLLAWLIYVRTQWATRRAVEERRRRDAAGQPDGQAPNHRNAVGRGNAGLRDVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSP8</accession>
    <name>M5FSP8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mago nashi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625147.1">
        <property type="nucleotide sequence ID" value="XM_040773808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSP8"/>
    <dbReference type="STRING" id="1858805.M5FSP8"/>
    <dbReference type="GeneID" id="63688870"/>
    <dbReference type="HOGENOM" id="CLU_109497_1_1_1"/>
    <dbReference type="OMA" id="IRKEMWI"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1560.10:FF:000001">
        <property type="entry name" value="Protein mago nashi homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="17060" checksum="16102FA37871108C" modified="2013-05-29" version="1" fragment="single">MAQSLDKDAFYLSTGHAGRHGHEFLEFEYHKGRLRYANNSNYRNDQLIRKEMCISPIVVGELKRIIETSDITKEDDANWPKKSIVGKQELEIRIGNEHISFETSKIGSLAEVAESEDPDGLRTFYYLVQDLKCLIFSLISLHFKIKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT87</accession>
    <name>M5FT87_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PLAC8-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626126.1">
        <property type="nucleotide sequence ID" value="XM_040770508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT87"/>
    <dbReference type="STRING" id="1858805.M5FT87"/>
    <dbReference type="GeneID" id="63685570"/>
    <dbReference type="HOGENOM" id="CLU_1331922_0_0_1"/>
    <dbReference type="OMA" id="GAIDICC"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22697" checksum="0B132DCE0723709B" modified="2013-05-29" version="1">MSKPPSRPTPVYAQPQRKEEMLPLPPRLLQPPTYHPSRNGRAEWHTGLFGCCGAIDICCPALVCPCWVYSRNRARLRHLSGTGQPLGRETSAWDGNCGLYALLTAVGCWGWVLEGNVRRGIRERYNIPGDSCTDTLTTLLCPPCALTQESLELSIEERRLRQERLQGTAGIYGPMDDSVLEDPVGCGEVCCCCCRMAAGGGRGCRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTF7</accession>
    <name>M5FTF7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_116803</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627818.1">
        <property type="nucleotide sequence ID" value="XM_040770266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTF7"/>
    <dbReference type="STRING" id="1858805.M5FTF7"/>
    <dbReference type="GeneID" id="63685328"/>
    <dbReference type="HOGENOM" id="CLU_287577_0_0_1"/>
    <dbReference type="OMA" id="HKSASIQ"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="501"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="704"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1016"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="736"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="764"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1044" mass="113865" checksum="9973A0CDD6C37DC7" modified="2013-05-29" version="1">MPPIGKSTQPARGPGGRVRITNRSRLRIYHGSIDADNVVLEEDGSGKGMSTAGVDAEDANEHHLQVVLSLQTLDGEQGKEVQKAHIPVPDATGVVSNYESLYAGPKGQDTEGYLKCSDLVDETLEGGFIDGYTYDLDEEDLAWLEKNTQAAKNPYTTINGARSMRKKLGKDGTEAKDAPPAPFSISEPEFELLMGLFDMLCDNVRPTLHADLSTIPVLADFEETLTHELAESFFAMYDRPSNLPTPEQVWLLARAIYPHWKERKIEREGLRVMAQLNTDETSDGDAFVCFRRRDPKPVRKTRRSDTSQLDRMARLLAEMEQAEDISHNALLREQKKGEQLDAEHKVFDARRRFATVRVHHPEFGSVMEDEKYLFSKDPTAVVAPKILLTVGARKSSSEAGSRTAEHGDADAVEVVQAKFEENYRKRKLEDDGWDNRTDGAAQPGWKQIGAFMFSRVPQVPVPPLVPQKAANETERERPTVGFRTRRGRGGFVRLDRLLPHRSRTPAQDNPFTRKPLSGPAFNPQQRSPSKVARDLAGDGLRTAPDVAANLSDPNTPWSTMSSKEYVKDNFFKNGPVYNNPEMELNGTKVVDDFDLSYELFRADLFDPEHPHPVRSNMSYLAQALDYNREIRTKELKEAPLFAPFKAPTSNALRLTTHANNAATPGTAPPSATQLPPNAANIARVGQQAQAQQAAVAQAMSQANQTQQRFSQQQLSGTARAPQTPVNHASTATSASPTPPRPAPHPQQAPVPTSMSVQAIHMPNGNVSSQTNNTAHPGSSVSPVQQLQSNLPLNGDLNHALPRPASAMQAGVQRPPYPGLPMPPSGMPANGMPNSMAGYRQANAAAAAAYAAAYANNPQMMAAMQQYHRQLNGQKSAYASSPMVGGMPMQYQMPGNFGALGVDVNNMNLSLNSQNMQLKLPSGRNRPNNMHQGMNGMDMAGTSQGTNGVPFLQMGIPPIARVPSANGQKHLLPVPMQDPNGTGVGVNGQTYMQYALPSTSPMLQAVGVLPVPTPMLRPSKSPFDPANSRPGSSSPLLHRPQSVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUC0</accession>
    <name>M5FUC0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_116506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628213.1">
        <property type="nucleotide sequence ID" value="XM_040770216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUC0"/>
    <dbReference type="STRING" id="1858805.M5FUC0"/>
    <dbReference type="GeneID" id="63685278"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OMA" id="ACRRIMI"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009384">
        <property type="entry name" value="PRK12743.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="275" mass="30013" checksum="6BD568C5E7DE8F7B" modified="2013-05-29" version="1">MSTSTTSKVAIITGAESGIGRQIAYELAERGYDIGATWFDSQEEGQKVCERVRAMGRRAELLHLDLTVLPDSESLVDDFIKLFGDLDLLVNCAGVGRRGTILEIDWNDWRRTFSICVDGPFLLSQRACKHWVAHNRPGVIINITSVHEHTPHPRSMAYNSAKHALGGMTKTLAVDMAKYGIRCVAVAPGMIATASNGMDEDKSFEYLVRGLPAQRPGHPREIAKLVAFLASEDAGYITGTSFAVDGGFLVTNAQFPPPGLQVEEGGKEVPHPPWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUG9</accession>
    <name>M5FUG9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_116558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628283.1">
        <property type="nucleotide sequence ID" value="XM_040770224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUG9"/>
    <dbReference type="GeneID" id="63685286"/>
    <dbReference type="HOGENOM" id="CLU_562603_0_0_1"/>
    <dbReference type="OrthoDB" id="3353816at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="55260" checksum="6F8EE454D764E3DA" modified="2013-05-29" version="1">MFPLHYRAFTWPTHDGTWYTGSTSVKDPNPFGELRVVCEEFLSAAPHRWDAIRAISIDKSGTREAPRFMQDYVRGDGFVLPELPAAMYENMAQLANNSFVIGQRVDARKILMTDKVDNILCRMPQLTSITWRWFPPQLDSPIWPVLDTISGLRKVTFVFNTHFATGFSSIVLSSIIARLVQSIANCKMLEVLQINVPIARNVYHDPTWKVDPILELTWPFLYRLSLSHGRITSAQKFMDFLTRHNRLKELSISDSLVPSIRGKNDQLPRIQDMDLANFRLAKALLPKTSKSTLDPCPTHALRIHSSLSRTDFAALCDILPGIANFLQKLSISLTETSDQDIMTVIDVAPNLVRLEISAREVITVLTGVKRLRSKQTLKRQNWGPMRDWKDLKFPIDFMNHLTPWATAFRKAPRLESLLLRCLPTSASHSQPSMYDDTKSVSLEEAFRAILDVSRVESHMLVGRDMGLEITCYRKEAQQSMEAKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUS7</accession>
    <name>M5FUS7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623924.1">
        <property type="nucleotide sequence ID" value="XM_040767656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUS7"/>
    <dbReference type="GeneID" id="63682718"/>
    <dbReference type="HOGENOM" id="CLU_839439_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="331" mass="36392" checksum="89B898F495815FE5" modified="2013-05-29" version="1">MGLCVSESTLSPEHILPHHPLYLALVKPCWGSSASPDDPCWPQMIKSSVNPSTPPLPTRAGLLDTPTRSLAKNGSHANNTSAMRRETSLSTRHTRAGPPPTPPATNDKPQPQMESFVSFGDQHAVYNPLTSSAPIYVVPDPNGQGYFFVPPQEEGVVDEMTWCQQIQVQVPLEATPSSMGLPLPESESEGTVTEAALPESLVDRAIEAGRALQACPDIGPIHLQLSKLISRLLDCKYSPGATYISDGLAKRLNKFCNWCYELSSKLRNGHTHHWSTGEVEQLKDFLSRISSNIQELQPDPLFLEVMVEKRQVDACRWTGREADKFAARGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV10</accession>
    <name>M5FV10_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA-guanine transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628503.1">
        <property type="nucleotide sequence ID" value="XM_040777277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV10"/>
    <dbReference type="STRING" id="1858805.M5FV10"/>
    <dbReference type="GeneID" id="63692339"/>
    <dbReference type="HOGENOM" id="CLU_019834_0_0_1"/>
    <dbReference type="OMA" id="FDARWAQ"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="31"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="281"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="56851" checksum="2D1E36D47A2D1667" modified="2013-05-29" version="1">MSGATARPPPVLSFKLLSVPATPFSPRLGLARLIRSSTEVIDVVTPGLFLHTSRGHVPHLSVDHISLMAKQMPWLHASFEGFLETLPPTPTLQPGPQPLHTFFGLPAASHIISLSLRDPADVQERPPDGDDYLSSMTIRGVRKIEPSFYRSYVSCVQPDIIIALSDIPFTLPPFSQKRMTKSIDRTIRWLGEILKSRPSMEITDNIRGNNIFVSLVGGTNAAARRAFSQNLLGPLEEGSNLSSVRPQTIPRLDDHISGYVLEMAQLRLELSASLSCGNDSSSTKEPTQAINQLLKASLSPLPADKLRVVHSSISPHEMLRLISLCGIDLFDSYWAQKAADWGIALDFSFPVSTSRDDTGPTRRSDGKRDVGHNLYHTGYAFDFRGLVGGPMHGCSCLACAPSFTKPIPHSSLEFVNDGCEEDAPAFTRAYIHHLLHTHEMSAHALLVSHNITVLQDFFAAIRSTLSADAPQFDTEVARFETEYDGDMRIIEEGRRAWEEVDCARGKGRLARERGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV76</accession>
    <name>M5FV76_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_102576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624094.1">
        <property type="nucleotide sequence ID" value="XM_040767642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV76"/>
    <dbReference type="GeneID" id="63682704"/>
    <dbReference type="HOGENOM" id="CLU_1434407_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067355" evidence="2">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="21438" checksum="E49121CEFA6B38B4" modified="2013-05-29" version="1">MRIPVILFLALFSTSVFAHPVQTFTSELSSEDGSPWKRSPVNPTEEQRRTEQGAHLWRASGLANDFVQTHKKNFGQARTARHAARLVMHGAQKDHTQSAKTVQDERTRLGRKTPGSQAFKRSSNRLKEAHNKHTTNQHALMTATSDYQKTQETYDEAEKDYTAAKLIKSAVDEKIQTHVDNSQRPPPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVB0</accession>
    <name>M5FVB0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_81115</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627096.1">
        <property type="nucleotide sequence ID" value="XM_040776493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVB0"/>
    <dbReference type="STRING" id="1858805.M5FVB0"/>
    <dbReference type="GeneID" id="63691555"/>
    <dbReference type="HOGENOM" id="CLU_041220_2_3_1"/>
    <dbReference type="OMA" id="GMFQKEV"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 9 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="12">
        <location>
            <begin position="49"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="318" mass="35794" checksum="220C55F68FB13394" modified="2013-05-29" version="1">MPRATSQKFARVHEPSAAALKSKGEAVGNRNPLFNTERFGQHILKNPGVARDIVDKANLRPTDRVLEVGPGTGNLTVLILEKAKQVTAIEMDPRMAAELSKRVQGTPEQRKLNIMIGDFVKADLPYFDVCISNTPYQISSPIIFRLLSHRPLFRVAILMFQREFAMRLVAQPGSSLWSRLSANVQLYAAVDHIRKVDKANFRPAPEVDSSVVRVVPKDPPPPVKFEEFDGLTRILFTRRNKTVHANFQAKGVYKMLEQNWKTWCAETGQMVEDGVDFKQRVDSLLEETGYAENRAAKMTVDDLLKLLSAFHDIGVHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVT1</accession>
    <name>M5FVT1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trimeric LpxA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_100958</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627361.1">
        <property type="nucleotide sequence ID" value="XM_040767507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVT1"/>
    <dbReference type="STRING" id="1858805.M5FVT1"/>
    <dbReference type="GeneID" id="63682569"/>
    <dbReference type="HOGENOM" id="CLU_900228_0_0_1"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF23">
        <property type="entry name" value="ACETYLTRANSFERASE C18B11.09C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Maltose/galactoside acetyltransferase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="33768" checksum="14D07710D8E2B91C" modified="2013-05-29" version="1">MPAASQKDLFQIEQAKGLRNVPWCDQYERMISGMLYDAMDATLASARFRARKLMNKYNSHFPDDATAASLTADRTAILNELLGRAGDGIYIEPPFSVDYGSNISFGDRFYANFYLTILDCGLVTIGDRVMFGPHVSIFAATHEVEVQSRRENIEYAGSVLIGDDCWIGGHVTILPGVTIGQGCTIGAGSVVTKSIPEWSVAILTSFRSVPRPAHDCFGLSSIGTPFGDKASVIPSLTSHEFRHLQVYDVKTILSVCLALPAILAVQPNTLVRCDFTAALAVMPERLLQALEQINTEPFSSEAGRIKWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY7</accession>
    <name>M5FVY7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_30898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY7"/>
    <dbReference type="STRING" id="1858805.M5FVY7"/>
    <dbReference type="GeneID" id="63689404"/>
    <dbReference type="HOGENOM" id="CLU_012494_3_0_1"/>
    <dbReference type="OMA" id="WDKSARP"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050466">
        <property type="entry name" value="Carboxylest/Gibb_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024:SF242">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024">
        <property type="entry name" value="ARYLACETAMIDE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="53"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="217" mass="23742" checksum="9E44B2A5F61ABCF6" modified="2013-05-29" version="1" fragment="single">KPVHLNFHGSGFIFPSLGSNHLACTLLARQTGAIVLDCDYRKGPKKNEEGRFDGRVTVSGFSAGGTLALALVGNLEEGVQVQGVTVFYPPVDCSVPFRKKVPPPPGPGGPNPIGDLELMRLAYLGDWNELRDPRLSPAFCEPGKFPDKGRTLLLSVEQDWLDAECRAFGERLDEAGRGVVRIWEKGVGHGFDVFCSEGTGEAERRDRVYREMVLCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW28</accession>
    <name>M5FW28_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628968.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW28"/>
    <dbReference type="GeneID" id="63683439"/>
    <dbReference type="HOGENOM" id="CLU_095741_2_1_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054208">
        <property type="entry name" value="DUF6914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21858">
        <property type="entry name" value="DUF6914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="17324" checksum="3D3A54F6031FBA22" modified="2013-05-29" version="1">MPIPSSAIAPSMYIVLTSHGFLANGYHWLILTTYMDGTCIAFHATQDPGWCYQQKEWQMITSMTLVVAILISKAHLSTSIDQILQDIPMETPAAEVSVTFSCCIWVKEAACHLVTGHLMTCNDVNTLEGEVIAAANQHADSIMIGGTGAVYRSRACGTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW53</accession>
    <name>M5FW53_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628998.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW53"/>
    <dbReference type="GeneID" id="63683449"/>
    <dbReference type="HOGENOM" id="CLU_1695408_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067309" evidence="1">
        <location>
            <begin position="22"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17662" checksum="23E7C36A836DD007" modified="2013-05-29" version="1">MFVIHITTFVSLLALSWLVTAAPVFKTDNQQLATVEARSFDNLDLGYGVRHLQDRDLDLHNEDDLQKRETDEDSSWMELRSDRDDLQRQLEAEHQAAVRSARRTQERELRAARRAVAISRVIGKVQDFCRAATCRPPREGRPGIGKATNGFGMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW87</accession>
    <name>M5FW87_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629043.1">
        <property type="nucleotide sequence ID" value="XM_040771117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW87"/>
    <dbReference type="GeneID" id="63686179"/>
    <dbReference type="HOGENOM" id="CLU_1875368_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="14954" checksum="3D0680F9D8363AA3" modified="2013-05-29" version="1">MNHLLNTPPIRPRREETKEGKEHTVPSQLSQIFTTRPDPEPFTAEGQRLRAQQQMDLELSGEHEKARNKMEKRQAAELRTASRAVKVAQVVGKVSDAWKNFTGQPERVKPVTPGNQGGSGNQGGSGNQRNQGGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWE8</accession>
    <name>M5FWE8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 16">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_119374</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624614.1">
        <property type="nucleotide sequence ID" value="XM_040770775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWE8"/>
    <dbReference type="STRING" id="1858805.M5FWE8"/>
    <dbReference type="GeneID" id="63685837"/>
    <dbReference type="HOGENOM" id="CLU_031067_0_0_1"/>
    <dbReference type="OMA" id="QHYLARC"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038074">
        <property type="entry name" value="Peroxisome_assembly_p12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 16" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="23"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT97716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="370" mass="41932" checksum="D05FF210BD2B2F9B" modified="2013-05-29" version="1">MDFYADIGASDTQRPSLFELLAQEQLRDLLQPAVKYVLAFFAQRYPRYLLRIVNRHEEFYALLMLVIERHYLRTTNASFSENFYGLKRRKKPIFEIERANIAAGGAGDHETLTPRARLLSLLFLVGVPYLRAKAEDVYEQLGGGLDPDLAGAETSQPRQISTSQTARARMLAAAKQAFKVAYPYANSAYHLWLFAWNIAYLFNKTSYYRPWLALIGVDLRRMTVEDMRMSGVVPSAATQSQPLVQRLLALFRPSTILSSLKQLLPLSLLTLKFLEWWYSPASPARFIERTTQGPPIPPPAPLSPHPKGVGVDPEKYGQCPVCKQEIVNATALPTGWICCYVCAYQWVKEKGTCPVTKLEVRVDELRKILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX54</accession>
    <name>M5FX54_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin AspB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_53339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627906.1">
        <property type="nucleotide sequence ID" value="XM_040775166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX54"/>
    <dbReference type="STRING" id="1858805.M5FX54"/>
    <dbReference type="GeneID" id="63690228"/>
    <dbReference type="HOGENOM" id="CLU_017718_8_2_1"/>
    <dbReference type="OMA" id="RSNPMGS"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000196">
        <property type="entry name" value="Cell division control 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="59"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="395"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="437" mass="49862" checksum="167812274C175437" modified="2013-05-29" version="1">MRDAASSINGSANRAASLVSQQTYPASNIAPPQVSRKQLMGYVGFANLPNQVHRRSVRKGFQFTVMVVGESGLGKSTLINTLFSTPLYPAMELPPPSAEPPKTVAIESISADIEESDVRLRLTVVDTPGFGDFVNNDSSWKPILDSIEQRFDAYLDQENRVNRSKMVDNRVHACLYFIQPTGHALKPIDIEFMRRLHTRVNLIPIIAKADTMTDEEVTQFKARVLADIRYHNIQIFQAPTYENEDEETLAENEEIASRIPFAVVGSTTVVKTPDGRTVRGRAYPWGVIEVDNEEHCDFVKLRQMLIRTNMEELREHTNLVLYENWRTEKLIAMGVEQDQSVFKEVNPAAKQAEERAMHEAKLNKMEAEMKVVFAQKVMEKEAKLKQSEEELYARHREMKDALDKQRAELEDKKRRLESGRPLTPEKTNTRKKGFLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXC7</accession>
    <name>M5FXC7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625029.1">
        <property type="nucleotide sequence ID" value="XM_040770683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXC7"/>
    <dbReference type="GeneID" id="63685745"/>
    <dbReference type="HOGENOM" id="CLU_442816_0_0_1"/>
    <dbReference type="OMA" id="GLWMGAW"/>
    <dbReference type="OrthoDB" id="2152680at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="63175" checksum="ECFC4CFA79A4AFC4" modified="2013-05-29" version="1">MSLLSAESVVETTTGPDHDICAVFKTAFHPTKGNIIEWSVKTSDDISLDGIEFSTLPSGLHVVDEDVIYFTKGAREGVCVFRRTKTDAEGQRGFKLGALGVLLEESTRSRPWLHVENLRRMADLQQDAIDPKSLSHYFEEYQVSDVPQPVEEDLEDEVKQAGSSHPYFHLSSFLRQLGPTSLLLYKYALARRRILIYTHPAVESACQLAWCIQAIADMGTFEAGKGRGEKVPVLGLVGLIDIDRLKAEGEKGRGWIACTTDAIFLERPQLFDLILDMTTTPRSASSSSTSSEPAPPPRPNFYISTRIPHPLKPKETHILRPAHFAWSDLPFWSSLERYIPPEGHPVNKSWQDPWQMYEDVCMMCAGMFVGSWRSSGVRLEGEEADLRRIQTRPKVNAGGHHRSPSGGSVRSAPVGEMSIPPKRNAIEALRRASGATSEQLSATSLPNPDTGVGAESESPHLDNVTSALLLLSQFQANTAALLASLSDLVMPPLTPDVPATTPGPGARPSPSPSGKRRRPSPRSVTLTPRDLLALKLGPLSAGDAKFVEWLALERLGMRVSVRRGWWDLSLGLLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXF9</accession>
    <name>M5FXF9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629570.1">
        <property type="nucleotide sequence ID" value="XM_040771096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXF9"/>
    <dbReference type="STRING" id="1858805.M5FXF9"/>
    <dbReference type="GeneID" id="63686158"/>
    <dbReference type="HOGENOM" id="CLU_006580_0_0_1"/>
    <dbReference type="OMA" id="MQSKYDE"/>
    <dbReference type="OrthoDB" id="431454at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1158" mass="128205" checksum="5810254F335965BA" modified="2013-05-29" version="1">MNTEPNTSSPRRSNGRFRAKVDAAKEGIQDALEKLAGISDVLEHQNKRCEQLVQKAALVQTRILERVSTAPATDEAATRLRADLSKAVNDIHALITKRDGKRTLTRYQELVEPEIHMLEEALDSLLAKFSVITVVHVSERVDRLEQQRDGALVYQVPVDLPLLVMPPKPVVFNGRDELVESIVQGLCEAGNCHIPILGPGGIGKTAVAAAVINDGRIVTKYGANRIFLSCEGVPTCDGIVSMLAVNLRLHHDTDARRAVFAYLTSLSRVLFVIDNAETALDSEDRANVENWMGTIAGEAHISLMITMRGSSPPTTVRWRNVFRDPLLPLTLSASRATWLAHGASEDAELDTLLNMLDGLPIAIMLMATLDRVAKPAELIDRYESEKTSLMSNGGTTRLTSLEISIRLSLNSHTMVNSPGAADLLSILCLLPDGMLVAAMTKALPSLSKHGSVLVKTGLAIREKERIRCLAPIREFILKSGKLPSAPLADLRLFFMNMTKRVDDLGGEGSRDAIGCLSAEFSNILFLLRHFWIERSGDAIDDTWRATLTNSTFNISDFSTFARLGDCSDLLGLAFKQLEIEEDAENTTRCIQLRGYALEARNQYDEALRRYDEAKERYQTSGNFYRVAQCTQSIGDIFCMQSKYDEATAVLEEARVELSATGSRLGVAQCTRSIGDILRMQSKYDEAAAVLQDARTEFLSIGSRFGAAQCTQSIGDTFYMQDRYDQAAVVLEEARVEFRAVGFRLGAAQCTRSIGNIFQMQSKYDEAATVLTEARVEFRAIGNRLGAAQCTRSLGDIFRMLDKYDEAIAVLEEARMEFRAIGSRLGAAQCTQRLGDTFRMQSKYEEALTVLEEVRVEFRAIGSRLGVAQCSRNIGEIFVAQSRYDEAVTVLEEARLEFRAIGDRVGAAQCTQSIGDTFYMQDRYDQAAAVFEEARVEFRAIGSRLGAAQCTRSLGDIFLMLDKYDEAARVFAEAQLEFRAIGERLGVAQCTQSIGDIFLMLDKYDEAAPVFAEAQLEFCAIGERLGVAQCTQSIGKMFGVQSKYDEATAVLEEARLQFRAIGNRLGAAQCTQTIGEIFRMQGQYQEALARIEEARVQFQAIGQLRSVDECVSSTREVQAEQARLAGHKRQQDTGILRSRERSDGVARLWRRLRHGTPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXL5</accession>
    <name>M5FXL5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_111211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625139.1">
        <property type="nucleotide sequence ID" value="XM_040769194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXL5"/>
    <dbReference type="GeneID" id="63684256"/>
    <dbReference type="HOGENOM" id="CLU_392787_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067279" description="REJ domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="74219" checksum="427909E5646E40D0" modified="2013-05-29" version="1">MPRVFDLVVVLFCLGNTGVAGVPQHGPLVGEREWREGRAAQADEPGGGAFNNGMYTPWTDGVTSTVGGGASGKGSATSSAAPSTSTSTSTTMSSAIPSTSSSGSTSSSTDTAPVSSASSSSPSPETDSASSSSSSSSSSPYTSWLDAPPSPTPTTWRLAMTLSSRPAYTYALGPTSTPSASASGSANTSTLGGFNWAYLAVPGGILLLALVGYWFGRCYWRRRRERERGSVYSAEQLVWDSPAYPYLTGEGEREGEAWADEKLDSGEEKGWKEHLLSYSSTDIFAEEPRAVYLRFSGQEYAFSPNPSTWGSGYAQLVDTPARNKSTRASTRSKSRGNMDKLLKSPGWFRTPLQGETSLFSPSPTSTPARKPSWFRTPLYAQERSPHVVPSVAVADALRRKVSWFANAAEGAAGAAGVGAGGSVGAVGRLWGPRVRPGRAGEVGVPLPMPGAVQGYATLGYANAGVPVPGAHATWQQEHAREQGHAQDHPREREREQEQGREDESEKEERVRSLLLARREPYRLSLPPPPPQASYHPVPERVLLPRPHRPYQPGMGAEDPFLDPASSYSQSSLNTTITATTTTTTSSTTTSRTTPTRTTTSLTPTSTANDLSYNPPTPLTLSALSSPSVYSLASPPPPPAAYILPPSIPTLEAGSEPLSLEGSPPRGVLGGREGHRTWGRGRGLEEGEQWDVPVGALALGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXX4</accession>
    <name>M5FXX4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBM21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629795.1">
        <property type="nucleotide sequence ID" value="XM_040770088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXX4"/>
    <dbReference type="STRING" id="1858805.M5FXX4"/>
    <dbReference type="GeneID" id="63685150"/>
    <dbReference type="HOGENOM" id="CLU_343229_0_0_1"/>
    <dbReference type="OrthoDB" id="1881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001069">
        <property type="term" value="F:glycogen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="300"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="717"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="825" mass="88526" checksum="A3056CC626476EB6" modified="2013-05-29" version="1">MSLAEASSTITLGPPPPPAPGQYARNHRRSRSSQFFTEERTQGAFSPLPPLPRRSSVRTRRTSSPIPIPGAALRADSPSPDNALGLVPGPEETVSNEVAESLVDSSTVPFPSIGPLSPDPTTAPPKPAPPLVAHLPILSLPERTPTPIPVEPTPEPSSPQSAPEPPSPKFTPQSSPITLKNGRPLKPSLKSRSYSTPHLASLPSHTRAISAPATPNYVPKNVHFAGEKEGLEHVVLFLREQRPIAVSHGTPEDTETETENDAKPASFTFPRLETPPPRDKVLLDPERTSPVPNASSLRLQDEMSRYPVMLESLLLPQSNPLVMRGTVIVRNINFNKQIAVRFTLDDWQTVSEVSATYVNHLPSLPPPFSSHSPFASLDNKGWDRFGFQIRLEDYERKIEDRTLFVVVRYGSEGQEWWDNNDGANYRVRFVRAPPSAPNTPSSAPSGTAALSSAPGPIPTPQAVARSSTASQATFIPVSEPPRRSHSFNQLNLKLLNYAPPTSPKSEHTNLTPKASLFLAKDKEREEEADKKAQAQLVNGSDTPPLLESKLANAAAMEKFSGARKEVLHPTSSLGAEFEAEKAEREREKENGAPIAPVFTLATLNSIPNPINRIGSPALSVDRSATPRPASPRTVPNGLPSLVPARPASPMHIPVPFPGAGTRRLVGGTNSPGSSSEDLSKLAQRRARLAGSGSGSDGSPRTASPRPGSPHLSLSDGTTTTTPATPVISTTVNGAAPTGEQPQQRRKLFTMEPMTPPSSSEGSPTQSMPSSPLQSPPPRLDRSERSYEEFLQKYCFFRGPNDMGTPPMTAGSRNSSAGRGLGQVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY91</accession>
    <name>M5FY91_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_95493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627682.1">
        <property type="nucleotide sequence ID" value="XM_040777300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY91"/>
    <dbReference type="STRING" id="1858805.M5FY91"/>
    <dbReference type="ESTHER" id="dacsp-m5fy91">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63692362"/>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OMA" id="MESGAPW"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140980" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="23"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="510" mass="54796" checksum="A1E2F15F40BF062A" modified="2013-05-29" version="1">MMLNFLLACLQASASAGAAVGGPQVALEYGTFLGWTNTSNGVELFLGLPYAAPPVGDKRLRHPAPVNSFQGVQDATRQKADCMQAPSALNPIPASLLEDFANISATTSSRPGVVQTANTSEGCLYVNLFRPEGTREGAKLPVLFWIYGGGGINGRISAYVLPGQNIVQTSVENGQPIIFVAVNYRMSIWGFLPGQEVIDAGVSNLGILDQRAALDWVQKYVAAFGGDPENVTVSGGSAGAICTFFQLLMYGGQNAPFKRAILKSGSLVPMAPSPAAYPQARFDKFVALVGCAEAVDKISCLRGVPNELLAESVGNTTFWWTIKDLVLYAPQVDGWTLPDTPQNLLRQGRFAKVPIIVGDVMDEGAGFEAFWCNVTDEEGFEGWMENLYVKGRLKRNSAAYPQDPAQGSPFGTGNLYQLTPQTKRMNAIFGDYLFVAARRFVLSQYTAQGLPAWSYLYGHSRTAWYGASHGSDIASLFGLLKDQVSRGMMTAYISFVTTGNPNACCSTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYA0</accession>
    <name>M5FYA0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_53063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628406.1">
        <property type="nucleotide sequence ID" value="XM_040775148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYA0"/>
    <dbReference type="STRING" id="1858805.M5FYA0"/>
    <dbReference type="GeneID" id="63690210"/>
    <dbReference type="HOGENOM" id="CLU_000315_2_8_1"/>
    <dbReference type="OMA" id="QSCNHPD"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF14">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="64"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="493"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="670" mass="74994" checksum="025EDBC16B3C7CA4" modified="2013-05-29" version="1">MGDVPEVQVTSQEAQKALQDLFQSSVGDAEIDGIDMERDAHVEGFRDTIKLMPHQVKGRMWMKSREEGKAKGGILADDMGLGKTIQTFTRIVDGKRTDKEKEEGYARGTLIICPVGLIKQWREELGKMTVGLKVIEHHGSGRTKGIVLERADVVITSYSVVSSEHGASEGGSDHSKTAKKPKAKAKTGLEDFIAEGSDEEDSDEFAQQVVKKKSKKKPACPLFEIDWLRIVLDEAQNIKNKSAKMSIGCCALNSKFKWCLTGTPIQNSVDDLYPLLKFLVVKPLNDWTQFRQHISQPVKAGKPACPMKRLQVILKVIMLRRTKTDMINGQPLLKLPPREVQVVQCEFDKDEREFYAALQERTTLTFNKFLKRGDVMKNYTSVLVLLLRIRQACGHPGLVSKDFSEEKDALDPKAGKDDKDEQEVTQQEEDELADLLGKMNVGDKPEMCPINLDSDDSDESVVAIPRNEAAFPKKSHKSNGLPKLPPSSAKIRKIVELLTDIADRSNREEKTIIFSQFTGMLDLLEPFLKHHGVKFSRIDGSLRPVEREQAINKIKNDKATTVILISFKAGGVGLNLVCCNNVILVDLWWNPALEDQAFDRAHRLGQTRAVNIYKLVIENTVEDRILIMQDKKREVATVALSGGKLSKNKLDLNDLIALFKPSNGRDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYY2</accession>
    <name>M5FYY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628601.1">
        <property type="nucleotide sequence ID" value="XM_040770151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYY2"/>
    <dbReference type="STRING" id="1858805.M5FYY2"/>
    <dbReference type="GeneID" id="63685213"/>
    <dbReference type="HOGENOM" id="CLU_415614_0_0_1"/>
    <dbReference type="OMA" id="PSICICA"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="671" mass="74058" checksum="C491168DA5F67936" modified="2013-05-29" version="1">MAPSSDAALGDLEGTPGRVITRSSGRVDEKGKDVDQVQTSRSGQKAEGGRKTRRQNLRAKNEVHNINVVGSNKQQYTDQMGIDETIGRLKMKVSKDWKVSQSEMRVIALDQTQQPNGPDDPHFPWPTGENEETLPNVTSIGAALRLTGIEGPDEHKYHFFVWTQETGTGPGEHTRKAEESAEGEEARRKRQRQDTVLRNVQRTLTLALRAPPPSTAATQSGMATASATSTIFDGRGGRIGMSVSIYSPIFANLLGELRSSTNNIPPADVCKLAEQLCADSSKNYSDEDARVAAVSPTMDALLGQTSAKTVTTQNTSSDRSYTTSVFSDASGQVETAVAEYKNVLGSGKAEPIFQGVSSARKYWAQKEREDVRRVSPHPVISIALAGPWMFVQLVVFAEVVIAETVPELCVPLLANAGQHSDHTRDLAKKFVPLRKAMQRLRDYYRNLPKPPPSDEISPYLPAWTSVELLDSDKREAHLTYHRRLLDDFRSPLFEADLRAVGSEVSQRCVVKFCSTWGTAAHRLLAEKGFAPRLYGVKELPDGTKMVVMEKLSGEPIFKLDKVPPDVENDLREAVKILGDRGLVHGDLRSSNIICTKETTRSLGKIIDFDWADKEGFARYPYDLNDISEIPWAPGVGRGELIQRSHDVHMLEVSLCGNRVVSHSQSILTRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZC0</accession>
    <name>M5FZC0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623750.1">
        <property type="nucleotide sequence ID" value="XM_040769367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZC0"/>
    <dbReference type="STRING" id="1858805.M5FZC0"/>
    <dbReference type="GeneID" id="63684429"/>
    <dbReference type="HOGENOM" id="CLU_068979_0_0_1"/>
    <dbReference type="OMA" id="MNETIFA"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="75"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="292" mass="32335" checksum="7C97A5373B07F620" modified="2013-05-29" version="1">MPPSSYPGDSDTDIQRPLIEKLGVFLVKFGNHYNYWMLDTETNTFDLTRGGSKDAITFPTSARGNSSITIAPERSALVIIDMQKMNPRAELGRAAVGPTLDMIDAFRSNGMKIAWVQWGITEYDLKHLVSPALIYRFSGNKKAEGTSLCSEMGFVQNGTIDAGKKLCRGSWNAQAYGPLYDSYLKGKEMGTDFYFDKNSLSGLSGAMTPLEMWLRDSGITTLFFGGVNTDQCVWGTMKDSSFKGYDTIMVTDICATTSPEFATQMVLHNMHGRGWITNTGMILPVLWQVKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZM3</accession>
    <name>M5FZM3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arad-like aldolase/epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628232.1">
        <property type="nucleotide sequence ID" value="XM_040772837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZM3"/>
    <dbReference type="STRING" id="1858805.M5FZM3"/>
    <dbReference type="GeneID" id="63687899"/>
    <dbReference type="HOGENOM" id="CLU_006033_1_2_1"/>
    <dbReference type="OMA" id="YYDEQLA"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="70"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="34222" checksum="AB6F8EEAACAC0111" modified="2013-05-29" version="1">MSLSPILRRWRPHTTPVLLRALTTPPHSGYSFPTSTDFSRSPFEHVSVGHSRITLPTFASKAEEEQYRKEHLAAVFRVLAREGLAEGIAGHCSVRSAIDPSKFYINPWSKSFFRMKASDLVLVDGDGQVVQDGTETQGRSVDASATGLHAPIYREAEDVCSIVHVHGPYSKAFSALGKPVEMINQDACAFHGCIIDVGFEGLVVDESEGTQIVSRMTPSTKIALLQNHGSLALGRTSPDEAAWWFLSFEKVCRAQLLVMSALKPGEKPILVNDEAREFTLREMGTAEMGWLGFAGYYEREEWEDGDFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZM9</accession>
    <name>M5FZM9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_85397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623860.1">
        <property type="nucleotide sequence ID" value="XM_040776732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZM9"/>
    <dbReference type="STRING" id="1858805.M5FZM9"/>
    <dbReference type="GeneID" id="63691794"/>
    <dbReference type="HOGENOM" id="CLU_008891_4_2_1"/>
    <dbReference type="OMA" id="WGLKYAV"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT96962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="548" mass="58875" checksum="9D72FAB944E20879" modified="2013-05-29" version="1">MALRVPKANNIQLFKEGYKQVSGIDEAVLRNIEAVSELSDTVRTSFGPNGRNKLIINHLSKLFVTSDAATILREIEVVHPAAKLLVMASQAQEAEMGDATNFVLIFAGELLKKAEHLLVMGLHPSEVIQGYELALAKALKELENLNAHTVPTPPTLDSLTIALRPAIASKQYGSEDTLSSLVAEAALIVMPSKPSNFNVDNVRVVKILGGNISSSRVVRGMVFGRETEGIIKNLEKAKVAVYTCGIDIAQTETKGTVLLKNADQLLNFSTGEEKHMEKILKEIADSGVKMIVAGAGVGELALHYLDRLNIAVLKVLSKFDLRRLCRVVGATPLARLGAPTSEEAGYVDVMETTEIGSDRVTVLRQEKGETTKTATIVLRGATTNLLDDLERAVDDGVNVIKALVKEGRMVPGAGATELELARRVEAYGAGLRGLNQHAVRRYATALEVVVNTLAENAGLQTSEVVSRLYALHADRGPSWGVDIEGENNGTVDATEAQIFDSLAAKAWAIRLATEAAVSVLRVDSIIMSKPAGGPKIPQQQGGQDWDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G071</accession>
    <name>M5G071_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PQ-loop-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_108094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628447.1">
        <property type="nucleotide sequence ID" value="XM_040768586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G071"/>
    <dbReference type="GeneID" id="63683648"/>
    <dbReference type="HOGENOM" id="CLU_033734_2_0_1"/>
    <dbReference type="OMA" id="MCLQVPG"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF11">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41184" checksum="2EA814EA05CEF955" modified="2013-05-29" version="1">MHLLISDEPVCKPVHNPSTLFLTCFLCFGVVISYLPQHWRIIAKQTSEGISPWYLLLGSTSAAAGMLNVVTLQWGVVRCCSVWTVGQCLENTIGIVQVTMVWAMFSLIVVLFLRYFPPSARHHHIRHPHSGREYTDEEQECEEEEAEIQELLVATAEWNEAKALCALVLIHLITSIFVTFLVLSSPQSQPSRQAELWADFCGISGSLLTCFQYAPQIWKTYKDRLVGALSITMMCLQCPGSALFVFSLAFREGTNWTSWLPYATVGIMKALLLIICLVWKARQARLGIDDFGNPLSPLVGSCTEPCGLGLESGNGGNGLVHGESGPPGLAQAEAEDRPAAEGQQTEGRAGETTPLIFRAGTQGKVVQTLSKRITSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G099</accession>
    <name>M5G099_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_107111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629071.1">
        <property type="nucleotide sequence ID" value="XM_040768411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G099"/>
    <dbReference type="STRING" id="1858805.M5G099"/>
    <dbReference type="GeneID" id="63683473"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_9_1"/>
    <dbReference type="OMA" id="MGFAREF"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034040">
        <property type="term" value="F:ATPase-coupled lipid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF646">
        <property type="entry name" value="HAEMOLYSIN SECRETION ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="43"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="33451" checksum="870943B602B9EDFF" modified="2013-05-29" version="1">MQSLEQHFDCIRILYSCTDIQNQVPDGDEEISDFPGDPAGLSLQFKNVTFKYPQSSKLALEGVSFTIEPGQLCVVVGRNGSGKSSIVKLISRLYDCTGGMILVENHPVQQFRLTAYRRLVSTLPQEFTFFPLTVAENIGLGDPEHAEDHDRILKAAESGGAIEFIERDLADGFRTRLKGPSAFHIHSGDDRFSQWANKEVQKHRATSLSGGQWQKLALSRTFMRSSDVYLFQRLRDLRGKKTMLFVTHRFGHLTRTADKIIVMEAGQVLEQGTHSDLLAKEGLYARMYNSQAMAFSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0M5</accession>
    <name>M5G0M5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624250.1">
        <property type="nucleotide sequence ID" value="XM_040774025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0M5"/>
    <dbReference type="GeneID" id="63689087"/>
    <dbReference type="HOGENOM" id="CLU_2196865_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11673" checksum="0C0EAFE9F89FF587" modified="2013-05-29" version="1">MLLSQPLCVHSTAREMSGSYPSDFIPRLQDGVPAIWPLHLNIFPRPGPVHPTFVFLHLPFLLDKLGGGSFMRISGKVIPAGCVDLPCTLIEAGDVVDAMVACGVCFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0N4</accession>
    <name>M5G0N4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624260.1">
        <property type="nucleotide sequence ID" value="XM_040774027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0N4"/>
    <dbReference type="GeneID" id="63689089"/>
    <dbReference type="HOGENOM" id="CLU_2849646_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="65" mass="7343" checksum="F0DEF554B03753BE" modified="2013-05-29" version="1">MRCTALRARRDSGEYSRPYLVKFPLLAPRWSRRASSSSHGPRNVHSLDASHGSDLMHVAPDMYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G176</accession>
    <name>M5G176_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Solute symporter family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_18522</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624420.1">
        <property type="nucleotide sequence ID" value="XM_040771362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G176"/>
    <dbReference type="STRING" id="1858805.M5G176"/>
    <dbReference type="GeneID" id="63686424"/>
    <dbReference type="HOGENOM" id="CLU_010778_2_1_1"/>
    <dbReference type="OMA" id="WLDQAYW"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF2">
        <property type="entry name" value="SOLUTE SYMPORTER FAMILY TRANSPORTER (AFU_ORTHOLOGUE AFUA_6G03200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="611"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="533"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="635" mass="66805" checksum="BD3D4FD72556787B" modified="2013-05-29" version="1">MSTNDGIQVLSQGVGYGIVVGIGLFFALLMLGCTHLQNKYTSYSTHQAEEFSTASRNVEPGLIAAGIVSSWTWSATLLTSSTFAYTYGICGPMWYGAMGSFQILLFALIAIKIKSNAPGAHTFPEIILARHGRVAHITYLFNGLATNMLVGACLVLGGSQVVAALSGMNVYAACFLIPLVVAAYVIVGGLRSTFIADYTHTVILFIAIFIFGFEMYATNAVVGSIDRFYDLLVEASATMPIAGNYEGSYLTFKSVNGLVFAIDLLVAGFSTVWLDQAYWQRAIPSQPETSIKAYLLGGIAWYGIPFGFATAMGLGCAALTSTTSFPTYPNPLSAAQNGAGLSSQAAAIALLGKGGAGLMLLLLFMAVTSSTSAELIAVSSLLTFDVYKTYLRPHATSQQLVRISHYGIIIYAVVLAAFCSILSAVNINLTWLLTVLGVIVGGASVPVGLILLWDRMSTLSPIASPWSGLSFGLIAWLVTTMKRSGYIHVTTTGDATNAAAGNIASCAGGAVVATLLTLMFPAKHQSDDPIDIARSNKINGLSSPKKSPSGSNIPPSPDVPQNSDEAEKGPAVIVSAAPIEYVPTGNEMVDYLETSHIQPLDPVIAKKGERLALAANGLYAAIAIIVVPFTLFGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G177</accession>
    <name>M5G177_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630885.1">
        <property type="nucleotide sequence ID" value="XM_040768027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G177"/>
    <dbReference type="GeneID" id="63683089"/>
    <dbReference type="HOGENOM" id="CLU_2061406_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="12213" checksum="08E3B1500F804AC5" modified="2013-05-29" version="1">MDVNPIEEAPAAALMTSAVAKVPTIARVPPVVKASALALGKCPAMEELPSAHLQKMQSLMTATSSSCVSAIGKMYSAVVASLSGKSSSQKDEMAYTLPLQFAPMGIVITGGKCLPHPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1F1</accession>
    <name>M5G1F1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">DACRYDRAFT_79718</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628922.1">
        <property type="nucleotide sequence ID" value="XM_040776412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1F1"/>
    <dbReference type="STRING" id="1858805.M5G1F1"/>
    <dbReference type="GeneID" id="63691474"/>
    <dbReference type="HOGENOM" id="CLU_020376_0_0_1"/>
    <dbReference type="OMA" id="IWAPFTH"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067380" description="Lysosomal dipeptide transporter MFSD1" evidence="20">
        <location>
            <begin position="21"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EJU02025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="529" mass="57405" checksum="C621488FE1F7F888" modified="2013-05-29" version="1">MIRALALLCACALSVGSHYAQYFLGPIKSRLSREMGTSNAQFSLLIASFSLNNTWTPLLGGLLTARLGTAWSSVLATSLIFVGQLILLLGDTLESVRLMSLGFFVFGLGISPLAVVQETIIVRFFSSHGLGISLALGLLAGKGASFVSAITSFPLSERFGPRAPFVVATLLAGFSFAVNLLYLSYSAWFARSTGVGLEEGEARAAARKAQAASETGLSAAERMSEAEALRRIERKRRVRFRNIGKLGDVFWAYVGINVLCGAIWAPFMHLSANIIERRYGLTEADAGSRASLLMAGSIFLYPICGYLTDRLKTATVVHKMFVLSSILTLVCYSWLALPPEWTKSPTPALVAFSGGHGFATLLLVIIVPHLVPIKYVSSALGVHKALEQTGSTISQTLAGLLLDKTRSSTLDTPNNLQAISLLLRAFLAVNVVQLVSILGMWRLQDEERPAQQEALHTRTFSASSARPLLSKPSHHVLPHGNRKHMMAHSRVEKRRGAIFILLSGLAIVAAWVLFMVVAWEKLQDRVAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1K9</accession>
    <name>M5G1K9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_66151</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628997.1">
        <property type="nucleotide sequence ID" value="XM_040775805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1K9"/>
    <dbReference type="STRING" id="1858805.M5G1K9"/>
    <dbReference type="GeneID" id="63690867"/>
    <dbReference type="HOGENOM" id="CLU_023861_5_1_1"/>
    <dbReference type="OMA" id="NEMPSIC"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="308"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="439" mass="49439" checksum="9F221078337C2476" modified="2013-05-29" version="1">MSLYTITPALWQSITHYATFPQTGVSLQQMILFGEKHSQGTLLQAAQFLSEELPVRLAHRVKELEALPEGLSEMPSIVKVKNWYAQSFEELINFPPPQLTPELRKLLSKPTSPFPSATVNPALSSFSWSPPHAHHSAHPGSHANGTTDPHKRRIPIERRLYSSPPENVTWPPSVIDYNRRFTKTLEVIKRRHDPTATTVAAGVLEWKKRKKWGGVVLHEEIGKWLDRFYLSRIGIRFLIGQHIALNTQPVTPDHVGIICKHANVHSIVSEAIENARFICEEHYGLFKGPVVELICDEELTFPYVPGHLNHICFELLKNSLRATIERHGPSSPPPIKIIVSSGLEDITIKISDEGGGIPRSAVPWIWTYMYTTMENQALDEDFGESDFRAPMAGFGYGLPLSRLYARYFGGDLQLISLEGYGTDVYIHLNKLSSSEEPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X6</accession>
    <name>M5G1X6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_99740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629588.1">
        <property type="nucleotide sequence ID" value="XM_040777619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1X6"/>
    <dbReference type="STRING" id="1858805.M5G1X6"/>
    <dbReference type="GeneID" id="63692681"/>
    <dbReference type="HOGENOM" id="CLU_017968_2_0_1"/>
    <dbReference type="OMA" id="WETWPSS"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="630"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="645" mass="71240" checksum="204E90B02A29FF28" modified="2013-05-29" version="1">MSTRYKSTRSEGEWTTTSTNPGDGGGASSRRITSTYTDLLTISRPFLPTSSVKLLWMETVAEETSSGRTSPVMHTLVDLPPSLIDLISASDPTPAAQSYLSYISSLDLPTLLQEPSQLTTESATITSELTGLCQREYRTFLSVHQTTTSLSSSLGSLSSSLTSLLDELPALDTQCRAFADQTKILQASRQRATLVLEQSDKLLDILEIPQLLDTCVRNGHYQEALDLSAHATSLLKRFPSVQVVRDVAAEVDATMRQMLIQLLHVLREPAKLPNLFKAINFLRRMQPAPLTEPELALAFLTSRMSMLSASLHALEPERSVDPARYVRKYVDAFREGAYDILTQYTTIFLDRPSANKTPELQDYLTSFSHHLLSTLIGTLETALPLVEDASALSSLLTQLSYCSASFARIGLDFRALLAPLFEQAVLSATQRSLHRADSTLSTSLTAAGKSARPPSTFLLAFDAPESLFNTHTHAHTFTPQNPPAYLASLPPLATYLNSQLTTLNSLRLLAPSALLSPLLEALDASLCASSTALLTFCRSAWGTVTRRTSFEIDDSEREKQRERDKKVLLLVGRAWVDALGPFLRTGLVKGVYGREEAEESESWTRAKEEWDTWWDEIGERRRASINGVVEEERSPHESYDTKGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G288</accession>
    <name>M5G288_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_51785</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629224.1">
        <property type="nucleotide sequence ID" value="XM_040775058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G288"/>
    <dbReference type="GeneID" id="63690120"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067452" evidence="11">
        <location>
            <begin position="18"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="5"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="507" mass="55408" checksum="AC2EBA7D6ED41323" modified="2013-05-29" version="1">MLWFLSSIAIINSMVNGYDGSMMTGMQSLTQWNDSFNHPTSAALGLLNAIFNAGGTCGVVIAPYCTDLLGRRLGIAIGSVIILVGVILQAAAANTSMFIGARFIIGFGLSISSNAAPILVAELAHPRFRGTITSLYNTQWPLGGILAAWITYGTFQIPGAAAWRIPSALQAVPSVILLCFLPFMPESPRWLVDKGKSDQARAILGRLHGNGDIHAPLVELEMNEIEEAIKFERQNEKVSWLELIATPGNRYRMFLAICVGIFSQWSGNGLTGYYLTQILKQIGITDAQFQLRLNGGKEIQAWVLACVGAFLTDHVPRRVQFITGTSGMMICFSALTGLTAAYNNNPSRPIGLAAISFIFFYSAFYSCGWQGLTTLYPTEIMPYNIRAKGLAVSNLTVNLALFFNSYINPIGMANLGWKFYLVYVAWLPCEVLIMVFFFKETKGHTLEELAVIFDGEKAEVAGNRLGFDPAQQEIADVNAELAKVEGHGTSTPDDMEKGEPEHIERQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2C8</accession>
    <name>M5G2C8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tim17-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_48281</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631255.1">
        <property type="nucleotide sequence ID" value="XM_040774819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2C8"/>
    <dbReference type="STRING" id="1858805.M5G2C8"/>
    <dbReference type="GeneID" id="63689881"/>
    <dbReference type="HOGENOM" id="CLU_087811_3_0_1"/>
    <dbReference type="OMA" id="FDCTFQY"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="185" mass="19536" checksum="55ECDCBE41A221D2" modified="2013-05-29" version="1">MSHADHTRDPCPWVVLNDFGGAFAMGAVGGGIWHGIKGARNSPRGERLIGSIAAIKARAPVTGGNFGVWGGMFSTFDCAVKGYRKKEDAWNAIISGFLTGGCLAVRSGPRVMFQSAVACGILLGVFEGVGVLLNRMFSEQNRQQLPQSASPLPIHILVDREPILAPVMEPPPPQPVLSGPTHVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G345</accession>
    <name>M5G345_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631535.1">
        <property type="nucleotide sequence ID" value="XM_040771880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G345"/>
    <dbReference type="STRING" id="1858805.M5G345"/>
    <dbReference type="GeneID" id="63686942"/>
    <dbReference type="HOGENOM" id="CLU_973246_0_0_1"/>
    <dbReference type="OrthoDB" id="2576311at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="286" mass="29120" checksum="AA18E078610C570B" modified="2013-05-29" version="1">MTDLRHSGSPNPVSPQSNPNFILSHLPAWASGCPSYNPTSIPSSVEASSIHIPSWAFLPDNGSSWNPQSAQAVATGAVTPTSLPTGAPSASTAPGATSSVQGGVIAGAAGGGVVLLLLLVLAAYYLLRRYRQAEPRSPIDLSDTPAPPDPSPYFLTALPRAPSRLGIYKPPLGGWGHAYQPVSTGWELTPSGSSSGPSVERGDGLGAPRSAPLLPPTPSSGHSGFSGASGTSTPNATTGHSPVREEVRTPALPTYEQVSAEGSRSGGATPLLRPSGDRKRPQSAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G385</accession>
    <name>M5G385_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627234.1">
        <property type="nucleotide sequence ID" value="XM_040768804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G385"/>
    <dbReference type="GeneID" id="63683866"/>
    <dbReference type="HOGENOM" id="CLU_1107089_0_0_1"/>
    <dbReference type="OrthoDB" id="3395039at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="28846" checksum="2F55E62BE779C9A0" modified="2013-05-29" version="1">MVNFKEEHRRWLLERLPAFGAHADKRQGKKYASSIATAFRAHFPDYAPKRDVDSVDQQIYIFLKNSRAHAVDFLQKLSVAHEKHAPLINQARELMVTDIPNFADRLAEHAVNTNKPVFQARPEFLKSYWENELSEERRREYQESAERRREQVKQSNAAVQGTRGAPDTIFNTIATVQQALQARSGWVFLTLAGGLDMSGARTATLIDTGRTPSGLRFSEFHLRYDTEIHRTWVDFVKTAGPHFMSNTLLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D9</accession>
    <name>M5G3D9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627289.1">
        <property type="nucleotide sequence ID" value="XM_040773188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D9"/>
    <dbReference type="GeneID" id="63688250"/>
    <dbReference type="HOGENOM" id="CLU_2346641_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="97" mass="10504" checksum="8B71E5F90FFDFCEE" modified="2013-05-29" version="1">MNASRGSEADRYGEFILSGQSAAKIAEVEPENRGTELRTMSPPISGYPLWTKCVGDWMVRATTQGTAELLDLRRHGEDQAAMGKTTALSHFAPSCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3G0</accession>
    <name>M5G3G0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631650.1">
        <property type="nucleotide sequence ID" value="XM_040769755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3G0"/>
    <dbReference type="STRING" id="1858805.M5G3G0"/>
    <dbReference type="GeneID" id="63684817"/>
    <dbReference type="HOGENOM" id="CLU_1427927_0_0_1"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21662" checksum="1C18B150C2B00751" modified="2013-05-29" version="1">MSNSNEVKRIQDEHPGEACIIEDQILGKTLVTRTLGDWDQKWPKGMVGRLYPFLPFVSNKVPLIRKRLLTNSISPPYQTARADVTHEKLSGGRVIVIVASDGLPDNSARLTLDQHPDVEKRKQDMIQSWVRSASRKPLEGLEAERIMRDVLGGTDERKVLMNITDWFQLSIWDDLTLIVIDLSFPEERSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3L2</accession>
    <name>M5G3L2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625245.1">
        <property type="nucleotide sequence ID" value="XM_040769124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3L2"/>
    <dbReference type="STRING" id="1858805.M5G3L2"/>
    <dbReference type="GeneID" id="63684186"/>
    <dbReference type="HOGENOM" id="CLU_150609_0_0_1"/>
    <dbReference type="OMA" id="RWRYSLM"/>
    <dbReference type="OrthoDB" id="2131339at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021487">
        <property type="entry name" value="DUF3140"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630">
        <property type="entry name" value="POSSIBLE DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11338">
        <property type="entry name" value="DUF3140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13920" checksum="61DD10F8493B46A4" modified="2013-05-29" version="1">MKSEQEVIAEFNQYVNMSASELEEWLHTESATGAGWRADESGETVGHESGRKIVDILKRNPSKTVEKYTEDDIAHMRKVVSYCKRHLAQEEKLKESKSAQELADTKSTRSLKNWGHDPLKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3S1</accession>
    <name>M5G3S1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_101894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625305.1">
        <property type="nucleotide sequence ID" value="XM_040767594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3S1"/>
    <dbReference type="STRING" id="1858805.M5G3S1"/>
    <dbReference type="GeneID" id="63682656"/>
    <dbReference type="HOGENOM" id="CLU_035117_6_1_1"/>
    <dbReference type="OMA" id="MGKKVWH"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="8">
        <location>
            <begin position="78"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="9">
        <location>
            <begin position="212"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="361" mass="38238" checksum="9F81E301E7EFE417" modified="2013-05-29" version="1">MHPSVRCLSATISHSRNGPLTLGFIGLGAMGRHMAWNLYLKTLLAQQGPPPSQEPEPIMLLCDANEDGAKKFMNDCMEAKATENVLGGRMEFMESPRALAERANVIFTALPSSPEVKSVYLGEKGILAGLNREKDQLCVDATTLDVSVARDVSNTVREAGAEMVDAPMSGGIVGAKAGTLSFMVGGTEAAFNLAEPYLSKMGSRVIHCGASGMGLAAKISNNLVLGINQIAIAEGLLLGTSLGLEPALLTDIINRSTGRSWPSTVNNPIPGALKPPASPPCERGYEGGFASKLMLKDMSLAIHAAEDTGVPLPLGSKATDEYSNVVQDNELARKDFSVVYEYLRQRMTASRAGTSEKADLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Y9</accession>
    <name>M5G3Y9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625375.1">
        <property type="nucleotide sequence ID" value="XM_040773709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Y9"/>
    <dbReference type="STRING" id="1858805.M5G3Y9"/>
    <dbReference type="GeneID" id="63688771"/>
    <dbReference type="HOGENOM" id="CLU_1427935_0_0_1"/>
    <dbReference type="OrthoDB" id="19439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21364" checksum="855FFA76F1F8D79D" modified="2013-05-29" version="1">MVLPPVFLCPRVFVRPTTCPLRALSPTFRALSTAPSPSADQPTPPPILSGDSGRPTAPKPTEPPISIEHHDALPSSLADSEAPRVKKYDSAKYKAKDEHRGVNYGYYIMRTARGGEPVYEDIVRNGRKRTLIRLVKGDSKKLQQDLMETLFKPLGVTEETLLSRVRMPGHVEFRGHWRPHVVGWMRERGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G409</accession>
    <name>M5G409_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maf/Ham1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631890.1">
        <property type="nucleotide sequence ID" value="XM_040771984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G409"/>
    <dbReference type="STRING" id="1858805.M5G409"/>
    <dbReference type="GeneID" id="63687046"/>
    <dbReference type="HOGENOM" id="CLU_040416_0_2_1"/>
    <dbReference type="OMA" id="VIGCDSV"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="27197" checksum="C324DC05AB3617C0" modified="2013-05-29" version="1">MPHHNPVLDHALRTPAFIKLAGKRVVLASNSPRRREILRVVGLEPEVVPSTFAENLSQRDFESPYEYPVATATHKAVEVYERLVKEDPEDPPDLVIAADTVVLSSVTMPVPGTSASLINEPIPEILEKPSSQADNLRMLLDLNGQRCEVVTGITIVYPVLAAPGYAIQSIDERSFVYFADSPVHLLEAYADCREGIDRAGGFAVQGRGGLLISRVEGDYNNVVGFPVTSFFHWLEELIEEDEDFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4B3</accession>
    <name>M5G4B3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_47885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631995.1">
        <property type="nucleotide sequence ID" value="XM_040774789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4B3"/>
    <dbReference type="STRING" id="1858805.M5G4B3"/>
    <dbReference type="GeneID" id="63689851"/>
    <dbReference type="HOGENOM" id="CLU_1754037_0_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="16378" checksum="5FF467E5FA24B0C9" modified="2013-05-29" version="1" fragment="single">HQSVYAGIHPSKFRDSYKGKVVFITGASRGIGKATAYAFAECGASLFLVSRNQATIDKTVKEVETRFPGTHVGTALADVVRHEQVGEAFRKCIELFGKVDVVISNSGAMEVLGISEFYRSISMLKQARTDVLLQRWRTKIQMCGATFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4E6</accession>
    <name>M5G4E6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629999.1">
        <property type="nucleotide sequence ID" value="XM_040769988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4E6"/>
    <dbReference type="STRING" id="1858805.M5G4E6"/>
    <dbReference type="GeneID" id="63685050"/>
    <dbReference type="HOGENOM" id="CLU_395341_0_0_1"/>
    <dbReference type="OrthoDB" id="10531557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="697" mass="73722" checksum="0C53056E19202A7A" modified="2013-05-29" version="1">MSSTPRGSKRPLDDPERPPASPARRRGNSSNSSSSSGSTTVPDPAGAGSGLGSTGNARAQGNGPGMTGIGMGMPMGGMGGVGQQALGELGQALRTSTASPVTLAQLQQQFTRNSLSAQALPIGLGMGTGTGTGMGMGMTDVPLWQPWFGSAGPALQQAFPLPLPISLPPAPQGQPQPQGQQAQIPSGHGSPVAFGSLGLKNVPSSFGPPFQAQGISFPQLQPQNQNQQHQKQQNQNQAQNLSPAQTLQPQLTTSAGGDALLMPPPSLPLPARNSPTVPPGQFTFPPATGWAGGGHDALYRLFQSQSQSQSQSQSQSQSQAPLQPQQPGQFLSTSAPPTMSPSTPLLPLSSPGPKVQSVDPSPRVKPGSTLPSSQVSSLGDGDERMSDDEASGAGATVPSGANVVSTGSAPPLKGKRGEGSVWRPEETEDLFRWVFSSPQHILEADQRPSRFFIHTPASIGAPRPRHGIANRWKRLLETQRRLNEYDAWARAAGLEPYVDNKFRVGRQMDRAREEGVNLGQLTSFTAMIWYNRGWLKEFNQFIPPDRNEFPPAGTLTPASQNGPALAEEQASDDEDDDDEASEMMDAPTISSPFRRAPPLQAQVSPRPGMNLTSRRSAGNLLAPNAPTVQLNSPQSSSSRTLDDMPTDPAERKKSDKMDRAINVALQLVTQDSQNIDPALRKKATELLNSVLDQANDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Z8</accession>
    <name>M5G4Z8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630194.1">
        <property type="nucleotide sequence ID" value="XM_040772429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Z8"/>
    <dbReference type="GeneID" id="63687491"/>
    <dbReference type="HOGENOM" id="CLU_1245306_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="222" mass="23490" checksum="843FA956601FCE41" modified="2013-05-29" version="1">MGFIKADLMDQATTSQAVCQGTKHKRDCLELAYSKKVDQAFVEWEKKELNIGTNATPSSFLSLLASTNASSSSPANKEFGMPTPSSSTTMCHGHAESASLVVLGPPRMPMPLGLPFSPTVPPSTQPMSTLMATLTVSSPLHIFDAAGTSHMVHTIGCGKVLTPAPTKSFSRLATPTCTTCPTTPMPPVRTSSMVLEKNVLVKLNTTCMSCTSSIILVLGWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G573</accession>
    <name>M5G573_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RhoGAP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627879.1">
        <property type="nucleotide sequence ID" value="XM_040772963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G573"/>
    <dbReference type="STRING" id="1858805.M5G573"/>
    <dbReference type="GeneID" id="63688025"/>
    <dbReference type="HOGENOM" id="CLU_008682_1_1_1"/>
    <dbReference type="OMA" id="GECRDLI"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="1"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="385"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="579"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="669"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="585"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="694"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="709"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="727"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="745"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="759"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="782" mass="86354" checksum="EFB019957427E401" modified="2013-05-29" version="1">MSNDLSQPGPVPWFDHHLKVLNDSYIAFFQERAKLEENYVEALFKLCQRAKNVDSQLDRIETSSTRLAWREVTGELEREATTRGAFIESIRQDVLAPLSAFKETQERTRKRIKEDSKESYQRYQEMAESTLPRLKRNYIKKCQDVEDHRAQERAIEMQKQLLSNPLAAPTGPGGSLSNVPMAPQAISPIPLPPSAGLPTQRARSPSGSGGFSDLAQHGKKQFGQFMNFLNERRDVREGNGPVNKDMQILPIAERGSGPMRSVKAKREAEEADKEYRKGVFRLETLRLRREKILLAGYTSLEEFVKESAEVVKGVLRTYADGLEATGTANASLSRDLQHSVGSITPAKDASLVRAAVPNAMARALPKRVLYWNYSVGECNDLMFGVSLVDYATARSLADGEAPDLIMKCIEEVEERGLDSEGIYRVSGRHATVQELMRKIERNEDEFRFNPLLDDIYTICSLLKLYLRELPEPVFRFSLPDRLQYSDKREEHVSNNFLVLKSKLRRLPSIHQATLRVIVEHLAKVAGRSSQNKMDAKNLSLIFGPVVFGEDDMPKNGDVLSVGTTKDTLMEDLITFAPLVFSDQPAPSPTRPQSPPLPSKPENEEPAAGPRGNPYGTEHSSFVLIPPREKDAPTIPTQSGMTSSIHPSNRIQNSPTDALWTQGEHTVGIVTTESPPHLSSEPTASDEDRTVLAHSLSSSDSVGSTRSALTPSPSKSQRSSSKSQRTSPLNVTTALVPQSVHQDCETVSPTSTTPVTGGSFQSTKTSFSIEASASPGTDSGVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5E0</accession>
    <name>M5G5E0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine monophosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_77701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630793.1">
        <property type="nucleotide sequence ID" value="XM_040776285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5E0"/>
    <dbReference type="STRING" id="1858805.M5G5E0"/>
    <dbReference type="GeneID" id="63691347"/>
    <dbReference type="HOGENOM" id="CLU_038732_9_1_1"/>
    <dbReference type="OMA" id="FGWPEEY"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="34885" checksum="8DA50DC15E1D2263" modified="2013-05-29" version="1">MTFVSGGLLAAEVTRAGGFGFLAIEFRFGIERFQADFALARERLGTPEGEVLPIGVGVIGWMLDAPIGVKEMLKWAIMQGVKAVWLSFGEDIGKWVQFVREADEERGDGRKTLVAVQLGTVQQMKVAAEEWKVDIIVAQGSEAGGHSWAAASSTATLLTQVQAALPAPRPIILAAGGVSSGAHIASYLALGASGVVVGTLFAGTEESVYDPFSKDVILKAGYDDAVRTTLWDRVQTYPWPKGIDGRAICQQLRDDDAAGLGIDQIREKIKEDAKEGNRSREIVWAGYPAAYIKQIRPAKDVVEQLHRETVECLRLGTTLVKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5H0</accession>
    <name>M5G5H0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="1">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_40387</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625900.1">
        <property type="nucleotide sequence ID" value="XM_040774479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5H0"/>
    <dbReference type="STRING" id="1858805.M5G5H0"/>
    <dbReference type="GeneID" id="63689541"/>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_1"/>
    <dbReference type="OMA" id="HAIAHRK"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="17602" checksum="7526EA0673C65198" modified="2013-05-29" version="1" fragment="single">DLVGRHAMSFQLPTTSGEMFKFKPGGRPIALFFFPAAGTIGCVLQTCSIRDASNSKEIWSRAACEVIGISGNTIEENRHFVEDYRLPFTVLCDVDGAVRNMYRTGKGLLGYDAILPARVTFFIDSHGIIREIYDSFIHAIAHRKFIEKWIERIEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5V1</accession>
    <name>M5G5V1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_114509</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630993.1">
        <property type="nucleotide sequence ID" value="XM_040769834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5V1"/>
    <dbReference type="STRING" id="1858805.M5G5V1"/>
    <dbReference type="GeneID" id="63684896"/>
    <dbReference type="HOGENOM" id="CLU_016743_3_0_1"/>
    <dbReference type="OMA" id="IRTQMCW"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="12">
        <location>
            <begin position="384"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU04099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="488" mass="53935" checksum="88C379A715E243DD" modified="2013-05-29" version="1">MLFPSDGVISSKTPEFHAVILAGYGNNLDPLVDDEKGVHKALLPIGNQPMVSYALQWLEEARVFDVLFITPQSHKVAIQHHLSSQNSSWPSLRVELESVDDEEAESLGAADLLRMFADRIQSDAIVLPCDFVPPPSLPLNLLLNAHRVDVEDPVMTALLVETGEEVKDGPVPTLMGLHAQSNTLLFVDDNADPEDDVALRMNMLWRYPRVKMTNRLTDSHVYVFRRSVFDLLQQKDEISSVREQLVPFLCKLQYQPRRREKYGPIISPNANMQELALEHSTTYTPPPSQRNHASREKPIHKSVVSTPFTQSGASTPPGESVPASQAAEEPEGSPSDYPIRCNVVVHKDGYAARANTLGTYFELNRQCLRTTATAPVTGEGIDGKAQVSPDSLVGASTRIAERTTVKKCVIGKHCLIGKNVRISGSVLMDHVEVQDGAKIENCIISSNCRIGKNASLRDCQLQTGWVVDDEASHKGERLKRFEAYGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G657</accession>
    <name>M5G657_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632635.1">
        <property type="nucleotide sequence ID" value="XM_040771809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G657"/>
    <dbReference type="STRING" id="1858805.M5G657"/>
    <dbReference type="GeneID" id="63686871"/>
    <dbReference type="HOGENOM" id="CLU_042569_3_1_1"/>
    <dbReference type="OMA" id="FRICGMK"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF108">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38797" checksum="75E0022F7658576E" modified="2013-05-29" version="1">MEISTSDVPAAEQAGKETPSPTDSSVSLSVPFQVAGHTNTVETTADGSFVIKSSLPGERAFYETLACTLELSALRQWVPEFYGILRLEGVMRSQGKLDPPPADLGPAGKESLLLENMCQYVIKTNVMDVKLGRVLYAEDASAQKRAKMEKKARTSTTGETGIRLTGFHVYNRISDTQETYPRAYGYSLTAPRLIEGINAFFPCATSPDEIGHPPELLATILEGIEDDVEELIEVLEKLELRIVGTSLLVVYEGEGETLREVLKRQEVLQVAAEEGEGNEEEEDGEEEMEDEELEETPKLPWVVRLIDFAHSHLAPGRGPDEGAIFGLRTFLRLVRERREAVEKLMEIPSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6B9</accession>
    <name>M5G6B9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_98952</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631128.1">
        <property type="nucleotide sequence ID" value="XM_040777555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6B9"/>
    <dbReference type="STRING" id="1858805.M5G6B9"/>
    <dbReference type="GeneID" id="63692617"/>
    <dbReference type="HOGENOM" id="CLU_010194_15_2_1"/>
    <dbReference type="OMA" id="AYLYCMK"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057571">
        <property type="entry name" value="SDR_PhqE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23441">
        <property type="entry name" value="SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="259" mass="27428" checksum="2990086E6560E663" modified="2013-05-29" version="1">MSIATAQSAPSLRHLVDKLVVLVGGTSGIGYSVAQASLEHGARVIISSSTQAKVDAAVKRLLAVNPLFEGKVSGSTLNAKDVKSVEAFWDKVGKFDHLVWTAGDSLLTNFMDEDLETQKATFDVRFWGPVLSAKYAYKKGLFNPGASVTMSVGTVVRKPAKGWAMIAAVTGAVESITRGLAVELAPIRVNTVAPGGVDTELWGHMPADVKAGFMKGFADHSLVQHTATPDEIAESYLFLMKCTNMTGKTIDVEGGALLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6H6</accession>
    <name>M5G6H6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_105962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630704.1">
        <property type="nucleotide sequence ID" value="XM_040768177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6H6"/>
    <dbReference type="STRING" id="1858805.M5G6H6"/>
    <dbReference type="GeneID" id="63683239"/>
    <dbReference type="HOGENOM" id="CLU_005825_1_1_1"/>
    <dbReference type="OMA" id="HDELNYG"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000013">
        <property type="entry name" value="pre-mRNA-processing protein 40A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="605"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="792" mass="92191" checksum="AB39607B512A244E" modified="2013-05-29" version="1">MSTLWTEHRNSEGRTYWYNNDSRQSVWEKPDALKTPFERALANTPWKEYVANGRKYWYNTENKQSKWDMPDELTQLVTEVENNIPSPARLEPKTNAAATGTFGSSVTTQHAIVGTTPTTFVPAQVPLSNGTATGSGALGFVPATRPSISLPISTTSSLPSRPNLPPDPVIPQGGFATSEEGEKAFMHLLRKAGVDATWTWDQTMRAIITDPLYKSLKSLAEKKAAWQKYVEDLKAKEADEKEARLQRLRPAFKSLLSGSNNVYYYTTFRSAEKIFLGNPTWSQVKLEAERRMLFEEYVGGLMEKQTAATREMRTRNISKVVALLKELDVNVTTRWRNAQAQVLASKQWAEDAELRQLAPLDMLLAFEDYSRVLERDYEEVHRKRQIERTRDERKAREEFRVLHHSTMILIQLKYVKELLDELQRSGLIKAKSKWKTVYPYLDADPRYLTLLGTPGSTPLELFWDVADELSVKLDTLVTPVERVLAEHAFVFDHKTSSAEFHRFISEVVSLAHMPQAEESEIYDHLRDRALRRYADEKRRAERRLRHLQDDLRYALKKLDPPLDLDSAFEDAVPRIADLEEYKVLADDEGRRGAFIKFVKRQKEKLREVSEDGGSATSRKRKDSQSNGRSRRDYDLEHDREQEKPSKTSHHDGERYNFRRQLRDHERDKRHDKDKERDADRERERPRNREDVDHEKGHRSRQREERRSSRRSGRDEGNERDREWDESHRGGNAASKREREGHQERDGRERGEWSHEKSHRELSEERPPKRPRVQDSPSQQSPIRAETPEEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Z1</accession>
    <name>M5G6Z1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628479.1">
        <property type="nucleotide sequence ID" value="XM_040772911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Z1"/>
    <dbReference type="GeneID" id="63687973"/>
    <dbReference type="HOGENOM" id="CLU_2677720_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="75" mass="8517" checksum="4FDB2EA463ACD502" modified="2013-05-29" version="1" fragment="single">MNRTHLSRDYNYCIPVSGAIPTGPHKAWDPSQKHPSPSYGELSIPASTWHMSIFLEQPYVDDTHRIHSEHPPPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G760</accession>
    <name>M5G760_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase signature enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_47707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631453.1">
        <property type="nucleotide sequence ID" value="XM_040774777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G760"/>
    <dbReference type="STRING" id="1858805.M5G760"/>
    <dbReference type="GeneID" id="63689839"/>
    <dbReference type="HOGENOM" id="CLU_009600_14_2_1"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF5">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067551" evidence="1">
        <location>
            <begin position="21"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="526" mass="55921" checksum="EC605A478D2C6C18" modified="2013-05-29" version="1">MFTLLILLLALSLRPSPSLGWSTFDPREATISSIRHALLYQNTSCLSIVRSFLARIDAYDQQGPALDSFIAVSPNAEDYASALDALLAQPGYSPGPMFCVPIVLKDNYNTFDQPTTGGCLALQGAQPKTDAPVVSRLREAGAIILGKANMNEFALTGLSDSSLGGQVRNPYDLTRTPGGSSGGTGAAVAASLAVWGTGSDTVNSIRSPASANSLVGLRPTRGLITREGIMPLGYTQDAIGPLARTVQDVALALDVMVGPSKGDNVSALGAPFVGKNYENALVGGALPGLRIGVVEALIGNNTSNETTLVTSVFNTVLTKLEQAGAVLVPITDPSLAQPTVFNNYDVENWEFRQELDDYLQSGMFDYLPYDSFEQIFDIGLWLPGNEAVPPWVAAQDPATYNTLSPAYLAKLAAIEQFRIQLAMTFENNDVSVLFYPHQQILPVLIAPNASQSGRNGILAAVAGYPAIGVPGGFSPPTSTAPIGIPVGVEFMGRPFGERQLLNIAYSFEQMNRARRAPLSTWDTVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7D3</accession>
    <name>M5G7D3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_19425</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633030.1">
        <property type="nucleotide sequence ID" value="XM_040771505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7D3"/>
    <dbReference type="STRING" id="1858805.M5G7D3"/>
    <dbReference type="GeneID" id="63686567"/>
    <dbReference type="HOGENOM" id="CLU_013175_0_0_1"/>
    <dbReference type="OMA" id="KVMKGML"/>
    <dbReference type="OrthoDB" id="1053771at2759"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03312">
        <property type="entry name" value="CIMS_N_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000002">
        <property type="entry name" value="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003556">
        <property type="entry name" value="PRK05222.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30519">
        <property type="entry name" value="5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE N-terminal" evidence="15">
        <location>
            <begin position="4"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="14">
        <location>
            <begin position="436"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="441"/>
            <end position="443"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="441"/>
            <end position="443"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="651"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="675"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="736"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU06136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="765" mass="84790" checksum="2FDC9A1385F755AB" modified="2013-05-29" version="1">MVLSSVLGFPRIGANREIKKAVEAYWGGKLPEAELLKVVAEVKKYNWTTIKAQGVDLIPSGEFTLYDHVLDHSVAFNAIPKRYQGHGLSLLDIFFAMGRGRQQGSVDVPACEMKKWFDSNYHFVVPEIFEGIDFKLNYNKALDEYKEAKAVGVTTRPVVLGPISYLALAKASREASAGYSPISALSKLLPVYEQLLSELKAAGVESVQIDEPVLVLDSAADLAQQYETAYAALSKVSPSIVLTTYFGRLGDNLSFVSKLPIAALHIDLDREPKQLAAVANAIKPTTLLLSLGLVSGRNIWKTDFAYASTLAEEAIAILGEQRVIVATSSSLLHTPVTLTNEKKLPLEQLDWFSFATEKAAEVATIAASVSKSTSPAVAAALAANKESIAKRRAFEKNSDDAVRKRVAAITPEMLNRQNPFSIRVKAQHEHLKLPKFPTTTIGSFPQTKEIRTARAKLGKKELTEAEYNEFIKKEIETVVRFQEKVGLDILVHGEPERNDMVQYFGEQLQGFVFTQNAWVQSYGSRYVRPPIICADVSRKGPMTVEWSSYAQSLTDKPMKGMLTGPVTILNWSFPRVDISREMQSKQLALALRDEVVDLEKAGISAIQVDEPAIREGLPLRRVDWDGYLKWAVDSFRLSTAGLTDKTQAHSHFCYSDFNDIFPSILALDADVISIEASKSDMKLLNAFKEFSYSNEIGPGVYDIHSPRVPSVEEIKERITGMLQLIPDNLLYINPDCGLKTRGWKETEAALANMVEAAKWARQTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7D7</accession>
    <name>M5G7D7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631538.1">
        <property type="nucleotide sequence ID" value="XM_040771881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7D7"/>
    <dbReference type="STRING" id="1858805.M5G7D7"/>
    <dbReference type="GeneID" id="63686943"/>
    <dbReference type="HOGENOM" id="CLU_070319_0_0_1"/>
    <dbReference type="OMA" id="YRMTVIS"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032633">
        <property type="entry name" value="ThiJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF22">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17124">
        <property type="entry name" value="ThiJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="27775" checksum="431FD9E480E5382A" modified="2013-05-29" version="1">METEAPAEPTGTILVVLSDASSPLERKDGDVVHEETATFVAELAKPLEQLLDAGYEVTFASPSGRKPSLSPLSNSLLSHLLAYYARKPTLSQLQKQRAESALASPRSFASVTDEEVDNFEGVFVPGGKTPMMELGEDAELGRLLWGFHNLGKPTAALYHGVYALLSTLHASEYSGFAYPGYRITTFSNPDEKSNAPNSGPLISNMEDALKAAGATLVSEKDQREMGEITHDRELVTAGNFTGAKTLAEEFLEMLTGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Y4</accession>
    <name>M5G7Y4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_117507</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626775.1">
        <property type="nucleotide sequence ID" value="XM_040770397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Y4"/>
    <dbReference type="STRING" id="1858805.M5G7Y4"/>
    <dbReference type="GeneID" id="63685459"/>
    <dbReference type="HOGENOM" id="CLU_014280_2_0_1"/>
    <dbReference type="OMA" id="FGQWTIT"/>
    <dbReference type="OrthoDB" id="63070at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051859">
        <property type="entry name" value="DCAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847:SF7">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="410"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="457"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="682" mass="75967" checksum="A9CA7A524FBE49E9" modified="2013-05-29" version="1">MELPDHATIANVWLDEIDVEGDEVDTRDEDMDDEEDVMEDDYDEDGDFDPDEEADLLAEEGLISESEIADIRADAETSRVLEEMATQAELTNASAESVVARSQALTAVIQRLMQARRGSIRVTNAGIPTLGVRTDGGNEEEDDDDDSAFLYSRWAPPKSAARFFQPLLQPVKAGLDLLSSGEFGSTDLSLRNLSGERASLARILRERELSNNPRTREELGRTYIPNSHGTIVGLYGANVYSGQFSADSSFFYTCSQDFMLHIYDTTAPPSGQIQRPSFPQQRYRRWGIDESEEHQTTMKTVKSMRGNPGSWTITDVDLSPDNERMIYSSITSTIYMARTRDPTDEEQIPLYFHDRIGRRLRTVGDDDGGFNIWSCRFSADGTEVVAGAGNKQDGILFVYDLNAQRRVLKITAHEDDINSCCWADTASGNVLISASDDTFVKVWDRRSLSGGKPSGVLVGHTEGITNVAPKGDGRYVISNGKDQGLRLWDLRKMRSSQEFEEMSRTHYGIPEWDYRSGVYRTPRYLAHPKDCSVMTFRGHTVLRTLIRCHFSPAATTGSSYVYSGSADGKIHIWSLDGRIVQVLDRAKALPISFDASSEAPPLTSRRSQSGVIVRDVSWHTSEPVLMSSAWAGSRMASSVARHEWKGFGRNGMTLEDVVEKEAMESTERTMPGAFTSAVRDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Y6</accession>
    <name>M5G7Y6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633215.1">
        <property type="nucleotide sequence ID" value="XM_040767734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Y6"/>
    <dbReference type="STRING" id="1858805.M5G7Y6"/>
    <dbReference type="GeneID" id="63682796"/>
    <dbReference type="HOGENOM" id="CLU_035247_0_0_1"/>
    <dbReference type="OMA" id="HRVWHRS"/>
    <dbReference type="OrthoDB" id="2532648at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="8"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="533" mass="58763" checksum="A42AA4CEAAC30598" modified="2013-05-29" version="1">MTALARPLCPLDLLPVELFASILSELDLASLLAASSVSTLFRSVVASPLLNPWRQPIRRVLLSSDPYPAEFALLGARQIVPRRNWIEILALARLEWILLSATMPSLTEKMWEEAFNRRWLPGMRRWKKEGSWQEAFKRTAMRLWHRLNTSCTADESWCRYVLLNRNGSANLCEAYARTFNPLAVFDEFKLQANLMHLETQVRLIVQFLDIRVIALGVLHHASSLFVNSNARQLLHPPGVQSWIDDSETISDGTEASDTLASMPLSIASQRSLQVAFTPQSLRNPYTPLLMQNVGIPLSRARSSGSTDDEPPNGRYRRRTMSNEPGTGILRRLTVSLGAGIFGVGQADAGPASPQSAGPVLGRSASHQPEHTRSQPPPPRHTNGHTHSFSASTSSPLQAESAGPSSSRTHTTTDDPISSSLAPPVGELTYPPLRYPTPISAHRNYPNYTPGGGDNRWRSKGTLLELDEGGKLWAGPMMIVAQLVHPDHAEVGEDLDLVGQTKWAAFTVQDLFAIAPWMEERITKVVDGMGLGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8B4</accession>
    <name>M5G8B4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferritin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633350.1">
        <property type="nucleotide sequence ID" value="XM_040769577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8B4"/>
    <dbReference type="STRING" id="1858805.M5G8B4"/>
    <dbReference type="GeneID" id="63684639"/>
    <dbReference type="HOGENOM" id="CLU_029630_1_0_1"/>
    <dbReference type="OMA" id="NGPVAIW"/>
    <dbReference type="OrthoDB" id="1001765at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067557" description="Ferritin-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="37371" checksum="0CFCA7D048BE0D03" modified="2013-05-29" version="1">MRFFQSATALLAASGAALAAPLNKAKRTASAADIQTLQFLHMMEEFEATYYLEGLSAFSAADFSAAGWAIPDLVLENLLTFATDQSNHIQFWGSVLESVGSQPISTCAFHFEPVLTDVATWLQFGREMEYIGMGALMSALTMLDSPEMLLDVTNIVTVEARHQTLFNIFNGAEAVTQSYDAALTPSQLLAMAGQFITGCEIFPMDLPMVPQVTHLFAGMPAGLALNWTWGNATTQTVNADAFWCQWTSGTATDAVVQPITQCVSPAINGYVFAWITNSSTPLTTDITTQNVNNVVAGPAIAFVDSQKDILSELAVTGTADVNDINTISSAQAAALMGSSNGTMTTASGTVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F0</accession>
    <name>M5G8F0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631928.1">
        <property type="nucleotide sequence ID" value="XM_040767997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F0"/>
    <dbReference type="GeneID" id="63683059"/>
    <dbReference type="HOGENOM" id="CLU_1184970_0_0_1"/>
    <dbReference type="OrthoDB" id="3362915at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="22856" checksum="AE79182CEA950879" modified="2013-05-29" version="1">MTIPQLPDFQTMESWTPGTVWFFWCGFETAGSVPAVVQPVLSWGQDDPTGYVGYGGFSHYEWLLSLWDVPGTDGQEVFQSPALSISPGDELNFEVFFSGTQWRQTAKCVSGTCAGQNITLDVAYTDFAASPTANLLLCESELYGSLSNQWDFDVTWTAVTAIASNNQNVANACVQAGSVSDGNGYATVSNLQVSWDENQCRWDSITLSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Q9</accession>
    <name>M5G8Q9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633490.1">
        <property type="nucleotide sequence ID" value="XM_040771616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Q9"/>
    <dbReference type="GeneID" id="63686678"/>
    <dbReference type="HOGENOM" id="CLU_1224730_0_0_1"/>
    <dbReference type="OrthoDB" id="10393546at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="25571" checksum="6D3F5A461444B39A" modified="2013-05-29" version="1">MAIKSSSRLELPISQFCSLVSRCPQLRYIHVPFSLDFPRGLLPDARLVVPKLQYLFAEGLNCSDMASAKAYIPLNLPKLDRVLATGIDNKVQEVLDDLRITFNFPDADTLADLRLQLAGDEQPLRRQVLRSLFRRPKKRYLRAKPVRRELITIKQERTDETLFDDQPEDQVLEIRLTDLELPILVEPPPSPRTILSASDIPSAFRSSVSSLSEESPPSATSIYVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G986</accession>
    <name>M5G986_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627250.1">
        <property type="nucleotide sequence ID" value="XM_040768806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G986"/>
    <dbReference type="GeneID" id="63683868"/>
    <dbReference type="HOGENOM" id="CLU_2469035_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="9573" checksum="C43EAD676092D438" modified="2013-05-29" version="1">MRSTSPWFATRNSIALARAFTETLCDCQQRPHDINLATSKTWAVKAEVVKGMCQVSLIFACGTALFSDGYANGLVGALNLLLMTVYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9B7</accession>
    <name>M5G9B7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hemin import ATP-binding protein hmuV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629351.1">
        <property type="nucleotide sequence ID" value="XM_040772671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9B7"/>
    <dbReference type="STRING" id="1858805.M5G9B7"/>
    <dbReference type="GeneID" id="63687733"/>
    <dbReference type="HOGENOM" id="CLU_017344_3_0_1"/>
    <dbReference type="OMA" id="KCQQECK"/>
    <dbReference type="OrthoDB" id="6593433at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000144">
        <property type="entry name" value="ATP-binding cassette sub-family E member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="168"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="49265" checksum="BC6A7564E668F359" modified="2013-05-29" version="1">MKASATVSEMLDSKLEMGNKDEIVNVLELNEVLDRDISVLSGGELQRFAIAMSCVQNADVYMFDEPSSYLDIRQRLTAARTIRSLVRAQSYVIAVEHDLSVLDYLSDFICCLYGKPGVYGVVTMPYSVREGINIFLDGFIPTENLRFRDDALTFKMSETADEVLLDRTRRFQYPKMSKTLGNFKLDVQSGNFTNSEIIVILGENGTGKTTFVRMLAGALEPDDAKTSVKYNVSLKPQKIAPKFPGTVRMLLLKQIKAAFMHPQFNTDVVKPMNIENVIDQEVQTLSGGELQRVAIVLALGKPADIYLLDEPSSFLDSEQRITASKVVKRYILHSKKTAFVIEHDFIMATYLADRVVVLEGQPAIHATATPPQSLLTGMNQFLASLEITFRRDPTNFRPRVNKFDSIKDREQKSSGSYFFLEDAAEDQSRSTKTSAPGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA32</accession>
    <name>M5GA32_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="17">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_100760</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="17"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627605.1">
        <property type="nucleotide sequence ID" value="XM_040767486.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GA32"/>
    <dbReference type="GeneID" id="63682548"/>
    <dbReference type="HOGENOM" id="CLU_000846_1_1_1"/>
    <dbReference type="OMA" id="DMMIYQR"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF153">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1106"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1134"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1185"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1221"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1251"/>
            <end position="1272"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1292"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="75"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="20">
        <location>
            <begin position="1071"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="579"/>
            <end position="618"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1387"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1447"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
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            <begin position="579"/>
            <end position="591"/>
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    </feature>
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            <begin position="1398"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1503"/>
            <end position="1512"/>
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    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="14">
        <location>
            <position position="557"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="557"/>
        </location>
        <ligand>
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    <feature type="binding site" evidence="16">
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            <position position="557"/>
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        <ligand>
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    <feature type="binding site" evidence="15">
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            <position position="559"/>
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        <ligand>
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    <feature type="binding site" evidence="15">
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    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="744"/>
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        <ligand>
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    <feature type="binding site" evidence="15">
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    <feature type="binding site" evidence="15">
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    <feature type="binding site" evidence="15">
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    <feature type="binding site" evidence="15">
        <location>
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        <ligand>
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    <feature type="binding site" evidence="16">
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            <position position="1045"/>
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        <ligand>
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    <feature type="binding site" evidence="15">
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        <ligand>
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    <feature type="binding site" evidence="15">
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        <ligand>
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    <evidence type="ECO:0000256" key="2">
        <source>
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    <evidence type="ECO:0000256" key="3">
        <source>
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    <evidence type="ECO:0000256" key="4">
        <source>
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    <evidence type="ECO:0000256" key="5">
        <source>
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    <evidence type="ECO:0000256" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
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    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
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    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU00708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1518" mass="170873" checksum="617C8579304FAB06" modified="2013-05-29" version="1">MAYTKSSKRPPKHNKANQKPSFWSRLSSISAEHLIERLFEAKPRPSGPRTVYLNENLPQECYDSKHKGRVRHDCIYNTNQVVTSKYTVITFVPRNLLEQFRRVANLFFLGIDVLQFFPKFATISPGLVILPLIVVLAITGAKAGYEDLKRHQSDRKGNQSPTHVLTGGGYVNPNQMGRKARTYSIPLPWKKKKVIDEEKIAEDEKELRRVMSERSEHPEREIEMRERDVKVGVVRTSSSAAGGSRPHADSTGSTTLRASGDEFQPMDVDQDALSTASRNTPHFGRTVWEDIAVGSFIKIYNNESVPADIVICATSEPENVAFVETKNLDGETNLKSRRSVEGLTHLRTAHECALAQFRIEAEAPHVDMYKLNAAVVMYGEDGSMKHPVDAQMCLLRGTVLRNTEWVIGVVLYTGFDTKIMLNSGGTPSKRSKVERQMNPQVIVNLALLAIISVVCAIADSAIEKQKQPMGAYWLYDDNRSGDNPSINGLITFFQALITFQNVIPISLYLSIEFVWTCQAAFIYFDKEIWYDKTDTATLARSWNLSDDLGQIQYVMSDKTGTLTQNKMVFRQCSIGGKMYKGEPDETDEDRRAKAKATSLETSSQSSSDQSATKLLPEPAHRFVDPELETDLRHSGQNAHVQNLVGFFDVLGLCHTVLAGEDEHGKLQYKAQSPDEAALVQAAADVGFVFRGRDKEILRLQTPFSHELEQYELLNVLEFTSARKRMSVVIRRVDGEDHRLLLLSKGADNVIFERLAPGQTDIRSKTDEHLQFFAGLGLRTLCLAYRVLDENEYDAWSREYHEAETALEDRDDKLEEACSKLEQKMRLLGATAIEDKLQDGVPEAIADLKRAGIKVWVATGDKLETAISIGYSTNLLAKDANLVIVRGTGGDSDRTPVYDQLRGAAATFFSEERIEEKHPEVLSPDDYEVQMHGRPTFLRRLSSHHTEPRSPVARGSFDGTRLRRFNTGVSSLVGPDNGHKPGGYSLVIDGAGLAEALAENWSKALLMQVSTRCEAVVCCRVSPKQKAQIVHLVKDGLGAMCLAIGDGANDVSMIQAADVGVGISGEEGLQAVNSSDYAIAQFRFLTRLLFVHGHWSYIRNSNMILNFFYKNIVAIGVLFWFQIYCAWSTTYVFEYTYLLFWNVFWSLCPVIAIGIFDRNIDGDILVALPELYRYGREGRWFGTWRFTIYMLEAGYQSVVIFFFILYAYATTSARSDGWDVDMYEFSTTMVISCVMAVNLYNGINTYAWSGWVWFAVIIGPILCWLYTIVYNAIPPSSFFTFVYGNNYFLFPSAYYWFGLFQTLFLALLPRYVWKTINESYLPDDIDVLRQIRAFYPNIDVKSDPGLGGRFKAETLPEKEELEPHPEPENIYAEPEHATDLLRRSIDSSAAPETPRHNYPPTSDSIYRQRQATGSRTEMSTGRRGTGPGGGFDFSQEEGGFAIQRMQSHLSEMSERRRRERGSLASRLLHSTTPRRDRSGSGGSVGLFPSLRRSTRRRREIPSQQEPPVPSPPEPAHRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAF9</accession>
    <name>M5GAF9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_19874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632229.1">
        <property type="nucleotide sequence ID" value="XM_040771694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAF9"/>
    <dbReference type="STRING" id="1858805.M5GAF9"/>
    <dbReference type="GeneID" id="63686756"/>
    <dbReference type="HOGENOM" id="CLU_014401_1_1_1"/>
    <dbReference type="OMA" id="CNILQQV"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="590" mass="64698" checksum="D4E2328B2435389C" modified="2013-05-29" version="1">MSTEEPRMPKQQQREALHQFQEPRSLRFAQVVSAVIYCLFASGVIFGYAALKPVLVSEGVYRHLCTPDEIKSHVRVCREQELRMNVMFNIAAVTTNVAALPVGAILDRFGPQVTSLVGCVFLLFGPVLLAIAPMIPVDKFDGFILGYLLLALGGPCIFISTFQLSNAFPTNSGLVLSCVTGAFDASSAVWLAYRLLYQSTVDSEDQVGKGKISLTIFFACYCIVPVTITILQFTIMPKQSYKSMGEIVREIETGTLDPHEEAVDDDEINGLTPPPATARVLSSTSTSVDHEQDGHVRIVEPGPSEHTGLLSLSRKSNTADIRQRRRSSAVSQISAIIGQQAVERVQKKEEHKRAISGVWGSLHGESALRQVGSLWFILVVLFVMLQMLRTNYFIATVRPQYEHLLQSWELSLAIDRFFDLALPLGGLISIPFIGILLDHTSSPLALSVLVLFAAVIGCLGIIPHSLTAGYANVALFVVYRPFFYTSISDYAAKVFGFETFGIVYGLIICTSGLFNLVQSVLDYATIHVHQGNPIPVNIGLLISGLVIGSIFVAFVEDQVNRIKRSKAREALEEAENIQEVVVPDGSPAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAH9</accession>
    <name>M5GAH9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20202</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632743.1">
        <property type="nucleotide sequence ID" value="XM_040771848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAH9"/>
    <dbReference type="STRING" id="1858805.M5GAH9"/>
    <dbReference type="GeneID" id="63686910"/>
    <dbReference type="HOGENOM" id="CLU_010647_2_1_1"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000957">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3L, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="156"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="281" mass="30482" checksum="6CBA40E807C2F2AD" modified="2013-05-29" version="1" fragment="single">MHVGPTNSGKTHQALQALVRARTGVYAGPLRLLAHEIWKRVNTGQIDGLARTCNLLTGEEQRWVGERASHLACTVEMTPCGTELDVVVLDEIQLLADPDRGSSWMQVLLGANAQEVHVCGEDTAVGLVQRIAEECGDVVEVRRYERLTPLKMAKQSLNGDLTKIQPGDAIVAFNRNHIFQIAKQVTEKTGHATALAYGAMPPEVRNQQARIFNDPGSSLNVLVASDAIGMGLNLKIKRVIFHRMTKWNGTEVVELSPSQAKQIAGRAGRFGLHGAGEGGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAP1</accession>
    <name>M5GAP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_115310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629926.1">
        <property type="nucleotide sequence ID" value="XM_040769977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAP1"/>
    <dbReference type="STRING" id="1858805.M5GAP1"/>
    <dbReference type="GeneID" id="63685039"/>
    <dbReference type="HOGENOM" id="CLU_025894_2_0_1"/>
    <dbReference type="OMA" id="LGYGFMP"/>
    <dbReference type="OrthoDB" id="10027823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520:SF5">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="3">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="427" mass="46239" checksum="1A4FD41F3E5ED0DA" modified="2013-05-29" version="1">MFSTLGFSDSQIGIFMTLTLLGDVFISLLLTLVADKIGRRRILVAGALLMLISGVVFAISSSFSILLLAAIVGVISPSGNEIGPFRSVEESIQAQITPPHLRAEIFAISGIVDALSTALGQISIGFFTRYMKGKGWSELAGYRATFWLYAACAAVKLGLTLLMSEECEVEPVREYMPVSTDEDIPLSAKSSPQTEPPTPIALEDNPRGVWSTIVSSFPTFSEESKPIVLKLALLLGLGSGASGLVPMSIIVYFFSQTFHLPTNILGLIFFTTSLVSDIAQLLSATVAKRLGLIKTMFVTHLPSSLLLALIPIPNVYLASTVLVIRFCTGTMDVAPRTALISQLVLGEERTSVMGILNTVRTLTQAVGPWLSGWLSEGGRLWISFVVAAVLKSSYDFGLLAMFWNARPREEVVVQNNDDRHEQDEESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAR5</accession>
    <name>M5GAR5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_45114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632863.1">
        <property type="nucleotide sequence ID" value="XM_040774625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAR5"/>
    <dbReference type="STRING" id="1858805.M5GAR5"/>
    <dbReference type="GeneID" id="63689687"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="SWRLDRE"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="498" mass="55899" checksum="6FC6B6186158AFA9" modified="2013-05-29" version="1">MHIPDVTADNAVASALAEWMIVAYDAYMPTCSHTRIKLRGPPRPSWLYGYNKIFLTTPSAQLHETWQAKYGDAYSLPVAVGETRIALLDPKALVWVFSSNVYNYVRPVGQSKLVASLVWDDHKRIRKTMMPGFTPAALRSFTTVFLEEAYHVKDAWSTMFSEQKGGLDSIGKAGFGHDFASVTGEKPLIQKLLDSFGTSRQSPITALVLSLVHAFPILVDLPTKRKVFRDKLRMAMMGIATDILEESHKVGEEGRKSLIENVLSRSTSFPPIHHSWQINTIMFAGYDTTSTTLLWALHELSLNPTAQSKLREELSQFHEPTYDHLREKMVYLDAVVKEVLRLHPSIVEIYWNAIKDDVLPLARPITTASGEQISQIPIKGGQGITVPIEALVRSPAIWGEDSHEFRPERWNEHLPERVREFHAWSNLWTFGDGPRGCIGRTFAIAELKAVICILIQNFTFEPLTPGGKDVRRVPGVTPRPVNDGSHGLKLRVSQIGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB77</accession>
    <name>M5GB77_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pali-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_106446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630176.1">
        <property type="nucleotide sequence ID" value="XM_040768270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB77"/>
    <dbReference type="STRING" id="1858805.M5GB77"/>
    <dbReference type="GeneID" id="63683332"/>
    <dbReference type="HOGENOM" id="CLU_088627_0_0_1"/>
    <dbReference type="OMA" id="AFCIDIA"/>
    <dbReference type="OrthoDB" id="2354757at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF4">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="30210" checksum="DCA8299D6E22BFD2" modified="2013-05-29" version="1">MGDRDMNDHGMNARGVNNRETNDGEMNHEMNDSPADSIEQPIDTMATVLWIPGIIFLFLALLLSILVTISVPPIHRFDITRVHFFDGLGSITNQPPDFSGEFRFGLWGYCFTIDTSAGFHCVTTGNGYSVTFVNQARVSETVGSSWTRGLAVHVVACIVTAIAFVLSFSERATERLVCSVFSLFATLFTLAAYACDIALLGWVRHQTDQLNISQSTYPGQAFWMTLVILIVLILATVTSCLGYQTVRKEGGDGGHRRRVPWQRSEKTGKPPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBG7</accession>
    <name>M5GBG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_13005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633193.1">
        <property type="nucleotide sequence ID" value="XM_040770956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBG7"/>
    <dbReference type="STRING" id="1858805.M5GBG7"/>
    <dbReference type="GeneID" id="63686018"/>
    <dbReference type="HOGENOM" id="CLU_885731_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="35261" checksum="913971E9FBA8EA9C" modified="2013-05-29" version="1">MATPKKHTVHGEGRPKIAPNIPSKTSIGASPRVSSQRIWSNCSLVIFAQSWDSPVEGVSTTLCLQPTVSSRVCNRLRAPNGVNDSRGLDPVARATRLASILDMCAPAIVARGLARARFCTEVQNYTSSEARHLPPWSYCGEGNNWPRIVKHTTSSDLIPSYWFRGFEIMLRSQQGSCGVYLEAFDEDELGRFIQQLKAAFDRLALFRPPDRRVSGIDGLARACLPYYVSWDPFGPFESTAAFNKRQIPSLRALKIHTRPLRTEISHPTTYWSMNTAVVRLAGYVRWQKIIRGVFPNIEHDVWVESQWGMCWGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBI5</accession>
    <name>M5GBI5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_103269</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633218.1">
        <property type="nucleotide sequence ID" value="XM_040767735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBI5"/>
    <dbReference type="STRING" id="1858805.M5GBI5"/>
    <dbReference type="GeneID" id="63682797"/>
    <dbReference type="HOGENOM" id="CLU_347145_0_0_1"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="188"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="664"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="741"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="813" mass="91032" checksum="2487565B68B42E21" modified="2013-05-29" version="1">MDSVVLPSTPLSSHLKEFKRMGDVLKENPPIRFVLYEKEAKSTNLTEKLVACNLPPPADRIGHTHTDEALIAQHPSTKSMITSKDAASKGDVTVRVGEEFAVKRSAPSDIPEPKPGLGIDVTSVKNNTDVRDPVDKVPTARQDLPVTADKTMLRQYDVVKAETSPCQTWDINSRGLKMGWEKYPPPACGLSNGENCCYMNSVLQTLFWCPPFAQALLAEPDSDCCLHNRIKVTAPKEETPYCIFCSAVNLIKRFHTAGRVRDLAADVTKYNTTASEVFGYMDLIMKLKRLREVYEQQDAHEFYSQFIDKLDQAVSDNPTAESKTPTFVDRIFGFKTRQRIQCKHCMKCSDKVDKQRDLPLDIADMAGMTRFKSIFTSLNDQFSKPETFEDDNAYHCENCNAKRSAVKTFKILEAPQVLTLYLKRFAVGSEPGDKFEHHVSYPPKLDLAPYMVEDGSSKLIAPVWYRLASVIIHDSNTTQEGHYFAAVQTLRYDKPVWTACNDEYVRGINKATDQRDAYMLFYIREDEAPTYPESPLKIEVPQNSASVRARAEARVSRIWNIVSRTGKRFAIYENDDEDDLRDGRFKRPRLDGRYPSSPIGKSPSLLRNVKVNVSLPQGPGPRKSWVNMMGSRSLGNSTITGLKVTGSVKAADGATSRPLKIREQMQPNKRRLDVEANANGKRTSDDDDIGSPVKRRQTGRLSLGGDPVPSKAMKTVTRSPASAKIGGMGVSNSLKTREQIRPNNKRDAGHELNGNGKRMSDVPNSGSPFKRARSAEGFAGEEPAFSVNRQRTPIRDYPQRAFPQPQHIFPQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC71</accession>
    <name>M5GC71_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloalkanoic acid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632989.1">
        <property type="nucleotide sequence ID" value="XM_040769526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC71"/>
    <dbReference type="GeneID" id="63684588"/>
    <dbReference type="HOGENOM" id="CLU_045011_3_2_1"/>
    <dbReference type="OMA" id="TCWIERR"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="28316" checksum="5276CB4DA30845CF" modified="2013-05-29" version="1">MSQKETPTTKKLTDFKLLCFDCYGTLIDWETGIYNALEPLLQRTPESRAWSKKQALETFCLVEAAIQEKDPALRYTDVLAETYKELAKDNFGYHPSQNEADIFAASTARWYPLPDTVDALAELSKHYKLLVLSNTDRVIFDQSRRLLEHGFTFDEALLAEDLGHYKPDLRNFEDMLKVAKNKFGIEKDEVLVTAQSLFHDHVPANKLGLASAWIARRDAFIGHAGPEAKYDWKFDSMGDMAATVKAGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCB7</accession>
    <name>M5GCB7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_92268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633034.1">
        <property type="nucleotide sequence ID" value="XM_040777053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCB7"/>
    <dbReference type="GeneID" id="63692115"/>
    <dbReference type="HOGENOM" id="CLU_1749573_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="17086" checksum="6727F725B56473BD" modified="2013-05-29" version="1">MRLCLVRRRRWRLLRHRRRGRRGRRRRERGGRRRLRKVLRGRRLLLGGKGQSDEGISSVLLPTSSSSYRNEFLFDIRSCFGINFGSGVRACGRAGLPYLVFLCVGSCLFGLFGRRLPPSLPLCAFASVRLCLCLCMCIIYAFLCICNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN5</accession>
    <name>M5GCN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_76250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630866.1">
        <property type="nucleotide sequence ID" value="XM_040776193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCN5"/>
    <dbReference type="STRING" id="1858805.M5GCN5"/>
    <dbReference type="GeneID" id="63691255"/>
    <dbReference type="HOGENOM" id="CLU_033011_1_0_1"/>
    <dbReference type="OMA" id="SIAVWYM"/>
    <dbReference type="OrthoDB" id="415889at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032131">
        <property type="term" value="F:alkylated DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000004">
        <property type="entry name" value="DNA-3-methyladenine glycosylase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="5">
        <location>
            <begin position="113"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="42078" checksum="02569683BB148E1A" modified="2013-05-29" version="1">MPTPRTPRKRKLPEEQGTPTLTGNTKRKRNSIVVPPTPLTPSVTTAIVEAIPVAALLEEDILPPCLTFDLEVAKQHIIAADKRFKEVFIHLPCRPFEVLDVVHPFRTLATSILGQQISWKAARSIVAKFLLLFDPSLPERGDVPPAMHDRPFPTPHQLAGMDIPTLRSAGLSQRKAEYVIDLATHFANGQLSPSFLAKASDEQLAEHLIAVRGIGRWTVDMFAIFSARRPDIMPYGDLGVQRGLLKWVLASHDKNYRLAIEPKKLPQPSVEEDPQAAETTDPALQEGDASAIPPIPAETPQKRKKAAKVESPSNAVHVPLGKPVKLPDGLTVSQLKSRLSGKKVQKGMYLTPAEMDALTEGWKPYRSIAVWYMWALSEESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD50</accession>
    <name>M5GD50_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_20842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631151.1">
        <property type="nucleotide sequence ID" value="XM_040772107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD50"/>
    <dbReference type="STRING" id="1858805.M5GD50"/>
    <dbReference type="GeneID" id="63687169"/>
    <dbReference type="HOGENOM" id="CLU_019940_4_0_1"/>
    <dbReference type="OMA" id="HEKHIWY"/>
    <dbReference type="OrthoDB" id="2849215at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06434">
        <property type="entry name" value="GT2_HAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="470" mass="54118" checksum="12BF5FDA03940A2C" modified="2013-05-29" version="1">MLYLTSDKFPIFIPFGVIGFYRYFWYIIRILAFFAYRPVPLPLNPTYVASEDVTIIVPTIDAGEEFIEAARTWLQGDPREIIIVTEERMRGPLEELAAAVDASKIRVLTVPYANKRLQMVEGIKHTMTDIVVFADDDALWPPTMLPYILACFEDQKIGGVGTSQRVTPVGSKLTVWEVLAAFRLSIRNVEIAASTHIDGGVPCLSGRTAAYRTIILKDPEFLHGFTHDLWLGKYHLNSGDDKFLTRWLVSHGWNTYIQCCKEAELLSTMKPNWRFLKQVLRWTRNTWRSDLRSLFKERYIWHRFPYVAYTMVDKLFNPFTLLVGPCLVIYLIVKSTKSVQEGGYHLPWWDIVLSYFVWLLVTRTAKLLPHLWHRPEHVIYVPAFILFGYYFAVMKIFALLTLHETAWGTRAGIGDPTTATKAMDHTSTDPDAPNMPWLQEKTVPEPVASEGIASEMREWDPEAVVYVRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD55</accession>
    <name>M5GD55_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RPA43 OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_40340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631166.1">
        <property type="nucleotide sequence ID" value="XM_040774477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD55"/>
    <dbReference type="STRING" id="1858805.M5GD55"/>
    <dbReference type="GeneID" id="63689539"/>
    <dbReference type="HOGENOM" id="CLU_052539_2_0_1"/>
    <dbReference type="OMA" id="SKMPRIN"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04328">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041901">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPA43 OB" evidence="5">
        <location>
            <begin position="81"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="20665" checksum="4D4E3798E0D16419" modified="2013-05-29" version="1" fragment="single">DQPFVRLHARMTLSIPPKFANNPKKGAEEMLDALVMRYSPTLEGILLAHTQLQFLCPTALLIADSPFSAANVSFVALVWRPRIGMRLRGSVSLCGPDHIGLILERTWNCSIPKWGLDEGVWEYVAGTGAEGEEGAESTDSGWWKTRMSGEPLGGENKTVDFTVVGMTIANQMLSLTGSLLTDPLNPANLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE97</accession>
    <name>M5GE97_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_13295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632086.1">
        <property type="nucleotide sequence ID" value="XM_040770970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE97"/>
    <dbReference type="STRING" id="1858805.M5GE97"/>
    <dbReference type="GeneID" id="63686032"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_1_1"/>
    <dbReference type="OMA" id="TRRSAQY"/>
    <dbReference type="OrthoDB" id="3354175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28446" checksum="C3366FE2D0081EB2" modified="2013-05-29" version="1">MADIGLDTATIVALWCEALLFGVFLVLFAVSVYILWPLSLRTTGRVNGPLLATSVSLFLLLASHAAVCLRRVLQAFVDNEPTPGALEFLSDTRQWTEPVTDLIYGLVTLLGDGILIYRCYVVWARKGWTIIPSVILWIGTVVTCIRSVVMQFELQGGEGIFASQLNGWIEAFFACTMATNGLTTALIVLRIWRSNIDVRKFGHSNLGPVIAIVLESGALYSITVFILLMLYVAQTNAQYIVLAMEIPIIVCPIIPYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEC4</accession>
    <name>M5GEC4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632181.1">
        <property type="nucleotide sequence ID" value="XM_040771678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEC4"/>
    <dbReference type="STRING" id="1858805.M5GEC4"/>
    <dbReference type="GeneID" id="63686740"/>
    <dbReference type="HOGENOM" id="CLU_044538_1_2_1"/>
    <dbReference type="OMA" id="NEYTHAE"/>
    <dbReference type="OrthoDB" id="341300at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16279">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663:SF6">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="78"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="47135" checksum="ADC3A8A4E7BFB53B" modified="2013-05-29" version="1">MRTELIFHGTGASSCLPNISCLTLPPEEYDDDEEGRCEACHQGANPWDHAEPKEALKNRRRNTGAVLRVTQDDGSQVTIVIDAGKSFVAAALEWFPKHGLRKIDAVVLSHAHADAMNGLDDLRCWTLDGTMQDHVDIYLSQKTFDEVERTFPYLVNKGMATGGGSVPEFQWNIISEFVEFDVQGVNITPLPVHHGRYFSPVIENPFPMTPPLSPPLSRSSSTQTFPFPSQALSSSPTPPVVFTSGYFPRSRPPSPVIPQPYIAFAFLLPNILYISDVSLIPPSLFSHLASLPEETKPRVSVLDCLRPENHTSHFGITEAVRAAHELGTEKNYLTGFMCGGQGKWISHRGWLRVCERVSDEKELEDFTEWTGSEGERRRCERAIEMGRKGIEEGKERAWIRPAFDGMRVVIDEHGRVSDGTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFB1</accession>
    <name>M5GFB1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_60679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633006.1">
        <property type="nucleotide sequence ID" value="XM_040775641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFB1"/>
    <dbReference type="STRING" id="1858805.M5GFB1"/>
    <dbReference type="GeneID" id="63690703"/>
    <dbReference type="HOGENOM" id="CLU_085801_0_0_1"/>
    <dbReference type="OMA" id="IKFSRQN"/>
    <dbReference type="OrthoDB" id="37297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02972">
        <property type="entry name" value="DsbA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="205" mass="23071" checksum="2EBCA1F47C20EACE" modified="2013-05-29" version="1">MALLPALKPFCLGQYASPNTLELFIDYNCPYSGKLLRNGVEKTIKPLITNNGKYDGVIKLIFRLNPQPWHASTTFMHEGSVAVALAAPEHWYEFTLALYENQERWFESKAAHLTPTQIRGQIGDLAEQVVGKEKGAVVKDLLTIPGDGNRTNKVTEELKYNIKISRQNGIHVTPSACWNGLHVPTVSSSWGEKEWTEFFEQNVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG36</accession>
    <name>M5GG36_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631697.1">
        <property type="nucleotide sequence ID" value="XM_040771926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG36"/>
    <dbReference type="STRING" id="1858805.M5GG36"/>
    <dbReference type="GeneID" id="63686988"/>
    <dbReference type="HOGENOM" id="CLU_622599_0_0_1"/>
    <dbReference type="OMA" id="MDFLPIN"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="48111" checksum="F315B7BA478F881B" modified="2013-05-29" version="1">MLSPHTPIPSEPYGFSMLPVRYSLRSMRRRRSTDSFTSYASEESGLSGISGMSSLVLEPPEWQEEHEKVLGRALDSLPDYLTTPYVGNIPPPNLLQNLAKGILKDMKENKTGWPYTLAQTRAKLREIAEVKARELRELGRDPERADGANKRSLHRSDSMDFLPINGKDRVAAASRRMQRLDQILDPTLRPPNSSRSSRRTTAAAVNEEPPQTITITYQSLPRPLIRTRTNVAPLAPVTPSVIDIPPPSTPALRRMASSTAVFEPAGSEPATLRALKRAPSYGSSADVPEGSPDANNPTKKRKTAAKKTRSPSFLGGPLPGLAGLFPPESSSAVLMSPETIVTPHTPVRRTVATRTRSTPAGPPTISPQSTPGRVRTRSQTKADAHAATAAQEAFERESQKSAEHDKENTPSHSRRSRTAVRAKKDLPLDSPFEEIKRVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD5</accession>
    <name>M5GGD5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_19850</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632192.1">
        <property type="nucleotide sequence ID" value="XM_040771685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD5"/>
    <dbReference type="STRING" id="1858805.M5GGD5"/>
    <dbReference type="GeneID" id="63686747"/>
    <dbReference type="HOGENOM" id="CLU_015166_4_0_1"/>
    <dbReference type="OMA" id="NRRMYRG"/>
    <dbReference type="OrthoDB" id="2382881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="37"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="130"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="243"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="357" mass="39203" checksum="7BBB38CB0276EA12" modified="2013-05-29" version="1">MDRDSDGSAAKPGPISPYRWDSKRMNDGFNYFLLNNRTAVCATVGSLVSTLLGFPLDSLKSRLQAARTPVTPFLLATNVFREEGIGGFFRGVWIPLLTISIVRTASFTIYSGTKEYVHRKGILAGNSLKDVAFTGAVAGAASGSSICFGSAPFEIVKVRRQLEYAIAQARGLTIDKPPGTWSAVMQIVKEKGVLGLYQGFRMHFIRDTMGTSLYFLEYDSFRYLMGRSISGEQGPPPSWLPVPTALIPFFCGSVAGVTSWAIIYPVDVVKTKIQQRALANQPYRTVWVTFQRLIRGPDAEHPRPLLVGIGRLYRGLGISAIRSCMTHGALWLIFDWVAQWIDQRTAGMPGAGRGPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMZ6</accession>
    <name>M5FMZ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endopeptidase S2P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_120048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623458.1">
        <property type="nucleotide sequence ID" value="XM_040770924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMZ6"/>
    <dbReference type="STRING" id="1858805.M5FMZ6"/>
    <dbReference type="GeneID" id="63685986"/>
    <dbReference type="HOGENOM" id="CLU_021808_0_0_1"/>
    <dbReference type="OMA" id="WFARCER"/>
    <dbReference type="OrthoDB" id="7694678at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031293">
        <property type="term" value="P:membrane protein intracellular domain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905897">
        <property type="term" value="P:regulation of response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325:SF3">
        <property type="entry name" value="MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01000">
        <property type="entry name" value="SREBPS2PTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M50" evidence="7">
        <location>
            <begin position="179"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="553" mass="60077" checksum="4D22E00540D4B007" modified="2013-05-29" version="1">MAVVIPALLLALFWVVVHLIHRLTVQRFLTPLLPRTRPLTRSSGPGSCFDPDYTSFHLSYVNLKLETTAFNAAHERLSGYLVNHGWLSFGKALYGVGAVIGIVGMFASLCIVAWTGLLVISETFLDTSVTPGLPPIARKIASRAISALPASLAPDSQASLALRPLIPGVTIPISHLPLMLIALFICQSFHEFGHAISAALEDTPLHSVGLALHVIVPTAFVSLKEKPSTTPSANLRLASAGALHNIFLWIAFYALAHSGLGRLATPIGWTDVSSLGKVVLGFNEATSLDGYMPRGSLVVQLDDTPLGQSARNAGQGDPWETFLLSKAPQELRRGWCLDSSEFVGSPTACCSEPSTAELTCFVPMSAPPSEYQGHCLSPLSLFNRNNTTPRRCDPAGCPGQDLCIVPSAESQLLRIAFVDMERGKERVVVWKGPRLEVYRQVRVGTYLPRTPLIPFWLPDLVNLFISYNLTVTIALYLFNLLPLPLLDGGQVLSSLLDLLFGADPSLGADINFNHAPWQRRNRRERIERAFHWGAGALCITVALAVSVKELTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN21</accession>
    <name>M5FN21_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_25523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623583.1">
        <property type="nucleotide sequence ID" value="XM_040774197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN21"/>
    <dbReference type="STRING" id="1858805.M5FN21"/>
    <dbReference type="GeneID" id="63689259"/>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="MDIPRPE"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07857">
        <property type="entry name" value="STKc_MPK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="434" mass="48993" checksum="818BC142538E2866" modified="2013-05-29" version="1">MSHRHTFTALNQSFIVDSEYDFVKELGQGAYGCVVAARHRRSGEGCAIKKITNINTKRILTKRCLREIRLLHHFRGHKNITCLYDMDIVYEPNGDYNEVYLYEELMEADLHAIIRSGQPLSDAHFQSFIYQTLCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGWQPGPGTQQHSNKGQQGFMTEYVATRWYRAPEIMLSFANYGPAIDIWSVGCIFAELLGGKPIFKGRDYVDQLNQILHYLGTPSEDTLRRVGSPRAQDYIRSLPIKPRIPFQSLYPHANPLAIDLLSQMLCFDPAKRISCEKALEHPYLAVWHDTADEPLCSQTFDFGFEEVDDMPGMKQLIIEEVNSFRALVRSQARQQLQARKQDSLPIPSRDDILASPVVENDGTSGYTFPHPSAPGPSGGMVEEPGAELDKELGAYGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN76</accession>
    <name>M5FN76_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_91905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3"/>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623858.1">
        <property type="nucleotide sequence ID" value="XM_040777031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN76"/>
    <dbReference type="STRING" id="1858805.M5FN76"/>
    <dbReference type="GeneID" id="63692093"/>
    <dbReference type="HOGENOM" id="CLU_036645_0_1_1"/>
    <dbReference type="OMA" id="MGMEDTN"/>
    <dbReference type="OrthoDB" id="425211at2759"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="32870" checksum="379B0E8CDAB99CB9" modified="2013-05-29" version="1">MFTAIRPITNSFTVKLATGQGGVWTSVRRMSVRPEAPSPERADRKKVTLQHLRQLHATRTAITMLTVYSYPSARRADQADIDICFVGDSLAQVALGHDNTTRLTLDEMLHHCRALGVKEALATAVRLVKEGDMEAVKLEGGDEVVDVVRAITAAGIPVMGHIGLTPQKHTSLSGYKVQGRNAQDALSIARSAKALEDAGVFAIVLEAIPSLLAEEITGSLRVPTIGIGAGMRCSGQVLVQDDALGVWGGGRKPKFVRRFAQVGEEALKGVEASAMAVRKGQFPADEEAHTMPQDELNKFKDNKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN91</accession>
    <name>M5FN91_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623933.1">
        <property type="nucleotide sequence ID" value="XM_040774164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN91"/>
    <dbReference type="STRING" id="1858805.M5FN91"/>
    <dbReference type="GeneID" id="63689226"/>
    <dbReference type="HOGENOM" id="CLU_852641_0_0_1"/>
    <dbReference type="OMA" id="LWNSQHH"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="326" mass="36340" checksum="6CD66F50395E84BB" modified="2013-05-29" version="1">MPCVCLSHPSCPVCSNSGCRWNTLLRRGTITSIWRIFTGTRTRSVQRSRRSYPVSSSGKTCGSPARCAFSRCRGCMLTWGKLWNNAHKPEEVEKQLDESLRQIGTDYLDLYLIHWPVAFVPNRGVVPKANEADTEVELDLETSLVETWKAMIALPKSKVRNIGVSNFSVAMIRAITAATGVLPAANQVECHPYLPQNELVEYAKETGLHLTAYSPLGNNLKNVPKLTEHDVIQSIASSIGATPAQVLIAWAVARGFTVIPKSVQNDRIESNFVQVDLSPEDVQKITAIGEKEHTRFNIPYYFVPRWNISVFGEPSEKEAKNQIKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNC2</accession>
    <name>M5FNC2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624088.1">
        <property type="nucleotide sequence ID" value="XM_040774109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNC2"/>
    <dbReference type="GeneID" id="63689171"/>
    <dbReference type="HOGENOM" id="CLU_2359690_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="96" mass="11172" checksum="839375767AF2F4FB" modified="2013-05-29" version="1">MHARVQSFLSRVHMVVVVVVALRTGGDVRFFRIIRTVFCAHPSLLRNVAHIFIRYNAKRMQPISPILIIVALILVYLAHLPLLYLQRRLHSETQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNE0</accession>
    <name>M5FNE0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_111826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624178.1">
        <property type="nucleotide sequence ID" value="XM_040769291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNE0"/>
    <dbReference type="STRING" id="1858805.M5FNE0"/>
    <dbReference type="GeneID" id="63684353"/>
    <dbReference type="HOGENOM" id="CLU_015421_0_0_1"/>
    <dbReference type="OMA" id="INTHAHH"/>
    <dbReference type="OrthoDB" id="4454541at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="275"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="941" mass="102296" checksum="B3A7BB6627D659DB" modified="2013-05-29" version="1">MSKPPVKKILPSGQPPPPQPMQPHTGTGTGVQRAVLRVNRACTSCRKHKMRCEGADHPPCARCRSSGIECVFESIKKEHALDSVAVERLGALEREFRSMQGTMREILGAIRGQGQGGNANGNGNGNLGGAGSAGNGTGSSPPQLSHAASSNSNPSPAAGTELAAHLSPIYTHTPSPPHSHSQGMTNHHPHSHTHSHLSQSHHPLPQAQGHHPHPHAHPHTAFQVHSPSFLNGGSHVSPSSAHSVSHSGSTINTHAHHPPLVHNFLPSPDIADLHSAHAHSHAHAHAHARSPGRRRTGDQFKSIPTSAATSDDEGELPGKAFLAPIEVLSDLATAAAAQAGNPSPEESGPNPKKRKLNDGRPLPGGEDGSVEGWDGGRDRGRGGESERGRERERERREGRDVVDKGIVTEEEARELYRIYFSGCYRFLAVFNPEIDTFPSLRQRSPFVLCSILMVASRVRDGGSPPSRVHTELFQEASNLARDTLFSQPQGVECVQAMLLLAGWSSKTGWLAAGHGIRMGMEIGMHKALPRLAAKMRSGRHDPSPDPKTSLDAALVSQARTWLGLFVFELQIGRGTGRPAMIRGDKSISDARVLLTHPCGILTDARLVSTCELLVIQARIHEMLDEERDYDKVVTILREGEREIDDWHTEWDFIMSEKHPDAAGFFRSSAQIQRMYAVLFMHSVALRELRTVLDAKEHPQMHEVMMTAVHNARGCIEICLEAPEYREGLRYAVTYTHTSAAFAAAFLLRFARLFPHEVDIEDSIRMVESLIRLFSESEPIPLNQTSSSLSLIHAFLVPAARFVSPLRQMVEYTHKRWEELKSGIDLPSSLRIAPTPPSHFTNDFQSIMNPPPPPPPSAAPASAPVFDAGMSMFPVDPNSSTMEWAAAVNMLDGFGLPPSMSTNGGSLGWLPNSILGDLAVPPSATEADGNLRDWNLQFAFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNH8</accession>
    <name>M5FNH8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AAA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_85045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT97470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040776714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNH8"/>
    <dbReference type="STRING" id="1858805.M5FNH8"/>
    <dbReference type="GeneID" id="63691776"/>
    <dbReference type="HOGENOM" id="CLU_000688_8_1_1"/>
    <dbReference type="OMA" id="GLWSTHR"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000018">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000365">
        <property type="entry name" value="Ribosome biogenesis ATPase RIX7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="158"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="476"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="760" mass="82306" checksum="8699E59FCBC70EC4" modified="2013-05-29" version="1">MALNSSVTSLWSSHRQRTKINLNSISSPTIPVPLVAPTDALQPGPDLVPPEIAEGLPTAPGTPPSQPPTPPPETSAPFNLAQATVTDLPVSSSRKRPAPVAKASSSKRPKPTPIQERPPPSVRLSQLGGVQAQIDQLLRAIGRPLRFPELYLRLGTKPPRGVLLHGPPGCGKTLLANAVAGELGVPFIPVSAPSVVAGTSGESEKALRGYFEEAAKLAPCILFFDEIDSITPKRDNAQREMERRIVAQLLTCMDEMSWEKLDNKPVIFIAATNRPDSIDSALRRPGRFDLEIEMPIPDENAREQILRVQAEKLTLSGDVDFRMLAKLTPGFVGADLEALITAAGECAADRIFSELIQVPPTVPIVEENAEGDVSMDDAQLVPATKPNVSSTFSSIFFSIPHPLSPEALAGLSLTPADFMTAIPLITPSSKREGFPSPPSTSWSDIGALHGVRQELHMAIVQPIRRPEVFKRLGISAPRGVLLWGPPGNGKTLLARAVASEGRAGFIAVKGPELLNKYVGESERSVRAVFARARASSPCVIFFDEIDALVPRRSDKLSEASTNIVNTLLAELDGLSQRKAIYVIGATNRPDMIDPALLRPGRFDKLVYVDLPKSDERVEIGRTVVQREKVPVRGGLDGEDWKAVEMLLAADQSDGMSGADITALITEAASTALRYALGEAMQNGDQELHGPSTEQSLREQAEAEGIYVERRHFEEAFGRVGRSVGESMRHRYETLRRKFEGVRVRGKGIEEDKDGVMLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQF6</accession>
    <name>M5FQF6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624581.1">
        <property type="nucleotide sequence ID" value="XM_040773977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQF6"/>
    <dbReference type="GeneID" id="63689039"/>
    <dbReference type="HOGENOM" id="CLU_1503390_0_0_1"/>
    <dbReference type="OrthoDB" id="3346965at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="179" mass="20214" checksum="1366C1C635E806E3" modified="2013-05-29" version="1">MQRIIDYSQEDDDATPMEIEHDPFTPNTLYIAVYATEREGKLQEDLGMMFCAVTPTAGTYFIAQPRPADGKFILNMTSTYPADYTIRGWYPIGNRPVEYRETTTANGKVNGVRRDITTGESWLWTARLLRSFSEKPDTINWGAVIPVVVARTHIMSDECIENMVGVVPGLEEAIQNKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQI8</accession>
    <name>M5FQI8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_59730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623902.1">
        <property type="nucleotide sequence ID" value="XM_040775583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQI8"/>
    <dbReference type="STRING" id="1858805.M5FQI8"/>
    <dbReference type="GeneID" id="63690645"/>
    <dbReference type="HOGENOM" id="CLU_017390_2_1_1"/>
    <dbReference type="OMA" id="YGRDRCA"/>
    <dbReference type="OrthoDB" id="6407164at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000120">
        <property type="entry name" value="Negative regulator of differentiation 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000400">
        <property type="entry name" value="Negative regulator of differentiation 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF8">
        <property type="entry name" value="RNA-BINDING PROTEIN MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="14"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="106"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="245"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="336"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="499" mass="53762" checksum="E6ECBCF7ED1F7E3C" modified="2013-05-29" version="1">MNPLGGAPLNPNQRTVYIGNLPPTGTIDELLSLIRSTGPIESVRLLPEKNCAFISFLDAPTALGFFNDASAKKLQLHGMELKIGWGKATPVPPTVAAAVMQYNASRNVYLGGLEDYVTEEMLREDLGRFGPIDQIKILKDKNVGFVHFLSVQSAIKAVSQLAQEPNWQGKRVNYGKDRCTYVPKGQKMQPQIPQQPLIPAAAIAAAVNMGQNIPFNPAGTPQQFMQVPGSLAAGFGASGAVPNMRTVYLGNIHPDTTTEDLCNAVRGGVLQSVRYMKDKHIAFVTFIDPSAALAFFNIASLQGLSVNNRRLKIGWGKSSNPLPPALAVAVQGGATRNVYVGNIDDWEKWAEDRLRRDFGEFGDIELINSLREKNCAWVNFTNISSAMKAIEAMRVRPEYAHLRVSYGKDRCANPPRAGVQGGGSRRNNNGGVSPLSGTEKPGFQEVGEQGPAGEAASTAPGSSGGFVYAYEEADADEADAREAEHDMIVPSDEVLEGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQK1</accession>
    <name>M5FQK1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LSM complex subunit LSM5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">DACRYDRAFT_111300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQK1"/>
    <dbReference type="STRING" id="1858805.M5FQK1"/>
    <dbReference type="HOGENOM" id="CLU_076902_6_1_1"/>
    <dbReference type="OMA" id="YETTPQG"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9499" checksum="5FCBA4BB05FAB3CD" modified="2013-05-29" version="1">MASQILPLELIDRCIGSRIWVITKTEREFAGRLLGFDDFVNMVLEDVTEFITTEEGVKKVKLQQTLLNGNNICMLVPGSNGPEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQL9</accession>
    <name>M5FQL9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_32505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626088.1">
        <property type="nucleotide sequence ID" value="XM_040774359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQL9"/>
    <dbReference type="STRING" id="1858805.M5FQL9"/>
    <dbReference type="GeneID" id="63689421"/>
    <dbReference type="HOGENOM" id="CLU_945102_0_0_1"/>
    <dbReference type="OMA" id="YEWANEL"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="108"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="295" mass="33738" checksum="67E8A41C66944512" modified="2013-05-29" version="1" fragment="single">FEVFQATWRYPDWRGSLGTAFHFVFDGADDSAGKSLVKDIYEWANELKKEIWVFSHGNWSKDSDLYETVQAASWFDVVHEPGFVEALKSDTETFFASEKVYAAIGVTWKRGILLLGPPGNGKTQTIECLLKDLLAQDISPLYVKNFKTDRDEEWGIRAIFEKAREEAPCVLVLEDLDAMVRPRVRSYFLNELDGLARNHGILTIATTNHPEKIDDAILRRPSRFDQKYTFALPSLALRQEYVRIWIAKVTTQGGFGFRSGADVLSKEVAEKTEEWSFAFLKELFVSFLLRSATDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQS2</accession>
    <name>M5FQS2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Creatinase/aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_118045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626198.1">
        <property type="nucleotide sequence ID" value="XM_040770512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQS2"/>
    <dbReference type="STRING" id="1858805.M5FQS2"/>
    <dbReference type="GeneID" id="63685574"/>
    <dbReference type="HOGENOM" id="CLU_011781_2_3_1"/>
    <dbReference type="OMA" id="EPGMILS"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="7">
        <location>
            <begin position="323"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="9">
        <location>
            <begin position="552"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="615" mass="69545" checksum="769105E8BDE1AAC6" modified="2013-05-29" version="1">MVQTKSKTVPTTERLKALREFMRRPECNVQAYVIPSEDQHASEYLADCDARRAWISGFSGSAGCAVVTLDNAHLFTDGRYFLQAEQQLDSNWQLMKQGLKGVPTWQKFLSENLPKGTKVGIDSTLISAEDARVLKEDLGKKDSSLVPVSWNIVDRIWLDRPARPKNPIIAHELEYAGKSSTEKIKEIREYLVKNNFSSIVVSMLDDVAWLFNLRGSDIAYNPVFFAYALITDKAAILFVDPAQLTEEVRKYLGSEINIQPYDCFWSHLAEHKSTLSVNPEKKILISRTTSWAIARALEEQRVAVGRSPVADLKAVKNEVEIEGFRQSNIRDGAALVRYFAWLEEQLHQHKTLSETDAADQLEKYRSEMELFMGLSFPTISATGSNGAIIHYQPDRNDCATIELDSLYLCDSGAQYKDGTTDTTRTWAFGIPKEEEIRAFTRVLQGHMAIDMAVFPEETSVDIRDAFARRPLWIDGLDYRHGTGHGVGSFLNVHEGPHGIGQRIVLNDTALKAGMVVSDEPGYYADGRFGIRIENVIIVRKADTPNRFGDRDYYTFEHVTMCPIQTSLVDVSLLTKAEKVWLNEYHTEIEQKLLPLLEAKHDERAITWLKRQCAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQS6</accession>
    <name>M5FQS6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_119114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624821.1">
        <property type="nucleotide sequence ID" value="XM_040770727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQS6"/>
    <dbReference type="STRING" id="1858805.M5FQS6"/>
    <dbReference type="GeneID" id="63685789"/>
    <dbReference type="HOGENOM" id="CLU_008964_4_1_1"/>
    <dbReference type="OMA" id="QNTHYLQ"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="42"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="655"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="84116" checksum="546E49FCE669973F" modified="2013-05-29" version="1">MGDMQAVSGQRNADISNSLYALHARQLFDVIDQIRDSGGEHHLDLPRIVVIGNQSAGKSSLIEAIAGIKVPRGSGTCTRCPMEVRLHRKNEPWRCSIRLRYEYDEYGEKRDDPLNINFGNDIVDPAKVDIMLRRAQLAILNDEDNPGKFVDIDPNNMAVSDSQRQFSRNVVCIEVFGPDLTDLTFVDLPGIIQHHPTDPGLVNVIKGMVKAYIAGSSALILCTITMKDDPENQAALSEAKTADPHGARTIGVLTKPDTLQPQEEGLWITVLKNEGSHRLNLGYYITKQPAQAEVEQGISFDMARQNEVSFFETTEAWRALPSSIRQTNVSTPRLTAALSTLLSSHIRKSLRDITEKVHRLLSETQRDLRSLGTGPSNNPVADIIALCDRFTGILRAYIVGTEDSELLIQDNKRAFSRFKTSIRGTAPVFIPYTTVERKWNEYTEPTHILEDVATEDNGHTYDLDMVRKHINNAKTRELPFNVPYAAKVQMMLLPIKRWQTLIDVCFEAIVPNVRSLIEKTIKQVFGEYAETGLLGRVKDIVSNQLIERENATQIALKLLFDMEVPGPYTQNHHYFSATREKLVTHYRQKRKERESAPTRPTSAWGLAPSEYASGPTTSRSTIINQVISGLATLGFQGVTESDFGKLVIEDEWEEEITVMAETRAYLQVAYKRIIDSVPQAIDLVFIRPLADTLHTALIAGLQFDSPSAHELCRAYLAENPAKAAERVRLLADKERLERVKETLMRIGLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR27</accession>
    <name>M5FR27_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_23632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626398.1">
        <property type="nucleotide sequence ID" value="XM_040773318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR27"/>
    <dbReference type="STRING" id="1858805.M5FR27"/>
    <dbReference type="GeneID" id="63688380"/>
    <dbReference type="HOGENOM" id="CLU_033167_0_0_1"/>
    <dbReference type="OMA" id="INTHLQH"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="8">
        <location>
            <begin position="291"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="545" mass="61563" checksum="B8C43993AC2BB9AC" modified="2013-05-29" version="1">MSARLRFFQGFFRRPSSALALIAASFLVYIVSQSGVIHRTPTHTEYLGEHNIQQVLVDELPLKDDFDSNSWSCPSHPGEQTPACSNAHFFPPPQARTIVPSSLISFTPGWTLLTNLYFSNGTFYIVSSEGGFGEGYWPERRLITSTGLAGDHSNGAEREPTEREMDILTQEQAGEIWGDRVFDIQGFSVLANDPNQFLQHYYHVAAEILLGIERVCTNFDPMPGPDGTVSAPSPERLIFLHTDEAGFTDWPGLDRFYLHAQWPHITPLYQPSWEAMASLVSDSRKAWRFPAALFIDRSASFRGPYTEVTSRTPAGPWAAGGGKFGTGGEGRNRFWYESARRRVLSFVGVDREVLDVGLRAMDPPLAPLRRDGKEDVYQVTYISRQRTGRRLIDGDHRRLARALRYMCNKHGWKFFLMVAEDMDREEQMRVAAETTVFVAVHGNGLTHMLLQPPHPRAAIIEMFHPPGFARDYEWTAGILGHRYYTVLNDTAYTPPDLAKQQYPDWLFGKDIPVQAETVVAVVEKQLLGPIPGPAHWQSWREEVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRB0</accession>
    <name>M5FRB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Root hair defective 3 GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEY1</name>
        <name evidence="12" type="ORF">DACRYDRAFT_25199</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRB0"/>
    <dbReference type="STRING" id="1858805.M5FRB0"/>
    <dbReference type="HOGENOM" id="CLU_011270_0_0_1"/>
    <dbReference type="OMA" id="PIIKMTE"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="673"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="694"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="718"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="11">
        <location>
            <begin position="48"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="745"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="769" mass="87046" checksum="2EE2279CFA242C3C" modified="2013-05-29" version="1">MISDSVQTPSITNGHADASMRVQVIDEDKKFNADLSKWIDKWGLRSAGFDYDVVAVFGSQSTGKSTLLNKLFGTTFDVMDETQRRQTTKGIWMCRADDLPVLVMDVEGTDGRERGEDQDFERKSALFSLASSQILLVNLWEHQIGLYQGANMALLKTVIEVNLSLFGKTDQKTLLLFVIRDHVGATPLTNLSATLTADIERIWASVSKPEGLESRLLTDYFDLEYVGLAHKILMPDKFEADVKSLRTRFTFGPTGFFKERYRRRIPADGVGVYMDSIWEQVSSNKDLDLPTQQELLAQFRCDEISKAALEAFTSRAKEGRRNLEGGKAVANLGGMMRDWKTEALHRFDTEASRYHAGVYKSKREDLTAALHAYLQPLFMAQLKNLHKSSLALFKVQLEEGLRKDGYDFATVVGDARTKSQTAFKEGADEVLIPDADWDYDLELQQLDEDLTSLTALSKSDEMKKMVNSIERTFKREIGEKVDLELGRPGPKMWDTVLTVYSAALQKAEQAYVKKAKSFGSTPDEDAKSLLTLRQRAWRALKVKVDEHTTETLLLSKLRASFEEKFRYDENGVPRVWSKNDDIDGLFRKSRDETVELITVYSRIKPSNPDLLPAFPPEEEFSGIDGNDEPFEFEESLLILSEAKQVDITSKFRREADAYFVEAKRSIVSSIAQIPYWVYGIILLLGWNEAIFVLFHPIYLFTIIMAGAAAYAIFQLNLAGPLFQISRTVTNELQRQAHGRLKEYFADPPASPSGDLRQRRVSPGTEMLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRD4</accession>
    <name>M5FRD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ras GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_119220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624427.1">
        <property type="nucleotide sequence ID" value="XM_040770745.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FRD4"/>
    <dbReference type="GeneID" id="63685807"/>
    <dbReference type="HOGENOM" id="CLU_000972_1_0_1"/>
    <dbReference type="OMA" id="KGVLVHW"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903479">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="94"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="842"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1322"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1497" mass="171212" checksum="BBAB92E5591831F5" modified="2013-05-29" version="1">MHTHTRSIALQDHRRSYDYPTDRTREVYGVPGRIRLSRNISGPLVPGSPVRAETVTQPSTPNSQDNTGTPRKKISKFALWADRKREDIQAYEYLCRVGEAKAWIESVMGVEDGMEITEWEEKMRDGVALAKLVKQWGAPGKVFEHPRLQWRHSDNVNMFLNYVRGVGLPENFVFEFTDLYEKKNMPKVIYCIHALSYLLARWGIAHHIGSLLGTLEFSDDQLAATQKGLKAAGVAMPNFGDVGKELWKEMKEEPMETEEDRIERELLEQEPKIVLFQTIARGFMARQRCAEILSRLDRLEPSTIAIQALCHGWLTRCRITKHRRNVKAAEGKFVIALQSQARGVLARARRKQYKRDLARPSTLKVITGLQSRVRGAIARNRVLELSKKMDHVEPAVVWAQTVLRGVIVRRKIREQLGKLDAIEPSIIRLQAVARGALVRRRRRMQEEQQAKPQVVRSIVSLQACARGLLKRRKAAEMSKEIGAVIPSMVGLQSQIRGGMVRQRLRAQLARLDSHELAVVRFQAVARGYLARKEYRSMATSLRKAMPLFVGLQARTRAMLAKKRAQDVEKALANVQVVQAVSSLQAFARAALTRKRHQEQAKQLEFVAPDVLGLQAQCRGVLARRAFGWWWHYVHEHQAEATNLQALCRGIIVRRRFMEKINYYRANLSKVVKIQSLFRAKEQREQYRQLTMGQNVTVSTIKNFVHLLNDSEFDFEDEIEVERLRKKVIEAIRENQHLETYVTELDVKIALVVQTVKSVEELVKARRWGSIDSSGAHTSRAAVLAAHGDPFAGPSTLDIATKRKLELYQQLFYLLQTKGEYLARLFFRMSRVEMPEKTKRTVERVTLILFGYGQRREEYLMLKLFQHAISEEVRSAPTISDIVDSHPMFLSIALQYVRPKQVTWLRETLRTLVEEVVGQPAFNLETDPIVIYRAVINAEEMRSGVSSGKPVDATFEEAAFDPHTRGEWIRHLQMLRHYTEQFLNAITNSTRKMPYNIRSIARDLLASLKTKFPGQSDRVYATAVGKFVYYRFIHPAMVAPDAFDIVPNTIGAAARRNLGEVARMLTQISSGSAFLENVPSLIPLNAFVNTAITQTQKWVIDVAELQNPEEHFKAHELLDATEQPSSIVISPNEVYAIHSLLAQNLDHLTTGYDDTMRVIITELDGVPHLGSDELRDARDRPVTLELTNRFADVKDPNAGEKALWVHAKRGVLAVLRVQPAKDLMTSLMAPVTDEQDAIWEEIIAQELPSEEERSKKSRLPATTTTDPAYRLEDIRTQSYRDIKAQAMFYLLELEKLGKLTRTNGFQGVLNAIAGDVRSKHMKRMQRKNELESMEEALRHLVERKKAFEDQINSYHSYIDSAMNTMQRGKGKKRFVMPFTKQYFHLRDLHKAGKNPQFGSYKYSAQELYDKGILLSIDKFSPRQFDRIDLVISSDQVGDFTVEMFNNTYGTSAMSSTTLRMEDLLQSQFENRVSLSLFDGLAKVNLNLLLYQINKKFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRD9</accession>
    <name>M5FRD9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_58988</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624437.1">
        <property type="nucleotide sequence ID" value="XM_040775530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRD9"/>
    <dbReference type="STRING" id="1858805.M5FRD9"/>
    <dbReference type="GeneID" id="63690592"/>
    <dbReference type="HOGENOM" id="CLU_015676_1_0_1"/>
    <dbReference type="OMA" id="TITHCEW"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF26">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="589" mass="65388" checksum="06E9E5C67819F14E" modified="2013-05-29" version="1">MAKDLPTHPTLGGPPPPSVDAGQAWFTSFSNAISSCDVLALLGLIREDGFWRDMLALTWDFRTFKGTERIKEFLHDRLQGAELSSLKLSNDFPPNLEQPWEDVTWLIITFTFSTKVGTGTGIARLVFDHKPGAWQVYTIFTTLSGLHGVSEALGSNRLMQPNHGQWLSSLAQTLEFEKDPEVLIIGAGQSGLDVAARLKMMGVSVLCVERNARIGDQWRGRYEALCLHDPVWYDHLPYLPFPSTWPAYTPAAKLAQWLEFYAQALELPIWLSSTIESCTWLEGEGKWEVVVQRGAEGGKKKRRVMKVGQVVYAAGLAGGVPNMPKIAGMDEFRGKIVHSTQHKTAKDYVGKKVLIVGAATSAHDIAHDFANHGIDVTIFQRDSTYIMTTKHGMPVVMRGLYWEGCPPTEQADMLSASLPNEVLRHVHKRYTQEVAEKDRELLEGLDRVGFRRNEGVEGSGFLFLAYSRGGGYYLDVGASQMIVDGKIGLKNGCEIDRFTPSGVRFSDGSEIAADLVVFATGFGNIKESMRSMFAPDLVERLKPVWGVDEEGEIRAAWGDSGHVNFWYMMEIKAMQMGVSGDRYQKGKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRL1</accession>
    <name>M5FRL1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal biogenesis factor 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_117454</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626698.1">
        <property type="nucleotide sequence ID" value="XM_040770386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRL1"/>
    <dbReference type="STRING" id="1858805.M5FRL1"/>
    <dbReference type="GeneID" id="63685448"/>
    <dbReference type="HOGENOM" id="CLU_049216_0_0_1"/>
    <dbReference type="OMA" id="AYHPTVA"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="28205" checksum="18E029A468563A89" modified="2013-05-29" version="1">MSKLILDPASHLLLHPTLNTALKVLATTTGRDKLQRTLQYYSRFLAYVYERRGLVEESKRWNGLKGVFGNARKVLRMFKFLEHLQSALRLSLSTSGDWAQITQIARQVGYAGFLFFDHLGWAGNVKLLRMSKESVERANKLSQRFWLAGILLSLVNSGERFAQIRAERKRLTAPTTAEKETPEAEKKLRLHTLTAEFSAVRMQFVQDTLDFWLPASNLGIVSVSEGFAGACGTITSVMGFYQAWKKASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRV6</accession>
    <name>M5FRV6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNase I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24769</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624692.1">
        <property type="nucleotide sequence ID" value="XM_040773843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRV6"/>
    <dbReference type="STRING" id="1858805.M5FRV6"/>
    <dbReference type="GeneID" id="63688905"/>
    <dbReference type="HOGENOM" id="CLU_060600_0_0_1"/>
    <dbReference type="OMA" id="WNINGIS"/>
    <dbReference type="OrthoDB" id="3357826at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
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        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="92"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
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            <position position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
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            <position position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
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    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
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        <ligand>
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    <feature type="binding site" evidence="6">
        <location>
            <position position="267"/>
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        <ligand>
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        <location>
            <position position="269"/>
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        <ligand>
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        <location>
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        <ligand>
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        </location>
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            <dbReference type="Pfam" id="PF03372"/>
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        <source>
            <dbReference type="EMBL" id="EJT97794.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="44594" checksum="9FB82CD15B6E1FB6" modified="2013-05-29" version="1">MSKRNLAISEVTPERETEAEIPPAKRQRLNPSSKTRSVRTPSPPRRDSEERTRIISWNIETPIPFLDLRYTISSTGMSSYLVHPPRRIPENDFLRMLLKEWDWPEFVCLQEVRARPTDKDWMTAMCAAANGVSPLDRDGETDRREDGGPTYTAYWALNVSRRGQRRFGVCTLVAHPWVKRVRRERTVGWDAEGRVHILEFDGWALVNVYALNGSDFPWVDPRMEGDPLAKVLPQKTRNERKREFNMLLLEEIQTMRARGLRPVLIGDFNISLAKVDCYPRLRTQHPHALARKQFNEVFIPQAEVVDVYRAFHGSETAYSWFAKGKPVGSDAARVDYALVDRQLIREKGEGREMGTGYGGKNVGKSDHGIVWLDMCGMNNLGLSEARAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSB1</accession>
    <name>M5FSB1_DACPD</name>
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        <recommendedName>
            <fullName evidence="5">RxLR effector protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109020</name>
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    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067184" description="RxLR effector protein" evidence="2">
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            <begin position="20"/>
            <end position="176"/>
        </location>
    </feature>
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            <end position="132"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00281.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19596" checksum="ECC6A221B2BDB529" modified="2013-05-29" version="1">MVRSSTIVLTLTLAATAFAAPLSLERRSAPMEEHEQFAMRSEMDAASLEKRFDFMHHLHTALSWVKSNPKKSAAGAAAVVGFLGHHIWKKKQDKALTNAQPARQATDGEVPDESPTDGGSGGDASKYRRRDLQDDDEYLLEMRDMEDNTPWVVLRDANMEYVASTLEKRGSLSDME</sequence>
</entry>
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    <accession>M5FSE8</accession>
    <name>M5FSE8_DACPD</name>
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        <submittedName>
            <fullName evidence="5">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
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                <person name="Sabat G."/>
                <person name="Salamov A."/>
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                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574:SF40">
        <property type="entry name" value="WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="88"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="135"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="440"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="571" mass="63463" checksum="CFD929890A7231D8" modified="2013-05-29" version="1">MPHLNALSDLRDSSPLGKRRRSEDNIDASPDAQHTPLPHSLHPRHLSGSQGLPNMPSLRREGLVADTLRVRRRAMDAALGSFQYSTKLKAHKSCINALTFSKGEGRWLASAGDDRTVLLWDMYDDEQPREPKAKLRGHRSNIFTLSFNASNTCIYSGANDDIVLRYDLSRLGDPQSGVLVSAPDEVFLEQNGAIHSVSAHPYNDHTLLSASEDGLIRFEDCRDPAPNKRCITNNAGFSDVKWHPTDENLFVSTDQKGHVTLHDARTAFKTTPTSRADAAVSNYITTISLVLGNNIEAIAGPEASSVSFASTGSMFVVELLLYGPVMYSLSDPSPILTLTADNLPSGQPIPAGQRSHANKCTTKHGSFGGDEQGSLYYGTGSDDFRGYCWKIPPLQTLLDRRQEIDAASWKTGPMVSMAFAKSETTNKYLPERMPTPSYRLEGHRSIVNTVLFHPTQPLIATSGIERFVRLFTHFPTQPGQEAIKPSETRELPESPDPSIVIRALSGDFTTQTDFNDEESAEAEDLEDTQTIRLFDQLLRQEEADMDCDHDLERLRWTLIHEPWDDEDEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTK0</accession>
    <name>M5FTK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626316.1">
        <property type="nucleotide sequence ID" value="XM_040769006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTK0"/>
    <dbReference type="GeneID" id="63684068"/>
    <dbReference type="HOGENOM" id="CLU_1626986_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067203" evidence="1">
        <location>
            <begin position="19"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="18330" checksum="AEC1F3D0F749315F" modified="2013-05-29" version="1">MLFYQPFLLAALVATTFAAPLHSTRSLNDDSTRSELTERAVVTSETASNSLNGNIPRYSVPRDLAEEDELALFDARDFTDEDAIEWNVAARDVDVEEHELVERSKGVGHALGLRSLDEEEGEGWTIAARDLNFADEDEELAERSRVRERIKHFFQKVGHVIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU03</accession>
    <name>M5FU03_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BAR-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24073</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625862.1">
        <property type="nucleotide sequence ID" value="XM_040773531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU03"/>
    <dbReference type="STRING" id="1858805.M5FU03"/>
    <dbReference type="GeneID" id="63688593"/>
    <dbReference type="HOGENOM" id="CLU_025518_0_0_1"/>
    <dbReference type="OMA" id="QEYDYYN"/>
    <dbReference type="OrthoDB" id="2159336at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="15"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="365"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="423" mass="47050" checksum="618D8C9EC2EC8B7A" modified="2013-05-29" version="1">MKGLTKAIMRTPHMMGARVGLSKKSNDPEFDDYSRKFTAMESATDKLFKDSKTFADAVISLLSSETNFAQHFAGLFEPLGNEYDILGKHPEAQETIRNLPSYQREMEELKEALSPELELIQTRIIGPVKELQGIMKGIRKSITKRDHKLIDYDRFNNSLTKLRDKKEKSLNDEKNLFKLEQDFEVASNEFEFHNTTLKTELPQFMILATRFIDPLFHSFYYMQLNIFYLMLEKINGFASGKYDVSLQPADVATAYEARLGDARDRVEALTITKRAMPTAKMLSMRQGSSPSGTSAGERRAPPSLAAKPSVLAGKPPLRSNSYAAPPPAYQEASFGDSPAAAAASSAGTKRAPPPPPPLKPKPGAPAVKYVTALYDFAAQAEGDLEFRVGDKIELVERTASSEDWWTGKLNGRTGVFPGNYVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU16</accession>
    <name>M5FU16_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628068.1">
        <property type="nucleotide sequence ID" value="XM_040773021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU16"/>
    <dbReference type="GeneID" id="63688083"/>
    <dbReference type="HOGENOM" id="CLU_927563_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33591" checksum="F1CDDFA416C38973" modified="2013-05-29" version="1">MYNVIIVPNGRTVSADDLDGVSTVRANLSNGLALLIEPHSRSCQACRKKRTYCIHEEGFACYTCRASGGCLYNSSQTVEPRRGNTSTPSKRQRPTSPAPRIPYKDYPRLLPNLLRTNTPARTQGEPSPRSPKKRRTDQPRGSSTSASKQKTSTRKSDVVEEPTLPSPDPLSDYDVEEPGAESDDVSIKSSSSTRHETLEAVRSLREVELPLPQLSARLSDTMAFISRAEPVWELTRSHIWPIRELSEWCNAEGRNLRVDVRQEATLAWETFQQGQIAMQDALEKAKKEARVLMDTIAKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU54</accession>
    <name>M5FU54_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623659.1">
        <property type="nucleotide sequence ID" value="XM_040774170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU54"/>
    <dbReference type="GeneID" id="63689232"/>
    <dbReference type="HOGENOM" id="CLU_1970504_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="14335" checksum="57A59EF2312D347B" modified="2013-05-29" version="1">MADVVLALARPGASSPVPEQDDRVLEPGEPMARVHVHRSPSLGTAQVERKHVPPFLRKKLPVPPKLTLAELEALAKWKLQRGAAFYRWKEAWASVPSFRERTTPGLSARAFHRQRKATKKEGLPWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUB6</accession>
    <name>M5FUB6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626696.1">
        <property type="nucleotide sequence ID" value="XM_040771246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUB6"/>
    <dbReference type="STRING" id="1858805.M5FUB6"/>
    <dbReference type="GeneID" id="63686308"/>
    <dbReference type="HOGENOM" id="CLU_019989_0_0_1"/>
    <dbReference type="OMA" id="WEPSAMY"/>
    <dbReference type="OrthoDB" id="2012566at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611">
        <property type="entry name" value="ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611:SF3">
        <property type="entry name" value="FLAVIN MONONUCLEOTIDE HYDROLASE 1, CHLOROPLATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="600" mass="68025" checksum="246A4E6D65EFB010" modified="2013-05-29" version="1">MSTTKTSTPRLTSSSILSRLLNKFLFTSLLSSNAALESVPRTQVIQTGQEGKDIKRIRESQQQTITAVLSDKKSHEDTGAHISDVVLVVKGHMRNASTATDDTAVDTPPVTAPTPPPGYVQPYDTIIFDIGDVLFTWEPAPNRSIPGGTFKLILRSHAFYEYECGRLTEEEFYRSTADRLNVPYEDVQAAFHDARESLVPNPLMPPLIRQLKENHKILAGSNISKPDFDWLHARPGFDWDVFDRIHASYAIGARKPDHSFFRSIIDSEKLDPARVIFIDDKVENVLTAKSLGVAGFVFRDQESAVRTLWALCADPVERGWKWVEENKGRMHSFTGQGKDVEENFTQMLILELTGRADIVNYDKYDRLFHFYQGDKQPTIKEFPYDMDTTSIGLSICPHIKPEMRHDVMNEMLTCLNTDNIIQTYFDRKRPRIDPIVCCNILTLFYSNGRGDEPLLQQTKAWVIDTLKTRAYLGGTTYYHCAETYLFFFSRLLLHSPELCAQYLDLLLIRIRERVGIPSEACGLALRMLLCAQHDLDPGQDFKLLLLAQESDGGWPAGGFYRYPGNGVMIGHRGWVTCVALEAIKRGRERGWSADLKEIIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUD3</accession>
    <name>M5FUD3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628233.1">
        <property type="nucleotide sequence ID" value="XM_040767441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUD3"/>
    <dbReference type="STRING" id="1858805.M5FUD3"/>
    <dbReference type="GeneID" id="63682503"/>
    <dbReference type="HOGENOM" id="CLU_470103_0_0_1"/>
    <dbReference type="OMA" id="EFAVRWK"/>
    <dbReference type="OrthoDB" id="3365224at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="580" mass="62038" checksum="3BF650E9D2B6B604" modified="2013-05-29" version="1">MPPRYPSSPIPPPPHPPTTSTKLRSHLLSLLPLLPKHALFHAKLTIHEVASVPFLDGEFAAKWRFKNAHSVSSAAGGSTGSLLERAGVRKVASYDRLRGASVPVLEADEGEGEGDSGGSSSSSSPRGGRTTPMPGDPPPRPPARPPGASYSEQSYLAPHSHSHPHRPPTTPSSASSYSAPPAGTINFLPQPKGQTQYVPLRRHAAVWSLDVDAAVQMSIGRGVGASEPGTPAFPGTAKEERDREREREREREREREKEPGLLQPCELKLSIIKYLHDWERKDELAREGAVLGSVVLNLAEYVGEGVVTRRYLLRDSKTNATVKLSIEMTQIGGETRYKSPPLQKGQILGSVAGLMSDDHMRRHARSPLLRTASSGSSSSSLYLPPAHLSVLPPAGHKRTPSAQSVPTPQPTHAHAHTPSISVSVHGPSPPSAYSPAFPTALSSSGSGSPLAPSTESIIEALFNPFPSQSTSPSPFTYYKPPTPTPASPPAPPISEEEDSSQGSTGTEEDSPGNNTLGKRRWWRKKGKRPAELDLTGARETQTWAGRTRTAQASFPASTMSGSTVTSGTTRTLPGGKWKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUX4</accession>
    <name>M5FUX4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626237.1">
        <property type="nucleotide sequence ID" value="XM_040773454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUX4"/>
    <dbReference type="GeneID" id="63688516"/>
    <dbReference type="HOGENOM" id="CLU_2096794_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="116" mass="12848" checksum="42CEE5DC49F9AC8B" modified="2013-05-29" version="1">MRHRTRRSSGTSLGPQGSLSHRDRVVVGPYQSRKLFLHPMAAADWLVAIFPRSSATVEVDGANGDFHAQNPMTLPCMGKPNNQRYAAASSPAPAPSVSKFLGVCRRRTKRRQWAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV75</accession>
    <name>M5FV75_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_117746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626407.1">
        <property type="nucleotide sequence ID" value="XM_040770445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV75"/>
    <dbReference type="STRING" id="1858805.M5FV75"/>
    <dbReference type="GeneID" id="63685507"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_4_1"/>
    <dbReference type="OMA" id="YPGLGNK"/>
    <dbReference type="OrthoDB" id="9997102at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="16"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="349" mass="37556" checksum="D77F6002082B81EA" modified="2013-05-29" version="1">MSAWPSIAPPRAPSPTKTILVIGATGKQGSGMVSSLVSANRLAKPQQPLPYRVLALTRTPHKNEGMKQLPGVEVVQGDLNDEAGMEAIFSGEGMGGIWGVFMCLAFPGLGKPADSELAQGKLAANLALKYQVQHFIYASSEQGGDSESGPSPSHVAKMVIEQHIRELGRQYPGFRWTILRPAFFYENFDGVLGAVSETLLASSVQKGTKIQMVASEDVGPVARAVFEAGEEYMGKSMTVCGDCLSPQEVNAVHKKVTGRPLSRIPGFIGSALYGMNAHAKNLVMHMERVHQLRLQDPAGYTANGDAAKRAYPGMLTFESWMLSKGKVRGGKREKGWNNLTINELVKGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVN1</accession>
    <name>M5FVN1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_119510</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624304.1">
        <property type="nucleotide sequence ID" value="XM_040770804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVN1"/>
    <dbReference type="STRING" id="1858805.M5FVN1"/>
    <dbReference type="GeneID" id="63685866"/>
    <dbReference type="HOGENOM" id="CLU_034302_6_1_1"/>
    <dbReference type="OMA" id="VMYTYMM"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="286" mass="32733" checksum="197E6201DB498779" modified="2013-05-29" version="1">MAGRARSTGAETAESHRVQFSVVQYYLVAYNVLSCLAWAWILGRCLYHEISGYWEPLSVGLKAQMMSLLRAMNPTAPSLFTPAVFNYLLPKWLHPLTNQASTMYAEVGLEVKIIQTFALLEVVHAMLGLVKSSLATTIMQVASRLILVWGIADHYDQAKENPLYASMVFAWSITEVIRYSWYALNLCDLKISWLTWIRYTFFYVLYPVGAGSEAFVMFSTLPPIVATAQSPRPILEMWMEQPSAFVRLFLFLGWWPSLYVLYNHMRKQRRKVLGSFKAKGRSLKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVQ3</accession>
    <name>M5FVQ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627316.1">
        <property type="nucleotide sequence ID" value="XM_040770372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVQ3"/>
    <dbReference type="STRING" id="1858805.M5FVQ3"/>
    <dbReference type="GeneID" id="63685434"/>
    <dbReference type="HOGENOM" id="CLU_593147_0_0_1"/>
    <dbReference type="OrthoDB" id="3133596at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="51"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="461" mass="50590" checksum="79F889CD11B9C32E" modified="2013-05-29" version="1">MSAKPANTSPPRSTSSRRNVPYATPHGESKPNSRTPSAAKSALRAVDGKKCLITRQQDSAIELCHILRRSLRDEQLAFFRDIGILLNIHSRGNLLSLDASLHLSFDRNEWTIVPTEMTLSWMLNYIEDPGEDGMTFEGMWSSSHIANSSQWQTYEFASFPTFKRCFALLVEEPAEHLFVVPRISYALYLPSEGPSPFLQTNYRVHPYNSDVRPYPMKPFKHHGHPLLILMAAAMRYAHNKLNLTGSQQQRLDNMVKVLKEWLKKKAVDAPPEKLPQEDQGSNPDDDGPDKKDEVPPPPDPLVAALAQINTLTGYKGKSAPAEKRPAPGESGDEPPSKKRVSSNDLVSGVEPPSDIVAAPDPLPDTDAIVEMLLSMGDLSAERRSSRVESTFDGSEFSVEEDPGSLSDGDESPPSPPSSRNPAAIRSASTKLVAVPACVSPDRVLSWVESSSGAMDPIAESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY4</accession>
    <name>M5FVY4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_79710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628913.1">
        <property type="nucleotide sequence ID" value="XM_040776411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY4"/>
    <dbReference type="STRING" id="1858805.M5FVY4"/>
    <dbReference type="GeneID" id="63691473"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_4_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="23550" checksum="916D583D12416CFC" modified="2013-05-29" version="1">MAPITPGSLVVVTGITGYIGSHVGLAALQAGYRVRGTVRDTKKAEELGAKYNELGVDAGEDKFEVVIVDDLTDQAQFEKAFVGAEGIVHVALPGHTATWIDQATTSILSVFRAAAKESSVKRVVLTSSSVTCITPGQNGDHTLNDEDWNDDAVDAFKRMSEEERGNPKNRTAMYCAAKTIAEQEAWKWMADNKGWQRSSPVHPVLDGPGFLAIVGPGPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWA9</accession>
    <name>M5FWA9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione S-transferase C-terminal-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_58812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624569.1">
        <property type="nucleotide sequence ID" value="XM_040775518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWA9"/>
    <dbReference type="STRING" id="1858805.M5FWA9"/>
    <dbReference type="GeneID" id="63690580"/>
    <dbReference type="HOGENOM" id="CLU_011226_14_2_1"/>
    <dbReference type="OMA" id="WDENWKG"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000039">
        <property type="entry name" value="Glutathione S-transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF3">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR URE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="95"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="222" mass="25556" checksum="4809E95A01B223C4" modified="2013-05-29" version="1">MSHGKQFTLYAHRTAVNGYKVAIVLSELGLEYEMIYLDFDKKEHKAPEFVKYNPNGRIPALVDHANNDFVLWESNAILLYLVHRYDKGHNISAFTDADKALQDQWLFFQASGQGPYYGQWAWFVSAPEKIPLAIERYKKETERVLSVLDTVLTGQKWLVGDKMTIADISFIPWNDLAFHRILGPDYPLGETFPAMFKWHTAMMSHPAVKTNMEKRAELLKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWC0</accession>
    <name>M5FWC0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_90066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626887.1">
        <property type="nucleotide sequence ID" value="XM_040776942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWC0"/>
    <dbReference type="GeneID" id="63692004"/>
    <dbReference type="HOGENOM" id="CLU_021555_3_2_1"/>
    <dbReference type="OMA" id="CISAWST"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF15">
        <property type="entry name" value="NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="56691" checksum="69EE82C9967D7D0C" modified="2013-05-29" version="1">MFTKEKLSYWAKRLKVPADEDARYKTDIWCNRDLIPIPKERRTWGIWGYCGYWTVSGSCVSAWTIGSTMLSYGLNAQQAMACIAVGGVITGLLAIGCGWMGEVHHIGFTVSSRFSYGMRGAYIPVIIRYLPTSQLAKNDFIGFIIALILFGFLMQKPFIASFTTFVGTMFGMLIWAVHANGGSAGPLFKSAATTDNVGWAIMYGITAMIGSWGAGCLGQSDWTRYANRRGAPTLSQLIFAPIFITITALIGVVVTSCTVEILGLETIIWNPIDLLPVIQQFYGNSSGARAAVFFASIGLVLSQLAITVVLNSVSCGMDMAGLAPRWLNIRRGGYLMIIVGVLVQPWTLVATAQRFLTVLSGFRVFMAPMTGVMLADYFVVRQRKLKLNDLYRGDSTSIYWYNRGFNWRGFSAFGLGSVFLFPGFIAAGGGYSIPIAWLRLFNLTFILGTVFSFIAFLIINYFFPPPGLGEESPFYLDGADDYATKGDWKAEIGAKDEESASEEKAAETEISEFPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWM9</accession>
    <name>M5FWM9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_117196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627691.1">
        <property type="nucleotide sequence ID" value="XM_040770336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWM9"/>
    <dbReference type="STRING" id="1858805.M5FWM9"/>
    <dbReference type="GeneID" id="63685398"/>
    <dbReference type="HOGENOM" id="CLU_014668_0_0_1"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007130">
        <property type="term" value="P:synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="7">
        <location>
            <begin position="87"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="527"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="724"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="793"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="724"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="863" mass="97131" checksum="AA347970017EA762" modified="2013-05-29" version="1">MNTIYCDGGRQHVGGTSTTSKWVTQYHFGARAAKFCVTQIGSSHVHVLLRSVYQPLLSGVWLTIALSPVTPPFHFHMLSQARTITQEQSVQTVKQLLSAWFNCIAWIRNLLPADHFVDGSITNDPLSQSHNTSSLSRSNRVQLKTVKRGHSGAGDRLLDYLENGIFDALEKQYLRSFMFVVYLDPNDPNNIIESFTFSFTYHTIPGTNTVVPIMNGLHSDKEHILIARRSNALQAVTKGKVPTLREVRESVQTLVKRLIMMTQSMDELPPQRYVTFKLFYVDGTPDDYEPPFFRAADAEKDRFFFATHNAIERPDKIAIGALNTSFHGVTLTFASVCNTLPKQHDDLPFDTDIPVQVLSTQQRQAHQLQEMKAQQGDSLSRRVIWEAEGRAYTHDSLCDGDGEPDPDFDGLAPDLSEEQPVGFRDEDGRVGPMQSSDTAMDLEEAAHAGSPENDADFENQYKAGISSPYKIQILSIPQIRLRHKSMSDPTQRLRSRLQGMGGLIGMSETMLTAGINTLNLNAITFDEGSGDIDMGNGDYSSVNAMQEPRSERSLRPRGPKTGPPNSTSHPQRPNADISNEDERNCCCGIRLRVKKDIEDTSNWCQCEGPCEKWYHLWCIGYNDVEEFHHDYPELRPNTKPWLCFECCFRENSLVALLSEDEKQEKIADFKDLALFRLVLKLFIQPNNLPDGPSALRKRLGCLTSAGNLIWQRLEKEGLIIREGLDGADGGHEDSRTNATRPKPKSKQKARRAGPVKYVVSRHQAKKGCTKYFDKSYKLEEQIMGLKELRRGVRTEKKRKNTSDDETDGEPAAGSVDSQTQLEENVVPLFSLSTNTRRQEKELRYRPNKKLKVSLAQHPIGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN5</accession>
    <name>M5FWN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624739.1">
        <property type="nucleotide sequence ID" value="XM_040769218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN5"/>
    <dbReference type="STRING" id="1858805.M5FWN5"/>
    <dbReference type="GeneID" id="63684280"/>
    <dbReference type="HOGENOM" id="CLU_1081916_0_0_1"/>
    <dbReference type="OrthoDB" id="5362978at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="29542" checksum="FBBBDDD4EFDCE2BC" modified="2013-05-29" version="1">MSAVILHPTDWLAELRSHIAPLHEVPNSDHDPFYSGWPMNYYEGLAQIRKVVLGNAVESFWYALINVVLTHLFPSDSGFLVLPQPVPARDHREATDSMIFWIRMVASSPKREGRGYVIVVWEAKPEWAYGSFSGEMEADNQMRTRLLDVSRTWDQEAPLIIGISSFGPRFHVYTKFRGKHIQPPRRSNDAMYESEDVWPGSHHQFIIHRESGHKALELVRDICLEILQHEMGPVVLEHVHALIQSLKASEGDERERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWR0</accession>
    <name>M5FWR0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_79201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629285.1">
        <property type="nucleotide sequence ID" value="XM_040776382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWR0"/>
    <dbReference type="STRING" id="1858805.M5FWR0"/>
    <dbReference type="ESTHER" id="dacsp-m5fwr0">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63691444"/>
    <dbReference type="HOGENOM" id="CLU_006586_15_2_1"/>
    <dbReference type="OMA" id="FECPAAR"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140963" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="28"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="365"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="521" mass="54872" checksum="A903305E2CCB55E0" modified="2013-05-29" version="1">MLLQLAFSLGVLHIGAVGCSPIEPQAGTLVDTAQGPVQGMLVSAGVRQWLGIPFAASTGGSLRFEPPQPAPSRFSTFSATQFGDSCPAILSAEFLELLGMLQQQESVPFGEDCLSLNIWSPATTRPQGGAILLWVYGGSGQFGTSNTPYYNGQTFVANFDDIVIVTINYRLNIFGGPNAPQQTLDLSMLDMEAAIQWVYANIAAFGGDPERITLFGESAGAIAVDAYGFIHPDDTIVKGIIAESGTASLAGNSSTDSSAYSAADSPWNTVASALGCGTTDDAAQFACMQSVPWQDLLNEVISSGQTFGGGSTGLVGDVSALSSEGKFLKVPFLVGNNANEGDIFVVEMEEENLNTTIPIVGTVISDAITILLATCPASKEAGDRVDAGVPTWRYMFEGAYPDLTNNNPNLRAYHGEEIALVFGTYNYSTFPYPPTANEIELSSWIQGAWVAFARDPVHGLTNYGWPEYGSSVLWPVAALGNPGNPGGATYEAAVTFDLTCDVLDTVEAIVENVVALLGDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWW5</accession>
    <name>M5FWW5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629370.1">
        <property type="nucleotide sequence ID" value="XM_040772680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWW5"/>
    <dbReference type="GeneID" id="63687742"/>
    <dbReference type="HOGENOM" id="CLU_2066946_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="13077" checksum="68B2DDA92BD8E0FB" modified="2013-05-29" version="1" fragment="single">MSMVGSHAMAAARALVNRETGIDILGPKPKPDKATPDKTTPKPSKRKSGKTNTNKNKSKPDQGNPDKTKPGKVHPDKETDEEYQDKVNSNLRLRLFQIREVDENTQLVDMPEGGRGTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYB0</accession>
    <name>M5FYB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_57607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625439.1">
        <property type="nucleotide sequence ID" value="XM_040775457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYB0"/>
    <dbReference type="STRING" id="1858805.M5FYB0"/>
    <dbReference type="GeneID" id="63690519"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="FINGSHF"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="284" mass="30574" checksum="F130CAC374657D0E" modified="2013-05-29" version="1">MSLQCLSHAIPDNIISVTGASSGFGRAMTELLLKRGEVVIATLRKPEALDDLQYGRDRLLVLKLDVSKPADVDAAFSKAKEVFGRIDVVYSNAAFGVLGEFETATRSSEARQMFDVDFWGAADVSRAAIEFFREVNGPSVGGTLLVMSSMAANYGAPALSYYSAAKQALEGAIEGLEKELVPAWNIRVCLIVSGSFKTRGSQNVITLPPHPAYKDSSSMLTRQYVSSAPGADVDSAVQIIYDLVKEPNLPMRFPLGMDGVQSMLGKANALKTDADKYSTWSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ82</accession>
    <name>M5FZ82_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_56843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625779.1">
        <property type="nucleotide sequence ID" value="XM_040775401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ82"/>
    <dbReference type="STRING" id="1858805.M5FZ82"/>
    <dbReference type="GeneID" id="63690463"/>
    <dbReference type="HOGENOM" id="CLU_002173_9_3_1"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="62"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="399" mass="45913" checksum="5D3BF0B67AB910C0" modified="2013-05-29" version="1">MTILRHIPFTIPFDDRVFLFRQCVKQDKTSTAHADQSASFHPKPVRRHNLSEDGFDHFCSAETMLLKGRIRITFIDQDGHQEQGLDGGGLWKEFIVTLLEESFNPERGLWTKNEQEELYPFPQMFAREARQLKWYKFIGRMLGKALYDNILIDTVFATFFLAKWVGESGSLDSLASLDPYLHRALVALKQWESDDCLDPDTRFDIVDLDMGQPITTELVPNGSNVPVTKENRMKYIELVCKHRLDDQISEQTQAFLAGLRDLIELKWLKIFDASELQLLLSGVDRDVDVDDWMRNTAYEGGFSATDPCIHMFWTTVRALDRNEKRLLLRFVTSCSRPPLLGFGELKPKFTIRCASNDQNRLPTAATCFSTLKLPRYKEQEVMRNKLVQAITANAGFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZH3</accession>
    <name>M5FZH3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623800.1">
        <property type="nucleotide sequence ID" value="XM_040774129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZH3"/>
    <dbReference type="GeneID" id="63689191"/>
    <dbReference type="HOGENOM" id="CLU_647267_0_0_1"/>
    <dbReference type="OrthoDB" id="3356373at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46854" checksum="9DAC09D9E9F18F6B" modified="2013-05-29" version="1">MSFPSSHGPRLPLELLLYHIVDILSLPPHPLSYLLPKDQQHALITLSLTCHRLHTYCMPLLYSRICIESAQRLRRLRRARPADLGKITALFLDFEHLEDEVLLPIPAQDADIVGNSYRTFAGFSSRAALYYEVSEQLSFLISACRPSLQRLAFGSRGRPHPPWVSMDPMEERAVEHFASQANYAIASTLPGLRELICVRQNMEIGDYLGLGRSGGQRRWEKLERLAVYGTLSYNAHDAPPILPALECFCALHPFPSLALLSQAVTTSPNLRELSLFNVAIPVSEQTPSVRSAYTDLDRILEALGTVGPAKATQLPVVSNAGAAGTRTLRSEADHEADTFTPPAPSPSASTDEKPETPHRKQPVHVTRLSLPPVYDPHRPEDRRERTSLAARLGREGLLWSWRGEESGAGFEGVGVGVGSEARVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZQ1</accession>
    <name>M5FZQ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_22522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628262.1">
        <property type="nucleotide sequence ID" value="XM_040772844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZQ1"/>
    <dbReference type="STRING" id="1858805.M5FZQ1"/>
    <dbReference type="GeneID" id="63687906"/>
    <dbReference type="HOGENOM" id="CLU_023194_3_1_1"/>
    <dbReference type="OMA" id="IWVGMDE"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="3">
        <location>
            <begin position="148"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="39049" checksum="744E1D27CC123E3E" modified="2013-05-29" version="1">MAPIGLALIGGGIFIQEAHLPAILSLPPSTVHIVALYSRTLASATAAVEECSNFGLGTPAVYADDTPNDLSALLKREDVQAVIVAVPIPNTGEVVMRCLEAGKHVLSEKPVGKDVAEGIELIKKYETLYKPKGLIWRVAENWEVEPTFRFIKSSISAGKIGAIQTFSLTSISYMPPSNKWLGTPWRAKPTYQGGFLLDGGVHQAAFLRTVLPSPTVSLCGYATLQNEHLAPHDCIHAALKCADGAQGFFSLNAGASGWEGRGGGTMILGKEGSVEVQFFEKEGKQWIRAVLRAGKKGEQKEETFESPSCGVAEEQKFFFEAANGKKENDFGNPRGTLEDVALIQAALTSEGNKIEFSQLIPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR8</accession>
    <name>M5FZR8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628901.1">
        <property type="nucleotide sequence ID" value="XM_040772783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR8"/>
    <dbReference type="GeneID" id="63687845"/>
    <dbReference type="HOGENOM" id="CLU_2108930_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067480" evidence="2">
        <location>
            <begin position="22"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="115" mass="12310" checksum="39EEDA36D82E3EFF" modified="2013-05-29" version="1">MPIVSTILMALFAFMLASINATPILPRNEHAPAPDAWCGGHPCGGYKRDALAETNTFGPSTPILVRHESVSAPHADAWCGGRQCEEYKRLEHLESETSDPSGEITYCGGAPCPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0J4</accession>
    <name>M5G0J4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629156.1">
        <property type="nucleotide sequence ID" value="XM_040768427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0J4"/>
    <dbReference type="GeneID" id="63683489"/>
    <dbReference type="HOGENOM" id="CLU_1045925_0_0_1"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="266" mass="30396" checksum="892F09E49C91C147" modified="2013-05-29" version="1">MPSKKKVDKRPQDEKSDIDHPPSKTLHSDTDSARQAQVQVWLKQLKLWVRFARLANISDGADTTETEDTSVDHLPQVTMGRLDGFSPELRQTAGEIVRAVERDPAVLPIELRQLYGFPPADTEVLEYLLLPKEMDECQTAILCFLKTLYDELASLIEQKGGKQEYADMADWFRGYMATWTHMKEPSSTRRQFFKSVVEKSKQMWQEMNQSPHLSARERSCKSRMIDSFEKFSARLQPDKSSRKIAAPGIGLRIGPPTQYCAGFRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G111</accession>
    <name>M5G111_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629323.1">
        <property type="nucleotide sequence ID" value="XM_040771129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G111"/>
    <dbReference type="GeneID" id="63686191"/>
    <dbReference type="HOGENOM" id="CLU_1786783_0_0_1"/>
    <dbReference type="OrthoDB" id="3419757at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="19476" checksum="B3FC813E8D52EA52" modified="2013-05-29" version="1">MAATRMQHNHLYIQVLDWHKVGAYRICGLQIHRDGSIRAQVEYDNGKPYWGWIHSNDDMSTIGAVVLFELANLGSKYRLYVEKLKAFKADTEKTAEDILIAFLDELKSLELLGASGQTLMTEVKAEAGRRGFANSTDIVRSEHFVTVQCGISGLVRDESDKALVVRWAVSMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G112</accession>
    <name>M5G112_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_77730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630830.1">
        <property type="nucleotide sequence ID" value="XM_040776286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G112"/>
    <dbReference type="STRING" id="1858805.M5G112"/>
    <dbReference type="GeneID" id="63691348"/>
    <dbReference type="HOGENOM" id="CLU_026578_1_0_1"/>
    <dbReference type="OMA" id="MYGVYTI"/>
    <dbReference type="OrthoDB" id="1436450at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="42873" checksum="B562979DF39DB951" modified="2013-05-29" version="1">MSADRANYAFGIALLVIVVFEWTFSNFLTQHLFITGYNKPFLITYLNTSTFSLYLLPQLGKLWWERKAKGDEARGDYSVLAPEAPVRGRRVSLERVRSAHSLSPPHLPPPPQEGILPPLTVREHASLGAIFCVLWFAANWSVNASLEYTSVASSTILASMSGFFTLVIGRMFGVELFTLAKLGAVIASFSGILLVSLSDGTSDKPSTSAYVVLGDMLALLSALFYALYVLFLKIRAQHESRLNAQLFFGFVGLFNTFGLWPIAIVLHLTGIEPFALPTDGMAWGALGLNMFITLSSDYLYVLAMLKTTPLVVTIGLSLTIPLAVLGDMWMGHWATLQTVFGAVLVLFAFSAVGYDSAKEVRALELPREDLETTYGAVTPPGTRSPVVETPAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Z0</accession>
    <name>M5G1Z0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L22e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_21947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629132.1">
        <property type="nucleotide sequence ID" value="XM_040772620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Z0"/>
    <dbReference type="STRING" id="1858805.M5G1Z0"/>
    <dbReference type="GeneID" id="63687682"/>
    <dbReference type="HOGENOM" id="CLU_105624_0_0_1"/>
    <dbReference type="OMA" id="YQLRFYN"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="13602" checksum="26A38DA7F2D6F97B" modified="2013-05-29" version="1">MAKAAKPVVSKHKFVIDYSKPAGDGVFDGGLYEKFLRDRIKVEGKPGQLGESIKISKEGTNKLAVQASIPFSKRYLKYLTKKFLKKNQLRDWIRVVATEKDRYELRFYNIAEDAEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G213</accession>
    <name>M5G213_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="17">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_24774</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 Fe(3+)-[Dph3] + NADH = 2 Fe(2+)-[Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71231"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:71232"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 17">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="17"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624700.1">
        <property type="nucleotide sequence ID" value="XM_040773846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G213"/>
    <dbReference type="STRING" id="1858805.M5G213"/>
    <dbReference type="GeneID" id="63688908"/>
    <dbReference type="HOGENOM" id="CLU_003827_9_0_1"/>
    <dbReference type="OMA" id="VQIFMCG"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 17" id="KW-0274">FAD</keyword>
    <keyword evidence="5 16 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11 17" id="KW-0520">NAD</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="19">
        <location>
            <begin position="40"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJT97802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="283" mass="31306" checksum="024089C90DF5993A" modified="2013-05-29" version="1">MALPLVPIALLVVGAVLLLIYAQQKGLLGRKRGVPVLDPKEWKEFPLVEKIPVSPNTALYRFALPHADDILGLPIGNHISISAEINGKVVTRAYTPTSSDDDLGHFDLMIKTYEMGAISKWISLLKPGQKVRIKGPRGQFKYHASLSRELGMIAGGTGITPMLQIIRAALKTHLDLTKLSLIYANVNHEDILLKKELDELAQAHKHRFKVYYVLNNPPEGWTGGVGFVSKQMIHEHLPPTDHNIKILMCGPAPMIGAMKKHLHELGYPAPNTISKLADQVFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G249</accession>
    <name>M5G249_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624735.1">
        <property type="nucleotide sequence ID" value="XM_040773854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G249"/>
    <dbReference type="STRING" id="1858805.M5G249"/>
    <dbReference type="GeneID" id="63688916"/>
    <dbReference type="HOGENOM" id="CLU_026393_1_0_1"/>
    <dbReference type="OMA" id="EHEMSIC"/>
    <dbReference type="OrthoDB" id="3345970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="641" mass="71581" checksum="4003BE8CE0479BAF" modified="2013-05-29" version="1">MAPGRSSEDLDNEALLPGPSPSTYKKWRVFPTSRFGRIALLVVVTVALTGLTLHAVFRPDYARGVRTVVDWVNSSTPENEGMDGRPNTALPGEATGAPDSSGGGIMNAGGGATDDGYEYGAHAKGHEWTMEELREMVKGTKGYYVRDWSLGLGWNNMRYIIEASLLHAQLLNRTLVLPSFIYARGCEFSYDVCAAYGPQVDRFREVGWRRVKRGETSVERSIGMRDDPDAGRVGWRIPIEYMLDLPHFRSAHPVVLVSEYLTLHGLDPAIEWKSGMWGRGSYQKDNTFALIHNQDYDPPAILRVDKLLPESQTYIGNWTQKGELVQARIQLKKGTSEFGVMEWEDVKNDLRGADGIDVNDDESLVQSLREGGLSVLYTFQGSRGIDLIKHVTEPIRQVAPTTMLRGLVDDWDNITDEVLVLEGEVHLWRKPGSLRFTTPAGRSEFEQIVLHSMQPHPRVREIGELVARHVFELVQGRMWFAGHLRRGDFVQLGWALEHDIGPHLKMLTDAFEKGKETLRQIKENGDAHAAPVPGVQLNTSVWSLELPQQGDPFFLATDERGAEELAYCRAHGALLTPDIISFADRRLYGWELLFSDIVMLVEQVIMSQSAFFYGYGASSVAGGTLNQRAARGMDPRTGVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G265</accession>
    <name>M5G265_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UPF0220-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0220 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629207.1">
        <property type="nucleotide sequence ID" value="XM_040772634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G265"/>
    <dbReference type="STRING" id="1858805.M5G265"/>
    <dbReference type="GeneID" id="63687696"/>
    <dbReference type="HOGENOM" id="CLU_096876_0_1_1"/>
    <dbReference type="OMA" id="VHITFVD"/>
    <dbReference type="OrthoDB" id="268928at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007919">
        <property type="entry name" value="UPF0220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13180">
        <property type="entry name" value="SMALL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05255">
        <property type="entry name" value="UPF0220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="188" mass="20670" checksum="556D70A9F4B58832" modified="2013-05-29" version="1">MSLPRSAYDPRRVCVIPFPITPFLRHKRAIGVYAAGALFAMAQWLFFDAAILSAHAKPPPDAPYDEVPVHVTFVDWIPGICSTLGMLVVNLINRERLLGEGGIGGGWGEGGVVWRARLYLFLGFALMAGGLAGSVTILVLKYIIPDYPDKYEYYGVANVAQNVCIMFSAVALWLAQNTQGEYEYRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G276</accession>
    <name>M5G276_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plant senescence-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_51562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G276"/>
    <dbReference type="STRING" id="1858805.M5G276"/>
    <dbReference type="HOGENOM" id="CLU_112614_2_1_1"/>
    <dbReference type="OMA" id="CCEAMIG"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052997">
        <property type="entry name" value="RRT15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33047">
        <property type="entry name" value="PROTEIN TAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33047:SF8">
        <property type="entry name" value="REGULATOR OF RDNA TRANSCRIPTION PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="135" mass="14907" checksum="8C16A7785A5F8F84" modified="2013-05-29" version="1" fragment="single">EFCFGMIGRADIEGSKSNVAMNAWLPQASSFSVNPCGNFSGTSSLKLRGTKGSIGHTFMVCIHTENQNQGDFYPFILLEISVLNESPLGHLRYLLTDVPPQPNSPPDNVFNPEQPAKDFEAKRWDFRPSSASLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G4</accession>
    <name>M5G2G4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629299.1">
        <property type="nucleotide sequence ID" value="XM_040771127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G4"/>
    <dbReference type="GeneID" id="63686189"/>
    <dbReference type="HOGENOM" id="CLU_1137971_0_0_1"/>
    <dbReference type="OrthoDB" id="2873829at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="27282" checksum="D82F60FDA9A0182A" modified="2013-05-29" version="1">MPWNTLHTMKDMDAAQQHRHTRLDTGDEVIPITNDSDNDVFTAPAMASLGKPVHIESHGNHSETKTKTLLNDNIPVLCWAVGHVAALKFQQEDDKWPDQVYLSVDPIVKSNSDCAAQICNMYSKPKQGGSLIPFGTVIASKFQTPFSPLKNKDAQPLEFTAVYDAMHGMKPKKDLRQYSASHLKKGDVVLSKMHIKKRFDCTSCNLGSPKKDWSYTVGFTLHAVYVIEVGSIPKDDDTEVEYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2J2</accession>
    <name>M5G2J2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631335.1">
        <property type="nucleotide sequence ID" value="XM_040768098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2J2"/>
    <dbReference type="GeneID" id="63683160"/>
    <dbReference type="HOGENOM" id="CLU_1057767_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="30236" checksum="608D3CB9B4D8AAF3" modified="2013-05-29" version="1">MKFSAEYYDDAFEVARVDEGLVHPNASLNPLKRLARQCMEKAKLPGAWQESAAVRVQNASDEDEDEDMDAVEDLVDDSDTDREDEDEMTEWNSNPYALTEEEYQLRLKQLKHSEDEAWERARQILAEVRAQYKDTPDAEGISEDEDADETDADSDIEYEHEQLDDSVSEADYFFGETQMDKEFDMLLTVMRPFPHPKKLALALKGLSQVRDPFSLRRLPGHIRRRHANMSPPHISCMPFPYAVLSDYTVWPDGVCPAFRLGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Y2</accession>
    <name>M5G2Y2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629953.1">
        <property type="nucleotide sequence ID" value="XM_040769981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Y2"/>
    <dbReference type="GeneID" id="63685043"/>
    <dbReference type="HOGENOM" id="CLU_924447_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="301" mass="33868" checksum="67E1BF534630F357" modified="2013-05-29" version="1">MDFQDIAKIERCHEELQSQHDRLLDDIKEGREELLHNAHKTKKDIYRMKQILGQFLHAKHAVALINRGELPGLGALVTPSKAEQSTRSPAEYIQSPITAESRGSEDRDFLRDSTTGPSSPHQRDTTIDNNSQSVEHTPNPTENGNDVDPMPVQVPVRLTIPETRTVPDNFEKKRRHEEDEALTVPERAEKKKKHGHGEDEGAPTVPERAEKKNHRHGEALTVPERVEKKKKHRHGDNGAEHSREVHKKNQKPRHAERDAANTASTAHATASPHGREKSSSKQTGPKAEPQDITLVSRDIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G362</accession>
    <name>M5G362_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_109046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627204.1">
        <property type="nucleotide sequence ID" value="XM_040768796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G362"/>
    <dbReference type="STRING" id="1858805.M5G362"/>
    <dbReference type="GeneID" id="63683858"/>
    <dbReference type="HOGENOM" id="CLU_2454701_0_0_1"/>
    <dbReference type="OrthoDB" id="2976051at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="4">
        <location>
            <begin position="3"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="89" mass="9853" checksum="E396F5648847A4E8" modified="2013-05-29" version="1">MASVPEQQNGHDCGLWVLAQIMAVMWGVDQTSMTDAEMPQFCCWLHDNMESLPYGPVAPCAPAKEESTLLDLNKTVLELVDLDKAMDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3H6</accession>
    <name>M5G3H6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_118619</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625210.1">
        <property type="nucleotide sequence ID" value="XM_040770624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3H6"/>
    <dbReference type="STRING" id="1858805.M5G3H6"/>
    <dbReference type="GeneID" id="63685686"/>
    <dbReference type="HOGENOM" id="CLU_574969_0_0_1"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067444" evidence="5">
        <location>
            <begin position="20"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="6">
        <location>
            <begin position="59"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="43066" checksum="11596DE814100C7B" modified="2013-05-29" version="1">MLAHSLSLGALALASVASAQTPNVSLLIDNPFYYDLTRSLNVRSLLPFVSARKGAAFHWGSTYSPPSTAETNWTSEVFLTYFAHMRAENLCNGFPIRCGALRNFPHNTFWHNQLPAWLPGNVTAYDLVHNVIPLHVGTEIKALGWNVTSWDVTNELISDTATYNMTSWECVQNADRWPTVTYDGGSTPLVTNLSFAYATWQTALMSASPETRLSYNDYSTGAQDAKTECVFKLIADLNANASIPYNRMAVGFQSHVGAQPGYFVPKAELEITFARLAALGVESMVTEMDLWIQANDTVNQRYQAAIWGDYLDACLYASNCYEFINWDNRDDTSWILPGDGHGVAIATLFDMYGNPKPVTYEIMARFARYAEGAAEMCATALGTESCTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3W3</accession>
    <name>M5G3W3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UROD/MetE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_80739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627434.1">
        <property type="nucleotide sequence ID" value="XM_040776466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3W3"/>
    <dbReference type="STRING" id="1858805.M5G3W3"/>
    <dbReference type="GeneID" id="63691528"/>
    <dbReference type="HOGENOM" id="CLU_744069_0_0_1"/>
    <dbReference type="OMA" id="NDPRNPW"/>
    <dbReference type="OrthoDB" id="1053771at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="41957" checksum="49C65400A86BEDB7" modified="2013-05-29" version="1">MPIPTEVVGSLPRPTALQHAFAQYDAGIISKDELFQAQDQAAEDSVKRMIQTGETYVTDGEQRTSSFATYPVVDTLGGKGLASTLRAGGQYFAIFADGHHRQLPSLISGPFRYSHYAYDNFKKSKPYSGSHPMKTAVIAPSMLYLLYSLNEEVAGRCLSRIWLTRCKQCEKDIRGCFAAGAQRVSIDFTEGRLAAKNDPRNPWTGAHLLKTFIDLNNKVLDRFTAEERKNIGVHTCPGGDCDSVHSLDVDYHELLPSLFQMNAGYFLIELASEKDKAKVYKEIGKTIRSDANGVKQVAFVGVINPLNPEVETPEHVCEALLEAAKYIPKDQLGATDDCGFSPFSIDVKPKHGSPDFARDVAFQKIANRVKGAKMASEKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4J6</accession>
    <name>M5G4J6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627654.1">
        <property type="nucleotide sequence ID" value="XM_040768743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4J6"/>
    <dbReference type="GeneID" id="63683805"/>
    <dbReference type="HOGENOM" id="CLU_003921_4_0_1"/>
    <dbReference type="OrthoDB" id="3252634at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="200" mass="23447" checksum="A174C726C9294204" modified="2013-05-29" version="1">MHMGRVSPSPPCFSPTPFSVTHHFVALEKLFGLCEPVVTGGGDKIDWACFYTDDDTYKLWAQIHNGMDNANKNLYEDFKTKILKYYPGAVNNKHWYATWDLDNLVHKWQCCIKTKGEFTEFYQDFYSISTWLIKHNWISVLNQQKALLCVLKFLPTESCIWDKMLNRLEQKYNRAVDKPWTMAELKETVEWALGNTMTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4P1</accession>
    <name>M5G4P1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Symplekin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630548.1">
        <property type="nucleotide sequence ID" value="XM_040772270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4P1"/>
    <dbReference type="STRING" id="1858805.M5G4P1"/>
    <dbReference type="GeneID" id="63687332"/>
    <dbReference type="HOGENOM" id="CLU_008962_0_0_1"/>
    <dbReference type="OMA" id="NVRYGIM"/>
    <dbReference type="OrthoDB" id="331600at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022075">
        <property type="entry name" value="Symplekin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12295">
        <property type="entry name" value="Symplekin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="5">
        <location>
            <begin position="113"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Symplekin C-terminal" evidence="6">
        <location>
            <begin position="924"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="565"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="766"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1150"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1179" mass="130671" checksum="A99480068B1A4E36" modified="2013-05-29" version="1">MAHQDDALSAGTPDPLQLLSSALSAPADSAEQGERLVQLRVVLENNRPSLIPIMISNLLPTTAMSVDSVLKRWLLDLVLYALGSQALDYNTRTGVAMEVVSHLAGLLYGTHIPIVKTVISCFSSIYPLIFRAVCQPAGMAAQKQWEIVLAAKDRIFKLLDSPTAPLGIKLCALKFMQRAILVQGRGPTDPRLQNIADPNLSLVPTGHPFISPSQLENEGVELLQKMITLLFKSNVVEIISALVNCFDAFVRLRPALGEVILQTLEVWTPTALAAQSPTSIRSVERSIRILLTHWLRSPHGPPHTARVHQILQKQAERIQQAAAEEDRRQATLKRPAPSEDENPHAAQRLRLDPAAAAGMATLGDLSAFDVSTLPPEMVVDLVIANLALVSEQELMAAVQTVRQAFAAATSSVTSQAQPAGGLTTQEAMASALVSRMEDNDDEDVVMEEEEEEDDEDMEYEPDKLNEQLSLDLPATSAHGVVLEADDEDVLQSLRLANYELPLPKPVDPDSRTKMIQSVLSRLWENGKETELQAPEESDAEDIKAVAGLPAHELWMLTLVRMVTRGSTSSGDDSVSSKSEDDSPPPVRTHPSSDDIRQRLYDFVLSDFPNRIKVATTWLTEEWINDKRHTQDELLPSGHYEKWLRMIVEELTREVDSKDKSLNRFLMDVPVLPPFVFGMMRELCVVEQRMAIGFGVLREIAMSREPLRKQALEIVFDLTTHPVKVTRNAAIITTKRWVQDNRKLESYTRAFASQMLKRLSLGTAVSNDANINGEPPDMDEESKHLNASETETAEPKASPAREKNLEYATSYVPEVPVPPVDRALVQQYLELYFVLCLTSQEMLDEIFDRYPYMDSSVQEAIQDLITNLVKTLGQSNGKLLTLLRTFPAGSETLALRVLNILTETRRPSAPLVALIKAIVAERNLDVRFLMPILSEMEKADILRYLPRIVATLTGQAAEKALVRSVFSSIVTAPPQTFATSSNQPRAKQSELLTPVELMVLLHHIDRDAGLKPTIEAIQLCFSMTDIYRSDVLAAVIQQLVDEPTLPTLFMRTVIMTVQRYKTLTPFVSTTILARLIPKKVWEQPPLWDGFLRCAKMIAPSSYAVLLQLPKAQLRDAVSRDADLRSGLKDFMVKRGGNNRARLVEIFGEDDESGHPNITGHTGSSPAPPTPTLLPNEIGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V2</accession>
    <name>M5G4V2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627784.1">
        <property type="nucleotide sequence ID" value="XM_040768615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V2"/>
    <dbReference type="GeneID" id="63683677"/>
    <dbReference type="HOGENOM" id="CLU_026023_0_0_1"/>
    <dbReference type="OrthoDB" id="2959034at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="395" mass="43359" checksum="2AE546D9FC33249B" modified="2013-05-29" version="1">MKNTQFVPDTPPDAPPEYGTINPGPSQAAAASTQAAGSNSKAPLNARLDTLAGLYTPQPALETAPLPGEPAEQGWVSWADYVTWGGMMQAFKKKQKQDETRATMRSLIHDTLKNLSDPGALEVLHSCQAACRAHALPFEQLIQEDVEGHTPLYWSILAVCHLPSAQGTPRPSYDNGVGNDILELLLSVPLEDRTIADARSALMLNNANSLFQALRTYPTFEKTSYAETVIGLRGPTTPTLPSGSTPGRVSIVQVEEISDTGVGTFRVGWEIPMWCKRVKVARKVTVQWIARGRGWQCSASIKEGHWVIGIKLLKNSASTPITGVLRLGPLDAKEKVELKYQRRKMETKDHTYDIRLDSVLGGATLEYEDSPYLTPEGTLYVQGEFVLEKKDTRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5G8</accession>
    <name>M5G5G8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632395.1">
        <property type="nucleotide sequence ID" value="XM_040771737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5G8"/>
    <dbReference type="GeneID" id="63686799"/>
    <dbReference type="HOGENOM" id="CLU_1461260_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="185" mass="19914" checksum="DEEDB241692DB776" modified="2013-05-29" version="1">MQCFILALSQSMPTQSAGFSAIPLLPIGALLPSCCSPCIHLLYPSPVQAQRSVVSLIIPECGPSIGTALELCARVLVCMRLQPHGAERTTLVLVLARCSKLRAEPRSRVHGVLGNMVGGMVVGRSVQHQASYKKTRLWTALDCALAMSHRNTSFWSCISRSCKAGSCSSGIGVHWDDGIIVERRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G638</accession>
    <name>M5G638_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_105243</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the USE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631068.1">
        <property type="nucleotide sequence ID" value="XM_040768062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G638"/>
    <dbReference type="STRING" id="1858805.M5G638"/>
    <dbReference type="GeneID" id="63683124"/>
    <dbReference type="HOGENOM" id="CLU_083976_0_0_1"/>
    <dbReference type="OMA" id="NATHFSD"/>
    <dbReference type="OrthoDB" id="4506189at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15860">
        <property type="entry name" value="SNARE_USE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019150">
        <property type="entry name" value="Vesicle_transport_protein_Use1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050">
        <property type="entry name" value="USE1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050:SF7">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN USE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09753">
        <property type="entry name" value="Use1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="262" mass="29077" checksum="F74F9A99C2B745FC" modified="2013-05-29" version="1">MQEHDRINLVRLVRRLELPANQPSTSEQDAYTAWLQAKSQLQKVANARSLWKNLTSDGQTLNLDDLDARIDKLEKLAAKSVDEHPAPLPPRTSFLELLPTPKPLLPISILPPPEALSVQTSAAADTTAELTTSEPLESSLLPSEPLLPEFSFLLQPSSKKDKEPEAEYQLNAIQQELADQLAHMGHQLKLNAINFGERLAADVGVVKEAEEKLTGNLDKMKTERGRLRDYSSTARGTTCLVITCILVVIIAWVMMFVVIRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G672</accession>
    <name>M5G672_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_79906</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628229.1">
        <property type="nucleotide sequence ID" value="XM_040776418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G672"/>
    <dbReference type="STRING" id="1858805.M5G672"/>
    <dbReference type="GeneID" id="63691480"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_0_1"/>
    <dbReference type="OMA" id="TRIQINI"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU01332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="452" mass="51014" checksum="8D2843E00CDCF265" modified="2013-05-29" version="1">MFLKFDEWREQYGEIMCLNLAGTRLVVVNSVTAAADILEKQSAVTSGRPRMVMAAEIMCGSLIPAFMTYGLPWRRFRQASHQVFNIRASQAFWPMQEHESELLIRGLFEDQSHLERHLSRLSTSVTWRFLYGGPAIRDPDEDKVKVMNKFVLSVASAAQPGASIVDIFPFLKPLPTWVASWKKNGLEFFKESDVYFMDLFHQAANHKEEASFVNSSLQVAAEFGIPDQEVAWAAGGHFAAGVETTATVLMHFIKAMILYPEACKKGQEQVDQVCGNRIPKFSDRDQLPYVFAMVKEILRWRPPVPCGVPHAATEDLTYGPYLIPKGAIIMDNIWAMSRDPSVFPDYDTYNPDRYLTPDGQVRVSPNPVDEVYVYSHGRRICPGRDIANHSLFIDAAALLWAFDFEKAKGPDGKEITPGTMDFVDNGLAVQPAEYPYHLKPRRANLDELVAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6B4</accession>
    <name>M5G6B4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Auxin efflux carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_48587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631123.1">
        <property type="nucleotide sequence ID" value="XM_040774850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6B4"/>
    <dbReference type="STRING" id="1858805.M5G6B4"/>
    <dbReference type="GeneID" id="63689912"/>
    <dbReference type="HOGENOM" id="CLU_032414_1_0_1"/>
    <dbReference type="OMA" id="VLWFTMM"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF4">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="48228" checksum="A899444D561E6F67" modified="2013-05-29" version="1">MPSPYVLSSLLESFLASLQAALSVLLTLLYGVISSYLGWLSSDTAKEVAQLCIEIFQPALIITEIGQNIAQEGSSVFRLWPIVAWAVAYPVISLLLTYPLLHPLQLPRWSLLAAAFNNTTALPLLLIESLATTGILELIVPDAQKAKRTATTYLLLNAMVNNVLTFAVGKPLLVEKGWEESVMQAEDVSQRLETVIEDIEAEAEAEDASRGYEEESDPRDGEASPLLQKSGTTAGRIESALWTTRGFARLPPPVQKALVAGKELFSPPLIGTILAVAIGLTPALRTAFFAVPKEGGVLRAWVTSSLEDIGRLYSSLQMFVVGSKLYESSSTLTDSSQKEGKPSSWPLAYILFLRFLLIPGLSIGLIYSLATRTTILGTEPLLWFVLMLVPAGPSAINISSIAEVAGAGEETVQQIARFLTLEYAISPLVCLAVVGSLQAAAAAKAIVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6U9</accession>
    <name>M5G6U9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SGNH hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626380.1">
        <property type="nucleotide sequence ID" value="XM_040768907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6U9"/>
    <dbReference type="GeneID" id="63683969"/>
    <dbReference type="HOGENOM" id="CLU_034125_1_0_1"/>
    <dbReference type="OMA" id="HINDVGH"/>
    <dbReference type="OrthoDB" id="544608at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34407">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34407:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52490" checksum="F43640B3ED88CE3B" modified="2013-05-29" version="1">MSSTPSLRRRNGVLALSAAALVTTFLLYLLFHDSPLYPLDKVDLTLRFPTLSSAFRSSSTLPWTRPILPDYCSPGSPEDFWSTRYTEENLSMARSYSGSGTRFRHLVEKAMRGEPVKMGVIGGSVSRGRNSGTLGPYHQRIFRFWNTTFFPHPENWLADGSRPATGSSYFSMCWGEHIPQDVELVFVELSINDYRTTEAASIWETLVRSLLELPTKPTVIAINSFALHGRNGIRNPTLPYLLANPALEASLFGSENGIDPKHINDVGHQMVADFTTHWMRDEICRVMSERDVPPGSVRKVEDNWWTEPIDLGAVPHLRMTEQWRKVNDTIPSLHPTCKSTSSRPPLQPSKGEEWYFEEAPGDKFYWSASKPGAKITFGLDIAEGRVGMFFLRSRKQWLGNVKCWLDDNVKASKLVEGWWNKDESVSDYVALWSNVASGKHNLTCEVQTTTKDPGGGHAFKIIGLATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G767</accession>
    <name>M5G767_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G767"/>
    <dbReference type="GeneID" id="63683993"/>
    <dbReference type="HOGENOM" id="CLU_1948754_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="15292" checksum="4B93B9A2FF5E02C1" modified="2013-05-29" version="1">MEEIWATMELGYSFNPPPPRLQDMLEEDYLTPDIQAFWSPLPLSQLCDPTFRRYESHRALKMRDILDSIFRFLNPSELARICPTNRAFYEAAIPLRWWQINQNGFARLAKMPRPRLRAVSATNHRLKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B0</accession>
    <name>M5G7B0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SEP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_55843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775347.1"/>
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    <dbReference type="AlphaFoldDB" id="M5G7B0"/>
    <dbReference type="STRING" id="1858805.M5G7B0"/>
    <dbReference type="GeneID" id="63690409"/>
    <dbReference type="HOGENOM" id="CLU_029402_4_1_1"/>
    <dbReference type="OMA" id="NKDHTDK"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="119"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="252"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="35580" checksum="2EE2871E7D157D4A" modified="2013-05-29" version="1">MGTGSNPARIPQASGEDGDEGPDQPQQWFTGGDRSGLAVEAPDSARQRRGADRIIRDIIKKAGDTGPNHIEPSIPQEPDAGGFHGGGYTLGSDEVESHFVPDSTGNPNTESEDEFEAQRVVRELTFWQEGFSVDDGPLYRYDDPANAQMLEDINAGHAPPQILNVRIGQPVAVRVSRRTDEHYTPPAPRPFGGSGHRLGAPTPQIAGASAPTSGGILMPGTFPGTSVARPPASPPATTSNPAAAPPSFEVNMDEPNTSVQIRLADGTRLVCRMNHTHTVGDIRRFINASRPENAARAYNIQTTFPTRVLEDESQTIKDAGLLNSVVVQRWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7R5</accession>
    <name>M5G7R5_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7R5"/>
    <dbReference type="STRING" id="1858805.M5G7R5"/>
    <dbReference type="GeneID" id="63682785"/>
    <dbReference type="HOGENOM" id="CLU_020027_11_1_1"/>
    <dbReference type="OMA" id="RKGSMMW"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="19"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="41238" checksum="42EE9ACD9F52EBD4" modified="2013-05-29" version="1">MPLTATLDALILSSTSKPNGIPGLSLNIVRSSQSLYTGAFGLRDPTWPDDPWTEDTVVWMASMTKVVTAVAVLIAVERGLVGLDDDLCQTVPGLTNLINDRSQPCSSGDTPTAPKPITLRHLLTHSTGLVYSAHYPHAQAIERQPKVVGDTRGALGPFWFEPSEEWHYGMGVDCAAVALEELTGQNLGDFMAEHLFLPLGMDSTSFDLTPSMIQRKASPYTRLPNGNVVPNASEYWRFEVTQSSGGGGLWSTAKDYGRFFQMILRGGTAEDGTRIIGQETLRMGMRGQLKEREKESINKMHRKDHSLLGMVFDEDLPTGRSKGTVQWDGSSSCYWWIDREKDVALALCTQITPSDDPEVQKLLKEVDVELYKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7S1</accession>
    <name>M5G7S1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_63005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631693.1">
        <property type="nucleotide sequence ID" value="XM_040775723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7S1"/>
    <dbReference type="STRING" id="1858805.M5G7S1"/>
    <dbReference type="GeneID" id="63690785"/>
    <dbReference type="HOGENOM" id="CLU_000288_57_9_1"/>
    <dbReference type="OMA" id="GPDEVMW"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="295"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="373" mass="39592" checksum="1745FD69AD84BE09" modified="2013-05-29" version="1">MDEDAEREGEEEEPEPTENTSVVSFAQHGKSVFCVSIHPTQPLAVSGGEDDLGYIWSLLTGEVVTKLSGHEDSVVAAEWSADGEMVATGGMDGRVRIWRRVGKDGWGMWEFLTELQGPDEVMWLKWHPRGPVLLAGSNDSTVWLWQLPSGNTMQVFAGHEGPVHTGAFTPDGKRIVTADSAGTLIVWDPRSPTPQFKLSPSSHFPFESGITSLAVNPACTLAVVGGAEGAVRIVNLGKGEVLGGVEGHREGESVEAVEFVELVGAGVSAGGVVVTGATDGKACVWDVGTMRLRVTLEHDDAVTSLHSHPSAPHLLTSASADRTLKTWDTRTGQLVKEHRGHRGPINAASVSADGKWAASAGDEGVCLVWNLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X1</accession>
    <name>M5G7X1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNase I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626765.1">
        <property type="nucleotide sequence ID" value="XM_040767510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7X1"/>
    <dbReference type="STRING" id="1858805.M5G7X1"/>
    <dbReference type="GeneID" id="63682572"/>
    <dbReference type="HOGENOM" id="CLU_005289_1_0_1"/>
    <dbReference type="OMA" id="KGPYQLL"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="152"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="837" mass="92186" checksum="F24BE556CC2D63AF" modified="2013-05-29" version="1">MHESLPHGDLRSLLGYVPPHEPLELRGKNIPYLPRDDTHPFHLVVIAGQECPTHSGIPMGLGATFKDRHKDKDKQSEREASRRDKEKERDRQRHSRNVKADRNTFVAGTMSSWSAILEDWLQNGVGSISGVQPALEQSSDPMNRFRNARGPMDACVSAAVAVESNSEETIDSTHEARLSEPNVAWNISEQGGTATLSAEQARLRAGVKGPYVLLCKERLMGIYIAVFVQRDCRPLLRDYSTGTVAAGLMGGRVGNKGGVGVSVFFADTRLLFINAHLAAHEGKVALRLANLHKIKCELEVDSFLPSDDPRLLSEDVTDRFDYTFVFGDLNFRLDLTRLHADWLISRKEYAQALEFDQLHKLIQEGKVDLQEEPPRFPPTYKYDVRRRSMRDTTVGTRAHVHRALTNTVEPLNETDEHAPGSDQEDDDVDEHEQGSRDFESSSFISSGSAWTGTASTTWTTDADDEEGEDSDGNVVSSSLAVATQAAQKLLGLPAAQKAKTKFMDFIGRPISLAASNRPTFITPETLNAGISDVPKSVSPSPDQKLPVTHSTSTKTHLSRATLEDNEPMTYDSSSKQRVPSWCDRILWKTTLVSGCEHSPVSEHRESMTRSGLRRGYFGNALSSIVLRSGPPLGRQRRNSTSSTTADSRANSSDCDSSRSLHHSPTTSTILFNPNMTASAERRAVKNGDESCALASEPPPAKPFSFDTNIPLTQWHPQNPESRSTAGSVVFPPFVAPIPSPPRLPPVFAVSSLMPTLEPDEPRPSTSTGSSSKWWRHLPGLLTRASAPEPCPVFPSQPEHHRGDVVVLSYKTLDDLQMKTLDGRSDHRPVIGSYAAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8E4</accession>
    <name>M5G8E4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_19624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633380.1">
        <property type="nucleotide sequence ID" value="XM_040771592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8E4"/>
    <dbReference type="STRING" id="1858805.M5G8E4"/>
    <dbReference type="GeneID" id="63686654"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_0_1"/>
    <dbReference type="OMA" id="PRDFKLC"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="42"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="50873" checksum="9E672B33AF28282B" modified="2013-05-29" version="1">MTSSNVIKQTDGPVPFANRLLEGRALDLDVWSIYNALALPADCVNLGQGYMNFPPPAYVKDAAVEALNTTAGNHYSHPKGRPRLRKAISDFYSEQFTNLEGRKLDPETEILVTSGANMGMYSVWAAFLDPGDEVILFEPYFDQYLASVTFNAGKPVYVPLHPPAGYEPSHGPSAASEWTINIPELRAAITPRTKMIIVTTPHNPVGKVFTRRELEQIADVAKEFNLLVMSDEVYDCLTFDGAEHVRIATLPGMWERTVTVGSAGKSFSATGWRIGWLIGPPTIIAPTLAVTTRTVFCTNSPLQEAAAAGLEGAKKRDYFETQRKEYEERLHVLMKAFDKLGMTYVIPQGSYFLLLDISDVEWPEDFPFPQTIQGRGKDFKFCWFVAQAIGVSAIPVSEFYCNEHRHIGEKYARFAFCKDLATLELAGERLQKLKEYLRPRAGNGPTKTALNVVNGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8H5</accession>
    <name>M5G8H5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NTF2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21906</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629049.1">
        <property type="nucleotide sequence ID" value="XM_040772596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8H5"/>
    <dbReference type="STRING" id="1858805.M5G8H5"/>
    <dbReference type="GeneID" id="63687658"/>
    <dbReference type="HOGENOM" id="CLU_022209_2_1_1"/>
    <dbReference type="OMA" id="RPRGNAY"/>
    <dbReference type="OrthoDB" id="339151at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990861">
        <property type="term" value="C:Ubp3-Bre5 deubiquitination complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000003">
        <property type="entry name" value="Nuclear transport factor 2 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="5">
        <location>
            <begin position="33"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="391"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="342"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="448"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="537" mass="55916" checksum="4907F7D0860050BE" modified="2013-05-29" version="1">MSVPAASSTDPTSTVPAPVAGAGAGRPVTPADVGWQFVPQYYTFVNKQPHKLHCFYNRNSTFTHGTEGEDVKHLSGQAQIHDKIVSLGYHDCKVYINSVDAQSSMAGGIIIQVIGEMSNNGEPWKKFAQTFFLAEQPNGYYVLNDIFRFLKEETLAEGDEAEAEAEPSEPAPVEPSQAEPVSGTAQTESAMDAAAQQPQALNGFHPELEKESEPAEDLVHNEPEEPVQVEEAVPPMPEEPAHSIVVAPSAQTAEEPAPTPATVAPVTAPEPAAPKEVPAKVVDVAPPMPEQPAQSTVVAPTPATAPAAPAQPAQPAAPAPPPGPKTWAALASKDSNRWGANVASEARGVSAAPPPSRTPAAPAPSPAPSQGARPPTSQGPPPAAPAPVTTAQCFIKNVTEAVSKTALADVLMNRFGPIKELEIVRSKACAFLEFTSVESAAKAIQASLPTSQGGQGSVRVPVEGGGYVPVHIETRKERGERPVSRPRGGGPGQQGQTGQGEGRGAGNYRGRGEGRGTGRGGERGRGRGQGQNQQQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8H8</accession>
    <name>M5G8H8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631364.1">
        <property type="nucleotide sequence ID" value="XM_040777560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8H8"/>
    <dbReference type="GeneID" id="63692622"/>
    <dbReference type="HOGENOM" id="CLU_2096792_0_0_1"/>
    <dbReference type="OrthoDB" id="3355168at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="116" mass="12549" checksum="E2FB2E4E57CEAE36" modified="2013-05-29" version="1">MDADDNKHPPNNPPQGDTTSEGGFGGDPFSDVNQRGSDKYSRGQLGQGMVEESQAPSAELDEQRNMQVANSGDSLNPYGEIPQEPFTECGTEDQGRETFENARGTAAVQDDRGRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U8</accession>
    <name>M5G8U8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631504.1">
        <property type="nucleotide sequence ID" value="XM_040771876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U8"/>
    <dbReference type="STRING" id="1858805.M5G8U8"/>
    <dbReference type="GeneID" id="63686938"/>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OMA" id="WIISPVP"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="580" mass="64249" checksum="39DA67026496779C" modified="2013-05-29" version="1">MATETWKEVCRRKREEQAASIPTTWLLPSLPPASTLNVLGIPRTCGLLSEKELEITELDDIAQLLESIETGKWSSVQVVTAFAKRACIAHQLTNCLTEIFIDKALERARWLDDYLKTEGKPIGPLHGLPISLKDQFCIKGLDTVMGYAAWVGKTAEEDCTLVSLLLELGAIPYVRTNVPQTLMWGETYNNVYLRTVNPYNRLLTPGGSSGGEGALLALHGSPLGVGTDIGGSVRIPATWCGLYSLRPSYNRLPYQGACNSFEGFEAVPSVLGPMAHSLPALKTFTKAIVNAKPWDWDPEAVRKLWSEREEKLDEHGQGKGLCFGILWDDGLVRVHPPVGRALEMTKAAVEAAGHTVIEWKHYKPLEIRAVLNALFLSDGGTDFVAHTSLPPHELLLTTVFPRPDSPFSHPSLALPPPAENTLLLPHPSIPVHELYSLHVEKRQLAKGFLDAWISSRTRTGTGRPVDALLAPVMATPAPPHGRNAYDFYCEYWNVVDCPCVVLPVTKVNPEVDRKEPAWEWRCQEERVVHELYEPELFRDMPVGIQVIGRKQEEEAVLSIAQLVDDALKSHAVAKQDELES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G913</accession>
    <name>M5G913_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632103.1">
        <property type="nucleotide sequence ID" value="XM_040767801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G913"/>
    <dbReference type="GeneID" id="63682863"/>
    <dbReference type="HOGENOM" id="CLU_1402385_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="22123" checksum="FEFCDF9DC1016648" modified="2013-05-29" version="1">MVEDVKLSNPKCPCWGSRVVTLDANDLPDVEDMINSVAAATPMAMDWEGTIDLTLPPPEPVPITVKLLSSPAQLLLLEVLDKMWPGLRTFNEVTCDITHIRSYTDKATLGHVLWGQAFKEVYGFKGRYKTWYEHAKLLESASLKKLIKQFSKRPGSTWARFWLRAQRKNDGRLKDGEVEMDNQAWWVESDEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G956</accession>
    <name>M5G956_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_16842</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627220.1">
        <property type="nucleotide sequence ID" value="XM_040771233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G956"/>
    <dbReference type="GeneID" id="63686295"/>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OMA" id="GHWNIDP"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="289" mass="31904" checksum="ACD02F0CA6F63CEC" modified="2013-05-29" version="1">MASDPLNQVHNVPMLRNRLRRSQHHPPNAAIDITSHGSDWLWAAFAVFTLTDLGMVAWMWLQPKTQRVLHLLPIVILTASAVTYFTTASDLGSTPITAEFYGNHHQDQAGDPATRAIWYARYIGWTFSLPLLVAEVLLTTGMSATEVASALFMQVVFVVSYLVGALVSTTWKWGYFVIGTAALLYVISYLVGPALVAAGRIGTDVRKVYLCSAPFVAFLLFLYPIAWGLSEGGNVIHPDSEMVFYGVLDLLIQPAFLYAFLYRLKDIDISRFGFAPREAVISEKPAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G963</accession>
    <name>M5G963_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRN6 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632188.1">
        <property type="nucleotide sequence ID" value="XM_040767817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G963"/>
    <dbReference type="STRING" id="1858805.M5G963"/>
    <dbReference type="GeneID" id="63682879"/>
    <dbReference type="HOGENOM" id="CLU_007284_0_0_1"/>
    <dbReference type="OMA" id="TGRTHEW"/>
    <dbReference type="OrthoDB" id="2382881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001179">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001163">
        <property type="term" value="F:RNA polymerase I transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019350">
        <property type="entry name" value="RNA_pol_I-sp_TIF_RRN6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048535">
        <property type="entry name" value="RRN6_beta-prop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221:SF2">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10214">
        <property type="entry name" value="Rrn6_beta-prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRN6 beta-propeller" evidence="2">
        <location>
            <begin position="210"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="926" mass="101931" checksum="2F9F76A64C2389F7" modified="2013-05-29" version="1">MESWTFDLRPKVAADKKSGNRKSDGNKSVESRNALDVGSRGVAALRRSQDGRLQWKFAAEPAAQEERWSTDTASVVKVFPSTAPPVSTAPGLTAHTTADDALQFMYSHYPDVMGFPTDLLENAITADRKVLLRSPFDVYRGNRMAASTTTGKSVGYGYLAWAMGYNMQSLSTKSVFFTIAYLILVIDVTSILHEEESNDLTMMPHATPVKTMDTPIQQVAFKDTTEDAGNNNLLGVRTISGTHIFQVNIRGERPNDVVVESLGELTSVHTSGRRHVDVAIAPSPDLNVVVVDDGGTVHRWSTEQLAAYPQTVEGSLVQDRFHKVAILSNPEQIVLAGCKRLQHLDFRAPLFTSFYDIPEDESDMITNIEVMHNPELICVTSTNTISWLDTRFTGRPLLTWKHRRAWDRGLITQTIGNSSERLVFLWSRSHSLITVYDLLLSQGMIETKTNPYVIPSSVTQEDCAGFAVLPATGQRSGLMFDMSERGSIHTRTLGSPSAQSTHGAVSVHWLDDVQELDEDALKLAEDLGPFAERSNIIVDLREVYETALCRPAQLPLAKDALQEVAQVLQKMPTVVQRHDVPFEHVLTDFDLAFLSVDHHPSRRRSDFLTESSLSRVPAPAEFLLDKVKDMSLSQSATWSCSHAAFIRQTNNDVAEQIDPITYLLKDSVIKQPPLIPPARESAAASMLALDLGLSDTVYFSEVLQSPQSSRREYQDLESATMALSLENPTLPAPVFGHLRPRERPSVDDLQTPRSRLDEPFALHTNSIKASLGASLLLSEWLPGSVPEDYEYVDPYGVAEHEPRQPRTPRQGDRFDHPGIGGASVSQAGPGGPPAIVAVPSSQSLVIPNVQSGAISSTQPFHSRRAFPSSPPPAPFSQLGYPRLAAALPPSSQDLWPSTQQVRGPFGERPEARLARKKAAKKRMAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9H4</accession>
    <name>M5G9H4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_114221</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631794.1">
        <property type="nucleotide sequence ID" value="XM_040769778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9H4"/>
    <dbReference type="STRING" id="1858805.M5G9H4"/>
    <dbReference type="GeneID" id="63684840"/>
    <dbReference type="HOGENOM" id="CLU_000604_57_1_1"/>
    <dbReference type="OMA" id="FNCQLDA"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000702">
        <property type="entry name" value="ABC transporter (Adp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067688" description="ABC transporter domain-containing protein" evidence="14">
        <location>
            <begin position="21"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="853"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="932"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1049"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="387"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="646"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="770"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="770"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU04900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1075" mass="117299" checksum="0539EDF8A67D5A5F" modified="2013-05-29" version="1">MVRALPLALLEAALVLLVEGRGNASTPVRNPYTGRWTGDYPSNDVNALSDFAPTDKCPPCFNCQLPAFSCGQYGECSDYDGQCKCPPGWGGIDCLTPLCDSLADGAERHLRPPGEQCQCKEGWSGINCNVCMNDNACDGFPLAIRVPPEIEDPGEGIANMTCYTGGLTVWENHQMCDVTNRKILDQLGERKPQATFTCAKKDTSCAFQFWVDQEESFYCALDTCKSTLTPGYENGTDQLLYDCDHVKCKCVPGKMLCGEEGSIDLSEFLTEAIKGPATFKCTGNKCSFEEPAMNELIEEVFGDKSITLACYGGECIHYTMVPGYERPEQPDNSVWVALSAAAAGVVFVLASILFWYLGRTSSEGQGAVRLPADEASKLMSEHVPASVHFSNLSYTVNGKQILENITGSVRPGTVMAIMGASGAGKSTLLDILARKQKRGSIGGTTLVNGKEVSNAAFRKVMGFVDQEDCLMPTLTVYETILYSALLRLPRDMSLSAKKYRTLETMQELGILGIKDSRIGESGKRSISGGEKRRVSIACELVTSPSILFLDEPTSGLDAFNAFNVIESLVTLAKDYNRTVIFTIHQPRSNIVALFDQLVLLAKGRMVYSGELTKCQDYFERIGSPCPPGFNIADYLIDLTMRASGDSVRTHPDSSPLLEASDDPNPNLDEEQGFANHTVNAPGQSSSSSTAAAEDAERQVPSQPEESAGAGAGAYIRHKTSQLLSVITATSVTLAPQTLSPELQALVDAYASSDIAAETKAEIAAFSPHVQNGVNGDSDSSNPDSAPGQQDIKSHRRASWPTQFRILSGRAFKNLYRNPWLLTTHYVSAIVIAFACGFFFYQVPNDIPGFQNRLGLFFFALALFGFSCLSSLGLFANERLLFMRERANGYYTSFTYFASKVLFDVLPLRVVPPMVFGGIVYGLVGLVPEVSSFWKFMLALVFFNLTTASVVLLLSIAIADTSVASLCGTLVMLFNLLFAGLLINFQSMPTGLAWIQTVSFFHAAYEALLVNELQWLQLKQNKYGIELDIPSATILSAFGFKANAYWWPDIAILGIEFGVFTILSYLILHYFVKERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC7</accession>
    <name>M5GAC7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anaphase-promoting complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_113825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632673.1">
        <property type="nucleotide sequence ID" value="XM_040769707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC7"/>
    <dbReference type="STRING" id="1858805.M5GAC7"/>
    <dbReference type="GeneID" id="63684769"/>
    <dbReference type="HOGENOM" id="CLU_025689_0_0_1"/>
    <dbReference type="OMA" id="GMTKWCR"/>
    <dbReference type="OrthoDB" id="2504561at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037679">
        <property type="entry name" value="Apc5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830:SF9">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="8">
        <location>
            <begin position="192"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="683" mass="78348" checksum="43CC5BF68ACC151A" modified="2013-05-29" version="1">MADAPATRTHVLRPHHVLMAAVLRLTHTPEWTFTDLFLLEVYKLVMQEISEIYQPLPYRDFYRKIQELDKGGKKVYPRDIEIMASCLDGFIKQMTHPDFLHTLFTRKEEYGTQQSSAVFERRSYFGMFIRRTRLSMQKLSFSGMVKFIDDFQGWANATNMDGYAIESNWDIPGLLSYPTSDDDASRATADSFAEYEHAEHVGDITTAIESLRRFFAQRFSEENDSGFNQYTLLRLSSTYYLNGQMKAAKETIEEAMKVCRNAGDRYTLISCTALQRRINSFYPDHEPTPLRKGFKQLDVLWDLRRSLESGEPVSKCWKLLWFASAGAKDLSDGGKARDRASLASASSFMWKLSGIESLGRLWEDISLLHMDENAEDVRLTNIIWRTTSLVRQGQYDEAWTLIIDPSTWRPLTLQQAQQWQWELWCNMLTFAIRSERKGLVDYLRKTMPRYPSQQNYRGKMYDVEKGDLGAGECLRVGNNYINSRQYLIAMSPILTAATLTEYACNWHTHRTALIMIADLGIGLGMAPSGQRLIEEHLPQILRGDDLEQRAYACFTLARCMIANAEGDVSKLEEAIPWLQRALKDYEAIELIKSSQQVLYVLAVVYENTNDEEKRNAASQRLLDLESLVKQRHTRTVESKYMEMLELSVEILAYVATGGRRVGGDEASSNDNSIASTIPEYDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAM4</accession>
    <name>M5GAM4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632808.1">
        <property type="nucleotide sequence ID" value="XM_040771855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAM4"/>
    <dbReference type="GeneID" id="63686917"/>
    <dbReference type="HOGENOM" id="CLU_2996462_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="57" mass="6309" checksum="ADCBEE4572404CE3" modified="2013-05-29" version="1">MEEGGEEEEEQSQRCVGGNETGLSEAGEGREKNEEGRARVLSVWVDRLSLTVLSTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBI2</accession>
    <name>M5GBI2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632649.1">
        <property type="nucleotide sequence ID" value="XM_040777523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBI2"/>
    <dbReference type="STRING" id="1858805.M5GBI2"/>
    <dbReference type="GeneID" id="63692585"/>
    <dbReference type="HOGENOM" id="CLU_007321_1_1_1"/>
    <dbReference type="OMA" id="PRRALDM"/>
    <dbReference type="OrthoDB" id="26149at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="772" mass="83720" checksum="541CC164954E88CF" modified="2013-05-29" version="1">MSSNAPALKLSADMQSDPTALAAYLEEMNKLVAGALDTDPRWTKIAKAAKSLADILRHKTEDDLHGKLGKGGLPKSITGLVKGTPGVTGVPSRGLRVPALVEVLRVGANLCADDDDNRAIFLATDYVESVLGLLESYLPWIRLPSEKDPQSKQAQPLLLDDLRVIKTAVGALLNISASFDPAKEKLLRLGAPLIVLRIIVGLYPAGGWASTSASTSIPDMKEEWLWRFGVSNWAWRALDDWREPAEDSDEDSKPIFDGASLMYLLDPLPFVLPPFPEKLPDVFNQVATRLPLIDADLEVLEQVCMSLESLALDLAEVRQLLGRSAASHTPENSYLAQIIRFVEQVQAPSYWSEHSDKDRKRWERTLAFCKAAVIKAIIAVSGEDANLDVLWNEKDESGGWFVKTMLKWIRSYKPRTKVNANEDDGYHDMAICGTLALGNLARKESHCLTLASPPISLTANLIMLLDRKTDIKLKHGVIGLLKNMGHAPGNRAIIGDAGLLEALAASRIWEQKWDIAETVQLSAIGVSKHLAQSNALNSLRLLQAGTDHNSCLEQILGLVKRSDTIAVKSEGTRVLVSVIKSLCTNNGSAIPEHERKSAMDRLVNTRSTTALAELISRSQKYPLLLNEGIIAMTLLATQTHGVPHVLSAFFSSSPSTSTTTPTSTTFSLPGSAPTSPTAPVLVPDSPAVATLVAILVNKENKYQPELRANVCALLAAMGRRVPGAAEEDAKRQEVLHNQTREALNAVANGNGSESDKLDISQAAAAALLAWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBU7</accession>
    <name>M5GBU7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633363.1">
        <property type="nucleotide sequence ID" value="XM_040769581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBU7"/>
    <dbReference type="STRING" id="1858805.M5GBU7"/>
    <dbReference type="GeneID" id="63684643"/>
    <dbReference type="HOGENOM" id="CLU_057731_0_0_1"/>
    <dbReference type="OrthoDB" id="422106at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="51277" checksum="26E7C144C78D49E3" modified="2013-05-29" version="1">MYDDEEANVMLPYDDPTSPVPVTDEMVKEADALEGIGSLRDRLAPPTKVYRVENSKTIRGNLGKLKGISGGEEPEPEEDEMDLELGHRPNALLLQGEPIAHLPTDQVFAYVATYAPTPTGLEWVDDTTCVVLFSSGTVARGAHRFLLVDPPAEGEAFSDPLELQKAQPVPKAAWPEKARAEGAEEIRAALRGVVFVRQAKIADIKQRGARGQSRFYSTYGTQAGKEGYGRKRRREEEDEGEMSAEKRRALDEELDAYLRDESSEKQKRKKAEMDDQLDAYLAGDDAGLVNGHRGENGEYRQGRRMPRPRRERESTREDQAARRQHALDAQLDAYNEVDDVDTIPSKMRSDWTEEARAREFSPERRGGLGGRRSREEKRYEDAPVAMPMREEERRGKNEELEEEEGGGRRRRGRRGGRGPREMRNGDVPQRSNGRPRKELSELDAELEAYLNNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN8</accession>
    <name>M5GCN8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_105050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630871.1">
        <property type="nucleotide sequence ID" value="XM_040768024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCN8"/>
    <dbReference type="STRING" id="1858805.M5GCN8"/>
    <dbReference type="GeneID" id="63683086"/>
    <dbReference type="HOGENOM" id="CLU_001724_12_1_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080043">
        <property type="term" value="F:quercetin 3-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080044">
        <property type="term" value="F:quercetin 7-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF1494">
        <property type="entry name" value="FLAVONOL 3-O-GLUCOSYLTRANSFERASE UGT76E12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="517" mass="56814" checksum="925F96EDA4EA2001" modified="2013-05-29" version="1">MSRQCVSEDERTSLLLRIRVIAYGYPQPLMTPELNQIAMSMDPRDVHHPTLESCADGVEMMNELMIECPFVDKLGQRWSPVGEVPKTLVADVLMENIILPVKAKHNICVFVWWVGNIASFTRMFAPLKHGGRVEGYAHECDAIFADEERRNGRSFDDIARDMWIRDHRVPGDLIRLAGLPPYFQWEDFPQNIWDPSIYSSLVGGGNLVEAADGFMLHTVEELEMEAHKDMIQWAHLRPVLCIGPQLPAVLLSEHARIYAEALARLDVHYHASLVVGADHGHSNNETTSSGNERHTVDPTIAFLDKALIGYGPHSALYISFGSVFFPSEAHTKVLIETLLNLENPMPFIVTVLSGNFPEMLKAAVEQSGRGLAVSWAPQQAILSHPGMGWMLTHCGGGGTFEALSAGVPVIAWPFMGDQPQNALSVSQVLDTGFDLLQIRTGAPGSPALRDDINAGGTTILGTEEAIKSELRDILERAQGKDGARKRENAQKAKAVILNAVNQGGSAHKAFGELDLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDJ8</accession>
    <name>M5GDJ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_22103</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:12706"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="4"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629362.1">
        <property type="nucleotide sequence ID" value="XM_040772675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDJ8"/>
    <dbReference type="STRING" id="1858805.M5GDJ8"/>
    <dbReference type="GeneID" id="63687737"/>
    <dbReference type="HOGENOM" id="CLU_055432_0_0_1"/>
    <dbReference type="OMA" id="HMHASAC"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000235">
        <property type="entry name" value="Protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="228" mass="24823" checksum="05E8C97AB1B91947" modified="2013-05-29" version="1">MAWMCSGRTNKELVQRMIDSKLIKSERVAAAMKATDRASYVRYKEDAYVDSPQSIGYAATISAPHMHAHAAENLLPLLFPGAKVLDVGSGSGYTAAIFHRLVSSEGKKGLVVGVEHISELTDWSVENLKRDGLAKAVEDGEIVMFAGDGRKGDPERGPFNAIHVGAASPELPQVLVDQLAKPGRMFIPVGTNEQAIIQVDKDEQGAVTMKELFGVMYVPLTDKTKQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK0</accession>
    <name>M5GDK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629367.1">
        <property type="nucleotide sequence ID" value="XM_040772677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK0"/>
    <dbReference type="GeneID" id="63687739"/>
    <dbReference type="HOGENOM" id="CLU_676178_0_0_1"/>
    <dbReference type="OrthoDB" id="10255522at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="213"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="45678" checksum="BF6B0AC649471684" modified="2013-05-29" version="1">MPARKSRNPPKKESVVKEEAVKEEAAKEEVVEKEAVKTKPGPNEVALPVIYTDNLTHDIFLDRGYTVTQARSYAIFSAREHVLKETKVDILNKEHPWLPPPKVESRAEVFKKVNENIVATLVYRKTTLDDTEIGNLPSDEQPAILVHGKEHPVTLTLKSERAKALGAELDAEKKASSSEKATEPTKKQANDAPADKSDMATLQAQFRMVLDVCQKSEERIRGLENTIDELKADNAQLKADNAQLKADNAQLKADNMQLKADNKRMDSAIAQLQTRLQDVEGPLSRLSLRITHDMARKKLAFLLDPTLNESTWSGFSWSDFVTKFPMEKARAALSNDSPWLKDAQILPLLYLPDKYKSFRSAGSRVAHEAEEPELALAILRLPDKPQRRAFLSLHEIVHGKPADFPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK4</accession>
    <name>M5GDK4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">agmatinase</fullName>
            <ecNumber evidence="4">3.5.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_66613</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>agmatine + H2O = urea + putrescine</text>
            <dbReference type="Rhea" id="RHEA:13929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="3.5.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="4"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629377.1">
        <property type="nucleotide sequence ID" value="XM_040775823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK4"/>
    <dbReference type="STRING" id="1858805.M5GDK4"/>
    <dbReference type="GeneID" id="63690885"/>
    <dbReference type="HOGENOM" id="CLU_039478_1_1_1"/>
    <dbReference type="OMA" id="CIDAGFV"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000006">
        <property type="entry name" value="Agmatinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF30">
        <property type="entry name" value="AGMATINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00050304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="376" mass="40244" checksum="3C831CA587670024" modified="2013-05-29" version="1">MPLGYVKFPYQATYPGDNEVTADSIFSGITTFARLPWSQCLTDKTADFDIAFLGAPFDTGTSYRPGARFGPSGIRAGSRRLTLYGGYNVPLETNPFKMLKVVDCGDIPVTPYDNARAIQQIEDGHKELLHRTPYSPLGNDSLTGQPLIPLSLDGKHHPRVITLGGDHTIVLPLLRSIYSAYGAISVIHFDSHLDTWKPSVFGGSDSKGIGGGALNHGTYFYWASQEGLINNGSSIASHGAIRTTLSGPADYENDDTAGFKRIEAREIDTLGVDGIVAKIRETVGDKPVYLSIDIDSIDPAFAPATGTPETGGWSTRELRAIIRGLDGLHIVSADIVEVAPAYDTNAELTTMAAADVLFEVLGIMAKTPLGKVASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDR8</accession>
    <name>M5GDR8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_47116</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631656.1">
        <property type="nucleotide sequence ID" value="XM_040774741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDR8"/>
    <dbReference type="STRING" id="1858805.M5GDR8"/>
    <dbReference type="GeneID" id="63689803"/>
    <dbReference type="HOGENOM" id="CLU_012442_0_0_1"/>
    <dbReference type="OMA" id="TIAKLWP"/>
    <dbReference type="OrthoDB" id="377083at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="651" mass="71644" checksum="2B78B6D977EB97D1" modified="2013-05-29" version="1">MNSLLPKLNDIHTLRERRTPPNGRRASFHVSAQQQLKPELEKDGDIGRLWMTEERDYRDCIDSGIITALLLGPLVSASALLVSLPAAEFGSPLSSLSPRWLVEPPLASSTIPPTVALVRSRRNMFEMASLCSFLISIHFESSRRADIRVAKEREGGVRSGLLPKSELRRFGSYVGMTVIMVSIAVGVKTAATSTGSSLWSELSMFDVLTVSLFYQFCLYVMIRLARRGFTLGELCFVAQCATALVMETTNLTISRIWPISTPFIKTFRRPTPLLIYQLALIPGCLLAGFLLSPLLVLSRNIAQKPLHRLRFPEDKLIQRRGLAAAVYAGFALFIGGVVGVWTQWCLGWRNPWAWVVFWLLEGRRPWSRLVLLGYWGILGSLSVAGWNRQLARQRRYRHLNGHGAGHNAPARTGNGTLTQDGHVSESAIQSPVGTASSSVTEMLDAADKHVPTLGLNARRKFFHALAVLMFLPGIIIDPAFTHLSFSAAFALFTFAEYVRYFALYPFGAAVHVFLSEFLDHRDSGTAILSHFYLLTGCAGSIWLEDSKPILELTGVLVLGVGDALASIIGRKIGKHRWSSASGKSVEGSAALAGSVWLCALLLRLSGIVDPFSLWKYGCAIGLGSLLEALSMQNDNLVLPLYVWCLLALFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDS5</accession>
    <name>M5GDS5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629547.1">
        <property type="nucleotide sequence ID" value="XM_040772498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDS5"/>
    <dbReference type="GeneID" id="63687560"/>
    <dbReference type="HOGENOM" id="CLU_2621976_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="8841" checksum="E807856B283959E2" modified="2013-05-29" version="1">MHTDHRRLSGCARVFKSRVLPSSKLTPPSISLSHLPSVRIHLAQSRRILLHQALYTDQQPSSERVSEISNAPIHPLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE58</accession>
    <name>M5GE58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629892.1">
        <property type="nucleotide sequence ID" value="XM_040772358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE58"/>
    <dbReference type="GeneID" id="63687420"/>
    <dbReference type="HOGENOM" id="CLU_1643647_0_0_1"/>
    <dbReference type="OrthoDB" id="10392873at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067769" evidence="1">
        <location>
            <begin position="18"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="161" mass="17297" checksum="A4F93ABBF6BFA710" modified="2013-05-29" version="1">MLALTAILAALIIVVSAAPHGPTRTVEKREPHPAVITLPTPGTEIWAPWDSDISSTPGYFQFPLIMVDGETMSTYARVALTNSSGTYPIGEEIHVYDSWTFEAIVASSLSVVAPGAYVLDVQEQDSSDDGWYTAVSTNVTVYSEMCGTDPTCCWSCCPICP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE68</accession>
    <name>M5GE68_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629917.1">
        <property type="nucleotide sequence ID" value="XM_040769975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE68"/>
    <dbReference type="STRING" id="1858805.M5GE68"/>
    <dbReference type="GeneID" id="63685037"/>
    <dbReference type="HOGENOM" id="CLU_010119_6_3_1"/>
    <dbReference type="OMA" id="AKYEVVT"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="189"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="37061" checksum="3DAEBC50B9219F64" modified="2013-05-29" version="1">MVASTLLSTGNGTRVLPPPTELIIEGASAFEAIPIIDLAQENRTLLVEKIREACLKVGFLYIKNHGIPQSTINATLNEAHRFFDLPLTSKQALDIHLSPAFKGYTALLGENSDPANRGDLHEGFDVGSESEQGEMRGNVWPPETELPGFKEKVMEYYDAVLSLGRRLFPLFALSLSLPEDFFDDKILHPAAIMRLLHYPSQTGPTDDRILGIGAHTDYECFTLLYQDIVPALQVLNAAGKWVSAPPIEGTFVCNLGDQFARWTNDVYVSTVHRAINRTGQERYSIPFFFGTDYDVKLEALPSCVSEDRPARYEVVTAGEYVKSRLEETYAQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ3</accession>
    <name>M5GEQ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630372.1">
        <property type="nucleotide sequence ID" value="XM_040772212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ3"/>
    <dbReference type="STRING" id="1858805.M5GEQ3"/>
    <dbReference type="GeneID" id="63687274"/>
    <dbReference type="HOGENOM" id="CLU_015513_0_1_1"/>
    <dbReference type="OMA" id="WPPQLKE"/>
    <dbReference type="OrthoDB" id="199574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="281"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="478" mass="54648" checksum="FC7F0B39BD8D194D" modified="2013-05-29" version="1">MSMTAWPPQLKLWLQKCLSEATPSVKLAVMDEIKQIVAKHYEDGTLETTDWDKVEVKSMKPFVMPKIPSKRKLDTLSAGNVLEKPAKAAKKATFTNSWETTNTSSNGFATDSLRQRREDRFAREHEIERQRQAGERPAQGYSRHVNTPPANGASLLDRMESLRSTPKKKSKFVYQNNVENAYDPNVLNWDRHTIVGRSKDLEKSYLRLTSDADPANVRPLEVLVQALEVVLKKYKAQTVKYDYVCDQLKSIRQDLIVQRIQKSFTVKVYEIHARIAMEHKDLVEYIQCSSALHSLHALGLDGHYEEFLAYRILYFVYTKSRSDLNALIAQLTPAQKATPCIRHALDVQKATATNNYHAFFDLYLNAPNMGPYMMDFYAGRERCHALIIMCTAYKSLPISFLTKELGYTASHQTVAFLEENQAGYFVGMDRPTANQPTGQWKRVQKVIPDHDKILDCAQAKPNLVKAVAKYHKLDIKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GES8</accession>
    <name>M5GES8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_21105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630447.1">
        <property type="nucleotide sequence ID" value="XM_040772235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GES8"/>
    <dbReference type="STRING" id="1858805.M5GES8"/>
    <dbReference type="GeneID" id="63687297"/>
    <dbReference type="HOGENOM" id="CLU_015166_3_1_1"/>
    <dbReference type="OMA" id="WRPMRGM"/>
    <dbReference type="OrthoDB" id="43906at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048250">
        <property type="term" value="P:iron import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000029">
        <property type="entry name" value="Solute carrier family 25 member 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="15"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="111"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="202"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="33108" checksum="114B746B650C162F" modified="2013-05-29" version="1">MAVEDEEYEALPMGVGTGVHMLAGAMAGISEHAVMFPVDSIKTRMQVFSTSPAAVYSSLGNAVARISSTEGLRTLWRGVASVIVGAGPAHALYFGTYELVKETTGGNRPGHHVAATALAGACATISHDALMNPFDVIKQRMQLYGSSYRNVAQCARSVYQNEGLIAFYVSYPTTLMMTVPFTAVQFSTYESMKKFLNPEGTYSPLTHVTAGGIAGGVAAAVTTPLDVAKTLLQTRGTSDDIRIRNARGMVDAFKIIWQRNGIWGFARGISPRVLTYMPSNALCWLCYEFFKVVIGDASRGSSHATVAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GET4</accession>
    <name>M5GET4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_21115</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630462.1">
        <property type="nucleotide sequence ID" value="XM_040772241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GET4"/>
    <dbReference type="STRING" id="1858805.M5GET4"/>
    <dbReference type="GeneID" id="63687303"/>
    <dbReference type="HOGENOM" id="CLU_003041_16_3_1"/>
    <dbReference type="OMA" id="CYRSWVR"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000160">
        <property type="entry name" value="ATP-dependent RNA helicase DDX3X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="199"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="400"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="44"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="569"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU03568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="644" mass="68694" checksum="0498F8F6EF56F1B6" modified="2013-05-29" version="1">MNNGNANVTNSIEEQLASLNLGGKTAYIPPHMRSLPSVSPSIRPANNGTGAVSPSIDPRQPSYSRGGYGGGFGGGRGGYRSDGYDGGHSRGGPGGYDRGGAGYPSRVSDGSGVWKDDQHVLGGKNARMEQELFGDPNDPTKQHTGINFEKYDDIPVEATGVGIPEPITAFNSPPLDPVLLENIHLARYLTPTPVQKYSVPIVAAGRDLMACAQTGSGKTAGFLFPILSASFTNGPTAPPPDTAGYGGRRKAYPTALILAPTRELVSQIHEEARKFAYRSWVRPAVVYGGADIGQQLRQIERGCDLLSATPGRLVDLIERGRISLANVRYLVLDEADRMLDMGFEPQIRRIVQGEDMPDVNHRQTLMFSATFPRDIQMLAKEFLKDYIFLSVGRVGSTSENITQRIEFVEDHDKRSYLLDILTAEGQNGLTLIFVETKRMADMLSDFLMGSSIPATSIHGDRTQREREQALATFRSGRTPIMVATAVAARGLDIPNVMHVINYDLPSDIDDYVHRIGRTGRAGNTGIATAFFNRGNRNIVRDLLELLREANQEVPQWLLDIASENSFGGGGFSRGRGGGRGRGGRGGANRDYRTQGSGGGRGGYGGGGSGGNYGGGGGYGNNYGGGSGYSGGGYSGGSGGGGSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEV8</accession>
    <name>M5GEV8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_113777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632621.1">
        <property type="nucleotide sequence ID" value="XM_040769697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEV8"/>
    <dbReference type="STRING" id="1858805.M5GEV8"/>
    <dbReference type="GeneID" id="63684759"/>
    <dbReference type="HOGENOM" id="CLU_006493_9_3_1"/>
    <dbReference type="OMA" id="GCVGYLD"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="9">
        <location>
            <begin position="37"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="225"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="501" mass="56089" checksum="DD1BEFD48D3F5958" modified="2013-05-29" version="1">MDINSLVPNPTLKRVQDALIDRHLGNCIPVYLELPADLFTPCMAYLRVAKDAKYSFLLESVIAGENVARYSFIGADPLRVIKTGPGLDFEGDPVIPLQKELSMYKYVKIPEVPTFTGGAIGYVGYDCVNYFEPKTARNLRDPLGIPEAFFMLCDTIIIFDHLYQSIKVVSHVFAHATSRSDLPILYETAVAKCRRVARMILSPYTPAVRQAPIVLDQKTTSNVGKEGYERFVSELKKHIIAGDIIQAVPSQRLSRPTTLHPFNAYRHLRQVNPSPYMFYLDCGDIQLVGASPETLCKVTRNKVENHALAGTVRRGKSPKEDEELGAQLQASEKDRAEHIMLVDLARNDVNRVCKPETVKVEELMKLKMYSHVIHLGSTVTGELRAGKTRFDAFRSIFPAGTVSGAPKIKAIELVQDLERERRGVYAGAVGRFDFASDEMDTCIAIRTMTFKDGVVYFQAGGGIVYDSVEEDEYIETLNKLRANVKAIEEAEKYHYALQNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEZ0</accession>
    <name>M5GEZ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TBP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_75233</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632726.1">
        <property type="nucleotide sequence ID" value="XM_040776120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEZ0"/>
    <dbReference type="STRING" id="1858805.M5GEZ0"/>
    <dbReference type="GeneID" id="63691182"/>
    <dbReference type="HOGENOM" id="CLU_060161_1_3_1"/>
    <dbReference type="OMA" id="FHFKIAE"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="26044" checksum="831D82F56B8A1501" modified="2013-05-29" version="1">MSYHGLSLPSSGPLVPQQRPPLQPPPVQQLTPPATEGAKTPAAPPTLEQQHITAVDGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSRLASRKYARIVQKLGFDTRFVDFKIQNIVGSCDVKFPIRLEGLAYSHGQFSSYEPELFPGLIYRMLKPKVVLLIFVSGKIVLTGAKVREEIYTAFNTIYTVLQEFKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFF6</accession>
    <name>M5GFF6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_92327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633131.1">
        <property type="nucleotide sequence ID" value="XM_040777060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFF6"/>
    <dbReference type="STRING" id="1858805.M5GFF6"/>
    <dbReference type="GeneID" id="63692122"/>
    <dbReference type="HOGENOM" id="CLU_066245_2_1_1"/>
    <dbReference type="OMA" id="DKWGIPT"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="256" mass="28630" checksum="824FDF56E6DFDD53" modified="2013-05-29" version="1">MSAEDCSDGPMWTQTMALKKLVRSQVKEVLEKLSTTLVENESKLITQHVLRSSAYKNSRGIACYLTMEKQAEVNTHAIVVDALKSGKRVYVPRINFDRLARKNSRAANRLPGAGKYQWMSMLRLYSLHDLNGLSKNTWGIPEPTVDGPEGIKREDLASMYTENVDLVLMPGVAFDRNLSRLGHGKGFYDKWLSHYASTHSKGSRPILMGLALAEQIVPRIPIEPHDWPLDMIVTPNGIMTPEGQPLDQVQDGASEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFW6</accession>
    <name>M5GFW6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_44645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vacuolar assembly and vacuolar traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the VPS41 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633531.1">
        <property type="nucleotide sequence ID" value="XM_040774597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFW6"/>
    <dbReference type="STRING" id="1858805.M5GFW6"/>
    <dbReference type="GeneID" id="63689659"/>
    <dbReference type="HOGENOM" id="CLU_001285_2_2_1"/>
    <dbReference type="OMA" id="PQLVWQD"/>
    <dbReference type="OrthoDB" id="244107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000350">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 41 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016902">
        <property type="entry name" value="Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028921">
        <property type="entry name" value="VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="7">
        <location>
            <begin position="37"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="5">
        <location>
            <begin position="603"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="894" mass="101410" checksum="295364CFCDF76374" modified="2013-05-29" version="1">MYQNGRQEVEEDDPEDVEEEGEDGDEDGEEEEEEPTLKYETMKTPAFDFLQKETISAIYVSTEFMTLGTHNGVVHVIDHKGNNIKAYRSHSATISGIDVDYENQFIASASVDGKVIIHSLHTPENYSFDFRRPMRTVALEPGFAHKNGRQFVCGGMAGTLLLHDKGWMGHKAQILHSGEGPIWETSWMGNLIAWANDLGVKIYDTASHSRIGFIDRAVDAPRADLFKCNLRWRDEQTLLIGWADHLKVARVRQRPNPPPGMPPLMIEITSHFALDYMVAGIASYQNSYLILSYISPDTYMEEETEDRERQRRKAALPPEMNLISRSGEQEASDVLAIQGYGTYGCNDYALGPSIKEKDPFFVVMSPKSIIVARPRDRSDHVDWLVEKRRYAEALDEVEKMGETREWNVVSVGEKFIESLVEEGQFDKAAELCPKVCRDNGKAWEDWIFTFVQKGQLPAIVPVIPTQEPQLSHVVYEMVLAHYLANNRDELLRTIRTWPHGIYDSSAIVVAVQGELEHTPSSAILMECLAELFIQNRQPGRALPYLLRLRKPNVIDLIREYNLFSAVKDQVLLLVEFDQDLEQKYRVQGEGSMASVLPRRSAAISLLVEHTDSIPIPRVIQQLEQRASFLYLYLDALFDRDPLLTSDYADRQVQLYAEFSYKRLMDFLRASNYYSLERAYRICKERDFVPEQVFLLGRMGNNKAALNLIIERLGDVTRAIDFAKEQNDEELWEDLLKYSETRPAFIRGLLENVGAEINPVRLIRRIRNGLEVPGLKSALIKILQDFNLQISLLQGTQTILYSDCTDLARRLQSSQVSGAFCSATMTCPICDLPLFVAPTPSAETQQLALAFLCGHIVHATHVKGASELPAQQPEIIRGFLGSQARTQDRLGQKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGH5</accession>
    <name>M5GGH5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632392.1">
        <property type="nucleotide sequence ID" value="XM_040771736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGH5"/>
    <dbReference type="GeneID" id="63686798"/>
    <dbReference type="HOGENOM" id="CLU_895887_0_0_1"/>
    <dbReference type="OrthoDB" id="3362964at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="106"/>
        </location>
    </feature>
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        <location>
            <begin position="142"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="33572" checksum="BB082A2A54E36C20" modified="2013-05-29" version="1" fragment="single">PPSRPTSPSHKSTPAPPIMDPTTIARISRRKLALAAMEASTRDSLELRRVVLIQGAMHAAANASAATHRPPSPPRAPLSPAPPQIVVSPPPPPPSPPEPQFQFPSFGLEELQAEERWFDAVLDELDQDMDEEDEVDHLITVHTVQESTDSSSDGTVSEAGSEGMDLEDLFYPPPPPYSLIPASAPPPEEHQESEPKAITFDASHPPPLPDSFAADAWDDYDDGSEKVSIATLFSDVDLSSGVSTTATLTISAAAVAAASSTQHQKPQKLERDYGSRKGMRSTMPPGYGMYPPISPYELVWPGRYDYDAVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGJ1</accession>
    <name>M5GGJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor CEF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pre-mRNA-splicing factor cef1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20015</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632472.1">
        <property type="nucleotide sequence ID" value="XM_040771763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGJ1"/>
    <dbReference type="STRING" id="1858805.M5GGJ1"/>
    <dbReference type="GeneID" id="63686825"/>
    <dbReference type="HOGENOM" id="CLU_009082_0_0_1"/>
    <dbReference type="OMA" id="KMGMAGE"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="13">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="13">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="115"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="234"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="395"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="512"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="781"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="523"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00069095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="849" mass="94822" checksum="1AC96593D91AFE91" modified="2013-05-29" version="1">MVRTIIKGGVWQNTEDEVLKAAIAKYGKNQWARISSLLVRKTPKQCKSRWYEWLDPSIKKTEWSKTEDEKLLHLAKLMPTQWRTIAPIVGRTATQCLERYQKLLDEAEARENEELGLAGPGAEAGPAEDIRKLRPGEIDPDPETKPARPDPIDMDEDEKEMLSEARARLANTQGKKAKRKARERQLEEARRLAMLQKKRELKAAGIIMRLKSKKKGMDYNADIPFEKQPAAGFYDTSEEQSKTYAAPVGQSLRRLEGKRKPEEEEAERKKRQRRDAEKKGTPQHQTQFVAARDAQIQKLKEAEQISKRRQLVLPSAQVGEAELEQIVKIGQAGENARALVAGEGDEASGQLLGEYEGLSQARMARTPRTAPQEDNIMAEARNLRNMTQTQTPLLGEENTPMHGPNAPGTGYEGATPRRSVNFTPNPLATPRENGALDVSATPRTDAGSAYGQTPLRTPMRDSLNINITDDGSVYGMTPRAGRGQLTSAKRSLKPGFMSLPAPKNDFEVMMPEDEEEEEAEDGVSVREEDSAERDARLKRRREEEERKALARRSTVVQKGLPRPPNVNAAQILKQLMAQYSDENEAAAVERLIDTEMVLLMKHDSVAHPVVGTSIAGGTRSTYVQPDDEAIAWARAAVHHEFAESLGFPGANEDQIKNMVVMLSAEEEKETRDIGWSKIKEEMCFDAKTQTWVEKNALSPADRIEGMSALLDSYRDQLNKEGVKAGKAEKKLTVTLGGYQARFTALSKRVGDGFADLQKTHGDLVNFSQLAAQEGVNGPRRLESLREEVDVLERREKSLQGRYQELDEARRERVERIAALEDQLFADAEAANEAAMEEMDRAAGVDVEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGV9</accession>
    <name>M5GGV9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633062.1">
        <property type="nucleotide sequence ID" value="XM_040767717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGV9"/>
    <dbReference type="GeneID" id="63682779"/>
    <dbReference type="HOGENOM" id="CLU_444819_0_0_1"/>
    <dbReference type="OrthoDB" id="3020126at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="614" mass="68363" checksum="4C3681B82683B49D" modified="2013-05-29" version="1">MGFAVSGQKRCHSPAGPKNSSPIKGKGKGKGKGKGKWKDKGKALFTSTFFVEREDDSDEEDELNGRFKSEEREESLLLPPKRQRVEWLHTCTVEGIGSSQGTSINNGEIFGPGEEEVMEQDLSYEIEERMELHQVYMQVLETVEELEEEQQELEEELWVEEGEEQAEEQEGQMFQMDTIASLPLVQAPFSNEAATMKMLELSRVSGEAESFNPTFGADGQSMLKEHWEKMESWEGGDMGSPILGDSNSSHDGLAELREEPLNPVDFYFSEPHNPCSSHLTLPLSKVSIQMRVNVEKWQNTWLLLAFSNWLACGHLATTSGAFGCKVIKAAMSREVHITSFPTFSIMAFIKSPGVYLTEFLALQDFLASPDEGVTVCMVKSAVVGDEVPKAKVLQSWIHYGAQGFNPHLKVLSHGVFDIPASPQGMGKINFGVPNAVHQVCVDIHLLTRDIYVSTSFMGKGSLTLPHIDLIFCHVTEIAVRHKLNGAPNKLWFLAPLTLKNLALLSRTVQGTAGHDFGAQLIAELEDLYWVCQTDDIGFILPAGWIHCVESFAILLHTGFKFQLANIGTEKTGQEMIKVLEEDLAHWAHVRSAQAWVREAQKELDTAKGKKFSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMY7</accession>
    <name>M5FMY7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_25673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JH795896">
        <property type="protein sequence ID" value="EJT96515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623413.1">
        <property type="nucleotide sequence ID" value="XM_040774261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMY7"/>
    <dbReference type="STRING" id="1858805.M5FMY7"/>
    <dbReference type="GeneID" id="63689323"/>
    <dbReference type="HOGENOM" id="CLU_367853_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="353"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="758" mass="83662" checksum="EE4E6CC2332BB81D" modified="2013-05-29" version="1" fragment="single">MHWLALMDAEFASLTEGADALKLYDIAIKIASDNDWILEEGWALYLAGSHFIRCARCKSFGSEMQRRGIGRQNQWGALGIVISMEKSCEKSDSIFMRAVTVDVGTQTEQIDPIPRSAYLASRTNFSQSGVLADSELLSLSADQFAEIIKWTQVISSEINLSVSLEKLTNDMAATSGSDKVVVVIRADHGDMAVSSSVYPPEPVQMHDEPIPLSELEDPLAVQIMQQVIHSKEPVYQRDATEDPRYSVAAKSSLDKTILCFPIYHAGRGDMMGCIYMASSKPYAYAPSIVTMMTVLAQQASISITNCLLFQDVTKATRNNIRMINSQKEALEEARRSREDALKAAKTKSNFLASMSHELRTPFSSFYGLLDLLSTTDLDWEQRELVQTARQSCELLLEIIDGLLDYSKLEASAVKLESIPLNVEDLVGNAVELLTHLAVKRGLDLSFFVCPDVPFYILGDLSRLQQVLMNLLGNALKFTEKGSVKAVCSVDQSGEIPCGENQVVLKWSVADTGIGMSPHDMKNLWQPFSQVDQSTTRKFGGTGLGLSICLSLVKLMHGDVGVSSELDKGSQFWFRIPVTIHESAETAKEKALMQAYRLNLINSDAMVLLSSPTDTTRDLLQAALIGVKSLVCNSTEDTDIFLRDAGMKKDRVEFVVVDEHAEARIDDIAHLLQEYPSLSHAKIIHLCAPSADFLNRRPGAKAGVAIEAVAPEMHTYIHGGLIARMAKPARTQKFLRILSRMWDARSGYTNGSTLRDGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN57</accession>
    <name>M5FN57_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623763.1">
        <property type="nucleotide sequence ID" value="XM_040769370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN57"/>
    <dbReference type="GeneID" id="63684432"/>
    <dbReference type="HOGENOM" id="CLU_1570605_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="17652" checksum="9BDCCA1FFAC19045" modified="2013-05-29" version="1">MPSAPAEAAHDGEAQGGCFNWAHVLKLMAVDKAEGDIAATATGIANISSAAADKASASVGGLPNASTEKGVPVTNTMHIQEGTAHDLGDGEEDEDEYEASDYGVEDAIFMDEEASIGTGVPMTEISPVTAAPAAGPRMAPLKKTRKQNHAKKDHKYLCLQQGYVRATQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN86</accession>
    <name>M5FN86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkaline phytoceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_85433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623908.1">
        <property type="nucleotide sequence ID" value="XM_040776733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN86"/>
    <dbReference type="STRING" id="1858805.M5FN86"/>
    <dbReference type="GeneID" id="63691795"/>
    <dbReference type="HOGENOM" id="CLU_063293_3_0_1"/>
    <dbReference type="OMA" id="IMFEPLR"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="287" mass="32438" checksum="0E9EFEC4A4FD128D" modified="2013-05-29" version="1">MWPVRQPVTPVHREGQKTFGYWGPHTSSIDWCEDNYVNLPYIAETWNTFSNIPYMLLGLHGVLLTQGLPHRARFALLHAGVALIGVGSFIFHATLNWYAQVFLDELPMIYVSTLCLYVILMAGKDAWWKRLVAPALVMLALAVTVIYFWYPNPVFHQLSYAFIQFLTTARNYVLLQTVPPSVRKQCHRILWSGAITFLLGFAIWNVDNQFCDTLTQYRGHYGDVVGALTQGHAWWHVLTGIGGSRIVVGVTYLALCVEDPDGYEIGTSLGCMPYVRAKAKVSHKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNF8</accession>
    <name>M5FNF8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNF8"/>
    <dbReference type="STRING" id="1858805.M5FNF8"/>
    <dbReference type="GeneID" id="63689090"/>
    <dbReference type="HOGENOM" id="CLU_1562835_0_0_1"/>
    <dbReference type="OrthoDB" id="10491487at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="171" mass="19070" checksum="5461A564CA9A15B1" modified="2013-05-29" version="1">MGNIDLALFLARLVSALVLFVLSLWLTLIKPDIVPSRTPRRKAIVICGSALAALWIADACIIAGRGLLEKLREPDEAAWKEEQIAIILNFLAWSGVVGIGVWKETYTNEIWTSALLKFLTIFAFSAEVVTLALLSLVLHIFEYPVHKPKYTWIDPRCSGSHPLRTDANPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNN4</accession>
    <name>M5FNN4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNN4"/>
    <dbReference type="GeneID" id="63689054"/>
    <dbReference type="HOGENOM" id="CLU_1277582_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="216" mass="24301" checksum="D5767FAAF59FCCB6" modified="2013-05-29" version="1">MPQRARDRSALASPHPADQARATRALQVARQQLEHPRDRHRSKGLLGCTCGCASAAPSRCTCRIADPVHFHSGSILMIVDCDRYTHEPVGEFRRSRGGRPLELKSDDMRRWTVSELQYFGVYGDGKYDGPEREKRHPGSTGVDLLAIAKPGKGRRGVPKGYELVQRPREVIVLDDDDEAEGEWEDDFELVDMPARGKRKGRTFAQAVKGKGKRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNR5</accession>
    <name>M5FNR5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase CHL1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 10">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_25669</name>
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    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNR5"/>
    <dbReference type="STRING" id="1858805.M5FNR5"/>
    <dbReference type="GeneID" id="63689322"/>
    <dbReference type="HOGENOM" id="CLU_006515_2_2_1"/>
    <dbReference type="OMA" id="GWISKTI"/>
    <dbReference type="OrthoDB" id="267079at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT96518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="532" mass="59757" checksum="C0B1F5BBC8D2A65B" modified="2013-05-29" version="1" fragment="single">MKERLEEARRKEERLRKIEAVRANRKRKLEEMISEDMDEAEFLPDDNSGGGGEDAMLPQTKVLLDKLMGKQRQRIDVELEEPDCTKIYYTSRTHSQLSQLVSELRKTPLYEKTRFVALGSRRNLCINHELRNKAGGDLDEACRDLVNNKQGKGCPFLPSHDEMSKMLDFRDHVLAAPKDIEDLVTLGEELKICPYYGSRQAIKQSEVVTLPYNLLLQKSAREALDINLHDQVVVIDEAHNLIDTVLSIHSVTLSTTTLETCLGQLAIYVTKFRKRLASKHLIHLKRLVAFLSALENFCLDWQSADATKNEEMLSIAGVAESLGQKVDGINLLEIEQYLKESKIARKISGYNDKLAEDQVKNGDTKFTKSRRTTNPPLHAVQAFLLVLMNSDEDGRVHLSKSVIDGKVVVTLCYQLLNPSPSFQEVVDEARAVVLAGGTMEPISDFRTQLFPRLLENRFATFSCGHVVAKENLTALAVSRGPKGGDLSFKYSSRGDKGMASELGQALLNFLSLVPDGMVVFMPSYAFLNQLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNV8</accession>
    <name>M5FNV8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_58425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624878.1">
        <property type="nucleotide sequence ID" value="XM_040775497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNV8"/>
    <dbReference type="STRING" id="1858805.M5FNV8"/>
    <dbReference type="GeneID" id="63690559"/>
    <dbReference type="HOGENOM" id="CLU_000288_6_8_1"/>
    <dbReference type="OMA" id="AKWHEDY"/>
    <dbReference type="OrthoDB" id="3045137at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="25"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15230" checksum="37DE70D943D95F27" modified="2013-05-29" version="1" fragment="single">MPGTRTALLSEITAWIQAPSSESCKIYWLTGLAGIGKTALANSVAIIAAEKGWLVSSFFFNRMSDERNKPARFVTTLARDLAGRNTGIADAIAVRLNYDVGLRTTPDIDRQFQELVIEPCKNWNRLEPAVFVVDALDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPD7</accession>
    <name>M5FPD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623896.1">
        <property type="nucleotide sequence ID" value="XM_040774153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPD7"/>
    <dbReference type="GeneID" id="63689215"/>
    <dbReference type="HOGENOM" id="CLU_2885723_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="63" mass="7126" checksum="E936D447C3B667AB" modified="2013-05-29" version="1">MPNGRSKDRRLLRASGQGQVAGPCEVCCFRNMVSEYEHNMGYVMEFVTLVEGMEKLNDVGTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPI7</accession>
    <name>M5FPI7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625493.1">
        <property type="nucleotide sequence ID" value="XM_040769065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPI7"/>
    <dbReference type="STRING" id="1858805.M5FPI7"/>
    <dbReference type="GeneID" id="63684127"/>
    <dbReference type="HOGENOM" id="CLU_1695410_0_0_1"/>
    <dbReference type="OrthoDB" id="5946233at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="18249" checksum="95656E5FCD9490EB" modified="2013-05-29" version="1">MHNTSILQANKNKILPLGWPEHILYHLDRFGVRSYKVLILKVEFGEAEKLYMPTDHPVFQLMPQDFDIQIMIVYEEIGQLRVTTQSFWQIYLQLQDALAGSKDLRESLASQEEWEIRICHEHMDLENSVRESDEDGNGEEEEEEDVNVMQEVEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPJ5</accession>
    <name>M5FPJ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_25238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624011.1">
        <property type="nucleotide sequence ID" value="XM_040774077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPJ5"/>
    <dbReference type="GeneID" id="63689139"/>
    <dbReference type="HOGENOM" id="CLU_871604_0_0_1"/>
    <dbReference type="OMA" id="EEITHVW"/>
    <dbReference type="OrthoDB" id="3349377at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="34821" checksum="82D6981E8D4EAEFA" modified="2013-05-29" version="1">MSTLALTPGVTSEAFPYVCSELAAAALFTYDILICLDEEITHVWWSPRSIPKTLFMVSRYVGLAVIGTMPVIAFYADPSAACRAYLPVQFLVLQAVAFCCDGLLLMRVAAVFNHKRWLCRTLYGLYTLAYLIESAIAILNFVTSLKATPVPDEWDCIITRHASGGNLLDTIVTLPILIFNLILFTLTVIHLSPYWRAREKNQTHILTLILEEGTIYFAIVCAALLAETIVPLLLTDDLGVAWLALIPIASNRLFLSLRAAASGSLNSGDDTNPVSYTPASALVVRPSGGSEQTTGQSTSNVVQRLNTVSSRLSTTTPWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPR2</accession>
    <name>M5FPR2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D123-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_83255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625618.1">
        <property type="nucleotide sequence ID" value="XM_040776619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPR2"/>
    <dbReference type="STRING" id="1858805.M5FPR2"/>
    <dbReference type="GeneID" id="63691681"/>
    <dbReference type="HOGENOM" id="CLU_034402_2_0_1"/>
    <dbReference type="OMA" id="TFPDPNF"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="38691" checksum="9D62DAFFDF2147DF" modified="2013-05-29" version="1">MSPLLFPPITRSQVLACQVSSWYPIFASITIKTIIIRPLSSGFRDYLLADGVYIPTGAEDRTYLSNEESDEDDEGPSYTFPELDAQIRQAIALFGAVFPKLNWSSPKDAAWMLPRSSPLKCTSPADVYLLLKSSDFVNFDLDPVIVFEGCEADQEGKSMNYELELSLRKWYTFDTSREFRCFVRDNVLLGISQRDPNYYNFLNSSEIQVTVRNTIERLWRENLMMKCPVGSHYVFDVLLTRDFRRAHLIDINPFARRTDPLLFTYQELLDLAMGASYPPKIAVVNSQGHAEATRNAPAYQHNMLPFEALHFSAGRTPENFSDALAAEIIASQKEHDGRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQQ3</accession>
    <name>M5FQQ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_109981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626158.1">
        <property type="nucleotide sequence ID" value="XM_040768978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQQ3"/>
    <dbReference type="STRING" id="1858805.M5FQQ3"/>
    <dbReference type="GeneID" id="63684040"/>
    <dbReference type="HOGENOM" id="CLU_005533_0_1_1"/>
    <dbReference type="OMA" id="PLIVMCH"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="85"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="198"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="50665" checksum="B3A5A23168279306" modified="2013-05-29" version="1">MSELEALRSIINESLDILQDELKAANLPDLFVSKPEMHPLDDLTYLQTPRLFETRRILLGACRMLAAAVQPPTEKIIEEGWAHQRSQALHMACKYNVAGVLAQSAVDQDKGVDAETLAKRFGLSPDPFKREMRMLASHHYFRETSEGHFANNRISMSLVPPNVAPYGIEYIAVWGLKTAHCVVDSMPINEWRTGGQLAYGFDTDMFTFIAKHPEYLSMMVSAMSGLYESQANGLTTGRHFPWKDLPPGTVVVDVGGGEGGLMMAVGKAFPHLKVLDQDRPEVGPAALANWQKHAPELLAQGRISFEPHNFFQPQPRSGAEYVYVMRCIIHDWPHEESVTILNNLRNAMLPSSRLLIVEHVIYPPIMPKEKTPLLLANIDNNQPYKEISTPWPMPNGPQVLELAHDIEMFCNFKAKERTPAEWDSLLGECGLKVVKIWSTRTEFSIVEIMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR98</accession>
    <name>M5FR98_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624347.1">
        <property type="nucleotide sequence ID" value="XM_040774049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR98"/>
    <dbReference type="GeneID" id="63689111"/>
    <dbReference type="HOGENOM" id="CLU_2170986_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="110" mass="12046" checksum="767D19C10C8BD953" modified="2013-05-29" version="1">MWLAWFLQLSAGVVLCLLGFLGVGNQFQNPAQEETLLVYKLLHLSWLSASCFLPCTFSLWGFALLRFRALGLGIGELMGGQDTERILVPEDREMDGAAYGPDTTSFAEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRF0</accession>
    <name>M5FRF0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24952</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624457.1">
        <property type="nucleotide sequence ID" value="XM_040773931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRF0"/>
    <dbReference type="GeneID" id="63688993"/>
    <dbReference type="HOGENOM" id="CLU_1294368_0_0_1"/>
    <dbReference type="OrthoDB" id="2688393at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="213" mass="23889" checksum="2100E34DDBB9E9BF" modified="2013-05-29" version="1">MCGFMKAGDPTMTCGIYTTKTYDLIRHRVAHLYYECLVSELDEIPPGGGLVFGGFHVELPTCPTCGKTFTRYDSLQRHGKRTDTACFAPNFERYSGERENKVRRLEILRRELEKNVGMQYWINTPQPLPKTVKAKVGIRNGGPGLGSCVLEILSVEETYAPRYEFTTVKDGKELQVRLLDHNEPGGIPFYRPMKGSYDPNPNGKGLVLPPADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRL4</accession>
    <name>M5FRL4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_24403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625246.1">
        <property type="nucleotide sequence ID" value="XM_040773674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRL4"/>
    <dbReference type="STRING" id="1858805.M5FRL4"/>
    <dbReference type="GeneID" id="63688736"/>
    <dbReference type="HOGENOM" id="CLU_035750_4_0_1"/>
    <dbReference type="OMA" id="ICMLDHH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="29796" checksum="7606010F4D4F37A7" modified="2013-05-29" version="1">MSRSYDRALTVFSPDGHLFQVEYAAEAVRKGTCAVGVRGKDVVVLGVEKKSVLQLQDPRTVRKVVMLDDHVCLAFAGLTADGRVLIDKARIECQSHRLTVEDPVSIEYITRHIAGIQQRYTQSGGVRPFGISTLIVGFDPQGAQPKLYMTEPSGIYSAWKANAIGRSSKTVREFLEKNHKDDMSRDETIKLTIKSLLEVVQTGAKNIEISVMEGFNKISSLDLAQIEAIVAEIEREKEQEAERKRTRLAATAASQAAMSAAASGPEVPPPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR3</accession>
    <name>M5FRR3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626798.1">
        <property type="nucleotide sequence ID" value="XM_040770401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRR3"/>
    <dbReference type="GeneID" id="63685463"/>
    <dbReference type="HOGENOM" id="CLU_1348883_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="203" mass="21439" checksum="BF4512F10AEAAF60" modified="2013-05-29" version="1">MAIWVRSRLYLEAVEAVRVTVETVVVFEPINPAEVIVEALTTGHVSASLPTRARVRTTATHPSEDPCSVQGNTAQRRENGQVLGAENAPAAEGSADRRNTAGRRSANEVSGGMQSADTEARLHGGQQSTVAVVTINTVINSNIVDEHGKKNHSASTATDQTEAGQDDDNAHRTDSAVHQLSEQGHGRVGDGIVKEMSGLGQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS27</accession>
    <name>M5FS27_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627003.1">
        <property type="nucleotide sequence ID" value="XM_040768896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS27"/>
    <dbReference type="STRING" id="1858805.M5FS27"/>
    <dbReference type="GeneID" id="63683958"/>
    <dbReference type="HOGENOM" id="CLU_1652098_0_0_1"/>
    <dbReference type="OMA" id="YLARMNI"/>
    <dbReference type="OrthoDB" id="3203937at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="18351" checksum="D30386EFDC118AA6" modified="2013-05-29" version="1">MTGKHLSPDMQDVIVRMTLVLPVEEIVNYTGVAKHTVQQIIKYHHKFGTVALVPSKLVGRPPMLNEEDKAVLYSVIQRAPDQYLDELVDELQKLQNIKITEVMLSHYLARMNIIMKQIPKAALEQSKEKHAEFKYHMGLLYTPEQLVFVDESAGLFKEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSJ7</accession>
    <name>M5FSJ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625771.1">
        <property type="nucleotide sequence ID" value="XM_040773501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSJ7"/>
    <dbReference type="STRING" id="1858805.M5FSJ7"/>
    <dbReference type="GeneID" id="63688563"/>
    <dbReference type="HOGENOM" id="CLU_026663_1_0_1"/>
    <dbReference type="OMA" id="YRYKMEK"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:translation initiation factor activity"/>
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    </dbReference>
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        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="243"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="413" mass="46328" checksum="5399ECFFEC29811E" modified="2013-05-29" version="1">MAQAAGIVNIRRDVDDKFYRYRMPILLTKVEGKGNGIKTVLPNIPDVARALSRPPIYPTKYFGSELGAQTMYDSKADRFIVNGAHQSERLRELLDGFIDKYVLCGSCKNPETDLIVTKDEMIVRDCKACGQRTNVDMRHRLSSYIVKNPPKKSKKEKKGNGDAAANGKNGDADASPGDDGEGSDDELTKRINAEAAELPAVHEKSGLGDDWSADTSPEAVKARTASIEGAFKSSLVIGGDDDDEEAEDTDSPYYHLKTWLLENREDEDITSVDLYKKAQQLGIDKKYKTMQTIGEYLFSEDNPPVVPESKMIKRWTPAIKKLIIAMKDSDKAEKSLLGGLERYVGLDRPDLIPQVPKILMAWYLDDWIQEETVTQWGTHVSKKYVDKETSKKVRLAAKPFLKWLEEADDDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSZ6</accession>
    <name>M5FSZ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625352.1">
        <property type="nucleotide sequence ID" value="XM_040773703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSZ6"/>
    <dbReference type="GeneID" id="63688765"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_0_1"/>
    <dbReference type="OMA" id="WILATGM"/>
    <dbReference type="OrthoDB" id="3341077at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="38365" checksum="CE2390FE08CE6214" modified="2013-05-29" version="1">MVNIGIDEAAFFGIICLAFFYGIFFTLFCLAVYVLAYPQNGRRVNIPFLISTALFFCLITLYFIVRWMRAYVAFITSAQAQAGGAILFLEQVSEWHVAVSTSLWAVTGALADLMLIYRLWLVWDRSYYVVILPLIMCLGSLVTVFAVVYEVSHAELTTAYATAITNWAYSFLSLGLAQNFLVTGLIVLKIWKINMGVRGHTSTVASLWPVIAVLMESGALYSSCVMITLITYVTQNNGSAVMTDIIVPIIGITFMLIIVRVGLGFTKSRSNAMTSGQNYPSRSNAAGVMSSRRPQPNQSSNGLESGVDSDYPLHDIRVTLEREVIHEFGSDKEPSVLKSKEQDTDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT16</accession>
    <name>M5FT16_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626026.1">
        <property type="nucleotide sequence ID" value="XM_040773583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT16"/>
    <dbReference type="STRING" id="1858805.M5FT16"/>
    <dbReference type="GeneID" id="63688645"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OMA" id="AVHTEVW"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="47973" checksum="642AB018949EAA31" modified="2013-05-29" version="1">MGLGLSVFILGSALCGLAHSMNVLILARLLQGAGGGGSGLLGSIIISDVVPLRSRALLNGVSSVCWATGAGLGGVYGGLVADALGWRWAFLLQLPVLACVMAGLLWLVEYEVEGQEKGGKVWDAVKHRLDWWGSGLLVTSIGALVFALAFKTNESLPWSHPLVYLTLLLSLLSLILFVLVESRTSEPVLSLRLLRSVHIAAIAWSSFLASAATIALGLFFPMLLQIVRGNSASGAGMHLIPTTISGALGGVLSGFYIRTTGKYYHLIVLLCTLQALPCFLLALVGRHTWELLTWVVLMPQGFGGSGYNGSTFIAMLSSVRRADIALVTSIAFLFRSCGQVVGMALSSAIQQSVLERELEQRISGVDAGFIVAQVRRNASSILDLPMMQRASSLSSYATSLHAVFLANGLLALIATGLVLFMKEFPLAETLGEEMEDSKLEEAYEGEEMSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU11</accession>
    <name>M5FU11_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_55558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626551.1">
        <property type="nucleotide sequence ID" value="XM_040775334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU11"/>
    <dbReference type="STRING" id="1858805.M5FU11"/>
    <dbReference type="GeneID" id="63690396"/>
    <dbReference type="HOGENOM" id="CLU_079191_0_0_1"/>
    <dbReference type="OMA" id="CLMAYHN"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="70"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="8">
        <location>
            <begin position="157"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="23248" checksum="D8FE2E3EE1610DAF" modified="2013-05-29" version="1">MSTDPAQALLLECRRSTQTDTLVPYNAAVVTTIIRQIHTIHAHLVHSLRSAAPPGDELTPSPTPPPAVMFTSTHHHLQIRRLKRVLLVYHAHRLNMLRSMLHRAHLSVTHLLPTIRPLLSSSELTFIRTYAQIFMNYRAEFIDVLDIAAAVDEPPKGMWVNVRVVKEVGEVITEAGVVDFRKGGRYLVRRGDVEMLLVQGYLEVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU36</accession>
    <name>M5FU36_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPX2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_102794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPX2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623634.1">
        <property type="nucleotide sequence ID" value="XM_040767668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU36"/>
    <dbReference type="STRING" id="1858805.M5FU36"/>
    <dbReference type="GeneID" id="63682730"/>
    <dbReference type="HOGENOM" id="CLU_340991_0_0_1"/>
    <dbReference type="OMA" id="HEVPEWM"/>
    <dbReference type="OrthoDB" id="10674021at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027329">
        <property type="entry name" value="TPX2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06886">
        <property type="entry name" value="TPX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPX2 C-terminal" evidence="7">
        <location>
            <begin position="671"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="759"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="675"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="832" mass="91903" checksum="E5A6038C63850D29" modified="2013-05-29" version="1">MASNESSFAIPSQYLPPNTPSAAVDYEDDTPESSIALPNFGDATLLKDTKIPWGEEMSMFVPPFQQARKGKTVFKERVKKTGHTPIRKAEKLVKVASPAKAGKTSRQRSKSPRKRTMRNIDIIEDNDSDFMNYKKLNRDTGVQLQVETQNTGRGEETTQTESARKARRSRHQREEPLNPLPPILDNSESAPSSDLAPIHAAVDMFSPAVVTQTSVVRGKERKRSQPKASIEVAHDRKSLDTKHRDTSDLSAKPESARASTQLEQVAVLSTTEHRTPQLPFSPHPVHSRVHTPPVAAFFVPPPANLPMDETMPLPPPTPAAVRQEHRQSTAPAESSDDASFGGLMEKLKMYKERIGVVDGDAASSASSSTDSSSPEPAASPHEVETAALPVPQASDPVPLREIHAQPATVIQQSYPGQSLLEKLEAAARQTVRGVLPPSPAQPFLPPSPPAVQDPLPVARIAPEPPAPTNARKRVSSNDDKLSARPMKKPRQAKAGNKENVPAKPAPRKSPRKSPAKSRKRVVTKPPVLVETKPEPIHRAQTERKPERKVVTSANNVPRQPLERIKVLEEKKQALVESIQHRIPSTSFAPVLPPAVIEKHKQTFASTRAVWEQLATAAAAAAPVPPKPKKSNYHPAPNWTALHAQEDQRKARALAKQAQAHKPLPSQPFTSATELRAKEREEFERLIREKEELLSQLKEEKRLQQEMQEKEEVERLRRELDVKARERVHEVPEWMRKRKEELKASTIFLARGGPDLQMRDYTPPSAQHPLLHHPTSRQLESGNLAPKRRSNESTTLLTTGHGGHTNLACGTENYTAAQMWLSATLMHLGGGCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUA7</accession>
    <name>M5FUA7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_81334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626681.1">
        <property type="nucleotide sequence ID" value="XM_040776505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUA7"/>
    <dbReference type="STRING" id="1858805.M5FUA7"/>
    <dbReference type="GeneID" id="63691567"/>
    <dbReference type="HOGENOM" id="CLU_054590_2_3_1"/>
    <dbReference type="OMA" id="IKHREAV"/>
    <dbReference type="OrthoDB" id="10019231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29314" checksum="F30AECA3F801E58A" modified="2013-05-29" version="1">MPAELSPCCVSGHLHEGTPTGVIEKITGFDVYITKPDSGSKAKTILFITDVFGWNTPNARLLADEYAKAGFYVYVPDFFRGDNIPHDMLQTIAPREPHNRSAAQVASDNTQTTATFGPWVTKHNEAEIKPLIDEFLKYLRADPLTGKIGAVGFCWGGKYSLLLAGEGSVDAAVANHPSLTTQEDYVSINKPTQINVGTNDIFLTNESVEQAKKGMLEQKADIPFEINVYQDAVHGFTVRGDISNLKEKENKEASANATIRWFGKYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUW8</accession>
    <name>M5FUW8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626227.1">
        <property type="nucleotide sequence ID" value="XM_040768988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUW8"/>
    <dbReference type="GeneID" id="63684050"/>
    <dbReference type="HOGENOM" id="CLU_2687789_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="8167" checksum="60C50D9EFC85A96D" modified="2013-05-29" version="1">MGVDHRNNCLELENSHIVMVGGTLQSSRGNGFMGRTPMFPAEPNGLVCLPPAYSWNLLGQHRLTKSAHLRVPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV46</accession>
    <name>M5FV46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_95867</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627026.1">
        <property type="nucleotide sequence ID" value="XM_040777325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV46"/>
    <dbReference type="STRING" id="1858805.M5FV46"/>
    <dbReference type="GeneID" id="63692387"/>
    <dbReference type="HOGENOM" id="CLU_011072_5_0_1"/>
    <dbReference type="OMA" id="VNKADMM"/>
    <dbReference type="OrthoDB" id="61815at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="183"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="602"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="693"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="621"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="698"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="716" mass="79412" checksum="43D19372E6DB2C0B" modified="2013-05-29" version="1">MGRSQNINPHSSDEAHSMPAKSKKENHGLGRAIINKKAKDAKQAHENGDLYTTDFEKYSRLNSVTQQGDLDEFLNTAQLAGTEFVAEKQNIRIMQSPSAASSSAHNPFLLSAAEEREARRLHQENKALLRVPRRPPWTKSTPHAQLERQEKDAFLMWRRSLANLTESNPNLLLTPFERNIELWRQLWRVLERSHLIVQIVDARNPLAFRCEDLESYVQDVEGPEGEKGGRKGMRNSLLLVNKSDLLTAQQRQAWADYFEGQGIKFAFFSAADAAALQEAARVEALDVEEMHESSSDEEDDEDNEESVDDKYGAEDDIEDINPDADFQVESRLAADLEAATKLEGKVEAPHSAGVPEETASSADEVEHFEENEDEQVAKDPRIRVLDVTELEDLFVREAPDLTLFATESVPTPRLTVGLVGYPNVGKSSTINALIGAKKVSVSSTPGKTKHFQTIHLSPDLILCDCPGLVFPQFANTKAELVCDGVLPIDQIREWSAPVQLVVSRVPRQILEGTYGIVMRTPAEEEGVREANAEDLLVPYAIARGFARAGKGEPDESRAARYILKDYVNTKLLYCHPPVGIDSDEFNSPSRALEIRRLEKLGKKKAPTTRVGKDSDAFIPSPGQSSTGGTDNMSQPSAHKSDALDREFFNTNAMGNRPYMNGRGSRPMPHQRLVADDGRTLTAQEQKLAALGYGLGAGSKKHKLPKRTKQRSGKGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVE1</accession>
    <name>M5FVE1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_109677</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626477.1">
        <property type="nucleotide sequence ID" value="XM_040768924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVE1"/>
    <dbReference type="STRING" id="1858805.M5FVE1"/>
    <dbReference type="GeneID" id="63683986"/>
    <dbReference type="HOGENOM" id="CLU_000315_10_1_1"/>
    <dbReference type="OMA" id="KCQTHEL"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18004">
        <property type="entry name" value="DEXHc_RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000020">
        <property type="entry name" value="DNA repair and recombination protein RAD54B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="394"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="732"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="922"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="922"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1072" mass="119117" checksum="DDD2D4943924B722" modified="2013-05-29" version="1">MSTYKSLIPSKRKSDENVESLIFKKPVTGRNPLGVLVANSVPYQLANTPSTSGEEETYWNVVWRKPQFKKNKTWDGDGVLVVCGSKMTLRDQDNKIISTGVISQRTGVIEPGASLSVGGKDIEIDTAIQKEEYLSGRCFGSSSTSFIPLPPPSKGFQAPKPLARTSVGGSSKPAAPLGAKLAIPTRKPTIMESKNSVKPMDHPTDADYKVVRYYTVNWRKPQTKKHKTWDGDAYLVVTGTRGVMQEAGGRILGTATWDAAWLEGSLMFIGGKEVEIDNLITEAEFHQQCSGLPPPEPEPEGPRHSPSVPKHHSPVIKVGAPRARTNFTPKVDGPLHDPDQAGALVLPRPTPAHQTRAGKSGYTIEDVVVDPVLATKLRPHQREGVIFMYEAVMGMRRHEGFGAILADEMGLGKTLQASSNKTIALLWTLLRQTPYRPREPIYHHKGEIGKAMIVCPVSLVGNWRSEIWKWLGRDRMGVFVAEETNKIKQFLNSRGHDVLIIGYEKLRSVIDMLVYSDPMIDLIICDEGHRLKSSNNKTSQMFTALKTKRRIILSGTPIQNDLSEFWSMAEFCNPGLLGQYNDFKRIYEQPIVRARAPNCTEKNKEIGEARSSQLSSTAKSFVLRRTADILTSYLPPKYEYVAFIRPTKVQIDLMQRVLTSQAIGRALRNGMAQALEMMSILGKICTSPVLLKTTAKPPSQWAPEYQEIVSRLPRHMEESDSSFSGKLIALMNLLDAVRKITEEKVIVVSQFTKTLDVVEAICTKMRWTRERLDGTTPQNERDSRVQTFNRTNQAECFIFLLSLKAGGVGLNLVGASRLILLDSSWNPAHDLQAMARIHRDGQKRPVHIYRFLTVGTIDEKVYMRQVIKTGLTLMAGDGDGKAKGDSFTHDELRDLFRIHTHTPCHTHDLLDCDCAASRLVNDEGDTSDGEEKEEKDDEQGVLDEDTVSEAPHRGFMLASQVEIADITARAKKMKKDLAILDEWTHVNCMGPAGRLSIKDPVLRDVIRGVYDKQTPAETGEGESSRGSKILTEIDMDKIQASSDSDDGGQNRLTNMDGVPEGAVTFLFTKCSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVV4</accession>
    <name>M5FVV4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627386.1">
        <property type="nucleotide sequence ID" value="XM_040770300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVV4"/>
    <dbReference type="STRING" id="1858805.M5FVV4"/>
    <dbReference type="GeneID" id="63685362"/>
    <dbReference type="HOGENOM" id="CLU_008053_1_0_1"/>
    <dbReference type="OMA" id="FHAKYMV"/>
    <dbReference type="OrthoDB" id="9997422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030572">
        <property type="term" value="F:phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00138">
        <property type="entry name" value="PLDc_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF22">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="871" mass="97813" checksum="4E398465E46933A7" modified="2013-05-29" version="1">MVNQRVVDLCHKEETVTSYLHKHPNKAPHKIPRKLFPKPNLFKRLFFRYEVKRELHHGQGELTEEMLDRVATCGKFQKRPSDLFLKMYADVLLCLERDPMSGLVSPPLLGSTGVIPLSIISVIPDIMQHYYDVIVRAEREVILATNYWQPSRSVTKIREALRQLSKNAGEKKRKVIVKLMYDRGALRQFVHNHTPVPAAGWKAVDLPEAAEIPNIQMEVINFHRPLLGTFHSKYLIVDRKVALLNSNNIQDRPNMEMMVHLEGPVVDSLFDMAMLSWNNALRPPLPSLLKQIGDASLPAPARRYLFGKKNPYIACKDIEGASRRARGDLRRQHTELLEELERERQQRMHNRGAELWDTVREAFHVNASPTDPTMAPRSRGADLWDSVREAFQQSPVTAEPSRGWNMRDTLLRRNPSEERMPSRGFTWSWSRDPTAAGPRRPATLHHVNMPTEPLVLNNLDAPMVDSPTEMRSRAHSLHENQRNATEKTPALEGSTAAVPHTQNGSPTSLSPSPEKLVPLRSDGAANIKTISDPGPARFATTEVLSNIPGGHVDAVMLHDSPDHATGENSALHVSVQNPHDSHLTSRANSFDSVLVRHTSLAKVAAHLNLGNNCEVDPTATELDGDFKPHILHKPHDPVPIAMVSRRPHGAPGHKDIRTPQNAAWLGAFRYAQRKVIIQTPTFNAAPVVAAALSACRRGVEVVLFLDLGFNDQGEMIPGQGGTNEQVVFKMYRILKEEGQTHEKNLKVYWYTGKDQIKPMNARVKQRNCHVKFCAVDDQVGIVGNGNQDTQSWFHSQEINIMVDSPAIVEEWLNGLDTNQNTLAFGLVDDDGIWRYRDGEKKGQPLEDLGGLKSGLFTSLREAIRMVQKARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVZ9</accession>
    <name>M5FVZ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628933.1">
        <property type="nucleotide sequence ID" value="XM_040772789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVZ9"/>
    <dbReference type="GeneID" id="63687851"/>
    <dbReference type="HOGENOM" id="CLU_1992558_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="125" mass="14249" checksum="A7AAA1BD1DB683D1" modified="2013-05-29" version="1">MVIDRLQTPNEMRTMMFLLQGPAYDDAKLSPCESVRSRPSHPRPELPNALEPQPRPPLTHRGSRPPPDHIAHDHKLVLVPRQIERMHTLSSVRRSTLYMLRTTLYSLSCELVRDCTEGDEPACSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW24</accession>
    <name>M5FW24_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_88590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628963.1">
        <property type="nucleotide sequence ID" value="XM_040776866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW24"/>
    <dbReference type="GeneID" id="63691928"/>
    <dbReference type="HOGENOM" id="CLU_2333574_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="10304" checksum="1C0A59DABA33535C" modified="2013-05-29" version="1">MKSNLHENLQQAGLLFGGASWVGTAPWCKGECAVGEVEAAVAPSGQFTHCASLSNFGGDCYIGEKALCTSQYSSSRLVHFVCALGYPSIPVPGWTYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXG7</accession>
    <name>M5FXG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628066.1">
        <property type="nucleotide sequence ID" value="XM_040768664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXG7"/>
    <dbReference type="GeneID" id="63683726"/>
    <dbReference type="HOGENOM" id="CLU_2049625_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="120" mass="13262" checksum="9C62B3E1C6DF34F8" modified="2013-05-29" version="1">MLILTSSERTPHVHRTLDTSKVVLYRLSPHTSSNTPPPPYLSRCPSFYKLPSDAPPPYPYSDAKHPACFGQADADELARKLSQLTMVAPTPMPSTCPTRPTVAPRRPKPRSLRVCNPDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXU2</accession>
    <name>M5FXU2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628221.1">
        <property type="nucleotide sequence ID" value="XM_040768552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXU2"/>
    <dbReference type="STRING" id="1858805.M5FXU2"/>
    <dbReference type="GeneID" id="63683614"/>
    <dbReference type="HOGENOM" id="CLU_490907_0_0_1"/>
    <dbReference type="OrthoDB" id="3543113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="61665" checksum="9DC23971F143C40F" modified="2013-05-29" version="1">MHAVFRLPELFEVVCAHGTPSTLAALARTSSALFLPAVSELYRNAGYQQLFHMVWVYLQRQQKQHVEGWDTMQHDTMPAWRRFQIYAPLIWHLSIVGDMWNALLKGTHGGNVAYTPEKLLLYLSSIASVSDLHPVFPNLRSLKIDPVKTQPLGSLIILLSGNLTSLVTVHLNLASAIAKPDVAAMLDILPDRAPVLKCLELVGAVSDAQELSLSITRMIQAFPQLEELSCGTACLQAGILLGLSKLSNLRSIRIIGTLLVPTRIPTKMPGSRHLHEPLPSLRVIHIEEVASSMAGPLLSQLGTPSVEAVTVNLSSNESSPFPDEIKALFLAVSRFTSLRDFSISARGQGPRGHSAAFWQYGSILFTCSRLQKCVLRNWLFPASPVDDELIESMAMAWPDLQALSLQWNVGKNDVLSTPTLNSLAVLFNHCPRLTHLQLWSLSAPVGRTPVVDSCLQPRPLWLGVRHNNIEDVDDASIFFVTLTSALEVYMESSPEAFAWWDDFDTTPWNNIILRMRTLRRYIQMQADKKGTAFDNRMDNFTLESGHNCPPAPVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYC6</accession>
    <name>M5FYC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_106234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629950.1">
        <property type="nucleotide sequence ID" value="XM_040768227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYC6"/>
    <dbReference type="GeneID" id="63683289"/>
    <dbReference type="HOGENOM" id="CLU_1570599_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="19481" checksum="940A4BC75668C078" modified="2013-05-29" version="1">MSQPSVNSIGASKDEGNPSAADVSPDNRTAHGAKISRDFLKRMPTPRRIERFRAELLQQNEALASRLELESAEIEADEKRLRKRKHRFETESIRKKQCEEKLKSLDEGLEGIIKYKKASSIFRAKETGREENFEDDEQVEENDDGETDFPPLESEEERSPSSSVQQRCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYE9</accession>
    <name>M5FYE9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Halotolerance protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_53532</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627772.1">
        <property type="nucleotide sequence ID" value="XM_040775179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYE9"/>
    <dbReference type="STRING" id="1858805.M5FYE9"/>
    <dbReference type="GeneID" id="63690241"/>
    <dbReference type="HOGENOM" id="CLU_000288_127_2_1"/>
    <dbReference type="OMA" id="VIYMFMR"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000183">
        <property type="entry name" value="Serine/threonine-protein kinase hal4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="113"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00078109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU00875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="414" mass="46067" checksum="286860DF6137F7B0" modified="2013-05-29" version="1">MEEDSQTSSHDHVRAWREGSALPQGAPPSRPPSRAPSVRSGREPSVPRQEKHKPESVFTLAGLIGSGPKLSRRPSQSSRKSDSERGAPSAYGPPGPVGLSTDSVASLTKKYGYCEKVAIGKGATSVVRLAHKWERGSEEKLYAVKEFRKRRKNETEKEYVKKLTAEFCISSTLHHINVVETVDLVQDEQHHWCEVMEYCAGGDLYAAIKKGGMSREEVECCFGQILRGVNYLHSQGVAHRDIKPENLYFNAKGHVKIGDYGASTVYRLPWEATIHMSTGLCGSEPYIAPEQFLNKPYDARLVDIWACAIVFYCLHFQELPWRVAQLTDPLYAAYSAACLSSSSNNPSSLPPTVSLLSPRACRPLLRKMLEPDPKQRALIEDCLRDQWFVNVEVCTEPLREGSKGHRHVLPGLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYK3</accession>
    <name>M5FYK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_22672</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628496.1">
        <property type="nucleotide sequence ID" value="XM_040772917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYK3"/>
    <dbReference type="STRING" id="1858805.M5FYK3"/>
    <dbReference type="GeneID" id="63687979"/>
    <dbReference type="HOGENOM" id="CLU_015166_16_0_1"/>
    <dbReference type="OMA" id="NWAVGIP"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015227">
        <property type="term" value="F:O-acyl-L-carnitine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902603">
        <property type="term" value="P:carnitine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="17"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="115"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="214"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="304" mass="32227" checksum="BFF7FEE8ADFBE343" modified="2013-05-29" version="1">MSDKAGESTPRVKNELLDNIKSFVAGGFGGVAAVLVGHPFDLVKVRLQSAAPGTYTGAVDVVRKAIAKDGMTGLYRGMGPPLLGVTPIFAISFWSYDVGKKIVYAATPNRKDRTLTTAELAFAGFFSAIPTTLVMAPMERIKVVLQVQGQGAGTHYTGPVDVVRHLYREGGMRSLFRGTWATLARDGPGSAAYFVAYELVKKAMTPAGSDPSQLHLGSIVFAGGMAGVAMWTIAIPPDTIKSRLQSAPHGTYTGIVDCTRKLIAQDGVAALWKGLGPAMARAFPANAATFVGVEVSRNLMDRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR7</accession>
    <name>M5FZR7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630410.1">
        <property type="nucleotide sequence ID" value="XM_040772222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR7"/>
    <dbReference type="GeneID" id="63687284"/>
    <dbReference type="HOGENOM" id="CLU_2812281_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="67" mass="7277" checksum="D44E63AE7A4116DD" modified="2013-05-29" version="1">MATAATAAAAGFLVYLFLSWSWPFGSSLGAGMHRGFPSLFLHFYAFVRLRCLPFAQVLAMSLGSGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX5</accession>
    <name>M5FZX5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626009.1">
        <property type="nucleotide sequence ID" value="XM_040773578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX5"/>
    <dbReference type="GeneID" id="63688640"/>
    <dbReference type="HOGENOM" id="CLU_1626990_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="18541" checksum="8C511A4849C58A4F" modified="2013-05-29" version="1">MRDPQLWERALTPDGRENPPNPWAVGFDPDEPRYPPMSNSPFLAPTHTAPAAGAARRELTQQQSHRLDVGGAKGKEVEGFLQRQPRVLDTDLAAGWQARTRQSEGSGAEGVLLPDMSEEDDRTYDDGKRRFTFPVHQFVFYDPKMKAKMFPDRRPHPKGFKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZZ5</accession>
    <name>M5FZZ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_95084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628367.1">
        <property type="nucleotide sequence ID" value="XM_040777270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZZ5"/>
    <dbReference type="STRING" id="1858805.M5FZZ5"/>
    <dbReference type="GeneID" id="63692332"/>
    <dbReference type="HOGENOM" id="CLU_065200_0_2_1"/>
    <dbReference type="OMA" id="IKREEAY"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="238" mass="27504" checksum="8C4AE901DF6BD6EF" modified="2013-05-29" version="1">MDAHLDPSLEPHGDIPNTPLAVSLISFFLGAVFCAGLALLAAPPNYWWAGRELGFYIACWAGFHWGEFAVTAEWNKSRLTVDSFLLNNFAEYHYAHGVALFEYFVERWFWPGMKQHWQLSVLGMVITLLGQALRSMAMVHAAGNFSHWVETRRTQGHELVTTGVYAWIRHPSYAGFFYWALGTQIAMLSPVSFVGFWGIMYWFFSKRIRVEERFLVFFFGDEYRTYRQRVGSGVPFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G010</accession>
    <name>M5G010_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">XPG I-region protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_93912</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPG/RAD2 endonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630495.1">
        <property type="nucleotide sequence ID" value="XM_040777183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G010"/>
    <dbReference type="STRING" id="1858805.M5G010"/>
    <dbReference type="GeneID" id="63692245"/>
    <dbReference type="HOGENOM" id="CLU_378548_0_0_1"/>
    <dbReference type="OMA" id="RFYQTKV"/>
    <dbReference type="OrthoDB" id="17262at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09858">
        <property type="entry name" value="PIN_MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022039">
        <property type="entry name" value="MKT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022040">
        <property type="entry name" value="MKT1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF32">
        <property type="entry name" value="POST-TRANSCRIPTIONAL REGULATOR MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12246">
        <property type="entry name" value="MKT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12247">
        <property type="entry name" value="MKT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Post-transcriptional regulator MKT1 N-terminal" evidence="5">
        <location>
            <begin position="352"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Post-transcriptional regulator MKT1 C-terminal" evidence="4">
        <location>
            <begin position="538"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="794" mass="88794" checksum="D31BD32D6DDC223B" modified="2013-05-29" version="1">MPVRHLDAYLTDRQQVHTLPLSALTETRLGIDASLYLARLLQNPKTREPFLPATGGLPLSLTQRIETDLRILEKLRIKPVFVFPGIWPNSAKKGAPGKYPNQAVHFSPLVNAAQFDMMRARSEAWDLYEKGKVAEATTAFETKPASHVVQWDLWRAVLRIFRHRNVDFMIAPYTASAQLIYLYRHPKSYVHAIWGATETLLYNGVDKLILSVMFGSQTFAYCTKSAILADMNLTPTQFLDVGVLAGFDDLIAPPFPPTQNDMTLKPVLDMVKFYKSGHAAASAFFHDPQVKATQYIDTFARARAIITFALVLSSDGVVAPLTLTQSPTNPATPAKNADPSVAPQVTTAADLPQDLHDIFTHRLPDEVYYYLSRGLVSPQPLNWLTSGHISEPPPLDNGENSEYRRFVKEVISEGATCPRAVSLALLSSSINSWWASRKVTSSYWYDAAVPPQPGRHDKFVPHSGKDTLMQIERCVTWWNVPNFIVEEELRRQNSSTIDFQLCLGATSQEKLAGRTRAKANHAHPLDKKDEVVANVVWRFLELRGFLSSATHMHTPLGRSMHSSLKASRVNDKFQEPLYLFLELVRAGVMHGNLWSGRAYSGGPSFGDEAEKRSMLLVMRVLSIVPLNFKQEPWKGPLSRELLVFNSFLHSLSRALRSLVELTAMNMLLHGDARRARDDLLDIALSLPFQADVNTGFGILGKTYLDALVALKGGRVEESEKDDEEVKEAKEQALNICDENFDNIKSPSSEVERGFRFWDAAYAAIKSLEAANEAVSPELVSEFDAAQAWLHPMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G056</accession>
    <name>M5G056_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626079.1">
        <property type="nucleotide sequence ID" value="XM_040768964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G056"/>
    <dbReference type="GeneID" id="63684026"/>
    <dbReference type="HOGENOM" id="CLU_1722308_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="17258" checksum="17FF01F2BA728453" modified="2013-05-29" version="1">MNDESHLQWIERVTTDEDPSTSPTEALMRLDLRILKTTHTESVSSWNTFRPLRPGENVCAVNIIPCDTVSVLEDETTFGDKLFRRQSHESRREDELKRAMRELNAVDNEGNEVLLVSRGSEVSRVPIHPTSESFDLPPRDAPPLPHRLGVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G060</accession>
    <name>M5G060_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar membrane-associated protein IML1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Vacuolar membrane-associated protein iml1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_80132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IML1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628437.1">
        <property type="nucleotide sequence ID" value="XM_040776428.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G060"/>
    <dbReference type="GeneID" id="63691490"/>
    <dbReference type="HOGENOM" id="CLU_000935_1_0_1"/>
    <dbReference type="OMA" id="SWMNATP"/>
    <dbReference type="OrthoDB" id="39497at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04449">
        <property type="entry name" value="DEP_DEPDC5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045838">
        <property type="entry name" value="DEPDC5_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027244">
        <property type="entry name" value="IML1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048255">
        <property type="entry name" value="IML1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179">
        <property type="entry name" value="DEP DOMAIN CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179:SF8">
        <property type="entry name" value="GATOR COMPLEX PROTEIN DEPDC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19418">
        <property type="entry name" value="DEPDC5_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12257">
        <property type="entry name" value="IML1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEP" evidence="6">
        <location>
            <begin position="1115"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="502"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="612"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="671"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1087"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="562"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="671"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1482" mass="167628" checksum="D8D9AC555C334246" modified="2013-05-29" version="1">MHTMTAGTMQISISADIAPAFGFKNRSSVIVTKVDQDAHTAEHIELCFRDQYLGRSEMWRLGMSLEDTCVHSAQTVNFATCIEAQIQGIFVRGMRVHSAYVTALTKTIYRSLSARHTLLIQISKELWEFAEDGERYYEKLCSSFLPELFSHWRAANAHHLLSVVLVSRVWYDDAELKYATGPIRRCKTTDRAYKDLYKVIIDLEIMEEWESTLVSLKQSLWDFQREILLQHIAPSEASPRKDTLEAVLIGRISNAHEGNILEALNLALNPFEKYHVDRDMGRTGLSISVVTPGTGRFEVGKELLRLTNERMNFNGFTVDLVCLTHRPLHAVPLFSYMSEVPEQEHPLSQREMNPLYYENSSKSRTVMPPEEVLIPPEEEVIAPKEVLQYHMIPSWVYCSYWERSWDMPFRTDRFIPRCRIYEIQMLGLLEQDISSTISIPFLDEDASLMFGPKTTSDGKDRKAAKERARRNFARNVFGRKPIEIPPPPFIVGYNSGSTLSAASRSSVRMPPGVLKMPPLMPVEDPPRGRPTRVTPLTPSSEVPPTEKPPELIKPGTSPSKPSIISTRSAASATGSDSLGPLPPRQPRMFSASWLLSSLRVQPALPQTTSVTVIRQSPSAPTKALETAAPPAVTAPEVPPAILHPMKKDIPIKDMKPLTTAGASPVPISIKARQQSISRPTRPTSELYADPPLIHPARASLPRNSLPADAPMSYKGGSAEASGSTPQARYRQISTGVTLLNPSNPKPEQLAESAQEARRWKYSFAQPTFEHQMKWQSLCMPACLPLTVDVYPRQDELDNDFRTYHHTILVPDANSQFIRPPKYKKEGYTPETYQAEQLLRAIASFRLAQGFQFVVAPIRTGRKHTPVLMQNRLSGSFGRTGLLEPTTSHANDISLELKMGGASEVLRNVGDAPIYLSMGNQLHRISYDKEVQEIKVTAYIRGRQREEVLSYECLIWPKHGSGYMKAEAHFNYPAEHIGWNRMDMLLAGAPSPPADRMRYWRTRFVVIPSQDELQPRFEPGPTGAQLSNEEVRIQGMEHFAELFGRLRWRPDDVHNDPNTSVPLLITYLDPLACLLDEPLMEALAEAHMPASDRKRKSEKSIEGSSLQSIARAMRDPEGGLVIEDHKWHNNLHKDSFSGSDFVSFLFREYRDVSTREDAADWGNKLMDQGLIEHCRAYHMFLDGHYYYRLTGEYAASSQTKRQRIWFNRHTPSRDIRKGNSPAKRQELILTQSITLDLDPMKHSDQAELVMLHHDVIHNPDNAFHFEMNWIGTTARYIDDIVWSWARDVEEFGLKLVEAYVDQVSDISTHSPFQSCISIPLAVAPPVVPDLARRLPVGANPGLYFEAALLRELGYILDIESISRYPEQVTVKYSYRHSPYTYPQYIHSSGLAFVQVVGGTDGFQWLANGLAIASAVTRRLKQKQWDAPYAFRDESPQPARVAEGIRLQLQEFCADADKLKMFWDKVVDGLPPVKEEHEELLLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G079</accession>
    <name>M5G079_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PQ-loop-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_77358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630555.1">
        <property type="nucleotide sequence ID" value="XM_040776264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G079"/>
    <dbReference type="GeneID" id="63691326"/>
    <dbReference type="HOGENOM" id="CLU_040201_0_0_1"/>
    <dbReference type="OMA" id="AMAYAYM"/>
    <dbReference type="OrthoDB" id="407617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF37">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="303" mass="33120" checksum="5ED24BB111A8215C" modified="2013-05-29" version="1">MPVNPVLENVFGTLGTVCWCVLFVPQAWKSWRDKSTYGLSPLMVLLWSSCALPLGVYNIASSANIPLILQPQLFGTVGAICWVQCLYYEKHISFERSLLILVAFLAVIGGLQVAFVFAVRHALAEGNERPLQFFGVMTVVTIYAGVIPQLYEIWKIKEVAGLSLVFMIVDILGGVFSTLSLVFNKSIDPLLAFSYISVIVLNSFIILLYIILNPLAARRRQREAVMAGVSSTSPVIGNSSEKNEGAYPQPQILSDASLNAEVETGTHLTVVDILGEQTPEEPGKEENAEEYCGQKANEVCSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G093</accession>
    <name>M5G093_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630565.1">
        <property type="nucleotide sequence ID" value="XM_040768151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G093"/>
    <dbReference type="GeneID" id="63683213"/>
    <dbReference type="HOGENOM" id="CLU_1906661_0_0_1"/>
    <dbReference type="OrthoDB" id="5946233at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="15063" checksum="AAA8CCEF7E99B003" modified="2013-05-29" version="1">MKYAPASHLVFELVPEHFHLEMDRLYQALGAPKVTMGNFWTIYQELLEGCVQSAMLSLPLLSARAEEELQMLNKYMDLCPHEVDDETDEDDGACVLGGGYYDALQGIEEPGNTVMWDLEDLLHVRVHPVLVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G118</accession>
    <name>M5G118_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_22070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629328.1">
        <property type="nucleotide sequence ID" value="XM_040772662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G118"/>
    <dbReference type="STRING" id="1858805.M5G118"/>
    <dbReference type="GeneID" id="63687724"/>
    <dbReference type="HOGENOM" id="CLU_022332_0_0_1"/>
    <dbReference type="OMA" id="IWICLSS"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="55"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="37991" checksum="671360C65933E2EB" modified="2013-05-29" version="1">MATQKDVEASIPPYDREHSEHKEDLEVKSKLDDDLDLLPTTQPTAKPQEKKKLSAAVIIPIWIVLSSSVIIYNKYLFSVLDFQYPVFLTTFHLAFATVGTRVLQRTTNLLDGAKEVHLTREMFVRSILPIGVLFSGSLICSNVAYLSLSVSFIQMLKAFNPVAILLISFTFRLQDPSRRLIAIVFMISGGVALASYGELHFELFGFICQAFAVIFESCRLVLIEVLLKGLKMDPLVSLHYYAPVCASINALVIPFTEGLAPFRALYQLGPLVLITNAMVAFSLNVAAVFLISAGGGLVLTLAGVFKDILLITGSVIIFASPITPIQIIGYSIALGGLILFRTTSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G159</accession>
    <name>M5G159_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_14213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630870.1">
        <property type="nucleotide sequence ID" value="XM_040771023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G159"/>
    <dbReference type="STRING" id="1858805.M5G159"/>
    <dbReference type="GeneID" id="63686085"/>
    <dbReference type="HOGENOM" id="CLU_001724_12_1_1"/>
    <dbReference type="OMA" id="DMYDYER"/>
    <dbReference type="OrthoDB" id="2751550at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080043">
        <property type="term" value="F:quercetin 3-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080044">
        <property type="term" value="F:quercetin 7-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF1494">
        <property type="entry name" value="FLAVONOL 3-O-GLUCOSYLTRANSFERASE UGT76E12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="58841" checksum="E725498F3CF958C8" modified="2013-05-29" version="1">MTARSAIFNGDRWLPSCQVDFVKRAKDEMSRQCISEEERNSLLSRVRVIAYGDPQPVITPELAQILLSMDPREVHDPPLKTCADGVHMINKLMDGQTFIDKLGQEWGPVGAVPKILVADLVMGNIVLPVKEKYNIWVFVWWAGSIGSFTRAFAPLKHGGRTEGYSDECEAIFAEPERRNGRSFREIALDMGIRDHRASDNFVRLAGMPPYFQWEDYPQPVWLIAVYNILIGGKKLVDAADGFLMTTLEELEPEGHKDMIQWARRHRVLCLGPQLPVALFSQDSQTSAEALAKLDVNYNAVPAASVANQNGNHMTTVGINGHVSVDPAIAFLDRSLAEYGQHSAIYVSFGSLLSPHEAHMKILIETLLALEKPMPFIITNASGSLSDDLKVATEKSGRGLVVAWAPQQAMLSHPISVIYVGLGWMITHCGGGGMFESLSSGMPVIAWPFMGDEPQHALWISQVLDTGFELLQVRTGVPGKPGLRNGTSIPILGTAEAIRTELHETLQRAQGKDGARKRENAQKFKNMISNAVKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1B3</accession>
    <name>M5G1B3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_58917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624455.1">
        <property type="nucleotide sequence ID" value="XM_040775527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1B3"/>
    <dbReference type="GeneID" id="63690589"/>
    <dbReference type="HOGENOM" id="CLU_1880333_0_0_1"/>
    <dbReference type="OMA" id="KEWIRAY"/>
    <dbReference type="OrthoDB" id="3219854at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="14976" checksum="477EB3B68D5F495E" modified="2013-05-29" version="1" fragment="single">MSAGSTGSAPEPFAVPDPQEASNSILWMNGLWLTSLVVALYTAVLAMLVKEWIRAYDAHCSASAEPHIQARQRHFRHLGFVAWKVQDVAESLPLYLHVAVLCFLAGLTVYLWELHTTLAILMTVLTAGGYSGYFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1D6</accession>
    <name>M5G1D6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_105111</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630940.1">
        <property type="nucleotide sequence ID" value="XM_040768040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1D6"/>
    <dbReference type="STRING" id="1858805.M5G1D6"/>
    <dbReference type="GeneID" id="63683102"/>
    <dbReference type="HOGENOM" id="CLU_007727_4_3_1"/>
    <dbReference type="OMA" id="CFVSPAC"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000005">
        <property type="entry name" value="histone deacetylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019154">
        <property type="entry name" value="Arb2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09757">
        <property type="entry name" value="Arb2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="57"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Arb2-like" evidence="13">
        <location>
            <begin position="414"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="671"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="671"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="697" mass="77464" checksum="671D384D6257782C" modified="2013-05-29" version="1">MALSDEVVGLRPRASSVPPESSRGLFIRHEPNRTGYIYDTRMMAHNDGMTEEQEDRHPEGPRRISVIFNALEKKGIIQRMRRLQIREATRDEILFVHPPSLLAKMDQMEAMLIGEGKDAALAGTQGYYETLSLYVHPSTAYCARLSCGGVIESTMAVAQGTVRNSFAIVRPPGHHAEPEEHMGFCFYNNVAVAVRVVQSRTSIRKVLILDWDVHHGNGTQAAFYDDPDVLYISIHRYEGGNFYPGGTGGGVDKCGSGAGKGRNVNIPWPSGGRTDGDYIHAFQKIVIPIAYEFGPELVIISAGFDAAEGDQLGGCFVSPACYAHMTHMLSALAGGKLVVALEGGYSLKALSQSALAVGETLVGDHPPELPPVVPSDVGTETVWQVASYQSQYWNSINPKAIEPRPVDLDTFSVSQLLRAHREMDLASQYNMLRVPLAHPDLRARFDHQVLATPYLLDPNTETIVLFVHDFGNLRVELQSPLRVDVRMEHSYLIDSSRRVVEWANERRYGLIDINILMHHIVEAEEVINPIVTPQDEKRLLRTLVVYLWDNYMDLSAAKNFIIIGHGSACQSVIGLLNDRKPYLDKRTKAVVQINGMNTIPTVPKDDDDLRRWYSKKSIVVLPARHPLARDPSMALKRHGRLLPCGEEKAIKVLDWAVSHVLKAIVDPRINPISSQDNQSKSHTNTSVMNGDADIEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1G9</accession>
    <name>M5G1G9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">DACRYDRAFT_107768</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="19">Forms DNA polymerase zeta with REV7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628947.1">
        <property type="nucleotide sequence ID" value="XM_040768527.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G1G9"/>
    <dbReference type="GeneID" id="63683589"/>
    <dbReference type="HOGENOM" id="CLU_000203_3_1_1"/>
    <dbReference type="OMA" id="GRNKMGF"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:nucleotide binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:DNA replication"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:double-strand break repair via homologous recombination"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="POLBc_zeta"/>
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        <property type="entry name" value="DNA polymerase"/>
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        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="3.30.420.10:FF:000024">
        <property type="entry name" value="DNA polymerase zeta catalytic subunit"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
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        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
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        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
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    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
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        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13 20" id="KW-0408">Iron</keyword>
    <keyword evidence="14 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="26">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="58"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="759"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="1002"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="1501"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="422"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
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            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
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            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
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            <dbReference type="ARBA" id="ARBA00049244"/>
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    </evidence>
    <evidence type="ECO:0000256" key="19">
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            <dbReference type="ARBA" id="ARBA00066055"/>
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    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
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            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EJU02050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1592" mass="181068" checksum="E636C4F6D83A4631" modified="2013-05-29" version="1">MHDESILKVRITNVDYSQQVPGPLDRTESIFATLNKVPVLNVFGHTSAGQKACVHIHNVFPYLYIEYKGELDPGSVNKFINRLGRKLNHALTLVLRRNPYVQNTPQHIVAILPVKGVHFYGFHHRRSIFLKIMFSDPRLIRKVQLLLESGAICEKAWQTYESHVDYKLQFMCDFNLYGCNWLEVADCRFREPLPEPPEYDIPVSSIAPHMIPWNSANTPPELMHSVQPIPVRSTRSYNVLELDICAWDILNRHALTARPIASRLAPPFSGAGNPDELFVHSVRELWEDERRRRSAKGMDPTPPRPKDATRTIDPERTRWVASERFWAEVDARIDREKDKIGRVGPDDELKVIPWEAWLMTPFESVEALFPREHQRQRQRRREKQTEAVNAAEDDWSQRGDVENEAEDDAKWAGSQLLQRAVEEAQGVEDEWIQDPERQVEEEEEWESGYDPPPAQPRTPLKSQRTAPVRSRSGTPTKSGKVSPVNGDKGNGHAKRPNLFATPSRDHTPYRSSPLKNGVRTIEQEEREGSIPVLPQNSPDPWITSPEKEMTLKRGVHFDGEERPPKRARIEEADNAVVDPWIVSLDSFTSSEDAAPTCSPVATQRDPTKPLSSSAYTYGFMPPTRVDVMETLYPHKMYTDPHYSNRFDVPERAREYAGRMFKLAWGGRVSEFETTTQIFDMLSDEIVLPTITSAWEFASRAPTHREVENWLADPANMDKELTHAMKRRKQAQSQLDGMTPAKGYGIRATMHRPSEFSTREKQNMSVLAVEIFARSRGRLLPDPAEDEISMVAFAFQDDAGEGGRDTYEVGLILVANPQVDATRLRDLASANVDMVDAESELINKLIDRVLDWDPDVLTGWDVQSSSWSYLAGRAKQYGVDLSDQISRVMSPPSRNGQDRWSLTHTSTFRVSGRHVINVWRHLRKELTLTSYTFENVAFQVLKRRMPLYLASTLTQWFHSPVPLHTAQLIDYLLERTVTVIEILDETELITKTAEFARVFGVEFFSVLERGSQYMVESFMFRIAKPENFVLISPSKEQVGQQNAAECVPLIMEPQSACYKGPLVVLDFQSLYPSIMIAYNYCYSTCLGRVRNFKGKSKFGVTDLSIPPGVLELLKDDITISANGMMFVKDHVRRSLLSKMLSELLDTRVMVKQGMKTAKGDKSLLRLLNARQLSLKYIANVTYGYTSASYSGRMPAVEIADAIVQSGRETLEKAVHLINSTAKWGAKVVYGDTDSLFIYLPGRTKDEAFQIGHDMADTITSLNPAPVKMKFEKVYLPCVLMAKKRYVGFKYENPDDVQPEFDDKGIETVRRDGCALTRKMVEASLRILFNTQDLSEVKEYCRRQWSKILEGRLPIQDFIIAKEVRLGTYIEGAAPPPGAAVAAMKAVKDPQAEAQYGERVPYVIMRGEGRRLVDRAISPEVLLRNRDQRIDPIYYITRQLIPPLERIFNLVGADVQAWYDDMPKKLRANRADSVVVIPRRDKDVKTSKASASTIERHFRSNLCLVCEEQTDSAVCPSCLRDLPTTLYSLNTRMHLGEQRLRDTQQICASCTASPPGEPIRCESLDCEWLYERVKAEEEASAFAEIPKLIEQLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1H8</accession>
    <name>M5G1H8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1H8"/>
    <dbReference type="STRING" id="1858805.M5G1H8"/>
    <dbReference type="GeneID" id="63689014"/>
    <dbReference type="HOGENOM" id="CLU_051226_0_0_1"/>
    <dbReference type="OMA" id="IQMEVTD"/>
    <dbReference type="OrthoDB" id="5556956at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="316" mass="34408" checksum="0A462AD57FC150BA" modified="2013-05-29" version="1">MSSEGDAEDRGTMLAALEAHGQAFLRSFGPSAIPVHGVKRKRKESINSHTDNVDSSNPQQGDEDEWHGFGDDGPDHYQSMPSNDASKMDLPASGRPATDRPKTPVVVDFSHSRRPLSSAGQARSDKTFMSSKISKMKEDVSQRGDATAGQNEDDEQQLSDLRNDAELHRIIHTQLLSGSLDPMMDLKPSQKKKAMAGRVLEVAGKVKLGAGETDVRKEEHNKASKHIREGIRKKQKERAAQDLEEAKQLGNYHPTIKRLFAASSQPSAPNKRARGIGSGVGKFVGGTLKLSHAEIASVQGVPSKTKGRPGKNVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G203</accession>
    <name>M5G203_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_68835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626819.1">
        <property type="nucleotide sequence ID" value="XM_040775886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G203"/>
    <dbReference type="STRING" id="1858805.M5G203"/>
    <dbReference type="GeneID" id="63690948"/>
    <dbReference type="HOGENOM" id="CLU_041176_0_0_1"/>
    <dbReference type="OMA" id="SHAECEP"/>
    <dbReference type="OrthoDB" id="435520at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="623" mass="66758" checksum="220985F0756F43D3" modified="2013-05-29" version="1">MLSPQKEVPEEAELSHRSSLDSIAEEVRRTLQLAEDGSARDREAKPYVNKGKSASEPPASAIQSRVQITGEPSMPQTDSYSPSVDSNFPAGTSFLPIPAAPAKGASSENLAIAQQLRSPRYTKLLTLKRSPHRGLTVSLADVGSSTGHPVFVFLGLGCVRYIIGLYDEMAEALGLRLVCVDRWGLGKTDDVPAEKRGLLEWAAVMEEVADMMDITEFSMLAHSAGAPYSLATALRLGRRVAGSIHLLAPWVSTTVEGGYKWLKYVPNGLLKTAQAAEWKVQGWRLGKPPTIQYQAIGYNAATGASTGVDDRQSFQFSDYDDLADFDGRFSSRTSLQATINGISSLPPIPPTPPTSSDVSPKGVVKHKTSKGIMSIFRGNKHNGGISPKTPSSTTSTLPKGSRGSFITGRRHSNAGQSIMSATSTLPSLNLPTIEPDDVGLGIKFDILEEYAMTGALPTRKSDGPPTINPRAGLGRRSISLTSRNSSRNGGPSALAAPLMQRANTSPTAPPPKAPGKAITLADALVRASHAESLKGGTADLLAILERDSKPWGFSYTDVRHSVLVWYGEKDEKISINSVRWMERAMTDCKVKLVQGAGHSLLTNAQVVVEALESIAKECVIRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2D6</accession>
    <name>M5G2D6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626924.1">
        <property type="nucleotide sequence ID" value="XM_040768881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2D6"/>
    <dbReference type="GeneID" id="63683943"/>
    <dbReference type="HOGENOM" id="CLU_2372760_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="95" mass="10825" checksum="33BFF1FAD87EB92A" modified="2013-05-29" version="1">MGKVKGSTQSLKKKILQPESPIVFQPLKKNVLLGEGLIIRSLKQQGAFVIKEVWRNEREITDFFLKIIKAKVKKLKEEKLKEGPGPSLENPMIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2E2</accession>
    <name>M5G2E2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1-4-glucan lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631270.1">
        <property type="nucleotide sequence ID" value="XM_040772148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2E2"/>
    <dbReference type="STRING" id="1858805.M5G2E2"/>
    <dbReference type="GeneID" id="63687210"/>
    <dbReference type="HOGENOM" id="CLU_000631_7_2_1"/>
    <dbReference type="OMA" id="HSEPYWI"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06601">
        <property type="entry name" value="GH31_lyase_GLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF120">
        <property type="entry name" value="HETEROGLYCAN GLUCOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="344"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="4">
        <location>
            <begin position="783"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1056" mass="119760" checksum="356684FBA7913798" modified="2013-05-29" version="1">MSPSSLVAGVSDPLNFVPAEHFFTRAAQYPHGPSSITNVHTSSSLKSEDPLRFAAGLEFDDGTVAIIHFASPSVWRVRYDPTFKTIADYSMDNSRSVMEKTWGALVDSIQRDLNTMWRTRFTPSEDGEYFTLATVTYLSVEDRDDDKNGTIDTKLYMWKSPFRLQVTRKLEVTPLIIPVPPDLHETNVPMEKVVWQTIARPFRYEPMKYRVNNIILHVWKKGSAEFLGFGEQGGKHLLKTPSQMNYYCYDNMLYGNLYNKGPLDDREPLYHSCPYFVEMNALPGYSNVTATFVDNYSQVVIDLGKSNAGRVSIGTRFNGFDAYIMSADNVAKLIESHTLLVGRPHLKPRYVLGNHQGCYGYRTREDLETVVAEYRAARIPLDGLHIDVDFQDRYRTFTWNEDKFPDVPGMFAELREKGVKCCTNITPVISLKDEGEGDDYPTLQEGLAKNYFIPDTRYLEGTSGKPEDVRYTYYWGNLDEQGLPVPQEVDPNLGSSTPVYEQNYSTFADNFNSGSPYHGGVSYGAELGTPGYYLDLNRPEVRDFWGQQYEKLFEAGLEFVWQDMTTPAIATGYGDMKGFPSRLWISTDPHFTEPGQPPPRKTAAELWALYSFNLHKATYLGLNKLECRENKRNFIVGRGSFSGMHRYAGLWTGDNASTWDFWHISVAQVLALGYIGVTIAGSDMGGFMPNGDEKFCDPDLLIRWYSGSVLLPWHRNHYIRRSGEKWFQEPYQYTNYLRDHPEIEADQGWLYSAVEPICRYYVSLRYSLMQLLYDKMFENQVNGLPIVRSMLITDPLDQTLFNEQDHFLDSQYVCGQDLLVCAVTESHTINIGKRHTYVPQPDNWYTFNLRIDGSLGLPLSPVVEGGSVFMYDCHISANPDHIPYVTPMYVREGGIIPQIEVRQYIGDKSPPNPITLHIYPGKNNTYSMYLDDGASRTSAPDMVPQEEFPEDNMARSEYREVLVSQTTLGTSRHITLTNVHDGYGPANVARDIGNTYTVVAWVDPCEPQLRTGTFTDRSGKEVTAGCSFKWDAAVKAGVATIPVELLGGMLTIVMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D4</accession>
    <name>M5G3D4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625170.1">
        <property type="nucleotide sequence ID" value="XM_040773817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D4"/>
    <dbReference type="GeneID" id="63688879"/>
    <dbReference type="HOGENOM" id="CLU_1081915_0_0_1"/>
    <dbReference type="OrthoDB" id="3229989at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="27426" checksum="5393E525FC8BC527" modified="2013-05-29" version="1">MISSQQQPLPTPPDTPPQFPSTVLDCPALPSPPSEPVPVPTTAPTKRTPSFHLILPLPRPASMPLLSPSPSASLLASFYPPSSAEAQAHDHIYEHILHDPLIGATEMGQSAAYAAVRRYILAEDLFIFPTDGRQLSDVLGRFARDVIHSLISQAKTRIEEGGYARARAIAMHSLHTQVLTPSGTSTLLEIHKELTPALSRSEGSVSGDSEGEEVRTPGLASSMGRRARMRMTMTRMQEKDGTAPGKAGGGEVVIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3J6</accession>
    <name>M5G3J6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_88490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629689.1">
        <property type="nucleotide sequence ID" value="XM_040776858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3J6"/>
    <dbReference type="GeneID" id="63691920"/>
    <dbReference type="HOGENOM" id="CLU_1970499_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="14254" checksum="610843E764E5DFE3" modified="2013-05-29" version="1">MSGEPRGWTSEITQSSARSTLVPSYRPCSPSTWSFKHTKDQPAPNLYITPSFPSPNPCEPPSHSPPPNLCHSPIPIPGKLRSPPSLRPGVPRIPHRPFGKKHRHILVHEIGTNDSCGFRCRIYHHYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3L3</accession>
    <name>M5G3L3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_78174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630158.1">
        <property type="nucleotide sequence ID" value="XM_040776320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3L3"/>
    <dbReference type="STRING" id="1858805.M5G3L3"/>
    <dbReference type="GeneID" id="63691382"/>
    <dbReference type="HOGENOM" id="CLU_004196_0_0_1"/>
    <dbReference type="OMA" id="WVAKTSW"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="902"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="969"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="904"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="976"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1048" mass="117267" checksum="2277362F895EE886" modified="2013-05-29" version="1">MDVSGLVNLFTATYSVDQNVRMTAEIEIHKVASHESFIPAVMQIISATDVSLATRQAAAVYLKNSFTSGLGEDSANTQKTIAVLKSSILPLIGSSPSHSITSILRTTLGYLVKATWPEEWPELETDVRKLLASGRGREIFVGLISLLEMLKAFRYSSSPHVANVTANIFPLLHPLATKALTAHPSTDKAEILHLVVKCYWMSIQQDLAVCLQAPEGIMPWGTLFLQIVSHQVPLSVQGASPDDLDDLAGTPYWKAKKWAFRVLNRLFRKYGNPSQLPAIYKKEYTPFATKFIGLFAPEILRRYLAQLELYVSAQQRNNWEQGWMTDRCLCLILDFLTESIKPKSTWELLKPHVPDLIRHFVYPILRFTTRRAELWEADPVTFVQESLGNFEDLGWPDPHACGFLLGLARSRSKSSYQIILTHISDILGQYPGSQGPESKYGVLTMIMALDDIFVNHPLSKGHVNDILTQHIIPELTSPHAYMRSIACDVITKFEENGVSWVDGQLLNTFQIVMGAMRDAELPVRVNASFAFSSLMEQPEVRPLIAPHIGEIIQAFLKLSDELGLDTLSAALDNVVAYFADELKQLALPIIVHLCGSYNTLFSQIEDARALGEENNDDEITDKTMAAIGVLRTIGVIIDSQKDSPDLLKAIQMTVLPIILRTLEQGNVDMFDEIYTLTDSLLTQLNNISSYMWQVFEATYKAFKILAVDYFEDMMPVISFFIEHGVQAFSERPDYCAMIVDMFRTIAFEDSAGAWDRRAVSMIAETFIMQSPGLLNQSVAQLVEATIRILILDGEDSPQRTQKVNVLLSLLAVYPTETLIALEATEKTSWAFEQWLHEVPKLARVHDLQLIIVMVSRLMDLPSEQVPPPAASLWPIILSNALRCFTALPAAEQKREEIARKLLEEDVDEMEDEDEDDHDDASMEEDEEHAYDHAEDEDGDVIDEETEYINQLAEEAARLRAKSAAILAGQPIPASELPDEDDDDEEEEEDWFFETAVDKVDPYIKFAASLHAFQTSNPQAYVAATSGVGQEGQVALMEIGKKALERSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3P3</accession>
    <name>M5G3P3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630188.1">
        <property type="nucleotide sequence ID" value="XM_040772427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3P3"/>
    <dbReference type="GeneID" id="63687489"/>
    <dbReference type="HOGENOM" id="CLU_2775883_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="69" mass="7685" checksum="8C7E018E2C03AEA2" modified="2013-05-29" version="1">MALFSERIVQESQSTKKHVEAMMQEALTASAITKLPDLTTCGKYSSTYFENITLMGGYDLLGIFSSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3X4</accession>
    <name>M5G3X4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoside hydrolase family 79 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627444.1">
        <property type="nucleotide sequence ID" value="XM_040768690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3X4"/>
    <dbReference type="STRING" id="1858805.M5G3X4"/>
    <dbReference type="GeneID" id="63683752"/>
    <dbReference type="HOGENOM" id="CLU_023945_0_0_1"/>
    <dbReference type="OMA" id="MQMAYSN"/>
    <dbReference type="OrthoDB" id="2796951at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067574" description="Glycoside hydrolase family 79 protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="63803" checksum="400F972FB9BA7E07" modified="2013-05-29" version="1">MLCLALFLLPLLRSARADVTIYTTFPNFASSAPAPSPTGPYSGLPAFDPTTIPPPAPPNPPQPTDVPITLFQGGMQGLSIPQMGNLLGFSIELSVSNTIIGKNSKLLNVPFLNYLNNIRLRAGAGPIVRVGGNSQETETLFVDGLPDGSELDKINQGIGANGVINTPIINFSPELLYSLANISALVEAQWYFGLSFNDTSADGNALVVAQYAQDILGNNLIALQLGNEPDLYSNNGKRDPNYGIPDYMTDFAKVEGDLMAASGVQRKETLIGPSICCEWQIDDVLSAGYLTQFSQGLRQVSVQHYPANNCKLLGVIQPSDIFPSYLNHTAAQTFVQPYLDAVPVVLGAGKPFVMLETNTASCGGFLGVSDSFGATLWTLDLAFQLAWANFSTVLLHTSGTSVYYNPITPPPGNETRTKQWNTGSTYYAMLAVAEMFGSSNISQIIDLGTSETSIYAPSEKWNITWAGQTLSPGGAQSSDGVLHGSQNTVQIACDTANNVCYIPVPAPSFALVFLSQQALTDSTSQSDGIAGSGGGAPGPLSFTPTSTRGGGATGVDPGVLATSNGGVLGGGGLGSTSKEGDARLNVPFPVYLVVSTSVLGIVGMMLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4G3</accession>
    <name>M5G4G3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_24242</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625530.1">
        <property type="nucleotide sequence ID" value="XM_040773606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4G3"/>
    <dbReference type="STRING" id="1858805.M5G4G3"/>
    <dbReference type="GeneID" id="63688668"/>
    <dbReference type="HOGENOM" id="CLU_047181_1_0_1"/>
    <dbReference type="OMA" id="ASCAEYI"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF73">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="29"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="170"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="34"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT98632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="342" mass="35969" checksum="41B82F45F0BAD3A4" modified="2013-05-29" version="1">MMFSSLSRFAPVAARGARGFASSSARHHKVAVLGAGGGIGQPLSLLLKLDPLVTQLSLYDIRGAPGVGADISHIDTASNVKGYPADQLEVALDGAEVVIIPAGVPRKPGMTRDDLFNTNASIVRDLSKACAKVCPDAHMLIISNPVNSTVPIVASTYGSKFNPNRLFGVTTLDVVRSSRFLGEITGEKPEDIRVTVIGGHSGVTIVPLLSQTPQAQKLQFGGAEWSNLVHRIQFGGDEVVKAKDGAGSATLSMAYAGAKFSNQLLRALNGEKGIIAPSFVRSPLFESEGVEFFSSNIELGTGGVEKIHQVGALAPEEQKLVDACIPELIKNIKKGQEFVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4H9</accession>
    <name>M5G4H9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632055.1">
        <property type="nucleotide sequence ID" value="XM_040771644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4H9"/>
    <dbReference type="STRING" id="1858805.M5G4H9"/>
    <dbReference type="GeneID" id="63686706"/>
    <dbReference type="HOGENOM" id="CLU_046006_4_3_1"/>
    <dbReference type="OMA" id="FGTHKIN"/>
    <dbReference type="OrthoDB" id="5371818at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07253">
        <property type="entry name" value="GLOD5"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
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        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050383">
        <property type="entry name" value="GlyoxalaseI/FosfomycinResist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
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        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 5"/>
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        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="VOC"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="25"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="16780" checksum="17B10D7D69C88A17" modified="2013-05-29" version="1">MSTTSSNANPNPSAVPRPCPFQIDRVDHIVLQCQDVQATILWYTKYLGMKHERFHTAGGERHALRFGQQKLNLHPSSAPYQPHAALPLPGTQDLCFVLSPPATADRVLEYWREEGLEILEGGVVGRTGAVGGLRSVYTRDPDGNLIEVSNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4P0</accession>
    <name>M5G4P0_DACPD</name>
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        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
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    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_86365</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
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    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776772.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G4P0"/>
    <dbReference type="GeneID" id="63691834"/>
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    <dbReference type="OMA" id="HHDWVST"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016705">
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    </dbReference>
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        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FLAVODOXIN_LIKE"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0349">Heme</keyword>
    <keyword evidence="10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="12">
        <location>
            <begin position="302"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="486"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="734" mass="81137" checksum="1BEEDA8C0107D16A" modified="2013-05-29" version="1">MPKFMHPLRVINKQYEADIKLMFEVVDEVIAHRKTHPLTGSRDLLSLMLEGKDFMTGRGLSDTNIRYQLLTFLAAGHETTSGLLSFALYHLLSNPQAYAALQKEVDTVLSDNPLTVDHLSKLPYTNAVLRETLRLNSPALGMVVTSFNHTELLCGEYEVRKGWPLLLDFYGLHRDPAVWGDDAESFRPERMLDDKINTLPPNSWKPFGNGARGCIGRALALQESVMMLATLFQRFEIRFDDPSYRLQLKETITTKPTGFKIHAIPRAGKKVFGAANGYMSPGVLGETLQKVGHTAPGKGAPLLVLFGTDSGTCERFAEQIASDAVIHGFNPKIGAMDSVEDVANLPRDAPVIILTSSREGQPPENAVRFVQALKEMTATTKPLQGVKYAVFGAGNHDWVRSFYRIPKLVDSRMEELGAERLIPRGEGDAGGANVYNSFDAWEKALWSAVSKDLNDAAPEAASELDIEDDLIVAVVGATRDILLRQPDLTEGKCVENRVLTASDQPVKRHIEFQLPLGMEYQTGDYLAVLPLNSPESVHRVLAHFNVLGETKIVITSRAPTTLPTNEPVSLQDLFSGYVELAQPMSQRNLDEVMRYAPVDGPERQALDKLVANPKTDVFDKHLSVLDLLEQHPSVKIPLAQFIKLLPSMRIRRYSISSSSLWKKANCTLTFSVIRGSSTAGKRDFLGVASNYLANLMPGERNLPGCPRASRKTSLMPFSSGVVHNALHSLRTECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G553</accession>
    <name>M5G553_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal L1 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_115536</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the universal ribosomal protein uL1 family. Highly divergent.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630254.1">
        <property type="nucleotide sequence ID" value="XM_040770025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G553"/>
    <dbReference type="STRING" id="1858805.M5G553"/>
    <dbReference type="GeneID" id="63685087"/>
    <dbReference type="HOGENOM" id="CLU_026457_4_3_1"/>
    <dbReference type="OMA" id="WSDEDAN"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000004">
        <property type="entry name" value="Ribosomal L1 domain-containing 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="268"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="482" mass="53169" checksum="A92543F7CFFDF469" modified="2013-05-29" version="1">MVAETLIDDHVSQDQALLAAKALAAYVHKQQEKEEDELLPQKQDVVWLVVATKRIPRTHKVKPIKIPLIHPVIDPRETSICLLTKDPQREYKDLIAEHKINFISRVVGVAKLKGKHKPFEARRQLLKEHGLFLADQRIVPLLPALLGKMFFDAKKQPVPVDLTAKDLKKELARAVSSTYMHQNAGTCVSIKLGTVSHTPEQIVANLTSALPAIVKHIEGEWENVLSLSLKTGRSTALPVWSCSVEERFSVPSLDAARQEVLEKKALEKEKKEKGKKRKAEETAAEEGGTKKPKKAAKKAEVVEDEEEDDEEFTGFGNDEDDDDDAAEAEEAETEPPAPPKPKKTDTKKPRKTVQEEADLEPLSLVSSGKPKSAKKPQASAHVAEVPKPEKSKKSKKSEPAMPAAAESKPEKIKKSKKPDQETESEPVLPAALSNPKPVEKVDKKSKKGGSVQRLQTKLQRAGKGSAAEGAKRKVLGKKRIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G557</accession>
    <name>M5G557_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ebp2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_78276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630259.1">
        <property type="nucleotide sequence ID" value="XM_040776329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G557"/>
    <dbReference type="STRING" id="1858805.M5G557"/>
    <dbReference type="GeneID" id="63691391"/>
    <dbReference type="HOGENOM" id="CLU_036007_0_1_1"/>
    <dbReference type="OMA" id="DAHKGRD"/>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="437"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="53821" checksum="2EC127757AB9BC06" modified="2013-05-29" version="1">MPRPQEDRKQNQKPAKVAKAGKEGKGKAGKDGLRARGGKGKIVKGSTFLLASSPVEPDEDYEDEEFVPTALEETEEGAVDNAPAEEEHDQDNDEEEEEEEEEEEMEDEDDLKGMERLVKALGDDGLDEIAKRELGALADGEEDEDELDGEEEDEDDEAPELVDVEQDQDDGEVDEDANDMEEDDDDDDDDEEEEEEEIALDDVDGEVDEDAVPKQKVTIDNQPAMRRLRETIELKDMDWTETLAVTYPHKMEDEVKDPDDDLDRELQFYKQALWGVEHSRDLAVKFSLPFTRPNDYYAEMVKSDAHMERVRSKLVDERAGIKKSEEKKRQRDLKKFGKQVQVEKLKEREREKKDVGERLKSLKRKRKGALDGDGGMADEEFDIALEDALADHPAKRGRGRGKPGISREQRDNKFRLGAGGGRRSKQNTRESTDDFGAGRGRGRGGMRGGRGGRGGGRGGRGRGGSQRPGKSRRAAMRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G561</accession>
    <name>M5G561_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU05396.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G561"/>
    <dbReference type="STRING" id="1858805.M5G561"/>
    <dbReference type="GeneID" id="63684708"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_3_1"/>
    <dbReference type="OMA" id="MTNANES"/>
    <dbReference type="OrthoDB" id="3346544at2759"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
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        </location>
    </feature>
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        </location>
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            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
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        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="324" mass="36155" checksum="3FD0DE4B94A48D55" modified="2013-05-29" version="1">MANSLDISMATLASFLALGILNGIFFVLFIGSLYVLFRRGDTQRANWILASAAIIMFVLTTTHLGFSFSRIQDIFIWSPANALNLNEWKELCRTTLTCVYMGIADTLLIWRCWIVWNRRLRVVALPIALLLTCIAMIALLLRAMYSSTQSAEGIFALSLAPWIIAVLVLTLVQNLLVTCLIVLRLWRMDSVVNKRTGSKPFQPVIAIVLESGILYSVTLFIWLLTYSTHSNSAYIMVDCINPMIGITYCLLVIRVRTVDPGISADETIPDEFKIPDLSQLASLEVHPSLQRNTAARSAGTTRTSAQNLEIPERDAHQEDPDMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
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    <name>M5G586_DACPD</name>
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        <recommendedName>
            <fullName evidence="3">Glutathione S-transferase C-terminal domain-containing protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_106553</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EJU03395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35924" checksum="A76FC2C541163456" modified="2013-05-29" version="1">MHRVWTILEVVQHIADYVAENGDLHSMMLTLRMCFDTAAPLIWRSLDVQKVDELLKILYVNWEHNGTSIVPSSFGRVTLYASFARAIHIDDRFTVYCEDQSKIDIDFPRYLSIAIDLFSSNTEHWFPNLQSLSLDCDQKKLQAYIAILTKCNRFCEESSAGRAGAQLTDVSELLNSGGGRDERPKKNRPVRIYTKAKRDEDSSLADTNASKMRPSGVAPFFIRLIARLICNNVQHLLIDPQLKENAEMIEAHLAKSSTGWFASAPNPTSADFLMIFTLETLVSRGPGVGPKIKEYVARVHEREAWKRGIEKGGKYTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5M1</accession>
    <name>M5G5M1_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="51" mass="5587" checksum="7B919488D3BE6BAF" modified="2013-05-29" version="1">MLSLTSLDTNTRPRKAQQEQQHIFLPRLAPGGPNRRGKSPGSTGQAEEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5P5</accession>
    <name>M5G5P5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_96336</name>
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    <organism evidence="8 9">
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        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625980.1">
        <property type="nucleotide sequence ID" value="XM_040777360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5P5"/>
    <dbReference type="STRING" id="1858805.M5G5P5"/>
    <dbReference type="GeneID" id="63692422"/>
    <dbReference type="HOGENOM" id="CLU_014689_3_1_1"/>
    <dbReference type="OMA" id="GGCKWQH"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000201">
        <property type="entry name" value="TRM2p tRNA methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025795">
        <property type="entry name" value="tRNA_(uracil-5-)_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="RNA M5U METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061:SF30">
        <property type="entry name" value="TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51622">
        <property type="entry name" value="SAM_MT_RNA_M5U_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="7">
        <location>
            <begin position="110"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="640" mass="69638" checksum="A91DA81744FC33D5" modified="2013-05-29" version="1">MHLVRVGHLSLRFTCHPSLYIRMSKRALSGSPVPSASAPSSPKRPKFSVPPPAVPAAVGVPTAHKTKKRKRPPPPEFGSREDVLQKEVKRLLESEGRVLGSDEGWDAPEGAGMGVELEVRVRELSSTGDGLALVPEGFPPWVVVTPFALPNEKILVKLLRPAHGHSEAKLLEVLEPNPELRDMSLVKCKYFGKCAGCQYQMLAYDTQLDVKRDVVVRAYKYFSKLPESSVPTVLPTIASPLQYGYRTKITPHFDAPPWQRQGRRGKDRPPRAPRENSDWEVRIGFDEKGEGRRVLDIEECPIATGVINEGLKEERKKIQETIENYTRGATMLIRDSILYEPANPFKDAATEVRDDYTVDSSAVGPSAIVGRIGRTVGAPAVENEGTVSNADAGGKASIADGVDAAPPSSKPDGPATCTDDGKERHICVTSTAATIYDRVGPYLFSFPASAFFQNNSSVLVPLTDHVKTAIESATVGQGQAHPTHLVDAYCGSGLFSLMLSSSFEKISGIDISVHSISSAVRNLALNDLPSDKFAFQTGTASDIFASVSHFPSSQTAAVIDPPRKGCDEPFLRQLLNFRPKVIVYVSCNVHTQARDLGWLLRTQEEEGRTPENGAYGIVSLRGFDLFPQTGHVESVAVLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6X4</accession>
    <name>M5G6X4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Transcriptional adapter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_76928</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631353.1">
        <property type="nucleotide sequence ID" value="XM_040776234.1"/>
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    <dbReference type="GeneID" id="63691296"/>
    <dbReference type="HOGENOM" id="CLU_018273_3_0_1"/>
    <dbReference type="OMA" id="YNGNHRP"/>
    <dbReference type="OrthoDB" id="270417at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.90:FF:000008">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="11">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="12">
        <location>
            <begin position="424"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="213"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="514"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="619"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="70304" checksum="F77D8734FE58573F" modified="2013-05-29" version="1">MTVSQSRKSQQSSKEGRDRYSCDACDADITNFIRIKCATPVCKEIDLCPKCFCEGREVGSHKAWHDYMVIDQPTYPIYDEAWGADEELMLLDGILSSGLGDWQGVSDKLFGLRSKADIEYHYRSVYLSSPTWPRVEKRPFPDYDREEFLACKRRRIKQMSDALPPPPPPKAPTSGPANHEITGYMPGRLEFEHELVHEAEEAIADMHFGVVLQHGGDEQPEPEPEPEPEPEPEPEPETDGDGDGEDEDGPGEETEPPEPPIGIEEPEELEVKLSLIKGYYDKLDKRIRAKQVVFQRGLLEYKKLQMAERKRPKEEREMFQRQKPFARVQTAEDFEVFVDGLMYETALKKRITELQQMRRDGVLSTAEVERYEKDKAQHANHRAYVDRAYPQSKSVRGSVAPGERDSVPPFGRGSPTTLSVIPGARVRKPPPPLNLANAHSIHLLTPAEQVFCSTMRILPKPFLGMKEALVREFARRNGRMTRREAREVLKIDVNKVGRIWDFLKDCGLLHLSHEEAPPPSSSATGPVKSATKSPSKPVSTVGKVAASLTPPPASVGLPRPSSAMGNKPFAPSPLKNASHPNPPTPALNGSSPKGMSTGVSRPPPLIGKKPPNSGPALSRTPSFQSTKNSGGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G791</accession>
    <name>M5G791_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_17288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626530.1">
        <property type="nucleotide sequence ID" value="XM_040771272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G791"/>
    <dbReference type="STRING" id="1858805.M5G791"/>
    <dbReference type="GeneID" id="63686334"/>
    <dbReference type="HOGENOM" id="CLU_019618_2_1_1"/>
    <dbReference type="OMA" id="KLITHQY"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000475">
        <property type="entry name" value="NEDD8-activating enzyme E1 regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="31"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="560" mass="61615" checksum="D8DE66E16062FC79" modified="2013-05-29" version="1">MAQTAEAKTIEEATVTIVSPQGRPDEKTRRYDRQLRLWASSGQAALESARILVISGGATSTSTLKNLVLPGIGEFTILDHLPVTYADAGNNFFLHVNGIGKSRAEEAVSHLAELNDSVKGKADTRDVNAVLENEPEFFLSFTLIIAVNLSPEIEDRLAQALRSGASTPRDTVPLMIVRTAGFYAMIGTQIGEHTVVDAHSETPPSLRLDNAFPALLEYARAIDLDSLDSTDFGHVPWVVLLVKALENWKQKHDGQLPKSYAEKQELKKSLEKMRRRGDEENFDEAVAQAYRMWTPTVVPSETRALLSDPSVTTITSSSPSIFYFLLALSHFVQQHSYLPLVPTLPDMHTTTDTYVELQNLFRAQADREMLVFEDCLKRAVEEVHETWEERESLGLGRAEVKEFIRNAAGVRVFKGKKWGSVEPSEIEASDQKPVTALQNELESGMLPAPAAVYLAFLCSADFYSAHARQPQPTEADNQLLTTYATQRLANGGWNGELPETVTTALGEIARAQGSDIPTTAALTGGLVAQEAIKFLTRQYVPIEGTCIVDLIRSTTGTLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7F3</accession>
    <name>M5G7F3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">sphingolipid 4-desaturase</fullName>
            <ecNumber evidence="3">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_19435</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633045.1">
        <property type="nucleotide sequence ID" value="XM_040771509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7F3"/>
    <dbReference type="STRING" id="1858805.M5G7F3"/>
    <dbReference type="GeneID" id="63686571"/>
    <dbReference type="HOGENOM" id="CLU_032156_0_0_1"/>
    <dbReference type="OMA" id="GATCNQN"/>
    <dbReference type="OrthoDB" id="200948at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="11">
        <location>
            <begin position="65"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="381"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="45485" checksum="EB7664D4D763BDD3" modified="2013-05-29" version="1">MAVAEISSSLKPRIDFSLYGGAESAGPLAPKSKSSGGPKINAPSARRTVVEAGEFPEGMIARKEEDPSDFLWLLTEEPHRSRRKQILKDHPEVTKLMGHEPLTKWIVLGVVVLQLAAAYLLRHTHPFSPVFLLTAYAIGGTANHNLFLAIHEITHNLAFKGIKANKLLAIFANLPIGIPYSVMFKRYHIEHHKYLGEDGIDTDLPSRLEMLCMNNVAGKAFFCTFQILFYALRPGFIRAQTLTPWHFLNFAVQLAFDFLLYLAAGPKAIIYLIMSSFFAGSLHPCAGHFIAEHYVWDGLNQETYSYYGPLNVLAYNVGYHNEHHDFPSVAWTRLPALKALAPEYYDTLPSHPSWPMVTFNFIFDKNVGMWSRVKRLPTGARTPDVGGLPPKGGQTPIVGTPMEEKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7W9</accession>
    <name>M5G7W9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_105294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631124.1">
        <property type="nucleotide sequence ID" value="XM_040768069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7W9"/>
    <dbReference type="STRING" id="1858805.M5G7W9"/>
    <dbReference type="GeneID" id="63683131"/>
    <dbReference type="HOGENOM" id="CLU_001265_52_4_1"/>
    <dbReference type="OMA" id="LLWFIWM"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="60"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="52941" checksum="D8C34F8B0077D323" modified="2013-05-29" version="1">MASSINAPSVGNEKGPSVPDMDTDSNILPEDATDPVYLVKAKVINDALQEIGMGKYQWHLFGVAGFGWMMDNMWPIITSLIFTPVVNELHPSRGPFLQLAQNVGLLVGAFCFGLGSDIFGRRWAFNSTLFITGVFGLVAGSAPNFPAIAVFAALWSVGVGGNLPVDSAVFLEFIPGRNQYLLTILSVYWAFGQLLATLIAWALLTNFSCPEAVGSCPRSENMGWRYFMFTMRGITLVCFVLRFVVFHLHETPKFLMSRGRDDQAVHVIEKVALYNGSTTSLRSEQLRSLSEKPEGPAQDTSATGAVRRRFEKFNAPHVRELFKTSQMAWSTGVIVLIWALIGLAFPLYNAFLPYLLATRGAQTGTNSTLLKLPKFGRRGALALSTVLTGVFLFASTTAKTQDALLGWNCAYNFTSNVMYAVLYAYTPEVFPAKNRGTGTGIAATANRIFGVMSPIVAMFANLNTPVPVYVSGALFIFAGLLVVLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G853</accession>
    <name>M5G853_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631214.1">
        <property type="nucleotide sequence ID" value="XM_040772124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G853"/>
    <dbReference type="STRING" id="1858805.M5G853"/>
    <dbReference type="GeneID" id="63687186"/>
    <dbReference type="HOGENOM" id="CLU_010480_3_0_1"/>
    <dbReference type="OMA" id="PQMSESF"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="420"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="748"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="798"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="831" mass="92002" checksum="B07116773EA9E6A6" modified="2013-05-29" version="1">MSSGRSPHQINDSFQLSAYPSSRSDADDTTTLHSDIPVNSSRVNLVGRDMTYNGAPASEDDHNVSTPKAKNFRQSGEKRPHSSRNPSWDMLGGVGHQFNEGFEFKTSTAKEEHLRFAEGDFAVTPMSRFYAYLLNLSIFTRWTLYILPVLGLLWIPGILGLTVAKDARMATVPLLYWSIWFSVVWAGWWAAFATAMIFPRVLRATVGVVLLGARKYIDFLQVCERYVAFLGWSIAIWISFTHMLELFAQPTNPLNSALTTIAGICEALFISSVILLVEKLIIQYIALAFHETSYADRLAVQKMNVKILVILYRNSSNIPGRLDTMNDDQSMMSRMNPKKVLKDFLHGVRSVAETSATALGNIATEIAGASVLQPNSPEGRVQTALSSANKSRLLARRLYYSFRNEGAKSVTLNDIARFFPDFETAQLAFTLFDKDGNGDATRDEMEMACMETHRERLSLAASMKNLDSAVGRLDAILVYIWFLVAILVLIACLDTTLYTSLSAFGGSLLALSWLFGGTATEILSSIIFLFIKHPYDCGDRVDIDGYQFTVKEIQLLSTIFMTTAGKTVQCSHAVLNTKYVENVRRSGQMSESFTFDVDFSTTFEQLEKLRAKMLAFVTAERRDYLPAFDVIVQDIPAQGKMSLSVMIKYKSNWQQVALHAQRHNKWVCALKEAMHDCKIFGPAGAGNPSPPAAPPSQYTLVPWEEAKPAPPEPAPAYREPLMPRGDWNLSDRNAVLRDDERDVFGVSDELTGGTMRSGGITSPSSTRPNTRSNTPEVGMSYVRGGQVPPVPSLPSHVAAGAGRRMASGSSGEEFEMRGAPRMTRARSGSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Z0</accession>
    <name>M5G8Z0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_79132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629231.1">
        <property type="nucleotide sequence ID" value="XM_040776378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Z0"/>
    <dbReference type="STRING" id="1858805.M5G8Z0"/>
    <dbReference type="GeneID" id="63691440"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OMA" id="LFGVQCD"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000398">
        <property type="entry name" value="Probable 2-deoxy-D-gluconate 3-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF5">
        <property type="entry name" value="2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="28123" checksum="F0AC763BEE58ACC8" modified="2013-05-29" version="1">MSCEPTPSVHVSQLFSLKGKVALISGGTRGIGEACAIALGEAGASVCLIQRNTSNTSTRDALRLLGVKAEIVPCDLANLDEVRTVFDRALEMMGGEIHVLVNCGGIQRRHPAVDFPEKEWDEVIDVNLKSVWLLCQAAGKHMVPLRRGKIINFASLLTFQGGLTVPAYAAAKGAVGQLTKALSNEWSKENVQVNAIAPGYIATDMNERLLADPTRLRQISERIPAGRWGAPADFAGPTVFLASEASQYVSGEVLVVDGGWMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9S7</accession>
    <name>M5G9S7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">DACRYDRAFT_93405</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631939.1">
        <property type="nucleotide sequence ID" value="XM_040777154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9S7"/>
    <dbReference type="STRING" id="1858805.M5G9S7"/>
    <dbReference type="GeneID" id="63692216"/>
    <dbReference type="HOGENOM" id="CLU_011476_2_1_1"/>
    <dbReference type="OMA" id="IHAWFAN"/>
    <dbReference type="OrthoDB" id="68336at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EJU05045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="471" mass="49669" checksum="F0CAA3D94F886A8F" modified="2013-05-29" version="1">MRGAYPSGSDRSPFADPSGDLVPQFDSQMHSPLGRGAESGAMYGERFGGAGGNGGAGGGYRNYDTGNSEWLEKQQASSKRNKMLIIVGILVVVIAVVAGIVAGVVISKHNSSSSSSGTSSGGSSSGGSNTESSGGGTAGQGVLRGSAGVVQLTDPNDASTYIKDPRLKNSFYGFAYTPMNVQLPWCGAVQANVTEDVILLSQLTTRIRLYGADCNQSALVLEGIQQSKVNLSVYLAIYVTDNTTSYEEQKQKVLDAITTYGVDHVEGVAVGNEFILNNLTDLNLSDPNSTAGISAADYLISLMADTRQSIQALGLSKTIPVGTADAGSMITPHLLTGADFGMANVHPWFGNVAIDQAAGWTYDFFEDFDVAPSLATTNKPPVSIAETGWPTASSSVADETDGPSTASVANLQTFMNDFVCPSNQNGTQYFFFEYFDEPWKDAEFGGVEGWWGVFTSNKQLKNLTIPDCTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA07</accession>
    <name>M5GA07_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_99760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629636.1">
        <property type="nucleotide sequence ID" value="XM_040777621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA07"/>
    <dbReference type="STRING" id="1858805.M5GA07"/>
    <dbReference type="GeneID" id="63692683"/>
    <dbReference type="HOGENOM" id="CLU_046574_1_0_1"/>
    <dbReference type="OMA" id="VFPMTWK"/>
    <dbReference type="OrthoDB" id="93019at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="24"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="400" mass="44282" checksum="FEA8CC9CF2489939" modified="2013-05-29" version="1">MAAAAITTHPLPLPPSADPSYFHTFGTEVRGLDPGNLTPSQFKLVEDLLYKHSALLFRNADLSPEQQYTLTKAFDPSSESYGHGNNKTGGEKKSILHPDLKTIPRQPQVQLIGNGLVPEHEGLVNAQLKHPHHRTFHKTVVPPEDDLKYTRFYRWHIDAALYDLSPPKVTTLYALAVPQGEAQVCRYDDGTGDELPVPLGTTAFVSGKTMFDLLPPEMKSVAVRTTVKYAPHPYVWMAPAHALSTGLGLETEGLELPLNELPQWEEGKVKFLPMLWKNPVTGNLHFEVHPCGIQELLIAPLPKGASRDNDGASYPSGAHLTELKDVRDLVYKMQRPAIAPALVYPHDWNEKDLVIFHNRGVLHSVVGAFAEGQVRMFHQCNLAASDDPAGPSEEDIRKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA3</accession>
    <name>M5GAA3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_75103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632638.1">
        <property type="nucleotide sequence ID" value="XM_040776109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA3"/>
    <dbReference type="GeneID" id="63691171"/>
    <dbReference type="HOGENOM" id="CLU_053011_0_0_1"/>
    <dbReference type="OMA" id="KSTWPTD"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39454" checksum="AE5C1D5DA95019CE" modified="2013-05-29" version="1">MAPQEFKVLTPEMREFFMDNGYLIIPQALLPEYADEFTKDVWTRLGYNPDDKTTWAKDRIHMAWHHAEEARKMAPKAWAAICELLGGEDRVTETSAKWRDNIILNLGAAEWKEKFLQPKELDNWHIDGDFFRHYLDSPEQGMLVIPLFSDVLHNGGATYISPDGMELAARWLAEHPEGTMPASSGGFKFADLIPECKQFVEVTGKKGDVVLLHPLMLHSATKNHIQQPRFITNPPVAVKEPFNFNRENPEDYSLVELKTLRALGKDRFPFKITGTRDHVTAPRVPFQQAILEEELERLVAYAKEHDTKPNTVHLGPEGEYERTHLVPCGNQFLSTPSNLARLVSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAG2</accession>
    <name>M5GAG2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-binding protein VTS1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">RNA-binding protein vts1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_21330</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA-binding protein involved in post-transcriptional regulation through transcript degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629831.1">
        <property type="nucleotide sequence ID" value="XM_040772342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAG2"/>
    <dbReference type="STRING" id="1858805.M5GAG2"/>
    <dbReference type="GeneID" id="63687404"/>
    <dbReference type="HOGENOM" id="CLU_017632_1_0_1"/>
    <dbReference type="OMA" id="MSTVNNR"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09556">
        <property type="entry name" value="SAM_VTS1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000033">
        <property type="entry name" value="Protein vts1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037635">
        <property type="entry name" value="VTS1_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM" evidence="14">
        <location>
            <begin position="568"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="531"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="533"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="656" mass="68457" checksum="01A5036F65B557FF" modified="2013-05-29" version="1">MSFAAASANGIPAAPPTPTGLASLPPKPPMSLNNPRASLGPNERLRQPLSPRVAVSSPSARPTSELLANVTIAQPTPEAEALDQWFENLQNYEVTLEEMAAASLDQNFKEELTAIEEWFRVLSEAERTAALYSLLQSATQVQIRFFIQVLQQMSRADPMTAVLSPSMGGSMQNQMEQKLNQLGLKSPGLKAPSSPAVRNFSAGSANRASFGGDISSFLSPDSAALSDAAGTLAQKRAQLKATQAAHRISAPGLINSNNNVWTGSSLSQVMERQASPSPEPPVSPGLAPATATIRPKSTDFAGVANTLRSPRPNLTEDPPNDGLSPMIGGHWSSMVNTPLVPMFSADNQQNNTNGLDAVNAKLNQWGGAGNDASARVPLMDDAKKFRRKSPAIDEAMSGLRPANGNAALLAQQLAANRSVGADGVNNFNGLGGLSPHMNGLGMGGFGGLAGLQAMGAGGLSPLTANMTGMNLNGLAGMNQMDLLSLNLSPIGLGAGLNLNAAAQAQLLAQLATGGYPNSASSIKFAGLQTPLTAGRPRSAGRRSPSGKVGFNGPASARTDDDIDPNVLQDVPGWLRSLRLHKYTTNFEGMDWKDMVMMDEAALEKKGVAALGARRKMLKTFEAVRIKMGIEGPPPMSAVSTNATSISGGEEPTSAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB43</accession>
    <name>M5GB43_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633043.1">
        <property type="nucleotide sequence ID" value="XM_040767712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB43"/>
    <dbReference type="GeneID" id="63682774"/>
    <dbReference type="HOGENOM" id="CLU_510912_0_0_1"/>
    <dbReference type="OrthoDB" id="2593559at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="291"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="533" mass="57358" checksum="3C8A36F2E0480237" modified="2013-05-29" version="1">MTITSNNRATEDEFVGAEPWSEADALPPPAYEDRPFRNVPGQGSSRGRRRRTGYPQEKRDGTPAPPTDMPVYLPQLTRTPSASSTNSNLTVQDLPITPPRSNREVAAPSVSGATSSSPSQMRQSSIPWDSSRSRASSISSTTSSTSVQACPSATPYSPSGMRVQSASVTKSSAVPVHDGRKSAILSTANLGRPSSLSSTANPIIRDVAPSYPAPMRGSMYITNPDTFDASTPSSAHTTIPPVPHANTSVPSTPLSEPELSQPTPPTITYPADFPSHLARQNGVRIRRAGDVRETFLIDSALPALEGGADKALDIETGSAVDARVYVIGTGAAPSTSEKATEMAFKAASIKMTVVQAIGNPLLKLQFQPEKPRTRAKDPLEVHLCTGVRVSLEAFWPGDCIIRLPPTFTGKVDLRFGKRGTVDIDKNLALRTRILNEEQGVMLFWIGDYETGKGEWEFDKCFIRAEGRISIGVWEADSENKTKTPPAWDTASIASSKRGQALDRIKGVASRIPSVNLYKKLKGNTEKPYLATLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBN1</accession>
    <name>M5GBN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628315.1">
        <property type="nucleotide sequence ID" value="XM_040772855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBN1"/>
    <dbReference type="GeneID" id="63687917"/>
    <dbReference type="HOGENOM" id="CLU_2512590_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9378" checksum="3F49454FA3497768" modified="2013-05-29" version="1">MGFGGLHLRVSQQLSRTLQAKGNALSPTSNTGTTSAFQTFVILSSAPTSIRDLHTYPVLFLLDHHPSSRKPSPNIALHSRLHRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBN5</accession>
    <name>M5GBN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632724.1">
        <property type="nucleotide sequence ID" value="XM_040769713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBN5"/>
    <dbReference type="STRING" id="1858805.M5GBN5"/>
    <dbReference type="GeneID" id="63684775"/>
    <dbReference type="HOGENOM" id="CLU_026393_1_0_1"/>
    <dbReference type="OrthoDB" id="3345970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="599" mass="68452" checksum="A6F4A5E4F8D37D1B" modified="2013-05-29" version="1">MATDGHIRSNAGEDRSLPFTIGSPKPRHWSRRTAFSCFSPAYRWRMLPGILVLLLLVLFFYPTHPPRLAPLPGEWIDPISPIARLRNGGPGRRGDGQVCGVRARMAVEGGGWTMSRIREMVAETEGFFVRDWSLHLGWNNMRYIIESGINQAYVLNRTLVLPSYVYARHCELAAEVCGSYGGVLNRTAFGAHLPISVIELYRMPLGAMLDLDIIRAHRNVVLMSEYLDLQDLPHSLEPITGRFSSDLVPQGATVQTIDPWHYDGDLVRVDRLPPPYTENRKWEYSAEVAEQLEVHTHNGMFMQWENGWRVVSEGKGPGFSEQDAEQVLAVYGYSVIHSYTGRRVEHLKFVGFPVKFICVRDRMRGWYDDHGSSPATVFWLQGEVHVERRPGDMWFSTPAARDEYTELVLYTMHRPANILKVASRVDMRIRQLVGGKMWMAVHMRRGDFTQVDWVRVGSIQEHWGRVNERLKQGRALLRELRHKPKETYDVPAVQPYSGWKGAYPPADDDPFFLATDERDPEYLAFLRNHSAILINDLLTSEDRQELGWPIMMTDFLGLLEQAILARSAYFIGRMESSVSGGALNMRAAWGMDPRTMSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC23</accession>
    <name>M5GC23_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632919.1">
        <property type="nucleotide sequence ID" value="XM_040769518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC23"/>
    <dbReference type="STRING" id="1858805.M5GC23"/>
    <dbReference type="GeneID" id="63684580"/>
    <dbReference type="HOGENOM" id="CLU_1012014_0_0_1"/>
    <dbReference type="OrthoDB" id="5362978at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="275" mass="31747" checksum="FFD395199BF71261" modified="2013-05-29" version="1">MRMMRHTINAIESEEMEDEDEEETVAFRRDLAGRVQALHVQPDPTNDPPEFTWPPEVYESLEQVSTIPESVAPEFLWYPMANMVLAAMFPPGSGFAVAPQVIPTNHSTKEAEDYIVFWVRLVLPGVAANGRGVAVVIWEAKPVQFLRQPVSQREADDQMRERLINMKASMTVPLLIGISSMGPRLHFYTMFRDGHINPPAPPQGNLSRLERFWDIPHHRFDVERRSGCEAMRLVRDICNDMVAQRFHIREMPADERMEEIRRRREARPRPAPKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCK7</accession>
    <name>M5GCK7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_15827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628725.1">
        <property type="nucleotide sequence ID" value="XM_040771142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCK7"/>
    <dbReference type="GeneID" id="63686204"/>
    <dbReference type="HOGENOM" id="CLU_556880_0_0_1"/>
    <dbReference type="OMA" id="DMLWYGH"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067743" evidence="6">
        <location>
            <begin position="22"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="493" mass="53644" checksum="6F4E0BABAF080C21" modified="2013-05-29" version="1">MYTTLSTVLSLLVVLSGLSAATPVERTPSSWPWTHWAPKLPITHYPRPFWFPSLPPPRWPYPIPPVSPHPPGNPNAPGFPECANQFYVNTSALPLINFELPGTWAGLLPVSQSPSETKKLFFWYWPSTASGGSESLTIWLNGGPGCSSLTGFLMENGPISCKSGDAPVLNPYGWTTASDMIYIDQPVGTGYSVGTNDITTMTQLADQFYGFLENFYENFPALLQKPLTLAGESYSGKYLPYIAQRILSTPSVLPIKLNDPAAAYAKEFQSALMLSDDVVSQLVNLSSSCGYDSVMSQITYPPHGLINIPADAYTDACDTWDYMLYSCGNPCLSPYNVDDTCPLGADNTPAYFSRPDVMQLLHVPNMTFNECNPNGVFATSDGYDTSAYSETLLPALLPHLPRGITIEHGYMDALLIYTGDRIWLQNMTWGGKQGFQTAPGSSIASIDGEGGGTYANERGITYVELPGAGHLIPYDQPATALHIFKYVLGQGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCY5</accession>
    <name>M5GCY5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysaccharide lyase 14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631021.1">
        <property type="nucleotide sequence ID" value="XM_040772066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCY5"/>
    <dbReference type="GeneID" id="63687128"/>
    <dbReference type="HOGENOM" id="CLU_049744_2_0_1"/>
    <dbReference type="OMA" id="ANDWIDS"/>
    <dbReference type="OrthoDB" id="2395160at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048958">
        <property type="entry name" value="Polysacc_lyase_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124:SF1">
        <property type="entry name" value="DISAGGREGATASE RELATED REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21294">
        <property type="entry name" value="Polysacc_lyase_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067770" description="Polysaccharide lyase 14 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="3">
        <location>
            <begin position="147"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="392" mass="42125" checksum="A7509D4611427170" modified="2013-05-29" version="1">MARFTTRSVWLVLFFAGRPSHIRATDPSTISASSLANLYQLFTSSTLSFPSTTLSQPSTVSYVQSSWLLANNLVESGQTDMLFVESPNYAVGMKRDERALNDEEASSASTSSRKTSTTTKSTSTVNAKALSATTTTTMTGTTSLPTPAVLQITYPANSYSHQTGGAEFYSLPFGSTTQYTTMLLTYEVAFPPNFNWVQGGKLPGLRGGPDRVGCSGGAQPDGSDCFSVRLMWRPGGAGEVYAYIPTTPAFCSQSEIICNSDYGVSIQRGAFHFSPNTWQTISLLVQLNDPSAANGLVELYVNNHLAISQPGLVFRTNESIASIGGMFFSTFFGGSDPSWATPTQQYTYYRNVELRAGTPSNNNGNGGTSVIGSTWLELVALLTTIVLGIFMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDD9</accession>
    <name>M5GDD9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631351.1">
        <property type="nucleotide sequence ID" value="XM_040772179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDD9"/>
    <dbReference type="GeneID" id="63687241"/>
    <dbReference type="HOGENOM" id="CLU_2984467_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067633" description="Secreted protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="58" mass="6192" checksum="2AA2B0D5273BE9D6" modified="2013-05-29" version="1" fragment="single">MPLALLLLLAPRPLPGSPLTSPSLPLAFLPLPCVPTPSEPNSNRNSSRIRPSNPREVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDZ0</accession>
    <name>M5GDZ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF292-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_50728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629717.1">
        <property type="nucleotide sequence ID" value="XM_040775006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDZ0"/>
    <dbReference type="STRING" id="1858805.M5GDZ0"/>
    <dbReference type="GeneID" id="63690068"/>
    <dbReference type="HOGENOM" id="CLU_037652_2_0_1"/>
    <dbReference type="OMA" id="HEVREFT"/>
    <dbReference type="OrthoDB" id="29853at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.60:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein IST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="27468" checksum="2CF87D2ADA53775E" modified="2013-05-29" version="1" fragment="single">RLAVQRLRTTQEKLTALQKSNRRDIATLIERDKLETARIKVESLIHEDVYLELLELLELYCELLIARFGMLDVLAREPDPGIAEAVNSVIHAAARTEVKELHVLRELLTHKYGREYSLGVMENRDLCVPARVTSKLGLGMPPRELVDAYLGEIAKGYGLNWTPPGGGGGEGGVREEKESKDEQEIEEQLEPPLPAERDPNPLPSVPVENTSKPAVQFKPSSPAKEKDQEDEFEALSKRFAALKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE35</accession>
    <name>M5GE35_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome complex subunit SEM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_98754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DSS1/SEM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631941.1">
        <property type="nucleotide sequence ID" value="XM_040777546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE35"/>
    <dbReference type="STRING" id="1858805.M5GE35"/>
    <dbReference type="GeneID" id="63692608"/>
    <dbReference type="HOGENOM" id="CLU_141774_0_1_1"/>
    <dbReference type="OMA" id="TTQHLWE"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007834">
        <property type="entry name" value="DSS1_SEM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771">
        <property type="entry name" value="26 PROTEASOME COMPLEX SUBUNIT DSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771:SF0">
        <property type="entry name" value="26S PROTEASOME COMPLEX SUBUNIT SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05160">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01385">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12324" checksum="D794BE3C5DA18939" modified="2013-05-29" version="1">MSSTTPAQNASSSTPAEKPKEEKEPLPQLGALEEDDEFEEFETQDWEDPETDLAFLKSDPSAPPNASGSSAQPDSLWEENWDDDDVDDDFSKLLRVEIEKTSQGKDTEMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEE5</accession>
    <name>M5GEE5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_92714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632251.1">
        <property type="nucleotide sequence ID" value="XM_040777101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEE5"/>
    <dbReference type="STRING" id="1858805.M5GEE5"/>
    <dbReference type="GeneID" id="63692163"/>
    <dbReference type="HOGENOM" id="CLU_1015846_0_0_1"/>
    <dbReference type="OMA" id="ACQETRS"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="146"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="29953" checksum="47A8E805555FB58C" modified="2013-05-29" version="1">MVSPQAQAAARAAYRAIFRATTVTFKGDEPLLRAFRQKTREAYVANRSLADEAAYAGAVKHANDVAEVLLKNVAQAKQREDGSWNLRMTEHTELGDNETINRFASSKMSRDRPRGTQMRAFSTFLPRQSYTRDKREAHQKRELPVLKAEDLEESFVRGSGPGGQAINKTSSCVSLIHRPTGIRVLAQPTRSRQQNRKIARKILLDKLDQLMNPGLSKTDMKRDKIRERKRQRDKKRRKEVGDAEDEIEDDLKNPLRMGLPRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEG2</accession>
    <name>M5GEG2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_88207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630112.1">
        <property type="nucleotide sequence ID" value="XM_040776840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEG2"/>
    <dbReference type="STRING" id="1858805.M5GEG2"/>
    <dbReference type="GeneID" id="63691902"/>
    <dbReference type="HOGENOM" id="CLU_027074_7_0_1"/>
    <dbReference type="OMA" id="EWRYEMR"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000036">
        <property type="entry name" value="Serine/threonine/tyrosine-interacting protein a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="224" mass="26022" checksum="D77E19EC0B475A3E" modified="2013-05-29" version="1">MSYIAQQDMPALPGKEWRYEMRRECQEIIPGLLLGPFQVSKDLDTLLALGVTHILCIRDPKEAFLVKARFKDRFQYMVLDVMDNDDQNLISLFSEPKQFIYDAINGGGTVLVHCNGGISLSPTFVILFIMQHNSMSYTEALHYVQNKRYCISPNTGFMAQLKEYEPIYRAQKAILAMPQRPDRMISNRRKRDEDEDDELEWNSRRPHGPMDQHEEEDQAMDIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEK2</accession>
    <name>M5GEK2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_15170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630227.1">
        <property type="nucleotide sequence ID" value="XM_040771080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEK2"/>
    <dbReference type="GeneID" id="63686142"/>
    <dbReference type="HOGENOM" id="CLU_787599_0_0_1"/>
    <dbReference type="OrthoDB" id="10398351at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="38766" checksum="FC8054F7F43E147E" modified="2013-05-29" version="1">MDRKGKGKSKAGYKPLPTDGPVSSEPDMELTTLTGPPPAQGTARFPTRYLMDDYRLDDERKNEREEDQHGVPYHEKQWPMHRRVWRKRWCEWRVMLLVFLATLVFGTMVWAISAAPGPRGPDSPTGDTVIAFGSDLGCTAPHFFNDPRNANLTIGNTTWIHIGIPPSGEFTLTTLGWIATGTISITWDRSLPSDLASLGISLASQDPGFFDWTIQYGSEFPGLYLEVYDEANDMRNCVVYNLTLGLPWEISTLTLDLRSRAQVRVTPPANVGVDDGSAALPAHTLEELHAQFSSNRTGSLLLLSEGLRTERASIDMAIGEITGSWPKPKALNLSLGEGVTIGAGFELFPFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF17</accession>
    <name>M5GF17_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_13763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632791.1">
        <property type="nucleotide sequence ID" value="XM_040770994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF17"/>
    <dbReference type="GeneID" id="63686056"/>
    <dbReference type="HOGENOM" id="CLU_1677832_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="157" mass="18359" checksum="0393E136236F1BC2" modified="2013-05-29" version="1">MYLDVPSITVALNECNETYLIPLSECLDWKMLQNSLWNLFPNFTGRQFKVYATDGSRIPKAFYMHYAKDSAHFYVELKGTDHMISMHVELPEDYEGYFNMHLSPTTKLSDVKKYITSCVDICVDDMRFRKMKRRLEDDESIEEAESTEGNVITLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF29</accession>
    <name>M5GF29_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynamin protein dnm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_49126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630677.1">
        <property type="nucleotide sequence ID" value="XM_040774884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF29"/>
    <dbReference type="STRING" id="1858805.M5GF29"/>
    <dbReference type="GeneID" id="63689946"/>
    <dbReference type="HOGENOM" id="CLU_008964_5_0_1"/>
    <dbReference type="OMA" id="KICHNCG"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000383">
        <property type="entry name" value="Dynamin-like gtpase dnm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF235">
        <property type="entry name" value="DYNAMIN-RELATED PROTEIN DNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="22"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="698"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="504"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="789" mass="86607" checksum="C64EDD4B8A53E0EC" modified="2013-05-29" version="1">MDNDLIQLVNKLQDTFANLGGELDMPQIVVVGSQSAGKSSVLETIVGRDFLPRGAGIVTRRPLTLQLVHIPPPDPDNPTASSYAEYGQFLHLDKRFTDFGEIRREIEAETFRVAGQNKGISKLPISLRIYSPKVLDLTLVDLPGLTKIPVGDQPSDIERQIRNLVLEYISKPNAVILAVSAANVDLANSDALKLARSVDPQGRRTIGVLTKLDLMDAGTNALDILNGRIYPLKLGFIGVVNRSQQDINSERSMDDAQAHEKEFFQNHPAYRSISHRNGTRYLAKTLNHVLLNHIREKLPDMKARLNTLMGQTQHELDSFGDAALFDGQHQGALVLKLMTSFARDFVSSIEGTSSDISTKELSGGARIYYIFNDVFGHALESIDSTSNLTTQDIRTAIRNSTGPRPSLFVPEVAFDLLVKPQIKLLEGPSLRCVELVYEELVKICHNCTSTELQRFPRLHARLIDVISELLQERLGPTSEYASSLIDIQAAYINTNHPAFMQNSAHAHAHHQRRTAAVPPPITSTDMNGSVSAEEEEADDEHSEVMPNGTAPKDTRSVSSTVHDRSRAPSFVPSGAKEAPPMHNMARHDRRSTSGGAQLGVPTVNAGTSPASAKETFLNYFFGGNQPGMPPGASPAALMVPRHSQVGRDLNPESGVPSSALQAVRTLDGSNAAFDMKSLGKHIEAVSAAPLSVREEMECSLIRSLIASYFDIVRQTIQDLIPKSIMHLLVNHTSQQVQNRLVSSLYKPELFADLLHEDEALVNERARVKALLDAYKEAFRTLSEVSLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF66</accession>
    <name>M5GF66_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630782.1">
        <property type="nucleotide sequence ID" value="XM_040769949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF66"/>
    <dbReference type="STRING" id="1858805.M5GF66"/>
    <dbReference type="GeneID" id="63685011"/>
    <dbReference type="HOGENOM" id="CLU_658928_0_0_1"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="417" mass="47263" checksum="7809BFBBB7BAD234" modified="2013-05-29" version="1">MTLDSVFVADHLQSTTTCYIQTLPFELLSHVFIICEQNYNAALTTPPDLRHNSCAFVLRSVCKQWNEVALCTPQLWTRIRILGPRTLALAEMWIQRSGAQELDISIILSSPTEIAASNALIEPHLSRIVTMHFGMTCGTTIYTPAQPAPLIPDTIRSLRFANIGFSNCTALRRNLSLFQRLKYLDLSSSSTDEKWMSVDEIRISRPDWFLMEELEEILLPMNALCERVRQYLLAPRLRYSSIRGHYFAPSPANTLIVREDLSSEQGPLGVHIVLLQVPEVESLTLIWSNRTADFLKPTFCDYALHCLGMKRHAFPLPDMSLSEDEWTDPPQMMLPRLRNLRMCNVPRIGTVDALYDRYVPTYTGSLPAVLERVEIDGPVEPTTWPAVAKTLREHGTTVIESFGTSIFRLQGNEPLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFB7</accession>
    <name>M5GFB7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator complex subunit 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633021.1">
        <property type="nucleotide sequence ID" value="XM_040767706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFB7"/>
    <dbReference type="STRING" id="1858805.M5GFB7"/>
    <dbReference type="GeneID" id="63682768"/>
    <dbReference type="HOGENOM" id="CLU_713759_0_0_1"/>
    <dbReference type="OrthoDB" id="2536675at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="43059" checksum="B43EA1EEDFA7067D" modified="2013-05-29" version="1">MGYNVGRNGGYDQTLKASSSLSQPPPSMLARWSNSNQQDLDVVCQRIVRTGGVHKGRWLLLMRTYRSTAPTASGIRGERIMHTVTPMGVSDPCTYVWLEDGSVPSRGEYRLQLAEKGAEEAARSRMAMLKDEEPAHFRTTFVTLKPPNSLDMLLTNLRASWIPGRQVGEREGWNRAWQAAGNAPHLTLDGFVFQIGLDWIVRVGNLSSPAGGAKGMILEAEYLPLVHMPPREDGDVTKLNDFLSSFLAGLFPASPGARRTVAAMEENLWVEASAEDIFENLYVVDEQKEQLEKPFVNGVSESQNAKVEMEVDKVLETPVDGEKGEEDNGDMAKTDEVDGDDIVLTEDDWVYGTDTVPPPDRRDWVGAEKDRRSAFSIMFVLRRENIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFI7</accession>
    <name>M5GFI7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphinganine-1-phosphate aldolase</fullName>
            <ecNumber evidence="14">4.1.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Sphingosine-1-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_20784</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.27" evidence="14"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631052.1">
        <property type="nucleotide sequence ID" value="XM_040772082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFI7"/>
    <dbReference type="STRING" id="1858805.M5GFI7"/>
    <dbReference type="GeneID" id="63687144"/>
    <dbReference type="HOGENOM" id="CLU_028929_1_0_1"/>
    <dbReference type="OMA" id="FKDHQFT"/>
    <dbReference type="OrthoDB" id="10254570at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008117">
        <property type="term" value="F:sphinganine-1-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000020">
        <property type="entry name" value="sphingosine-1-phosphate lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF6">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 17" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="18" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="16">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU04158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="548" mass="60381" checksum="4B4993E882CA2A63" modified="2013-05-29" version="1">MSSQVVRRTSQLPWKAIALTLKIYDQAKSSVFWNVFWNYVLVRAFWTLRAKGFAGVADDAKTWILELFTKIAFRIPPIKRKIDKEMAKVRDDIEAKIAPRGPGIVRHLAIPLEGKTPKWIEDEMERMDKQERGDIWKEGKMSGGIYHGGEELNDLLVAAFKKFVVSNPLHPDVFPTIRRMDAEIVAMCLRMYNNPSGAGTTTSGGTESILMSCKAHRDWGRAVKGIKDPEIVVPVSAHAAFYKAAAYFKMKVQMIPVDLITRKVDIERVRRAINPNTVLIVGSAVNFPDGCMDDIGALAKMAKKHKVGMHVDCCLGSFIMPFLEKAGYPVDPFDFRLEGITAISCDTHKYGFAPKGTSVIMYRDAELRTYQYFSMPSWPGGLYGSPSMAGSRGGAVLAGCWAAMQYMGQDGYLKSCKEIVGCRRQIELAIRDDIPELEVLGEPCGPVVAFTSDIISPMEVGDAMGTRGWHLNALNGPPAVHIACTRLTVPNVEQFIADLKDAVAEVKANPSKNKGTMVALYGLGQSTAIGPALVTQVANAYLDTMYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFU5</accession>
    <name>M5GFU5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631337.1">
        <property type="nucleotide sequence ID" value="XM_040768099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFU5"/>
    <dbReference type="GeneID" id="63683161"/>
    <dbReference type="HOGENOM" id="CLU_1085950_0_0_1"/>
    <dbReference type="OMA" id="DWPPVPW"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29496" checksum="9C0F2504EB6B0C50" modified="2013-05-29" version="1">MAVSEDWGSLSDPDVIEARDVYYNIGIRPLPKDRYAQEQWNMAQLHTCVMNRLEGVYKNATHIAPHDFHNYWAVAYDAVHFLHEHHETEEGHYFPYFDGGNLMIANENQHAEFAEPILETLAYLDSVNPSKPEAQPFFASKFRASVDRWLVTAAKHMAAELGTLDAEHLKRSGVTVHDMDTAKEDVGKHTMSTQVLKYSLPAIMAAVPRDFDFPRELPWWGKFILTPMLAYCFGYGRMKYYWNAKRWEKTAPNPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG73</accession>
    <name>M5GG73_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Replication factor C subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631882.1">
        <property type="nucleotide sequence ID" value="XM_040771983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG73"/>
    <dbReference type="STRING" id="1858805.M5GG73"/>
    <dbReference type="GeneID" id="63687045"/>
    <dbReference type="HOGENOM" id="CLU_042324_5_0_1"/>
    <dbReference type="OMA" id="LKADIMH"/>
    <dbReference type="OrthoDB" id="761538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="40953" checksum="AB7B1B153DBC193B" modified="2013-05-29" version="1">MSLWVDKYRPRTLDDLDYHSELSERLRSLASSGDFPHMLFYGPSGAGKKTRVACVLRELFGAGAEKLKIEQRVFLTPSKRKLDVNVVMSNYHLELTPSDVGIYDRQVIQDILKEIAQTQQVDLSAKQRFKVVVINEADQLSRDAQAALRRTMEKYMANLRIILVANNTSKLIAPIKSRCLLVRVAAPTLEEMETVLGYVAKKERVDLPPEVASKIGAEAVGNLRRALLVLEALKMQHPDLNAEKLEIAKPDWETYCAKVADLIVEQQSAQRILDVRSKLYELISHCIPPSLIIKTLADRVIERVDEALKADIMHWAAFYEHRMRQGSKKIFHLEAWVVKVMSLYKHFTHDIDLTGFDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG94</accession>
    <name>M5GG94_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_20639</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631987.1">
        <property type="nucleotide sequence ID" value="XM_040772015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG94"/>
    <dbReference type="STRING" id="1858805.M5GG94"/>
    <dbReference type="GeneID" id="63687077"/>
    <dbReference type="HOGENOM" id="CLU_060944_3_0_1"/>
    <dbReference type="OMA" id="KARCAQC"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11927" checksum="BA4300484927FBD0" modified="2013-05-29" version="1">MSFKPGDAAKGASLFKTRCAQCHTTENGGGNKVGPNLFGIFGRKTGQVEGFSYTKANVEKGVTWDENTLFEYLENPKKYIPGTKMAFAGLKKDKDRNDLITWLKDATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGE3</accession>
    <name>M5GGE3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small COPII coat GTPase SAR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Small COPII coat GTPase sar1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">DACRYDRAFT_19876</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632232.1">
        <property type="nucleotide sequence ID" value="XM_040771696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGE3"/>
    <dbReference type="STRING" id="1858805.M5GGE3"/>
    <dbReference type="GeneID" id="63686758"/>
    <dbReference type="HOGENOM" id="CLU_040729_6_0_1"/>
    <dbReference type="OMA" id="GLWNKHG"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00879">
        <property type="entry name" value="Sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000161">
        <property type="entry name" value="Small COPII coat GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006687">
        <property type="entry name" value="Small_GTPase_SAR1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45684">
        <property type="entry name" value="RE74312P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="10 21" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 21" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="13 21" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="14 19" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 21" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 21" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU003926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EJU05338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="21453" checksum="D6277D1A0658E64D" modified="2013-05-29" version="1">MWILNWFYDVLSQLGLLHKNAKILFLGLDNAGKTTLLHMLKNDRLATLQPTLHPTSEELAIGSVKFTTYDLGGHTQARRLWRDYFPEVDGIVFLVDSADTERFAEAKAELDALLSIEELSKVPFLILGNKIDAVGAVSEEELRHHLGLYQTTGKGKIPLKDIRPIELFMCSVVMRQGYGEGFRWLSQYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGF8</accession>
    <name>M5GGF8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1479-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_46468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632307.1">
        <property type="nucleotide sequence ID" value="XM_040774705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGF8"/>
    <dbReference type="STRING" id="1858805.M5GGF8"/>
    <dbReference type="GeneID" id="63689767"/>
    <dbReference type="HOGENOM" id="CLU_011148_0_0_1"/>
    <dbReference type="OMA" id="ISEKWHP"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="53418" checksum="D1EFEB11EA2B1B43" modified="2013-05-29" version="1">MTPTFAKPEGDISSVFASLSDRVQELPQRFATLKEQILGANAQQRGKLEASWQRLVTSLETELNEIVRRGSEVIPVLDFSDISSASDSTREEIRKRGACVIKNVVPKEQALEWKDRLRSYIKANPSTKAFPPKDPQVYELYWSTSQMEARAHPNLLLAQQFLMSLWDDDTDRSNPAEAISFDHSATYCDRLRIRQPGDKTFSLGPHVDGGGVERWEDREYRNLYAPIWNGEWEKYNPYSVRGRLRANMDLYNGPGACSMFRMFQGWLSMSAVGAHEGTLLVMPLIRQATAYWLLRPFFGPPGHTTAAAGADLSADYLRSFRLLPKQTSILHGATPGMAQELSALLHPHLRLSKAMTHMPRVQPGDYVAWHCDTVHAVDPEHQGKTDSSVLYIPTTPLCLKNVEYLAGQRETLLSGTPPPDFPGGMGECLHVGRGTIEDAERVGGIEAVRAMGLAPLDLTEARNPRTKALFAAANQILDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGL0</accession>
    <name>M5GGL0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_20087</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632567.1">
        <property type="nucleotide sequence ID" value="XM_040771789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGL0"/>
    <dbReference type="STRING" id="1858805.M5GGL0"/>
    <dbReference type="GeneID" id="63686851"/>
    <dbReference type="HOGENOM" id="CLU_015166_12_0_1"/>
    <dbReference type="OMA" id="KFQELAW"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000096">
        <property type="entry name" value="ADP,ATP carrier protein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="39"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="143"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="243"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU05673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="37305" checksum="9BA2F0DD58371B2A" modified="2013-05-29" version="1">MNASGPEKAKDATKEKALEAADLVKEQVKVVKKRTKTPKDFAIDFMMGGVAAAIGKTVAAPIERIKLLIQNQDEMMKQGRLSTPYKGIIDCTIRTYNEEGFIAFWRGNGANVIRYFPTQALNFAFKDYYKSMFNFKRSEGFWLWVGGNVASGAAAGATSQLFVYSLDYARTRLANDAKSGTKGGERQFNGLLDVYRKTLATDGLIGLYRGFMPSLAGIIVYRGAYFGAYDSIKPLVLTGPLENNFAASFALGWTVTNVASFIAYPLDTIRRRMMMTSGTGVHYKSTWSAAQQIIQKEGFRSLFKGAGANILRAVAGGLVLPLYDQFQLLMFGKVYSAGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGP3</accession>
    <name>M5GGP3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SLC41A/MgtE integral membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_113872</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632732.1">
        <property type="nucleotide sequence ID" value="XM_040769716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGP3"/>
    <dbReference type="GeneID" id="63684778"/>
    <dbReference type="HOGENOM" id="CLU_018207_4_0_1"/>
    <dbReference type="OMA" id="WDPDNVT"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="137"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="357"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="510" mass="54860" checksum="ADDC716CA981C761" modified="2013-05-29" version="1">MSASDVELYAMNGLHSRSNEHVPLSNEEFIELKRQRSGHSHEDGVKGDEEEEEDIFVTADADVSQPFLSNGRSSYPAHQLRTSARPEPALHLIRSILLETLPTLLFTIIGMVFSGELLVRISTWPAFARVPELLILVPVLDNLKGNVEMNLSSRLGTAANTGMLDKRADRRGIILGSLSILQVQALAVSAVAAGVSFGLAMMLLERELEGARPKSGFMEFMMVTSASMSAASLSGAILGSFMCSLILVCRYFRLNPDNISAPIAACLGDLLTMALLGLTSSLLISWIRTVLPIILTIVLLLLLITTVILTIQNPHVRPLLLQGWSPLFAAMIISTGAGLVLEGFVDRYDGFGMLAIVIGGLPGGIGSIFICRLSTALHAEHDYASGSSEKVTVPPTPERPVLVSAILMAVSLPVAVAYLLFVWLAGWMELPILFVVLFAIFLCIVSAISLGLGYLLTHLFWRFGLDPDIYCLPIQSSLVDLIGQSLLVACYEIARLAGASVGMNAVTSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGZ9</accession>
    <name>M5GGZ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_73794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633262.1">
        <property type="nucleotide sequence ID" value="XM_040776025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGZ9"/>
    <dbReference type="STRING" id="1858805.M5GGZ9"/>
    <dbReference type="GeneID" id="63691087"/>
    <dbReference type="HOGENOM" id="CLU_010592_0_0_1"/>
    <dbReference type="OMA" id="HAHREMA"/>
    <dbReference type="OrthoDB" id="5382203at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="788"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="967"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1010" mass="108476" checksum="969C719023E10FA9" modified="2013-05-29" version="1">MSYPNGFEDAPTYLSGHMADVVLSEFRPTRIKPDALRCVNVLLDELLWSIIKSARSVNTDKLKQDGVLRVIPAALGKESVLEAEMELREYWKTSGDSREAYKDMRENPAQFPIAQVFDVLRLKCEANSSLGQAEEEDNLAVEKAEQRLYQAREAPPIEAFAPASLYLTAIIEHICGHIMSCVSRVVARDSSKTSASISDLYAALCEDQSLYNMAKGMNSFQNIEAQHRSTRVQRKGSLTGSLVSARSRAAAASPRPGYEPPSSSPTNTSNRTSGDSSSHSGVMPMLQTQVQPGPSPIRSPSDRKKVPVIYPQIVSSTVSATNGRPSMSVEHGASPVAQQSYQAQQPHRRSHSGMSEHGQRGGGFPFQTDPNMTSVDDGEGSEFEELMRTGSTMKVSLTPDRLRTFEVFAKDRNQRATTRVVTTQPAGQPPESGPFTAPVQQPALPSSLSNSYGGRPGSRPSTGGRSGSPVNDGYMTDSAVGSRRPNSRQTSRTRLEAIPQLPGQRTVQALQLDEYGGRQPAQGPWGQPPSAPAPVSMPAPTPAPAPAPVPQPQVQPPRPRPVERVAIPPRQQPPFLDGPPRKQNYSPGNIAPLYEETDSLAELDERPKPKSIVSPTSPTSDGPPTRVSKSARDLIAFLDEGPPEEPPHLSRSTSAAAGLDNNNPGLKKSASRGFMNSLKGFGRSGAADKASRSGSVGGTEEYNSLRGLVRRQKSSHTLASTAMNSSTVNIPPPSPVRPVPVRIVLDSKDSIPGMSSRYRDNSVGNGQRPTPPVLHRDVPAQDVHAAALPTPPASHESPPMRTFAAYPPGGSPRPPVPPQQRKITPINTAPNSPLSGNDEYNTAPYNTYTRVAIDKVAEQPIVVHSPQNGTPNGAPISIPASSEEQLALLQKLVQASGSIEECRLLVDSFMAQRGVKTDGAASLAPPPTASMPGTPVSVSKPLPPDPEEENKEKAAVDWLLSGDTEYSAAGEKVTHKLARPKSRDRAMGDRKKSRERMRTTSQHKTLVAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNI2</accession>
    <name>M5FNI2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624388.1">
        <property type="nucleotide sequence ID" value="XM_040773912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNI2"/>
    <dbReference type="STRING" id="1858805.M5FNI2"/>
    <dbReference type="GeneID" id="63688974"/>
    <dbReference type="HOGENOM" id="CLU_041869_2_1_1"/>
    <dbReference type="OMA" id="HIQYGRT"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="7"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="176" mass="19507" checksum="51821B2B32F2E47C" modified="2013-05-29" version="1" fragment="single">MSLPPNTCLYINNLNDKINKEELRAQLYALFTPYGKVIDVVARKGTKMKGQAFVVFGDLAGATTAMRAMDGEFFYDKPMHIQYGRTKSHATIRIEQGADAVPFGARSSTTVNGKSEKIVMSRAEGEAADRERAKKEELEGGKRPRESGVEDGAPQAKKNRTEDEDDAVEMEIEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNY8</accession>
    <name>M5FNY8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_24610</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624968.1">
        <property type="nucleotide sequence ID" value="XM_040773757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNY8"/>
    <dbReference type="STRING" id="1858805.M5FNY8"/>
    <dbReference type="GeneID" id="63688819"/>
    <dbReference type="HOGENOM" id="CLU_001493_0_1_1"/>
    <dbReference type="OMA" id="RQWYIRN"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000009">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000078">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="16">
        <location>
            <begin position="14"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="17">
        <location>
            <begin position="684"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="894"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT98070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="965" mass="109475" checksum="9EC786C72CF068E4" modified="2013-05-29" version="1">MGSGYNPIAVESAWYDWWDQQGFFLPVLGPDAKPKPEGLFVIASPPPNVTGSIHLGHALMVAIQDAVSRWNRMLGKTVLFVPGFDHAGISTQAVVERRLYKSTGKTRHDFGREDFIKQVWEWRNHYQERIKSQLRRLGGSYDWSREAFTMDDNLSRAVIETFCRLHEEGTLYRANRLVNWCVRLNTTLSNLEVDQKQLNGRTLLAVPGYDEKERFEFGVITSFAYPIEGSNEKIIVATTRPETMLGDTAVAVHPDDPRYTHLHGRFVSHPFIPKRRVPIITDSIIVDMEFGTGAVKITPAHDPNDYEVGKRHNLEFINILNDDGTFNENAGDFTGMKRFHARVAVVNALKEKGLYIETKDNPMTVPVCSKSGDIIEPVMKPQWWVNSKALADPVLERTRKGELQISPKSSEGDWFRWLDNIQDWCVSRQLWWGHRCPAYFVNVEGVAQDTSDGKNWVVARSVEEAKEKAVDIAEGRPFTLEQDEDVLDTWFSSGLWPFSIQGWPNQTDDFRAFYPSTFMETGWDILFFWVARMAMLGVHLTGKMPFSEVFCHAMVRDAHGRKMSKSLGNVIDPVDVIEGISLENLHKQLYGGNLDEREIQKAIAGQKKDFPNGIPQCGTDALRFALCAYTTFGRDINLEVLRIEGYRKFCNKIFNATKFAMLKFEEGFVPQPTDKPTGHESTVEKWILNKLHTAASDVNKYLQDRSFMLATTAVYNFWLYELCDVYIEAMKPMTDESASATTRRSAQDTLYTCLDAALKLLHPFMPFITEELWQRLPRRPRDETPSIMVSSYPLPDPAFIFAEAENDFDLVFSTIKSIRSLAAQYSLMSNIYTHIHVTASRIAEVFKEQTPTILALTKGCKSIEIVGSQQEIPLGCGSTVVTADVTVHILVRGVVDLDAEIAKAQKKLDVAELNANKVRKAQSQPDYETTIPEQVREANTERLRVLEAEIAALQQSKETFTMLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPD6</accession>
    <name>M5FPD6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_57565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625363.1">
        <property type="nucleotide sequence ID" value="XM_040775452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPD6"/>
    <dbReference type="STRING" id="1858805.M5FPD6"/>
    <dbReference type="GeneID" id="63690514"/>
    <dbReference type="HOGENOM" id="CLU_004495_0_3_1"/>
    <dbReference type="OMA" id="AFFWTWP"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015101">
        <property type="term" value="F:organic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000046">
        <property type="entry name" value="Amino-acid permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF29">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="568" mass="61255" checksum="3C9710A9BB6CAE2E" modified="2013-05-29" version="1">MGVETKEEIEAHNIDVEKAAAQQVTSIFQPGEFGIVEDHDMTDDEARLVALGYKQEFRREFSVWTSFGVSFSVLGLLPSIATTLWYGLGYAGTAGMTWGWIVAMCGIQCVAQSMAELASSMPTSGGLYYAAAVLAPDGWGPLCSWITGWSNWIGQVTGAPSVDYGCAQMILATASVLHPDFVPQAWHTFLLTVLILLIHACISSMPTKYVAHFNSVSTWLNMFILVIVVILIPAATTNLNPRFNNSADVWGTITNGTEWPNGIAVLMSFISVIWTMSGYDAPFHLSEECSNAAIASPRAIVLTAEVGGVLGFAVNLVIAYTVTDIGAVISSPLGQPFVAYCLQVLTVEAALAVTALTIVCSFMMGQGCMVAASRVTYAYARDGVFPLSKQIWSKVNPYTLTPVNAVWMNTTIGILLMLLIFAGPLAIGAIFSIGAIGAYVAFTLPVTLRTFVVGNRFRPGPWSLGRYSFASGCIATSFTLLMMPILCLPTVNGPDLSAQTMNYTCLVWGGPMLLAMTWWVLDAHKWFKGPRVNVEHRMLQKASDLVGTGMHVVEADSDNGHTVTEVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPW5</accession>
    <name>M5FPW5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4396 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110713</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625723.1">
        <property type="nucleotide sequence ID" value="XM_040769111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPW5"/>
    <dbReference type="STRING" id="1858805.M5FPW5"/>
    <dbReference type="GeneID" id="63684173"/>
    <dbReference type="HOGENOM" id="CLU_030096_0_0_1"/>
    <dbReference type="OMA" id="MMAIMIP"/>
    <dbReference type="OrthoDB" id="5398702at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025509">
        <property type="entry name" value="DUF4396"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14342">
        <property type="entry name" value="DUF4396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4396" evidence="3">
        <location>
            <begin position="253"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="397" mass="45119" checksum="597AA18DEFF2F2A1" modified="2013-05-29" version="1">MDSAYEPPLALEIIGTIFIGVALCFSLWIAVDIVRRRGWRTMMAIMIPVYILNALYLAPITLWTYLNWGRPPKPLAANHINETDRDTKLVDAEKGEPHAHMHMTHEGQNMHGPAGHADDEGHGFDVGQADPVHHTDHDLHSMTAHHEHSPRYETNHQGSQIDTHSVHDMGDHTSHNMSKHEAHDMYNPTLNVIVSGHDMSKHADHNLGLQADHKTDDPLDQDKLKHARHDVNPHGGHNISQHMHMMDERPMFATITIAVCHCGAACLLGDIVGEWLVWGVGAQINGRSIWAEWLVDYAFALVFGIVFQYWSIAPMSGEYGPKTLWRAAKADFLSLTGFQIGLFGWMAIFQLAIWQDRLQMNNVVYWWMMQVGMFMGHWTAFPVNWWLIKNRIKEPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ14</accession>
    <name>M5FQ14_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623567.1">
        <property type="nucleotide sequence ID" value="XM_040769426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ14"/>
    <dbReference type="STRING" id="1858805.M5FQ14"/>
    <dbReference type="GeneID" id="63684488"/>
    <dbReference type="HOGENOM" id="CLU_111205_0_0_1"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="22342" checksum="62D23455659D651D" modified="2013-05-29" version="1">MWVDVKKAFVRKWAAFFNGLEDRHGLNPLNKDHLWLLQWLFLPDINDDATQFQNQWNFHTLSLAEGNRRPVDLFISGCIESGARGIDMDMGEDPQYTCDPQRYRAEGEIPAAGSVEGIIPNPGFNSSTEPPSRGDELPHRLNTVDLPVPRCRLTPRQLLELKRSIELYSSRSDDIALTERWRVSLRACTSFNLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ87</accession>
    <name>M5FQ87_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_18557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624476.1">
        <property type="nucleotide sequence ID" value="XM_040771366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ87"/>
    <dbReference type="GeneID" id="63686428"/>
    <dbReference type="HOGENOM" id="CLU_089696_3_2_1"/>
    <dbReference type="OMA" id="HDGEYVF"/>
    <dbReference type="OrthoDB" id="15433at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="9">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="186" mass="21763" checksum="1ED34B231D4EDBDB" modified="2013-05-29" version="1">MTIYGIGTDILRANRIRLLMERRGPLRVAKRFLTEQEFVAFQRLKHPFPPRMQSWEEDTRYMWLAVRFSVKEAVFKAAFPRLKLTWKDVDLKKKWGKPYVRILDPLKKHLIGNIHVSITHDGDYVSTFCVIERPKWTEDGEETEWDDQLAIRGKHLSPEQKPVSFRDAVWGDEKDDARGGGSGQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR01</accession>
    <name>M5FR01_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_59522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624142.1">
        <property type="nucleotide sequence ID" value="XM_040775567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR01"/>
    <dbReference type="STRING" id="1858805.M5FR01"/>
    <dbReference type="GeneID" id="63690629"/>
    <dbReference type="HOGENOM" id="CLU_004552_2_2_1"/>
    <dbReference type="OrthoDB" id="3253684at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="269" mass="29801" checksum="B84DA42A7922F75B" modified="2013-05-29" version="1" fragment="single">PITPCLVAAGLWPSTPVHLVLAFTIKLLAFYLQLFADCMAPNEAFCETLQQFHAVRGVFHCNDKGRPIEDPFCHAWAVATQWYQLGMIMITSHLECALHEAWCLLIPDLLSLQVSEYIHQPTSDSTLCPTCFGGEEWGSNMKIFPDILVQLDGNFHHRCNLSGGTGPSFYSPLLFLDDMYVSKVGCEMEAMQMATQPNAVQKATTLVEEVVAACWDSFKAAQEKDSQGVPGFHDEKGLVVCSCMHDVPLLICNITTPGEHQMYVIALIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR24</accession>
    <name>M5FR24_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 11">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_23630</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 11"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626393.1">
        <property type="nucleotide sequence ID" value="XM_040773316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR24"/>
    <dbReference type="STRING" id="1858805.M5FR24"/>
    <dbReference type="GeneID" id="63688378"/>
    <dbReference type="HOGENOM" id="CLU_024251_2_0_1"/>
    <dbReference type="OMA" id="NWKMHMT"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF41">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="253" mass="27850" checksum="F69B14C3D16F10CC" modified="2013-05-29" version="1">MPRKFFVGGNFKMNGLLADIDRIVDHLNASHLDPNTEVLISPPAIYLLHVRDRVKKGIEVAAQNCYSEKQGAFTGEISPLQIADSRIPWVIIGHSERRTLFGDHDHVVAEKVKAALEEGLNIILCVGETLEQREKGETLKVVEHQLDCVKKEVPAWAEVADRIVIAYEPVWAIGTGRVATASQAQEVHSDTRTWLASRVGKEAAENTRIIYGGSVSAKNCQELATQPDLDGFLVGGASLKPEFVDIINSHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR71</accession>
    <name>M5FR71_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_55465</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 23">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="18">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="18">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="18">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Mitochondrion inner membrane</location>
            <topology evidence="1 18">Peripheral membrane protein</topology>
            <orientation evidence="1 18">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5 18"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626478.1">
        <property type="nucleotide sequence ID" value="XM_040775329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR71"/>
    <dbReference type="STRING" id="1858805.M5FR71"/>
    <dbReference type="GeneID" id="63690391"/>
    <dbReference type="HOGENOM" id="CLU_044838_3_0_1"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1696654at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="16 18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="15 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="16"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJT99580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="233" mass="26759" checksum="65D673780F1166BC" modified="2013-05-29" version="1">MKEFKIYRWDPDTPAQKPTLQSYTIDLSQSGPMILDALIKIKNEMDPTLTFRRSCREGICGSCAMNIDGVNTLACLCRIDRDQSKTTKIYPLPHLYIVKDLVPDLTQFYQQYKSVEPWLKNDNPPDGTEHLQSIEDRRKLDGLYECILCACCSTSCPSYWWNQDEYLGPAALLATYRWLVDSRDTAKAERKEKLQNEMSLYRCHTIFNCSRTCPKGLNPADAIARIKLQLAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR90</accession>
    <name>M5FR90_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylacetyl-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624327.1">
        <property type="nucleotide sequence ID" value="XM_040775538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR90"/>
    <dbReference type="STRING" id="1858805.M5FR90"/>
    <dbReference type="GeneID" id="63690600"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OMA" id="RDPYTCG"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="487"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="600" mass="66918" checksum="DA8B57C657B61B70" modified="2013-05-29" version="1">MPDFHPHHTVPYPFPRDITIPQFILDSDTHPLRPSRLPGSKWLVDDVSGRAFGIEEIRERVERLARAIKERWGVGKGDVACLYSANDVDYPMVIWALHRLGAIVSCANPSYTHSELEYQLEATSSKLLFTSSASLSTALKAASSANLFPPSNIIVFSPVSPARTPAGEFATVQSLVDRGWDLVQNYTELRGPDVGDNIAFLSFSSGTTGLPKAIAIAHRNLIANVLQVAMHERLTERGLRGDDRFALPGDACMGVLPMYHIYGLVMNLHFVLFCGMTLVVCPKFNFKNMLESIVRHHITHLYIVPPQVVMLNPITKQYDLSHVRFAMVGAAPLSKEVTEKFKGMFPRMRMGQGYGMTETCTIVSKVRCRPPPYTESVQSRSFQLQFLFQQESVNGSAGVLIPDTIARIVKEDGSIANYNEPGELWVRGPQMALCYANNKKATEETFLPEGWVRTGDEALMTKEGNLFVVDRLKEILKVNGFQVAPAELEGHLIVHPYVQDAGVVGIADEYKGEMPLGFVVLEHSVSKRAQDPKEAETIRQELRKWVADNKVRYKHLDGGVEFVQAVPKNPSGKILRRLLRDQAEEVVRKRGEAGKTRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRB2</accession>
    <name>M5FRB2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_57856</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625066.1">
        <property type="nucleotide sequence ID" value="XM_040775470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRB2"/>
    <dbReference type="STRING" id="1858805.M5FRB2"/>
    <dbReference type="GeneID" id="63690532"/>
    <dbReference type="HOGENOM" id="CLU_031988_0_0_1"/>
    <dbReference type="OMA" id="MTHYIGA"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF33">
        <property type="entry name" value="ALPHA-GALACTOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="8">
        <location>
            <begin position="354"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="445" mass="49057" checksum="C5B6D4DDAD78767B" modified="2013-05-29" version="1" fragment="single">TTPNGYHSPPRGWNSFGMQVGIRSATHFAMTQNHTIAQCDLLADPDALGGAGYEYCSLDSGWSIGDHGDEHGRIMYVEKQLDLPALADHLHAKGLKLGVYVVPGAFSKDANKTIYGTHIRLNNTFTGHDNGLSRIDFNYTRDGVQQWHDSVVNQFAEWGVDFIKLDFVTPGSPEHDVHLSPDTSGSVIAFHKAIAKASRPMRLDVSWKLEPNVTYYDVSRRNADSMRIDQDINNQRADTFVSWATIQRAIDNCRQYINLHTHSVEPLTIYPDLDNLYVGNAANVSGITDAQRQTMMTFWLGAGANLLIGSDLLQLDDFGKKLLTDTEALDIADFTSQYPRQPRNPGTGGNIAQQLQAWIAGPDVSGEAVVVVANLGPPLGRSGYEDQPSVEGMVEVEVPFASLGIPGIHKVRDVWRHKDLPMRMDGLHVLLGEGESKLFKLTPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRQ5</accession>
    <name>M5FRQ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">deoxyribose-phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_95740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626788.1">
        <property type="nucleotide sequence ID" value="XM_040777315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRQ5"/>
    <dbReference type="STRING" id="1858805.M5FRQ5"/>
    <dbReference type="GeneID" id="63692377"/>
    <dbReference type="HOGENOM" id="CLU_053595_0_2_1"/>
    <dbReference type="OMA" id="AAYCVNP"/>
    <dbReference type="OrthoDB" id="70823at2759"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000198">
        <property type="entry name" value="Deoxyribose-phosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="9">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001357-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="262" mass="28355" checksum="9779BE06B379C06E" modified="2013-05-29" version="1">MSTKRITVTLSDLAKMIDVSLLHPTMTDAEIIAGLEQAKEYNTATACVKPYSIPLAKEYLAGTSVKVCPVIGFPHGNSTTKVKEFEAVEAVEAGGEEIDMVINIGKALSGEWAYVEDEIRAVNDAVTSRGAILKVIFENDYLQDRHIVKLCEICSRVRVAFVKTSTGYGFVKGEDGKYTYKGATLPHLALMRKHTDPSVQIKAAGGVRTLDDLLRVRALGVTRVGATATKAMLDEAVRRGIGKEPKEVEVSFEGTELSAGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRV8</accession>
    <name>M5FRV8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2 6">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_23507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2 6"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626873.1">
        <property type="nucleotide sequence ID" value="XM_040773271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRV8"/>
    <dbReference type="STRING" id="1858805.M5FRV8"/>
    <dbReference type="GeneID" id="63688333"/>
    <dbReference type="HOGENOM" id="CLU_031468_10_2_1"/>
    <dbReference type="OMA" id="KFLVNCC"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="8">
        <location>
            <begin position="16"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="9">
        <location>
            <begin position="167"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="349" mass="39061" checksum="93FEF5C41538BD7C" modified="2013-05-29" version="1">MKQRRVPKWRQPEVGQAHPIESLILTCKAPSTLSALQRLVPRLSSNSTIVLLQNGMGVYEQLVERLFPDPEKRPHFVLASTSHGVWARGPLNVVHAGLGDFSFGIVPDPQKRRDYEASLKSGFSHLQLADISTNPAEDPQSRTLHATIHALLSLKDLNPHWESMPNMHLKLLRKLCVNCCVNPLTAIMNVTNGELLGSTEAYSILRAICKEASAVFRAHSESGDSYLPATLAMAHLTSPKLEEETMRVIGHTSRNFSSMQQDIKNGKIPTEIEYMNGYLCRLGQQYDVPTPANNMMRQMVKFKSSVGKPTPLPPVMKYWHPLGSFDLGQRERQQTTTKDSTQFRRGSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS17</accession>
    <name>M5FS17_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxyacyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_109508</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626983.1">
        <property type="nucleotide sequence ID" value="XM_040768890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS17"/>
    <dbReference type="STRING" id="1858805.M5FS17"/>
    <dbReference type="GeneID" id="63683952"/>
    <dbReference type="HOGENOM" id="CLU_010194_13_1_1"/>
    <dbReference type="OMA" id="IAGFKEC"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="301" mass="31635" checksum="B509659B62C797AF" modified="2013-05-29" version="1">MAEIIPSPSLLATLNGKVAVLTGGANGIGAATVRLLTSLGAKVIFCDLDATHGEALASELGPEKAIFVKADVTDYGEQYALFRTALAAWGKVDVVIANAGIIEQGNIFGLTEDLSQPPSMAVLDVNLKAVIYTARLGVGFMRQTGGGTLVLLSSMGGFRGNPGVWVYVASKHGVYGLMRCLRSVAAPQWGISVNVICPSMTKTGMVDAIEDIWNKAALPANDASDVAMGIATAATANNGDGRPGAAKPFNGKALFISGSRFYEIEDNIDRLEPEWLGEQNSQDLFKLKEALGSGEIWDSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS91</accession>
    <name>M5FS91_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">assimilatory sulfite reductase (NADPH)</fullName>
            <ecNumber evidence="4">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_23203</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627128.1">
        <property type="nucleotide sequence ID" value="XM_040773151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS91"/>
    <dbReference type="STRING" id="1858805.M5FS91"/>
    <dbReference type="GeneID" id="63688213"/>
    <dbReference type="HOGENOM" id="CLU_003662_0_0_1"/>
    <dbReference type="OMA" id="VFHMELS"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06207">
        <property type="entry name" value="CyPoR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000033">
        <property type="entry name" value="Sulfite reductase (NADPH) flavoprotein alpha-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000010">
        <property type="entry name" value="Sulfite reductase [NADPH] flavoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="692"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU00231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1079" mass="116410" checksum="9E1150130A857907" modified="2013-05-29" version="1">MSGSNGSTPPLSAVTTLAPPSPFPITSAEPWSSTPLLQPSLPLPFNLTATKSKSATSLPTTAAHAIEALASSLSSHVFVYDDALGSGFGQESLTWGMEGKAAKGWEMQARPGAGLVLLGRLGSPLGGSTSAASQGGVLTAFVGPQGLGLMSQTLAQLPASGEGGKLVLQVPGLSPLPSGAFTPSLYSLTPALSGVPTDSENLAVILSSTPKESVALAAAAYSVKQHIVHVFDHSSARELTALPAPKPLGGDLSLATAFDRLGVKYFDYFGDACAEYVLVCLNTPLAHALKAFLAQTPRVGLLVIRVLRPWDEVTFLSALPNSARHLHVIDHVADTFDRGILYDDVLGTVLSGSGLTHSAVHKVGLLPEKLVEHTSRPAQLIARLYPALPAPASVHAQAQAQAKKLAFYTAPNSTLQETIAHTFLLSSSVSTRLLSAIDAFSHVGGVALHRMLLHRASEDLASVELPVDNLFPIEQDSADFVAVADASLLKTHAVLSSAHPDAQVLINTSWSAEELAASLPPATLAQVEAKHPHLYTFDLRKAADSLIALDAGKEEAQEELETVLQLVAFLRLYLVGAGGETAVDKVVRAIYGSFVAGVALPDVLKAAWGNLHEIVLPKYEPEEKKTNENPLKYFEFNTIAAASVPAAKPAPVPRVSSWHEAAKLLMFRESTLVPSTTDTTEQPTALRPETEERTYLVKCTVNRRLTPVTYDRNVFHLEFDSTGTGLKYAVGEALGIHGWNDEQEVADFCKWYGLDPDQVISVPLPEGSRGARHTRTIFQTLQQVVDLFGKPPKGFYAALALLAKDRPDAMALRFISSAEGASMFKKLSEFDTVTFADVLRMYPSAHPSIEQLVELVGFIKPRHYSIASSQAVVGNRVDLLVVTVDWATPSGPIRYGQCTRYLAALKEGQKVTVSIRPSVMKLPPSDRQPIIMAGLGTGAAPFRAFMQHRAWQKSHGIEVGPLIYYFGSRHRSKEYLYGEEIEAYLRDGVITHAGLAFSRDTNKKVYIQHKMQNDGKMLNTMLAGEDEGVFYLCGPTWPVPDVYEALVKSLVHHGEKKRTEAEEYLEALKEDERYVLEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS93</accession>
    <name>M5FS93_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_601316_0_0_1"/>
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        </location>
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            <begin position="53"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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            <end position="122"/>
        </location>
    </feature>
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            <begin position="140"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="455" mass="50586" checksum="0FC365AE5FD5997E" modified="2013-05-29" version="1">MANTALASNFRSERDKRKNARRRDRGGIFQPLEKNAMLDMLMARRKSGRLSLSAFPIEDDEEDTAPSTSPSVCDDEFEKEMRCGVLDNPMDSPWGKRRGTNRTNDELEAQCSSPSSIKSTRAQAVRPASTGKIPTKDTTRPPQRQSTSEPEGESAPSEVTIMAQDVRPASTVKMSTKDTTRPPQRQSTSEPEGESASNEVTIMKSIDEKINRRRSVARPASSPASISPPTLPKAPESPQMNKSDTISEPSAEYYDDGWDVAPETSNHKSSWVDESIPHRTFTSVPKKAPKSADWSRKPGRNGLASKAEPTKIRPPRKSLQSPKGRQTKKPTVIAVESDDEEEVTDTVDNFIESFTELHIETESENEDSNDSYVAPEESEESSSSDSLDNRSIGDDDDSDDRLFCSPPVPSPPGTRTHKRNTIPIVVIYPVQPPIRRRRQYNKNTRTRRTTKVASI</sequence>
</entry>
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    <accession>M5FSK8</accession>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_24020</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63688568"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="8838" checksum="A7D18E7B3A2C8A4B" modified="2013-05-29" version="1">MRNRSPATIEYTKVDSLYRQHWQSTSVNADNSEHSVVHSSESSANGKQQTANRLSKPTVNETVKNRDIRALPSLPSITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSX8</accession>
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            <fullName evidence="2">PXA domain-containing protein</fullName>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="2">
        <location>
            <begin position="49"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38290" checksum="CCC5D63465D5BD65" modified="2013-05-29" version="1">MSAQRPVSLHSSPAVYAPVPASTLPLYRRLLFPSLLQATLPPAVFLHGTPELDVATYELIAVILRSHVTPWYARLTRDRTFVPQVSAVIVHLLKEIEGRVLAADLPLLVYTTLPALVEQHYADYRAARLRHSLSSSSSISDCFTALQPHVALSPNSTSVNTEYIRQAIDHVLKTCLLEEDWEAESERTIVREVLAGPVLGGVLPRLAQPWFLFGLLLSAVGKGTGPKVPVSRVHLNVASSNRYQDQPVAKPPVTSMRQMLVLFINTLHSLTSVLHSVVSFLQAISRFLSTLPANKGASKPRYYASSLLLVVAAILNLSARLVSGLLLSYLSIIVALLQPLLDRYACTASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTJ6</accession>
    <name>M5FTJ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625602.1">
        <property type="nucleotide sequence ID" value="XM_040773627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTJ6"/>
    <dbReference type="GeneID" id="63688689"/>
    <dbReference type="HOGENOM" id="CLU_1098473_0_0_1"/>
    <dbReference type="OrthoDB" id="2575973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067299" evidence="2">
        <location>
            <begin position="18"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="253" mass="24523" checksum="8C40D777EC8EDDEF" modified="2013-05-29" version="1">MFIPTLVTLALSLSAFAAPVPQTGDLLTGAVGTVVGVVDGAVGTVVNVADGALNTVDGVLGGLKKRALQASDVDVAAVAAGVVVDANVGVAVVRRTDVEAVFTTLKSDVSSALSQIPLANVEAITAPVVAAALNEVGTALNVATSALGNLTDGDLVGDVPTLVADVVAEVLNTLNGVPASILADPLVAGVLSTVDGLLATVLGLVSAVFSTVLNLLNGLGVLGLVQSLGLSSVLGLVNSLGLGGLLSGVLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTW8</accession>
    <name>M5FTW8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Histone deacetylase</fullName>
            <ecNumber evidence="2 10">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_100610</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 10"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628008.1">
        <property type="nucleotide sequence ID" value="XM_040767472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTW8"/>
    <dbReference type="STRING" id="1858805.M5FTW8"/>
    <dbReference type="GeneID" id="63682534"/>
    <dbReference type="HOGENOM" id="CLU_007727_7_4_1"/>
    <dbReference type="OMA" id="GKIMEWY"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="15">
        <location>
            <begin position="30"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="374"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU01111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="453" mass="51202" checksum="FF2F0788B35115CD" modified="2013-05-29" version="1">MSISITAPTRKRVCYFFDADIGGFHYGPSHPMKPTRIKMCHALVMNYGLYKRMEIFRAKPATKREMTQFHTDDYIEFLGKASPSTAHQFVKEQGKYQVGVDDCPIFDGLFDYCSISSGGSMEGAARLSRDKCDIAINWAGGLHHAKKSEASGFCYVNDIVLGVLEMLRHYERVLYIDIDCHHGDGVEEAFYTTERVMTVSFHKYGEYFPGTGDFRDVGVGKGKGYALNFPLRDGITDQSYRSVFEPIITAVMEQYQPQAIVLQCGTDSLAGDKLGCLNLSMRGHANCVAFVKKFNLPLLLLGGGGYTMRNVSRCWAYETGLATGVELGEDIPMNEYYNYFGPDYKLDVRPSNMEDLNTPSYLNRMQEITVQNLRELGGPPGIGIQEVPRVPMFDDMDENEDEDMENPDDRRPQRLRDRKRMTLWDSQMALDDSDDEDEGGRRNKEDNKTNGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU34</accession>
    <name>M5FU34_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-fucose protein O-fucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_70192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625902.1">
        <property type="nucleotide sequence ID" value="XM_040775917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU34"/>
    <dbReference type="STRING" id="1858805.M5FU34"/>
    <dbReference type="GeneID" id="63690979"/>
    <dbReference type="HOGENOM" id="CLU_032339_0_0_1"/>
    <dbReference type="OMA" id="DYSPMWR"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="57081" checksum="855F6CB5EA489041" modified="2013-05-29" version="1">MAAFRKAHRHQASSLGTFFTNLGTTSESKSPEYFEPPKQDELPAPPQTPSKVRTKKRVPWKFTSLVAGVCILGTAYLIVRMLQAAIDSDHRTEAISDKLAEDTKNESPVRESDAWRWVRGEPTEAFRDNLLPNFKYITSWPCAGWTNDVMALVHLIYLAQLTERIPILPSFAPSHLGQAAGLIPVSDVFNLRRLSERIHLPIIEWRDVKSANSTIVEEIGCWSPWIGGGQSNGQPRDTYLPAALGLDISYTPTPYSMKVYGEGDSHTLYGRLMQLGFPSGRHEALQQVSPLPAPTSGRAFEPDDKLLCFDYLYYTSLDRNFEWYYDWSPQWRLIGRHMAWAPTLQALSEEYLRRHFGVEAKGEIPKFISVHARRGDFHHSCPADDWTCLPSMDQLRERIEQIRNEILRRDGGYVENVLVMSDETDAAWWEEVKENGWSWIDHVVEKTGERYGVWYIPLLDAVFQSSGAGFVGTDSSTMSLIAALRVQDWHDGPVTYLTWKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU42</accession>
    <name>M5FU42_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_116982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628093.1">
        <property type="nucleotide sequence ID" value="XM_040770296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU42"/>
    <dbReference type="STRING" id="1858805.M5FU42"/>
    <dbReference type="GeneID" id="63685358"/>
    <dbReference type="HOGENOM" id="CLU_066707_1_0_1"/>
    <dbReference type="OMA" id="CLGVPWT"/>
    <dbReference type="OrthoDB" id="63935at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29452" checksum="1BEADE69B003B17B" modified="2013-05-29" version="1">MSTQNVLFIGASRGCGFYAALPVLKAGRRATFLLRNPDTLTSNPEFQALTPEQQQNAILVKGDAYVRDDIVRAVDRAGEGMDTVVFSLGVRPSAWPKITWSRGIILDPSQPCARAIAILLSVLQDLNRPGLRLVIISTMGLGEKYKELPFLLRGLFYGWLLKDAHIDKEALEYLSLRSSKYPTPAHTPPEVAIPSSAASLRSDWLDELVIVRPALYTDGNEVPEKVRAAPVVKGSYTISRKDVGGFIARECLKGENKWIGENGVVLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUG1</accession>
    <name>M5FUG1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628273.1">
        <property type="nucleotide sequence ID" value="XM_040772848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUG1"/>
    <dbReference type="GeneID" id="63687910"/>
    <dbReference type="HOGENOM" id="CLU_1859974_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15092" checksum="2B3DD66C116C8C9C" modified="2013-05-29" version="1" fragment="single">MGLTNGNTEWLLRCSHVLNRRIATYIQPAGEFRACAKNVKIGNNAYQTLTGIVVFIRNQSYCLAKHEEVRGFRGPPKLFSIACIGHVRRDGPESLTTKHLYRTGECGSGRDTRRLVCSALADLLKAGSGSREAGKGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUK9</accession>
    <name>M5FUK9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_101348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626057.1">
        <property type="nucleotide sequence ID" value="XM_040767548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUK9"/>
    <dbReference type="STRING" id="1858805.M5FUK9"/>
    <dbReference type="GeneID" id="63682610"/>
    <dbReference type="HOGENOM" id="CLU_427598_0_0_1"/>
    <dbReference type="OMA" id="HEPEAWI"/>
    <dbReference type="OrthoDB" id="2591449at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="640" mass="67756" checksum="D36712E8AA5649F4" modified="2013-05-29" version="1">MSTLDPYPMLPQPQKRLTARRSSAAQDPFNRLQLTPADSVSRLTIVRVPQPDDAPSRPGSVLGSRPGSAASNRDSPRELNRVSSEKRHERALSSESDRVRRSSWGSAASESRRTPFSPFTPIHPDRPTGTPGSGTGFAGSFSRSRAQTSAPAPRLTTQTLTPKQTVDLALSLNNPTSEETATIAELGEADYLPFLDRCAEVQQLVTSPGPTSDLFKLLRKTFPSSSPNTPLLPLPDPAKWTYDQLIYHLTRVPRSSSPDADWSRLLRLCIRSHSEALWERVKGALGIPPELEVEDERDDPSQSWEIYDFGPGADADADPALLFDEDEYEAEPFEARLEPVYHGGSSPLLSPTLEAALSPNLNALSSSMSGLMPDLAELREEEEDEASDRASGRSSPVGSTKSGESAGSRHIHGLRITTAASISSSHASTAGTPPSVTPAGSVGGSAGAGWSPGTGLAAAGLSRAFSTGSMRGFGRLKMTPLEPAEPRGAGGPSVPGGVGEGRPRGATVNVGSLPGGRTEGVLGRSVPSQSHHVQPMSRQQQPQGAYDLASPLVSPLSSPLNTSNSNALNASLTSNSNTHTSSPDPNLVHRGSSERSHVYHPLAERGPGNPLFPSSFSRLSIRPTLSANENKAAHLPGPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUT5</accession>
    <name>M5FUT5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SWI/SNF complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_72797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623934.1">
        <property type="nucleotide sequence ID" value="XM_040775981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUT5"/>
    <dbReference type="STRING" id="1858805.M5FUT5"/>
    <dbReference type="GeneID" id="63691043"/>
    <dbReference type="HOGENOM" id="CLU_023529_2_1_1"/>
    <dbReference type="OMA" id="NFRCNEP"/>
    <dbReference type="OrthoDB" id="10263741at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10568">
        <property type="entry name" value="SWIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="1">
        <location>
            <begin position="181"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="415" mass="47060" checksum="FF65C42B793347DE" modified="2013-05-29" version="1">MDQVGRPSKRRKLGDRNLPAGVDGEEAALYQDLLEMERKLDWVIARKKLDLSDALNKPGKTSRTLRIFLSTQLSNQSWQVAEGDTGPDADFSSISPPAWTMRIEGRLLDPPSRHAARSVKKFTHYLNSLVVELDRDPSFTEGNIIEWHRTAQTLDAEQDGFEIKRMGDSTVKCKIILDIAHSPPRLKVNPDLAAVIGLQEGSLQTIQNMFWNYIRQNGLQEKGDRRKIRPDAALKPLILQTMGQRENFMFHEIPALLKMCLSPADPVVIPYVVRMDSTTVGELKAFDIEIDVDDFAQKMRVREVMAALSPETAQQIQQLDEEISLAVVSVRHSKLKRDFLQSFASDPAHFIERWLSSQARDLKTVMGHESGMRGDLRRSDNFQLPWVEEAVVVHEGIRVSESLAKMMNPTLQAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUZ0</accession>
    <name>M5FUZ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_23917</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626262.1">
        <property type="nucleotide sequence ID" value="XM_040773462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUZ0"/>
    <dbReference type="STRING" id="1858805.M5FUZ0"/>
    <dbReference type="GeneID" id="63688524"/>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OMA" id="WFFVWKL"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="603" mass="65391" checksum="ECC5D209B01154E7" modified="2013-05-29" version="1">MSEFPHYQQPSSLPSSYALMSHFNPELDPEEREVESNGEISSSIEEVSQGISIQQNIDPALAGPFGPVSYAIKRRRTMSAVPTTIRPNRRILSPLPGTPVAPPESPFVDEHTPLLNTEIPDRRDSKEAPRSSWFNFGKELNVLIRYSFPILATQVLEYSLIVASVISIGHIGTDQLAGSTLGNMTGSVTGYSIALGFICALDTLLPTAWTSDDPSMVGLWTQRMVVLMTILLVPMLGIWFNTESILLLLHQDPEVARYAGAYLKYASVGLPAYTYNAIAKRYFQSQGLMHVPTVATVIVAPLNLFLNWLLVWGPEPVRLGFKGAPLATAFSFNLMLIVFIIYGAFFAPKTAWCPVSHRSFTRLGELVSLGIAGVGMTVSEWWSWEIVALAASLLGPSALAAQSVILSTCSGLWQASNALSIAAAVRVGNLLGAGQAREASLACKVSLFMGICAASLMGGLLITFRHNWAYIFNNDPSVVRLVSQILPLCAGFQAFDALATISSGILRGLGKQSHGAVINLTAYYVIGIPLGLWLTFSRHTQLYGIWIGLTVALVYASLVSVILVLRSDWEHEVDKARARFTDDQAQPINGTEEGCTENGSALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV48</accession>
    <name>M5FV48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_95882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040777328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV48"/>
    <dbReference type="STRING" id="1858805.M5FV48"/>
    <dbReference type="GeneID" id="63692390"/>
    <dbReference type="HOGENOM" id="CLU_025221_1_0_1"/>
    <dbReference type="OMA" id="GAMVYNH"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="UBR-box_UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
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    </dbReference>
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        <property type="entry name" value="UBR7"/>
    </dbReference>
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        <property type="entry name" value="UBR7-like_UBR-box"/>
    </dbReference>
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        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="421" mass="47930" checksum="BDB7D610E642F7AD" modified="2013-05-29" version="1">MPSLQDLVNEQRALEEEASQALPWSFSECTYNKGYIRQPVFLCLTCQSPHGICAACSIACHGDHEQVELFPKRAFRCDCPTSSLSHQCTLHQTLMPPNEKNTYNQNYHNKFCRCGRQYLPSEERETMIQCLACEDWYHESCLNLRERPPPRSEAPPRHSKADDDADSDTSDLPPGLLSEDEYDSMICADCVRKSPVLQRWARTSGVKLVVRDKSEAWRVAPSESPRDTVKEETIDVGSTEQTSAETDAVEDKGAVKPEQGLSGSSGTKRAADDELQEERPLKKPRSLCHAPLQSALSRCVYSPDNDNPALESAGDVFLMDGFRLRWCQCPDCLPDFGDQQYLLREEDTYEPPDDPEAHMSIEELGMRMLDRLPRDRVIDGIHAYNQLRDRLTTFLRPFTQENKEVRQEDIESFFSELRAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVC3</accession>
    <name>M5FVC3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Di-copper centre-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_84832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624169.1">
        <property type="nucleotide sequence ID" value="XM_040776704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVC3"/>
    <dbReference type="STRING" id="1858805.M5FVC3"/>
    <dbReference type="GeneID" id="63691766"/>
    <dbReference type="HOGENOM" id="CLU_035914_1_3_1"/>
    <dbReference type="OMA" id="TAMKERC"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF127">
        <property type="entry name" value="TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067223" evidence="2">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="362" mass="41308" checksum="8F8B75619C4B5D6C" modified="2013-05-29" version="1">MGRPLILLCVVALLTGTHLACANGEDVAPRKCDKLLSRREWRTLTLNERAEWIRAVKCLGNIRHPRLSFTPDQTVLHGDHSLYDDFSYAHAVMDSTAHFKPYFLPWHRWFLHLFDSKLRSTCAYTGPTPFWDWSQDHADLFHSPVFDPDPEHGLGGTGDCDSFSEADCVVTTGAFAPSPSSDTGDFTLAWPLPHHLRRNLTLLTGWFEDEQPQNSTLGPSFVQNATLHTTGDFWKFQWYMTLMHNHVHNLVGGDMAGDCPRDLPREDCRGMAIAYTPNDPLFWLHHAQLDRLWSEWQVVDPLNFDAFSGLPLNPTNLSNPHYSPNASTTHLMEFDRLSVSVPVSSMFDHEQWPLCYQYAEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVR6</accession>
    <name>M5FVR6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_25186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624354.1">
        <property type="nucleotide sequence ID" value="XM_040774050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVR6"/>
    <dbReference type="STRING" id="1858805.M5FVR6"/>
    <dbReference type="GeneID" id="63689112"/>
    <dbReference type="HOGENOM" id="CLU_177289_1_1_1"/>
    <dbReference type="OMA" id="HCFREIA"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="56" mass="6619" checksum="F94BDF1F537FCE39" modified="2013-05-29" version="1">MTHDSVWFSRPRKYGKGSRQCRVCAHQAGLIRKYGLDICRQCFREKSKDIGFVKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVW6</accession>
    <name>M5FVW6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624404.1">
        <property type="nucleotide sequence ID" value="XM_040769259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVW6"/>
    <dbReference type="GeneID" id="63684321"/>
    <dbReference type="HOGENOM" id="CLU_470921_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="579" mass="64531" checksum="2E89A9A4C9877507" modified="2013-05-29" version="1">MEAEGDMGHVLGSAGGDVTGMPNIVGASRRESSITKDRAGYRRYSGRVLRSHANPIKPPPPEPDPDWLTELETATHRITTQYKQFCVGTLPCHLFSIEIRDVLPDNPLAGWHSEELIRNTLRHKSELSFSDSEDTGHVALRLPLFKWIFGDILHLKEVGSPSTGRYNEATARTPFDSLLKVMSIPQAVGSVQTSAVAEVKVAISRPRDEDGPMHLLDNNGIFSDFFEVAQSDALMLLHPSREVQILYRLAKSKQVPPAPKETSWKSVFNSEDPLSFILNVTEYNLEDLEGCIAQVEFVMVAMQRLLQSFGLTDVVVFGSVVDPTAVRIFGCFGGDKSDTLYVHLCETLSISHAPHFWRYVFFLSNLERWGRVEFHQMLRGILNTPHSFSPKAWRCDTWLFQRKNARLAALERTREESMEPTDDEGHDGYHEKSHKPGPGGGGPGPSNPSANKRKRNPHSGGKANPPKKAKGCSMPLNKLDGNVSARARSRYVCPVEKTIRNSTTAAQTAGWPRVLKTSLRDHRSAAHIHLSAEEVLRRADMDSSDESDELDDDAEKLKDKASLLDRIMRWKGDVSPTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY5</accession>
    <name>M5FVY5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626687.1">
        <property type="nucleotide sequence ID" value="XM_040773217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY5"/>
    <dbReference type="STRING" id="1858805.M5FVY5"/>
    <dbReference type="GeneID" id="63688279"/>
    <dbReference type="HOGENOM" id="CLU_042688_2_0_1"/>
    <dbReference type="OMA" id="KNGFQIY"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32242" checksum="DF426C72FB4CA43E" modified="2013-05-29" version="1">MPVATSQFVNAELHFLSPTLKEKPYTTSTSGDTNVVVEDHDVLITDLRSLSESELAGFKTDTSGFQWVKDQSGLKGDDFFDEEKIKNEYYPEIDSFLKKTLGARRTFIFDHTVRRGPEPGEKVEFGRDPSRRGPVTRAHVDQSPKAGAERVLLHLGEDAERLSKGRAQIVNVWRPIRGPVQDYPLTVADYRSINSETDLQPTDLIYPNRRGETLSVRFGGHQKWYYISDQQPDDVLLLKCYESEVKEGRALLTPHSAFQNPNAIGKDVLPRQSIEVRVLVFYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVZ4</accession>
    <name>M5FVZ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YqcI/YcgG family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_81373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626702.1">
        <property type="nucleotide sequence ID" value="XM_040776506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVZ4"/>
    <dbReference type="GeneID" id="63691568"/>
    <dbReference type="HOGENOM" id="CLU_067506_0_0_1"/>
    <dbReference type="OMA" id="GVCPHAD"/>
    <dbReference type="OrthoDB" id="3630793at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014988">
        <property type="entry name" value="Uncharacterised_YqcI/YcgG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40045">
        <property type="entry name" value="YCGG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40045:SF1">
        <property type="entry name" value="YQCI_YCGG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08892">
        <property type="entry name" value="YqcI_YcgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="34364" checksum="F26E4BF3EF47C627" modified="2013-05-29" version="1">MFEFTQLVTYLATFLSGALFAMYRSSIEAQIIRLSKSATALSKDLRLSLYYEFHPSEKPLTSLDVTSVHKPGTWQRSAYDNYVSVLLNEDDVFPCVYATKGFKSNDQLYLFIDTDDLSDRNHIRVLANALQYYLPRARALGPNTSLVLLAKETTNPRSMTEYNDAFWKLLNGVAEYDTVPWPSTIPRDIDNDRWCLCFGGEPFFTVIQTPAHEIRRSRYAKGLTIVFQPKWIFDILFSSDAKRAGALAKVRALLAKYDPIPVSPELKNYGDPGSRESKQYFLLDENIPASCPYSRLAPGKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW07</accession>
    <name>M5FW07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_22430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628943.1">
        <property type="nucleotide sequence ID" value="XM_040772794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW07"/>
    <dbReference type="STRING" id="1858805.M5FW07"/>
    <dbReference type="GeneID" id="63687856"/>
    <dbReference type="HOGENOM" id="CLU_053902_0_0_1"/>
    <dbReference type="OMA" id="CPSNWEW"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038955">
        <property type="entry name" value="PriA/CPL1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067374" description="Protein CPL1-like domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Protein CPL1-like" evidence="3">
        <location>
            <begin position="164"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="23529" checksum="96F70DF07AE7169C" modified="2013-05-29" version="1">MLFGRTLAAALLAAAAPAVLAAVSQRTGLVDRTTSCAQGMFFWSVKEVCLPTGSKASASNPPSGKSCPNDYYYHSGYSCCVPEQPNTPQPSQGSSCPNSWPWSQEDQCCKQPQPSPSAPQPSGKYHGSGHNKLRRAGGVMRTRAAMDCPAGLKACSIGFHLGEFECIDPFQDLTSCGGCVAPGESGKDCTDIASAKSVGCNAGKCEVYECQPGFEPSLDGSACVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW36</accession>
    <name>M5FW36_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Chromatin-remodeling ATPase INO80</fullName>
            <ecNumber evidence="15">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_81464</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the INO80 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The DBINO region is involved in binding to DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="15"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626767.1">
        <property type="nucleotide sequence ID" value="XM_040776511.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FW36"/>
    <dbReference type="GeneID" id="63691573"/>
    <dbReference type="HOGENOM" id="CLU_000315_20_0_1"/>
    <dbReference type="OMA" id="FWKKNER"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000022">
        <property type="entry name" value="Blast:Putative DNA helicase Ino80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020838">
        <property type="entry name" value="DBINO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF2">
        <property type="entry name" value="CHROMATIN-REMODELING ATPASE INO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13892">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51413">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DBINO" evidence="19">
        <location>
            <begin position="462"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="721"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="1297"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="161"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="272"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="345"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="531"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1534"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJT99869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1592" mass="179330" checksum="396A132744C8523D" modified="2013-05-29" version="1">MPRWQEFNASSWGAGGSASRVESDQRHYITEVPSSRKRKHFYEGEGQFTGAEGDPGQMRKRHASDIIHQSPDRQSFALATFNDRLIHPGGSRQDRRLSLLEEPLSPICNGALHDSSELVGEPAGEYVSTARRRLRTIENGFERDTNERNEAAYHTLMHGLASSSGHQDGERSHPHHRTDPRQPALSDRAGNSVSAIHSNVFLDASQQSSESGTFIRDLHAHDEGAPMLPALPVSTLSSQYEARQDVRTKTELASPPSVHVVLDAGLGDRKRKLDNEGRLKESKKRRKDYRSPIDQDDSTLKSAQNVPSRSQSGLGLELGTSEREARVQGLDPTHLGLSVEDMIDELVDGPPSQTSHAGTPSLSDVQPLAGSPVPSLVPSARKKPRSIKKVRSIKEERMVTPSPTRVIPFSIPANHQLAPVPSRPESPERLLLPQSPPRHFKKYTLEMASKRAKVVEENTRKVWKNIASSAVPKAHRVYEAFFHARKLQTLRMALASRKERPKAIRSRNAKETAAKSRRIMKEMLTFWKQNEKAEKEERKKAERAEAERARIEDEKREQQRQQRKLNFLITQTELYSHFVGSKLKDAADLETMQTDGPSTVVVGASPSILGEPGENGLQALNFEDEDESNLRAHAAKNARAAVDLAKQRADAFDADVTQQRIEADIAKEPTEAKDDELMNLEARELNFQNPTMLQDAAVVEQPQLLDAKLKDYQLKGLNWLVQLYEQGINGILADEMGLGKTVQSISLLAYLAEKYDIWGPFLVIAPASTLHNWEQEIRKFVPRMKVLPYWGVVKDRQTLRKFWWNRKKVKYNENAPFHVLVTSYQMVLADAQYFQSVRWQYMILDEAQAIKSSSSARWQTLLNFTCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHEEFSEWFSKDIENAAENKSQQLNQAQLKRLHMILKPFMLRRIKKNVQSELGEKIEIDSYVEMSPKQSRMHKAIRSNISVSDLLSKAATSEEGIRTLMNLVMQFRKICNHPELFERADVVSPFAFAEWGRSDVLSYRRDARIFDVPDSTRSPIVVPIPNLLQRDGGLLCVPGWNSQAGSDTHWLYNMMNIWRTDTIEGSILKKGSPFAVLPLIDVSPSQAYTLWEETVIARMTSAASSTRRAVESAPYLFDSDFALHSVMPMCTVQQHRLVNTLSIAEGLPALHAISSDFWEASFLSRAEARCSIDRACAPAPSLYANDRTFVEAQARARAGYVEKSALYGPPPSLLESQDASDAFEQLVPGVAPQGVLALSDRSQVPQTQMRMPDMKRLIYDSAKLARLDSLLRELKEGDHRVLIYSQMTRMIDLLEEYLIYRQYKYLRLDGTSKISDRRDMVEEWQTRSDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPSNDAQAMDRAHRLGQTKQVTVYRLIVKGTIDERIVQMARVKKDVQDIVVGNKQFVEVAGTNEIVNLLLSPEELEQSMDRLKAQAAAEAVNNADVRRRARKAVNMGSRDLWQDDGDDDSFFDQGAANGDFEFDDEDALAVKSKKTGAGKGVLQVGQEAKGKRKYTKRSSDHASAKKTQASRKRGQFKQDAADTHSTGTPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWZ2</accession>
    <name>M5FWZ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_78319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWZ2"/>
    <dbReference type="STRING" id="1858805.M5FWZ2"/>
    <dbReference type="GeneID" id="63691394"/>
    <dbReference type="HOGENOM" id="CLU_014184_1_1_1"/>
    <dbReference type="OMA" id="AWRFVIY"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="294"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="393"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="487" mass="56071" checksum="9DEDC1BC132266D6" modified="2013-05-29" version="1">MDRSLELSERYYSTDDPLDRVMRPDPHETPEERSARLMAEFEAKQRSDAIDESLRQEKLAAKKNKEVKILLLGQSESGKSTTLKQFQLLWDPNLLDAERLYWRPVIFLNLVVSIRRILECLSPRLESEEGRDGRPGTGNSTVSDEETYSRYAELKLKLSPMLQLEGVLLNELGAPAEFDTLNAYDRPSSLPGASSRKRDILVHLEWQQRLAKSKATRGSRAAGLADRMAFADPGDAGTIITACRPELQRLWDDQFVHAAMARRKLRLEESSGFFVNDLNRIARYDYIPTDEDILRARVRTLGISEHRFTPPTTEREVTEWVIYDVGGTRSQRPKWVSYFEDAQAIIFLAPISAFDQNLAEDRKVNRLADSLQLFESICKQELLKSASIILFLNKADLLKAKLHAGVKFNKWIERYGDRPNEFEAVANYLKGKFVELYKFHRTKLSPRDSHELYVHLTSVTDIRTTHAIFRDVKDTIVRDYLRSSKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX48</accession>
    <name>M5FX48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_24595</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624949.1">
        <property type="nucleotide sequence ID" value="XM_040773752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX48"/>
    <dbReference type="STRING" id="1858805.M5FX48"/>
    <dbReference type="GeneID" id="63688814"/>
    <dbReference type="HOGENOM" id="CLU_1099059_0_0_1"/>
    <dbReference type="OMA" id="RRACCER"/>
    <dbReference type="OrthoDB" id="331602at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT98051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="268" mass="29819" checksum="5B87591AE629A022" modified="2013-05-29" version="1">MPPGDVGELNKLRERVERLERIVIQERIARETAEADLRDAQAATAKAEEANEALQQQLFELGEKIGMGRHVPPKERVLQLASNPESDHFAVRAEQLDALRAERDALLTTQQAKGWVPAESWLAVQREKAALELEAKQREKRMLRLKQVFAAKAAEFREAVTSILGYKLNFSGNGRVRLTSIYDKSTALVFQSSEDGSNTGSMRLIGVGERAEQGEMAEGEGISGALEFWVRQRGSIPCFLSQLTIECFEKTTMGRRAGYAVGELEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXA0</accession>
    <name>M5FXA0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_78451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629505.1">
        <property type="nucleotide sequence ID" value="XM_040776342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXA0"/>
    <dbReference type="STRING" id="1858805.M5FXA0"/>
    <dbReference type="GeneID" id="63691404"/>
    <dbReference type="HOGENOM" id="CLU_039636_0_0_1"/>
    <dbReference type="OMA" id="MCESAKG"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="4">
        <location>
            <begin position="45"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="263"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="408" mass="45563" checksum="3D9D1144A5FFD2A0" modified="2013-05-29" version="1">MGSYVARHPSPSNSYGGKLYEAQGHSPQRLVPSSQTPPPGGRHRTPSRNLNPQHPTHAPSQGINYLSYLQPASTPPYAYFCERIVRVNDQQASIFIQQKLKAVDAAERFKIVDAIVEKGLDLMTNRFGNWAVQRCLEDPCTAEERVKVVNVMRGHVVELATSPYGTHVVQKALDGDERCKLLIVNELLMDDPGETLINKHASHVWSKIMELQWEGNVPPIFEYVNHALRGKWAQLACHETGSLVAQHVFENLSEELKRPCVDEVLDNLVLCSKNQWGSWVVQHIVEHGSPEAKARAISILTREILTLATDQQGVKSLDKALKQSDPMVLDGFVRKMAESRVTGKRAIIVDMALTLPGSQFITQVLNMVGKEHRAMLSDALRSHVVTLKGSRTGAKVIWMFEKARSYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXG1</accession>
    <name>M5FXG1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_95339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628056.1">
        <property type="nucleotide sequence ID" value="XM_040777289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXG1"/>
    <dbReference type="STRING" id="1858805.M5FXG1"/>
    <dbReference type="GeneID" id="63692351"/>
    <dbReference type="HOGENOM" id="CLU_882837_0_0_1"/>
    <dbReference type="OMA" id="TRMWESH"/>
    <dbReference type="OrthoDB" id="2586076at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35530" checksum="E2128E466865C80D" modified="2013-05-29" version="1">MQLVSERGLPAGHEERVLFSVSRDLFPSAQGADLDQDASFHFSFDLPETVEVDGEHYLLPPSGKWFHPQLVAEIYYRITVDVSRRGLGRHERIEPDILYLPRTRAVKVLPLSWGLTPNDAKREFIDMTNWATIPLKPHWPKNASATVQATPLTAELRLPSCFFSGYPPLSFHIHLEIPANASSQAQYDLHQLDVAIHLVRQVSISLRSRGEPRTSTTESIVGGMCIYTSRSTATSRDIWGKIGCQVEGQESSWNLAKLVQVMHAAKVEIKPSQGREGVVPKFMHRQRVWMNTDDWADDAPEREGPALGLYRRISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY52</accession>
    <name>M5FY52_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629885.1">
        <property type="nucleotide sequence ID" value="XM_040772356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY52"/>
    <dbReference type="GeneID" id="63687418"/>
    <dbReference type="HOGENOM" id="CLU_2687782_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="8091" checksum="B4ADFEA15EE8BC4A" modified="2013-05-29" version="1">MPSALSQFTNPTVSRVAEAKSYSIVNDPCVSSSVRWDAPYSNTQGRLATAECIARNDRDVGHTFRAIRARESAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYT5</accession>
    <name>M5FYT5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_50136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630080.1">
        <property type="nucleotide sequence ID" value="XM_040774972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYT5"/>
    <dbReference type="STRING" id="1858805.M5FYT5"/>
    <dbReference type="GeneID" id="63690034"/>
    <dbReference type="HOGENOM" id="CLU_010119_10_0_1"/>
    <dbReference type="OMA" id="KIHQYEV"/>
    <dbReference type="OrthoDB" id="406156at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000040">
        <property type="entry name" value="Chromosome 21, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="1">
        <location>
            <begin position="194"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="43337" checksum="58541F5EEC3C172C" modified="2013-05-29" version="1">MPVPAPQLGSYQYVPETKENLDWAELVTIDLSKFHTPEGKKQLAQELISALRNKGFFYVKNFNISQERVNRQFAIGREFYELPLEEKSKYVPDLDAGKFNGYTPAGRRVIDEKSGLRDKIEIFNMPKFNGHFPQAYPELIQSHLAEIEEFARSLHSEVLDPLFELLALALELPEDYFTRIHVYAEKSEDHLRYMKYGKYSTEENSKLSLWTRGHTDLGSFTLLFRQPVAALQIRDPQTEQWKWVKPQDGTLTVNACDALSFLTGGYVRSTIHRVNVPPKDQQHVDRLGLLYFSRPHNDVKLATITESPVLTREGYTQNEFERFGNKVPTMEEWTFAKQKWQRTPQAYRDETHRTATILPGFREKVFDEPTAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYX8</accession>
    <name>M5FYX8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_97487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="13242" checksum="C59B43529BA086AC" modified="2013-05-29" version="1" fragment="single">HFAGSSVIGHLSHLRPTKFSQNAPRNPSARQHAGLCTARSGGRSCSSDCVWVVRDGRCTQCDYEGWRRRVLSSGCSGSKLIRVEAFAKRNRDQEALALAAAQEEEKIAARAEAAQSASRPGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
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                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lundell T."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11808" checksum="AAEA04BE589A240C" modified="2013-05-29" version="1">MLVLQSAHPQSFTFSSGVKTGRRRLLLRDDFKVSPTTMDMVDYYRMELFHSSDLVHLDEPFFVSWDIARTNTAAPRIRSRAAHQGSRMVRTYGSLIRPESPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZI5</accession>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
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                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623810.1">
        <property type="nucleotide sequence ID" value="XM_040774130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZI5"/>
    <dbReference type="GeneID" id="63689192"/>
    <dbReference type="HOGENOM" id="CLU_2904147_0_0_1"/>
    <dbReference type="OrthoDB" id="3262934at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="62" mass="6925" checksum="0BFBEF719B64C6A1" modified="2013-05-29" version="1">MGFYPADYVTVQAATSTTFTAPPQDGSLIFPDWIDWHIERSHDHPYAVLVGENEGEENVSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G046</accession>
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        </lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="18202" checksum="F3CCE51D82098EF1" modified="2013-05-29" version="1">MLIDDSLFELNAESISNVYGTISSQAKLEGKLAEQNRAGRMPLQLSDVKPVTAFPLPDRPISFNDAKELFITSARPARSNNDELSSELLPVSCSEQELGAEGGPEEATAAVPRVDRRKDGNVGVGVSTRSEQRAVVTTGKIQPTRQTVNVLPVHLTVPLSPVPRTVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0A8</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        </source>
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</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
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                <person name="Kumar T.K.A."/>
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                <person name="Nagy L.G."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
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    </evidence>
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        </source>
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</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
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                <person name="Spatafora J.W."/>
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                <person name="Benoit I."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
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                <person name="Morgenstern I."/>
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                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
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            <end position="155"/>
        </location>
    </feature>
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            <begin position="254"/>
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        </location>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
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        <name evidence="10" type="ORF">DACRYDRAFT_115681</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU02654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G1S1"/>
    <dbReference type="GeneID" id="63685114"/>
    <dbReference type="HOGENOM" id="CLU_429614_0_0_1"/>
    <dbReference type="OMA" id="EWDQDRR"/>
    <dbReference type="OrthoDB" id="21550at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="495"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="593"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="320"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
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            <begin position="533"/>
            <end position="546"/>
        </location>
    </feature>
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            <begin position="606"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="624"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="637" mass="69441" checksum="21810980BD3D7538" modified="2013-05-29" version="1">MDSTVPSRSLGVPQDLALLMEMAQEHVAPSVQAPVVLPVRLPIQVLGKVPLAEPEKPDAEHGALSENQDAAQLKLPSEPQVSIADQANIEPSPPEGAESLSDSESESDDGSESESEESDSSDEADGSESVNERSQPQRAKRQPAEVDEADEEPGPTGPAAFASKHEIVIPNVEMPEFEEIGPEEKIEQIGEVMNIVDSVVVVRGRMNSQYQVIDSGSLLVFEDRKVLGFVFETFGAVSSPLYTVRFPSSSLVPSRVLPSLPIFHVPQRSTYIFTRHLLLLKGSDASNMHDEEVEGDEVEFSDDEKEAEWKRSKKLKRRHGDTLERNGPRFREQEQDVGLDYGDSSVPASDLLAARGPPVRYDDEDFGMADAEPVRSRSPTEDTRRSLGVGRDRDGQRDREWVPRSGREEYRGGGRGRGGGRGGWREPAGGRDRGRGRGRGRGGPSNYNNPNNYDRPPPPQSGPHGYSNSTHGDVAGLSGRAMSPASEAIARVTGQYDAGPSQPSYPSTPYGQHALHSPPGPQDTYDPRAPAFSTVSPSPVQSYPSTPMQTQMALQMQMPFAFGGHINPRFAFAPGFLPQVQMQMQMQQQPGMFGMQQQGRGGQGAWGWEQQHPQGGYPPQQGDGEQHDGVGGEEHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1T6</accession>
    <name>M5G1T6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040769283.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3344402at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="199" mass="22673" checksum="A684A22372B2256B" modified="2013-05-29" version="1">MSVIREASGLHWPENGGPPWRVNNQVAIPQHLPIYLDNSSWLDAFLYALGRGNINHDPNSIMHSVSFRFTEMKVSQDTYICAMCRRLWEGRTFENHPCDNVQVIFTSSFFAKWDPTLPATTLADAVTALKIIKPDAEAGKANYVKIWNLVSEFIIYVFFTCRDYVRIDMHRIMSEALLAPVTVSPERHQAIVQILTGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X0</accession>
    <name>M5G1X0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LSM1</name>
        <name evidence="13" type="ORF">DACRYDRAFT_24746</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1X0"/>
    <dbReference type="STRING" id="1858805.M5G1X0"/>
    <dbReference type="HOGENOM" id="CLU_076902_0_1_1"/>
    <dbReference type="OMA" id="DQFANLM"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000021">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 11" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT97752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="135" mass="15199" checksum="E2E18483CD87730F" modified="2013-05-29" version="1">MDSLIPFTTSGSLVDCVDKKVLIVLRDGRKLVGVLRSYDQFANLVLEDSYERIFHGLEYADVWKGVFVIRGENVVLLGEIDLDVEDEVPLVQVPLQQILPLHNAENETRKKNEVEKANILMEHGFVKEGGEGDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X2</accession>
    <name>M5G1X2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629112.1">
        <property type="nucleotide sequence ID" value="XM_040772615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1X2"/>
    <dbReference type="GeneID" id="63687677"/>
    <dbReference type="HOGENOM" id="CLU_696431_0_0_1"/>
    <dbReference type="OrthoDB" id="3351134at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44372" checksum="10AF7D7E91F9C8DC" modified="2013-05-29" version="1">MAVLSAEVMCEILDLAVPRCDTRYNAAAGGAWPAYRELRQLCLVCRSWATYIQYRLFDHVDLGTFDARLAFLRAIGQNTTRSVELKQTTRILVLSGPIFRPGGRRDVADILSQLPNLKTVHMGPGFNLPYLPPSTYVPSNFPSVRSFTVQMSRQSSWEALHELLRKMPTLERLCIHDFNAVGPMPSVQDTPFTFRLREFVLGCPWRCISPTYLRAFLAHSAGSLEVLGLSMSMIEPGLEEVLQRHVSGLRSLALDTAEEATLQPATLHSCRHLEHLVITSSNSDLIPALPPTLRRLQINKVVFSDGQPMSDRFLETLQTSLSSLELISELLVSGTHLGTGWAHKPLDADEGTMRNIDVRYFGLRAECAKGGVRFCTSIDSDDTQWTRFHELFPMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G289</accession>
    <name>M5G289_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_105378</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631210.1">
        <property type="nucleotide sequence ID" value="XM_040768084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G289"/>
    <dbReference type="STRING" id="1858805.M5G289"/>
    <dbReference type="GeneID" id="63683146"/>
    <dbReference type="HOGENOM" id="CLU_079690_4_0_1"/>
    <dbReference type="OMA" id="AKTVACH"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="174" mass="19175" checksum="C12C994E0582A25D" modified="2013-05-29" version="1">MHASAAAPMRRCAMNMLWNTQVENTCVVFRQWHIGNIGEFIASFIAILLLGLLFEYLRVAQVKMEKRIAARMVKERGVEHAPGTESPGEEALLLARASRMGVARVPMYSRVVRALLYASSTALSAFLMLVFMTYNAYLILAVVIGAGLGHFIFEANIDPEAILFGVNTKGAVCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G298</accession>
    <name>M5G298_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ANTH-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_81624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLA2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626894.1">
        <property type="nucleotide sequence ID" value="XM_040776521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G298"/>
    <dbReference type="STRING" id="1858805.M5G298"/>
    <dbReference type="GeneID" id="63691583"/>
    <dbReference type="HOGENOM" id="CLU_004601_0_0_1"/>
    <dbReference type="OMA" id="FQMSVEM"/>
    <dbReference type="OrthoDB" id="10262320at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17007">
        <property type="entry name" value="ANTH_N_Sla2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1410.10:FF:000004">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000021">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035964">
        <property type="entry name" value="I/LWEQ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002558">
        <property type="entry name" value="ILWEQ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030224">
        <property type="entry name" value="Sla2_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407:SF15">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01608">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00307">
        <property type="entry name" value="ILWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109885">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50945">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="51"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="I/LWEQ" evidence="8">
        <location>
            <begin position="864"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1065"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1109" mass="125099" checksum="C98776A420E686C0" modified="2013-05-29" version="1">MSFFGRSQREPQSDFLDEREYDDYGSPAEARATRYGAGTASTVHYPTRPVDKDKAEAELAITIKKATNGDETAPKQKHVRRCIVYTWDYHSSQSLWAGLRVQPILSDEVQTFKSLILVHKVLQEGHPIVLKEAQNQTGWLETCARTVGNDGQKGYGSLIRAYVSFILAKLRFHRVHPDFNGLFEYEEYISLKGIDDPNEGYETITDLMNLQDQIENFQKLIFSHFRGSTNNECRISALVPLVKESYGIYRFITSMLRAMHRRTGDMEALEPLRQRYNAQHYALRKFYYECSNLKYLTGLINVPKLGQEPPNLMDSGVAPDLPARPKDAGAPSGNGFAAPKSPPAAPSPAPDQAMIAEQARMLKEYEDKQAALQQQRSAEEQKIKEQQAREAREFSERQAEQAEREKREREVLENQQRQWAEQQQMWGQQQAAQRVNELERELLGMRGQFERDQMMLEQYDRRVKALEGELSVISNNAGSQIQGKDELIKQLQDQVTLWRNKYEALAKLYSQLRSEHLDMLSKFKALQLKANSAQEAIDKMERMERDIKAKNLELADMIRERDRARFDLDRSKSSQKEELDRIRRELSFANERAEDASRTKSSEVSSMLSKYNRQLTELEDSLRAKQIQIDDLLHRIDEKDAEVERVKQEKEEEIAVLQEGIDQQLQTVADVQQNQGLTDQAYTAQIDTLILDNRKKMNDIIDSILQACVQKVDDAIYELESPSGAGNQTTTPEYTLSLIEKAANNASEFATVFTLYIDGEHGGDHVDVIKGANEFAQSLADVLFNTKGVTRLVNDDDASDRIVNVAKAAGDMGLRFFLNVQSYKLDLMQPQKRKEAVMLNNGQARSALQKLSEALDAIVPKAKAPRPTNGDIGDVVEQEMLSAARTIEAATQRLQELMARPKDPRFSGFDVQVHDSILSAAMAITSAIGRLIKAATESQQEIVAQGRGSSTSQQFYKRNNRWTEGLISAAKAVAFATNLLIETADGLLSGTHSLEQLIVASNEVAAATAQLVAASRVKASLMSKTQERLELAARAVTEACKALVKQVKAISAKKLDEESVDYSKMAVHEFKVAEMEQQVEILKLEKDLTAARHRLGAMRRAGYHTEETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2B6</accession>
    <name>M5G2B6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fip1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_88514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629728.1">
        <property type="nucleotide sequence ID" value="XM_040776861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2B6"/>
    <dbReference type="STRING" id="1858805.M5G2B6"/>
    <dbReference type="GeneID" id="63691923"/>
    <dbReference type="HOGENOM" id="CLU_038604_0_0_1"/>
    <dbReference type="OMA" id="MMDMSGM"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="221"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="434"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="539" mass="57730" checksum="D3F386CDFE3F2704" modified="2013-05-29" version="1">MDEDDAFLYGDEEDYPSVVEAPSEQPPKDPEPNQSIPGQLIVLPNGPAEPFLVASVPAVVVAEDLEEPDELPMEHSEGEGKEGDADGEEEGEEEDEEEDRESEDDDLEIILQPQPRSIDFRDPSHQRPVRPPVASPAKASSLLTTEYTPRERDTSISIPKSTGTPQSTNLIPVTDVKQISTAQVAVENRPIPDGPPPRAASNAPEIDPSASGMLDARSIYEVEIQSLAEKPWRRPGSDLSDWFNYGFDEISWEAYCMRKKELSELSTALKQNVIAYTGMPENQLLALPPEMRTMAINSANMANTMPIGMAQNIMGGMPGIPAGDMMGMPAIGMAGMQPVQQNMMGTAMGPEHSIHMHDNMTGNVQGQGPSIEGMASEGFPYGYSGVQITPGAPVGGSDTNTPGIAQFSTFTGGYGVDASGSHGDHAFPARTTARHTTLGGRGSTPVRGTGVPVRGRGRGAGFAAGENMSTLPTRPASPLPPNVPTGPRNRTTYKDKDREPVKQDVEGLDYGGGIVVEPATSSRKRPYIGEEETGRSKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Z1</accession>
    <name>M5G2Z1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Z1"/>
    <dbReference type="STRING" id="1858805.M5G2Z1"/>
    <dbReference type="GeneID" id="63685107"/>
    <dbReference type="HOGENOM" id="CLU_457835_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
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        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
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        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
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            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="596" mass="64353" checksum="0403CBF70C0B9E33" modified="2013-05-29" version="1">MNVAQSAHLSAAAVVTATAIRRPLSIYFATLVISLSGLILSIFCLAAVTRPPPSRRLSLPLPARPPHQHPTTPRRLTAHRASSSPELNRPSPQFPDPPRPARSRTRRLLTTPTPFLPPLPSPKQVRKAVEGPCRLLGGRALTTATGRALFLRDALDANMREVRARRRARGQGQGGRESLSSYASSCESLSAAEPSEAEEVKEETDEERTPHPLIRTGTGTGVRGIGLALGQGTLSPQEEKEWEDTDPTPRSSPVRRRSLIPSLPLPTPVPTPTPQVQPQGQGQGTPVKEKKHFWLRRSSTISSLPLPLPLPPGLAHPSPLSQICLPEAQPEPEPEKGNRRPLSTSEMKEGEGKRRSSGGSDASLGSVSGKSESARSSASGGSRGSTSTGRTAPPPYTPAPAPAPAPAPAPTLAKHARSRTSLGSPVPPPPQLKPRPTSVIDLSRSRTRASEPLPGEAEREWEKKKGSGFKHRISGIFGHSPSLSRSHGHGHGLAALDGLPPSISESGLPESQSTPEIKPRAAKEKAGVERVGRHEWMQRVERESWRVSYTSREELESGMNDKEKEKEKEKGKEKGIRGEKRMERSPSRWRLSKVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3I5</accession>
    <name>M5G3I5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 20 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_54629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627324.1">
        <property type="nucleotide sequence ID" value="XM_040775276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3I5"/>
    <dbReference type="STRING" id="1858805.M5G3I5"/>
    <dbReference type="GeneID" id="63690338"/>
    <dbReference type="HOGENOM" id="CLU_002351_2_2_1"/>
    <dbReference type="OMA" id="MFYESAS"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="720" mass="81802" checksum="54F04901DD7693D6" modified="2013-05-29" version="1">MQAFDILHNPHGNVGLQNAVHSVSAPDGPLQEKLWVGILGTATDGFDDELKGEVDLRMREESESAVVWLGDDEFDKYYHEFCKRVLWPSLHYAVPDAPRTKVFYSSTSYAQYKAVNQKFAEVIVSNYKPGDIIWINDYHLFLVPQLVRAQLPDAPIGYFHHVAFPSSEIFRCLSVREELLRGILGADLVGFQTHNFARHFRQTVTRILQAEGVPKGIQLDGAHFVDVSVFPIGIDVKAFEEKKRDPEVLEYCSMLAERYAGLKLIVGRDKLDFVSGVRQKLLAFEEFLDKHPEWQGKVVLIQVALSTTEENEQEGHVSEIVTRISSRFSTLTYQPVVFLHTEELTFSQYLALCTMADVFLVTSLREGMALRSHEFVECQTERKRPLVLSEFTGTYSYSGFRSCIAINPWDYRESARAIYTALTMPDSEAASRWEDLHKHVITQTAQSWATSLVSRCERVHEEHRRRPVESIPELNVAQVRGAYNIARDRLILLDLEGTLWHVSNAYLIHTEGFSPPKEMLELLEKVTRDERNRVYVLSGRGTADLEAIGNRVPRLGLCAENGCFVRPPGEKQWRDMVPGFNKDWQGPCVEILQYFAERTPHSFIEKRGASVLWRYYTGDLSDTAALQWARRQSAEAQNHIFDSLGERFGLRIIPGATAFLVLPKNVSRSTAVGSILHIGEDDLSAPLPQGESLPMSPDLEEEEEHFDFILVVSGDERLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3N3</accession>
    <name>M5G3N3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Peptide hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_16916</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627364.1">
        <property type="nucleotide sequence ID" value="XM_040771243.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G3N3"/>
    <dbReference type="GeneID" id="63686305"/>
    <dbReference type="HOGENOM" id="CLU_230761_0_0_1"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000008">
        <property type="entry name" value="Endoplasmic reticulum metallopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="535"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="17">
        <location>
            <begin position="157"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="16">
        <location>
            <begin position="1997"/>
            <end position="2091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="979"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1304"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1368"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1708"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="983"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1716"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1748"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1767"/>
            <end position="1783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU00467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2241" mass="249002" checksum="3BEAEFA731537C0C" modified="2013-05-29" version="1">MAPAHPHPRPAKSLLELLLIMCPLVIGIPWLALHIHYTISHPVICDSLPEPIIEQYHPLTGTPQLSEHHILNTARYLSESIGYRTVGTREHALADVWMSEQLQEVQSLCEEEASRRRERGEGGVECEIWRQEGSGKHRVYKSYHGLTNHILRLSANTTQSKAHAVLVNSHLDSTLPSPGAADDAVCVGVMLELIRVLVHGGWSGEWSIIFLFNHAEESLQDASHLFSTQHPLAPTVQAVINLEAAGTTGPELLFQATSQEMIAAYSHVPRPHGSVLANDVFNSGIIISDTDFGQFVKYLNVTGLDMAIVGNSYLYHTRKDLVENIQPGAAQHMAENVLALLNYLTSARSPLPHLTEYTAPATVYYSLLSSIFFSYSYDLALVMSVSLLFWALALALVTTRDWTVVPRAWAGIVGGMAGALGAANLMAYFFASILCKPLSWFAREWLCILLYAPPALLGAVFVQLLVHPPPARPQIEHQSLTSLMLFYSFVAFAGQMAGIGSSYLYFINALSLWVATALNELLVRVLKHEPGDVNHWTYAVGSVIPLIAGSEALAPTLQTGRLGRDAPVEHIIASIVSFLTFYMAPFVLPFAHRFGRPALRTITLVLLGVSVGISAVFAAPGWREFDRQHQNRFFVVHIENITSHDYGLHVATLNSASGFSEIVNSLAGDFAEVKGVPRLTTELGDKLAWDVFHPVSDLVTSYAMDLSPPEEYVSHWRQEFSVHALDIVLDPHTDTRTFTLHIDHPGLIWTVVSFQAEVLEWDLPDAPVEGHALHKIKEASFYMADQWSIRMTLNGTAPVLVNFVGIEERSMWPGKKARQGENREEKPSMRMFERLETWLEQKSDGGIDVNMFGCIAGAVEHGWERAAGATKVTSSHTQRHAPSKLLYFDGARTLDTQDVLLYGNVSTGTRWNPFGRIVELCDWGKQFGIDGFLRMEFDFEIMYCNFTNGMELISSVNVVPCTWERTPSSVELIEHRLSVPTMGNPPLPEPTGPPRRGPGRPDRNPTPPEPPVGWQGSLRTPSQVTFEALHAGYWHNFAPLTGIKLEYWGLTTFYDPKYGSLVPGRWGLDAAQYRLANISEKDASAWKRELEGVLIRPETEGSGIDWGNIMRHIVERHADRLEFFRHLLRTATRKDGGDRVTPTQNLTKIVENARLQVLTMLSPYLSRAAVPPGKSASNDRAWLEPTVSLCTGSFTQHMNVSRFTPQEHVLKQATDTTAREICRTLGLIWLSAFSAESVTLPSQQEQLLNSWLLEVERLMAWLDWAVWLRCTPVCGDDEICSPPQWPFDGVRTGDEGREPHCISRVDFQRGGRGPGGPDEPESPGGPGEPHPPRGPEYTRSSALLQGSSSNISTQSSLAASSTCTCPDSFVPPSAPRPSPSISRTSDLTDPEATMNVLCDTSAVTATMSGSIEVSASRTLPERRSSDERQSTGLLSSIHVAFEVITIRTELTIEYVPSLNCKYTPDLPNAAWKSLSAAGQSIDGRIPNSFCCMDASPSSANMDDTAQTQLALLPSPIRTAVQNILNYLSRAAETAIGIPQNDEEIVHITERLDYIKQFLGLYPAHLLQSRDNRTDTSNAISPKSNIRPLEPEEQKDLLHHLTREFQRINDLMVKYRDKRSTATRRMAFQPEAAVLVRKMKEASERASTYLLVYKVVDADTTGDRFSRFENFISFHYRDLVRHGPHAMRSKPSLDTLSTWEPRHKIPRQISAPGVSSRAHQSYLPTTRPVSTTPAGRSITPTVKDDLHTRSFRGGRGRGRGRARGKVVNSHNNSQATPTDVDTPNIAEQTGVDIRPAPVSHKESESEFGSPLPQITMSTTAPLVPFLENERFDDVHATRNLGILDAHNDVPSDKDPVIHMVLKHMLTPGGKSKDCSEECEAFAATYKACMTSEVMFSHFFDVSSTLLDRVGSSGLPSILNFVVYWLYHVQVGVEARDLLLRIQSFVLGIQDFVSGEVTKSQTLAILQVLQELPLKKPRVLKRRIKPSTKELEDFEAIQLADQLTILLSLGFRRIQVKHLIAWVSPEEKSETNPVNKFKEVCAKVQSWVKAALLGCSKGSSGRERVKKKFLYIAQRCLESYNLAGTVSITSTLLQLQEAGEIKLRFTREQEGHPINGLVAPSPGEELYWNALASKPADTACVPWLDPHESGLQEAGDDVRTARPISIANHRALFMEAKKLIAYGAKQYEVPFSLQDMSYLEFHFKVSSQDLRDEVKKGELCTNGLRLSWWKPDDRTRLPEAEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3U0</accession>
    <name>M5G3U0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glucocorticoid receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_54061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
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                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
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                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
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                <person name="Pisabarro A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">DJM-731 SS1</strain>
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        </subcellularLocation>
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                <person name="Kallen N."/>
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                <person name="Ohm R.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
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                <person name="Heitman J."/>
                <person name="Hesse C."/>
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                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
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                <person name="Nagy L.G."/>
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                <person name="Patyshakuliyeva A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="PANTHER" id="PTHR34066:SF1">
        <property type="entry name" value="DUF1764 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="178" mass="19683" checksum="586FB82087663CA7" modified="2013-05-29" version="1">MNVRSWQGATLFSVAWRHCHRESPCAPSGTSTSKPARLAAASSPANGLKKKKKQKKAEEAKAGSEQASKDVVTDTTPNPEPKPLKRPAETIVDPSLPRLSKKPKFSSNPLTNASLTTKSKPRKKPELDEEERAFRDSRGNEPRRKTEEGWNVYKEDELGIGKEGGDTPLCPFDYDCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5H7</accession>
    <name>M5G5H7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_46121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632405.1">
        <property type="nucleotide sequence ID" value="XM_040774682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5H7"/>
    <dbReference type="GeneID" id="63689744"/>
    <dbReference type="HOGENOM" id="CLU_026593_1_0_1"/>
    <dbReference type="OMA" id="HYYENEY"/>
    <dbReference type="OrthoDB" id="2404451at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="259" mass="29263" checksum="D8718820A0D29360" modified="2013-05-29" version="1" fragment="single">TAPAQYDPLNLPLCLHNSILHKAESVMQAESHAEAEHHAKASGINGISIWSIIWPTSFPLDFMHLVFENVVPLLLDLWLGVSKHCVEGDAFTLLHAIQTDVAKRVAKSGNTIPGAFGQHVLHLLNKRHEFMAEAYMLRITQLAPVVLLRQFTNEAYYHHLVELSCFINDCLSFSHHAGFMTMLRKCLVKWVLQYKQLYYQGSTDHVGLCPVTVHSLLHLADCMEWTGPLWTTWAFPMERFCSQLQCAVTGCLNPYPGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5I0</accession>
    <name>M5G5I0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_17687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625910.1">
        <property type="nucleotide sequence ID" value="XM_040771297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5I0"/>
    <dbReference type="STRING" id="1858805.M5G5I0"/>
    <dbReference type="GeneID" id="63686359"/>
    <dbReference type="HOGENOM" id="CLU_011862_1_0_1"/>
    <dbReference type="OMA" id="DQQCSAK"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46275">
        <property type="entry name" value="HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46275:SF1">
        <property type="entry name" value="HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="11">
        <location>
            <begin position="29"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="10">
        <location>
            <begin position="169"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="430"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="491"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="590"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="515"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="625"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="705" mass="77900" checksum="57FACFEE842D7275" modified="2013-05-29" version="1">MASLFWGASPFDDLVDKATSELLPAGGSDIALNLEICDQIRSKSTTLILAMRAIKRRIDHKNPNVQLLALELADTCTKNGGDTFLQQVASREFMDDLASIVKSPGVNRDVKLKILRLVQTWARGMEGNSELKYVGETYKTLKSSGFEFPPESPREAAATLFQTATAPMWGDSDRCMRCREPFTMTFRKHHCRNCGQTFCQSCSSYTSRLDHFGINTEVRVCKDCHDKMTRKTVEAAKRELKKDGIGSRNWVKRERERADKDLERAIALSLAEAKNMGHVDDGAMFRPAVLSKGYPPPTTIAEEDDPDLAAAIKASLEEYQTMNVPSAPSPMPERPGTVESYFPQPPPALPNYDLMDSETLTILDFSEAIENGASARSVDGLHNRADRLRPRLVRSLDDTERKEQILTDMHGKLAEVVKLFDSHLNAQLERRASSYHQPQRTQTYASFAPQRTVSPQASYGPPQQQQYAPPQQQPYAPQQTYAVPQQQAYAPPPLTYQEPVQPPQQSYVQQPPQQMYTSPPKQQQPISTVQAYPSSPVRSNTGIISPPPMQASTSPVMQMSVPQSALVSAQAQPVPAAPPAVTYQAPVSQPHPYMNPPAPPSRQQSYVAPAAPAQPAYVTSPAPSPTQQLPPQLMQAQPPPQQYALAQAPPIQVQPVQPPPQQLPAFPQAPQNVFPSAFPEAPKELPNSFAYAPVREEKEVALIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6B8</accession>
    <name>M5G6B8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_23896</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626210.1">
        <property type="nucleotide sequence ID" value="XM_040773445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6B8"/>
    <dbReference type="STRING" id="1858805.M5G6B8"/>
    <dbReference type="GeneID" id="63688507"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_1"/>
    <dbReference type="OMA" id="FEIFRRQ"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="179"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38095" checksum="5A2288FEAFF57B5E" modified="2013-05-29" version="1">MGDAPLPSSMKALFYHKPEDYEVKQISTPQCGEEEVLVKVSACGVCGTDQHIHLGEFISQFPLVPGHEVVGQIVQVGSRVMGGFKPGMRIVADNGSSCGKCFYCRRGQELLCEDFTSKGCTIQGGFAEYVAFHESKVYEIHNLSDIEATLVEPAACAVHGMDKLRPPVGCDVLLMGAGPTGLILAQLLKLNGAVRVVLAANKGKKMEIAKQLGCADVYVELDREDPAHQWEQLKKDNPYGFDVVIEATGVEKLANDAINYVRRGGTLMVYGVYDNKALVHWPPGKIFGDEITIIGSFAQTFCFPRAVAYLDSGKVNVKGMVTDIYPIDRFGEALDKMASRNCLKIAITPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G740</accession>
    <name>M5G740_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_109675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626475.1">
        <property type="nucleotide sequence ID" value="XM_040768922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G740"/>
    <dbReference type="STRING" id="1858805.M5G740"/>
    <dbReference type="GeneID" id="63683984"/>
    <dbReference type="HOGENOM" id="CLU_785320_0_0_1"/>
    <dbReference type="OrthoDB" id="2152896at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="353" mass="37618" checksum="82B0C84B9B4FCB5B" modified="2013-05-29" version="1">MTSPFSALHDLSALASTLSPSPLVSAAPGPASPIPMHSQSASHAYPPRSSYTPPSEASYSSTPSLSFSASVQGTSPYAPSLAGYATANPAPGGLAAAAGKEHRKHRRQSSSSGHKRRLSDARDALSMTRAFMTADSPPLGPTLTSQSVPATSYLSARGGSTTKRESSKSNSDDGAELMPKDSAGKKLYICDDCQKVYRHRSCMDKHRWEHSPQWLQSSKFLLSKHQQVQLLEAATILSHLSAPSQSLPEDRSLWPKYLAEVTTPVGSAPQSGMGRPAHASKWSVPSNGRKSVSAYDGESVLGEIDMDDASEDLDVVGGDGDDRMSMEDDDEETEDEIEVVRPWTGVGGLEMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7F6</accession>
    <name>M5G7F6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <location>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5004067631" evidence="1">
        <location>
            <begin position="20"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU04664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="17955" checksum="B59992B6BA8CED9E" modified="2013-05-29" version="1">MYRSTPILILLALLPQILAQWVTQTQIDPDSGITYLDRVSYSRAGAAVATQILSTFGDELLAAATTTGPPRIVGQPGTNTGAATIVFQFTSADGNVYEATFTPTYQSPSPTIPPQVGTIISPEDWTFTQAAAVTGPAVTSGAERIWPLAQWGRVMGFVGAGVVIGAWWVL</sequence>
</entry>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
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    <dbReference type="OMA" id="IMMANDR"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0016491">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
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        <location>
            <begin position="6"/>
            <end position="261"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU04125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="36900" checksum="FA80A9854162C443" modified="2013-05-29" version="1">MATKLEKVLLIGSTGTIGYHILHAFLPKVASFKRVAIFTSQNTVGTKKELVDKVKASGVEVIVGDLGNEAQVKETFSGFDTIVSALGRGALHLQSNLISIAASLTPPKRFFPSEYGTDIRYSPVTSPSEIPHQNKLKVRAHIEALAREGKITYTYVVTGPFADTFFISRMPRIGLNMGNGTYGIVGPEDAEKQEKISGTTYSDTARYVLSAVQAPPETTKNATLRVSSFTAKPAELLKGFESVLGKKLNTIYTPLDELRKLEKEKWAEKDPYATVYTLNRIWYEGGSDFSRKPVALYLDEKTGEDVEDEERSKHLFEDVPKRSLEEVIKEIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G898</accession>
    <name>M5G898_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_87592</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Copeland A."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
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                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Lindquist E."/>
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                <person name="Lombard V."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="3353776at2759"/>
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        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU04370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="191" mass="21419" checksum="BEE01D88DF7276BF" modified="2013-05-29" version="1">MYSRPGASMLSPSSATVRPGYNPRPRGQSNAAPSGSGMPPDLELFHNFVRWHAPDELLQPWGARYRPPQLNYAGQPIPHDRFSASLVIVEPYGKNAVDVVFVLNRRPPQKRYCVRARVYLQQWAKDERNAQLTTDDVRAAAFRGVQTLLNSPHLEPVEWVTSLAGPTEVEEPATPEMRAENAPSLQWSMSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
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        <name type="common">Brown rot fungus</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
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                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626945.1">
        <property type="nucleotide sequence ID" value="XM_040773289.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G8F9"/>
    <dbReference type="GeneID" id="63688351"/>
    <dbReference type="HOGENOM" id="CLU_001136_3_1_1"/>
    <dbReference type="OMA" id="TEVCTND"/>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="97"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1393"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="958"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1000"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1088"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1035"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1097"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1563" mass="175606" checksum="509FE490025EF08E" modified="2013-05-29" version="1">MANHKTAFREEENSYLRPTNSQRVYTESHRSSYSGSGGSQMSTAQGQEENVEVVVEEEEGVVVLTLTPYFFSKRHLTCGIPAGPPPRTSQNWRSREKLKTTNACLLVCLNIGVEPPDVVKTSPHARLECWIDPFKLQPSRALDHIGKNLQQQFMTLNPRLRYKPCLDPTHDDIKKFCSILRKTAKDERALLYYNGHGVPKPTPSGEIWAFNAKYTQYIPVALAELQQWVGEPTIFVWDCSAAGNVVTNYLRVYEERKRSANGRGSNESLKQDPEADESFYSSIHLAACDANETLPMTPDLPADIFTSCLTSPIEMALRFFVMQNVLPTDVTMEMVEYLPGDLKDRRSPLGELNWIFTSITDTIAWTTFSRQQFLGLFRHDLMIAALFRNFLLAERVMKQYQCTPTSYPLLPPTNHHPMWETWDLAVEGCLAQIPSLMNGIIRPPSPADFDPMMSPEPLNRHQELPENATYHYVNSPFFAEHLTAFEVWLQRGGSNAPSWDERASIANPHPRRPPEELPILLQVLLAQAHRLRALVLLSQFVDLGPWAVEYSLVIGVYPYAQRLLQSPSNELKPVLVFIWARIIAVEPSCQADLVKDGLYYFAQILNPDEDDRYVDDKASVIPNGPEHRAMCAFICAMVARNYPQGQEACLRETVVDSCFARLDEEDYLTKQWCLLCIAAIWECNDNAKAYAVTEDTIRKVVDLRYDDSAEVRAAAVFTMGVFLGCTMDESGRLLVEPGIPSLGREGKYAEKVAGGGSGAAIPMAEKEQRIMEISLAIEMLLAAKEDASPLVRKEATIMISAVIKEWRGWAVLAAWVYFEEDRAWRLGQVDSKGDSPIRQALDEWLNGEEMDYDEDPDMPEEKEALLRNFSLIVATLFEFSVDDNKCVSEPASKVIDYIICLLFRSPFCSLPFSTFNMPLLPIPEHASKISKVPPIQVPTRGSRISALVGSDGSSIHGLSLSRLSPNEPLPEHPEEDNGIVSNTLRRTASIASTLRSLYTMSRKKEPQPQTNGKSNHDRVATAPNTPPPKTVKPRPSSFYFPQSPGGSPPSSGASPSSTPSPNENHPRSRNVVAIISSVVQDDMERLRHRRRQQEPYSPGASSRSHSPASSDRYTDDDSASFASQIRLSPNDELKHKMPLSSPFFDWSMEYYREPQMKRPENEEPGSVQYNDQMHRKLRNEQMIIKAVHEAEDAGDHPWDRSISYLNNQAAPLNLKFHQFETHMGMTNEADIIHIWDWQNRKRLTRFSNGNPKGTGITSLHFINEDVIGMVLTTSSDGVARIHRDYHEQNSVSLISAFRAVPDIIPSPHGSGIISEWQQTYGTLIAGGDSNFVRVWNCGKEVMISNIPTSEASCVTSLSLDYESGTQFVAGFGDGTMAVFDFRLRPEDAAVASFARHRSWLQKVQWNRRASREILSASVDGEVRLWDLRAPDWSVADWRLHRQGLSSFAMHDNAPVFASLSQVAPAAFRTQTLQVQALSGTHATTLSRLAVPTNLYQPPVSTSLSPFIPFTGSVTFHRNEMMYAVGGVDGTIRLLGLNSPMREKVEWYDEGEFPPYVDWNTIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8P0</accession>
    <name>M5G8P0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Yos1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_19674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the YOS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633475.1">
        <property type="nucleotide sequence ID" value="XM_040771614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8P0"/>
    <dbReference type="STRING" id="1858805.M5G8P0"/>
    <dbReference type="GeneID" id="63686676"/>
    <dbReference type="HOGENOM" id="CLU_152125_0_1_1"/>
    <dbReference type="OMA" id="VQTVMRM"/>
    <dbReference type="OrthoDB" id="15356at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858:SF0">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067634" evidence="9">
        <location>
            <begin position="19"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="94" mass="10048" checksum="738EF0BDB69EAC45" modified="2013-05-29" version="1">MAFSLGTILYVTLLLVNAIAVLNEERFLARIGLSTQTSNPSTYNPSFDQSYGGGPSGPSVRDQLVNLIGAVRTLLRLPLIAANVVVIVYELLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G955</accession>
    <name>M5G955_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_92660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632173.1">
        <property type="nucleotide sequence ID" value="XM_040777097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G955"/>
    <dbReference type="GeneID" id="63692159"/>
    <dbReference type="HOGENOM" id="CLU_1896144_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="134" mass="14864" checksum="778968EB16661A14" modified="2013-05-29" version="1">MKTSRKKRRNQSQQKICESSTLDARVLLTDLSRDRHIMSANATPLPAMPVSNVPPGKSIILGATGHLEKVQNVLKKDDIPILNSTLVRCGLSLGRLRPGWHDWRNPIISWHYESGAQLLSLSLDCAWEGVSIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G975</accession>
    <name>M5G975_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UROD/MetE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632208.1">
        <property type="nucleotide sequence ID" value="XM_040777509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G975"/>
    <dbReference type="STRING" id="1858805.M5G975"/>
    <dbReference type="GeneID" id="63692571"/>
    <dbReference type="HOGENOM" id="CLU_058877_0_0_1"/>
    <dbReference type="OMA" id="HFRYMNG"/>
    <dbReference type="OrthoDB" id="7772923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="175"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="43928" checksum="C30636448E4B2724" modified="2013-05-29" version="1">MAPPPPFRAEHIGSLKRPRHLIDARTKFDKGEVTREKLTKLEDEEVLRVVKLQQKLGFKAITDGEFRRHMFYDGFFDNLEGFTLFKDPNPDIFMDYVPDVAAFKALGFKGGETYLCTGKIKRTKPCYVPWFLALAKDVAPEEVKNIKIAMAAPEWYHLRHSGEYAYSHEVYANDAEYFADIAQAYREEIDALYEAGCRNIQIDDPLLAYFCAVSMLEGLKAVGDDPDKLLDSYIKLYNDCLATKKPDFSVGLHLCRGNFKDGVHFSEGGYDAIAVKLFNELNADFYYLEYDTPRAGGFAPLKELPKHKQVVLGLISSKLPKLEDKKEVIARIHEAAGYMDDPKLERIGISPQCGFASHIEGNLVTEADVEKKLALVAEIATEVFGTTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9D7</accession>
    <name>M5G9D7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632298.1">
        <property type="nucleotide sequence ID" value="XM_040767836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9D7"/>
    <dbReference type="GeneID" id="63682898"/>
    <dbReference type="HOGENOM" id="CLU_1240099_0_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="25268" checksum="33DD67B89FD3933E" modified="2013-05-29" version="1">MSMDRHTPIVVDLTPFSPLDMHTTFTTSAEWLQQLILVEDVVLERYARSKAEHAQYDLRTGGLHVITRDAVYGRDWSEDLASKDIFTINMVSHEDSGFDGMTCLSDFKIARRWSSTDIPDFRNETPGLPGRRKRGQSVTAPRIDVIICRGTRTSEHENGAYQAQDKSQPGEHWKNQKVHEIPHDNMLLVFPGLMFSVFLPHLDHTIVATALPTIVSELGRADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9J2</accession>
    <name>M5G9J2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_74687</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632358.1">
        <property type="nucleotide sequence ID" value="XM_040776080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9J2"/>
    <dbReference type="GeneID" id="63691142"/>
    <dbReference type="HOGENOM" id="CLU_044894_0_1_1"/>
    <dbReference type="OMA" id="IHAVLIK"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="16"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="328" mass="35818" checksum="9EC99C30156E2B2C" modified="2013-05-29" version="1">MVIISTEATKVTGVVSFYMAAALVMVFVNKATLNANPDLPLLFIFNQLILAVIFLHISALFTKHIDLPRLSLRTAKDLFAVVFVNIVGLAFNTLCLRDVEASFFQIARGMVLPLTIAASSIQTRSRPSALVLLAAGCVTIGFLLGIVPSRTLPVHAIPSGLSLLYGFLSALFIAVHAVLIKSSLPHVNNSAIQLAYWTNLGSAIMLLPVIVFDGEASRLFELVTSQIQPWDWRPFLWGSLVTGVFGYLLCVAGLLSIKVTSPITHMFSSAVRSVLQVLLGIWIFGDILTVNRLLSIGTILLGTMYYTWIKSQEMAKPRQDKEPTDEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9J3</accession>
    <name>M5G9J3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TauD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_47715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631824.1">
        <property type="nucleotide sequence ID" value="XM_040774778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9J3"/>
    <dbReference type="STRING" id="1858805.M5G9J3"/>
    <dbReference type="GeneID" id="63689840"/>
    <dbReference type="HOGENOM" id="CLU_036005_0_1_1"/>
    <dbReference type="OMA" id="DGWHTDV"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF31">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="56"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="367" mass="41289" checksum="78A89F60151CD1CB" modified="2013-05-29" version="1">MTKRTFDKEAYKYQEYLPTFPVGVHYDEPVEFKHVDHGLDADPEMPDLLGAASLVDDITPAVGTRLEGVDLAKLTDKQKDQLALLVAQRGVLVFPDQEISIEGLLSLTGYFGPLHLHAVTAMPPDPKLNAVHVVFSDGTKAPDPNWLKKPTWHSDQTYELNPPGVTALKLITAPPSGSDTIWSSGYAIFSSFSPQFQRYLETLTALHSSGDQIQEHMAMGFQARRRRTDTLHPLVRVHPVTGWKTIFVNPTYTKRIVGIPKVESDAVLGFIYKQVEVQQECQVRVRWKDNQVVVWDNRCLLHTALFDSFPHVRHGLRATSQAERPVSVEAYEKEEKKAKDWWTEKLRALGEEVDEDPKNLSKAGGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9U3</accession>
    <name>M5G9U3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631964.1">
        <property type="nucleotide sequence ID" value="XM_040769806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9U3"/>
    <dbReference type="GeneID" id="63684868"/>
    <dbReference type="HOGENOM" id="CLU_035509_5_0_1"/>
    <dbReference type="OrthoDB" id="2686513at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="336" mass="37886" checksum="259571A8AD3EB41F" modified="2013-05-29" version="1">MDTQTPPAAQADLTALETTVFYARVNQYAILAAYCLAVYDILLTIADEAHLISKAPRSIVKYLYFFNGYAMALAFTPLVYIMCGMSSSFSNEVCLHFFAFLLVFDNIQGNGIVGALVLSRVYVLYKNMRYIRYIVLALWLIYLIPVLVSTCHALASYYTLPGNLVWVPSLHTCALYGRPAYLWLIWPFLILVESIVCTMITYKTWKYVRSGVRTPLLSAILRDGWMYYIAMLLGEIANLISFSVAPDPLYFFAVFPFWAISTVVTSTIYLNLRNVTTPTEWDAATTAINRSEESSSDRVSTPTRSLTRRGGSPRLPRSSYSQSDDETFGIELGEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9W5</accession>
    <name>M5G9W5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_62172</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632503.1">
        <property type="nucleotide sequence ID" value="XM_040775691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9W5"/>
    <dbReference type="STRING" id="1858805.M5G9W5"/>
    <dbReference type="GeneID" id="63690753"/>
    <dbReference type="HOGENOM" id="CLU_022389_2_1_1"/>
    <dbReference type="OMA" id="IRHFGVK"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="535" mass="58729" checksum="26655D1E049011C0" modified="2013-05-29" version="1">MCGILGLLLHSPDAQAAPEIYESLSLLQHRGQDAAGIVTCGTKGRFYQCKANGMVRDVFDAQKISHLFGSMGVGHVRYPTAGSSAHAEAQPFYVNSPYGIVMGHNGNLINTSELRFFMDHEAHRHINTDSDSELLLNIFANNLQKTGKFRINEEDIFAAIRALMTVCRGAYACVAMLAGFGIIGFRDPNGIRPAGMASRPGAQGGTDYILASESVVADASGFGDWTDIAPGEAVIITRQRVSRRILAPGKSFAPDIFEYVYFARPDSVLDGISVYRSRMAMGELLSYEVERQLKEKGIQVDVVIPVPDTSRVAALELAQRLKLPYREGFVKNRYVGRTFIMPGQQMRRKNVRRKLNAMALEFVGKNVLLVDDSIVRGTTSKEIVQMAKDVGAAKIVFASCAPPIRYSNVYGIDMPSRSELVAYQRSNEDIAREIGVDLVIYQTMDDLVKACRMINPKIEEFDCSVFTGEYVTGGVDDAYLAGLEKLRNDNAKLKEGKMTNGAVNGESREDPTGCSGPMNGADDTIGLYNSFYARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA51</accession>
    <name>M5GA51_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_75009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632578.1">
        <property type="nucleotide sequence ID" value="XM_040776101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA51"/>
    <dbReference type="GeneID" id="63691163"/>
    <dbReference type="HOGENOM" id="CLU_100697_0_0_1"/>
    <dbReference type="OMA" id="INITHTP"/>
    <dbReference type="OrthoDB" id="2497589at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="182" mass="19096" checksum="877515733B335D85" modified="2013-05-29" version="1">MSPRAEKRSAPASSDRQTRSSKVAKTDSKDVATAQSNNKSKKGKKVRPMPSSAFKSAALPLHIHITHTPPTIDVPSSAEPSAQDVGHIASITMLPCDFGTGSYGWKGQKRTVVQLMGGEGDGKEKVQVMFSINAVVVGSKDAEADIIDEPPAEVEEAEADVEKDDAADAKAEKAVKDAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAX3</accession>
    <name>M5GAX3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627985.1">
        <property type="nucleotide sequence ID" value="XM_040768647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAX3"/>
    <dbReference type="GeneID" id="63683709"/>
    <dbReference type="HOGENOM" id="CLU_415615_0_0_1"/>
    <dbReference type="OrthoDB" id="3149711at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="660" mass="75411" checksum="A5EE232A0ADE2179" modified="2013-05-29" version="1">MDSAHQQKRIRFSQPRPKPAPIVPLKAEVTVASVMIAAKSLSSLDIDPLLSLSPVQTSMWKRLRKTVNTVIRERKAAGIPLGPIPTDAEIDYKALRLIIRQSMSRRSLGVVALEKYLRERLRILRQERVKQMLEEAQTKVKEQAGIMGPAVPVSPLDAASMEPPASGPSMPSTPTRSRVGIGTSYKWKRFFRLFGRGRQLHTLSRALEDDRVARFSPRTNKFRKSVHSVTSRRRTAFTIAFGSPQHKAVQFPPSSLFNRPSTCQAAFRQLLEFSKPYRRPSVKAVVEFHRSLGAVRSTTSFNYVISVCIRERFFSEAQKSFFEMRSCHIPWDSATWVEFVRLNVATKKWDTIETILASQVADFDTMLTLLPGQVIHRPRNPVATTKDTEEKLRLLSNANVLVTHEQALCLPYPARYKIIRSLLVTNPDAALEMTKSSIRKLPTAPSQVQLGQALGLIHLHLRAPSKPSGVVQYWDAWKRLESLLELNQNIRPTPFTIYLLLKYIRGVRNRNRMARKAVSAYKKRWGESVEDYWTLLVQARYAMHDKDDNGAFDLLQKALKLLQEHERRGVAGNPATSRFVMKRYNHGWSRFYDLMRRWKFRRERMKMRADNGDKGKKNAVESQALEEVPSVVSVKMSLALPTLEQTSICPTYPVLVRARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB41</accession>
    <name>M5GB41_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phospholipase C/P1 nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_116970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628070.1">
        <property type="nucleotide sequence ID" value="XM_040770292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB41"/>
    <dbReference type="STRING" id="1858805.M5GB41"/>
    <dbReference type="GeneID" id="63685354"/>
    <dbReference type="HOGENOM" id="CLU_044365_2_0_1"/>
    <dbReference type="OMA" id="HQIVATI"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF29">
        <property type="entry name" value="S1_P1 NUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067625" evidence="8">
        <location>
            <begin position="24"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU01173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="365" mass="40878" checksum="621900DBE752C25A" modified="2013-05-29" version="1">MRIYASSLISSLLCALQVTRVLAWGVAGHQIVATIAQIHLLPSVQEQLCDILPYNARCHLAPYAAWADSIKRKPEWRWTSSLHYVNGIGDHPAEHCVFGDQGWTSEKNLLSALVNVTYETKNYGAERQDTAVRFLTHYLGDLHMPMHLSGRDRGGNGDHVKFEGRSTNLHTVWDTLLITQSIRTLSNYTRPLPSTRIESALRGSIFDPYVRWIVWEGIRGWWADEYLAWPTCPADGDLDPSLLIPHNLDENSPDFPVHSLANQAIFNVGPKTPIDPVDLPICPLAWATTLHPLNCQYVWPPHYDTHGKPPELDTPKYLGPIRDQHVVEHVLAMAGVRLAAVLNTLLGGEDEKRALGHGLDALAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBB5</accession>
    <name>M5GBB5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_92318</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633118.1">
        <property type="nucleotide sequence ID" value="XM_040777058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBB5"/>
    <dbReference type="STRING" id="1858805.M5GBB5"/>
    <dbReference type="GeneID" id="63692120"/>
    <dbReference type="HOGENOM" id="CLU_081646_3_0_1"/>
    <dbReference type="OMA" id="AAYKEIY"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21693">
        <property type="entry name" value="GINS_B_Psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055221">
        <property type="entry name" value="PSF3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22466">
        <property type="entry name" value="PSF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="73"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="21306" checksum="29C1A76CADE2D698" modified="2013-05-29" version="1">MDNDYWSFESCLSEQQKIPCTLKLEVGNHGNLLGASESDLHVGGKVSIPMWLAPTLILNDWLDFNIPPPFMQRVKRALNADARSVRLSALVGNGGEWYGFGKLVADILEESQAKELQGVLLTTFKERFVDLMDQAQHFGSLPGSAADNMGDRGSDFREGLEMTERELFLLGQESAKAVRLWYESTDRKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBD9</accession>
    <name>M5GBD9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630261.1">
        <property type="nucleotide sequence ID" value="XM_040772446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBD9"/>
    <dbReference type="STRING" id="1858805.M5GBD9"/>
    <dbReference type="GeneID" id="63687508"/>
    <dbReference type="HOGENOM" id="CLU_008455_11_5_1"/>
    <dbReference type="OMA" id="PMMLSCW"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF48">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="144"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="614" mass="68112" checksum="8A8E4B86E4F3EDB5" modified="2013-05-29" version="1">MSSSTSHPHTLTPSCSLPASAARRLSFHSDAPTLAHPHPVRHQTVMLGEHRVGERRLSMHHPKPEPLPRSVSPDDVLSAPIRTVASSAALQALAEFTKETPGGEILRTIPSHVSGQLRTVELVTFKTDDPENPKNWSKAFKWWCTMVVAFTCFAVAFASSVITADLQGPADEFGVSYEVSLLSITVFVIGFGVGPLVFAPLSEMYGRRPVYVFTLALAVIFTIPGAVAKNIQTLLVTRAIDGIAFSAPMTLVGGTLADLWKNEERGVPMAAFSAAPFLGPAIGPLVGGFLSDHRGWRWLYWIQLILAAVAWLLLTFTVPETYAASLLYQRAKKLRKETGDDRFVTEQMIDPRPTGERLRLFLLRPFQLLFLEPIVFFLSIYMSVLYGLLYMFFVAYPVVYQEGKGYSASITGLMFIPLAIGVVASAVCSPIINKHYLHLVKKHFGRPPPEVRLIPMMIFCWLIPVGLFIFAWTSYPRLHWIGPAIGGFPVGFGFIFLYNACNNYLVDSYQRQAASALAAKTFIRSIWGACAVLFTIQMYHRLGYQWASSLLGFIGLACCAIPYVFYFKGAAIRKYSSFATYDDDDDTATLAEREQIQEAISPTQEKPKKPIMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBF6</accession>
    <name>M5GBF6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632609.1">
        <property type="nucleotide sequence ID" value="XM_040771798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBF6"/>
    <dbReference type="GeneID" id="63686860"/>
    <dbReference type="HOGENOM" id="CLU_1147163_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="26280" checksum="3BB05AD0915FBE6F" modified="2013-05-29" version="1">MEDSEKDRHRTSIEPRSIESAEKWVADALDRGVDVELILAVLEKHKGSTSSSTQPRLTNAMAKRPASALDESGDRVVPSTSEVRMPVYDRAQKRRRPGGSLSAKSGARTDMVVSPDANSPSPRENTLIAAEPASAHVDDRIASLCISDYDAAMQRTLNDAKSEMRLHMYKSTPFPLDKAAIADMIKSAVRKANELAITRGGPTMELAGNASCGIYKLVAGCFRSGLWPDQDEGKKISQDPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBQ7</accession>
    <name>M5GBQ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19580</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633313.1">
        <property type="nucleotide sequence ID" value="XM_040771572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBQ7"/>
    <dbReference type="STRING" id="1858805.M5GBQ7"/>
    <dbReference type="GeneID" id="63686634"/>
    <dbReference type="HOGENOM" id="CLU_013253_3_4_1"/>
    <dbReference type="OMA" id="KYDHDAS"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05488">
        <property type="entry name" value="Proteinase_A_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000036">
        <property type="entry name" value="Vacuolar aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000002">
        <property type="entry name" value="Vacuolar aspartic proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033819">
        <property type="entry name" value="Saccharopepsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067639" evidence="13">
        <location>
            <begin position="20"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="102"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="336"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU06419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="413" mass="45065" checksum="6FB51160E5471528" modified="2013-05-29" version="1">MHLSTLLPFLSLLAIPTDAKVHRMKINKMARTAASFQQDPSLESAYLAEKYMSRVQLPMGYGGPAGKVSEGVHRDKDLYWTQDTTIQGSHGVPLTDFMNAQYFAEITLGTPPQTFKVVLDTGSSNLWVPSIKCTSIACFLHQKYDSAASSTYKSNGTAFEIHYGSGSMEGFVSNDLLTIGDLQVQKLDFAEATKEPGLAFALGRFDGILGLAYDTISVLHMTPVFYQMINQKLLENPVFAFRLGNSDADGGEATFGGIDESAYTGKIDYVPVRRKGYWEIELDKISLGGEDLELESTGAAIDTGTSLIALPSDIAEMLNKEIGATKSWNNQYTVECSTVDSLPELTFYFNGKPYPLSGRDYILEAQGTCISSFTGLDIPPPLGPIWIVGDVFLRKYYSVYDLGRNAVGLASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCB0</accession>
    <name>M5GCB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ArfGap-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_108197</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628565.1">
        <property type="nucleotide sequence ID" value="XM_040768607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCB0"/>
    <dbReference type="STRING" id="1858805.M5GCB0"/>
    <dbReference type="GeneID" id="63683669"/>
    <dbReference type="HOGENOM" id="CLU_027009_1_0_1"/>
    <dbReference type="OMA" id="CFDCGMR"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000026">
        <property type="entry name" value="GTPase activating protein for Arf, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="3">
        <location>
            <begin position="13"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="53709" checksum="FE093094DD01A91A" modified="2013-05-29" version="1">MSGLSKVQAERNQRVVIELAQQPGNDVCADCKARLPRWASWNLGIFLCVQCASVHRKIGTHITKVKSLTLDSWTREQVDSMKNMGNIKSNAYYNPDERRNPPPTNMEDTERDSELEKFIRAKYEYKKFLAHPGSAAAQAEKKANGLLPPPPPKDQVPRSKTAPPPQALANKPSPPPVPANESPARMPSFAQQPPSTQFQPQPPPPQLGMRPMSSAPAFPQQPRIQLPPQMPPRPSAQPPTPSVLPPSSPVYGDMMALQTGGPLPPSVNPMVGQSMSMPPMGAAPNPFQALQQSGTPTYPSAFNTLGRSPSRSVSLPVGAPTLAMQATGINPFFAQQQQRQSMQQGALLQGTPTTGYLPTPPAMPSSFALPSANVPPINIPPVQPQATGYFPSPQSTGYLPPSPSAGFLGPQPSTSPFSAAYGSSAPSTSPFPQAYPQSSPSPFGNIQQPAFTGTPTGYGAPPTPFSQVGGGSPFPQPQQAQPQQGNLGAFASGMMPRNSTNPFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD85</accession>
    <name>M5GD85_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_76757</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631236.1">
        <property type="nucleotide sequence ID" value="XM_040776225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD85"/>
    <dbReference type="GeneID" id="63691287"/>
    <dbReference type="HOGENOM" id="CLU_003181_2_2_1"/>
    <dbReference type="OMA" id="MFLKINM"/>
    <dbReference type="OrthoDB" id="44789at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000011">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF9">
        <property type="entry name" value="ANION_PROTON EXCHANGE TRANSPORTER GEF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="594"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="720"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU04342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="820" mass="91858" checksum="3C292F670B00090D" modified="2013-05-29" version="1">MAHHTRLNSYDSPVLRAAENGYPPENLVSHEDEEEELEQIRRYEDFRTIDWIHDSMLERNRRMRQKKAMRHPFRNPDGSFSWDWLRYQLRWAGRMGQDSFIVTAVGAVIGITSALISILTEWLSDLKMGYCSDGWWLNQQFCCWEIDNIEGGRCRAWRVWTPSSALSYLIYVIVAALFSFLAAHLVKSYAKYAAGSGISEIKCILSGFVIKGYLGIWTFVIKALTLPLVIASGLSVGKEGPSVHIAGCVGNIIARCFPSFRRSESKMREILTAASATGVAVAFGSPIGGVMFSIEEMSHIFTIKTMWKSFFCALVATVTLSFMNPYRTGKLVLFQVRYDRDWHFFEIFFFVIIGIFGGLYGAFVTKFNLQVAAFRRKHLASYPVAEAVILATVTAVFGYFNRFLRIDMNESLAILFKECSGGGDYENLCQTWAQWPMANSLFIATIFRIGFVIVSYGAKVPAGIFVPSMAIGATFGRMVGIIVKAMYQAYPTSGWFAACQPDAPCITPGTYALLGAAAALGGIMRLTVTVVVIMFELTGAATYILPLMIVLLVTRAVGDLCGASGIADEMIRFNGFPFLEKEEQSYDVTVSSVMHRELVTLSATMRLGDIKHILETTTVQGFPVLNSHSKVLRGYIGRTELLFVISKARRAGNPSPNTLCELATEEHIHETGQPELPLITPTPLDGHLGPMGIEEDEAAPEAIEDLSILPNERLNFKPWVNKTPLTVAPQLPLEIVMQLFKRMGPRVILVERYGSLVGLITIKDVLRYTAETEHAQSLSNRYDEWSSLDSTLVEAYSWWKDTQHDALDRMRQWARVVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDE9</accession>
    <name>M5GDE9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629222.1">
        <property type="nucleotide sequence ID" value="XM_040768436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDE9"/>
    <dbReference type="GeneID" id="63683498"/>
    <dbReference type="HOGENOM" id="CLU_138920_0_0_1"/>
    <dbReference type="OrthoDB" id="5946233at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11877" checksum="BE305FA1158FCE68" modified="2013-05-29" version="1">MQSKLDEYCFMHNTSKPCKDRKKLLPTAIPELALHHPKRYGALSFKVSVSEDELQEVEQLYAPPEHEVFKLVPTFFKWAIESCYFDMGSPTIMLQTFWTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK2</accession>
    <name>M5GDK2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629372.1">
        <property type="nucleotide sequence ID" value="XM_040772682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK2"/>
    <dbReference type="GeneID" id="63687744"/>
    <dbReference type="HOGENOM" id="CLU_2542528_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="10392" checksum="A9DDA7DD2C67B183" modified="2013-05-29" version="1">MLWWWTGGFRLDRWWSLRKYELFIRFSPTLGVRDESQDSKELPRCDRIIQRRFRIPYRQYLFHDVVLYRVGPGEVPSNRHRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK9</accession>
    <name>M5GDK9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_79319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629392.1">
        <property type="nucleotide sequence ID" value="XM_040776393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK9"/>
    <dbReference type="STRING" id="1858805.M5GDK9"/>
    <dbReference type="GeneID" id="63691455"/>
    <dbReference type="HOGENOM" id="CLU_014831_4_0_1"/>
    <dbReference type="OMA" id="WSKNTDE"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="223"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="275"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="350"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="551" mass="60182" checksum="D6FEA9BEFD48EE22" modified="2013-05-29" version="1">MPNPDFVRRIRTATANGSSGEPSPTGNPRSGSSTASANPFASLLEAGPSSSSGSSVGSYGSPNRTYVPGGTPTSSPRKRKARDYGDRFIPNRDDNLQTAFQLIGDSPTTRSRKRSSNPPATDGNREQANLAFQSLLATELFPSGPSSPPRGSTTPAGTPSTPSRKRIFQYSSPSRSRLNRDLGLSNPVHQAYSISPVKFESQRLLLSPQKTVRKVAKTPFKVLDAPDLIDDYYLNLVDWSSTNILGVGLGTSVYVWTQETGAERLFELAPGDSATSVNWCQRGSTLAVGTQMGTIQIWDAEAQKQIRTMYGHDNRIGCLAWTGHLLSSGSKDRTIYHRDTRAKNDIVKRLTTHRQEICGLKWSDDSGGLAGCQLASGGNDNKLFVWDGKMMDQPMWKFHEHTAAVKAIDWNPHSRGVLASGGGTQDKKIRFWNTVAGTMLGEVDTGSQVCNLVWSKNTPELVSTHGYSTAPGQNQIIIWRYPSMSTVTQLTGHNQRVLYLALSPDGTTIVTGAGDETLRFWNVFPKREEREEDKAVGEELGPSLELFNKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE91</accession>
    <name>M5GE91_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
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        <property type="entry name" value="Zip"/>
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    </dbReference>
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    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="297" mass="31081" checksum="2CF28F366C79CA12" modified="2013-05-29" version="1">MGFTALFLMSAVMGVTSFAVGSLPLTLTFSHSRLKMLTTYGMGLLLGAALAVIIPEGIETLYSSLPAAGERTDSNPFSQPGRVVAVSLVLGFSVMLFVEQLSSHSKNSGSSTYEMASPGGTLHQHAHESHSKAFSATLALVIHSFADGIALGSSSLGDNSGLELVVFLAIMVHKAPASLGLCTTLLSYSEPRPRIKQYLFAFSAAAPIGALVTYGVVWGLGNAAANLQWWAGVALLFSGGTFLYVATVIQDVSGHSHAPEVEEATPTEELSVSTRLTLLVTGMLTPLVMSTLVGHKH</sequence>
</entry>
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    <name>M5GED2_DACPD</name>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="1858805.M5GED2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
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    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="24"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="39231" checksum="AF9B80518E472F3D" modified="2013-05-29" version="1">MSNQLPQVEYRRLGNSGLRVSVPILGAMSFGSDKWAPWVINEDKALPLLKAAWDRGITTWDTANVYSNGESERIIAKAIKKYNIPRSKLIILTKANGLVHEDPGVRTMMFPKLRDTRDYLNMSGLSRQALFQQVEASLERLEVDYIDLLQIHRCDMNTPFEETMCALNDLVRSGKVRYIGASSMWAWQFAEYQHAAEKNGWTKFISMQNHYSLLYREEEREMNKYCNHTGVGLIPWSPLAAGQLARPLGETSVREDTAKGTPFEMKKSDADKEIVNRVEKLAKQKGWAMGQVAQAWINTKVSSPIIGFSSAARMEEAIIPDKKLTEEEIKYLEEPYAPKPIQGHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEH4</accession>
    <name>M5GEH4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103912</name>
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    <organism evidence="2 3">
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632321.1">
        <property type="nucleotide sequence ID" value="XM_040767839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEH4"/>
    <dbReference type="GeneID" id="63682901"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_3_1"/>
    <dbReference type="OMA" id="IMIHIAY"/>
    <dbReference type="OrthoDB" id="3354175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="330" mass="36333" checksum="F777C3209D686255" modified="2013-05-29" version="1">MGIPVDRATLAGLFASSVLYGMFLMLLASCLYVLLCRRNTLNPNYLLILAACLMLVVNTFILAFSFSRVLDAFIYLKGNTTSPDEYLTMLSQWKEVARTSACSFYIFVADLTLIYRCWIVWSRSFAIVFFPIMIHIAYMVTSIFLNVNLAHLPQGATIFDPAVKSWIAAALAISSGQNVIVTSLIAFKILSVNIRATGKRLGTLSKTVQIIVESGLTYVITVLVYLITYTANSNAQYVMIDILNPIIGITFSLLVVRVAMRRGPESSSTDEIAPSSRPEVLRLPQSVVVTVQQSEVVEGLDSTSDLDVTKYGTTSGLPLRDVELEHDVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ8</accession>
    <name>M5GEQ8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pkinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_74898</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632506.1">
        <property type="nucleotide sequence ID" value="XM_040776094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ8"/>
    <dbReference type="STRING" id="1858805.M5GEQ8"/>
    <dbReference type="GeneID" id="63691156"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="DAQQCIF"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000334">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="81"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38201" checksum="2366E7480705FAA1" modified="2013-05-29" version="1">MAEQGEDGQYVVVASAKPVGGLSPAYEDEAEELPEEPLVEEDEDDLDEGDEEDAPENEADAEGDEPGKPQTSNGGKRSIRWLKGALIGAGSFGSVYLGMDSSTGTLMAVKQVELPTGSSSNEERKKNMLSALEREIELLKTLQHENIVQYIDSSSDEKFLNIFLEYVPGGSVAALLTSYGAFEEPLVGNFVGQILTGLNYLHERDIIHRDIKGANILVDNKGGVKISDFGISKKVQGDFGGGRAAHRPSLQGSVFWMAPEVAMQKAGAYTRKADIWSIGCLVLEMLTGQRPWAELDQMQAMWKIGSKVKPKFPSDISANALDFLNKTLDPDPDKRPSAEELLQHPFILASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEZ2</accession>
    <name>M5GEZ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_49849</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630577.1">
        <property type="nucleotide sequence ID" value="XM_040774945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEZ2"/>
    <dbReference type="STRING" id="1858805.M5GEZ2"/>
    <dbReference type="GeneID" id="63690007"/>
    <dbReference type="HOGENOM" id="CLU_002833_1_0_1"/>
    <dbReference type="OMA" id="QTQNHIN"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000075">
        <property type="entry name" value="Sporulation-specific chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="379" mass="41576" checksum="2DB30D9A2B06D79D" modified="2013-05-29" version="1" fragment="single">YYGNWDIYGRGYMPSDVPASDITHLLYGFADVNPSTGEVILSDAYADQQKHYPGDSWNDVGNNLYGSFKQFYLIKKQNRNFKVILSIGGWTYSQAGHFDPVIVSPSLRAKFVSSAVSLLEDNGLDGIDIDYEYPDTDAKASGFTALLSELRAALDAHQQSKGDTVPYSLSAAVSAGPQNYAKLQVKEMDPLLDLWNLMAYDYAGPWSSESGNDANLYGGDINTDSAIKWYLSQGATSTKVNMGIPIYGRSFENTDGLNQPYNGVGQGRWEAGVWDYKNLPLPGAQVVEDLQTVSSYSYNPQTKELVSYDTPTIVQAKAKYMLQHNLAGAMFWEISADATGQRSLVGTTAGVFGKLQQIQNHLDYPGSQFANLKAGMPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEZ5</accession>
    <name>M5GEZ5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TFP11-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_93970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFP11/STIP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630582.1">
        <property type="nucleotide sequence ID" value="XM_040777189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEZ5"/>
    <dbReference type="STRING" id="1858805.M5GEZ5"/>
    <dbReference type="GeneID" id="63692251"/>
    <dbReference type="HOGENOM" id="CLU_007977_2_1_1"/>
    <dbReference type="OMA" id="RALQKWH"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="269"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="317"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="842"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="842"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="951" mass="106574" checksum="CD20E0582C54AA38" modified="2013-05-29" version="1">MARRKRQILSDDDSSDDSREEDGDDFNPGENNDERAERELFQNPYARNKKRKRRDLDNEDDEDEGFGGCQPAARKRSDWTKAPNFVSGGIKTVTLDEAEGIDSSDEVTGEPGPQHEDDVDHDEELDEEAEEIPPGDEEESDQDMDVSDEDQPVAEPRIREPEEDEEANPARSGFSAARSMMSSFSTTAGTSAAPSSTAGIGARGGIGAGRGGITSSAASYGLPAAFGASTPPVERSKPSFVRSAPVTAPGTPTPPNLTTAERRHFDSLSNTIGAKLMAKMGWQAGQGLGAEGKGIVNPIETKMRPTKSGIAYRGFKEKTEQSKAEARRRGEHVSDEEDQRPAMGGMQRGERAEVLRKTMKKGKVKVEHKTYEELIREAGADESAMLPDLGIIIDATGPEMREVSLSEASAFWAPTADQTPPPQVDETKLALQGLAREGRALNEREKYLAGEGKRLGSMVRQEAEMIARLERMRLLVDQLNEEAKEITATYEPSLDPFTKSFETILNEFSTESDKFGVEEVFVGAMSPVIRRMVTNWEPLLHPEAISQPFYQWRRAFLLRPFQPPNERFSNKGQSDENALQMTPYESLVWTVWLPKVRMSINNSWDPIDPDPAIHLYKTWAPLLPDFIQANILDQLLLPKLSKVVADWDWRKSVPLHSFVFPWLEYLDLRSEQLLEDCKRKIKSVLKTWNVNDGLWKQITAWRDVFAPGDWDNMLLKLIVPKLSAIMREDFKVNPRDQKMEPLNRVLEWKDVIRPSVMGQLLEKELFPKWLNVLHFWLVQPKTSFEDVAQWYSFWKGYLPTSVSKLEPVEQGFNRGLHLMNLAIELGPSVAKELPRPETLATKNASRTGVSTTRPQNGTPKHAAAPLAAEVTFRSIVEDFVAAHNLLFIPIGQVHEVSRMPLYRVSPSIDGKGGITAYLLDDAVWMQEGADWKAVSLEEMVLRANRAGARQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFR5</accession>
    <name>M5GFR5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_48852</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631252.1">
        <property type="nucleotide sequence ID" value="XM_040774869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFR5"/>
    <dbReference type="STRING" id="1858805.M5GFR5"/>
    <dbReference type="GeneID" id="63689931"/>
    <dbReference type="HOGENOM" id="CLU_011856_6_2_1"/>
    <dbReference type="OMA" id="SWATDAH"/>
    <dbReference type="OrthoDB" id="2161780at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF165">
        <property type="entry name" value="DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="51651" checksum="2301C73CCB1B02C6" modified="2013-05-29" version="1">MDAHIRAHVDALPNLPPIADPAKLRTALESLPTSLPEHGWGDSRTLEYLTGSIAGGLAQGQAGPRYWGFVTGGVLPIAQAADNLVTLYDQNVQVHLPSQSISTVIESRTLELLLSLLSLNPTNFPGRTFTTGATASNILGLACGRQWAIAKAHPGYDVAEDGFGGFGCKVLVAKTHASLIKAASLVGIGRKNVIECGVKVDQDGGLPFDLQKMELLMQECKQRGDGIIVSPGFGEVNTGGFTPEIPKIRALCDKYGAWMHIDGAFGAFAKLVPDLQSYVEHLDLADSITVDAHKWLNVPYDSAAFFTRHVNVLPSVFGPSPSTGGPAYLAAGSAGATYPALDAVLSIPSPLNVNIENSRRFRALPVFAALLSLGREGYAELIQRNVGFARVLGKYISTHGSYELLNPGNQVALNIVLFRAKNLDSGELLRRINASGKIYASPTSWAGQGAVRIAVSNWMTKMEAIGDGKSDLDTAIEVLDAAVKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFR7</accession>
    <name>M5GFR7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">General stress protein FMN-binding split barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631257.1">
        <property type="nucleotide sequence ID" value="XM_040772142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFR7"/>
    <dbReference type="STRING" id="1858805.M5GFR7"/>
    <dbReference type="GeneID" id="63687204"/>
    <dbReference type="HOGENOM" id="CLU_091428_0_1_1"/>
    <dbReference type="OMA" id="GLDILFH"/>
    <dbReference type="OrthoDB" id="434253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052917">
        <property type="entry name" value="Stress-Dev_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34818">
        <property type="entry name" value="PROTEIN BLI-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34818:SF1">
        <property type="entry name" value="PROTEIN BLI-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="General stress protein FMN-binding split barrel" evidence="1">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="19853" checksum="4902E5405FFC42D1" modified="2013-05-29" version="1">MSSENMTVQEKVDGLNEVLKSMKYCMFTTRSPAGELHARCMTLGSTDEHFKFSFIANNVTFRIDEIEFDGHVNLSFFDPSSTCWVSVAGTAQISNDKETIDSLWKPADEAWFGDLGDGVHTGQVSDPRVCAIQVVPDSIRYWISRHAMPGGTAAHGELVTIPGVEMRVIEGMSTSCKCNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG39</accession>
    <name>M5GG39_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_47001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631712.1">
        <property type="nucleotide sequence ID" value="XM_040774734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG39"/>
    <dbReference type="GeneID" id="63689796"/>
    <dbReference type="HOGENOM" id="CLU_007337_2_1_1"/>
    <dbReference type="OMA" id="MDINSEY"/>
    <dbReference type="OrthoDB" id="3257409at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="129" mass="14288" checksum="89B5647085059A5C" modified="2013-05-29" version="1" fragment="single">FVSAIKTVSYDCCVSSCVAYTGVLAEETVCPHYSEPHLKPNGQAHCQYAYLPLIPQLQAQYAQEDRAKLLTLYQGWQNANAPTITNIFQDLCECYIKVSGKTLTTKYFDSPRDLALGLLTDGFAPFKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGR8</accession>
    <name>M5GGR8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_73183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632857.1">
        <property type="nucleotide sequence ID" value="XM_040775996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGR8"/>
    <dbReference type="GeneID" id="63691058"/>
    <dbReference type="HOGENOM" id="CLU_897205_0_0_1"/>
    <dbReference type="OrthoDB" id="3062801at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="32540" checksum="DBA6CB1C9A882BD5" modified="2013-05-29" version="1">MEQIIRCLHSPEWEYDLEAGEPGSQPLKEFKLSWEEFIDHVIKEWKTLNLVSALLLTAILTLFQIEVSNEPVTHTCGLLSLVCALMSLIFGCMYIIRFSTMRPMSKAARWAQAAQASQTNPIWNVWIFLAIPAVFLAWSLIFFIATILAYTWTSDPIVPPEYLTAPSSWISRSFVSAVVGLGVLAFCGVIMTFKSYSDEGTVTPAPFGSPLVNVASPRSSNEQGRAPVAGGVGGTPASASGTITGTGGTGGTGTGNAAGMGTPSRTGFALGEERTLGLGLTGVVRGNGHGPGPGNGNGNSNGGVGVGKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGT3</accession>
    <name>M5GGT3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Longevity assurance proteins LAG1/LAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_19365</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632932.1">
        <property type="nucleotide sequence ID" value="XM_040771475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGT3"/>
    <dbReference type="STRING" id="1858805.M5GGT3"/>
    <dbReference type="GeneID" id="63686537"/>
    <dbReference type="HOGENOM" id="CLU_028277_4_1_1"/>
    <dbReference type="OMA" id="LCRLCML"/>
    <dbReference type="OrthoDB" id="3053196at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="185"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU06038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="431" mass="50948" checksum="574E2390896B06AA" modified="2013-05-29" version="1">MATGSSNHNSSSPKGRRRGSSIVETLHRIEHDPNHHLAGPFVPDKPSVPAHPPQDPTGKIKHAKPKQKVAFAVDVNSRSGGLWEDMRTMRWMRVPASSAKILGVPILLWLNWHFLSSHQPNPFSHVILLSGRVPGSPDDDPRYQKSYWDILFITYYVVFWSFVRQSIVLYILHPLARLAGIRKEGKLDRFAEQGYAIIYFGFSSSAGIYIMRQLPTWWYRTEYFWIDYPHWDMLPAMKAYYLLQFAFWLQQFLVLVLRIEKPRKDFQELVWHHYVTLWLIGWSYLVNLTYIGNAVFVTMDFSDTFLSVSKILNYLKLDRISVISFIWFIGVWTYMRHYLNLRMLYSVWTQFELIAPENREWDPPRGVWLAWWMKYQIFVPIALIQLLNIFWYLLMWRVLYRAVFGTVIGDERSDDEDEPESPIAEKLSKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGX5</accession>
    <name>M5GGX5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SNARE-complex protein Syntaxin-18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_44770</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633142.1">
        <property type="nucleotide sequence ID" value="XM_040774608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGX5"/>
    <dbReference type="STRING" id="1858805.M5GGX5"/>
    <dbReference type="GeneID" id="63689670"/>
    <dbReference type="HOGENOM" id="CLU_038403_0_0_1"/>
    <dbReference type="OMA" id="YRIRTHI"/>
    <dbReference type="OrthoDB" id="342981at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000069">
        <property type="entry name" value="Related to syntaxin 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019529">
        <property type="entry name" value="Syntaxin-18_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10496">
        <property type="entry name" value="Syntaxin-18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="SNARE-complex protein Syntaxin-18 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU06248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="355" mass="39852" checksum="BA74FE94F0048A8F" modified="2013-05-29" version="1">MVAIDITADFRASVGSALKLVPDTKRRHKPRVRNFFEVKAEKNYAQAYLKEAYAILEHINTLDQMLASIRHAYLSVDSSHSHTRRGGFDASQKEGWGEVKRLTNQERDEIELQAKVILKRCAERVKHLEELEEKRASTQPSKHPLARLLPPRLLVTPSTSGHDVLAAHYAGITWYLNRKLASSSGKQREMQEERVRRQLERARSLGSEVAAVGPVQGDVKGEQVRRFDPTLAGRGPSYANGEEDTPLTAAQALLFEQENAAILRSAESVLAQVQRAEASLSEIGALQSELVHHLTMQTEMTDRLFEEAVATQAEVERGNQQLKRAKERGGDARRWLLVFLIGATLALLFLHYYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FND3</accession>
    <name>M5FND3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624143.1">
        <property type="nucleotide sequence ID" value="XM_040770841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FND3"/>
    <dbReference type="GeneID" id="63685903"/>
    <dbReference type="HOGENOM" id="CLU_010086_2_1_1"/>
    <dbReference type="OMA" id="MIYKELH"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="603" mass="67304" checksum="67128D0E1E6BBC6D" modified="2013-05-29" version="1">MSMSSMRSEISTLSSASYSRSDALEDLPYVHHILQLFLSSKMMEAEDLVREGDPKQERLYFSTAWSIIQAIKAMMSFDDKELAEAIEDAKHTTEVAQRHRKPSLGLASRVAGLVVGGTGAAFIRGMTDVERHAELVYAETLLIKAVLGIVSSGDWLAFVKEALHMRSALNIYKHLDQFVQQADKEAFERGEGEAEDIDQDFRSGVLLGMGINSLVLSLLPSKVITIVELFGYKSNRRQALKTLAKPGGWSRSAPSPQSTQSTKASDAASFAEKMLNWNLERFPEGVFYLFMQGRLHVSQSQPRLAIAAYDRAAQIQKEYVQLQHVAYWEQGILMMSMGDVLPAVSCWRKLVSSSSWSKAVYTYALASCLVHHGNPSQIAEAEQLMKLVPTYKQRIAGKSIPIEKFAARKARKFQSQGKRLLLPAFEFALVMQVMGRMTPKILHENVLPLVRKEIQALRSTQPKDWGNGTGYWDDLALARYMEGVVLRYIAYPDPDAVLQESDKVNISQKETAEASLAAFQEVLDNGFKVELDHYIVYYTHYDLGRLHACLGNVPEAKRHLELVMSGKTLEVNASGKKGKYSLENALMVRTHAASEAIDEGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPF3</accession>
    <name>M5FPF3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_25439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623931.1">
        <property type="nucleotide sequence ID" value="XM_040774162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPF3"/>
    <dbReference type="GeneID" id="63689224"/>
    <dbReference type="HOGENOM" id="CLU_831659_0_0_1"/>
    <dbReference type="OMA" id="FLARWPH"/>
    <dbReference type="OrthoDB" id="2523549at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="167"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="39589" checksum="8ADFACED8955D044" modified="2013-05-29" version="1">MTTSPRLVNYPTPSAFLRACLPFDTWHMNISLGPTLQYLADSGDFQPAPGEAKLWLAVWTGEQLDLTLVRTSKLVTLCSPLHSSFLSQAYLEPRMTLLAESLHALITSRSQPPLSTLTGPTTLVQAFVPAYRALSSLQPREPAVIHTLHTHCPSSRVSPAPPLPEGYQIRPVKPGDPRSLEALAHMLLDFRNLYHGPWPALSLVQAREHAEEAVRLGEVLVYVVPSSSGEEGEEFTGFVRDGRLTRRFAAVRNVFTRPSFRRRGVAEALTRAAVLRLLGEPHRLATLVAPLLSPGEAEQEGKRKVEEVCIFAEDSNLSAQGIYGRVGFGFPCGDWGDKERDSGEGEKSWEECVEVAYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPH5</accession>
    <name>M5FPH5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625473.1">
        <property type="nucleotide sequence ID" value="XM_040769059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPH5"/>
    <dbReference type="GeneID" id="63684121"/>
    <dbReference type="HOGENOM" id="CLU_2305999_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="100" mass="10967" checksum="03606CFB670F7992" modified="2013-05-29" version="1">MAEGSRLGNLLARCVDDASAATNKRAPHARKKRKRTKDPEANNLSVHSAGENIPLLREDEDNAVLKEHQEGEIEEVVAVVERLVADAGSGAFSQQKDWYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPQ8</accession>
    <name>M5FPQ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YMC020W-like alpha/beta hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_97335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624146.1">
        <property type="nucleotide sequence ID" value="XM_040777443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPQ8"/>
    <dbReference type="GeneID" id="63692505"/>
    <dbReference type="HOGENOM" id="CLU_004112_1_0_1"/>
    <dbReference type="OrthoDB" id="5598028at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058934">
        <property type="entry name" value="YMC020W-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058933">
        <property type="entry name" value="YMC020W-like_ab_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349:SF1">
        <property type="entry name" value="AER328WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26147">
        <property type="entry name" value="AB_HYDROLASE_YMC0-YMC35"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="370"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="523"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="781" mass="83532" checksum="D74600E7E6CEB3C3" modified="2013-05-29" version="1">MPMWVSFFSGGRNLARPLIKQGEGMEVMMIDEEATGAGAGGGVGVGPVGAGAAGGAGSGSGTTSSVTGSGVGGSGASALTAQVDAGTSLRPSSAVASFSAIQTPSSSVPNTGITNAPNSTTAKEGSKRSTAQEAAKAAGTAKEAVRAARCASKEPLKPGPGEKDVGKDVKPSSLPKDTLKITLVGGTGSKPGSIKAGTSPGSPALTVPPKAPTPEPKDAPASPLTVNPKLKKALADSKRAAPVTAKKDKAEPSPPLPNFLLPTFQDVFYHPPLSFRPPEADGKPSGALKKTMRYVNKFLGAPPNYRPVLIDPELAEYQRRLEKGKGREGEEVPVPLSASSKAMQEKSQVERMKLEGMPALMPRSWAVMGVDRLGEMRAVKRAVVVGIHGWFPGGMLRSVLGEPTGTSAKFAQMQRDALLDYLQKHDIKLDTLTEIPLEGEGTIAHRLEKLYSTLTSNELWMNDIHQADVILFACHSQGSIVTCQIMDRLLEEGHIYTGYPEQTAGETIVKLQTQGPAIPRKVQRVVCLALCGIHLGPLLYLNTSVLTQPWLHYVETAAARELFEFQDTESDVSKRYVSALGRVLDHGCKFVYIASLNDQVVPIYSGAFVNASHPLILRGLYVDGDAYSSTDFLTNLLVLCLRLRNAGLTDGGLVVHLSEATAGSLNGVGHSSAYEEMACYTLAVRFLFETNNTPGPLPPLELEPFSARESRNDYEIPWILNELVTHPAVQEWFLSEIEELRAAFDDWKPKTAALRDIRRKLEPIKRKGRKLNRIVVGPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPS4</accession>
    <name>M5FPS4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Family A G protein-coupled receptor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623472.1">
        <property type="nucleotide sequence ID" value="XM_040774238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPS4"/>
    <dbReference type="STRING" id="1858805.M5FPS4"/>
    <dbReference type="GeneID" id="63689300"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_1_1"/>
    <dbReference type="OMA" id="NIVPWIT"/>
    <dbReference type="OrthoDB" id="3354175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="36767" checksum="3638F7836A16FBD7" modified="2013-05-29" version="1">MSAVALPLEVAILVSVICQAIVYGMFLVLFGATCYVLTQKKKTTTTNVAFLATACTMFVFITINFAVSWSRIMDALFHEANPTAYLGDLTQWKEVFRTGVYIALTAVADSLFIYRLYMVWSRNIWICILPMLLLAGSLTSGIGIEVAIASLKGSGLFASGIAAWATSFFSISLAQNVLTTLLIVWRIWRVNLGAGHLGSNSLWPVIAVILESGALYSANLLCLLATYASGSFAQYICLDILVPNIGCTFCLIIVRVGLGLSKSGSQQAPTQEIGRATIGGTSARYPMRKININVARTVDVDQEDVDIERGGKEGSETDVDVFDKSQNMSYEQMHGSNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ92</accession>
    <name>M5FQ92_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_24970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624486.1">
        <property type="nucleotide sequence ID" value="XM_040773941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ92"/>
    <dbReference type="STRING" id="1858805.M5FQ92"/>
    <dbReference type="GeneID" id="63689003"/>
    <dbReference type="HOGENOM" id="CLU_111220_2_1_1"/>
    <dbReference type="OMA" id="HIILHIV"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="13776" checksum="47577B6E0A398C52" modified="2013-05-29" version="1">MAGPKKTVTASSQSPVSAITSAGQDLVKSYVDNTPKRVKIIDTFLLFIMLSGVAQFVYCALVTNFPFNAFLAGFGSTIGQFVLTAAFRAQVNPSTRSEFTIISPERAFADFCIGSIILHFFVYNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQE5</accession>
    <name>M5FQE5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_25366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623827.1">
        <property type="nucleotide sequence ID" value="XM_040774133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQE5"/>
    <dbReference type="STRING" id="1858805.M5FQE5"/>
    <dbReference type="GeneID" id="63689195"/>
    <dbReference type="HOGENOM" id="CLU_645608_0_0_1"/>
    <dbReference type="OMA" id="LETHMIM"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="71"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="47675" checksum="BB9D638AF96FE2EF" modified="2013-05-29" version="1">MLPTYVLHLVLWQVVPSLLTGLILRTLHYVLGPPPARSRVAARQYQLVYTLIMIGFLGYTFIQAANNVPKNWFQLCGADVDIEREGLNKAFRRFAVKFHPDRAGKDGEELFVRVRAGYEALQVPAKRFAYEKFGDDMISWATEDRFETLVIGLKRSVGFYIVGSLLMGVMKINSGGKDVMLIWRTFILVFCAVVEFFIVLHPTPRAFRFIFSNVLPFQYVDWLHQVSMSISAGLGHLAPIWKPRDIDQNALQQDALRLISTMDTDVIEMIHTDLNQLQIGWSILEAGNETEHRHGKYDPAMLANLETHMIMTVLENRLRSHPEIKQLWDALVVRLSEEPNKIILNGGPSMPTTPMPLQPADIPLPESADVSMISAISMDVAHSPLPPSSPLRYTTPPPGSPMPGMSRTMSSSHLPSPEPEGDVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP9</accession>
    <name>M5FQP9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63684401"/>
    <dbReference type="HOGENOM" id="CLU_1175398_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="236" mass="25348" checksum="8EB6436AB72DC83E" modified="2013-05-29" version="1">MSIALRRGTCLAFLASKAPAGSYVQVVNIDVFKQADDTFQYMLEISDGYATIRSCSAPSLTHLWLRNRLPCAPLFKWRTTSVGPSAAFGPSPSFVTLAQLITSSVVIIKKIAATGMAPLIVGNPHAIDVVALSDDPDGFIMEAAAYLAGHTPADVDKSETDSTESQERPPSSQPGLDGAIDVKPRFRAKSINNSFSLKMPALDPVESDEEGRDDLAAECIYDRKHGLNDDTSSVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQQ7</accession>
    <name>M5FQQ7_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624791.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQQ7"/>
    <dbReference type="GeneID" id="63684294"/>
    <dbReference type="HOGENOM" id="CLU_073628_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="191" mass="20107" checksum="2AE9CF41FD8643EE" modified="2013-05-29" version="1">MAPCKPQPKKPRHLPPAAAPAAPATPPPPCASPPAPPSDNLLSSLDFNPPAPPSPAPPSVMNLVSSPCLPPATDTLQPVSVMQTPAPGQKRPSEESNTPSAPKHPKQLPGKHVDNVVDLAKAMKKALTIKEKLAVKDQEILAEKAKTLAAQAQITKLMKLLEHERSKKKKDNEAVSTLILKPPGQAGHGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRH1</accession>
    <name>M5FRH1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624482.1">
        <property type="nucleotide sequence ID" value="XM_040773939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRH1"/>
    <dbReference type="GeneID" id="63689001"/>
    <dbReference type="HOGENOM" id="CLU_174998_0_0_1"/>
    <dbReference type="OrthoDB" id="5410040at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="8604" checksum="74DF19FBDB3FF7E3" modified="2013-05-29" version="1">MIPISRLLRMNASQRRSVTSTLFGLTFFAALVTVAFPCPATERNIRGLPKEHDVSSEDMFRRSNKRKWIEEVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRL9</accession>
    <name>M5FRL9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626713.1">
        <property type="nucleotide sequence ID" value="XM_040768845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRL9"/>
    <dbReference type="GeneID" id="63683907"/>
    <dbReference type="HOGENOM" id="CLU_1704187_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="17367" checksum="6CCFBDE6F95DA212" modified="2013-05-29" version="1">MSFDTVSRTRNCDVRCGRQERLEQRRNAAFTAFYRYTGSASRFATYGELEEKLRELRSAVRDLRCKVRETVDQMKALARDMESAMRGTAAQLQTGPAREVDGTEAPGGGAPILNPHSDRQESMMTTIERAPVADHPRAAVKGKWTDVNIRIHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS48</accession>
    <name>M5FS48_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Antiviral helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_81832</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627043.1">
        <property type="nucleotide sequence ID" value="XM_040776531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS48"/>
    <dbReference type="STRING" id="1858805.M5FS48"/>
    <dbReference type="GeneID" id="63691593"/>
    <dbReference type="HOGENOM" id="CLU_002902_1_4_1"/>
    <dbReference type="OMA" id="DHVNIIM"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="302"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="588"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="506"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="553"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1258" mass="140090" checksum="71B1529B358E6716" modified="2013-05-29" version="1">MEPILTKDISELILIASDSEHVNLNTREELLTELGVGRIPSKVKLHQALEDRLLQPKAKLPDHWLATYQLHWEHETSIPSLLTLAPSPAPSRLEFVRAGLEGRVTGYREIPISKQHATALTSTSLLRAPAPTTNFVRGKSSYVPFLPGGLDDILGDSANLQTVTADEASRVGLLTVPPGFTRGLRLPGEEIEEEDEISVLDSGYPSSLDKSVNSNHNGLHNENAAPVSAVGLESEIDDLLPVDRVRISAAPNRPPARRTAAVKRDWADVVDVNQQLLNFHELVPDMARKYPFELDTFQKEAVYHLEMGDSVFVAAHTSAGKTVVAEYAIALAAKHMTRAIYTSPIKALSNQKFRDFKQTFDPSTVGILTGDVQINPEGSCLIMTTEILRSMLYKGADLIRDVEFVIFDEVHYVNDAERGVVWEEVIIMLPEHVNIILLSATVPNTKEFADWVGRTKKKDIYVISTPKRPVPLEHYLWAGREMHKIVDAKGEFLAQGYKEAGEALRRKQDKEREAAGLPPVQRVGARGGAQRGANARGGQQGRGGPQARGGARGAAPPARGRGAMPPRSFQQQDRNLYVHLVGHLRKINLLPVVVFTFSKRRCEENAQTLSNTDLCSAVEKSEVHVTIEKALTRLKGSDKKLPQIARMRDLLSRGIGVHHGGLLPIVKEVVEILFSRGLVKVLFATETFAMGVNMPARSVVFSGIKKHDGRNFRELLPGEYTQMSGRAGRRGLDPTGVVIIVSGDELPDVGTLHIMMLGQPNKLQSQFRLTYNMILNLLRVEALRVEEMIKRSFSENASQRLLPDQQRKVLEVEKELKAMPELDCPVCRPDIETFYDISADLAYLNSRLIELATTHPAGSKVLRPGRVVVLRNGHFGQNLAILLKAVPLQVSSPATSPLARQYLFLALADPDTKTGSRDRPPSKVPPLWPPEPAKLPSCDPVYDLVLAPLGDVQFVTNRIVVEEFDEIADKHRILPMKHAAEALQAIALEWQDLDMLPEVEWAKFHTLDFQDTLRNRDNLHRLLSGKACVLCEGFLGHYDALHGIKMLRAQIASLKLAISDQNLELLPDYEQRVQVLKDLKLIDERSTVLLKGRVACEINSASELILTELILENTLARYEPEEVVALLSAFLFQEKTETEPVIPPKLEEGKAEVIRLAERVQKVELANKVATEDFEGKLKFGLMEVVYEWARGMPFEKITELTDVPEGTIVRVITRLDETCREVRDAARVIGDADLFKKMEEAQIKIKRDIVFAASLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT12</accession>
    <name>M5FT12_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625387.1">
        <property type="nucleotide sequence ID" value="XM_040773713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT12"/>
    <dbReference type="GeneID" id="63688775"/>
    <dbReference type="HOGENOM" id="CLU_3074183_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="53" mass="6530" checksum="BBE8973A56E9A8D7" modified="2013-05-29" version="1" fragment="single">MVHRSSFILPHPHLQLFPLPNLPKLPPKTQNRHKQRHRHRHRQRQRHTLLPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT35</accession>
    <name>M5FT35_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_68219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627613.1">
        <property type="nucleotide sequence ID" value="XM_040775866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT35"/>
    <dbReference type="STRING" id="1858805.M5FT35"/>
    <dbReference type="GeneID" id="63690928"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_1_1"/>
    <dbReference type="OMA" id="TPWYFNH"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="11"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="355" mass="39585" checksum="04B1E89A2D90ED01" modified="2013-05-29" version="1">MQRTYGPGADLRVEDLAISAGANLAFVSVVMSVCDPGEEVIIPVPWYFNQEQVLMMRGVRPVALRTRPEDGFVPQAKEAEKLVTQRTKAIALVSPNNPTGAIYPPALLARFALLCARHNIALILDETYRDFCPSSPHALFSQSLVPTLSESDASELRQELTKEEIEIASRWDWRKNLISLYSFSKSYAVPGHRLGAVVCGAELMQQVEKVLDCLQICPPRAIQLALAEQIPVLEPFVQEQAHTLAHRHAVLKSSLPSSWKLAAQGGFFAYLRHPFPSHSSYSVSQRLALELGVATLPGRFFQPEEGAEFWGSRERAREEDRWVRVGVANVDEDGVRGVGERLERAVSEWGWEVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTB4</accession>
    <name>M5FTB4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glyoxylate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626176.1">
        <property type="nucleotide sequence ID" value="XM_040773432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTB4"/>
    <dbReference type="STRING" id="1858805.M5FTB4"/>
    <dbReference type="GeneID" id="63688494"/>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OMA" id="CHSAGYD"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05301">
        <property type="entry name" value="GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF277">
        <property type="entry name" value="GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="6"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="113"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37114" checksum="BA599922D67D48EB" modified="2013-05-29" version="1">MSKTKILVCRDIGDKSMAVLRAQEDWNLVIWPHDRPADKEWVYANAPGSVGMVVTLGEKVTEELVALTGPQLKVVSTMSVGVDHVELPALASRHIRLGYTPDVLTDAVADCSIMLALMASRNVTSSQTLLRSGTWGNLGWGPYLFCGPQIGAGPGKKESTVGFLGFGRISQATLVRIAAFGVTRCVYYNSGRKDRSAEDQALADKLGLKEVKRVELDELARSSDVLFTLVPGGKDTFHIVDEAFLRKMKPTSVLVNTGRGPIVDTQALVKALKEGWIWGAGLDVVEGEPNIPADHPLLHEPRCAIIPHIASATIETREAMAMLCATNLVGGLKEGKIGVEYDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTM6</accession>
    <name>M5FTM6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626351.1">
        <property type="nucleotide sequence ID" value="XM_040773492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTM6"/>
    <dbReference type="GeneID" id="63688554"/>
    <dbReference type="HOGENOM" id="CLU_2687790_0_0_1"/>
    <dbReference type="OrthoDB" id="10631252at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="7986" checksum="4F4A564D8662B5EF" modified="2013-05-29" version="1">MATTQQPGSLNTSSAVYICAGAIVEGLPHRGFLKSEGRYSLKLLIGGSELWRSRQITTKGSRAVWDGEQDMGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTU7</accession>
    <name>M5FTU7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_55674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626451.1">
        <property type="nucleotide sequence ID" value="XM_040775343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTU7"/>
    <dbReference type="STRING" id="1858805.M5FTU7"/>
    <dbReference type="GeneID" id="63690405"/>
    <dbReference type="HOGENOM" id="CLU_003703_1_0_1"/>
    <dbReference type="OMA" id="CSICTEN"/>
    <dbReference type="OrthoDB" id="3257613at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="1">
        <location>
            <begin position="53"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="27112" checksum="1F87F00463F9B76B" modified="2013-05-29" version="1" fragment="single">CAQCGSPLQLMMRCRDCFQVLPLCSTCQVTAHVHNPFHWTEVWEGKFSRHKSLHNLGLIICLGHNGAACPASTPPALTPFVVLHANGIHNVLWAFCQCYRCPNHYVQLLCTKLFPALFDNPKMAFSFAVMKDFHMHMLCSKKSAYDYYAKLIRQTSDIILASTNDCYQELLHASQISMDLEVSQCCGEAHGITNNLPPFAATQVHSPLCPACPQLSINITKEELAKADPAKPCIPSDFCLDVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUA5</accession>
    <name>M5FUA5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="7">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_85529</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="7"/>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623714.1">
        <property type="nucleotide sequence ID" value="XM_040776740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUA5"/>
    <dbReference type="STRING" id="1858805.M5FUA5"/>
    <dbReference type="GeneID" id="63691802"/>
    <dbReference type="HOGENOM" id="CLU_004624_6_1_1"/>
    <dbReference type="OMA" id="WWASSTN"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="685"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="708" mass="76161" checksum="3ACC8AF1C43A0612" modified="2013-05-29" version="1">MRQLGTSTNYAYEQPYTQRGKPLPYTPQRRRSRAFWWIIALIGLAIIVLAVVLPVYFTIGRHSSSNSSSGTGTGSNGSGAGGGSGGGSAQPAPAFNGPISGGQGSILTFSDGSTQVYGNPFGGMWYFDPGEPFADYAQAQSWTPPLNESWRYGVDLIRGVNLGGWLVPEPFIVPSLFEQYQSGSCAPPYNAQDEWTLTNCMNQNGNATQLMEEHYQTFITEADFAAIASAGLNWVRIPVPFWMISTYSNEPFVPHVSWTYFLLAIQWARKYGLRINMDLHTLPGSQNGWNHSGKLGPINFLFGVMGIANAQRALSYIRTLTEFVAQPQYAGVVQMFSIANEPWMPVIGQHQLQNFYLEAHNMIRNITGLGQGPFINIHDGFSGMQLWAGWLTGSDRIALDTHPYFAFNAPASIAPPSSFVQAPCSGWGPELNASMVQFGFSMAGEWSVAPNDCGLWVNGVGLGNRVEGTYPGSTAVGNCTTSDAWEEWDADYKAGLMGIALSSMDALQNWFFWTWKIGNSTAGRVEAPFWSYSLGLANGWIPPDPRQAVGYCAGTAGVPMNEPFDGVLSAWQTGGQGAGTIAVDQLASYGQWPIESMNSVSTSPYLAPSDVVRLPQYTPTGAILTLPGPTFTTPSSTQTADAGDGWVDEQDQGGYWTPIGGCGYPDQWVAVGVAIPTGGCGALERRAGGEEVGGEGRGARPTEAPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUL7</accession>
    <name>M5FUL7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_23482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626841.1">
        <property type="nucleotide sequence ID" value="XM_040773260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUL7"/>
    <dbReference type="STRING" id="1858805.M5FUL7"/>
    <dbReference type="GeneID" id="63688322"/>
    <dbReference type="HOGENOM" id="CLU_019414_0_0_1"/>
    <dbReference type="OMA" id="ENIARTW"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="15"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="403" mass="45819" checksum="BD0CAAE0D5D95F56" modified="2013-05-29" version="1">MSTPVPKRLDPASRLPTSEVERMFSLLRNTRLPEKDIVPGAGETWDYGMPLARLEELKEYWLETWKFDEFLADISRWEHYTVEIEGIDVHYIHVKSGKEGAIPLLMTHGWPGSFYEFHKVMEPLSSPSSPGDPLFDLVVPSLPGYGFSAPPTRKGWTLVDTARVFNSLMVDVLGYKEYAAQGGDWGWVVTRALTAYHSDHCVLAHFNNIVEYPPVYQYPFLVAMQLLPKWAGRSVGGWVMSGSEMDALENHQKFRTIGSGYYDLQRTKPTTIGYALVDHPLGLLAYMGEKYHGWVDRSSALSDADIITTMSLYFITRTFATSVLTYYETPYALFMTQPRQKQGKTAISLFSHDVLGAPRSWVQRVLNVVSYREHEKGGHFAALEVPDIIMTDVREFVKGNWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUX6</accession>
    <name>M5FUX6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_81726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626956.1">
        <property type="nucleotide sequence ID" value="XM_040776525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUX6"/>
    <dbReference type="STRING" id="1858805.M5FUX6"/>
    <dbReference type="GeneID" id="63691587"/>
    <dbReference type="HOGENOM" id="CLU_086440_1_0_1"/>
    <dbReference type="OrthoDB" id="429183at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38483">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38483:SF1">
        <property type="entry name" value="ION TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="54"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29534" checksum="87B701BE166A2681" modified="2013-05-29" version="1">MHEEDELEQLEREIGMPSDDASTSEMPLRSQYSQTKQELAAALANRFVHSRTYIFLYLGMAALSLTTVVLSLLEGCPGIAFFVLEMIINSGMIIEVGIRLVAFGRKFWKSPFNYLDIFVTLFCIVTLITVSVSGCSGTSKSEELLDTLLLVARNVLQFTRLANVLRKSGRSIFARPAPIDLSQARRLGYALDIDLFDEDAQLAEEDPHAAAPLVPQGQSRREGQNGGVVFDAARESTVTAEGQDRMGRPDRGKVFGTDDAEEQWAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV41</accession>
    <name>M5FV41_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen permease regulator 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Required for meiotic nuclear division protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_110180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NPR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626357.1">
        <property type="nucleotide sequence ID" value="XM_040769021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV41"/>
    <dbReference type="STRING" id="1858805.M5FV41"/>
    <dbReference type="GeneID" id="63684083"/>
    <dbReference type="HOGENOM" id="CLU_021922_0_0_1"/>
    <dbReference type="OMA" id="RTDYVWK"/>
    <dbReference type="OrthoDB" id="18648at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067337" description="Nitrogen permease regulator 3" evidence="4">
        <location>
            <begin position="24"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="5">
        <location>
            <begin position="586"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="659" mass="75017" checksum="650DDCC64D7A2B03" modified="2013-05-29" version="1">MSSPAVATPLIALLLVTTSSTLGTSIIFRYPPYPSSSARLMRPLPYRQGARHGLDGMYQASHLPSDEEEEEAEEEQVREMEASGRWVEEQVEYLFPRPIWESRPTTPLSTRSSSRPPPSPKLGTKLKKDYDTVLSFSSATLAEILEPARELCYQKFELVVDDLAFVGHPVCVARDGVWRMDNIAPPSSPRNEPTEKRERISFFHLVLVLDRPDPASYHSADLSSFLAPYHAQVAFKLTAGLVHEEVRAEYVSKHCARLAEMQERVRGKGGWYDQFCDEATGEAGDELARVMREVFEAVSRDGSARVRINHIVVDVQLPPADDEDEEDESENLDLEKTVYGWVPRLRPWSALLMLEEVDELPEEVEDQEFRQRFFDTLEPTLSLSDMSNLLDLDLWADVYPLARALIYTRKAKLVDVVRENLKSVYYPTSSVEPCPADHFHDFSRAFPTLPHLATILSSLSLSPVPFSSIVPASKDRPLYLEALIWLLKRNLLQMMHVRVRLIAPQELKESFALHRARKLSMTMTEPTSSSYSPETPFLANGLLSPMLLQRTRLPVHQPGSEEDSSSDQEQEEELVPGVIVDPGRASKIERRWLDEMNRGKEQRVVDLFERLLPYFDGKTTVDEILYRTEVGRRDLREVLHLYDPYVSLEPGTELSNNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV61</accession>
    <name>M5FV61_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_81839</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627046.1">
        <property type="nucleotide sequence ID" value="XM_040776532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV61"/>
    <dbReference type="GeneID" id="63691594"/>
    <dbReference type="HOGENOM" id="CLU_001265_54_6_1"/>
    <dbReference type="OMA" id="HEAAACH"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="510" mass="55097" checksum="2EFD8EE4808B308D" modified="2013-05-29" version="1">MAQDSRSLPAVSDVETAPLLDNGRTPNRRTVRNPTPLPKLQVFAVCFMRLVEPMSIWVIFPFINEMVHATGIVSTPEEVGYYSGLIESAYAFAQFLTSYFWGALSDKIGRKPVLCIGLTGLITGTFVFGFMKVYAWMIIVRFLLAGFNGNAAVGKCVLGEVTDATNQARAFSFLSPAWAIGSIIAPIIGGFLSKPAESFPDIFGNVQLFKTFSYALPCIAGAALTSTGLFVGIFVLKETLPTKKRKVAPKHPVQEANEHHHHPHRHDYGGLNTFPVETEEEPPIEAGITLGEMLMIPSIRMVLLSYTLLGLITICVDNIFVLWMYTPLRGGGIGLMPSQIGTVLASVGVISTFIGLFVFPYLQRRIGTTPIYRFCMSLYILIVILFPTIHYLAQINTQAAVIGVGLIAVLKSMGGTVFACVMILVNMSSPSRTSLGRVNGAAQTSAAMMRTIGPTMASSLFALSNHRRLAGGMAVYLVLGALAVASAGITFLVQEATPEEAKQSQSPQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW61</accession>
    <name>M5FW61_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629008.1">
        <property type="nucleotide sequence ID" value="XM_040768391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW61"/>
    <dbReference type="STRING" id="1858805.M5FW61"/>
    <dbReference type="GeneID" id="63683453"/>
    <dbReference type="HOGENOM" id="CLU_025711_4_5_1"/>
    <dbReference type="OMA" id="WTNLHIL"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="181" mass="19243" checksum="9B2F98DEDF0DB90C" modified="2013-05-29" version="1">MHVLVVGASGRTGSLAVAEALKRGDRVTALVRNPDTFTPADVDLTSALLRVIKGTPLDQGDVHKAFLGDKVDGVVVALNSTRSSDVPWTKPTSSTDMIANAVNILLSEMLLAGTTRISLVSSWSVGSSCSTAPLPIRFVMMHTNLNYTYQALTLAEETLFHAAPDIQWTIARPSALTNGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW90</accession>
    <name>M5FW90_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Piwi-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629048.1">
        <property type="nucleotide sequence ID" value="XM_040770096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW90"/>
    <dbReference type="STRING" id="1858805.M5FW90"/>
    <dbReference type="GeneID" id="63685158"/>
    <dbReference type="HOGENOM" id="CLU_004544_4_3_1"/>
    <dbReference type="OMA" id="YVQWPCL"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="398"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="750" mass="84576" checksum="B47C8CDB70B8693D" modified="2013-05-29" version="1">MSGPDRRPKDTVGNRLKVITNMYPMQLHPDRVIYLNKVEIVPELSATAHRRNYELFDILQTKLHPQAFTPRAAYDGSRIMLSTVQYPWGAYQEFNVLTSRKRPPPPPGEKGHFIVKISANRSFPIASLANYMRLPNSIPPDEIVNYINVFLRMAPMQMHAFRGNNFYVTQGHKLIGFFQSVRATVSGPMVNMDVTSSVLWVQRPLVDTILNFLRLSDPRELALLPAHRPGAQPKVIRGFDKRGAHAIRLDEHGPTVEDYLLDKYNRRLKHPQSLCVSLSNRKQDILPVELLVIDANQFFDLKKLDNLSWDKQIKEFAMIKPSDRLAITNSGSNAMGHAQSDYVQRAGIRVNSNPLSLEGRIRDPAPVLYPKDARETIEQLLHKVAENMKQRFKRPPSLLLIFTPGETEWYTAVKRFGDITLGIPTQHLRTDKALGPRGNADYCQNVALKSYPTGFDLRPINVKLGGINFVPHSGSIQWIRGGEPLMVIGADTSHPRPGEGYKPTIAAISFSVDQNVSKYNGVVGIQRGKQEIIGNLVGMVKSAIARFKMTGPTPKRILYYRDGVGERMYEEVVREECEAIRQAFREVNEANPKITAIVVGKRHHVRLYAENPRDADQRSGNVNPGLVVDHTITSPPHDDFYLLAHQGIIGTSRPMHCIPIVDDNHLSSDLLQTLTFALTHNYQRATRSVSIPAPIYYADILCSPERARVHFDPSKDFSDSGSGSQHPTGQQYQQAFKPLASGLRDKMFWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXE7</accession>
    <name>M5FXE7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625054.1">
        <property type="nucleotide sequence ID" value="XM_040769179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXE7"/>
    <dbReference type="GeneID" id="63684241"/>
    <dbReference type="HOGENOM" id="CLU_2426982_0_0_1"/>
    <dbReference type="OrthoDB" id="3360976at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="91" mass="10130" checksum="0ACC0CC45D136701" modified="2013-05-29" version="1">MVIFRSHSKLCMKGSPDPIATFAKGSSSLLTSGIRPILVVESQALDMLDLVVLTWLEVSILFDAFQKREMVSNMQTEYILGPYSATRGIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXM1</accession>
    <name>M5FXM1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Novel STAND NTPase 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629665.1">
        <property type="nucleotide sequence ID" value="XM_040770073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXM1"/>
    <dbReference type="GeneID" id="63685135"/>
    <dbReference type="HOGENOM" id="CLU_598543_0_0_1"/>
    <dbReference type="OrthoDB" id="691197at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049052">
        <property type="entry name" value="nSTAND1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20703">
        <property type="entry name" value="nSTAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Novel STAND NTPase 1" evidence="1">
        <location>
            <begin position="230"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="457" mass="50868" checksum="D40F70DB4D0AD88E" modified="2013-05-29" version="1">MTRGLDHLRAIVEIRGPTSMSTQFLCSRWDITQHVLNIPLTPRLFDSGYYPANQTISTTPLLTSSTFVVSFMSTSKVPFQETWERWTTRATSQLAPIKEKLRNTATQVAGIADTFQELEDDSRQLALKVTWVTQVILERIPPDGPADERAKEVVLALATKVFEIDAFLRSGTKKGDMTGKRAKKVSKYHKSLDTLRLQCVEIHTDVSNNASGRSLGQQGPSLIDIPPTPEAFYGRDEVVGSIVQLLLQDKPCRVPVLGPGGVGKTSVAAAAMNDEQVKERYGEHIYFLICEGIDSEEGLVNALAVFFKLERDSNTRTALIAHLSSLGRALLTLDNFETTTQSDRQRIRELLGRIGRVPSLSLIITMRGTQPAQGLTWDTMPPLQKLPLHASRQIWKQVSNKSDEKLDELLERLDGLPLAIHLMALQRIDLPPSTLLAAYEREASIWSSPTELDDWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN4</accession>
    <name>M5FXN4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Linalool dehydratase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_89084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628141.1">
        <property type="nucleotide sequence ID" value="XM_040776894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN4"/>
    <dbReference type="STRING" id="1858805.M5FXN4"/>
    <dbReference type="GeneID" id="63691956"/>
    <dbReference type="HOGENOM" id="CLU_044865_1_0_1"/>
    <dbReference type="OMA" id="IAMRYND"/>
    <dbReference type="OrthoDB" id="9979195at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041411">
        <property type="entry name" value="Ldi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18566">
        <property type="entry name" value="Ldi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Linalool dehydratase/isomerase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="480" mass="54305" checksum="CB3A696F81940305" modified="2013-05-29" version="1">MSTTTVSTSMSSCALTPVQAGHLRHFHNLATQTSPHPWAYMGSQDPQQEWLDAYRYQVAIMCYAPGAAHYHRLPGVREPMQVLIEALVERMTRREVWGYWYLTSQSGVKVDPDLKQLRKPWADPVKEENIMYSGHLLLMVSLHSMLFASNKYDDPTGLTFVHAPIFWGLSTSPEKFSYKRMSLQKVVWDEMEKHGWLGCPCEPNAIFVVCNQFPLIAMRYNDIREGTDLAEEAIAHYRSAWPRKNDMLAVPSDGVGFSAWAGAFMHASDPVRCRELYATQRMGFFTRLEGGRLVLNEPPVAGIPTLGYVAQWLSELDTQRLDALLKHVDASCSPTWEKGGLFYPSAYDSDVKMDPFTGNAAIGYAHLNVENGQRRMWEEPWDDRRVRGYPALVGITFADGVDFLRGLWDEKRNAFVLSLRSWSGEKIMINPSVIHLPTGTYGMYVDGELKKEITCQNGEGRVDLELTVDAMGLDMVLLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYR9</accession>
    <name>M5FYR9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_39508</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628556.1">
        <property type="nucleotide sequence ID" value="XM_040774463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYR9"/>
    <dbReference type="STRING" id="1858805.M5FYR9"/>
    <dbReference type="GeneID" id="63689525"/>
    <dbReference type="HOGENOM" id="CLU_190858_0_0_1"/>
    <dbReference type="OMA" id="HRSANCA"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU01659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="59" mass="7063" checksum="2625545D920616A1" modified="2013-05-29" version="1" fragment="single">YYSATCIKGHRSANCAHNTRPLFEVKRKGRPQTQCERCRQRRKRDRSHVRCDCLTKLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYZ9</accession>
    <name>M5FYZ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623595.1">
        <property type="nucleotide sequence ID" value="XM_040767665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYZ9"/>
    <dbReference type="STRING" id="1858805.M5FYZ9"/>
    <dbReference type="GeneID" id="63682727"/>
    <dbReference type="HOGENOM" id="CLU_050078_1_0_1"/>
    <dbReference type="OMA" id="EIKMHLH"/>
    <dbReference type="OrthoDB" id="3181072at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="34136" checksum="5467330C27D829F6" modified="2013-05-29" version="1">MAEITEENPVEAAATTPRAASIPVPATPRSTHEITPPATPPQPGSPTPPGEPQLELQPEISIGFPTGDPIPVLETLLLTMQQTLHTLTSAFDTLACQTSQLATLRPALEGHHEIKRLKEQIAQQDVKMDQMRDFLSDKLTMHMADVREGLKCHVEEVMGGPVKDSVRTEVEQRVMERVAEQISQKIPAELLEDVQDHKVQLSHVRRSLHNSEARRANSLLRTNNINEPLTPLMRSNGEISPFFPHDLSSLFASPAPVARQLVSDYDLTIDPDSRERNLNKFMGHIGVGFQMVPAPPVSPTPISSLYPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ15</accession>
    <name>M5FZ15_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630180.1">
        <property type="nucleotide sequence ID" value="XM_040772425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ15"/>
    <dbReference type="STRING" id="1858805.M5FZ15"/>
    <dbReference type="GeneID" id="63687487"/>
    <dbReference type="HOGENOM" id="CLU_030805_2_1_1"/>
    <dbReference type="OMA" id="HTCIAVA"/>
    <dbReference type="OrthoDB" id="2350783at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="entry name" value="CinA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="CinA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA C-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="177" mass="18972" checksum="785045A7353C6F93" modified="2013-05-29" version="1">MSMSHPPDFVPAPILACARTLRQQLHARSQSLSIIETACGGLLSSTFVSTPGASSVFLCGQVLYTPLARAAFGGWSAEDVVAYSGPGTQVVLRLARENRRVLGADWVLVESGIAGPGRKEEWENGQPGYVALAVVGPGVERAVEVRTGGTERVGNMWEFTRLALELLWECVEQTEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ86</accession>
    <name>M5FZ86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623710.1">
        <property type="nucleotide sequence ID" value="XM_040769412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ86"/>
    <dbReference type="GeneID" id="63684474"/>
    <dbReference type="HOGENOM" id="CLU_903219_0_0_1"/>
    <dbReference type="OrthoDB" id="10557394at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="308" mass="34664" checksum="6BB9C20BBF3525E8" modified="2013-05-29" version="1">MAGYPNIPLYSRLSPRGDFLISNPTFPDFRPRWRCRRFALELRCDGHRKIYLALFSPYQIQLQCPDKHIPLPVLYMFGEAEGFDMLQAREFADTYLGDRSLDDKEVVVFSGFPCSSAPMPTRTLLQELQHELCHFDLIIPPIVPRNTRPPSRIPKFPMTASELAKRYPRIHLCKSEIENTSEGTPSIAVPLPAVHTTVGRDSDSSSSDSDSTTSNATTRPPSSSGTKPSSDDDENWQDDVTYRDMKALEEEEKEKRGKGGKGPEPPNERSDIWDKLHTYGSTIAATALFGAAIMIIGGQLWRRVHHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZC5</accession>
    <name>M5FZC5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24034</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="9"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625819.1">
        <property type="nucleotide sequence ID" value="XM_040773515.1"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_002513_5_0_1"/>
    <dbReference type="OMA" id="SVEMAYN"/>
    <dbReference type="OrthoDB" id="164902at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18801">
        <property type="entry name" value="SF2_C_FANCM_Hef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="103"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="436"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="622"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="883"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1023"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="687"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="760"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="821"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
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            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1094" mass="122140" checksum="4B96D164FB336286" modified="2013-05-29" version="1">MAPSRAGPFGRPNQRTKQWDRTQFAATGNKNKGRVKRKKRRRREDEETGEEEEEEEDLEWEQFPTSVVSSGPPPPMKLVTDPIAVREWIYPINKPIRDYQYNIVQAALFKNTLVALPTGLGKTFIAGVLMLNYYRWFPDGKVVFVAPTKPLVSQQIKACHETCGIPVEDAIEMTGETPQATRQRHWASKRIVYMTPQTLQNDLLREVVDPRDIILLVVDEAHKATGNYAYATVVRFMMAKNPHFRILALTATPGSKPKTVQDIIDSLHVGHIEIRDERSLDLKQYIHEKTMEKCVVQMGASINGIKERLLALMENTVKPLRGKDIFPDYVKVADIHPYSCKKWIDELRRKPQGRDFPWAAALLMRLHKLTFAMAYLCEESVEMAYNTLLDAAGKKLTTKEGGNKLSNDPKFRDLITEIENYRNERVTGGGPVGHPKMDKLVAVALEHFAAPDDGADSTRVMVFCQYRDCVDEIVKSLKLQQPIIRASKFVGQSSDKRGDRGMAQKDQIEIIRRFKQGDFNVLVATSIGEEGLDIGEVDLIICYDVQKSSIKMLQRIGRTGRKRSGKIVVLMAEGREETNWDAANENYSNVQETIIRGDQLELFDDDERLIPDDAKPIVRKQHMEIHPFVSQDTGGKKRRLVTDGNKGPAKRRKRNDDPNRNIPDGAFAGFISAAKLVRKGSKNTEDRLTVEGLQRDLEDDEDDADISRGRLSPTPDSSPPPEESRKAALSKISRARKSRAPDRRVSSSSTLDDLARELQDDSDDQELEAGLDNLLPPTRRVRVPRPCDIVEISSDEEPANRHPPPKPSGNGAVTFREEPANSRWLLESESENENSANTKDGAGRSAPNASAAAANKLTMELSPIQLSPVAPRTYLDVSTPARNVAANSSPDVPLVYGHGMGPPPIPAHKLTSDDSPFLIRRNSSLAKGRNTCPPNLPDKEAAPSSSPVRVKRTSKSSRSRLYSKPNPFFDVEADLSGSDHGESDDNDEEWSESDQRFIKNSPATQAVPKAEEHGIYLQGLMTQAPGRTNLGFRDGPVRRGPFGAWSGPKRHIPMSSSEADPNSEPNEYELGSFVVADDDSFEIDQVEADVSTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZL5</accession>
    <name>M5FZL5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZL5"/>
    <dbReference type="STRING" id="1858805.M5FZL5"/>
    <dbReference type="GeneID" id="63687270"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
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        <location>
            <begin position="250"/>
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        </location>
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        <location>
            <begin position="301"/>
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        </location>
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        <location>
            <begin position="434"/>
            <end position="443"/>
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        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="777" mass="85170" checksum="48E16A004DD53347" modified="2013-05-29" version="1" fragment="single">MHEEDDIIDIEGDICPVCEFECTCRAASSSRVTTTTSTVSVSARTLPHTYPAPFNTVVAPGHVPSGTFGVFALNSGPTASIFPAPSPIISQNKKSKSTITTTKKATAAVIVKKEDEEKKLGVKIKVKPLSSVNVGTSLAALPPRKRGRPSKVDLAKRQAEEARLAAVAASVMAEPDDAESTSTLTDLDDDEQGRATPRQRERRDSGEFPTFISAFTTSSAASDTGEEEDSEDSLDLDSGDDTELEEEEERAIVREHEALEGGKGSGTDAEQRRRRWAWQKERRERERRVEQGEEDGASENDIGHRRTGREEEQEEEQEEEDPELDDAHTSLELTPPDALAPVPDRIRTQEQEPYWTESEDDEEDRFFGHLSDFSDFPSDFYQRKRARGDARGEDTESDDDDLSDGSILSSVSLAEAAQSGLYDYAASAGPFLRAKRKEKRRSWSKLDSPGTMPHSRPQSRTHLNGNNVGNNRSSRSSPRTHSRQKSHAFSYDEKRHKRSKRREKRPKMVLVEDGEGRLVFGEEWEHDSWLGSGSSGDGEEMMELFPSEDEQTGKPVEAGDQEDGEGRDATEPEPERLAFVPMSQPDELLAPLPPLPPRATLTSELDDAIDMDSPESSEWTGEGETTDEEDVPGLRQEEAEAMFELGLVRTRSGERLPEVQPENILGLGVDPAVQAMLPPPTLASVIASAAAAVSVPPAPMGAPAVSFQPIQTPQKIARPVRPLPAPRTPGPGPPKLPRAYPVPSLSTWTPPVQSVRSMVFVVDGKDASGISPFAKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZT1</accession>
    <name>M5FZT1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_107740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628916.1">
        <property type="nucleotide sequence ID" value="XM_040768523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZT1"/>
    <dbReference type="GeneID" id="63683585"/>
    <dbReference type="HOGENOM" id="CLU_1261470_0_0_1"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067371" description="Protein CPL1-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Protein CPL1-like" evidence="2">
        <location>
            <begin position="165"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="23269" checksum="9BA6CA935852F30E" modified="2013-05-29" version="1">MFTSQSGSFIVLFGLTALVLAFNEVPGPSCEGTGNACSYSYVSGGGDTVTVNGFCAPNGFCADNGAACTTSDQCYDYCGNGVCGGLGATCDSTDAFSHNQFSIACYTDGGYTCNADGSTGQCVLSASLAARKRARQQLSMGPRPVSCRRDNDSLCPSLGGLTGEMECVDLASDFENCGQCGIECGSMEGGAVVECVQGKCLAMSCRRGWTLLDDECVRSITPATQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZT8</accession>
    <name>M5FZT8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628926.1">
        <property type="nucleotide sequence ID" value="XM_040768525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZT8"/>
    <dbReference type="GeneID" id="63683587"/>
    <dbReference type="HOGENOM" id="CLU_1855210_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="14917" checksum="BEEED5936C3742E8" modified="2013-05-29" version="1">MVDGRVNVVGDATLKRLPCDDPGFSGLPSVKESIVLKGFVTPASDSVYAPGQVIPDEQNLHLFKGINTAYYHRKEGRKQLARLSPIASTRLFSQTQTFQMDSFTISPATLAAAESNFTAPAKVAKSFKSSIIPLCLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5G021</accession>
    <name>M5G021_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_100410</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628397.1">
        <property type="nucleotide sequence ID" value="XM_040767451.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G021"/>
    <dbReference type="GeneID" id="63682513"/>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OMA" id="QGLEWID"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000221">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1023"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1172"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1277"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="124"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="559"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1026"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1345"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="869"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="869"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU01500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1588" mass="173969" checksum="C49FDAF6C52FBD50" modified="2013-05-29" version="1">MRRPDLRINVPEATPSSTPAISYASSPVTVPSSLPSPSPYSPTESFGEQDVADFPEDEKEQSVRPSAPEPTSKPRLMRTPVTPQDLPTAVLPPAYTDYKRPRPTTALLFSALSTKDKCTLLFPAICISLVLGGSAPFMTQVIGEAFDAFANFPVTGATSADASTLFRSVGITSAELGGLAVGVMAVSCTGSSLWVRCSERVCRTIRERVFVSVVGREMQWFDMQATQEGGDINAGGMQAKFTEDTEHVRIAISQRFPQVIEHLTTTLIALVLAFVRSPLLSLLILSAIPVMLISDGTLQRFSSKDAEAFESLKMRIPSFLSSTLDNIATVKVYNGAEPTISYLTALLGHREREDNRQSAFWAVRQGTNKFIISGTFVTAFWFGARLVQEGKLSPGSVMSVFWACLIASSNAQMLLEPVAEYLRGKEAMVRLVELVEPGPIEMDETAYEAALAQGEEDVHEEDLPPYEFPRHSSFDGQDVTDERDLEAGLPTPRPRPRSLVRSLIDLTVARKPSRAFSTTSVKTFISRPSIASMRSQTRARVSSSSSTCNSRSNQPKGAIDISHLTFFYPSRPWPPALEDVSVFFPAGELTFVVGGSGSGKSTLATLLVGMYNFPPVQDNSLGVITVDGVPLIDGAELRERAALVQFGGGVVFDMSVRDNVCIAASDPSNVSDELVQEALRMAMMHEWVEFLPGKLGCLLGESAAGQKLSGGQQQRLALARARVRDPEVLILDEATSHLDISSRFLVFSALRHWRRGKTTIVITHDLSELSPSSFAYVLKDGRVVEQGFRRDLEQVEGGEFARMAAEQAGGCGAATQSIDDEEYGWQGWDAMAEEAEDTRISRWRKHTTMQVGHLKNAISDLLHRHPEHQLGDQEEDRIADREQTPSPLPKHRSRFLPFLPRPKRASALPQIPYPRRTAAPEPEPFYNLMGASLESISDGGEDATNDYEVEYLRQTGAAVRTKRRAKSTHSERRRWTDYEVEQATKEIEIVVQDRAAALIPQPDPVVPAWTVIKRLLPLVPHKWVLVLSLFSAVANGATTPLFSFFLARLLAQVALGAEAMDFTAVTIAGCTVLGVIFGDGLTMALKIFGTEYVGHAWLTKIRSRMIGLVMKQDKTWHDENPYHKVVPVVENAATDVSELIAQVAPQFVTAATMLGGAMVWAVIIGWQLALVGFGLAPLFVLAAVGQFILSIEAQRVGAKSREVISEQYCNAIRNIRAIRGLGLEETFRKQFVLILDSAVKTGISRAWLVGCAFGLLNALIFISEAVLFLVAAKLVSVGLYTYGSMVQVMTLVVFSITNGAQVLQVIPVMTKAIHAAGGILKLLDLEKSTPSDASETVELKTDGVIRFQEVEFAYKSRAENPILKQVNFEINPGECVALVGSSGCGKTTVIALLQRLYEPISGNIWLDQQPLWDGDASKMRRRIAVVTQQTAVFPTSVKENISYGRFDIPLERIVAAAKDANSHDFIMQLPEGYDTPIGKGNGEHDLSEGQKQRLGIARALVREADIYIFDECTASLDALNESAILKTLRAVTPGKTVVMITHKLQIMQMCDRILCLQDGEIAEQGSFDDLMARRGPFHNLTTAAEWVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G065</accession>
    <name>M5G065_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628442.1">
        <property type="nucleotide sequence ID" value="XM_040768585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G065"/>
    <dbReference type="STRING" id="1858805.M5G065"/>
    <dbReference type="GeneID" id="63683647"/>
    <dbReference type="HOGENOM" id="CLU_014996_0_0_1"/>
    <dbReference type="OMA" id="WKAIGRW"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="731" mass="78344" checksum="701926B67B1B15CF" modified="2013-05-29" version="1">MSGLLQGLQGTTHSSQVSALSTHHLTSGISSLISLTVSFHHHYVILQVHSVMAKDKGKSRAMDTSPLLSPTLRPPPSTLLDPTEDPAASSSYSTFPPTAPLQRGQSYALTAFLSFLSLAGVAVLLLLLLGWSYAYPSSSSNVVHALHVRGPSSISVTNFTSEGLYLRVQGEVGIDADWVLGFRTSDDQVSWAERIRRAVGRWGVREVEALDVRLGNIDLVSTSSRALLATLSLPPLTLPLTPNLRATDSKLAPPWLKPISVDVLIHPSTDPEVLTTFAKESWAKGRVEIEAACEWVRVTPAALALGGEGGSTWGWPSLGELLTVKKGRVDTPLRMTIPSLPGFPRPGTPLKDMLNQLTIEGYAVHPLPPAQAPGPTLPSPVPGEPGKSKPILAIKGAASVPFPVLPFPLSAFDWPYEIPFLVSLLPSNRTNSTGNDTSPTPILASPEPTATLSPLPIAAIHTSPLSLPPPGKRLNITLHGELLPPPPSSPLLSAFLSAYLSGHSYPVLITSPPPYTLPTFLHPFLSTLHVSFHFPGASPPPQLLDSVQIRDTRILPSNKPNEFLISGLILAHLKLPPAFKDLIFSAKEVQPDVYITDGPPESGLGNAFARLSPPALPCSQENMTILAPLDEVPVHILPGREKRFREFVQKVLWKGSAYAGVEGEGAVRAGVGGLGEVSVAGVHVRGGSWVGRKGEEGREEEVVSGEREGLRVHDSWVDLWEETFRAWEALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Q4</accession>
    <name>M5G0Q4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_77603</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the Tim44 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630730.1">
        <property type="nucleotide sequence ID" value="XM_040776279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Q4"/>
    <dbReference type="STRING" id="1858805.M5G0Q4"/>
    <dbReference type="GeneID" id="63691341"/>
    <dbReference type="HOGENOM" id="CLU_020932_0_0_1"/>
    <dbReference type="OMA" id="NFQMEPF"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017303">
        <property type="entry name" value="Tim44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037871">
        <property type="entry name" value="TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 13" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="16">
        <location>
            <begin position="301"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU03836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="461" mass="51477" checksum="DFD4C7E4EE591930" modified="2013-05-29" version="1">MIRSIASSSSSTSVYRAAARRPTTRATALARSRQLPAPAAAFPARSNFHTSSARREELPKSPFQTFVDVLRDEIRKNRELQENVKQVQGDIGKVQDSEAMKRAKEMYERARLTSSIKENPRLRAAADEMRKAGVRVSDAVSEAMKGLEESELMKGIARASAAVSSAVSSTTEPLRNTAAYKTMADAVIEALDDSGSTRHAGYEDKEARRLRRQKRLAKAGKEGGLAARASRVAENLEAGQAVVLHKDAGKHEAWERLKETNPLLRTWANLRQQYDESENPVVATLRGFTSSIGSFFDETEMAKVTRLLRQMDPTFSVEAFTRELREYIIPEVVDAYLSADREALQMWCSEATYNVLWATMEQYLRQGLLSDSKVLDIRQVDLTTGKILENDVPVFVVTFATQEILLFRNAKTHEIVVGTEDRVEQCTYAAVLTCVESELDNEITGGWKVVEMARRSGRGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0V7</accession>
    <name>M5G0V7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_28058</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">Golgi stack membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626359.1">
        <property type="nucleotide sequence ID" value="XM_040774299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0V7"/>
    <dbReference type="STRING" id="1858805.M5G0V7"/>
    <dbReference type="GeneID" id="63689361"/>
    <dbReference type="HOGENOM" id="CLU_036311_1_2_1"/>
    <dbReference type="OMA" id="GETWNLL"/>
    <dbReference type="OrthoDB" id="2189106at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3630.10:FF:000002">
        <property type="entry name" value="Vacuolar sorting-associated 74 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="39538" checksum="4B62C9C3006CB2D7" modified="2013-05-29" version="1" fragment="single">GLTRRRGGGGAAPETTDQPPSSSQNGSLSSTSTPTLSTANGYGGTALEGSSKVAYDPRDLDTTNEENKLPKLTILEEVLLLGLKDKQGYLSFWNDNISYALRGCIMIELALRKRIAMVKDSNRRRYPLPDRLVEVVDDRLTGETILDEALKMIKSSEKMGVGSWIDLLSGETWNVMKIGFQLKQVRERLMKGLVDKGVLRTEKRNFLLFDMATHPVADARTKEDVVSRVVALLTMRTAAIPSQALHKEGIQDRYTRAVCVACASYAASVLENALQRLSFDAREAAFARCDDILAEFSTWPFGSARTESTGRKREGQGAGSESLAGLVREVKKEMAEPEDLHFEVVATVLEVFGRMDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0X7</accession>
    <name>M5G0X7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GTP-binding protein RHO3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_65013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630795.1">
        <property type="nucleotide sequence ID" value="XM_040775767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0X7"/>
    <dbReference type="STRING" id="1858805.M5G0X7"/>
    <dbReference type="GeneID" id="63690829"/>
    <dbReference type="HOGENOM" id="CLU_041217_21_2_1"/>
    <dbReference type="OMA" id="THTIMLC"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000780">
        <property type="entry name" value="Rho GTPase Rho3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22943" checksum="18ADAC16F7427964" modified="2013-05-29" version="1">MSLCGLNKGSTSFGRKPLQRKLVVLGDGACGKTSLLNVYTRGYFTAIYEPTVFENYVHDLVVDDTQVELSLWDTAGQEEFDRLRSLSYAETHLVLLCFSVDNPASLENVEGKWIEEVLEYCPGVKIVLVALKCDLRDDQPTRDRLALRGLQPVEYEQGLVVARRIRASRYLECSAKHGRGVNEVFYEAARVSISTGAKGNTGCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Y5</accession>
    <name>M5G0Y5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630805.1">
        <property type="nucleotide sequence ID" value="XM_040772334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Y5"/>
    <dbReference type="GeneID" id="63687396"/>
    <dbReference type="HOGENOM" id="CLU_084277_0_0_1"/>
    <dbReference type="OMA" id="SNEYCAA"/>
    <dbReference type="OrthoDB" id="2536450at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34862">
        <property type="entry name" value="SPARK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34862:SF1">
        <property type="entry name" value="SPARK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067489" evidence="1">
        <location>
            <begin position="18"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="254" mass="25834" checksum="2C29A57C93BB23D9" modified="2013-05-29" version="1">MFARTSLVVLLAGLAAAQTTPSISTQCTTALASILANSNAASCLSLGDVIPVLTLSSNTSLIPSITTWLGDMCVAQACSNSTLDSVTSSVIQGCQNDLITNGVLPQGTTISVSQAQQDVEIAYTPAREVVCSKSIGNWCLINTLTSIQTLIGAPLSEATLFSADWTQLASTLDTSSLCTDCNQAAYATLRTPLNLQGTPIETVISNRCGSTFVSGSVPADVTLGGVTTTHSGAEAVRAALAGLLGTAGIAALLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1N8</accession>
    <name>M5G1N8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_109879</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626674.1">
        <property type="nucleotide sequence ID" value="XM_040768960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1N8"/>
    <dbReference type="STRING" id="1858805.M5G1N8"/>
    <dbReference type="GeneID" id="63684022"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="YATNEWY"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="36566" checksum="B2A2B870A6C6115D" modified="2013-05-29" version="1">MGWKSDQPLSLSSPAVLGANGFVGLHIVKQLLEGGCIVRGTVRSASKGEWIKNKFSAHADHIEYAIVEDITKAGAFDEAIKGVDAVVHAASPVPDNLDGTQIYVPAVKGAESIFNSLEKSTTVKRVVLTSSFVAMMEPHEHGFTYDETIWNDNATKMVKENPKGPKGLPGATYYLAAKTDAERIAWNFYNAHKGKLNWDLIFGPILQDEPNFSNSLVYRNALLEKAGNLANDHAGFWIDVRDVAKAHMLSLQKDKAGGERIFIAGGPYRWQDLRDELSKRNIPGVLTERVPGEDKYDIADLSKSADILGMTYRSLGDTLVDSVSAYKKSQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2B7</accession>
    <name>M5G2B7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ima1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_117616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626909.1">
        <property type="nucleotide sequence ID" value="XM_040770421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2B7"/>
    <dbReference type="STRING" id="1858805.M5G2B7"/>
    <dbReference type="GeneID" id="63685483"/>
    <dbReference type="HOGENOM" id="CLU_036826_0_0_1"/>
    <dbReference type="OMA" id="CQTNQML"/>
    <dbReference type="OrthoDB" id="5966927at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034992">
        <property type="term" value="C:microtubule organizing center attachment site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071765">
        <property type="term" value="P:nuclear inner membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="356"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="587" mass="65188" checksum="849686E2BC2FAB60" modified="2013-05-29" version="1">MWKTAARKPLTCFFCLTQDATPNLNPYYWKCNACEQWNRRNTNGEIVPDPGSQNVYMNHASWQRRAALPDNAFPPGTPWSTFCTQCVTNQKLIVEMLANYIPEESDSGYHAALANIAAYRADLERRYPPLCEECRPRVEAELKKRSDEATAEIRASMATSSGPTVSGTPIKAMKEGRKEGGDLSTWEVYVWRIRGFLWILGLVLSVARCVKVLVHPSEVPQGASAVREVLITLISIIWTSWNPKWLRYRRYVQAGVPTQVVGSHIWTAFQIIIYFFRLLLSISYLTLTSAIFSEPREVSQILGAISLTADTLLNYIAYRTIMIRKIPTVKRTLAPLGAAPPRQTFHENALKELRLSDSPQLTRTPTRQQPPRRAKTASPHFTPLQPNSIIRSSSLAPAQTSATILSPPRFPSTPSLAGSSIATEDDITPMDVDPPTSQSTFTDIYLKPQTYPPRFSSTGLEDLLSNWSLRDASPPALDRRKIGTAWQEVGVLELLEGLTLCVGWTSGQMRAMQIAWACIAVLGVYRLGQMQRVEVAVAAGAALLRAALPLPILAAWMGTSPAVEALLWDVVCVAVTLTARLSVKRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2D4</accession>
    <name>M5G2D4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629269.1">
        <property type="nucleotide sequence ID" value="XM_040768443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2D4"/>
    <dbReference type="GeneID" id="63683505"/>
    <dbReference type="HOGENOM" id="CLU_915340_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="304" mass="33090" checksum="A54CF37C1ED8873D" modified="2013-05-29" version="1">MSFKIYIDPSPQQPSNIMRSHTLPSPSSLFSTLIPSLPPASSTSPTRIPTTTTDTSIPRTGKENVDPLTGLPATRKLPKSKSKSTSRSKQPLAPASAPTANKPKSKVKPPKHTADSSKPQLRKQKPAAKRPLSPSLRSPPPPAAAWPSPPLFDQTEHFNRLAQQLTVLPLADVSLAYAVQPQLEAEVDPTMIPLPESPKEDRIWRPFVTEAGTAQVEVHLELEKAGDGERPAKKQRLEGRKTLRRAVTSPLGRPVVGHQVGTVRATERTPHLPQLQIQPQPKLQSKNTSELGDTPSLPIWADLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G320</accession>
    <name>M5G320_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase substrate phosphoprotein PP28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
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                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="entry name" value="HAP28"/>
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    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
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        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="187"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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</entry>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
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                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
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                <person name="Wiebenga A."/>
                <person name="Young D."/>
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                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="14885" checksum="1D94859B6FDAC7DF" modified="2013-05-29" version="1">MVPLWQIQCLIGNYDTPVPCILNGCSGIVSISEQCCKQIRLAYTPIKGQCMESANDLVSQLLGHIPNLRIGISGLNFYVQAFILPNLPFHLLLSCPFHVLASCITQDYTSRKQKIQITCSNSHQTINLWTQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3A0</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
                <person name="Hesse C."/>
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                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
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                <person name="Sabat G."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="HOGENOM" id="CLU_110318_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="176" mass="19496" checksum="A646C6D2A3CBB7AE" modified="2013-05-29" version="1">MAKPNTHKSAAKPKDEHAAMLKTAAAIVACMHKDVEDPRFLPLVKYLDIKPFSNMVALLLNSPQSALVHDLPEKWVQLFAANQQEELAALSVPPEEDEEEDKEEKQFNAMLSGFLMSLVSLASPLGKLEKAKAEAKEMMLAKAVMPHLDEGTMQMPLVTRACRRPSKADSQCRVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
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    <name>M5G3C9_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_106787</name>
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    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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            <taxon>Dacrymycetales</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
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                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
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                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
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                <person name="Glotzer D."/>
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                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629619.1">
        <property type="nucleotide sequence ID" value="XM_040768337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3C9"/>
    <dbReference type="GeneID" id="63683399"/>
    <dbReference type="HOGENOM" id="CLU_1686505_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="17689" checksum="E4B1A18D843D2CAD" modified="2013-05-29" version="1">MSSRLNEFLTNEDIREEIVAMLSDDLKAYSSMRVLDRFLTACYYGIYSTLQASATKFNAQSFLKSRGEFQASPIDSINASAAGQKWKEFMLKTFFQSKAEPKADDVIAAIQHPFIVAEFCKDETRLRRARESMTPEIKTGMVLDLKVDGHGTDRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3N4</accession>
    <name>M5G3N4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyruvate carboxyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631740.1">
        <property type="nucleotide sequence ID" value="XM_040767971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3N4"/>
    <dbReference type="STRING" id="1858805.M5G3N4"/>
    <dbReference type="GeneID" id="63683033"/>
    <dbReference type="HOGENOM" id="CLU_1077774_0_0_1"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000002">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28473" checksum="3D675C3F8BFA833A" modified="2013-05-29" version="1">MEAGEKNNLSHRFKALEKLREYLQAGGGLKECVVLMRKTSPVDDRRSLVTECAIANAFCALEAGATHIDTSVLGIGERVGITPLGGPVPEYVRSKYNLPMLREIKNLVAATVEVSVPFCHPITGYCAFTHKAGIHAKAILNNPSTYEILKPEDFGLTRYVPIGHRLTGWYAVKSRVEQLKLNLTDDQIKDVTAKIKELADVRTQSMEDVDTPLRVYHSGVESGELEFGQSSNLGRDTFSAVCSRSTRVRARSAWPRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3R2</accession>
    <name>M5G3R2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627389.1">
        <property type="nucleotide sequence ID" value="XM_040768679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3R2"/>
    <dbReference type="GeneID" id="63683741"/>
    <dbReference type="HOGENOM" id="CLU_1045929_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="266" mass="29400" checksum="95564F2C8616919B" modified="2013-05-29" version="1">MSIFQAGEQVARLALDQHARQAANPESRETINVTKLKNIDRQAVVHGVVLHAAKTGTQLNSSHWRLFLQLVAQDPSLGIQGSASVELNSKARQADGGTVLIITSRTYPFSDVKNTALCRKFYSFDGWLEIWAIWNDVVTYEQTMAETFPYNIPRGNLYGRRRNGLLTYVLSLSPYMIYADVLLLNQHYVKDTSNGTCTPPHTEMLIKNKMCNETNVEGEDAAAAAQAAADPLVVANGELGHFTVAAKPNGFVRILEGGWTLLHLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3V5</accession>
    <name>M5G3V5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629789.1">
        <property type="nucleotide sequence ID" value="XM_040772566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3V5"/>
    <dbReference type="STRING" id="1858805.M5G3V5"/>
    <dbReference type="GeneID" id="63687628"/>
    <dbReference type="HOGENOM" id="CLU_1434399_0_0_1"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701:SF1">
        <property type="entry name" value="UP-REGULATED DURING SEPTATION PROTEIN 1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="21419" checksum="32A87683BA0914FD" modified="2013-05-29" version="1">MSSLTDEEVEQRAEARTNRKIADLEIQTASLQQLTASLERERHKQSLEIRELRRKLRESRLSLPPRTFQALKTTWEADGLDLESEEEEDHDKADPVWERVKGLVDDMLNVGGRAVEEGQEFIKKRDKSGGGVVRVLTAGELEEMEDSKEQDQGDTGEYGEGQHQPSFRKKGDVALDWLSSNGDRNETPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3X0</accession>
    <name>M5G3X0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631840.1">
        <property type="nucleotide sequence ID" value="XM_040767989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3X0"/>
    <dbReference type="GeneID" id="63683051"/>
    <dbReference type="HOGENOM" id="CLU_2032072_0_0_1"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13666" checksum="D8DE18583ED0C3B2" modified="2013-05-29" version="1" fragment="single">MQGLATPDDCDMFGHMSNSSYAKTLDIMRMQFGADFFLTWFSSYKGTCPMGAADYSFIKEIPIMGRYEIRSTIGGWDHKWLCVVSYFVSYPKIRQSGSPEQVLTPPAPLPAALFPPNAILHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G539</accession>
    <name>M5G539_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sec20-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_103863</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEC20 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632270.1">
        <property type="nucleotide sequence ID" value="XM_040767828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G539"/>
    <dbReference type="STRING" id="1858805.M5G539"/>
    <dbReference type="GeneID" id="63682890"/>
    <dbReference type="HOGENOM" id="CLU_063105_0_0_1"/>
    <dbReference type="OrthoDB" id="46868at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005606">
        <property type="entry name" value="Sec20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825">
        <property type="entry name" value="BNIP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825:SF0">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Sec20 C-terminal" evidence="12">
        <location>
            <begin position="176"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="46549" checksum="30548E08315B6934" modified="2013-05-29" version="1">MYTASLRSSLPPTPTISRLPISINPHERPSMPPLPPSPSAQLLTLQRHLSSIRTQLPRLLSSPSLALQAQYTSELREDLEFVTRGVRALEVVLDGEEGEGRMRAELGKMRAELDRLKKETRAAVLKSKKNLDSRNKRLELLAGAPEDLIQEKSGTSLRARSLLSRPRRSDDALTDKSNEVTLALRRTTALMQQEVERSVLSTQLLAESSRTLHSASNAYSSLSGLLGISKTLITALERADWLDRALIFAALAVFLLVVAFIFKQRVIDRGVRLAFWWVRWLPSFGDEGLDIESAAERKQKVREVLTSVLTTTSTALAAAMSMSMSMEGGKGASVRVETVTEIVTVSKFVDVESTGNSLEDGSVLPSPTLRTGTAHGVSPTEAPEPAAQEFAFIVDSFPDEAMPLEDPYTAVPPAEASPPRQRVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Q0</accession>
    <name>M5G5Q0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625985.1">
        <property type="nucleotide sequence ID" value="XM_040773573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Q0"/>
    <dbReference type="GeneID" id="63688635"/>
    <dbReference type="HOGENOM" id="CLU_882840_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067494" evidence="2">
        <location>
            <begin position="19"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="315" mass="34235" checksum="F6F1E36320394F2F" modified="2013-05-29" version="1">MQITNAIVLAVLTAGIIAAPLTHYPGDNRVVDPYMAQPEEGMGNGAQDNSSQLHCECEHDLKESPSNPTTSAHLPLSFGVLRDMLMAEKVVDVFGEEMGTSFLQGLHAGQMAGSTQLDFDRPHHIELVMFEQYPHHRFRHHRHHSRFGRLGYFGHHHDRRERLLRLIRAHSFSEPSLSEETATAIPPWDEAATVHTSEDEAAAGQNPANAAVDAPRGNPAAETAVSLAPRDNTEAPTTQPVAPPPYTPVAPPPYTLVAPPPYTRVAPPPYTRVAPPAFTAPRSSPRLVYGPSHGVPSHDPQHQTSAHQTSASSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Q5</accession>
    <name>M5G5Q5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DASH complex subunit DAD3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Outer kinetochore protein DAD3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_114925</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630439.1">
        <property type="nucleotide sequence ID" value="XM_040769909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Q5"/>
    <dbReference type="STRING" id="1858805.M5G5Q5"/>
    <dbReference type="GeneID" id="63684971"/>
    <dbReference type="HOGENOM" id="CLU_118180_3_0_1"/>
    <dbReference type="OrthoDB" id="2443965at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013965">
        <property type="entry name" value="DASH_Dad3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08656">
        <property type="entry name" value="DASH_Dad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU03545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="125" mass="13830" checksum="F8CDA265F4D52DAF" modified="2013-05-29" version="1">MTTATSTQVSTAQDDAVLVQNPYASHPQLSSLEGEVLWEYAKTARLIRKLSGITKELGGRSNESLLAQLRVLERKMGLVLTLFKASVWAVIVEGEEAEQEMLAKQQEEARLSAANTSHLSEHDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Y4</accession>
    <name>M5G5Y4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BAR-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_114535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631028.1">
        <property type="nucleotide sequence ID" value="XM_040769841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Y4"/>
    <dbReference type="STRING" id="1858805.M5G5Y4"/>
    <dbReference type="GeneID" id="63684903"/>
    <dbReference type="HOGENOM" id="CLU_072096_0_0_1"/>
    <dbReference type="OMA" id="TRFCAYF"/>
    <dbReference type="OrthoDB" id="446293at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07591">
        <property type="entry name" value="BAR_Rvs161p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000014">
        <property type="entry name" value="Protein hob3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037429">
        <property type="entry name" value="Rvs161/Hob3_BAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="17"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="264" mass="30090" checksum="B8BDA3495AE4D50A" modified="2013-05-29" version="1">MSWAGMKKAMNRAGTTLMQKTGQIEKTVDSEFQDEEGRYRQFEKEVNQMQKESKAYLDAMRAMTSTQARLAETMEIFYNAADRGSENAMACHAYKQAVVELDNGIARELDQPYRTGILEPVGRMASYFPTINEAISKRNKKLLDYDAARSKLRKLIDKPSDDPTKLPRAQEENDQTKEVFEMLNEQLISELPQLLDLRVPFFDPSFEAMIRMQCKFAEEGYDKLGGVQRYFADSIRDEYAAGQLDGQVEAVLQEMKDLTIVGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Z6</accession>
    <name>M5G5Z6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isomerase YbhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628119.1">
        <property type="nucleotide sequence ID" value="XM_040773033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Z6"/>
    <dbReference type="STRING" id="1858805.M5G5Z6"/>
    <dbReference type="GeneID" id="63688095"/>
    <dbReference type="HOGENOM" id="CLU_038716_1_0_1"/>
    <dbReference type="OMA" id="HHIVEYG"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF7">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26253" checksum="5B8F07F398D635BA" modified="2013-05-29" version="1">MTGTLLAVPLTATGLKAPTHPILKFPFIGPGPNLERQESSHPHQVYQRSSSEILIPDLGADKIWRLAPSASGEWEIKGEVACASGAGPRHVQLVASDLYVLNELNNTLSHYTLPGGLGTTASVRTTQPCTLLPTPPGAGAAELLLHPAGKYLYATNRDSGDAKGDTIAIFKLEASVLALGAKEPKWVKEVHTGLEHIRGAVIKELDGKVWLIAAGVKGGGIKVFEVVGGENLVEVAHAAIEKVTGFAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G671</accession>
    <name>M5G671_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626160.1">
        <property type="nucleotide sequence ID" value="XM_040770510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G671"/>
    <dbReference type="STRING" id="1858805.M5G671"/>
    <dbReference type="GeneID" id="63685572"/>
    <dbReference type="HOGENOM" id="CLU_616803_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="48595" checksum="B1E0728CA36473EE" modified="2013-05-29" version="1">MTSMIAVRYAPNALVEPRSPIAPSYPAQASKSASHPEMTHQGSWSPVIPHPPNLAIHISYSALVRLTNYTTTTQSYRSLHKTQHIKMRYAYLLAALAFTAPALAYPLAKNDQDTNIALPTEQQPSEVQAVSSHHSHYCHGRHHCHPRHRHRHHHGPHRHHHGRHGYWHRHHRHYRHAHEHVDKESAPSSPTSPSPEPSSSSPGPSSPSPEPSSPSPEPSSPSPEPSSPSPEPSSPSPEPSSPSPEPSSPSPEPSSPSPEAPSKESAPSSPTSPSPEPSSPSPEVPSKESAPSSPTSPSHVPSSPSPKALSARSFEDDQVGSITPRKRGPGAWVVAEVHSSDDPHSLANRWKTLKWGFFLRKHWHHSPPWMAHIRFSEPPMPEDDTQSPMDGDFAFSEPEDDREFMFEDDTEINPPVAAGAAQMRLFKTSGPSHLSRSSSDHRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G687</accession>
    <name>M5G687_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631093.1">
        <property type="nucleotide sequence ID" value="XM_040771030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G687"/>
    <dbReference type="GeneID" id="63686092"/>
    <dbReference type="HOGENOM" id="CLU_696430_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="396" mass="45597" checksum="027733138D47FB5E" modified="2013-05-29" version="1">MASLSLPDLLQAIQRQPEALRVLQSIVSQPPSENTERSVLFNEHRLKTLSQWLMSTNRPPHSPDIASLTDRIGSLEQQLARQGRPSRRKRPRRSDDPDETDHPLNQHQVGHVNVAEKFCADMTAEEMSRLVRTELYAIIGFDSPHGTMPCKGEFTVDGKAVPDFNKKLTAKENYLIQLRAAEVVQQMQQSNPNLIPLHMQENWMSTETLIRLAQSTWQHMKWIWRAERRRTRTAQFKSGALCFAAELNLDADLLCQELIHEDWVGEECSAAEEGEDQEEWENDLLNGSGFTAEQVVANGILLWELRRPVWMHTAVTTNKRRASNIIRVDLGNTSALMPMEMPYRFMIDAEWQVVESEHYKGFHPRDAQPSCLTDTMRDELRNPDNAYIHTKFRTTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6M7</accession>
    <name>M5G6M7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626315.1">
        <property type="nucleotide sequence ID" value="XM_040773481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6M7"/>
    <dbReference type="GeneID" id="63688543"/>
    <dbReference type="HOGENOM" id="CLU_2654458_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="76" mass="8489" checksum="BDB202D10A23CE06" modified="2013-05-29" version="1">MYIAELAAACESKLHGERYIHCQPWTGSIQVRKTSVDVVKWGDVVSVACDPWGGVQSDDTMLWDGLSRSFGRDTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6X1</accession>
    <name>M5G6X1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_44936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632895.1">
        <property type="nucleotide sequence ID" value="XM_040774615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6X1"/>
    <dbReference type="GeneID" id="63689677"/>
    <dbReference type="HOGENOM" id="CLU_1176098_0_0_1"/>
    <dbReference type="OMA" id="QFSELAF"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="193" mass="21494" checksum="C348E2169BEE740D" modified="2013-05-29" version="1">MWADPLTCATIPSSGLPADRRVSAYCFAPPCVTSPQLSKLCSSLVVSFVFGQDLVARLSLGSVRDLVRCAWWLSYGTNDPSESCASIMTRIASFQSGGGTREEREDISQQFIALRKTLEANMHMADLFPTGRVLLALRKGDLPSDYQAETHVEDLQVFEVNDVEVVFGQITFARDMLSCHLPHHYDHILHEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Z4</accession>
    <name>M5G6Z4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632915.1">
        <property type="nucleotide sequence ID" value="XM_040771464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Z4"/>
    <dbReference type="GeneID" id="63686526"/>
    <dbReference type="HOGENOM" id="CLU_2170976_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="110" mass="10275" checksum="FB1A3AA6B88CECD1" modified="2013-05-29" version="1">MLSAGCLTCTLTEAGITAAEFDAACGAAASTLSGSTSTTATRATNTAGISTTSQRVSSGSSGSSTRSSTSTSGSSASSPSTTQSRAAAVGTKSSGALLAAVAVLVGIVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7J2</accession>
    <name>M5G7J2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RFX-type winged-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_45233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633070.1">
        <property type="nucleotide sequence ID" value="XM_040774633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7J2"/>
    <dbReference type="STRING" id="1858805.M5G7J2"/>
    <dbReference type="GeneID" id="63689695"/>
    <dbReference type="HOGENOM" id="CLU_019757_0_0_1"/>
    <dbReference type="OMA" id="MIWLREN"/>
    <dbReference type="OrthoDB" id="10056949at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039779">
        <property type="entry name" value="RFX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619">
        <property type="entry name" value="RFX TRANSCRIPTION FACTOR FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR RFX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02257">
        <property type="entry name" value="RFX_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RFX-type winged-helix" evidence="3">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="684"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="715" mass="78629" checksum="4AD819E37F8917FF" modified="2013-05-29" version="1">MGPEQTLEELAQAVRNATTTSASDRAKQSFVQLWLTSNYQVYPDGNVPRQGLYMSYRRVCEEYQIPHINTATLGKAIRLCFPNIKTRRLGVRGNSKYHYCGIRPTNASEAEWLQRYATTSQGWDISALPGRPSSSGRAMGGGGQYGHSEEEEDEESDETDNDGMGQSLTIRKGHPHFATYGEMDDRTPTTGALMHQQQQSRPVTGTGQFSANPSPSPLSASPQPPQGPFSASTLPPSVRQINGFPDISEALGPQTGPPTPESLVAQEMWTLFIGHLDSLLDAVRQLRFDQFELNIRAFWTGLGPQHREVVHVPTVQALMARADALVYDEILESLRAQIFMPLPPTAMQQMKQMADKMEKILLSAVEGYQANFYESKIELGARFGHLVTRFLDMFQVAQALRSVLTNQKQILDMQTAWQQIDFDSVRNQTALVCNCRHEVLVQILETEFPQLLANLYTAPEPVKTVTEWVDDTYRRIMQGDFGPIESSQARSVLIRWGFVTSQVMRDLTIRSDPAFGAFQILKLFLDDWIALHVLRDVALSTNSVAASIDPQQQYLNMSPMPGDDNIFPNEYMQPFQAPAQPAAAQPTTSSTMMAALTADNTYPEPLDGSAPGAGFSFPLGTLDFSNLDPQASGGNTVSSNTGVEGLMSAMSSMSSTTAAFPEYSTPGGNSFEVEEYTHDYSMSNVATATPGHPPVPKIEDTTGGGLTSPHSQQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7L2</accession>
    <name>M5G7L2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_45366</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 10">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="10"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633075.1">
        <property type="nucleotide sequence ID" value="XM_040774639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7L2"/>
    <dbReference type="STRING" id="1858805.M5G7L2"/>
    <dbReference type="GeneID" id="63689701"/>
    <dbReference type="HOGENOM" id="CLU_012907_1_1_1"/>
    <dbReference type="OMA" id="WYANCPG"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000006">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU06181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="35474" checksum="7CB91D5864B055F6" modified="2013-05-29" version="1">MTCRDALNQAMEEEMLRDQKVFIMGEEVARYNGAYKVTKGLMDKFGEDRVMDTPITEMGFAGLAVGAALAGLRPVCEFMTFNFAMQAIDQIVNSAGKTHYMSGGEVHCPVVFRGPNGAASGVAAQHSQDYSAWYGSVPGLKVVSPYSAEDCKGLLKAAIRDPNPVVFLENEMLYGHTFPWSQAAQADDFLLPIGKAKVEKEGSDVTIVAHSIMVDRSLDAAAELEKEGISAEVINLRSIRPLDIDTILKSVKKTNRLVTVEGGFPAFGVGSEICAQIVEGEGFDYLDAPVERLTGADVPTPYAAPLEALAFPDAPLISKAAKRALYRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7V8</accession>
    <name>M5G7V8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Low temperature requirement A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_89007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628864.1">
        <property type="nucleotide sequence ID" value="XM_040776888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7V8"/>
    <dbReference type="STRING" id="1858805.M5G7V8"/>
    <dbReference type="GeneID" id="63691950"/>
    <dbReference type="HOGENOM" id="CLU_362091_0_0_1"/>
    <dbReference type="OrthoDB" id="3198598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101:SF1">
        <property type="entry name" value="LOW TEMPERATURE REQUIREMENT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="74916" checksum="A48B570C90E3B4C3" modified="2013-05-29" version="1">MAEVLHSEDGSKLEVGTRTPKLENEINGEEVEYLNVAGPLLPLLAQQGPQEGKEKGEVLWVAEFQRATEYLNLLYDLAISSVLSVFGNNHHILNGASIAAYFSYFLIIWWVWASQVVYDSRFQANDWIHRLFKFLQLGAFTYIGVFAQNFDPSNVIAPPDSSSSSSIAQYQSAKAWKGAAIAYALSRLLLSFQYFYVALITQAPERRKRWDSFVIPIVTTLLSATFWLISGLLTLSSAAKLVLGYGGLVIEVVVTIAASTRESAIAPSSGMLGGRFADLTLVILAEGVLSIVTTLAEVVSGFGLNSGGSKLNGYSECISSLVVVFGTWHFIFHAFDHEQRFRNRRTSLVWAFLHLPLHFVILLLLLSLNGVAVYGNIDGGVTVLTNDFVQFLDQVGLVSTSSLDGLLTNNVLLQFNKLGLSPPVKDELDRVNQQAINLDFYINTTGVPPPAFDPFVEQLTYFSYVMWTAAQSYSINLGPNTTDLYNQLSATSSDWNGTDQDMVNLETSTNTTYMQFCFSYTVDIAAPAQLFLPSAGALIILAALLTVFRTYGIPDEEEKTSQLWDVSGQIRSIGRADIIPIYPKLARAPRKWQVVVAVWDWLPFTLHMIVGIVLCVLAALDIPLNLLSSPIDSLLNVGWVLPLVAISYGGLMVLDCIVLVLARKARGGRFIHRIHEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8B5</accession>
    <name>M5G8B5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_114725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631284.1">
        <property type="nucleotide sequence ID" value="XM_040769864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8B5"/>
    <dbReference type="STRING" id="1858805.M5G8B5"/>
    <dbReference type="GeneID" id="63684926"/>
    <dbReference type="HOGENOM" id="CLU_1026803_0_0_1"/>
    <dbReference type="OMA" id="DYRTSTH"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30862" checksum="8A644051D7672AED" modified="2013-05-29" version="1">MAYVQPTINGTRTVAGGHPGQGSSPADLDETTGTNGVDDDDDDDDDDDEEEEEEEEEPKEMDEELAEHAVSLATQWVLASNGQRILSRISLVNLGDELLDRFVRPPSTVEIVDYRLVESGLNDRDLYGPRAIDFEAAQSIIWERLQGRILVGHRLWESLYLLNIRHPLVYTRDLALYLPFQPLLTPNTPPPLNSPNTPDIIICPLPQLTRRMLAPHWLPVGPRVDPTEYAEAQMLLYRRERQRWEDCLTRGIPISAPPPTQFRNEEQNFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K2</accession>
    <name>M5G8K2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768105.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63683167"/>
    <dbReference type="HOGENOM" id="CLU_2849644_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7359" checksum="7CE6835C2052956F" modified="2013-05-29" version="1">MTYNFFGTKNREYTFIIDSGSTTNWITGMPFLHQYYVAFHYTANMMGFGTRNLGASAAQSKPFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K7</accession>
    <name>M5G8K7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627000.1">
        <property type="nucleotide sequence ID" value="XM_040771260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8K7"/>
    <dbReference type="GeneID" id="63686322"/>
    <dbReference type="HOGENOM" id="CLU_029462_0_0_1"/>
    <dbReference type="OrthoDB" id="3419411at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="463" mass="51427" checksum="501F5F412A5A62A7" modified="2013-05-29" version="1">MDTCATTNAVTAQSYTLLSDLVTPGWNNSTMWSKVASSTPITTTTNQPVNFNDTSLVLPSGVDNLQAVIKDLHNITSEPTSLVLATDPLPEKYHTLKQKARQLELSESSHDDLTQEMFNKTRDSAYLEGIENEAEEEEEEDKSGKSAHPLFLDNLTYILSTSHVKEIPVLLKSASTFIEMVQQWQCSTHKEEMKAEQTYTCLEGTWKKQCCKAAELGAKAPNKPKRPAPIMVYIILSNTSSIAQDDKSKDKVKGKGKGKNPKKSNSPHTSLEEQRKGLYGQADIVLPGGVHWDPSDQDWSFWNLALSRKVPNVTETEPPGNIMDKWITISETCQSEGPLCQATCPLKCQAVDLYLLLGQDLCGPPLDGIDVSIPSPLLKEWLEKSVDGNPQWNSDQHNFSQYLDAFIKAGLYHLGELAAVGSMDKLLDTYHLSKPKERMLCGTAVVLLNYARVDFKQLCHQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y5</accession>
    <name>M5G8Y5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_117290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627130.1">
        <property type="nucleotide sequence ID" value="XM_040770354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Y5"/>
    <dbReference type="STRING" id="1858805.M5G8Y5"/>
    <dbReference type="GeneID" id="63685416"/>
    <dbReference type="HOGENOM" id="CLU_379474_0_0_1"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999:SF17">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="205"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="576"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="581"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="622"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="730" mass="74721" checksum="A8DA5857C78F489A" modified="2013-05-29" version="1">MNPPFPVSPSQSQAKIDQVLDRLQRLALESSAPIPHPPIPSHSQLHIHQHHLAQAHSQAKDTDSLSSHSSHTHSHTLSSTTGTTSSASSSPPSAAPQSSPYPSPQIPAFPPQPAHFHPQHAVNPNLANVASLYRLGVPSRLQMPAFDGRCSPLPGDMGMLTPGSASLPLGMGMGMGGNPGMGQNAPMPVGAPQMGGASGKAYSYRPGDWICVSPACSYPNFGRNEYCNACRSPRPSATGGGMPRAPPPAGLYFGPGEAPRFAAGRMNGLPLGTGGGVGTVYNPAVGLVPAGGVGMGNLGAPGIPGVTGVTGSAESGRSPMIVTPSGRAFASTGTRKNISGDDLNPVVIFWPDNEPMPELGQVRPCMLGLAQPPILNTGNKGPIEHQPGDWYCQKCEHLNWRRRKVCQNCYRFAEGNEDDTTLARQAECISVLIAQLVAAKKAQEAGVLLNLSGMMGVPAPLAPPAPVPVPAPAPALALGTASSSDGQLTPCPKTQETYFSPPSERRPQPALVQVPAPVPVPAQRRPLPATGVLYTPPALAAAQAYEPYSPPPLARKPASAPLSASPISPLRMPPAAPLAPINTSPTLLRSVPNPNASASAGGKRLSPSLTPLDPKSARTIWAPSSASGSPPKSARTNIWGPASSVSSGSPPSRWPDFALPGKMMQGTPSPRGSIAESACGSTSASGGSGSVCDAPRMGNAPACGPGMSPVASPPTAGGYKTHPRLAGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Z6</accession>
    <name>M5G8Z6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23216</name>
        <name evidence="1" type="ORF">DACRYDRAFT_25715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795929">
        <property type="protein sequence ID" value="EJT96475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627145.1">
        <property type="nucleotide sequence ID" value="XM_040773158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Z6"/>
    <dbReference type="GeneID" id="63688220"/>
    <dbReference type="HOGENOM" id="CLU_2605973_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="9186" checksum="55E6D629C52381F7" modified="2013-05-29" version="1">MVCTGGVGHALDARLGRHPRRSPPRQYTRRLRFENQALRLRICILSWQLPGIASVSRQLSIKDFRDPVLDRNEFMQVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G923</accession>
    <name>M5G923_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629266.1">
        <property type="nucleotide sequence ID" value="XM_040770131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G923"/>
    <dbReference type="STRING" id="1858805.M5G923"/>
    <dbReference type="GeneID" id="63685193"/>
    <dbReference type="HOGENOM" id="CLU_1107088_0_0_1"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="2">
        <location>
            <begin position="13"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="27985" checksum="9E141EB6550FC89B" modified="2013-05-29" version="1">MAALLPRTPASPILTRFFARTHKKALSALPDNIRTTPPRPIPAANPFIPRFNPDSRCWAPPEYSKRRQIELLKAAQDEGFSQWMPCAEGERVGGGRKGQRAAHAAAAAVTAHESVQEGGVEEIGDQGGSTIVASASTPDAPTSSLLVAAVAQKAVKRQHKSKTNTTPQQITDPEAPFLWIGIPNPVYAHETVYGAKTRQKWFKGHRWEREKVERQKRVKKNIETMDERIKDWRDNRVSKRQEARLQSGLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G947</accession>
    <name>M5G947_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_61705</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632163.1">
        <property type="nucleotide sequence ID" value="XM_040775679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G947"/>
    <dbReference type="STRING" id="1858805.M5G947"/>
    <dbReference type="GeneID" id="63690741"/>
    <dbReference type="HOGENOM" id="CLU_032731_1_0_1"/>
    <dbReference type="OMA" id="GIGWNWR"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067572" description="Wax synthase domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="10">
        <location>
            <begin position="159"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="37877" checksum="191179FE139975B0" modified="2013-05-29" version="1">MYNAHTLATAALLASDLLVLHDPASDFSNKDGKFFALPGLSWTNIKWALDLSMNLRGIGWNFEAKHLWTSMGKNESRLRFTLRQLLGMAGCLLVMDLAQTLYRNRSACYTGGSVYQDGMAWQVVYNLAEWINMGGAMLLMHALAAAVTVPLFIYKQEDWPDMFGRIRDGYTVRKFWGRTWHQLHRHFLTAHAKFFAQDVLGLTRGKKLTTYVELLIVFFISGIVHASGAYAFLRTWSGAFDSILFFTLQAVCIACEDHVIIIGKRLGLKDTMWTRLIGYAWVVTWITLSNPIRAESLVHGGLWDQSDQPQLGLVQGVIEKSGVVTFPQRRILHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G989</accession>
    <name>M5G989_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_22068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EJU02432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772661.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G989"/>
    <dbReference type="GeneID" id="63687723"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OMA" id="NQWQWLM"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="59291" checksum="F81A215386CEE838" modified="2013-05-29" version="1">MSDDAFEKEGSQTAADSRDDSHPTAVKYDAGVDVAVLLMEAHEGDSEQELSKSTASKIRTKLDWRLLPLLFLLYTVNAMDKSTLGSAAALGILTDAKLSSDELNNLGSAFYIGYLIAEYPQVYAMQRLPVAKWIAFNIFLWAVFIGLQAACTNYGGLFALRFLLGMSEACITSGLMLVTSMFYTRVEIGERIGWSFQCNGFAMIIIGFIAYGMGQVPPSHRPAPWQWLMIIMTIASVIVAALFWWGFPDNPTTARFLTEQEKVDAVRRVKGNQAGIETKVWKRSQFMEAMRDYKTWIFFFMIAFADLQNGISVQYSLIIGGFGFSTVQTTILNVPSGFTQIIGVTCACLMLRFFPNSRSIIALIWWIPSIVGAICLLSIPLENKNGLLVAYYIFQLGGAPSFVMMLSWVTVLVSGHTKKLATNAVFLVGYALGQILCTQFWKSQYRPRDTVPWAIILASEFVTISLIILLRVLLIRENKRRDALQTEKAEDEFGYVEQVEDGQVVRRKVEKRLLDLTDWENTSFRYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9L3</accession>
    <name>M5G9L3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9L3"/>
    <dbReference type="STRING" id="1858805.M5G9L3"/>
    <dbReference type="GeneID" id="63682540"/>
    <dbReference type="HOGENOM" id="CLU_568606_0_0_1"/>
    <dbReference type="OrthoDB" id="47730at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911:SF13">
        <property type="entry name" value="TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="480" mass="52695" checksum="43774B8BC81F8D52" modified="2013-05-29" version="1">MTDTEILTIAFHVPTGLEDYALSSILHQLGEHISAQIKTAAPLHSSHVLIRFPSNALLTQAIQIYATGALWAVYEAFICVAEVSLDDVHPVLGEEFWEREREMGRKARENQRENALRKRLARAHKEQTQEPKEAEEGEPLHAERPTPTAGELLLLSSLHKLVTSHSSQLQESISLLHPPPSFRATFSNPSRLLPLSTLRRRDIERHLGDTLSLFLPIDQWSVNLTNPGVDVHVRLLPLGPKWTSHTLPPFLPAPELTQPPLKSQHFPPSLWALLALSFPPPPTPAHRLPPLQGPTSLSPPIAHLLALVYISLFPNSVVVLDPCAGTCSIPRELAALAKERKHPIFVLGGDISLSALADPCQCIEKIQYTALESLPLRFVDGFITDLPWGTRHLSPRQVKVFYPKLMLHLAEVMRAEGRGGGGGGRGRGRGCGCGGRGGGGVLMSAARGGLDRALHGWEKEGVREVRVGGRVVWVWGVRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9L5</accession>
    <name>M5G9L5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629451.1">
        <property type="nucleotide sequence ID" value="XM_040772476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9L5"/>
    <dbReference type="STRING" id="1858805.M5G9L5"/>
    <dbReference type="GeneID" id="63687538"/>
    <dbReference type="HOGENOM" id="CLU_1280386_0_0_1"/>
    <dbReference type="OrthoDB" id="10469770at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="216" mass="22573" checksum="84A36BE36E312970" modified="2013-05-29" version="1" fragment="single">MAVPLQGQASVVPLVQLPYAASPAQYITYVPYASTAGARSPASPIPPMSRASSSGKLQSPRRSRAMAYATATSPPTTPVAQIPIRVAIPPLTVPLPPTIAARTTLATSTPRTRTTSSSAPVSPLYHPSVTRFCPHCNTRVPTSHPYQQCASCQKPLSAYPQRPPSVVPEADGFAIPGIGGRPAVTQRDLGGGRRTAPTTPMYSPAPPGGYTPTHKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Y3</accession>
    <name>M5G9Y3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_106753</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629581.1">
        <property type="nucleotide sequence ID" value="XM_040768321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Y3"/>
    <dbReference type="STRING" id="1858805.M5G9Y3"/>
    <dbReference type="GeneID" id="63683383"/>
    <dbReference type="HOGENOM" id="CLU_1107087_0_0_1"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031037">
        <property type="term" value="P:myosin II filament disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903013">
        <property type="term" value="P:response to differentiation-inducing factor 1"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04515">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051852">
        <property type="entry name" value="Alpha-type_PK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992:SF2">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="6">
        <location>
            <begin position="14"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="27482" checksum="483452F11957CE78" modified="2013-05-29" version="1">MSTIGINQIVVVQEYFVSLDEFNCHPILCTQGDLVEIILQLLVFAEGLSKRAYWLRQKTDPLSMSAYMAKVLYNDGTGTKPSPLANWEHLQQELVGAEQAQDIFAVFQEQSLEVAQSTIMKAGLPPHQGCSWLVEPYLSQEKPIKFSGTDIAGRHGGENHAGSMVDALAHFSYIHSMQSLVLVDLPGIPQVNTHPGLPGNVPIVLFNVQTHTQEGSSGLGDQGQAGIDNFLVQHECVALCVQLQLNTLMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA95</accession>
    <name>M5GA95_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629766.1">
        <property type="nucleotide sequence ID" value="XM_040772560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA95"/>
    <dbReference type="STRING" id="1858805.M5GA95"/>
    <dbReference type="GeneID" id="63687622"/>
    <dbReference type="HOGENOM" id="CLU_933914_0_0_1"/>
    <dbReference type="OrthoDB" id="3357985at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33896" checksum="87C57214BD7463A4" modified="2013-05-29" version="1">MELGRAADKWQIEVALWILRREVMSPRFDHLPLRVYTFCCEMDFEDEIELSASKASLSDPRDPCRRDQIGNSSALDLIRIVMMHDAVKKPANLPEALKRNDATRPVPAWHQPILYAWDPLFKRNDADLVVKSSDGVEFRVFSLFLREASPRLADLITTSGASTLPTNASCAKTMEWPEHAGTIQALLRYIYPLGEHPRTEQSTDELMAVLWAAHVWKIEAALRPLRAAIISPERVSSDAMPSAAAWSSIRKEKSLQCMRSRLTQYTTTRLPISLVYLPWIGFTLLTKERGALLQLRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAK0</accession>
    <name>M5GAK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F1F0-ATPsyn F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAK0"/>
    <dbReference type="STRING" id="1858805.M5GAK0"/>
    <dbReference type="GeneID" id="63687413"/>
    <dbReference type="HOGENOM" id="CLU_152700_0_0_1"/>
    <dbReference type="OMA" id="TIDYQMH"/>
    <dbReference type="OrthoDB" id="5561579at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019727">
        <property type="entry name" value="ATP_synth_F0_fsu_mt_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10791">
        <property type="entry name" value="F1F0-ATPsyn_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="10715" checksum="934A92BE7361B0F7" modified="2013-05-29" version="1">MRTTLIRRALEGLIPPKIASPHSVTGGSVGAQMSGVVDFYSKLPKGPAPPMSTGIKARYWDGKNASAAPIYGTILSLMLLGYSLDYFMHLRHHKNKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAR4</accession>
    <name>M5GAR4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632359.1">
        <property type="nucleotide sequence ID" value="XM_040767849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAR4"/>
    <dbReference type="GeneID" id="63682911"/>
    <dbReference type="HOGENOM" id="CLU_2497851_0_0_1"/>
    <dbReference type="OrthoDB" id="3267885at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067716" evidence="1">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9914" checksum="F65EB1777985EBB6" modified="2013-05-29" version="1">MSRSGQTTIMFSLLPSLLSLCTSLKLLVSEPMYGKYMRLFLLIQAYRTAENLRDDKKYITSFLNAGWTNDMMTIANLLYLVLYTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB19</accession>
    <name>M5GB19_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_106354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630076.1">
        <property type="nucleotide sequence ID" value="XM_040768253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB19"/>
    <dbReference type="STRING" id="1858805.M5GB19"/>
    <dbReference type="GeneID" id="63683315"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="DEREWPF"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="292" mass="32021" checksum="B2FFE74327465FCB" modified="2013-05-29" version="1">MTQGLKEPKVWLITGALTGFGRLMTQLVLSHGDSCVATSLDPSALQDLSTQYGTKLLNLHLDVTDASGIKSVFSAAKAHFGRLDVVYNNAGLGFYGVVESVPEEAARKLFDVNFWAVVAVSKEAVRFFRDENPTKGGKLFIMSSTVGLWPISQIGHYAATKHAVEAVTLSMMRELKPEWNIQTTLVEPGWFLTPILGKSSGRWYDCPELYGGDERTGLRIKGIGKPGDPEKAVELIYSVAQREKLPEHLPIGELVIKSLRSLAKRWTAVADEWEVEGGKTEFGEGTPLDVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC20</accession>
    <name>M5GC20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630526.1">
        <property type="nucleotide sequence ID" value="XM_040768142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC20"/>
    <dbReference type="GeneID" id="63683204"/>
    <dbReference type="HOGENOM" id="CLU_1299663_0_0_1"/>
    <dbReference type="OrthoDB" id="10438891at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="23909" checksum="C887ADA566DEF9F1" modified="2013-05-29" version="1">MAFYIPLQPDPQPLQRGALYVVLFHLPPLHPPQYHWALGFISAAGEVFSYHAADEELRGRSPTQSETFEISLAHETKCGNLAEWIYERRADGPWYEARSRHVAVMIGRFGGAEPMLASMLASVPLMAAEEDRAEASEFGYRLWLRAAVRLLVARQIVQFRAPNDAAVLESECLFIGDQYHERLRPGLRLWDSYYDAEVSFSGKLNLGKGSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCC9</accession>
    <name>M5GCC9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonylcarbamoyl-AMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_113285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633583.1">
        <property type="nucleotide sequence ID" value="XM_040769603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCC9"/>
    <dbReference type="STRING" id="1858805.M5GCC9"/>
    <dbReference type="GeneID" id="63684665"/>
    <dbReference type="HOGENOM" id="CLU_031397_0_1_1"/>
    <dbReference type="OMA" id="RCSNISH"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Threonylcarbamoyl-AMP synthase C-terminal" evidence="7">
        <location>
            <begin position="101"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="264" mass="28674" checksum="CB2C1AA3AEADEE95" modified="2013-05-29" version="1">MAPLQEAMHDLLDRQLPIAVPIEIIYGLAANALDAEPVAGIFSAKGRPADNSQIRTPLAAIGGKIRLILDGGACDVGVESTVVDGLPSPGVIKVLRPGGLTVEELQRVLGPGTKVLVHKRDYEDPEIEHVPTTPGMKYRHYSPTTPVVLLLRTPPPEGKKAETIHDILDELSPQQEDFRVGVLAFSNSPITLACITTHYHTHRYSLGNRNEPSEAAHRLFDGLLTLDAEGVDVILVEGVEEDREGLAVMNRLRKAAGEVRYIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCD6</accession>
    <name>M5GCD6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628585.1">
        <property type="nucleotide sequence ID" value="XM_040768467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCD6"/>
    <dbReference type="GeneID" id="63683529"/>
    <dbReference type="HOGENOM" id="CLU_1209794_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="229" mass="24404" checksum="398998D02E77E23E" modified="2013-05-29" version="1">MPGVKYGHMTKLHTAPTGHSSAFRAARPGGEAGYQTLWPLCTCFVAYRQGREWATVTGKHSYTPRHLAPSRAGQGFWYVCAVLLSTISMIVQQASALMPQNSLPADGWGGTGPQGVSKRAVRVLALDRQHPEPNGEGMRKTKSTKMEHTPPRCTTAARAGRRGACPAVRAIQNEELTLASGGLSLLPARVAVILLAEQHLAGQSARAGREQAGQARKMDSTPTVESALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCP6</accession>
    <name>M5GCP6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628795.1">
        <property type="nucleotide sequence ID" value="XM_040772750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCP6"/>
    <dbReference type="GeneID" id="63687812"/>
    <dbReference type="HOGENOM" id="CLU_3092908_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="6975" checksum="11862CEE69FC420C" modified="2013-05-29" version="1">MPLVQIASVEPIVPEIRISQYPALSPSTPLGSRVASPTKNQVRAAGWTAYTLQEEVRADVRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD54</accession>
    <name>M5GD54_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_48427</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631161.1">
        <property type="nucleotide sequence ID" value="XM_040774833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD54"/>
    <dbReference type="STRING" id="1858805.M5GD54"/>
    <dbReference type="GeneID" id="63689895"/>
    <dbReference type="HOGENOM" id="CLU_020262_4_5_1"/>
    <dbReference type="OMA" id="MDLIPFF"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000192">
        <property type="entry name" value="CTD small phosphatase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="10"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="184" mass="21146" checksum="C7B03E33919BDEFE" modified="2013-05-29" version="1" fragment="single">RPLLPPLEAKLAGRKCLVLDLDETLLHSSFKMIPHADYVVPVEIEWQWHNVYCIKRPGVDAFLREMGDHYEVVVFTASLSKYADPVLDKLDVNRVISHRLFRESCYNHKGNYVKDLSRLGRPIQDMIILDNSPASYIFHPNNAVPVTSWFNDPHDTELTDLCPFLKDIKDVEDVRGVLDGNLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD57</accession>
    <name>M5GD57_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase II assembly factor Rtp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_113279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tango6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633509.1">
        <property type="nucleotide sequence ID" value="XM_040769602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD57"/>
    <dbReference type="GeneID" id="63684664"/>
    <dbReference type="HOGENOM" id="CLU_005991_0_0_1"/>
    <dbReference type="OMA" id="RAYTIHI"/>
    <dbReference type="OrthoDB" id="39591at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019451">
        <property type="entry name" value="Rtp1_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039600">
        <property type="entry name" value="TANGO6/Rtp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959:SF1">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10363">
        <property type="entry name" value="RTP1_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase II assembly factor Rtp1 C-terminal" evidence="3">
        <location>
            <begin position="844"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="729"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="209"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="744"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1063"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1160" mass="125964" checksum="D712ABBF739C8188" modified="2013-05-29" version="1">MRRPRAAAQPKGQEESTSLFPSLLRAASILASLAPLPGATAAHVSTDQLRKSLGTFEKELGGWATVFSGEELGEDDLPSAFTGLSVGDGKRKGKKKKHVEEDSVVAKEEASDPAEWTALYREVIMRGLWVIEQLQAGLVLDQTRAAVEGKEDKEKKDVKGKGREVEPQKPLVLGTKDMQHIRTLLTLIFQHLTKLLSDRLALAAPDTTSITRTSTTPTSVSTVATPSPASPVTPSQASSPNTNGLRFYPPPAPVLRLLHRLFSLIYTELPQPPPKPLSWDAQILARTALPLPAPTYRPQHTHISNIIFNRNSGALLAACVVLGWAPQEAGIFPGEGKQGEEEQEVLREWTRRLLYTIPTSQGLVILGLLHSASPLPNQLLPSYALLQLKDFLCALILRPDGPRALMDVVLGEKGPQTIDSSTATKLDHVSLTLSAVPRQFTPRSYYCILLPRLMLLIRPPPGCELPAPVPTSHVRAAAGTIARMIRQQRGICMTLLARNVLAPFFPPTHAYSKDWPAHLPRPQALHALQALSILLANVDPSPVLWSVLLGEILPPLWGLYEFLSTQPTADPVLRELAQGLIEGWARLVGDDVAVSGWIGIVQCWKGWGYGEGGKWEWALGPEGPFVRALEGKEEDVNVLQVHPDPLTVVAVLKKVARKEVNAELFVKMLDLYGEEHGKNGDTADSMLYLQYVLAMADSLGHMILSKPEHVLSFILHALESTVKPVIESKETLGSGSSPWKVVGDSDDEDAGQDEGDGEDDGGDTMARTAVTLLLAVLEAKESFPPFALPMLNSIYQHLDTLSSHPTLSQSAREARLVLAARRAGAMRPQAKEEDEVREKALEKYQEALRLVQDQLLPVRAHGLTLLRQLVTPTQPTAPEELALDPALIPGILDVFLLSVQDEDSYVYLNAVHGLSAMLQGPAEGKYEMGRLVLRRLVELYVLGLGLGLGLESGRMSMSTAEVDKRLRIGEAISQGVAALGPGVGKYVELIEPSMLLVTRTPAYPTVLRGSSLSILSQCVTSAPLSLLPFYPDLLSCLLDLLSLETVAQGSKAAKDGEAQALKRQREDGKLPDPSDLDPAAQDPKLPAFRRSAAYLLVTLLRQAAEGGFVDNVLDMEGRKRVVGVLRWVGDVDVDIQMRGKAKEGLGIMDGVVRSKLGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDI5</accession>
    <name>M5GDI5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_113956</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631451.1">
        <property type="nucleotide sequence ID" value="XM_040769731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDI5"/>
    <dbReference type="GeneID" id="63684793"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067663" evidence="10">
        <location>
            <begin position="23"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="14"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="506" mass="54905" checksum="C4F3C437FFDEC96F" modified="2013-05-29" version="1">MPMPSTGIIMLWLLSGIAIINSCVNGYDGSMMNGMQSLAQWQSYFNTPDGPTLGLLNAIFNAGGTVGVFFAPYVTDKLGRRLGIAIGSVIILIGVILQSAAQNIHQFIGGRFVIGYGLAISGNAAPILVAELAHPHFRGTITGLYNTQWALGSIIAAWVTFGTFSINGQAAWRIPSAVQAAPSVILLIFLPFMPESPRWLVDKGKSDKARAILGKLHGNGNINDPLVNLEMEEIEEAINFERQNEKASYLELVATPGNRYRMFLGITVGLFSQWSGNGLISYYLFKVLDNIGITDSKTQLLINGGLSIYSWILANTGAFITDRVNRRPQFLTATIGMMASFAALTAATGVYNENGNNAAGIAVIVLIFVYSAAYSLAWTALTVLYPTEIMPYNIRAKGLAVSSLAVNLALFFNSYVNPIGLDNIGWKYYFVYVAWLPIEVVTIFFFYKETKGRTLEELAVIFDGEVAAVAGNTDAVTHPDAEKAYIEQAEKVSSEEQFETSSTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE59</accession>
    <name>M5GE59_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_76170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632001.1">
        <property type="nucleotide sequence ID" value="XM_040776186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE59"/>
    <dbReference type="STRING" id="1858805.M5GE59"/>
    <dbReference type="GeneID" id="63691248"/>
    <dbReference type="HOGENOM" id="CLU_364897_0_0_1"/>
    <dbReference type="OMA" id="AGWECAQ"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000007">
        <property type="entry name" value="Basic krueppel-like factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="482"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="512"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="413"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="629" mass="66323" checksum="E460676535E96C3B" modified="2013-05-29" version="1">MFGPPRNVDDDASSQHPGDEYDPAAYDAPLHSAALSVASDGTQSIFEIQQQSLAAFANPQDYSGYQPGTGGSPASSARARSRASSVSSFHGQSPSLAAAQPPNPISDFSALSFNHPASPFVRPPPTPPMQRSVSPFVGISEPSPPPHLMPQSPGLKPQSPPQLMIPDGTPGGASLAPPPHAHTNNGLLAVGGPQINLTPATPISALTAKPGDNQRGFQDILRDITTGRGPTSQQGQRFTNQANPQHPVWPPPASQHAQPPLLPSLPPFGAQFGNYAYAPRVRSKSETMNGRPQFAGPPPAGWECAQGMGMPPQQPQQPTTMDPSILLPGSSQSQQGMMGGYGQPTAFFPDQQGMPMGGMAGQGHRRTGSMSGSQPPMGFMPGHQRQSRSLGGSPNMIPQNLGGMQGYLPTINPNDGTLLPPMMREASMGPDRRGRRLSHGSGASTPYSRSPSPGASRPLRDMVTTPATAAASQGRRTTKATFICPIPGCGSTFTRSFNLKGHLRSHNEERPFKCHWPGCEKGFARQHDCKRHEALHLNIRPFTCEGCGRNFARMDALNRHLRSEGGNECAKTQQPLTEESVAAAVAAAGLEGLPSVGQIEGALDDSDAVPMTAPSLEGDMENLSKALVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE85</accession>
    <name>M5GE85_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arabinanase/levansucrase/invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_13277</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632061.1">
        <property type="nucleotide sequence ID" value="XM_040770968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE85"/>
    <dbReference type="STRING" id="1858805.M5GE85"/>
    <dbReference type="GeneID" id="63686030"/>
    <dbReference type="HOGENOM" id="CLU_013784_2_0_1"/>
    <dbReference type="OMA" id="TTFFCQD"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="448" mass="50437" checksum="175F428E8CF1F7D7" modified="2013-05-29" version="1">MNDPCAPGYDPATGLYHLAFQWNPKSAAWADISWGHCVSRDTVHWSTGDSEKWKEMRPILTPSHTYDRKGIFTGCFVPEGLKGQQGILTVVYTSVSHSPIHYRLPYVRGNGAPQQLNVRAWRDPFVDTWPALSRSVGRNEGTKWGIISGSVEGEGPNVFLYEIGDRDLTKWTFVASLVKFPCGLPASSAWTGDIGKNWEVCNFLSHLSSSGHRDRVWLTMSAEGTQRWGLQTGGILAKDELVRTPRWSLWMAGRVEADVRGQPKVQHEYGGVLDHGCFYASNSFWDPVRERTIAWGKFVLPYQWKFRFDETAGWILEDDLPPALRDAQAWAGVISLPRELFVLRIPNIVGTLRTSIQEIGSFSAQENGTRGWEVETLGIRPIQEVESLRKMAKEMRVGQVRLGKGRNMVSLGLVEKTWEFQGDVGVWGKVAKVGLYMRHSEGRRSARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEE6</accession>
    <name>M5GEE6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_46726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632256.1">
        <property type="nucleotide sequence ID" value="XM_040774723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEE6"/>
    <dbReference type="STRING" id="1858805.M5GEE6"/>
    <dbReference type="GeneID" id="63689785"/>
    <dbReference type="HOGENOM" id="CLU_059252_4_0_1"/>
    <dbReference type="OMA" id="DKYTASM"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="5">
        <location>
            <begin position="109"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="159" mass="18179" checksum="1E92740DC43AF395" modified="2013-05-29" version="1">MVTLTTSDNETFTVDKKVAEKSVLIKNMLEDVGESDQAIPLPNVTASVLKKVLEWCEHHKDDPAPPENEDKDDTRKRTTDISEWDQKFIAVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKLFNIVNDFTPEEEAQIKKENEWAEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEH3</accession>
    <name>M5GEH3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630147.1">
        <property type="nucleotide sequence ID" value="XM_040771075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEH3"/>
    <dbReference type="GeneID" id="63686137"/>
    <dbReference type="HOGENOM" id="CLU_657242_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="418" mass="44983" checksum="ACD0669F7743D10A" modified="2013-05-29" version="1">MSGLLKAAKKKANTVSQAVNWKKVDEEKHAYHYKLHRDVVAAELAQAEDGLLQAGTDLLTNSSPIDNLTLSASASVAGAIAAMSAIAEQATHGGEVNKEAEDEGDPTTVTMAPSTGPAMKVVNVMHKKKQVKLTVAEKKELEHLAAISYKATAGCILCCHLCDTTVDCLNGGGNVCIAMTHVMLWMCSSCFQAFGNSCTTHKAQKIACSLFWLLLLVDSPTMWCGVEDRVMITLSSYYTLHEVTTVQFCQINFNMESHSNNPPTCCGTGDHHPNLNTKYAPTLAEAGAGDHHPIFDTKDSPALAIVVAGYCHLSDPELDHCKVQAYMQTYMHMTGFLEACFNVADVIGLCTGCEDIRSKVNEGFDAAINARCIKAQEQGAQIGHTIVCCLEAPADCVDAALKGMYHLWNPCVSHIISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEI0</accession>
    <name>M5GEI0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_88241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630167.1">
        <property type="nucleotide sequence ID" value="XM_040776842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEI0"/>
    <dbReference type="STRING" id="1858805.M5GEI0"/>
    <dbReference type="GeneID" id="63691904"/>
    <dbReference type="HOGENOM" id="CLU_521770_0_0_1"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="522" mass="57258" checksum="6CF6116C3D3A0FD9" modified="2013-05-29" version="1">MNQLSAGPSTLYSFQFAQDVPIQPFQFFQNSQYLNDVPATPNRECEAVPAPLFPIERGLSARGREKLPASIEQDASALAEGLKADLSSNLEEKKQEEERREKETKALTDLTGEVEKVIRKVYHLSNPGTYWGCKGKETREREDDASTTAVARSEQEREAIAKSDELMHSHSNSQNFKSDSHNVALVTNPSTAIQDPLAKKKAIQAWIADVHVQCNGETDLPAPQWATKIGSSPCSDADRSSYEDTLVGDESIVPEKLAGDENVEDDIERMSLTAEIPMGAYITELVRRTAISVSQLKVAACYLIALNPTIQTLLDTKRKAATVIAAGFPVNNYTVSPLLCARRTLVSCLIMASKFLGDNVYTMKAWSRITGMEAPDLVQCECAIGVALGWRMWVGANINNLKNDVFTRTLAQAKAPIPTPPELVVPQASACAQLSVQVLQTVLPVVPAAYGEPRSAPKETTVTKKRSRALTSTGSDREIDLRVHKKKVVERFSLPMGRPIGCATGMVMPEQVEEHRLMAEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF27</accession>
    <name>M5GF27_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630672.1">
        <property type="nucleotide sequence ID" value="XM_040772300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF27"/>
    <dbReference type="STRING" id="1858805.M5GF27"/>
    <dbReference type="GeneID" id="63687362"/>
    <dbReference type="HOGENOM" id="CLU_043293_1_1_1"/>
    <dbReference type="OMA" id="FFIFWDR"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="170"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="331" mass="38730" checksum="553E9E1F30855298" modified="2013-05-29" version="1">MSNSSIYYPFPPYDLVPEPVTFPIYYAPRPSVIPGVSDAHLSLAAPVLTYWGYSLIFHIFDTYPEYFPWLDKYRIHDSEEMKSRNLVTKWQVLRAVVFQHAIQTLLGLWWMEEVKESTNHAAAMRQLAPWVVSLSNLILGPRIARTLLQQYGTSIVEFVYWWAIPTIQLLFATFLVDTWQYFWHRAFHMNKFLYRQFHSHHHRLYVPYAFGALYNHPLEGFVLDSVGTVIAEAVSGMNVRQATVLFMLATFKTVDDHCGYAIPWDPFQLLFGNNADYHDIHHQQAGIKRNFSQPFFTHWDYILGTRLTRKDFEASKNKGKAAQEQKKLKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF46</accession>
    <name>M5GF46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_19310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632856.1">
        <property type="nucleotide sequence ID" value="XM_040771448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF46"/>
    <dbReference type="STRING" id="1858805.M5GF46"/>
    <dbReference type="GeneID" id="63686510"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="MWGTNVL"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="41440" checksum="3DF7220931527231" modified="2013-05-29" version="1">MPSKSGRLSTMGHLQQMFPPSPSFSPARDIPPLPGIRALITGGTSGIGLSTARSLLAAGAHVCLMARSSGKGERVLRELSAEGYSQRVTFIPLDLGDLASVRRAATAYIEANDRLHLLINNAAILLPGSGSMEVSAQGHDAQFATNALGHWHLTMLLLPLLRETVCLLPIVPSPASSVDSLPSLARTVGSHASSSSGRSSTAADGQPHAQPVPVQTQEEQELAAMTRIGVRVLTLSSNAHHFAPASTLNWWAIQPSVPRDVRDTVRKRAGGWGLYAGSKMANVIISNYLARTLGPSTGIVFAAIHPGGIKTDLSRSAPKWQNVLTNWMLYPAEYGALTTLWAATCENARHLNGGYCIPWARLGAARGDTQDWAVQDRLAGLLEEMRVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFN6</accession>
    <name>M5GFN6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633366.1">
        <property type="nucleotide sequence ID" value="XM_040767751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFN6"/>
    <dbReference type="STRING" id="1858805.M5GFN6"/>
    <dbReference type="GeneID" id="63682813"/>
    <dbReference type="HOGENOM" id="CLU_105927_0_0_1"/>
    <dbReference type="OMA" id="GVMDMVQ"/>
    <dbReference type="OrthoDB" id="5593278at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="16673" checksum="12D13F72B7DF7324" modified="2013-05-29" version="1">MSSIPLSTPLIPTKSLSKEIDGIHTELNIQSYSDRVLVLITQLNKVGCFIQASLPPTAPLLPPLPGRLPEPAVGTVLTPLFGAAPSEHLHDLYSLYASQVAVLLWTSEGGGGRKPVVVGVALQRQKEGEEGSGLTDRERKTFEGVMRMVQECFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFQ3</accession>
    <name>M5GFQ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
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        <property type="entry name" value="ER"/>
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        <property type="entry name" value="GroES-like_sf"/>
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        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
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    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
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        <property type="entry name" value="ADH_N"/>
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        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PKS_ER"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="19"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="38098" checksum="8C3D2B09C7158A4F" modified="2013-05-29" version="1">MSPDLPSNMRALVQTAYGRPSKALTVQTLPLPPYAPTSDDLLIKVKRASIAPAEWGFLAGYHRPLGILSLPDRLGFDFSGVVVRAGEAAQAQGWKEGDDMFGALPLAKKGTYAEYITASSEYCAPKPVNMTWEEAACLSSNGMTALQGLERHEGAREVAFVTGGLGGVGHLAIQLLHEHFGFKKIITSVSTGKVEQIKTLYPYVEVIDYKTSTPAKVIPAKSVDLVFSTIGAPAQWTPLLATQRPTPTLIEITTVPGAPGMEASWGLTLPWYARCMVNTAAVLIRPRNPKGSKYVAQYTAYIHRDLEVLNKEAAEGRLKVMTGREFTIDQGAEAFDLTHKGVVGKVVFHISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFQ4</accession>
    <name>M5GFQ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_105385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFQ4"/>
    <dbReference type="STRING" id="1858805.M5GFQ4"/>
    <dbReference type="GeneID" id="63683147"/>
    <dbReference type="HOGENOM" id="CLU_010743_3_0_1"/>
    <dbReference type="OMA" id="FKSRVCN"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CID_dom"/>
    </dbReference>
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        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="187"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CID" evidence="5">
        <location>
            <begin position="423"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="80812" checksum="B1E544D3347C0C8C" modified="2013-05-29" version="1">MSALRKPNLAMFNTSDDDEAAPPPQSKSKVDDAKIQHFTSGSVRKSKKDKEKEAAEAKAREEEERAKAAYAEFLDDFASGPVDKREGKGFVRAGQSGSAPPNARGRGPVKANMAWDEEKPEESAPAMGGARHYTKGRRAMDSFLEEIKRDQASREERLKRSGQAQSSSFTSSESRRGSRDVGDMETTNVFVANLPTGVTEQGLGTYFAKCGPVGSVKIMWPRHEDPPSVLGVPTGPRRQNSLSGFVCFMKRRDAEVAVSDLDGAEWNGSTLRVGWSKAVSVPSRAMFDLGPGIGAKRGRSRSPERQHHKSHTSRSKSRSPRRYDSGRDRDRGRERDRGRDKDWSPDRRRRDSRSRSPPRKRYRDDSRTPERSRERRRRSRSPEEYKRERTLELEQFDDDGANSIYSTDSAEESENENHRKGTLGKLALRRFESMLRGTTGKRGEIARLMSFALNHADAATEIARIILSSLLVDSTPVPRKVARLHVICDILHNSAASVPNAWKLRQEFESGLGQVFDHMETIHDSFPGRITAETFKKQITNVLDVWEDWIVFPPEKTQEYRRRLDGNVVQEVAEEEETVQEEVREEVQEKPRFKASSFRPAGEAEDVDGQVMEDVDGAPIEDVDGVPMDDVDGAPMDDVDGAPMDDVDGAPMDDVDGAPLEDVDGAPLEYVDEAPLDDVDGAPLEDVDGAPLEVDATHISPAVVIPPTSGPVAVDADEEEDMAIEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFW9</accession>
    <name>M5GFW9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_77001</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 15">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631407.1">
        <property type="nucleotide sequence ID" value="XM_040776242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFW9"/>
    <dbReference type="STRING" id="1858805.M5GFW9"/>
    <dbReference type="GeneID" id="63691304"/>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OMA" id="VIDANCT"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000008">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="17">
        <location>
            <begin position="50"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="18">
        <location>
            <begin position="249"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU04513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="450" mass="49878" checksum="6C34C91E68F5209A" modified="2013-05-29" version="1">MREVISIHVGQAGVQIGNACWELYTEEHGLTPDGRLKSDPNRKPDTMEGFSTFFSETSHGKYVPRSLFVDTEPGVVDEVRNGKYRALFHPENMVTGKEDAANNYARGHYTIGKEIIDLVLDRTRRLTEACVGLQGFFVFHSFGGGTGSGLGALLLERLATDYGKKSKLEFSVYPSPSLATAVVEPYNSVLTTHSTLEHSDCSFMVDNQALYDICRRSLSIPAPGYTNLNRLIAQVVSSVTASLRFSGSLNVDLNEFQTNLVPFPRIHFPLASYAPLISADKAGHERNSVSELTFACFEPQNQMVKCDPKDGKFMACCLLYRGDVTPKDVTNAISTIKTKRTVQFVDWCPTAFKLGICDEPPIVVPDGDLARVPRALTMLSNTTAISAAWSSLDHKFDLLYSKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVARDTEEAGEEEAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFZ4</accession>
    <name>M5GFZ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_47323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631487.1">
        <property type="nucleotide sequence ID" value="XM_040774750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFZ4"/>
    <dbReference type="STRING" id="1858805.M5GFZ4"/>
    <dbReference type="GeneID" id="63689812"/>
    <dbReference type="HOGENOM" id="CLU_004591_3_1_1"/>
    <dbReference type="OrthoDB" id="2506088at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="22352" checksum="F4795C039EA34CDC" modified="2013-05-29" version="1">MPSSTHYSWWTVSDSQPYWLHHSYPTQGLDPHESTLVELLHTFLLGICKYLWGHTVKILEKKPNTKAGHAQMDALSKDGLNIPLIPSAYIVQYKYSLISKHFCLLIQTMPFLIEDLVDGEVLEAWVMLGLAAVQLWWTDIQEPDLYLVHLILELVHAFVCIDPIKIMSKSKLHILHHIVQHIHCNRPALLFSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGC8</accession>
    <name>M5GGC8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632157.1">
        <property type="nucleotide sequence ID" value="XM_040767813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGC8"/>
    <dbReference type="GeneID" id="63682875"/>
    <dbReference type="HOGENOM" id="CLU_748069_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="370" mass="41069" checksum="565A194F02BAD3AB" modified="2013-05-29" version="1">MSLPTPDEYDRFARAARCILQAYRTCLALKIVHQEVHKSSTDVALDIKTLEEELAKYEKAYEVEVKKLLPFPISEQAPHDSDGEMPCEEDRDEQDDQEINDEPPMEVSDAPQLEQQPDVERAENGSAELGTDDLADWDKIPDERARAHMAQVDVIDDDSMMAVADIDQGNERMDSEDASVHTQQENATPGGRMPTFGSVKEVQVVTLQSDQSLDDNEESEDAEPSERKRVSFQETSDGDIQSVIEFEEHAQDDGTHRRRRVQDLADVRSRWMYIEETDDAENTTPEKTDVPDSALNMPQEEDRDVIIIGSGPSGDMAEGYAMDAPQLSVASGPTISSPAPSPPPSSAPSTTPRTWTDTHHVSEASKSPCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNM7</accession>
    <name>M5FNM7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_112734</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JH795933">
        <property type="protein sequence ID" value="EJT96468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623366.1">
        <property type="nucleotide sequence ID" value="XM_040769490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNM7"/>
    <dbReference type="STRING" id="1858805.M5FNM7"/>
    <dbReference type="GeneID" id="63684552"/>
    <dbReference type="HOGENOM" id="CLU_038704_1_1_1"/>
    <dbReference type="OMA" id="NLLLTWH"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="36915" checksum="8DC629DFC91B7173" modified="2013-05-29" version="1">MSAQPIRVLPVELSYTVLSSLPLPLPRRDFHDARLSILASAFSQSSTSDILHDTEDEHRRDISGVDERKFEEVFNERSDVRPGLYEGGMKTWEGAVDLVNYLSDNERRTAALSQGSILEIGSGTALPTLFLLAKIFQSEGKEDAHERAVFLQDYNLPVLELMTFPNILLTWYLYSPSAAMYRFPHPPVSPGQPISLRLSSDLLSSFRASLTKLKLSLRFWAGDWDMLDVGGRVGLVLTSETIYRPEAVPSLARCIRRALEQPASSGSRVTKSGQETLDEPSVCLLAAKDVYFGVGGSVAEFEQVAQRLGMVGRRVWEVTEGSGRCILEMMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNR1</accession>
    <name>M5FNR1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624723.1">
        <property type="nucleotide sequence ID" value="XM_040773850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNR1"/>
    <dbReference type="GeneID" id="63688912"/>
    <dbReference type="HOGENOM" id="CLU_959853_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="310" mass="32524" checksum="DF41B3132FDFC629" modified="2013-05-29" version="1">MTDSHPSPALLLQVAYAKQKGLGFGAMVLSWLQQHPELVANGVARGTHAHVDALGHCTCNTLTPDTGVPIQSTSYTQDIMEPVSIPATVTVALQAPADHADRGHRTCITEESKTSPRLWGSTGACLRGPVSNSLSADSASNSSVVPSPFPQTTISHSDHTAAAVPGSVVVTASTECPAHVPSTGTVKHELDKASADELSPAYHPSSYPSISSSLLDAHPASNDEAVPLYCHHEVLPPRYTPPRKRLKLPPNLSRSSSPTPSTSSSSPPSPRLVALDRATLQAVAEAQAAREVSAELVRRNRLVGGRLVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNR4</accession>
    <name>M5FNR4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_91301</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624733.1">
        <property type="nucleotide sequence ID" value="XM_040777003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNR4"/>
    <dbReference type="STRING" id="1858805.M5FNR4"/>
    <dbReference type="GeneID" id="63692065"/>
    <dbReference type="HOGENOM" id="CLU_009646_8_2_1"/>
    <dbReference type="OMA" id="MKWTHIA"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="45"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="236"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="442" mass="47719" checksum="8B173A99E2B805F3" modified="2013-05-29" version="1">MRSQRLSSVSYATLSRRPSVRHRASWGVLKSQDEAPIAEAPGGGTSTFGQSLFNCIAILLGVGVLSESVAFTYAAWIGGFVLLGTYGILTYYTAKILVRIMALDVRINSYADIARVAFGPRSIWLTISMFCLELFTLSVILVLLFSDTLHELVLSISSDMWKIIGLAFVLPTCFLPLNLLAFTSILGILSIVLLVSTVLINGFSITSTPGSLLRPAPTSLLPDWPRLPIAFGLLMDLCNPERFDSMITWAYVIATVLYGVIASAGYLMFGNAVSDEVSKDLVNTPGYPRWLNIVMAVGLVINPLSKYALCTRPLSTTIESLLGIGNMSVGADPHTSAADSSDPKSSGHKRLLTKQTLYIVLTRVVLSLVVVLTAILIPSFSIVMSFLGAFSAFLLCVIGPVCAKCAVEGRWKWYDVIILVVASSMAISGTIMGFWTSCLNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP12</accession>
    <name>M5FP12_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623601.1">
        <property type="nucleotide sequence ID" value="XM_040769435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP12"/>
    <dbReference type="STRING" id="1858805.M5FP12"/>
    <dbReference type="GeneID" id="63684497"/>
    <dbReference type="HOGENOM" id="CLU_470922_0_0_1"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="579" mass="64955" checksum="1DFFC5D8C191833B" modified="2013-05-29" version="1">MSSLKRKRSTSPSGSAAAAAPPPPPPPQSLMMSSEYARMTDNSSAHDDLERDRIAMLNDKVFTALSRPPEAYGNIDALAVLLQRIVKNSPSLNRNYLDVENATRLIEKHPDLEVLLREAVKTRNCEPVIASQLATAAAWKGELRGTSHKLLLKILDEMNSKRGRGVYTNYVAMVQSSGMSESRMMYECSKLCLGPGFNLLHDNAANGGAYPKPNKEVRDYLLLNVRAVAPRNLPSEYMLRYTALFAALFQEMKNELDTVKFKESATNLTREDVGWQWHEHLQMRSTESSDQSRRNDLYKRVVKLNLKALLGDNYESVVQNSRADNAVNSATFDETFHNSFMRFTHFVRSSHDFHPTSEHAWIMFARGAAVITSHNYPKLDVWVPVLQWEEKLNENVMTAMFLEIQNRASEVTVSFNADEEGFFVSEDGANKPRSYITLVMQLDLYRPTNNRRTINAQTSVPSTLSNVPVGQGPSRMMHGRGRHRFSIVVKGCSPSVYGVVEEQNKDAFKSLLEVRDVISEHPRPDARDAILQLKPFFGPKKASLGWVEDAKYDDDVNAGEALDPDVVLVGQGAVSQLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP75</accession>
    <name>M5FP75_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625188.1">
        <property type="nucleotide sequence ID" value="XM_040767610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP75"/>
    <dbReference type="GeneID" id="63682672"/>
    <dbReference type="HOGENOM" id="CLU_027355_0_0_1"/>
    <dbReference type="OMA" id="KWWNDTT"/>
    <dbReference type="OrthoDB" id="3363836at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="574" mass="60473" checksum="6426C402021B6613" modified="2013-05-29" version="1">MGLDIIHVPRTAGHHLKRVVKRSDCASGGLYVSPTAGQSVSPSSNVNITWDNTCLGSPTPPLVDIYVYAPASATPLIHVWGNVPASTGTYSDMINPSWWNATAGSTESLQLLIVGAGQPSWMTSSPSGPIFTVATPSNYNASATAAAAATSGGSSSSSNNSGSSSSGNNSIYESVTQLLEKVFPKGAIAAAVLIPIIVLVAAAIIYIKWSRKKEAKKRERFSQAIDKRMSVISTDWRPSTTAGARASIAVGAHRGSLATSVYLPRPSSTFATEGGQAGLGAYNGEMSEKAIPRPSFQTQTSLGVPSSQTTRVSRISFAPTVHPRISMAAKDVLGTSDEEDEGAMSPTQLQGPTLLADDDVARASMDENFRAEVLQMPAMTMMRTGRQSIHVPQTVDMGYEQLTGDYRSPSPTSAGTVVPSVSTTMSPLTGFFPASSPSPTTTMSPDDQLRAYAARRAASPLPPQPAAVGSHPGMRVLYDPSAHQQAAQMPNMATLLSPTQPLTISQNSSNRLSVMTTNPNRLSVATNNPFRQSTISQGESVGSRYSHAEVNHDVEAHEHVLVEEEEPIPHGSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPN6</accession>
    <name>M5FPN6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_25626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623437.1">
        <property type="nucleotide sequence ID" value="XM_040774244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPN6"/>
    <dbReference type="STRING" id="1858805.M5FPN6"/>
    <dbReference type="GeneID" id="63689306"/>
    <dbReference type="HOGENOM" id="CLU_022195_0_2_1"/>
    <dbReference type="OMA" id="FAFARIM"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067173" evidence="9">
        <location>
            <begin position="21"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="56261" checksum="971ED9E70F53067E" modified="2013-05-29" version="1">MALQWDVILAFVLIVSLISAVQSRSRKSSAPVLTSDWFFGYPTALKMFTQYRPMLVEGYAKFNKHAFQVPGIKGWIVFVGRELYDDVRKARDDSLSMPEQVKDTVALEYTIDRAVALDPWHNSVVRKQMTQALGAKFPEIYDEITSAFQDELKLSGKEWKPVYAHDLIIHIVCRASNRLFVGLPLCRDPVYTQISRDFSGTVMFSGFLINLFPTFLKPLVGRWITAAPRARKGFEKFLVPMIKDRWRKEQEMGELWEKDKPSDLLQWVMDASKEHDSTPEDITNRLLGVNFAATHTTSLSFTHVVYWLAARPECASILREDVDEAVAKHGWTKTALGEMHKIDSFIKESLRVTGIGATAMGRKAMKDLTLSDGTFVPKGASVVMNLWGIHHDPTIFPKPLEFDPLRYSRRIEAGESEAGNSLATASGEFLFWGGGSHVCAGRHFASQEMKTMLAVIVSLYEVKFEGLADGVRPKDRWMAYSCIPDMKQRVMFRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPP3</accession>
    <name>M5FPP3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624111.1">
        <property type="nucleotide sequence ID" value="XM_040769357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPP3"/>
    <dbReference type="GeneID" id="63684419"/>
    <dbReference type="HOGENOM" id="CLU_2096801_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="116" mass="12694" checksum="4C01F1A86AB007D2" modified="2013-05-29" version="1">MRLTHALLIAFIAFIAFIAFIAFTAFTAFAYPVEPSSDRSQGKPSPGRGWRTAIHRMYPTGHPSSQLAREAEAAKPEAEAAKRESPAQKQLKQARNDLVEEIKSDSEADQFSASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQJ1</accession>
    <name>M5FQJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gti1/Pac2 family-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623907.1">
        <property type="nucleotide sequence ID" value="XM_040774155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQJ1"/>
    <dbReference type="GeneID" id="63689217"/>
    <dbReference type="HOGENOM" id="CLU_520762_0_0_1"/>
    <dbReference type="OrthoDB" id="3349072at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="56517" checksum="6DB93FB9A6DE82C2" modified="2013-05-29" version="1">MDSPLSAGPYRPIHGAYVRDKTDALILCQAAHDGLVQQASQKISIQQRKQLATSGSLFVFEKSTAEMERWTDGRGWSRSRQLPDKFFVYFEEYTNSNNMNSAGLSNEETTTPKRTKRSDPSDLIGNLVGPLRYLSGFSTQVLIKKTITLKFPGKEWHVVSYFTVDDVLSGKLPAVSDSSLFQGSLSHVAHASHSMGPMIPSPPPSMPPRQGRMRSSTWSNGSEPAAGLMHQQVVQDQHTTHRGLQSRVIAPPRLESHPGYNTMNGIIPVNGNLGSGPTSPVRRTGPSLTPLDTSLPMSPNRRASAPTAPIGFLTHSRGHSGASSPNSATFSYSPMPFQFPTLCTPPFGTIAQHSLGEHGAFPVASRGIPPMTLPSPQQSIAYQSPPSSGRMNMAPWGFPETHAPLSPSACFDFEAYASSLTPDKGSSQSSPTMSDLPVGGSFQGAATSSSTVIDPFLDVGHWGFENDGARDCVHEQITPKAFEHGPISFDGGLMLSNDADVTMDFQMQQWIDTNCHTQWPAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR12</accession>
    <name>M5FR12_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_91086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624941.1">
        <property type="nucleotide sequence ID" value="XM_040776993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR12"/>
    <dbReference type="STRING" id="1858805.M5FR12"/>
    <dbReference type="ESTHER" id="dacsp-m5fr12">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63692055"/>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OMA" id="PRTHATN"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140960" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="28"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="553" mass="60072" checksum="878752237D3D5385" modified="2013-05-29" version="1">MAITTLLYIAALAAAALAWTTPPTATVINGTYQGINADEFGQQFFLGMPFAQQPVGDLRLRAPLSLNESWTGTRSASNYSAICPGFPIASGADDDKGYELSEACLTANIIRPNTVSASSSGGGFSMGGSADHRYNGSWIVQRSMEMGSPIIFASFNYRVHAFGFLGGAEVHAAGLENLGLFDQRLALQWIQENVATFGGDPTKVTVMGESAGAMSIANHLTAYGGRNDGLFRGAIMESGSPTTENYARIQQLEPFYQSVLVKARCANATDTLNCLRGVLYDTYRAATNGTNWQPVIDANGSHQWQPIIDGDFLPEYPTEMLQQGEYVKVPLLMGSNTDEGTSFAVYGIENTEQLAAAMSTNYPRLSNASIERVIDLYPNDPAIGCPYGSGDGLLPSGYLDKQSAAIFGDMLMVSGMYGVCGANRELSDTQPVWKYRFNQVPINYTMTPSSVMHYVEVAYVYSNQLAVDVNPLGTRPNDLSLANLMTSMWISFVNNLDPNYSQVEGAPFWPSYSSSPKNLVFQNNWLGSSYVEFDNWRQEGIAFINSLGADMQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRJ1</accession>
    <name>M5FRJ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_118617</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625206.1">
        <property type="nucleotide sequence ID" value="XM_040770622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRJ1"/>
    <dbReference type="STRING" id="1858805.M5FRJ1"/>
    <dbReference type="GeneID" id="63685684"/>
    <dbReference type="HOGENOM" id="CLU_2190198_0_0_1"/>
    <dbReference type="OMA" id="RAKWWEV"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="132" mass="14073" checksum="1B3B19C167C8245A" modified="2013-05-29" version="1">MSGFAHDNIRTLEVDVCSSESIEAAVRRIIEGCGRIDIVVSNAGVGAFGPILDVSVDKARAAFDTNYFGSHRLAQAVLPHMFQRRSGKFVLVGSIAGLIPVPWNGTYASSKAALHTLADVLSTNAPRLTFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRY5</accession>
    <name>M5FRY5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626923.1">
        <property type="nucleotide sequence ID" value="XM_040770422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRY5"/>
    <dbReference type="STRING" id="1858805.M5FRY5"/>
    <dbReference type="GeneID" id="63685484"/>
    <dbReference type="HOGENOM" id="CLU_118210_0_0_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22302" checksum="70825FE383295EAD" modified="2013-05-29" version="1">MTVKSPWYLLPLSKANILVSTGTFLYVILTRSFHAAYFGIGTLLCSLSGTPPPPPALSLPVTANPHYALAKALKRLLRHPRPPGSPRPLTYGMPSTHTSAMAFQSLYLTLSSLFLSFTALSFLPLPLLPTPASPPEWLRLALPGLYVPYALAVAASRITMGHHTLPQVLGGALWGVVFAAGWWALWPWAKELGEKVLPWLGGRVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSG9</accession>
    <name>M5FSG9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625716.1">
        <property type="nucleotide sequence ID" value="XM_040769108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSG9"/>
    <dbReference type="GeneID" id="63684170"/>
    <dbReference type="HOGENOM" id="CLU_1337479_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="205" mass="22813" checksum="FEDB3F03CBA05F78" modified="2013-05-29" version="1">MQPFMINHGRLDYENAPSKAAQSLQRRSHNTLTTITPALPSYLKRSTSSLLLPLHFITMPTLKFLLAVLSFSVLATSLPVHTNGSRRLALRNADLEERSTAFGLKYPKTSWLAPLTTLTPTLKLGNMRTSAGGVTIRKWIDTQHTEGQSFTCPACKSPTTTLITTVKKKDSMSSARKTMPKKAKGKRDLEDVESKSEFEMRDFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSJ5</accession>
    <name>M5FSJ5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N2227-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_68588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627323.1">
        <property type="nucleotide sequence ID" value="XM_040775877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSJ5"/>
    <dbReference type="STRING" id="1858805.M5FSJ5"/>
    <dbReference type="GeneID" id="63690939"/>
    <dbReference type="HOGENOM" id="CLU_030612_2_1_1"/>
    <dbReference type="OMA" id="YVTQFWT"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF13">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="421" mass="47241" checksum="DCC3DEB4A3B6AB51" modified="2013-05-29" version="1">MRSSLYLTRCLPLVLTTFLFCYFALQCSSNLLQLHPILSRLSERADALHEALISPLASDRHPPLRPLVGESNASDELAVKTIKHLSHLPPGLANTINSYENYHHLALDVIFKKESRYLRQSPTKIALSQKLGYDKHFDAARKGIAVNAKFATEVARHARDVYKVGESEIGEEEDADYHLVDLSFGHLSRDWSAQGKPERDAVFPPVLEALSHFFGPQANGLSSGGKRVLVPGSGMGRLARFDVTANELDYGSIVTYRLLVNSSLTPSLHTHSLHPFSTKWTHQALPNARFSRITFPDHRPNVDVKLVEGDFLDVFEHETGVFDAVVTLFFIDMSQSVIDFLANIHRLLKPRGLWVNLGPLKWGTHADLQLSVLEVLELAELLGFHVDHTSRKSIDSVYAAQPDTLLKFTYVTQFWTATKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSM0</accession>
    <name>M5FSM0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625816.1">
        <property type="nucleotide sequence ID" value="XM_040773513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSM0"/>
    <dbReference type="STRING" id="1858805.M5FSM0"/>
    <dbReference type="GeneID" id="63688575"/>
    <dbReference type="HOGENOM" id="CLU_011846_0_0_1"/>
    <dbReference type="OMA" id="RPHAVHM"/>
    <dbReference type="OrthoDB" id="1918363at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="875" mass="99015" checksum="03DA7963D5DB701F" modified="2013-05-29" version="1">MATPDLTALLASSRNLAAHLEQQELPHLTLGLDQIENQSRKLVSRTGGPGAAERANYLLAQARVNAPQLQNLATSLNPAFTFAPLQPVRDTDIASHLRHAHEQAILSTIEETRRDTAQSFWRSMEEKIGRDWEEKKKRVIEELATGDERRTLESSGTSWGNRSLAQSQSFAASIGPGLSQSQIAGPSQPSLGMPVHSRMMVYDRVVSDLNRARLQGTPFPIIHALIDATERLPPEPKRDQIVSTFSLLSSILGEADPRSASYQTAPLAERAYSQAYLSPASTDALAKNLRRRILAGSMKWLEDLYTQHVDITLQNNPVEAALGASPSASNKLRAFLAMRYYEAGRWQSNLELVKGQPLWAKIYFLLRCGHPEEALAEAEKQDAALNKFDKFFLPCLREWVANDDRSVSKQLRDRLLTSYNTHIRHAPTIDPFKHALFKLIARAEPSRRNVPHVTETTEDWLWFQLAMADEPKEGLPTNDGLKEVAATIVKFGEKSFDKDGRRPWLWVRILLSCGEFERAVASMHEKSNMSVEAVHIATALAYYGVFRVPKSSQPSESSLLLPGDSSSSFRFDTLIQRYIRHFTRIDPKEALQYVYLITLSSDAPGDTGKEQVAYAHSLCRQIAFESPNYEELLGGRRRDGLSFPGAIEQNMKLLHLADAKQYHQSIVLNLALQYHSEKRLIDAVKLYNLAGEYNDVMKLLIQAIGDTLFESPEVESEAGHIRSTAREMWETYYTTPDIRSRVQDALLRTCQKLLKIREGFEDIHYGRQELGLEKLDQTDLLPFKTTVYDMHRKAEEVKREDPAVVRNLPEIIKQTMEALWTLYREAKKRTGEQGFQQRLMNLREKAKRLNMFATSLGLAGMDFPTLNTLESYMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSQ7</accession>
    <name>M5FSQ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="4">2.6.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-aminobenzoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">p-aminobenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24078</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11672"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58406"/>
            <dbReference type="EC" id="2.6.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="4"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625871.1">
        <property type="nucleotide sequence ID" value="XM_040773534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSQ7"/>
    <dbReference type="STRING" id="1858805.M5FSQ7"/>
    <dbReference type="GeneID" id="63688596"/>
    <dbReference type="HOGENOM" id="CLU_006493_0_2_1"/>
    <dbReference type="OMA" id="TQWHPES"/>
    <dbReference type="OrthoDB" id="64220at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008153">
        <property type="term" value="P:4-aminobenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF18">
        <property type="entry name" value="AMINODEOXYCHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="269"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="12">
        <location>
            <begin position="531"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="11">
        <location>
            <begin position="745"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1033" mass="114498" checksum="02EFB275D6727358" modified="2013-05-29" version="1">MSTCNEIAQSHSNSNLSRPRALTTILYEPGDGFYLLQRHVERLRAAHIYLGSTSPGFIDELSWSVGSGLMQELWGVVRSTGETFPQRVRVEVTHDCRIIATSRIMVTGPLTTLTVCLDTRPTVPRHAEHKTTDRANYDSARGRVDACLDLEGVRMPFDVLLWNPAGFVTETSISNVAVEMHYDQSSSPRFVTPRVTSGLIAGVMRQELLSVGFLEEGDIRIEDALCAAQEGRRIIAFNALRKVFEVKIITALPQPSLFRELPFPMGVGVIIDCYDSYTNNLLPCLNTANLPPQEFERYLESSVAVIRLHTFPWPVFRDHVLPHLEWVIISPGPGRPDNTRDFGFCAELLRTSEVPVLGVCLGHQGIASAHGGSIISSGDVVHGRTVLVHNNNVGVFANVPSAQMVRYNSLCVDPENIPEDIHVTAWARSSDGATIEIMGLQHRHKPQYGVQFHLESTCSDHDTARRIMQSFALVVAQHSKHRAASSTKLPDICRTTSYIDFSKLRSVSPCIDTQIKQPLRVLSQQLVVQATPVEMCSYLVEACQEDLGINVFWLDSARSSPNDPLSRYSYLGTSNRSIQYEPGTALLHKGMEDVSLPLRPGQSFWSWLDTLQRVIHENSANDAIAAPNFQCGLVGYLSYEMGKESLDGYESSTRNTAYSGPLAQFMLIDQVLAFDHHTGVWHAMGLIRGSADSRMDALSELLPCQFGITELEFYSWIRTLEIPQPFPSSTRKSALPSLFDFNYTHDSYMDSIRRLIQKIGEGESYEMNLTGQFTGLLHDTPSLKDVFALYGDIRTKNPACYSALLCFTRTRTHVLSTSPELFIELSGVGGTEALMKPIKGTLRRTPCRCAPCTDPDGCEVNRALQDAQRLAAFEADPKERAENLMIVDLIRADLQNFCHTSSVTVKKLMDVEASETVYSLVTSVEGKLVPDVGPVEAICRTFPPGSMTGAPKLRSVELLEDLEGHQPRGIYSGCLGYISVNNRASFNVVIRTLVIQDCKASVGAGGAITWLSDPDSEWDELFLKARSVLQDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSX0</accession>
    <name>M5FSX0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627513.1">
        <property type="nucleotide sequence ID" value="XM_040770318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSX0"/>
    <dbReference type="STRING" id="1858805.M5FSX0"/>
    <dbReference type="GeneID" id="63685380"/>
    <dbReference type="HOGENOM" id="CLU_012494_6_2_1"/>
    <dbReference type="OMA" id="CPPDAFF"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="95"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="334" mass="36036" checksum="01049B8141B1AD56" modified="2013-05-29" version="1">MSYTSKHGPIHPSVLPLCDPAYVEYYNSAILGGIALDYTAPFDPSIRTVPLLSGGAKPLECVAEEVQIGECNVRVLTPPAEGGGKQVKQGGWPVVIYFHGGGWVLGSIDSEISIATQLCRRVPCVVVSVNYRLAPEHPYPAAVDDAWSVLLWVRAHAQEYNINPSLLAVGGASCGGQLAAVISHMAVLSSPPIPIALQLLTVPCTDLDPAAPYPSRELFALGPALPAARMNWFYNLFNAPPKEWKASPILAPAEHWDRLPPAFVVVGGLDFLRDEGVEYARLMNERGAKAELKVFEGVPHHFPSLDGVLEQGKEYVDDAVDRVAKAFKEAEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTR2</accession>
    <name>M5FTR2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625722.1">
        <property type="nucleotide sequence ID" value="XM_040773657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTR2"/>
    <dbReference type="GeneID" id="63688719"/>
    <dbReference type="HOGENOM" id="CLU_2694457_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="7859" checksum="D2A752E75CC504AE" modified="2013-05-29" version="1" fragment="single">MFALYKLQQAPWKPSAPSQVYVTESGLMENTGGTPEKGIAAESSIGSADRLALRASSAMVDSYKRLGTRGGRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTV5</accession>
    <name>M5FTV5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_80567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627993.1">
        <property type="nucleotide sequence ID" value="XM_040776453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTV5"/>
    <dbReference type="STRING" id="1858805.M5FTV5"/>
    <dbReference type="GeneID" id="63691515"/>
    <dbReference type="HOGENOM" id="CLU_000288_7_18_1"/>
    <dbReference type="OMA" id="LMVDRYF"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="220" mass="24816" checksum="6CF27C2E9B27246F" modified="2013-05-29" version="1">MSIWSELRHPNILPFLGLARLDELGPCFVSPWMMHGDVLSYLKEYPTMDRVRIIRGVIQGITYLHTQKRPVIHGDIKGLNILISSEGFPVLCDFGLSILLDPDVDRATTTTAALGSQRYMAPERLLPRRYNLSMHQSRTPAADMFSFAITAFEILTSIIPFVGISGFNAGMEIVNGRRPDIPEVYYNNPAHKNLIESITGCWCERREERLTAVQVLELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUA6</accession>
    <name>M5FUA6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase III subunit RPC6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_52685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628193.1">
        <property type="nucleotide sequence ID" value="XM_040775122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUA6"/>
    <dbReference type="STRING" id="1858805.M5FUA6"/>
    <dbReference type="GeneID" id="63690184"/>
    <dbReference type="HOGENOM" id="CLU_033661_3_0_1"/>
    <dbReference type="OMA" id="PVNPREC"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="251"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="458"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56972" checksum="93FC279532B1E886" modified="2013-05-29" version="1">MPPKSDPSGTDTLSSVEQVLYKAVVDADVLYQREVEASCPGYPVIELQQAINALLRKSLLKMMKDSKGKPCFKAVNAKDARLLGALQGDESMVYTHIRNSGTEGIWTKSLKAKTNLHATVINRCLKQLEQRQLVKSVKNVKFPTRKTYMLFNLKPSVELTGGPWFNDNELDVGFIEGLLQAVYTFIEKKVNTQTFVGDDYQVWPTSRTDKYPTLADVRRFVHGSGLTEVKLEDEHVKSLLDVLVYDGKIESLPGSGGKGWEEKESDEDRERERSREKRKKRKRAASESDEESEDDRARRKKRSKRRSRSDDEDEKDEKHDSDDEHSHHRSGNMKRKRSSRSDESESEEDDDGSDQPRSRKKRRASLSPTRSLSPVTFRDASPLSLSFSGSVFRAVRRETYGSGLSEIPCGLCEVFDFCAPKGPVNARDCQYYDDWLMPDKIETRGKGKGLARQEMVQEGGEVEVAEEGEEGTWDESGYAEEAYDGDGGGMEIGYEEETFEEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUN0</accession>
    <name>M5FUN0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623869.1">
        <property type="nucleotide sequence ID" value="XM_040774149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUN0"/>
    <dbReference type="GeneID" id="63689211"/>
    <dbReference type="HOGENOM" id="CLU_3050277_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="6059" checksum="F4B0BDEB2147D4A6" modified="2013-05-29" version="1">MTSIGDRLSLGSPILSLIVYFSRTGKRPYEKDTPQEKNYRLVLAPLVGCVYNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV70</accession>
    <name>M5FV70_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_52711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628573.1">
        <property type="nucleotide sequence ID" value="XM_040775124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV70"/>
    <dbReference type="STRING" id="1858805.M5FV70"/>
    <dbReference type="GeneID" id="63690186"/>
    <dbReference type="HOGENOM" id="CLU_020880_2_2_1"/>
    <dbReference type="OMA" id="DVYTMQQ"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF42">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="59448" checksum="853A84597ACD6206" modified="2013-05-29" version="1">MQAEDYQPERVVFRPAAPYAGSTLAPARPIIHPSNAITSLFPAKNGPAGPTPTGAEAGMIQTASSYPMKDHPDILMGPKPASDDFDIFKHWGNLSPWYSVPSFGLDSSPLVPDGCRVTMLNILHRHGARYPTSSGEGVGPAGFATRLHNALTSGKTWSAGGDLDFLNDWVWMLGADVLTPFGREQMYKLGVDLRIKYGFLLNNFTVSQTLPVFRTESQDRMRSSSENFALGFFGERAKDQYLASITVEASGFNNTLSPYYTCHNSFDWNKSYRQTPYMKIWLPTYLKDTLPRIQSMLEGFELSYDDIFTMQTICAYETVALGYSAFCGLFTQEEWEGFEYAWDIYFWYDSGWGSPVARGLGLGYVKELVARLTNTPIAVHDSTTNSTLDDNPITFPLGSSLYVDATHETVVLNILTALNLSSFAAAGPPPADHIPEKRSFIASQVVPFGTNVQFQVLSCAATPDPQIRIILNDGVVPLEGLGDCPYQQDGMCAVHTFVAAEQKILHEHDWSWSCTGNWTIPPGMDWQTTTGDCPPRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVA2</accession>
    <name>M5FVA2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="10">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_54516</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="10"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627086.1">
        <property type="nucleotide sequence ID" value="XM_040775267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVA2"/>
    <dbReference type="STRING" id="1858805.M5FVA2"/>
    <dbReference type="GeneID" id="63690329"/>
    <dbReference type="HOGENOM" id="CLU_003364_1_1_1"/>
    <dbReference type="OMA" id="WMWEWHT"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000041">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="12">
        <location>
            <begin position="21"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="919"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="928"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="988" mass="111469" checksum="D61F53606875E3EE" modified="2013-05-29" version="1">MREYLGQVRVGRASLQDDPTARQRLMEESAYMVAAQRWRHQAEEMTHHNVAGWNTQHMKLKKWMWNWYQALKERLDNEIPTLEEEEKLAQRRKPTDGDAIGPFLRLLSTEKMATMTISELLRYGTSDGGVRTARTAITLGRVVEQEYNAEVALAQRSRGPDPVVLTSEGSLTELAAIRQQARDSEDFTMAIPPDWTQVIRGRVGGFLLNAVIDVATITRRGIRPSTGEEVSEEQPAFAHCYEFLHGRKIGLIKFNPELTEQLSSEPIKDALHPRQLPMLIPPRPWIDVERGAYMYSRTSVMRYKDSLEQSSFLRSASSAGHLESMYAALDVLGSTPWTINRPIFDVVIAVWNSGKQFAKIPPAGLEGEDPVKPDNYETDPKAKRDFVRAMSTSIQKRHENHSMRCDTNYKLEIARAFLGERFYFPHNVDFRGRAYPVPPNLNHMGDDLCRGLLTFADKKALGERGLRWLKIHAANKFGYDKASFEERVTWTMEHLDEIYDSAKKPLDGQRWWLKADDPWQFLASCIELHNALESPNPAEFESSLPVHQDGTCNGLQHYAALGGDGQGARQVNLDVGDRPADVYTFVANMVEKRLDEAAAKGDEKAKWLQGRIARKVVKQTVMTTVYGVTFVGARDQIRKQIEALPGVSISEQESYAMAVYVARLTLSCIGDLFGGAKSIQLWLNKVCALITKSIPPERIDLLLRDKEYAGEVRNAPMKRTYTSLVKEQMTSMIWTTPLGMPVVQPYRKQAKKQIYTSLQSLFIADPNLPMEVSSRKQASAFPPNFIHSLDATHMMLTALGCRDKQLTFASVHDSYWTHAASIDEMSATIRDTFVKLHSADILGNLLLEIQQRYKDYKVPVSLLTTMHLTRPKPTMAEAEEEGAEEDADDSPGNCVALNVARISKEDLARMTSSEEIDLDIGKSGASSDEADAEAEVEENGTSKKRKYATRKLKPLKTRFVNLIDIIPPVPSKGEFDIQKIKDSLYFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVG1</accession>
    <name>M5FVG1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_94814</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
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    </dbReference>
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    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Winged helix' DNA-binding domain"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51939">
        <property type="entry name" value="XRRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="7">
        <location>
            <begin position="70"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="174"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="XRRM" evidence="8">
        <location>
            <begin position="344"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="61892" checksum="4414EA12ECB0AA72" modified="2013-05-29" version="1">MSTEAAPEALKVEAPVAEAPAPEAVPEIKSEEDGPAAAPEVEPEAKTDAAPDVKLEDTAVPSTFVKKVEDMTEEEVKAKILQQVEFYFSEANLPFDKFLFTLSYKDNPEHWVPVGTIASFKRMREYTAAKGTAYVADALKPSTLLELSESGEKVRRKVALENLESRQSHDAFARSIYAKGFGEEAKGLQEELEAFFSQFGKFNVVRMRRDKETKVFKGSVFVEWVDMITASKFLMQEPKPRWKGTELTTMSKKAYCDMKIAEKGIDVTKDPLKRGGRGASVAEGAEGEQKRRADFSGWKLIYQQKKEQKAKVQAEKPDIYIEMDGEKIKLNKDGTVDPAEIEGKYKKGALVAFEGVEGNVPFVEIKDALKDTWSRTYVDYQRGSKMGLVYLGSDSGTSTEQPTQPITEEQMNIVREKMKTIGGKPVTWRHATDEEEKKYYVNRATVMAEKAYRPSHNQHGRGGGGGRGGRGGRGRQNGRGGGHQDRGKGAGSPVKKEASGRPDAVPVIKSALPVPAARLTEPASAVKMDVDAAENGLKRKREKDAGADGSEAKKVKVEEAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW70</accession>
    <name>M5FW70_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_97049</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624519.1">
        <property type="nucleotide sequence ID" value="XM_040777419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW70"/>
    <dbReference type="STRING" id="1858805.M5FW70"/>
    <dbReference type="GeneID" id="63692481"/>
    <dbReference type="HOGENOM" id="CLU_086803_0_0_1"/>
    <dbReference type="OMA" id="NELMLHS"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000013">
        <property type="entry name" value="Coatomer subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="14">
        <location>
            <begin position="51"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="25628" checksum="F50A53FD2F7F1D31" modified="2013-05-29" version="1">MKKALTAQHISPKRYSPGGGKRARDEVPTWTATVPYTVNKSQMANLTLYSVSAALILDTDGNRILAKYYKPPHGGLPTGTRSLHNLKEQRAFEKGLFDKTKKAGGDVILYDTYLVTYRHSLDLIFYFLALPSENELMVSTGLQTFFDATQLLLRHSVEKRTLLENLDLVLLGLDETVDDGIILETDPATIAGRVSRPKADTTDIVLNEQTLLYAYNRVKEGVQQRISAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW86</accession>
    <name>M5FW86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Snare protein SED5/Syntaxin 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_23477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626837.1">
        <property type="nucleotide sequence ID" value="XM_040773257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW86"/>
    <dbReference type="STRING" id="1858805.M5FW86"/>
    <dbReference type="GeneID" id="63688319"/>
    <dbReference type="HOGENOM" id="CLU_044998_0_1_1"/>
    <dbReference type="OMA" id="EHNHNVV"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000007">
        <property type="entry name" value="ER-golgi SNARE complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021538">
        <property type="entry name" value="Syntaxin-5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11416">
        <property type="entry name" value="Syntaxin-5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="231"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="315" mass="35167" checksum="DC0F932ABA65EC0A" modified="2013-05-29" version="1">MPVQDRTNEFRACVESIRNRSAIVPRAEQKQRLLANGRGKEKSEFARMAAGIGNDISSTTLKLNKLAQLAKRKTLFDDRPVEISELTYIIKQDIAHLNKQIAQLQAYVKAQRTASGKNVGKQIEEHNSNVVVLLQTKLANTSQTFAEVLETRTQNMKASKDRTEQFMYSASSAANQPPPQNSLLFNQQQDGMPSKGKARETNGDVLALDMAAAEEGHGSDFMQMQLLEQQDNYIQSRSTAIESIESTMAELGQIFVQLSRMVAEQGETVQRIDADTTDIATNVSAAQRELLKYYTSISSNRWLMLKIFGVLIVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWW9</accession>
    <name>M5FWW9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_67673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627811.1">
        <property type="nucleotide sequence ID" value="XM_040775855.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FWW9"/>
    <dbReference type="GeneID" id="63690917"/>
    <dbReference type="HOGENOM" id="CLU_001999_2_0_1"/>
    <dbReference type="OMA" id="PPCVDEN"/>
    <dbReference type="OrthoDB" id="1043025at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06626">
        <property type="entry name" value="STKc_MEKK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="917"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1074"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1259"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1074"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="946"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1286" mass="146071" checksum="BF38D0DA12368921" modified="2013-05-29" version="1">MLASVLEGDVLRMEKTRIASTSDEGRDEAKRRTLDIWLGLRARLRGRTEDEERKRLEERRMRTVQPAIDEILTYRVSTAPGMPSAFDQTVALLDRLDMAQSLYPDLKSMHGEYPASDHSDFLHRVDALNAYVRMVVSLRWRIQGIQKWTGSETMDVWQRHTSQEQPVRRSFSPNGPAGHMLGPGGELQDESSFVERVLKEDSLQKTLERATLVTSHWVVDNARETILSYGLLYRTIGLPGVEPELVSLIAFPTKLMEATLRVRLDSGKKVNEPSILVVDQMLDDFALSIALACTIKQEYEEFLRQDEAGLWVLPSCISEAYDEVLLEALRFLFKLIHWKLKTASRIYFKEVDVLEAQWPLFTAVSLVTEGGSLLVAEHVCSVTNKLMARVVNLFEAQLSLPVYKPALDSRSRQSPRNHPLRPRLERANAVPVMKERERPMGEDQILDWYNTVLDSVRLRYRKLQRFGRVLGQRFTNAAEYSIAHLPVDRFINALVGTGHLLVYCENYEEDGIYIIADPSLRNRPYLIHDILQRTFQPVEVGPGKQQVTDGSGLDEEDEEGASTESYLLLITPGERFVWTGDVMVFDTQKQVFELAEKRVRLVADGPQLRLARAKDRFGEIMRSIRPENLLSPTSDGSESVNGDAFEGASDFCIIPLQAHHPRVDRQLRRITRSTNRLAEAITKSVHRVSETLEGVEHRQELLANWYAFAAENGQQAQKHMDHGSWQKFNRELMKLAIAYVSFICDECDPSDRRTFRWAVNALEFATLRTRGSNILNLPESDFNLLRSKVATCMTLLISHFDILGARSNLEASQREQERLSALRQRQEEAHAKRDVDELVAQPSMQYDPLAVSNWGEDRSIRLNRDESWLRQLQELDLRRAKLEAEQRITGKVINEERPEDKTLMFLASSSSNIAMRWQQGRLVGTGAFGSVYLGVNLDSGSLMAVKEIRFSDVNSLSTLYKGVKDELSVMEMLSHPNIVEYYGIEVHRDKVYIFEEYCQGGSLASLLEHGRIEDERIIQVYTLQMLEGLSYLHSKGVVHRDIKPDNILLDHMGVIKYVDFGAAKILGKKQKTLASRAHQHPVGHHAHDRPHFPPAPPPPGFPSGFGANSLTGTPMYMSPEVIKNDRRGRQGAMDIWSLGCVVLEMSTGRKPWSNLDNEWAIMFHIGVAAKPPPLPDPSQLSEFGIDFIHRCLTIDPIHRPTAAELMEHPWIADFRDEMLEYEEDEVVSIATPSMTTSHTNVSEHFEMATVARQAQKIEEEETAVMKSESPPDITPNENGEGIFLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXA6</accession>
    <name>M5FXA6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_88412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629510.1">
        <property type="nucleotide sequence ID" value="XM_040776851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXA6"/>
    <dbReference type="STRING" id="1858805.M5FXA6"/>
    <dbReference type="GeneID" id="63691913"/>
    <dbReference type="HOGENOM" id="CLU_004955_0_0_1"/>
    <dbReference type="OMA" id="PHPKKPW"/>
    <dbReference type="OrthoDB" id="49511at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052587">
        <property type="entry name" value="TELO2-interacting_protein_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057566">
        <property type="entry name" value="TPR_TTI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049362">
        <property type="entry name" value="TTI1_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460">
        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460:SF3">
        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24173">
        <property type="entry name" value="TPR_TTI1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21547">
        <property type="entry name" value="TTI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTI1 N-terminal TPR" evidence="2">
        <location>
            <begin position="15"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="3">
        <location>
            <begin position="808"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1121" mass="122667" checksum="457E85CB7213B124" modified="2013-05-29" version="1">MNEYDEDKARVQEAFQKLKPTCVALLGKSLLSPTSTSIVLSLLSTLNQTLLSLLSTPQVLTPSLISYAFFPLSSILRRNTSAAIPDQVLEQVLRCMALLWEEWWWVCDPEEGEWSQCWILGGSVLLDLGDGKEGKGKGRARDDETKDAAVTLLLALLRPWADEEARSGTTASDRLSKFRTLAQGKHLSLLGQTLSSLLETDLSPHAPLQIHSLELLNILITSYFDTSHVPSFLPGVVSSCSKVALGRERAAHQRGEVVNLALELLAQTMVKGIGDEVCRSAGLIRSVSSLDDLLDLATPASANATSTPKPEEKAQPHKHFTVPRSQAWYRATSSQLLMALNSLNPLLKHPSPQAQEGLATLHALLLRACSESLPDIVPLMIAILLSLSLSPYPDISDRAKHALIESLSTSNPAVSHLLRITTTSLSSLPRYLPSGLDSQIQTAAQQITAAAQLALEPDLSHLADGVAQLLGPNGGIEKWGLSLLHSLHFVLPPVALYTNASKLLESSPTELPQFPAFELKNVTSHQTLRALEDLFRSFGRAGGQEGLYAAEWFVTVGKRRTAVGVAALWVAGRLLEGIANVKLGVEGGRETPGKTLSKFCRWLARNVAELWDNDDDGDEEDVPPATTDEDSLLPIERVSGINQIQTLLDLRNDTRGSGAQSSRSSRQSLIPIHASFSLHMLALSSQVLTSNYRSLFLQVLYPVLHSLVSPIPAVSATAMCTLQVISHSTSYASPANLLLSNFDYALDAVSHRLTRTRLDLQATSVLVVLVRVVGKDVVDKAGDVIEQCFDRLDEFHGYSVLVEGLMSVLGEVISVLEPDEPPPTKKGASRPEEEEVSDFASFVHWYGHRDDPPAPEEPEDFGPTPQEPWTSPDKEDEKPPEDEEIPPTPSQALGKQIVAKSLYFLTHGSPLIRARVLHVLTSATPLLRESDLLPSVHSAWPFILNRLEDPEPFVLLEAATLVCALVARAGEFMSTRVSDDVWPRFRKLLLRLAAADGQTAMARRRQGALVADPYSTAYKLYCAVLATLTQAVRSARLKEQDTWEMAMLCRRLLTRETQGELQAAGRELFGALRERNADAVWLLLVGTVGEDLLPDEQVHLPGFLREPSWEIEDNARLVLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXR3</accession>
    <name>M5FXR3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_29709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628186.1">
        <property type="nucleotide sequence ID" value="XM_040774321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXR3"/>
    <dbReference type="GeneID" id="63689383"/>
    <dbReference type="HOGENOM" id="CLU_013985_19_8_1"/>
    <dbReference type="OMA" id="YEYNERS"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:protein-N-terminal-alanine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF11">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="12100" checksum="4AEF15068B824D90" modified="2013-05-29" version="1" fragment="single">VGVVSLRLENPKNRDAQLGMMFSPEWQGLGLGTELLRWLIPHAFDQLGLHRLSLNVKASNEGGKRLYEKVGFVLEGRRRAALWEDGGWVDILEMAIIADEFGKRKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXU6</accession>
    <name>M5FXU6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627502.1">
        <property type="nucleotide sequence ID" value="XM_040768702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXU6"/>
    <dbReference type="STRING" id="1858805.M5FXU6"/>
    <dbReference type="GeneID" id="63683764"/>
    <dbReference type="HOGENOM" id="CLU_1704183_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16808" checksum="A5DB21970494EFA8" modified="2013-05-29" version="1">MAVLGPALYRTIFYLLALLASIAELGVSAALLSLENEDLGAGEAFAQFVVSLVCLFLVLLGEVFVRLRFLASTSFELGVVGLLWVMWLASAAWTTSEVSSTFGVGNCDESSSQIVNWTIEMTLSDAEAMCREWKAVEALAWINWVFGSLNRPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY06</accession>
    <name>M5FY06_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="9">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="9">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="9">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA1</name>
        <name evidence="10" type="ORF">DACRYDRAFT_22557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="9"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY06"/>
    <dbReference type="STRING" id="1858805.M5FY06"/>
    <dbReference type="HOGENOM" id="CLU_095765_0_0_1"/>
    <dbReference type="OMA" id="FYQHKGG"/>
    <dbReference type="OrthoDB" id="204928at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000131">
        <property type="entry name" value="3-hydroxyanthranilate 3,4-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF3">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="20076" checksum="B503F78CED3EE0FD" modified="2013-05-29" version="1">MIPPPLNLPKWLAENSDKLAPPVNNFCLYDGGDFIVMAVGGPNERNDYHVNETEEWFYQHRGDMLLRILDGDEFRDVNIREGEMFLLPGNTPHNPVRFENTVGIVIERKRPEGSTDRLRWYCRSQTHSTPHIIREERFHCTDLGTQLKPLIRNWMEDESLRKCECGWVAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY97</accession>
    <name>M5FY97_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_106209</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629925.1">
        <property type="nucleotide sequence ID" value="XM_040768222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY97"/>
    <dbReference type="STRING" id="1858805.M5FY97"/>
    <dbReference type="GeneID" id="63683284"/>
    <dbReference type="HOGENOM" id="CLU_396989_0_0_1"/>
    <dbReference type="OMA" id="VIARTWE"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047274">
        <property type="term" value="F:galactinol-sucrose galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="779" mass="85175" checksum="285D7E80159EFF4E" modified="2013-05-29" version="1">MADSLVHEIFTDFDQSKVKIEGISLEGDGTTCYALLFDLKSSKSGEIDEFLLGNVGDKAEHSIRLTRDKAWWLFPTPNLDLPANTDTQFILLKLASSKYKYAALLTITVPAYMGTLRGKDGRIVARFERDSGTGGQGKIVVCMGNDLMGVVRGAADGMREVRGWGNSLLDAVVEGVERMMGNGGQGTIFSDTLTYCTWNSLFPVPRTAASVLKTLTSLKSFRIHPATLLIDDAWQSINDESGGPYTRLRSLTSFEAWDKFMDGIKGGLKEFVTRVKEDYGVERVGVWHTISGYWQGVEPVAFREKYKLVKVTLGDYPGPWEGAGFQYYIPHPDSVHQFFADYYRFLSACGVSFTKCDNVASLDALVSAREVRWEKGEGVLGAAVDMPTLRRNARQAVKDAAEKYFGGSEEGRVIWCMEMSPRIYLGKEVGGSTGARMVCRNSDDYFPDIMDSHRYHIYANVLNGIFTSQMNVVPDLDMFQSHAYIPEGEDVQKFSTEGTSAQAEYHAALRALANGPVTLTDVAGHTDPTVLDKLLGKSSKSGRSVALQAKKAFFVGPSVFEDLLSEKTGMGLKVYSEGEYGGGVLGVWNVRSKEGTAEDKLTFADILLLTSPSPERTTYAVHSFKTSKVYLADKAVSSIIPCEAPIQLEPFGFDIFTIASFVTSERCTIACLGLTDKYNPLSALTGPAVFLDNSPVLFGATFKCVGCASFVVKRLAGAGAGEEGAGKIKVVVGQTPVEETLIQRRVDERIGEIVTVDFRGLLRADPGEGDVYEMVLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYC1</accession>
    <name>M5FYC1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_83741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625449.1">
        <property type="nucleotide sequence ID" value="XM_040776637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYC1"/>
    <dbReference type="STRING" id="1858805.M5FYC1"/>
    <dbReference type="GeneID" id="63691699"/>
    <dbReference type="HOGENOM" id="CLU_019845_2_0_1"/>
    <dbReference type="OMA" id="WRSKYEK"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="40142" checksum="A2518E572529AEA4" modified="2013-05-29" version="1">MSNDSSNPNIVILGAGGSGSRVAHHLSQSSPKKYNIILVDQRGYYIHWPAMIRMVVAADHHIAENALIPLDKNWVDGNGKLVVGKVESILPAKGSTGGEVVLQSGERIPYAILVLATGSTFEGPLALPDTKPETVQWAQDWHKRIDAARSIVLVGGGAVGAEMAGEIKDIWPEKKVTLVHGDRALLNDTYPEKFRQCVAQGLSSRGVEFLFSDYVDTLPAPGESVTTRNGKILQADLVIPTRGGKPNTDLIRAAFPNTVDAQGRVTVLPTLQIPGHPTVFAAGDITSLPEQKQVAKYPSHASLISSNILALTAGQAPEKKYKPQIEMILITNGKTGGSAYVGLLWGLMLGDWFARTMKSKELLVGMARKALGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZG6</accession>
    <name>M5FZG6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_101572</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625859.1">
        <property type="nucleotide sequence ID" value="XM_040767566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZG6"/>
    <dbReference type="STRING" id="1858805.M5FZG6"/>
    <dbReference type="GeneID" id="63682628"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="TIMANVW"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="49870" checksum="BE7956478866E74B" modified="2013-05-29" version="1">MPFTLSFYHFLELGAVGAVLALYFLYRSQRLLPPGPNPIPLIGRTRFPIEHLEAFKSWAEKYPDIMTLRIRGQNVIIVNSLCAANDILEKRATSTSIRPQRPMCHDLVGYKNSTSQTNDMVQHKIYHFWAVEERELRKATLYMLNVPGDSTKALRRAMSAIVFYVAYGYNIETDGDAFVNRITDYMKVYQRLLRPADFLVDILPPLKHLPEGFPGAGFKRTASKWRKSKEDIHNVPFEQVKCDMASGNAMPSFTQHLLEEMPEQKGTNKYTEECIKLAASSIYTGGNDNNTSSVQSMMAAILLFPQVQDKAQAELDRVIGRDRLPSVKDLDDLPYCGAIVQEILRWQPPTPFALPHALDRDEEFQGYILPKGATIMANVWAMTRNPTSYPSPEEFIPERHLSTDENGNFKLEPTRNASPSGLAVVRVLALTWLKPLFSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G023</accession>
    <name>M5G023_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase M17 leucyl aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629001.1">
        <property type="nucleotide sequence ID" value="XM_040772584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G023"/>
    <dbReference type="STRING" id="1858805.M5G023"/>
    <dbReference type="GeneID" id="63687646"/>
    <dbReference type="HOGENOM" id="CLU_013734_7_0_1"/>
    <dbReference type="OMA" id="MFAQATV"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="5">
        <location>
            <begin position="158"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="34844" checksum="8772DB766A140E80" modified="2013-05-29" version="1">MELPANLMTPTAFCARMVKEFQGLGNVRVNVRDEAWAEEKGMRTFLSVTKGTDEPAKFFELHYSGAPAGEKPLAFVGKGITFDSGGISLKPAEGMKLMRGDMGGAATLLSAALAIVKLKLPINLVAVAPLTENLPGPKANKPGDIVYAMNGKTVEIDNTDAEGRLVLADALYYVTSEFKPHTVIDAATLTGAMMIALGEPYAGVFTNSDSLWNELQLSGKEEHDRFWRMPLDDDYVPQISQSNADLQNTGGRPAGACTAAIFLKAFVDGVEGEGSAQPRTRWAHVDIAGVMECTRPGPYQNKGMTGRPTRAFIDFARRLAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G066</accession>
    <name>M5G066_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626089.1">
        <property type="nucleotide sequence ID" value="XM_040770500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G066"/>
    <dbReference type="GeneID" id="63685562"/>
    <dbReference type="HOGENOM" id="CLU_106356_0_0_1"/>
    <dbReference type="OMA" id="FTIEPHI"/>
    <dbReference type="OrthoDB" id="2506317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="16640" checksum="7D0A9DFE8ACF2898" modified="2013-05-29" version="1">MPDAQSQQQYRAATHVPLIQSPSLRIPQPVLMPQDIHPLPDSLEPYMVYPFTLESRTLTSHAHLLNSLTALQSTHDQKLAAWEQEKQRRKREALRRVAPGFEPGVGVLVPDRAEVKPHASEVQAAEGAVQAGVMDDFVAGLEKMGYGALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G089</accession>
    <name>M5G089_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_102570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624085.1">
        <property type="nucleotide sequence ID" value="XM_040767641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G089"/>
    <dbReference type="STRING" id="1858805.M5G089"/>
    <dbReference type="GeneID" id="63682703"/>
    <dbReference type="HOGENOM" id="CLU_014832_3_3_1"/>
    <dbReference type="OMA" id="ADHVQIT"/>
    <dbReference type="OrthoDB" id="18915at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="8">
        <location>
            <begin position="151"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="371" mass="41254" checksum="5FB0D40C6C0FD15C" modified="2013-05-29" version="1">MHYFAPQQSVATGDETHRSSSGEGMSRTLQLALQESREITPMGIAGEEGGTDRVPQSALFPDGTKNFDEDEEEIQVEGELTDVDGINPEMKLSDLTDAQIIRLTQDLQEEESARRPLISPIEPLSELAEEYATGSRTVVDKLSYLERIGWRGVRRTRGDGDCFYRSLAFSYVERLLLAPDPALAVAMSLSTLQETRHLLDEAGFQQLVYEDFYDVLVRLISSIISPPGPYEPLLSSPGLLAAFQDAETSNSIVVYLRLLTSGYIRAHEEEFLPYLFSPDTGDLLDTRDFCEREVEASGKEADHVQEMALARALNLCVRIAYLDNSLGGQGAEGKVDFVTFESEQEGGNGMHEIALLYRPGHFDILETRDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0P2</accession>
    <name>M5G0P2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628577.1">
        <property type="nucleotide sequence ID" value="XM_040768464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0P2"/>
    <dbReference type="GeneID" id="63683526"/>
    <dbReference type="HOGENOM" id="CLU_416786_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="658" mass="72650" checksum="ADFBEADE78D98945" modified="2013-05-29" version="1">MTAGFAGGTRLGGKTWQGGEVALVVVRPQLAVIVQWVGFGGGERVWGEDLARGEIVPVVARPRTIAANTLPGNKDMLDKWGDALGVVFDFTEEDLSYRPDPSMLVMASQTATTVTGPAPPLQTAITLTQPVPPQPEQLTSHVAPQPEESTTLVDSGVAVLIDTREQIRKEYAERCAVKLPAKLRECPLKNPPAVSTDDGYLGPHIDALCTRTACLPAYRFDEKDEDPCHVLERLESLGRIYGQFIRMREEGVELLNEPRLRIPWDWLLSIIPFYPGPRWYPQIQYTCEITMAGPINPNTKRIIELEQKGTTYSLRSARNDGTLLLQVSKTTQDAITVIKRFNHVGVRQFHWEVTSQPNRTTLIVLPVEFKTRNLHLNAIQTCYGLVVGQSVLAAFDIRNQVLFGIAACGPAHAHILGAKWGGESLYITLCATLSLHMAEDFWTLYCFLFRTEQSARTTLNTAVENKVRSYSQGQSFRIWKDPGEGQTQPDISRKRKANDSVSSSASRPTKRLNTANAVLSAPATSVAISAAATLPSQSSASNQYSPMISSPSSGSLYLNQLQLFNIDELKLFHSPVNAHNLGTYDPNPCLFGMALEPVHDTAIECNSTNSDDSLEDSRSKIESWLHVHQDTAPPPLEEYARSPYECAKSPHNGNHFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0P4</accession>
    <name>M5G0P4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_59261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624270.1">
        <property type="nucleotide sequence ID" value="XM_040775548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0P4"/>
    <dbReference type="STRING" id="1858805.M5G0P4"/>
    <dbReference type="GeneID" id="63690610"/>
    <dbReference type="HOGENOM" id="CLU_012062_28_1_1"/>
    <dbReference type="OMA" id="FIEMADD"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="167" mass="16618" checksum="8AD4F0145E36C55D" modified="2013-05-29" version="1">MLPDARSSRSALEYAHIGNLSWNTNDDTLRSAFSQFGQVLDCIVMKDRESGRSRGFGFVTFGTSQEAQAAIDGLNEQDLDGRRIRVNLANARPPQGGSGGFGGGGGYNGGSGGGYQGGGGYGGGGYGGGRGSGYNSGGYGGGGYGGNSGGYGGGGYQGGSYGGYQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1V6</accession>
    <name>M5G1V6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624625.1">
        <property type="nucleotide sequence ID" value="XM_040770777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1V6"/>
    <dbReference type="GeneID" id="63685839"/>
    <dbReference type="HOGENOM" id="CLU_1390186_0_0_1"/>
    <dbReference type="OrthoDB" id="3365607at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="196" mass="21610" checksum="A0AED1FD8F948FF8" modified="2013-05-29" version="1">MSPFTFSAGTITPHRLRKRSTSPKEPRQRVRQSETPSGIPRLRRQESTPSIERVDTSSPTKTTRAQTPVSTRVKRPSTAPCQPPSSQQPEAADSLLSPSTSLPTFDTLDSATLSQLEQLSLELLALTASTASTPPRRKNILTRSPRLDNIVEVDTPQSDRGGVVMHGTPCAMETRTAEDVWREVGRLGRELKELAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1W9</accession>
    <name>M5G1W9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.186</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_23445</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23360"/>
            <dbReference type="Rhea" id="RHEA-COMP:14604"/>
            <dbReference type="Rhea" id="RHEA-COMP:14605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140573"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56560"/>
            <dbReference type="Rhea" id="RHEA-COMP:14606"/>
            <dbReference type="Rhea" id="RHEA-COMP:14607"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140574"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="10"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626794.1">
        <property type="nucleotide sequence ID" value="XM_040773243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1W9"/>
    <dbReference type="STRING" id="1858805.M5G1W9"/>
    <dbReference type="GeneID" id="63688305"/>
    <dbReference type="HOGENOM" id="CLU_003372_0_0_1"/>
    <dbReference type="OMA" id="HAVFPWE"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000092">
        <property type="entry name" value="Glycogenin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="379"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="614"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="714"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="989"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="468"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="717"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="751"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="801"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT99896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1060" mass="118140" checksum="E68AFAED706C781D" modified="2013-05-29" version="1">MTTPLAAPAADPPYAFVTLVSSDSYLPGALVVAHALRDVHPKPANAPEVDFQTVCLVTPEVVDVATIRALRQAFDLVVGVEVIDDQSQLGVENLGLLGRRDLTTVLTKLHVFRLTHFRKIIFLDADVLPLQPISHLFKLDFSQKLAAAPDAGWPDCFNSGVMVLQPSEASFGELRDLARTRGSWDGGDQGLLNEWVGNDWHRISFRYNTTPTAAYTYKPAYARFHEEIKLLHFIGSHKPWASLPIRPSRPPPRPLHESHDTAYGALVDQWYAVYDRHYRPLSNVDDFLPEDYQPGPGPEATTTTTTAPSFQPPHYAAAWDEPKPFEAQPEAGPVYGLEELRELAVKGVGSAYTVTDGEGRYESLPLEGRVDLLCPKFEEEEEKEDEDVTPKASDYQLPPPPVQMGEYPPHLQRPPAPPPPPLPPVHAPQPVQEYFPPQPAYQEHQQPGPSVHHEQAWHPEPTYHEPQWQPPPPPPPQQQEQGQPPPPPPQQQEQWQPPPPPHQDWQPPHEEHQPYVPPPQEREEYHPPQPEPAAPAPPPPPPEPFSAPIMTWNPAHEPPPNKRPSHAPVFPEWTGNVWEQPSYRDQREFFHAPPPTQIPQHLVDQGQYEKVMHHAPDPRKVNPIFPWEKEGRPRTQRVWPEGEYPLPEIKPLLPEVGGLEGPTLTVQSPSPTVPPGRTFQEHQPPPSPPTYGLPQDMTFRNAWDADPHIQRYVSKLSRPSTVGSRQPSFAVMRRSSPLSTPGIKGNFAFRRPAERGEGADASSRDGDDEEDEQESESENGAAGAAEEVAEEGKPGRKSPKSRSGSVSSRGGESFGPSKAYRSQAVQTEPPPKKKSRGIQVQIPRTDFFIQREPKKDEGVQTPEMVMLEPHPPLESTHMPVPDAQYLLPQHHMPATPSPYDEPMMPTHKDGARGRLADVETDETPVQVLMPPPLVTTDTASATESYFLSTVESPREVAANPPNLHPGLEPLSPPLRPGPTPIPAHMRISSNETQSSGIGGSPPSSILMSPRDGEEMTSPRTQAARLAIRRWDPARDVDLFKRDSQEVLARFLRMNDWEEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G224</accession>
    <name>M5G224_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629162.1">
        <property type="nucleotide sequence ID" value="XM_040770109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G224"/>
    <dbReference type="STRING" id="1858805.M5G224"/>
    <dbReference type="GeneID" id="63685171"/>
    <dbReference type="HOGENOM" id="CLU_009568_2_0_1"/>
    <dbReference type="OMA" id="CETAMIC"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="885" mass="99412" checksum="2DB4016563BC5D4C" modified="2013-05-29" version="1">MATRRNLKHPRDEDSEMDNSKRLRGDLDSVRETYVKRWMRSHSSWTRNLRHLDVVEEGDEKTELEQELVDELTLSMIEEGNEISAALRNLALEIVRAVERDLAVLPIELGKLYDAIHPPRVADTRKRSTMHLVSVRAQEKATVKSWASEYEGNGVDLFHKHIAHCCELSGAGSSLYGKSFVIVNSSGMGKSRMVDESSKTLFTVLFVLRDARGGFPPPDSNVLAYFQRTRTVNECETAMICFLKTLYDELITLLKDRQEEAGTQKHAELAYWFRGYLATWTHMYDPSPARVDFFTRVVKKAEEMQDIRATHASPPEKDGDRILSSEVSTKERSRKSEMIDSFSTLSALLEHDPKSPLPSLLLAFDEGHTLLQRVGRREDEASIYSVLRRVLLYLDEKPQMSCFISTSTSIVEQSAPPMRLNPSSRMQSGLYRSLPAFTSLPLNMTRIQPDEMDLTLVSRDDFMCKQSRILFRTRAEHGVDSDVGENLGSFAMEKLVGASYGLDFDDGQKLAILARRIPIHMQTDTSASLRTINEQIARHMRVLYRITDNNETLITGSPSEPIISEGAKAAMATFNAADALRRIFVSPGISVDDRGQMVAALLMILASDAATKYGKFSIPAFFKCLLTDVSWMTLKSSQASHGRIFHPERFEQTFENSFGNFNHVIKVYGNVPRSNSLYRYLTRRAAISTLFAQPGVDGAFPYTIDETKITPDNTSFAIIQTNAEAGMQIPPKSAFDNMNSIVRQMHDYHDAESTPAPKHKNKYKPVIRMIFSLQSKETDLVVMEYEDADDELVTWDIYVPFLALGAVQENAGMWQSVLETGLQSGSIYDGDVTLMGMDPGAKDGDEFWPNWAPTEEGSSGHTRDAKVKEEGKGSSNPKGKGKASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2B3</accession>
    <name>M5G2B3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_107281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629249.1">
        <property type="nucleotide sequence ID" value="XM_040768441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2B3"/>
    <dbReference type="STRING" id="1858805.M5G2B3"/>
    <dbReference type="GeneID" id="63683503"/>
    <dbReference type="HOGENOM" id="CLU_013985_41_3_1"/>
    <dbReference type="OMA" id="IAVKCRC"/>
    <dbReference type="OrthoDB" id="7305308at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000064">
        <property type="entry name" value="GNAT family acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051016">
        <property type="entry name" value="Diverse_Substrate_AcTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545">
        <property type="entry name" value="DIAMINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF29">
        <property type="entry name" value="GH14572P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="18007" checksum="EF9EC425B6AC31A8" modified="2013-05-29" version="1">MSALPEILRLILGLAIYEKAPESAQATPALLKQNLFGAHPYAHTLLAFVDGKAVAIAMYFFNFSTWKGKPGLYLEDLFVEPEYRKMGIGKALFGELGRVAEVHECGRMDWSVLKWNQPSIDFYEKALGAFGMKEWEGMRLEEEGIKGLRRLRVPEATAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2D5</accession>
    <name>M5G2D5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_88547</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629748.1">
        <property type="nucleotide sequence ID" value="XM_040776862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2D5"/>
    <dbReference type="STRING" id="1858805.M5G2D5"/>
    <dbReference type="GeneID" id="63691924"/>
    <dbReference type="HOGENOM" id="CLU_073125_0_1_1"/>
    <dbReference type="OMA" id="EMFENHT"/>
    <dbReference type="OrthoDB" id="2138173at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.109.10:FF:000001">
        <property type="entry name" value="Nitroreductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035:SF1">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="203" mass="23353" checksum="06041260D7F2F799" modified="2013-05-29" version="1">MSEAFFELVKARRSYYALSNKTPIPADRITKIVEEALLFVPSSFNSQSSRVVIVYGKEHEALWDLVLEVLKPVAPPEQYPRTIEKVNACFKSGFGTVLFFEDNASVIDMQEKFPLYQDRFPTWAQHTSGMLQYIVWLAFEKEGLGASLQHYNPLIDERVRDKFNLPVTWFLTAQMPFGNIAAPADPKEFMPMEERFKVFGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2W1</accession>
    <name>M5G2W1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629928.1">
        <property type="nucleotide sequence ID" value="XM_040768223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2W1"/>
    <dbReference type="STRING" id="1858805.M5G2W1"/>
    <dbReference type="GeneID" id="63683285"/>
    <dbReference type="HOGENOM" id="CLU_086503_7_0_1"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="17766" checksum="177509486EA15764" modified="2013-05-29" version="1">MVALITKYNVYTLSHSIPSTATYRHLCRSGGLSDKSPSACAIGLPRSVFCVQILAASCMPGTDVTSTEFPEPDSIEEQPDPRVVGMGRIIGDGTLFLQIVDIVLLPAHQHLGLGKFIMWELMLWIEAPCPRVAGRLYERFGFGFTEASGSRGMAYTVRGKGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D5</accession>
    <name>M5G3D5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 11">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_78585</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 11"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629624.1">
        <property type="nucleotide sequence ID" value="XM_040776351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D5"/>
    <dbReference type="STRING" id="1858805.M5G3D5"/>
    <dbReference type="GeneID" id="63691413"/>
    <dbReference type="HOGENOM" id="CLU_013325_13_1_1"/>
    <dbReference type="OMA" id="PYLENYM"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.20:FF:000003">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="12">
        <location>
            <begin position="348"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="432" mass="48161" checksum="596DCEB7F08DFBFA" modified="2013-05-29" version="1">MGDISLPAPLPPPTWPNRFQHVDTLLDHPGPSTDPDFVGGEAVKRFLREDSKVLVIGAGGLGCEILTNLALMGFADIHVIDMDTIDISNLNRQFLFRPKDVGKPKAIIAAEFVMSRVPGTKVTPYFGKIQDKPESYYMQFNLVICGLDSVEARRWMNATLVAMVDPDVPESLKPMIDGGTEGFKGQARVILPSITSCYECSLDMLNKQTVFPICTIANTPRLPEHCIEWASVLEWPKVFPDKKLDTDDPEHIQWLFTHASTRAREFKIEGVTWSLTQGVVKNIIPAIASTNAVIAASCCTEAFKLMTNCAPRLDNYFMLIGTEGVYSYTFQHERRPECPVCGGETIDMPVKKEWTLERLIEALEERQDIQAKKPSLSVNGRSLYLQAPPQLERATRPNLEKKLVDLVNDGDELTVTAGSLPFNLTLRVLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3E4</accession>
    <name>M5G3E4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631630.1">
        <property type="nucleotide sequence ID" value="XM_040769754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3E4"/>
    <dbReference type="STRING" id="1858805.M5G3E4"/>
    <dbReference type="GeneID" id="63684816"/>
    <dbReference type="HOGENOM" id="CLU_020130_0_0_1"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="399" mass="44295" checksum="FED07CBABD8499E6" modified="2013-05-29" version="1">MSCRGPVPGTPARGEAGRTLRQMANVLVDDIFPGVHVTTGSLQPFLKKGITNDDRLAVHSVKVALGEFVAAMVIDGHGGEECAAYAQHGIILRELDRCGSICSCTEISGALQRAIKAFDDDLARALKESVTKVPPGDSLSTTFLRDRPLRRLLRCFRGACVVVVLIRPSSRDLWVANLGDCLVVEGHENVEDPSGSWIVRRLTEEHNTSNKDEVKRIQDEHPGEECILDDLVIGRIRPTRTVGNWDQKWPADMVAPLYPFLPFVGDGKPRGRTRLLNISLTPPYQSSVADVRHEKLPSGRGVLIVASDGLPDNCARLTLDPHPDVERRNQEMIESWVRSANRKPLEGLEDVEVTAVERIMRDVLGGTEERKVMINLTDWFHVNIWDDMTVVAIELFLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3F1</accession>
    <name>M5G3F1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_75636</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631640.1">
        <property type="nucleotide sequence ID" value="XM_040776148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3F1"/>
    <dbReference type="STRING" id="1858805.M5G3F1"/>
    <dbReference type="GeneID" id="63691210"/>
    <dbReference type="HOGENOM" id="CLU_007339_0_0_1"/>
    <dbReference type="OMA" id="YKFAEAK"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="9">
        <location>
            <begin position="38"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="10">
        <location>
            <begin position="654"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="761"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="55"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU04746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="847" mass="94465" checksum="EBD2F3CEF3EDF01D" modified="2013-05-29" version="1">MPHATLPPELLDQVERVLNARTVHEGGGSSGQEEPLIDFSLLNSLNKLFPDEASLERIEQVQADLKAQHAALQQEIIELRAQLRQESDATRMQTIQALIAELLSQMTRIREKATESEAIVRELTKDMQALDLAKRNLSLSLTVLKRFQILVNDLGRLDGLVQERKYSEVAPTLGAVKQIATSFRPYASVDKIALGMKRMQELTGQLRTELDEDFEAFYNQDRQKPIKPSTIRSACEVVDVMGTDVRLSLIDRYCALQLKEYRRIFRSTDEAGQLDNISRRFAWFKRVLNAHDEERGDVFPKEWRVEQYLCAKFTDITRDDLAVALTRAGQKLTVALLLEALKETLEFEQTMSRKFDTPFLEVVGVAASIAKPPAMLSGVFDTHMGVFVDAQDKALSDMLAGYRGTKSRASLDEATSDGNNQTVLGSSTDLFYFYRQILEQCAKLSTKQALFDLCSLQKKWLRIYAEDVLTCSDKEGRSFDRKSADGRVNISELKNASLVLNTAEYCHATAAQLEERIKELIHPDYREKVTLQPEQDVFVGVIASAISVQLKELEAATDPSFAVLSRAGWGEVTSVSGPSNAVMDLVKTVETVGEGLKEQVQYKKWLRNFYDKAAHTLMTRFSHAVVKSRPIKDVSAEQASMICFSQPFILIHTQIMIDLQTLRSCILELPGTQPGETLSSYIKNITKTTTNLETVLKLVIAPVIPADAFVQNYTLLIQDSSFSNFQKILDLKGTPRAEQNTLLDTFLTVTSHMEHLESTSFLSSLDMDPDNKQTQPSTLGRTLTSPPMSGSRVTLPSILVGSGAIAEEPGSGALSGSSTSKGEQPRQVFSNLRSFMAFGSRRESVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3U4</accession>
    <name>M5G3U4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MDE1</name>
        <name evidence="10" type="ORF">DACRYDRAFT_50569</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3U4"/>
    <dbReference type="STRING" id="1858805.M5G3U4"/>
    <dbReference type="HOGENOM" id="CLU_006033_4_0_1"/>
    <dbReference type="OMA" id="WFPGTSG"/>
    <dbReference type="OrthoDB" id="191080at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000003">
        <property type="entry name" value="Methylthioribulose-1-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="9">
        <location>
            <begin position="49"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="30226" checksum="EE25CBE75D22113A" modified="2013-05-29" version="1">MSISRHSSTAKYTRLDEHQHHDDEDDESIHSDGTVDELIQSDDPEHPANLIPELCRGFYTLGWVTGTGGGISLKSGNLVYLAPSGVQKERILPEHIFVLPYPQPAVVKAHTERTFLRKPKQEGLKESACTPLFWNAYELRNAGACIHTHSQHAVMATLLWKGEVFEISHQEMIKGIRIGGTGKTLSYLDTLVVPIIENTPHEEDLTESMSEMMQKYPDAAGILVRRHGLYVWGPTWQSAKTQAECLDYLFEIGVKIKLMGLPVCPAKEGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4G7</accession>
    <name>M5G4G7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MCM7</name>
        <name evidence="15" type="ORF">DACRYDRAFT_61555</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4G7"/>
    <dbReference type="STRING" id="1858805.M5G4G7"/>
    <dbReference type="HOGENOM" id="CLU_000995_7_2_1"/>
    <dbReference type="OMA" id="AQHVTYV"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="370"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="717"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="791" mass="88847" checksum="FB21228F2024BF83" modified="2013-05-29" version="1">MTAVPVIALNINYAEEESKIKGFLENFKTSTNDVTDDFEHMGLDDDETPGEDMAAKLKGHKYMSQLQRIANREQQELCIELEDIADFQDGVHDLVSNIQHNARRYVDLFCKAVDDLIPAPTKDISHHDDVLDVIMHQRKEHNEMAQVDAQQDIEGAPAPLDRQFPPQLMRRYNLYFQPFASDETLAVREVRGEHLGKLITVRGIVTRISEVKPLLLVNAYSCESCGAEIFQEITHKQFSPLTDCTSERCRQDGVKGTLSMQTRACRFSPFQEAKIQEMADQVPVGHIPRSMTIHFYGGLTRQVNPGDVVHLGGIFLPTPYTGFRAIRAGLLTDTYLEVHHVDQVKKQYSALEMTPEIATQLEHLKSDPMLYEKLAQSIAPEIFGHEDVKKALLLLLVGGVTKQVGDGMRLRGDLNICLMGDPGVAKSQLLKYISKVAPRGVYTTGKGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNPRISPVENINLPAALLSRFDLIFLILDKADRDADEALAEHVTYVHMHNCHPDLSFEPISPLLMRHYIALARTKRPVVPRMVSEYIVGAYVTLRKRSRDEEQDEKMHSYVSARALLGVLRLSQALARLRCADTVELADVDEALRLMDVSKASLFDEERDDNDRGDQTDMSKIFRIIKEMDKRRRPRRRLGRGPNRERDYQEEEDGPLLMADVRARVIAGGFTEIALMDTILEYERMGVLSRIANGTKLQFAAQDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4T3</accession>
    <name>M5G4T3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_49118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630573.1">
        <property type="nucleotide sequence ID" value="XM_040774883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4T3"/>
    <dbReference type="STRING" id="1858805.M5G4T3"/>
    <dbReference type="GeneID" id="63689945"/>
    <dbReference type="HOGENOM" id="CLU_029724_1_1_1"/>
    <dbReference type="OMA" id="PAKYWDI"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="6">
        <location>
            <begin position="124"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="324" mass="36907" checksum="456EB9CD04413201" modified="2013-05-29" version="1">MDEATPGESKRTASTQTSGAPPPFGSRFLTPSRSVWEQNAWDHVPPPDDQGERIALSLERQRASRVSDADRNRYNARPEKYWDAFYRLNQGNFFKDRKWLHLEFPELFQATREDAGEVTVWEPGCGVGNALFPLVQENENDQLKLVGCDYSKKAIEVVHANPLYHPPKGSLHAQVWDLASPLGLPESIPPGSVDIVLLIFVLSALHPDEWTRALANIWTALKPSGLVLIRDYGRHDLTQLRFRTNRLMEENLYVRGDGTRVYFFELGELGGLAQTQSPLPPAYPLPPHPLFSAQQLGIDRRLLVNRKRQLKMYRVWVQAKFCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Y8</accession>
    <name>M5G4Y8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630184.1">
        <property type="nucleotide sequence ID" value="XM_040777604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Y8"/>
    <dbReference type="GeneID" id="63692666"/>
    <dbReference type="HOGENOM" id="CLU_927561_0_0_1"/>
    <dbReference type="OrthoDB" id="10630426at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="33097" checksum="8A0B9D654B3559AA" modified="2013-05-29" version="1">MKLDFVGRGRSMSAPPAFTLGQKQTMMGYIDPAPLISAETYNLPLITGRPSGASARYSRPASASSRRSRRASLASTVSASVYSQQSAPRSPLSSSFLDGPSTPGTPDTPMSMMCPASAYAGSRRSSLGAPWSSYSEGNALHTTTSRISEVSASTLPTVAECPTCRSLAQQTPHDGPEDEGPTGPGRLGLRKLASLIFPNKGEREPVYIDQAHWSFYFPGVPHEGGCGCRGCVKRDPSREEGEEKRRDRVREYEQLRPWRWGWRKVRWITWTRERRALVRARGEASILGRVKVSRVYEVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G533</accession>
    <name>M5G533_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_53646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627849.1">
        <property type="nucleotide sequence ID" value="XM_040775187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G533"/>
    <dbReference type="GeneID" id="63690249"/>
    <dbReference type="HOGENOM" id="CLU_2873783_0_0_1"/>
    <dbReference type="OrthoDB" id="3037028at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7233" checksum="BBAD7F592C63AC59" modified="2013-05-29" version="1" fragment="single">FIKDFAMKAHPLEHLKCKGAIFAWGPEHQAAFDQLKVDACQDGLLCPINHDSNRRIILMVDSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5L2</accession>
    <name>M5G5L2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630883.1">
        <property type="nucleotide sequence ID" value="XM_040772038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5L2"/>
    <dbReference type="STRING" id="1858805.M5G5L2"/>
    <dbReference type="GeneID" id="63687100"/>
    <dbReference type="HOGENOM" id="CLU_868843_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="320" mass="36729" checksum="EF33EEFAEB4CA331" modified="2013-05-29" version="1">MERFFLPQGMNEVLVGLGILPIVRPKGQLKTPAACTRRQADFDAASVDRLLSLLEKESLLANWTLFARETAFQTGLELVSSAHSPEEQEALEQILEGAWGDHVWLGPHLDVYEGAIHLLYAALRRRGRSYAREPRFLAIQCWENQLGRQNWRTHINLHDWDASRSLPLRLGPSVSPAVRLQPFCWPPWLSSEEVPLLGCPSFDREFKFLSDFLIKGFCDSPNDYTTWVRLAESYSNSKGRTLFTAFDSPGSQRSDDPTPLMATSRTNFRLAEDRRDRTERNNRITWEIHCSRSPERRTDSNWRHPSREREAPAIHQTSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5N1</accession>
    <name>M5G5N1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_114908</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630419.1">
        <property type="nucleotide sequence ID" value="XM_040769906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5N1"/>
    <dbReference type="STRING" id="1858805.M5G5N1"/>
    <dbReference type="GeneID" id="63684968"/>
    <dbReference type="HOGENOM" id="CLU_030231_0_1_1"/>
    <dbReference type="OMA" id="KTQRYGT"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="13"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="467" mass="49995" checksum="DE33EFE55F38BDD3" modified="2013-05-29" version="1">MTTTSGTSNGILKSAEEIAKAAKAAYEESQLVTTEQRNDVLESIRRALQASRDKVFEANRLDLEAAEKEVQAGRLSQQLVKRLDLTKGSKFDDMLQGISDVAALPDPTGHVTYATNLDEEMELYRVTCPIGVLLVIFESRPEVVVNITALAIKSGNAAILKGGKESAHTAALLTSIVQSALSTSPLSPSFIQSVQTRQEISALLSQDRYIDLVIPRGSNALVRSIQKASRIAVMGHPDGLCAVYLDASADGTKAVRIAVDAKCDYPSACNSAETLLVHESLITTVWPKVALALLDKGVQLRCDAASLAGLRSSSEVSNNKSFASLVREVTTEDYDTEFLDLILAVKVVSSLSQAVQHINAHSSHHTDAIVTENAENGTLFCRAVDSAGTFVNASTRFADGFRYGLGTEVGISTGRTHARGPVGLEGLVIYKYMIRSADGKGSIAGEFGTGKKPFLHQKIQGVTRLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5W3</accession>
    <name>M5G5W3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_114520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631008.1">
        <property type="nucleotide sequence ID" value="XM_040769836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5W3"/>
    <dbReference type="GeneID" id="63684898"/>
    <dbReference type="HOGENOM" id="CLU_039658_0_0_1"/>
    <dbReference type="OMA" id="TYYEGAR"/>
    <dbReference type="OrthoDB" id="73788at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="354"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="522" mass="55972" checksum="0379A48444359F1A" modified="2013-05-29" version="1">MNTDLFFNPAASTPPPEAEGAGQPQQSLEEEVQQVVGQLGKFWGGFRKQSASAFDLAKKDFTSVVGQARTELSKLGQEASQRISQELSRPPTVTTPESALEEKSDTNAISEGAESAAEDIVPAVSASASVESTAAPAEGEASTSTTTPRSRAATATLFDRLQASLPSNIARAIPPTTSASLSALSRDITTQYHHFQTTFSADLNSIEAVAQEYAHKGEQILKDAGVRGEALYKETKDFLKEAVRNVPNDPAYAEGMVWDGTDLWQLPGLSASMNNGERREEIFSASSQAGPSAARSSGDMKVPTTRAEVLLAQLRRTPGVLRVDPTAEPRSAAEWESWGTEHWNEDWKEKVEGQETGELKETKDSLVPGELDEETFWKRYFFRVYQIERDEERRKALLNDAATTQKEEEIGWDDDEEPSTNALTTVAAAAASTATLTLPESTVTPRPSSSFEAAPAPPSGTSTPAGAGVIALSSGAPSPRQSSDDSFDVVGTDSATGTDAGVGKAKESKKEEKEDSEDSDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G626</accession>
    <name>M5G626_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626095.1">
        <property type="nucleotide sequence ID" value="XM_040773403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G626"/>
    <dbReference type="GeneID" id="63688465"/>
    <dbReference type="HOGENOM" id="CLU_3068629_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="53" mass="5818" checksum="FAAD54A1ACC3B418" modified="2013-05-29" version="1">MTHICHNTNRNGFRSCIRSWLDVGSTVQDPISHAPQVPNADDHGAVIQSFSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6E9</accession>
    <name>M5G6E9_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU01402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628299.1">
        <property type="nucleotide sequence ID" value="XM_040768564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6E9"/>
    <dbReference type="GeneID" id="63683626"/>
    <dbReference type="HOGENOM" id="CLU_1713184_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="16911" checksum="B37AF5531DC4024F" modified="2013-05-29" version="1">MNNVTRVAGGDAEVWEEVGDEEDEEEEQEEEGDEADGQSAECLLIYHKIDNLPHYLTPAASMSTGIMPASPSSSPHPSPPPTPCKKSNLPVITTFYIPTSAEVHVAWEDCNKLQDFQPPISAPRKHTTGFLACMFKHSKHRQHSNFTIPPLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6J3</accession>
    <name>M5G6J3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA glycosylase</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_42265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6J3"/>
    <dbReference type="STRING" id="1858805.M5G6J3"/>
    <dbReference type="GeneID" id="63689577"/>
    <dbReference type="HOGENOM" id="CLU_1829927_0_0_1"/>
    <dbReference type="OrthoDB" id="565731at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008263">
        <property type="term" value="F:pyrimidine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10028">
        <property type="entry name" value="UDG-F2_TDG_MUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015637">
        <property type="entry name" value="MUG/TDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159">
        <property type="entry name" value="G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159:SF9">
        <property type="entry name" value="G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE"/>
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    </dbReference>
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        <property type="entry name" value="UDG"/>
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    </dbReference>
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        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="4">
        <location>
            <begin position="41"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="141" mass="15535" checksum="9D2C94769E7466E5" modified="2013-05-29" version="1" fragment="single">EETSSPKRRKRSLNKRGYASPDTYAHLGLVHDYLGFGLDGSPGVMSAATGHHFANPTNHFWRALHQGGLVSRFVPASEDHTLPEKYNLGITNLVERPSIEAAKLSAKEMTAGVPAFLAKVKKWRPRIVCFVGKGIWLAVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G719</accession>
    <name>M5G719_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626455.1">
        <property type="nucleotide sequence ID" value="XM_040771269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G719"/>
    <dbReference type="GeneID" id="63686331"/>
    <dbReference type="HOGENOM" id="CLU_549834_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="55400" checksum="B07B402DBD4CF5B1" modified="2013-05-29" version="1">MEQEEAKGAVAVEAAVVVDVMEKKEDKPKHPKPHQIFQKTATMSPPNNSDEVEFMDNVPPGRATEQLATFMPRVHPPQGRGNTMESDMVEVVVPQRVMVKPICPINTKASKSMKNKGKARLSTWNAPELTNRLAKGFTLKAKPTTVAKGFQLLWTLYSLWWEVALLKCKECAKEDKRKGHVVRKTNSLAKVPNEGREWPKVVKPAKWEQVCVLLRQASSWLLMASTAMNEWVMEICLNQASLMFVLNTSHDEILYVHLPCKDTFAPMGMQYEMNLGTVKLINKGMKKCKAKDDDASTLQDIKKAKLMEHSGWSTSVPAELIYLSSDEEEPPYEEESLGAGTDEDEGPNSGLVGDRCGQGHPISHSIGICVIERSSDLSFYFSNMYGSEGLTPSAGNFRIVVPSGDDIRESKKSRVLARWDILGYCGVGRVILNAKTVMVCYIEEGLESWVKEIEDQLAEVVRQQAKRCNGIPSDATIKFRYHVRFAFIMADDNIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G730</accession>
    <name>M5G730_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_22681</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="3"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628514.1">
        <property type="nucleotide sequence ID" value="XM_040772923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G730"/>
    <dbReference type="STRING" id="1858805.M5G730"/>
    <dbReference type="GeneID" id="63687985"/>
    <dbReference type="HOGENOM" id="CLU_015846_7_2_1"/>
    <dbReference type="OMA" id="QPRANGC"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="253"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="558"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU01617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="695" mass="75928" checksum="C4E232A9ADEB08BD" modified="2013-05-29" version="1">MAFPTSSGSSLFKLSKKSSQRFTPSAQEYLASLKAADDDALAREQARSHSPTPARESYAHTTGTNYAPSIASTPALSFASTAASTISTPTTHAAQLEEDDDPLLVPDTPPTSNDPPPTALHSEFGYCNNEQYRYTSSYRPGTSLLPQHQDPPMTILLATYISYLFLIAIGHMRDFFGKRFWPAYYKHLQPADGYAALNGDFDSFYTRRLKLRIVDCFSRPVTGVPGRTILMYNRVSPDFNVTFKLTGQLTRALNVSSYNYLGFAQATGGVADAADESIRRYGLSALGPRLEAGTQDLHQAAEALVARFLGMEDAMVVSMGFATNSTTLPAMVSRGSLVISDEYNHASIRTGVRLSGASVRLFKHNDMSSLEQILRESISQGQPRTHRPWKKILVVVEGLYSMEGTFIDLPGLMELKKRYHFYLYIDEAHSIGAIGPHGRGVCDYFGVDPREVNILMGTFTKSFGAAGGYIAGNKVLIDRLRTINHSFAYAESVSPPVLTQLTAAMASIMGVAPPLPPAAVGAPGTLIPASAPYVHPGPAPASILPQWMHLPPLLLSGQEGATRLRRLAFNSRYLSQGLRKLGFIIYGHRDSPIVPLLIFNPGKMPVFSRLMLAANTHPNAVPFVVVIVAYPATPLITSRVRFCMSASHTKADVDRLLRACDKVGDLLDLKHGIPKGERWTVEEVVDRAVELVKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G736</accession>
    <name>M5G736_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_48672</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630914.1">
        <property type="nucleotide sequence ID" value="XM_040774860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G736"/>
    <dbReference type="STRING" id="1858805.M5G736"/>
    <dbReference type="GeneID" id="63689922"/>
    <dbReference type="HOGENOM" id="CLU_001570_20_2_1"/>
    <dbReference type="OMA" id="NEDSTHK"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16530" checksum="22C27BCFB44FBA1A" modified="2013-05-29" version="1" fragment="single">YQEVLYKDWVIPKGTILVSNIWQAAISRDPLTYPNGDEFHPERFLTSEGGIRQPPPDTHDDFLAFGYGRRVCPGRDMAIRNLRICAAFLLRAFGFQKARGEDGKEITPDSMAMLDTGSTVYPAPFRTRIISRQPDLEEQLPSCVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G763</accession>
    <name>M5G763_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Urease</fullName>
            <ecNumber evidence="3 11">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Urea amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_20266</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a nutritional role via nitrogen acquisition in the environment. Contributes to the central nervous system invasion by enhancing yeast sequestration within microcapillary beds (such as within the brain) during hematogenous spread, thereby facilitating blood-to-brain invasion by C.neoformans. Affects fitness within the mammalian phagosome, promoting non-lytic exocytosis while delaying intracellular replication and thus reducing phagolysosomal membrane damage, events that could facilitate cryptococcal dissemination when transported inside macrophages. Urease activity is also associated with the regulation of key intracellular metabolic pathways, including melanin biosynthesis, polyamine biosynthesis, as well as intracellular levels of proline and reactive oxygen species.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>urea + 2 H2O + H(+) = hydrogencarbonate + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="13">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="3 11"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631458.1">
        <property type="nucleotide sequence ID" value="XM_040771867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G763"/>
    <dbReference type="STRING" id="1858805.M5G763"/>
    <dbReference type="GeneID" id="63686929"/>
    <dbReference type="HOGENOM" id="CLU_000980_0_1_1"/>
    <dbReference type="OMA" id="DTMDGVH"/>
    <dbReference type="OrthoDB" id="1708534at2759"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035550">
        <property type="term" value="C:urease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00375">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00407">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00390">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.280.10:FF:000001">
        <property type="entry name" value="Urease subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.150.10">
        <property type="entry name" value="Urease, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.280.10">
        <property type="entry name" value="Urease, gamma-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01954">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008221">
        <property type="entry name" value="Urease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017950">
        <property type="entry name" value="Urease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002019">
        <property type="entry name" value="Urease_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036461">
        <property type="entry name" value="Urease_betasu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002026">
        <property type="entry name" value="Urease_gamma/gamma-beta_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036463">
        <property type="entry name" value="Urease_gamma_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050069">
        <property type="entry name" value="Urease_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009671">
        <property type="entry name" value="PRK13192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009682">
        <property type="entry name" value="PRK13203.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009686">
        <property type="entry name" value="PRK13207.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00192">
        <property type="entry name" value="urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00193">
        <property type="entry name" value="urease_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33569">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33569:SF1">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00699">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00547">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001222">
        <property type="entry name" value="Urease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51278">
        <property type="entry name" value="Urease, beta-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54111">
        <property type="entry name" value="Urease, gamma-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0533">Nickel</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Urease" evidence="16">
        <location>
            <begin position="398"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14 15">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="13">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="13">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="12">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001222-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001222-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU04564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="838" mass="90434" checksum="CD9D96FB459834B8" modified="2013-05-29" version="1">MRISPREEAKLTLHLLGSLAQKRLARGLKLNQSEATALIAAQLQELIRDGNHSVAQLMQKGKEMLGRRHVLPAVPSLLHEIQVEGTFPDGVFLVTVHDPICTDNGDLNAALYGSFLPVPSNQQFPLDAHELYERRAGPGAVIVRREPIHLNKGRERTKLRVTNNGDRPIQVGSHYHFIETNPQLSFDRAKAYGKRLDIPAGTAVRFEPGDVKTVTLVPIAGNQVITGGNRLASGTVDLDRTDEIVRNLIQKGFAHVPEPTAWIGAEVKEVSREVYAGMFGPTIGDRVRLGDTSLWIEVEEDYTVYGDECKFGGGKVIREGMGQATGRHSALALDLLITNALIIDWSGIYKADIGVKDGKITGIGKAGNPDVMEGVEASLIVGASTEVIAGEKLIVTAGAVDAHVHYICPQQWTEAIASGVTTHIGGGTGPSAGTNATTCTPSPFYIRTMLAATDTIPMNFAFTGKGNDSGPEALEDVVRAGAAGLKLHEDWGSTPSAIMNCLDVGDKYDVQVNIHTDTLNESGFVESTIAAFGNRTIHTYHTEGAGGGHAPDIIVVCEQENVLPSSTNPTRPYATNTLDEHLDMLMVCHHLDKSIPEDLAFAESRIRAETVAAEDVMHDIGAISMISSDSQAMGRVGEVVSRTWRTAAKMKDVRGPLVSEGDTKEKDNMRVKRYIAKYTINPAITHGMSHMIGQVAVGTLADLVLWKPENFGTKPEMVLKSGVIAWAQMGDANASIPTVQPFLSRPMWGSYPAAAALNSVSFVSSISIESGIIASYNLSKRFTAVKDCRKVTKMDMKHNTAMPRMRVDPETYAVHADGVLASVPPARELPLGRGYNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7K2</accession>
    <name>M5G7K2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_114546</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631039.1">
        <property type="nucleotide sequence ID" value="XM_040769843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7K2"/>
    <dbReference type="STRING" id="1858805.M5G7K2"/>
    <dbReference type="GeneID" id="63684905"/>
    <dbReference type="HOGENOM" id="CLU_1077776_0_0_1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28057" checksum="6B127F43EA382202" modified="2013-05-29" version="1">MPPPLSFERNGQRIFILNPPDDSTTPPPSATGTNFQDTDDGLLSSPTDTARDGEFFGSKDAARKIYQCDVCLKSFTTSGHLTRHARIHTGIKPHVCPYPGCDKDCSRMDNLIQHYRVHVPREDRGRGNSFIRTCMIDLMATKAGSPSQQGKVSVERSGNSLVARKTVDIDQSSNAARSPEEVTRRSSFASRSEDRVPFSPGSSRSPTLASPAESAMSGATAAVITSTNEEDAKLLVSLWQLPASPHKESFLRGNYASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G820</accession>
    <name>M5G820_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_19544</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I NDUFA13 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633250.1">
        <property type="nucleotide sequence ID" value="XM_040771558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G820"/>
    <dbReference type="STRING" id="1858805.M5G820"/>
    <dbReference type="GeneID" id="63686620"/>
    <dbReference type="HOGENOM" id="CLU_119720_1_0_1"/>
    <dbReference type="OMA" id="YGIREQH"/>
    <dbReference type="OrthoDB" id="3308at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009346">
        <property type="entry name" value="GRIM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06212">
        <property type="entry name" value="GRIM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU06356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="122" mass="14191" checksum="CAEC826ABC787E68" modified="2013-05-29" version="1">MSVPYRQDMPPTGGFEAIRYKRYLPYKGPSGAVIFGAFFLVSAYGLYRVGMGNREKRELLREKQWARIHLVPILMAEADRNLVRREYVALEREKELMKNVKGWQPGGKVYHSDKYIPPSIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G847</accession>
    <name>M5G847_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_67044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628939.1">
        <property type="nucleotide sequence ID" value="XM_040775834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G847"/>
    <dbReference type="STRING" id="1858805.M5G847"/>
    <dbReference type="GeneID" id="63690896"/>
    <dbReference type="HOGENOM" id="CLU_054590_1_0_1"/>
    <dbReference type="OMA" id="CATCFFP"/>
    <dbReference type="OrthoDB" id="58297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562:SF2">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="30398" checksum="C5153984501D4867" modified="2013-05-29" version="1">MLVTKSHVDVTHSLTGKPMRIFIIEPVLPEYPNAKFPGIVVFSEIYQVTGPVERFAGQIASQGYVVACPSVYHDFEGPEALPYDTEGTDRGNKYKIEKEIASYDEDRKLSVDLLVQHKRCNGRIGATGMCLGGHLAFRAAFDERVLASVCWFATDIHSATLGKGKSDDSLIKVRKGELNGKGELVMIFGKQDTHVPREGRDLVRKTLEDADVTVSWIEVQAQHAFVRDEQSKGRWDAALTRNLFGVMMEVFDRTVARDLGKRVGGKSEIEHVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G881</accession>
    <name>M5G881_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_95780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626860.1">
        <property type="nucleotide sequence ID" value="XM_040777318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G881"/>
    <dbReference type="STRING" id="1858805.M5G881"/>
    <dbReference type="GeneID" id="63692380"/>
    <dbReference type="HOGENOM" id="CLU_022453_3_0_1"/>
    <dbReference type="OMA" id="LFRSCEH"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="7">
        <location>
            <begin position="42"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="25561" checksum="85B3951FC9BCC934" modified="2013-05-29" version="1">MAPMTIDDYTWPPQDNGDKLPWPSPPPGRFLPVSLPNWDPTKIVSLDTQAVGAGHGGTIPQLSRVTLVDYRGQIMFDLWIRPQSPVTGPPRNQTMAPEGVEALGFEEVQSLVGEVLEDKVIVGHSLWESLSILGLSHPASLTRDVELYWPFRLRLGTREHVRLASLVWHFMRRHIQRARIDSLENARAQIDLYRSVEREWEGYLQHNLWPCVLPPERWARCYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8B3</accession>
    <name>M5G8B3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_55300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626895.1">
        <property type="nucleotide sequence ID" value="XM_040775311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8B3"/>
    <dbReference type="STRING" id="1858805.M5G8B3"/>
    <dbReference type="GeneID" id="63690373"/>
    <dbReference type="HOGENOM" id="CLU_047737_4_0_1"/>
    <dbReference type="OMA" id="WYSRDVA"/>
    <dbReference type="OrthoDB" id="10040024at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="35246" checksum="8C0C47122C9E9A71" modified="2013-05-29" version="1">MFFWVFWYSYPPHKQQQRDPQWDNRQPECILPQTVIIHSSRSSQSSSSSLTTTLSQSNSYIPPPPPPPRKPTFTARLRSSPAAMLLGIIPLLTLGLGFWQVYRLRWKLALIDELEDKLGREALWLPGRINVDKLPEFQYRRVLAQGTYLPSQTIYVGPRTYDGVHGYHAITPLARPGGSTIFINRGFVPKDFCPGGPKYAGSPLALERTGGEVTIEGLLRQSSTRGTFVPENEPEKGVYYWVDLPLLSERMGESAQPVLVDEVYEGHLGLVAEKLARGEPVGRKAKVEMRNQHAVYAATWCVPDWVNLSGTDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8D3</accession>
    <name>M5G8D3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_14114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631913.1">
        <property type="nucleotide sequence ID" value="XM_040771016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8D3"/>
    <dbReference type="GeneID" id="63686078"/>
    <dbReference type="HOGENOM" id="CLU_050410_1_0_1"/>
    <dbReference type="OMA" id="KNQGWNG"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00598">
        <property type="entry name" value="GH18_chitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067629" evidence="9">
        <location>
            <begin position="21"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="36"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="35054" checksum="D5E01F28B8F67477" modified="2013-05-29" version="1">MVSVSFVFLAAFGIVTGVLAAPVELIQKRQSAQAAPHWVAYSDKWVSGENGPPAPSVINGFNVFILSFLMTSGAADQALEWTTLDSATRASIKSEYANAGMKLLVSAFGSTDAPTSEGYNPTSLANTMAAWVKEYDLDGIDVDYEDFNAFNSGTNEAVTWLVTFTQALRAALPAGQYIITHARWEPGSLGSCIAVAPWFSKSQYPAGSYLDVNTQAGGDIDWYNIQFYNQGSTEYTTCAGLLTASSSSWPNTALFQINASGVSLNKLVIGKPANSGDASTGYMSTSTLASCVQQAQAQAQGWEAGVMTWEYPDAASAWIEAVRADSWPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K8</accession>
    <name>M5G8K8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_21918</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629074.1">
        <property type="nucleotide sequence ID" value="XM_040772604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8K8"/>
    <dbReference type="STRING" id="1858805.M5G8K8"/>
    <dbReference type="GeneID" id="63687666"/>
    <dbReference type="HOGENOM" id="CLU_002472_1_0_1"/>
    <dbReference type="OMA" id="TPMMAQY"/>
    <dbReference type="OrthoDB" id="121051at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="8">
        <location>
            <begin position="808"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="541"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="975" mass="109307" checksum="4022358F75E653B3" modified="2013-05-29" version="1">MASSLGPDSSSGEFSRGGGGSNQFLTAAELRAQTFRAQKKSQEGYFEFLKDVHDKTGKRPGEDGYDPRTIFIPKNAWASFTPFEKQFWEIKQNHYDTVLMFQKGKFYELYEQDAEIGHREFDLKLTDRVKMKMVGVPESSFNFWAAKFLAKGYKVGRVDQVETQLGAEMRVAKHGNSSGGSGKEIVRRELNKVLTNGTLVDPELMVDDEAGHCVSIKEGKNNTFGICTLDAATGEFNLCCFEDDACKTRLETVMRQLRPKEVVHCTDNLSISTIRLLRTVVPGSCLWTALKPSLESWSYERTLDELVNLYPATQNDSSSVIQGRDLSGLPPAIRTVVTEVTAVEALGGMIWYLGQLNVGKDLLTMRNFNIYDPMRRGMGLVLDGQTLAHIEVLVNSESTDEGTLLNLLNRCVTPFGKRLFRIWLCMPLREVKAINARLDAVDDLMSRPSFEATFGKLSRGLPDLERMVSRVHARTCKTKDFEKLIEAFRQVQRGFSDLAEEADDFSSRSIGDLLSSAPDLSPHLRHIQGMYHVKDDLLYPVQGADSDYEQVQAEIDRLEARLQEDLDSLKKKLNFSNLVYWHSPLGTKEIYLVEAPSSFKGIPKGWTKGGGTKAVHRWQVPDLMSTIRKLKEARETLKEVIKQYKLKLFNEFDQDRDIWLRAVRVVAELDCLFSLAKSSQALGEPSCRPQFVESDNAFLDFQQLRHPAFLTDRPFIPNDVKLGGDKEKIMLLTGPNMGGKSTLMRMTAAGVIMAQLGMYVPAAFAKLAPVDAILTRMGAYDNMFTNASTFKVELDECCKILRDATPRSLVILDELGRGTSTFDGMAIAGAVLHHLATHTLALSCFATHYSTLTEKKHPNIRNMHMGTTVDEHERQLVFLYKLIDGVATSSFGTHVASLAGVPTAVVERAEEISRDFAHEFETKMARRRISSVPIDLQADFAYLFKVGNRSVKLDEDAVRARGILTIMERTAAMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8W0</accession>
    <name>M5G8W0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aromatic compound dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_108936</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627085.1">
        <property type="nucleotide sequence ID" value="XM_040768769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8W0"/>
    <dbReference type="STRING" id="1858805.M5G8W0"/>
    <dbReference type="GeneID" id="63683831"/>
    <dbReference type="HOGENOM" id="CLU_636192_0_0_1"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="9">
        <location>
            <begin position="44"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="8">
        <location>
            <begin position="121"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="431" mass="46744" checksum="5E441649189F89CA" modified="2013-05-29" version="1">MSAAQRKAPSKAVQLAIDAGAPTIIDPSTLPDVTDISPETVMEMRHLHDYARETKLTTEEWITAIQFLTAMGQKCSPIRHEFILLSDVLGVSALVDSINHTRQPNATENTVLVDQQGPMASEGKGDPLLVTLRVLDTQGRPVPGARVEMWETDAEGFYDTQYEGRTGPDCRGRLNTQEDGVCEFWAVFPVAYPIPSDGPVGSLLRSLHTSWPSTPPMFLPAGDDPISQQQSSSTYQTTHHSSNSSVAASYSNSYAGNPYVPALGVYQEHLIAPIHPLEFGQAPQQQSPHSQSLHGLTPYQSYQSYQPGPSTAGPPSIWQSSQVPSTSRQTFPSLNTNPPYHPYSPYAHHPLGFSEAQRPQWDQNVNAFMGNPTTHTPSSGSCVACGTQTGDTGRCQNGNLHYVHRGGCLSHMEKACPVANLCEAAAIPETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9B9</accession>
    <name>M5G9B9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease</fullName>
            <ecNumber evidence="9">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_87053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase HII family. Eukaryotic subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="9"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631709.1">
        <property type="nucleotide sequence ID" value="XM_040776797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9B9"/>
    <dbReference type="STRING" id="1858805.M5G9B9"/>
    <dbReference type="GeneID" id="63691859"/>
    <dbReference type="HOGENOM" id="CLU_036532_0_1_1"/>
    <dbReference type="OMA" id="RYSWQTA"/>
    <dbReference type="OrthoDB" id="7462577at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07181">
        <property type="entry name" value="RNase_HII_eukaryota_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.460:FF:000001">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000016">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="entry name" value="Ribonuclease hii. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00729">
        <property type="entry name" value="ribonuclease HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF7">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-2" evidence="11">
        <location>
            <begin position="49"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="312" mass="33936" checksum="BCCFADD9444D6A4F" modified="2013-05-29" version="1">MEDSEREGGGNQQHPALHSPPSPLSQSYTHHSPLPSLAHQEDSNGEKTKFMVGIDEAGRGPALGPMVYAAAYCPVDWEQLSELGFNDSKVLTADTRTKLLGTLSAHPTHLGWSVQVLAPSSISQGMLARPPTNLNVQSQNATVHILRSLLQAGLNITQIFVDALGPSVPYQKYLQSLFPSAEVTVCPKADSIYEIVGAASVAAKTCRDAWMESWVWEEEGMPPGQELGSGYPSDPKTQAWIANRLEKTFGYPRLVRFSWAPIRLSMEKHGHVVKWMDDNQASVAKSFASATGRDKGRCGLAKDLGLRSVCDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9H3</accession>
    <name>M5G9H3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_115574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629406.1">
        <property type="nucleotide sequence ID" value="XM_040770033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9H3"/>
    <dbReference type="STRING" id="1858805.M5G9H3"/>
    <dbReference type="GeneID" id="63685095"/>
    <dbReference type="HOGENOM" id="CLU_037132_4_1_1"/>
    <dbReference type="OMA" id="KQVLRPW"/>
    <dbReference type="OrthoDB" id="1306014at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="38480" checksum="2FAB23183B43442A" modified="2013-05-29" version="1">MPKKATKLEKKEKKKKRMAIIRPWCWYCERDFEDVKVLMQHQKAKHFKCSHCPRRLNTAGGLAVHIQQVHKLEPDRIENALPGRDGYDVEIFGMEGIPAPDLADYKRRKEAEFGLAPGSTSVPAEAKRPKIDKRVLTQTELAQMLVAHKALMSGGDVPMTSGGALAAPAAVGAPVAFGAPPMPFPPGMPPPGFPLPPGMSVPPLSGVLPGMPPFPPVPGPLPAPGINGAPPASFLPPGVIPPPSLLLPGMTPNGPPSASLGLPLPPALSAPPSGSLQMSGSLPPQSLLPTSTPTFSPMQKVEYARQPEIKDGAKLLWADASLSPEENRAKAIKYSQPFGNAASEGDDIDGPRGVKRARAEDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9R0</accession>
    <name>M5G9R0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_80777</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627460.1">
        <property type="nucleotide sequence ID" value="XM_040776470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9R0"/>
    <dbReference type="STRING" id="1858805.M5G9R0"/>
    <dbReference type="GeneID" id="63691532"/>
    <dbReference type="HOGENOM" id="CLU_001666_8_3_1"/>
    <dbReference type="OMA" id="IMKGSRH"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="7">
        <location>
            <begin position="351"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="8">
        <location>
            <begin position="588"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="868" mass="96781" checksum="86CC26A8EDB8B947" modified="2013-05-29" version="1">MRHSAPSRHRHDWRQRAYSRLFAHHEKRVIKSIESNSKEKGKSKYKEIASAIAVFSPPPRVKRLGPPIPHTSATQPLGPEIEVYKTKFDELLKYEEATCADSFKERLEMWDLDKLKEEGYVLVGLRGFWRAYKKAGKPIAVFSRVEGDIGWNRFDAGSVVTVCRRHPLYEETIPGTVVQKTTSAIHVAFNDKTLFDDQETLLEEGVWRLDFGSNNINFARMRAAIEALAHNPAEHEFAAQGGDSEYILRGTFVRDALLRSFKPLAGMETPRAVETEISGRPVPERLAESAMAELPAEPRAGEVHPILSAFDPLPNRPPSGAFTHDQLIQSWARRYRRPNPIVVEGDPVLDLNETQTRAVALMLSKRLSLVQGPPGTGKTKTIIEAARLLKLHFEVPQPLLVATYTNVAVDNLVAGLAAAGLRPLRVGGEEYSQQPKLDKHRLEVKIAAHPLQKEVEKLEKAIDKLSDRRREAIDAAKPSKNEERIERAKNTHKEHLLRLKMKKFAIRNAMIHDIVSKADVVCTTCLTSANTALNVIDFPVVFLDEASMSTEPASLIPLMKGSRHVALIGDHKQLPPIITSAEAQAGGLSKSLFERLTEEGDTPSIMLDMQYRMHPSISRFPSAQFYNKTLRDGTVDHAGKVRPSLAPPKSTLLDDESVSELQTEKERLSVVFVDHAGSEAKKDRSRINAGEAQMVCSIVEELLYCNPSMTGDDIGIIAPYVAQIRLLDRLLKHDQEQAERFKSTLGEHRGLQMSNIEVKTVDGFEGREKEVIIFSTVRNNPQGAIGFLADGRRLNVGLTRARRALFVLGNAGTLKDGHGGFRGTGGVVLAGGGERVWKRYMEWLEKEQLIRRWAGGRFLPLAVGKTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAE5</accession>
    <name>M5GAE5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UROD/MetE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632209.1">
        <property type="nucleotide sequence ID" value="XM_040767821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAE5"/>
    <dbReference type="STRING" id="1858805.M5GAE5"/>
    <dbReference type="GeneID" id="63682883"/>
    <dbReference type="HOGENOM" id="CLU_058877_0_0_1"/>
    <dbReference type="OMA" id="HPMLDHF"/>
    <dbReference type="OrthoDB" id="7772923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="357" mass="40806" checksum="6370653FD32097B0" modified="2013-05-29" version="1">MAPPPPFRAEHIGSFKRPKHLIDARNKADKGQLSQADLILIEDAEIQRIVQLQQNYGYKAITDGEFRRYGFYDGFFDRLDGMVSVQNADPEIFMDYVPDVKAFKIKDFKGGQTYICTGKIRRTQPLYVPSFTALANMVAPEEVKNIKLTVAAPEWYHLRHSAKYAYSKEVYKNDAEYFADIAKAYQEELDALYEAGCRNIYYIALINDCISKRKPDMSVGVHLCRGNFRGIYFAEGSYDTIAARLFNELNVDFYYLEFDSPRAGGFEPLAHLPKHKQVILGLISSKDPTLEDKSMIIGRIHDAAKYMNDPNLERICLSPQCGFASHIDGNNVTKEDMENKLRLVSEIAQEVFRTTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAP5</accession>
    <name>M5GAP5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carboxypeptidase C</fullName>
            <ecNumber evidence="2">3.4.16.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_115312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.5" evidence="2"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629931.1">
        <property type="nucleotide sequence ID" value="XM_040769978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAP5"/>
    <dbReference type="GeneID" id="63685040"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_0_1"/>
    <dbReference type="OMA" id="AQDANCA"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="515" mass="57973" checksum="A9A082BA0289C3FF" modified="2013-05-29" version="1">MRPFRSPLREKAHLLPATTFVEGIPSNGYRKRQERKILKLVLTAAFIFSLMQLWRLSLWRQRTDILPTPATPEPAEFYSAVRTTKICTNEDRSALGYAGYIALDDDKPDNQRRSFFWLFEAQNDAQNAPVILTIGGGPGTTGLANPLFGQSHCLVAPNGTTKANPVPWSEHYNLLALDHPIGVGFSYGAGVNNSRSAAYDVYDFLQKFFRLYPNLRPNKFVVSSGSYGGIYVPHIAHVIHEENKKVAAGRGQPGAKHINLDSLMISNPLSDFEMHYRWLLQQRCYYTSIYNATQCAEFYEQLPGCLDAISYALSNSTAANRNQAEVTCAPINSGDTHGWDLQDVRLYCGGNTDDIGRCYPEFPWLEEFLNSTKTREELGIPKHVSYQALSETVFREFWAEGDLVQRAQLLYIPLLEDGIRVLHYVGYRDANCAWPGIIAFLKLLKSPFQERFLNTPDVPWPTEDVATVRAVGPGAGNFTYILVKEAGHLVEKNQPALVKSIVEHWIENKAFVEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB03</accession>
    <name>M5GB03_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_112868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632983.1">
        <property type="nucleotide sequence ID" value="XM_040769525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB03"/>
    <dbReference type="GeneID" id="63684587"/>
    <dbReference type="HOGENOM" id="CLU_015679_0_0_1"/>
    <dbReference type="OMA" id="CELKQRQ"/>
    <dbReference type="OrthoDB" id="16772at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="114"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="462" mass="50862" checksum="A7A8DF52D16F97A2" modified="2013-05-29" version="1">MLKPRRSSATQRPPNPSPTCIADHISAAAATDHTPVASTSAGTGQARNRDGDTSGKGTPKGKGPAKGAPEKNDNTTPGRKSLHTMECSTCERSQRRFFCPTCVANHIRDFRLSQSRVEAEKQRLQGVVQQLLDKLEPRRTEKATRTLLIDRTREIKREVERLRHRSAELKENVRLRQEDLRQRRERLQRAQQLVSSPLTFTPLTAAQSRLDALSDRLALARRGLALLLMEVFDLRQTTTGEATIVSLPFPKPGDHRHTKPEQLNGVLVHTLHLLHLLAYYLGVKLPFVISWSGGRFLVGKPTIRASSGNSEDGDWVRWTVKQPLYISAADAARYAGAGAVPSSFTTALSMLAFNVLYLMHTQGLSVPGDGPSPATPPPPIRNGENQLPPRVLNDLICLCIPDSLGRRSHATRPHLPPPTHGLGLTFARVLEAAKEADGSKRAEELRKAEEGDADWDIIDDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB53</accession>
    <name>M5GB53_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_106406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630136.1">
        <property type="nucleotide sequence ID" value="XM_040768263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB53"/>
    <dbReference type="STRING" id="1858805.M5GB53"/>
    <dbReference type="GeneID" id="63683325"/>
    <dbReference type="HOGENOM" id="CLU_154777_1_0_1"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="13306" checksum="BD404D1F1752C728" modified="2013-05-29" version="1">MPVVFSPLQKQVLSLYRTALRSIRQKPPSAQAAFRKLYRHAFRTRAREYSKRDIAAVEHLLRQGRRWVEVMQGQGVRGVAVGLEVERWWNEEGRRDWWTAREEKAEEEDGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB80</accession>
    <name>M5GB80_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRAPP trafficking subunit Trs65-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630181.1">
        <property type="nucleotide sequence ID" value="XM_040770014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB80"/>
    <dbReference type="STRING" id="1858805.M5GB80"/>
    <dbReference type="GeneID" id="63685076"/>
    <dbReference type="HOGENOM" id="CLU_006972_0_0_1"/>
    <dbReference type="OMA" id="FNQSSWT"/>
    <dbReference type="OrthoDB" id="24630at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024662">
        <property type="entry name" value="Trs65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159:SF1">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="645"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="911" mass="96650" checksum="5952C5692B91E70E" modified="2013-05-29" version="1">MTSIEQLFGRSSVDIFIPSSELSLTTITDYAGWANRIQSRKFAFYDEHLPLILSLRIPLSSSSSDTPPTNVLTLLSRTQLTLEAAYIAPTHPSTPLNPHPPSARPSSALSLPPSRAASLRPSALSVPPQTPVPTPGTADWDRKFARAEGVVMGTFVWGEGKEGKDGKEEFRLLWSERDKAWIALFTMQVTISYLRTRSTDPLLCLTCSATLRDKPLPLTPARKPLHSLSPPSLPSEPPTPSSGSSDLPPSSSEEEEEAPRFEEVNLLDGLLRPLPDLELPSTRLAQTLRRELFSLPQLESPPSSAVPSTAPTPTPTPYAYAHAHARARSVPAIMRKAFRRVLPVVGGLKVRMRAAFLPRPSGDGHGPHQPSDADAEEDDDQVGEEGGENRKCVLCVEVENSGEGYSFELQQVDVLLSGGDTRTLLLSWDPAQSSGGLFPLRLKAQDQYNLLYDVRFTPWTAAGTAAGTAAGTGTGMGAGAAAGQGKSRPAQRSVSITVLGRAFLPVPSSPRTPTLARPNGASAGAGAGAGAGAGAGKVPEVEYVTDSFPSTWNCMIDVTPTQPSARGGETFPPPTATSAPGAGAGAGAGQGQGTTPNPYGTNANHHLSPIASPLATEQDKRATLAALPLPPVLPSAPSRRPPPRSHTLPSLSSSLSLNTNLPRSPSSSSPKNAPRASLMTLLGPNGVPVVVPSPSAGSPRRSAGQRPPATPVYPPQSATRERNRVSFPPGNVSPSPGMGIPAPTSVYPSQVQVQVLSQPQMQMQVPTEPVLVSIALQYPALVVQDTLRLLDMFNLEVFVFNQSSSVRRLVVSCPPWRPIPGSTGDDQVQNSRAAFIPLENSKPLGPLQPHTCQSVQLPFLALRAGVHVVDMLELRDEDTGYVLCLRQVAVVVVREMGEVVKGEKVKEVLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBE1</accession>
    <name>M5GBE1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_75019</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632584.1">
        <property type="nucleotide sequence ID" value="XM_040776103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBE1"/>
    <dbReference type="STRING" id="1858805.M5GBE1"/>
    <dbReference type="GeneID" id="63691165"/>
    <dbReference type="HOGENOM" id="CLU_548622_0_0_1"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="148"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="306"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="55863" checksum="B72B98B014F0FC8A" modified="2013-05-29" version="1">MDQSPPAPAPPRQTQTQTQTFSLELEPELLTLLAERDREQRQRANSLPSRPRKGTFSANANAPSNRPAKRRSSLDPSAPEFTPSSLSLALSLTRSISPPTLSPSISNSTLSLSPPDSPTDPRIPFPLPPFADPLASEHKIFRRQPYDAFLLLDVEATCDEGVGFDYPNEIIEWPVVLMRWNEMDTSGRMASLTPFAEFRSFVRPTWATQLTPFCTSLTGITQSHINNAPTFPEVLAQFREFLVLHGLLDPETDEQLVRYTFVTDGPWDLRDFLVKQCWLSDIPVPAWVGQEVVDVRQLVRVALRTFDETDPDTEPEPEPEPEPAQPEGEPERERERGTKHTGLSLPCQLHNLSLPPFQGRQHSGIDDARNVARVLQELARRGWVVERNSSLMLGEWGLGWDWMGPTRGSVVRGEKWKGWAPGREDWEQGEPVDSTANPDPVDVSDDNLLLLDSHSPQDLLQDRQENQRQRLRMLLSPIPESAPPTPFAPSPELVETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBG0</accession>
    <name>M5GBG0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Imprinted and ancient</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_86056</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633183.1">
        <property type="nucleotide sequence ID" value="XM_040776758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBG0"/>
    <dbReference type="STRING" id="1858805.M5GBG0"/>
    <dbReference type="GeneID" id="63691820"/>
    <dbReference type="HOGENOM" id="CLU_045276_0_0_1"/>
    <dbReference type="OMA" id="INAWRCR"/>
    <dbReference type="OrthoDB" id="69641at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11605">
        <property type="entry name" value="RWD_DRWD_ELF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF24">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="RWD" evidence="9">
        <location>
            <begin position="34"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="38653" checksum="91D83344D3FD59FB" modified="2013-05-29" version="1">MEHTEEEYRNYASEIAVFISQVYEAEPEQPEVMAELEALQSIYGENSIRTWKGNGNGNGAKEWAPGEAIRYEVVTSLSPPYEDTSLRLLVTLPQTYPHSTPPQLQLLSKYIGPYPVTSQLFGGVLRTYLSQAHGVEFRLGEVAVFDGVESTKERVGRWFEEEKGRGEALAVQREMERERQTGSETPKAREEPPAPRVPMEVQVTAELPDGIELIVAEPIIDRKSVFVGRACKITHPSQVPPVIAYLMSDRRIARAAHPVIHAWRCQVGNVLHQDNDDDGESAAGGRIAHLLQILVYVLVIVTRYFGGILLGADRFKHINQAARDALELGGFLDTDDHATAKSRKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBR4</accession>
    <name>M5GBR4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoenolpyruvate/pyruvate domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_95078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628355.1">
        <property type="nucleotide sequence ID" value="XM_040777269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBR4"/>
    <dbReference type="STRING" id="1858805.M5GBR4"/>
    <dbReference type="GeneID" id="63692331"/>
    <dbReference type="HOGENOM" id="CLU_059964_3_0_1"/>
    <dbReference type="OMA" id="WNRVDDY"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="29587" checksum="CEB89BD140E37039" modified="2013-05-29" version="1">MAGQMNNKLLQTLRAGKQTFGIWQMINSPAISRTLSLLGPDWICVDCEHGNIDDAGMHEAIHNIRAPVTPLVRIPDNQNVYVKRALDAGAQGLCVPMVNTVEQAKYLVESVYFPPQGKRGLGSPYAMASYASNGVAPSLGDYFFNANAQILLMVQIETEEAVKNVDEIAALEGVHMLMVGPFDLSNSLGVPLVRGETDKLKEAIGKIQASAEKHGKWCGIYSTSPEDAARRAREGWHFIALGSEMSFLQTGIVDGLRIARGGETKQSKEVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBS6</accession>
    <name>M5GBS6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_104381</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632784.1">
        <property type="nucleotide sequence ID" value="XM_040767921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBS6"/>
    <dbReference type="GeneID" id="63682983"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OMA" id="VDLQMKE"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF70">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="52759" checksum="9B34B6D0BF17E84D" modified="2013-05-29" version="1">MANETSARRARASWKISLGLINTLSNYTNYYGLPATGSAGTGIVFAIFNVGQIAGALFIWLADWTGRKIPIFIGCVGVIIGTIITATAPTLGVFVGGRFLLSFFCTIATTSAPLYMIEIAPPLYRGTIAGLYNTLWYMGSIIATCAVFGAHRNLADRGELDWRLPLWLQMLCPGIVLLGIFFCPESPRWLIGKGRVEEARALLVKYHANGEENHPLVELEMQEMSEALAKEGLTSWRNLFDLRVLFNTPGWRYRIMLNIAFAWFGQFAGNNVISYYLPSMLRRIGVTDTDTQLLLNIIYAIVGWVFATGGARFLDTVGRRPMFLFSVGAMAICLAIVAGTAAGFVQTGSTSCSYASIFFVYLFGATFAISLTPMQPIYPGEVLTNDMRAKGMGVMQISSGVASFINTFAAPVVLNNFYAFFAFFDVFEFLFIYFLFVETKGRTLEELEVVFNSPNPRKASLAFAESSKRKEKGGVEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBT0</accession>
    <name>M5GBT0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_46127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632789.1">
        <property type="nucleotide sequence ID" value="XM_040774683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBT0"/>
    <dbReference type="STRING" id="1858805.M5GBT0"/>
    <dbReference type="GeneID" id="63689745"/>
    <dbReference type="HOGENOM" id="CLU_052861_1_0_1"/>
    <dbReference type="OMA" id="FVAWDDT"/>
    <dbReference type="OrthoDB" id="16729at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="23643" checksum="C31B5E66F5E4FB25" modified="2013-05-29" version="1">MTPEVSLKLRLRWLEALVTGTSGRRFPPNRQVKLPTHALVREVDEAQERLAAICKDNLPMKRFISCYELYASLLPPPEDQPAPPDSLTPDEAVAYFAEAEVDVRSADRDMADIKELERKGVVNAGRLSEHDALKPRLRELMQHHLRNRRKFADIERRLMDLLQGYAASIDSLSEKFVDLNEIMADAEIQVSRLEREKAERERRGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCB4</accession>
    <name>M5GCB4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_44458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633568.1">
        <property type="nucleotide sequence ID" value="XM_040774577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCB4"/>
    <dbReference type="STRING" id="1858805.M5GCB4"/>
    <dbReference type="GeneID" id="63689639"/>
    <dbReference type="HOGENOM" id="CLU_013485_1_0_1"/>
    <dbReference type="OMA" id="ICQIRAI"/>
    <dbReference type="OrthoDB" id="2020758at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="58"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="538"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="590" mass="64834" checksum="7B79E743B33B56E8" modified="2013-05-29" version="1">MVLSLFGWGSYARPESGEAIELEPKGKVVRTRAEQLKRLGNQEDSPAGLCSQSDLLYPGLVNISGTYCFLNAVLQALASCVYLQPFLDQLQERAEELDVPTPVIDALRDILQKLDAPGTRFQALRPSAIIEALANSSQQNHNTLFLSREHQDAQELFQLVSSVLQEETNAVQQEAIKDLGLKGLHSLKPASSGAVDLSTPFEGLSANRRTCGDCGYTEAVMHFPFDNITLALPAQSSCGLEECLLDYTRVERLTDCVCRKCSMLATLWKLGADSQRLADRGEERSPSKKKRGKEAKKLEGRVKEAIDGGRVEEDIKGVKVEKVYSSSSSKQTMIARPPPILVLHVNRSTYFGHGYAGRNSCRVYFPELLDLTPFTTGGELNLLPNVSLSAPSILSLPALLANTRAAVLYRLDAVVCHYGTHSYGHYVAFRRKPAPPNTKVRWAPPTLSCPLDCICEDCRVYGPVRDQYSGRYAGWLRMSDDNVEEVGLSAVLRETAGTFMLFYERIQMPPNPVAVQKTGEKADKTSGRIVHSVQIRNGRRTENGHKLELAAESSMDIDSSSREGSETPEPAPSEGTATVVGEERQDVGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCQ7</accession>
    <name>M5GCQ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methanol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_79611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628815.1">
        <property type="nucleotide sequence ID" value="XM_040776404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCQ7"/>
    <dbReference type="STRING" id="1858805.M5GCQ7"/>
    <dbReference type="GeneID" id="63691466"/>
    <dbReference type="HOGENOM" id="CLU_002865_5_1_1"/>
    <dbReference type="OMA" id="SWPTPHF"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF78">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="559"/>
            <end position="560"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="653" mass="72042" checksum="19D65DE4D3C2F1F1" modified="2013-05-29" version="1">MGQVKEVDVIVCGGGPAGCVVAGRLAFADPNLQVMLIEAGANNKDDPWVYRPGVYVRNMQQNGINDKATFYVDTKESSYLRGRQSIVPCANILGGGSSINFQMYTRASASDWDDFKTDGWKAKDLLPLMKRLENYQKPSNNNTHGYDGPIAISNGGQITPLAQDFLRASEAIGVPFSDDIQDLDTSHGAEIWAKYINRHTGRRSDAATAYVHSVMDVQNNLHLRTNSKVARVIFEGNKAVGVAYVPAKGRTHLNEVHETIVRARKCVVISSGTLGTPQILERSGVGDAKLLKSLNIPIVSDLPGVGEQYQDHYTTLTLYRVSNESLTTDDFLRGDKEAQDKLFAQWEHSPEKALLSSNAIDAGFKIRPTAEELKEMGPEFNALWDKYFKDKPDKPVMFGSIVSGAYADHTLLPPGKYITMFQYLEYPASRGKIHIQSSNPYHVPNFDSGFLNKKADFAPIRWSYKKTREVARRMDAFRGELTSHHPHFHPASPAAVKDIDIETAKQIYPDGLTVGIHMGTWHRPGKPYDASKVHEDIKYTPEDDEAIDNWIADHVETTWHSLGTCAMKPREQGGIVDGRLNVYGTTNLKCADLSICPDNLGTNTYSSALLVGEKAADLLAEDLGLKLRIPHAPVPHAPLPKGKASAALPRYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCW4</accession>
    <name>M5GCW4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633359.1">
        <property type="nucleotide sequence ID" value="XM_040769580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCW4"/>
    <dbReference type="STRING" id="1858805.M5GCW4"/>
    <dbReference type="GeneID" id="63684642"/>
    <dbReference type="HOGENOM" id="CLU_637911_0_0_1"/>
    <dbReference type="OMA" id="REICRNR"/>
    <dbReference type="OrthoDB" id="3349400at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38209" checksum="FB9D95AE8FFBD750" modified="2013-05-29" version="1">MCIPADPTALATQACVLCSRVRQQPACHHLRGICTQRQNHPGLNNISYFTNAEYDVFNGCGFCKFAQALAAGKVPHGKNRGFPGCCRPPTDADTDIIPDACWPAVAAFWKVPIPEKVLRRISPRSLQQLQLRKEDGGSPTTSKLSLKTAGSMPGDRKSSPPTPGSRNSKLTNSPTDTVRRSVDPSRPPIPSSIASPTRSSQPRSGGTNGTPSRIHPSQVHITIDQSNSPPPPPPPPKPSPATDDLTKSFARINVSRSGSYDPSKRNSIGSMSSLSEATCSDFTDYLSDASDQRMQKEVEERVTQKWEEREFFQARSKVAHMDLQPPDFWAGRADRRYAEPVQVAGGRRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCZ1</accession>
    <name>M5GCZ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pH-response regulator protein palC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631031.1">
        <property type="nucleotide sequence ID" value="XM_040772068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCZ1"/>
    <dbReference type="STRING" id="1858805.M5GCZ1"/>
    <dbReference type="GeneID" id="63687130"/>
    <dbReference type="HOGENOM" id="CLU_027723_0_0_1"/>
    <dbReference type="OMA" id="PNDKEWM"/>
    <dbReference type="OrthoDB" id="10266451at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071467">
        <property type="term" value="P:cellular response to pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037505">
        <property type="entry name" value="pH-resp_palC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="3">
        <location>
            <begin position="2"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="430" mass="47152" checksum="F5E974A8E1FB7CA7" modified="2013-05-29" version="1">MSVYYYELPTTGAVTFGDLLDDRTGTHTEDVSNTSSSRAQVRGILKETKRMGAEKDYLRVIKVVEDYLPHLGGIMDCVFAEELMPYSEPKFSWRSTLSSHLLKNSPRVEGTGFYYELCFCLLTYAYGLCDLAHATVASLGNYEQEGYLSEAERKEKDEQLNFAARTLCKAAGIFKSIPDAILPQWAKVNSASSKGKDRPPDLSPEVLATLPKVAMADANGLAIRKLMSRSVAESIAVPGAPLPKSHPAPSLLGKLWIHVHTEYATARSLVNKSTALGVRDEVDADLRKYLEHGAAHALAMAFKWFGIDAGERGRNGVAMAFLTAAKEDLAELKDVKGTSALESKSQQKEAIAEEIDSVTQWFGRYKVANDSITFQDVPSKAQVRAMIPDGVAVLKLQLFSLPKAAFGPTSRMGESTVEEQADYVRAGQYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEI3</accession>
    <name>M5GEI3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632341.1">
        <property type="nucleotide sequence ID" value="XM_040767845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEI3"/>
    <dbReference type="GeneID" id="63682907"/>
    <dbReference type="HOGENOM" id="CLU_657239_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="418" mass="46208" checksum="E8DC0503CA714188" modified="2013-05-29" version="1">MAPSSTSAASSKKPLSTKTKPKASLIKKPSTTDMKKGSRSQKASGKKTQSKELTPELEPVANHPESIAKLVSMKVMPSKKASAPPSKTLTLKLRVSLTCSSRRVKQELEAHKEPEEGQEVKAVTKWHKVEEEDQVMDEIIVKETTLEPAGSDEEQEPPSKDLPEILAMVPAPNEDPEAWQKVSRVSKFWVELIKWITKNNSKEQWQFVPPMAASYMGPAFKVQWYAYMGKQITVKLATCGGPVYLLFEEWVEMPRMAVVGRDDKPPFDTWVLRHQADHKAVHASDKEPDENLEATIEAKQGVWNVLPEIKKTQHLNIVQMYQMAGIEGSPVLPDLKVVTPVPLPKKATLLRVSISATASLPSLPPKSLSVVELMPAPNNNKKKTGKTPKNKLSEELLALAAKAKPDLLSASDGVLWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEK9</accession>
    <name>M5GEK9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630247.1">
        <property type="nucleotide sequence ID" value="XM_040772440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEK9"/>
    <dbReference type="STRING" id="1858805.M5GEK9"/>
    <dbReference type="GeneID" id="63687502"/>
    <dbReference type="HOGENOM" id="CLU_036920_0_0_1"/>
    <dbReference type="OMA" id="VNDTWFG"/>
    <dbReference type="OrthoDB" id="2278929at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="547" mass="56819" checksum="B9F71972813E55D1" modified="2013-05-29" version="1">MAFPHPPLATPTPPPIVYTNHQPHRNKPQPPPPPDHTYERVDKLIKQRRAVLRGYDQQGHEVVGPDLDLEERTELVGRQAWNTSYPSCDDVGNSILSCYPIQGLTLVESDWTKFIWNLRQPQFIGAVTVDVYLFHADSDLMALSFPGQQNAAGQIGVQVNDTWWGPRGDTFDGENVTFPYYFVVVPGGTVLTGGESRLATFLAIQTATPGTLASVSSASLASIAAQASESSASVLSVESVASVSLTSLALASASSASISSQSIESILSFSSALPTLSALSVASPAVFSSLSVESIASAASLASVSQSSVAFTRTSNGTVPTGDLQGGLGNGSGTPAWTIAVPTVLGFLALLFFCALLFLASRWFRWRRAELARRGSMGSQSPMMANMPGEPASKPPKPPSPALGGDAAGATLSRDGSSATTRPQVMTRSAEGNPDITLSGGPGDLSRSASGASPFSGVDAAIMARAFREALNKPDFSSPVEEGSSGPGSQENAQNGADSPGGSKDGHTTEEGFSRVGQIVQEEGGRVGRVGQQSVRVQGPGASNGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEM6</accession>
    <name>M5GEM6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_19989</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632436.1">
        <property type="nucleotide sequence ID" value="XM_040771753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEM6"/>
    <dbReference type="STRING" id="1858805.M5GEM6"/>
    <dbReference type="GeneID" id="63686815"/>
    <dbReference type="HOGENOM" id="CLU_041802_1_1_1"/>
    <dbReference type="OMA" id="ASYMARY"/>
    <dbReference type="OrthoDB" id="5852090at2759"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="13">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="14">
        <location>
            <begin position="128"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="15">
        <location>
            <begin position="250"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU05542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="393" mass="42690" checksum="1A06D456871B34C6" modified="2013-05-29" version="1">MASNGHVAASALAPGHFLFTSESVGEGHPDKIADQVSDAILDACLAGDPFSKVACETATKTGMIMVFGEITTKTQLDYQQIIRDTIRKIGYDHSEKGFDYKTCNILVAIEQQSPDIAQGLDHGSLENIGAGDQGIMFGYATDETPEYMPLTIMLAHKLNHAMSVARRDGSLPWLRPDSKTQVTIEYKKDGGATIPLRVDTIVISTQHAEEISTEDLRKEILEKIVKATIPAKLLDERTVYHIQPSGRFVIGGPQGDAGLTGRKIIVDSYGGWGAHGGGAFSGKDWSKVDRSAAYTARWIAKSLVAAGLARRALVQLSYAIGVAEPLSVFVDSYGTGKVSDEELTQVIRKNWDLRPGVIVKDLGLQKPQYLATASYGHFGNPAYSWEKPKQLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GES9</accession>
    <name>M5GES9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632546.1">
        <property type="nucleotide sequence ID" value="XM_040771785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GES9"/>
    <dbReference type="STRING" id="1858805.M5GES9"/>
    <dbReference type="GeneID" id="63686847"/>
    <dbReference type="HOGENOM" id="CLU_665673_0_0_1"/>
    <dbReference type="OMA" id="CATSCIV"/>
    <dbReference type="OrthoDB" id="3363625at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067720" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="40787" checksum="E5C643EE26061657" modified="2013-05-29" version="1">MHFSLAALFLALPAIVNAIPSHKYDARFAALTVKHAQVAQRMANPLAGRMELGSRQSSCTTQCSSTADKNGITTYNACSSTDPVCICDALESLSATCLTCVLPAAGLSASQFSEICGNGATTTQCNSQCSDATDTAANQAADLCTTSSIEDPCVCSALNKMTSACLNCLLQISGISNTQFSQACAAGGSAGGSSGSPVGSQPTGGSTSCTVTACTSVSDQSGISQGADCSSTDVGCQCASLGKLSNTCLSCVLSSSGLTNQEYQAQCAASGSATATATTTTTAAPFQPTSSSSGGFSSPSCNSSCASSADQAAISRGNVCSSTDVLCACTAFNSMDSACLTCILSSNGLTQNDLTSQCAAASSQASVSSTAKPTGSNLPNTQNPTSGALAGFSIGIEGILGAVSIALGAMIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEY6</accession>
    <name>M5GEY6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Growth factor receptor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_62493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632711.1">
        <property type="nucleotide sequence ID" value="XM_040775699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEY6"/>
    <dbReference type="STRING" id="1858805.M5GEY6"/>
    <dbReference type="GeneID" id="63690761"/>
    <dbReference type="HOGENOM" id="CLU_010013_0_0_1"/>
    <dbReference type="OrthoDB" id="18487at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001368">
        <property type="entry name" value="TNFR/NGFR_Cys_rich_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15332">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15332:SF175">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50050">
        <property type="entry name" value="TNFR_NGFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="73"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="7">
        <location>
            <begin position="178"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="TNFR-Cys" evidence="3">
        <location>
            <begin position="178"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="640"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="679"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="679"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="785"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="805" mass="83721" checksum="8FA3764951679D68" modified="2013-05-29" version="1">MNPIAPAPNTSFERPNVTQINLGSIVMGSGAWVAFESQVGNLNQRTIIWETVPDMGELPSGAIGQGLTLLDLEYGTCSPACAGAGVCTSTGVCACPVGFTGASCETCQSSFFGPNCDACPAGCSACDDGTTGSGKCLSAPAVNPSASCNCLNGVCTSTGTCQCNAGWATGANGTACSTCATGFFLDAAGQCEICKLSCAACASGTGICTSCQPGFSVSPTDNTVCVPNTQLAAATTCPDGQYWSGSGCAFCSPVCQTCNGPLSINCIACGVGRFSLNGTCVNVGSDGTCTPPDASSPATLVANNGKNECDACPPKCTKCGIPGFNVASPFSSVQCTNCLPGFVLSQGQCVSQCPTGTFVSPTDNLTCAACDSTCSTCAGSATYCLTCSQSSQFALNGTCSSSCPPGTFASSGACLPCHSDCATCSGSSFSQCLSCAASRPVMSGAGRCLPTCGQTQYYDSATSSCQPCDPSCSSCYAPGSSSCLACADKTKVLSAGSCGSVSCSSNSTVVAALGLCLSELVTVAPSNTTTPDTPQIGTTPDGSQTVTTVNTQSLAWWQILLMALGGAFVLLLLTMIWRRYARRRRAQETRDFAHDMDRKRWHHRLQDMLFLRREKVPMQDVRPLYRERIDDWELRSLTSGGRSGANVSPRRSNRSETQRDSWDSISTFQIRGATPHADRFEYRDLEGSVRSKRSRGEPREPIRDRELQRASAATSSYYAPTRRTASPPVVPPLPERERSTTPFSIPRKAPRYPSGFGPDAPPARNVDLFAPLEEDGAHGPPGSYLTPNLTGSSGNSNNPFRAKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF72</accession>
    <name>M5GF72_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_97650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632911.1">
        <property type="nucleotide sequence ID" value="XM_040777471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF72"/>
    <dbReference type="GeneID" id="63692533"/>
    <dbReference type="HOGENOM" id="CLU_284411_0_0_1"/>
    <dbReference type="OrthoDB" id="10688113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
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        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="746"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1092" mass="116302" checksum="AB5268F8CFDCDA47" modified="2013-05-29" version="1">MPYIASVVQLLKTREAGFHRWLFMTPPVVVGRGDDGGRRKARQSTLPDRSKQTMPFRRGDVIVLDCSEDERPPSPCEEMYRSPSAWAVPVDLTSSPSELWLSLPSRSEPSTSQSTAVDDFNPASLLDPQFVALFNQCANNLPPSQPGPSISDLPTPPSSSPTDAPSNGPSDPPSVAPSSLSSSSPYPPSNSSSDGPVTPNPNPPVSEPLILGGLSTFNKGSHSMAASTMARRLDVVSPGAPSPDGFRSLLTSYTNIDPNTPGGPGATPQASTSSEAACAPKGKSPLREKSVGSRRPSEAPPSATAQAWTKAATFIMHSKPEDAAANMYSFIRTETAMAELRSQAQSRSLGRTLAAHTPKPMPWQVPSSSVLGLVMPTPVASSPSPRAGVQRAPRKSGSGGNDSHVEILTPSSPMLPTRDQNLTSSPSSMLPSQASHAQSSSSQPPRTMGGADVQCQSPDSPPEPSSSTRPPPAQSAEQRPVASDSQKTSTPKRPRHTEDVAIVPDPEQLTTPTERITRGVFEFQSNPATKEEWDRAVMEYVIQCREGKFTMYHTKGVHEFPPKDLWALPELVVNGSLHKFLVTTARILQTCILSLPDYILSNGKKTKWDWRGQMRQHLCKLSDGFYRVGDGSTTYSQLHRGLPHAFSLAFSLTEHGEVSEGDRAESGPPGASDERPAKKPWTETEGPDGQDTSPATPNEIQAGSSNPPRRGRPPKGRQSSTAVKSRSSGAHTGNAEPSVSQGSTHQQAEASSSSGPSQSTATTPDSQSQPTPSSDSSTRVASSGGIITPDYSGYVYDPSKPPPPFSSSALPPEWEGLNSTEALDALFPGGFQCSTDHLGFISVAFDTPMTMAMNNLPAPAGLGSQPSTPQRPTVVPAPSPSVSHARWGNDPSNAERMAGFLDDISHFAEEIGAVDENGNPSFAWEEPPLRDEFGYSTFPIDTNIIQKSGSATAIPMTSPVPAPAMRPNMYGVDQEDLSVAAPTAQSDRAARGSIYSEAGPSTIPVNRVPSPISCSDSAPRRGSRGKAAQRRKPNYEGFTRLSAKRNIGALVTAHANRTIAAAEERQARYSQVDERTQRASGMALPSYLRNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFM9</accession>
    <name>M5GFM9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631147.1">
        <property type="nucleotide sequence ID" value="XM_040772105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFM9"/>
    <dbReference type="GeneID" id="63687167"/>
    <dbReference type="HOGENOM" id="CLU_2073060_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="12433" checksum="E093E86AC80BCEDB" modified="2013-05-29" version="1">MQCATAHAALQDSIIRARERSLISRTLPTPPQTQQQTATSPGSQRRPASPITRANDSNQARQQDQRPDLERQGLPSLSSVLRSLTSNEVNALDAADAGGPSSGVGRTTCAQGSPKTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFN8</accession>
    <name>M5GFN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_87516</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631172.1">
        <property type="nucleotide sequence ID" value="XM_040776813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFN8"/>
    <dbReference type="STRING" id="1858805.M5GFN8"/>
    <dbReference type="GeneID" id="63691875"/>
    <dbReference type="HOGENOM" id="CLU_019713_0_0_1"/>
    <dbReference type="OMA" id="YRQMQEY"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="746"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="198"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="618"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU04278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="799" mass="92218" checksum="FCF96DAC50B93468" modified="2013-05-29" version="1">METIKRPLEEDSMTASPFPKRRVLSAGDGSPVPVAVDNHGLDVELFQKEALWRQMRQYSRDKDRAERKVVELRHRQESTEAAMAAMEATWIHLLDVIQERVGTGKDKYTPETLLRLDRYATMENVANQFKTQLADRSSSTIALVDQLVNPEVKLETDANRSWQQDARRAREQADVTGAELQLLRNRLVQAETDLEKYKEELSQSEKRVDRSRSKTVQAMESKEAKHEEETPKASTPDETKPQEEQEDVPMEPAEPNPPLTNGHVPAEDKENWELRAKERESELQKVSEEQMQLREEIRRLGDMVGFPSPEAITSSHTYLALLAEAKEWRSQAEEAQSFTKPLLERLEKLMSERTEFHAKTEEEYKKRTDELELVIERRQHDYARLRVKWEEIFAEKESLKNREMERQRSTSELKTLVTSCEQRINILQSEVKRLRARLAAQVGDADLLAFLIGSGPDAFSQQETTKQLLEARKKIETLETQASMDQKSFQDTLDKARKFDSLFGADASISLDQKTVASKLAATEEELRKARLKMRDDEVTTDALYSEIDRISAAWDSLEKQNKSKTFEMVDFEDKIRKLANEKAQEQSKYFAEKKNLKEAVNQYDSAIKTNAKQKLAIDHHKEIEKNLEQQLAQQQLATTKVEAALYDLQTQFRSRETEIAKSKGMNAELERLNNRLQHQNKDGGVMFLKQHEELRKAREDLKVAQEETKQVAMKMQDTPVVTSAAGPEVQAMADENRKLKDILKCSTCHNDFRSQILLKCMHTFCKSCIEARLKSRQRKCPVCSLPFAQSDVQTFYFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGB2</accession>
    <name>M5GGB2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_103677</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632077.1">
        <property type="nucleotide sequence ID" value="XM_040767798.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GGB2"/>
    <dbReference type="GeneID" id="63682860"/>
    <dbReference type="HOGENOM" id="CLU_005874_0_0_1"/>
    <dbReference type="OMA" id="YLGQEKW"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01795">
        <property type="entry name" value="Ubl_USP48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044743">
        <property type="entry name" value="Ubl_USP48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="USP" evidence="7">
        <location>
            <begin position="169"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="8">
        <location>
            <begin position="943"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="1165"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="687"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1101"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1237"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="720"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1105"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1352" mass="150436" checksum="78B96DD39EEA6CB6" modified="2013-05-29" version="1">MPPKGKRKGAPKPRPLSPVLARKRKHPDNEEPTPPSRWSWVKLDGKVAEQITPKHMIWACGFSEESGLPVCPNIWSKDVKEGDEKGKGRAVDTGAYDASVSGKSQKAEVIDLTLPTLCSKKKCRDNPNCLNYLGQDAWEDEDEARAAFLQVARLGYDPRELNRDPEIPVGLRNLGATCYANAFIQVWFQDLAFRAGVYACKPTAPEGKQLEDAPLFQLQATFAALQQCRQNIYNPIKLVESLGLRTSEQQDATEFSKLFMNLLGEQFKLQEAPSVKTLLRDQFEGHLTYCTTCKGCGHTSERDSEFLELELNLGSKSHLEERILEVLQKEELTDDNKYMCSRCNSLKNATRWVKLRDCPPVLHFPLMRFVYDIKTYERKKSKQVIQFPLSLNMKPFLNGGAYMDDQIYDLRGVLLHRGLSAYHGHYIAQAYDVSKGQWFQFNDEEVSPLDGLMGGNSATAAAASSKSSQTSKENKSTNITSIVESEGGIRPKFDEEDERPVPIQDRGKEKVEHVVELLDDEVEPEPSEHPIDSSTPNSIPRYLRSKDAYMLIYARRDVITPADVPECPLPGTSGASAKPDCNTPAIPPVPLAAQREVDRLNEEHDRKCDEYVKREQVVLETFSQVRAVKQEIYSSWNIQTHDDDSVVVNAEQLTKWLGQGLDVPKQPIKETENDIEVLESLAVNAESGVEATTPGSSETPRSSIPPPCGRELENIIPTAPNILPENEPEPIVSDADSSKTLVSSPPVANPAVLQTNWLQGTLTSDSLCEHGLIVPPATSLKRINQAAYMRLLSLGVIFEPALAHTAVCPDCTEHVVSERIYGIRHPELVKVFQDQNIIHSPEDVAYWVSKQWLKDWLSSRPKMHAYGQLDPPPNAEPWKNDLVCEHEGLKISEKDRKLVSAQAYRLLRTIYPGWETFSNTVEVCVVCQEAEDLTSDARADARKAADRERSRLRSMLSINPLASRPVSLIEGFVYAVVPSAFIRAWRSWLIHPLTNSRPTSLDTSIFFCPHEKIYFDSNEAVDMEDVDLVVIKESEWNILAQLYPAGQMIRLEPTTHIDENETVRNVVICNQEVCQQCRRERKSSFEEAPVTMYFMDITDPLPIGNTPNSEQPNAPSASNADDLDIVSVSAQTGKSSPVKSESTLDAYVYGTSGNYDGGLRKSKRLRATKQRGMNRTIIIRKGDTVKDIKVELFDQFNIPTIYQRLFHAGREITDWSDKTVADIGILAQDTISVLEVKPVDEDDDEGGRPKKKRREEGPAFGGTLLSRGGIPPPASATAPAVDTNASHKPDSMDSSHACAVAEALCAAPRPPDSNAPTDLADFEDSLHCPTCTFINPAGVSACTMCDTPFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGG8</accession>
    <name>M5GGG8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_86516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 7"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632357.1">
        <property type="nucleotide sequence ID" value="XM_040776777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGG8"/>
    <dbReference type="STRING" id="1858805.M5GGG8"/>
    <dbReference type="GeneID" id="63691839"/>
    <dbReference type="HOGENOM" id="CLU_013615_12_1_1"/>
    <dbReference type="OMA" id="EQFDASW"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="20"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11465" checksum="2A758B89439B025C" modified="2013-05-29" version="1">MGVTIETLSSGDGVNFPKKGGNVTIHYVGTLLDGSKFDSSRDRGKPFVTQIGVGKVIKGWDEGVPQLSIGQKAVLTATPDYAYGSRGFPPVIPANATLKFEVELLKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGS7</accession>
    <name>M5GGS7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_102965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632902.1">
        <property type="nucleotide sequence ID" value="XM_040767693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGS7"/>
    <dbReference type="GeneID" id="63682755"/>
    <dbReference type="HOGENOM" id="CLU_976658_0_0_1"/>
    <dbReference type="OrthoDB" id="3358989at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="285" mass="32096" checksum="D4EFC7EFCA2E9BEA" modified="2013-05-29" version="1">MLKAPSSDKIPTARSPSKVQFSISPAPTSPIKPSFQCVKSLEHSIHTLLDSPISPISRASPFRQVTYWADLGIISSTCALVGFRSAALWLAWGVPFAHLSLSFEEQTSSERREYHVRRIWMPLVWLALHSLIHLALALADRSLSHQFSFDTMSRDAFLMIVLACAVATRLVYYYQTLQTLPIPVPPPSEKAKRTNKLKEAKAARRINNEEDKRWEHARRRTIQGYESRPSLEPVQNNLRNTSVLPTLPQPPVWKLIMQLLGMDLIGDSWNANGDGQADTHSHPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH22</accession>
    <name>M5GH22_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome b5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_44766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633377.1">
        <property type="nucleotide sequence ID" value="XM_040774606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH22"/>
    <dbReference type="STRING" id="1858805.M5GH22"/>
    <dbReference type="GeneID" id="63689668"/>
    <dbReference type="HOGENOM" id="CLU_070889_1_0_1"/>
    <dbReference type="OMA" id="DGGMRNY"/>
    <dbReference type="OrthoDB" id="10257697at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="75"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="207" mass="23324" checksum="C1FE683C178072E0" modified="2013-05-29" version="1" fragment="single">RAQRRTAKLASNQPLLPEDLDEPEDSVPFALLKVFLVLLLFVALAGRFVTGSVWWGYDGKWVHWRTYWPERMSVFSEMELAKYDGSDPELPIYLGLDGLVFDVSASRRIYGPGGSYSHFAGTDAARAFSTGCFALHRTHDLRGLTAQELAAVEHWKQFFLKSEKYFQVGTVLHEPIPEGTPLLGGCDEHGNALPEEVVERRKRGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNJ6</accession>
    <name>M5FNJ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_40353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624458.1">
        <property type="nucleotide sequence ID" value="XM_040774478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNJ6"/>
    <dbReference type="STRING" id="1858805.M5FNJ6"/>
    <dbReference type="GeneID" id="63689540"/>
    <dbReference type="HOGENOM" id="CLU_038374_0_1_1"/>
    <dbReference type="OMA" id="YLERAHF"/>
    <dbReference type="OrthoDB" id="5946233at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177:SF1">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="28939" checksum="50104799533162A6" modified="2013-05-29" version="1" fragment="single">DQNDKWQCFRLYLHLGMEPFSGSILWLKVWWTNSNPRLIFSYYLERAHFHGGIPLLTQSNPGSENNGIANGHTFLWQQLNLTLIGKLQHRWKCGHSNMKPKIKWSQLCHEFTQGYENLFDAGVHLMMGSNAFHWLAIPWIQRKVDKYVEMHNTSKPHKDKRKLLPQGIPQDIFYHPEWYDNAYSFKVVVTPEDLSLAETKYAPASHPVFELVPEHFHVEMDRLYQALGAPEVTMGNFWTIYQELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNQ6</accession>
    <name>M5FNQ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_71470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624703.1">
        <property type="nucleotide sequence ID" value="XM_040775945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNQ6"/>
    <dbReference type="STRING" id="1858805.M5FNQ6"/>
    <dbReference type="GeneID" id="63691007"/>
    <dbReference type="HOGENOM" id="CLU_063115_1_0_1"/>
    <dbReference type="OMA" id="YWAAWVE"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="275" mass="29846" checksum="EAD6CFFDBBCE9C72" modified="2013-05-29" version="1">MSKPVLYVFLPSVWAKVPELALVALGYPSDAVEKKSINLVEAENLSPSFVAISNPATLPVLTVDGTSYTSTIDVTRYLVEHAPTPHKAGTHQALIDAIHADGIDPNFPFVGARCQAELEAKRAAFPGTFIKTRYAAVTKFNEDADEELKAYYATKLPTLGYLNSIYTDAPQDKVDAFVDTSVKHMQRVNEFILHTLPTCLPESGFVEGSTPGEADFHLAAWIARISLLAGAPTAAEAQGALEKELGEKLPEKVAKYIEAWAGTEAWKEVYADGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQC6</accession>
    <name>M5FQC6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24145</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625973.1">
        <property type="nucleotide sequence ID" value="XM_040773568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQC6"/>
    <dbReference type="STRING" id="1858805.M5FQC6"/>
    <dbReference type="GeneID" id="63688630"/>
    <dbReference type="HOGENOM" id="CLU_031922_0_2_1"/>
    <dbReference type="OMA" id="TGPYFRT"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT99075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="412" mass="44881" checksum="D843CF575E02EB23" modified="2013-05-29" version="1">MAPVAIETPVHTNGTNGASSDSVKKVQQETEHVHDIDPSKLTLHLKSELTPVPAPETLTFGTVHTDHMLVLNYSPELGWSAPSIEPYGPMQVDPMASCIQYATNIFEGMKAYMGADGRPRLFRPDLNMARMKRSADRLALPPFDEQALLKLIKTLVMVEKRWIPTAPGCSLYIRPTMFGTRCGFGVTPSTSATLLVILSPSGPYFPGPVRPISLYAESRVRRAWPGGTGGHKLALNYAPTLRPTHDASLQGYNQILWLFGDDDHLGEVGQMNAFVVLRREDGSLDVITPPLDGTILPGVTRQSVLDLTRAHMLNAPIPGLPAELTLHVQERHMPIAELVEHSEAGRLAEVFGVGTAAVLVPINRIGYGEEGKEIAEETGASGFGPVAKAVREEIMAIQEARRTHVWSVPCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQH1</accession>
    <name>M5FQH1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_118397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626038.1">
        <property type="nucleotide sequence ID" value="XM_040770574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQH1"/>
    <dbReference type="STRING" id="1858805.M5FQH1"/>
    <dbReference type="GeneID" id="63685636"/>
    <dbReference type="HOGENOM" id="CLU_490908_0_0_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
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    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
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        <location>
            <begin position="113"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="113"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="454"/>
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            <begin position="183"/>
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            <begin position="287"/>
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            <begin position="320"/>
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            <begin position="416"/>
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            <begin position="491"/>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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    </evidence>
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            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="555" mass="59757" checksum="C139BFBA3B71C816" modified="2013-05-29" version="1">MARPEEQATEGGTQSAWPATEASAVPLKGNVVPTPVPLPSKSGSTISPTMDETEHSSAEAEEEDEMMLEDTIEGDGEVVENGGDAFARLPETATEEEQYQALTQQSLNADGTPKRPMNAFMIWGRRRRPQLADQHPMLRTGDISKLMSDEWSSMPKEEKEHYQNMAKRLKDAFNIRWPQYVYKRRPNNSRRKRKKVPETGAVDPRMIDTSRGGIQKRGSFSSVGTISNITTFSSRPSTARSMSGQSESPPTTASSRVSAGHIPAISSQSGSRAVPAAYSGYARAEGSAPSSWSWQSSSAVQHDLPVPSSTSAPIPSMRRQSSQHSVSGVSSSGPPQFKHEEEEEVVYRSANSPETEHMWHGSGVSRSFNLSDFQPQQRGEFNMTDFQSRDNMASDPNWISQFQMSSSYGMSGSHNAASESRSYASSQSMPLPGFPGGSRGSFSSLNAIHTFGASTSSSQERFAGGSAGASASPGLETSSRTGYSFSGMNGSFTAASSTSSVTPPADQPRSNYFNGTGFGTAVPQARSNVLSIPQQGHTDERAAGGYWSPHGEQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRF8</accession>
    <name>M5FRF8_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117884</name>
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    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
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        <property type="nucleotide sequence ID" value="XM_040770479.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
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        <property type="entry name" value="DUF3605"/>
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    </dbReference>
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        </location>
    </feature>
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            <begin position="142"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="210" mass="23825" checksum="876612116D1D1A17" modified="2013-05-29" version="1">MVAEEGLPTASEIAAIGPPMFTWEELMDIVDGGDLGLLKRQPALQRRYDEWTKGMKARHGTIENFLIERRLRWNPPLIHPASPSFSPETPATHYRVVPNDWPYSVPTDVVHYVVWSAVPLIGPGDLTDDVERKGMWGFTGGAEHREGEDRQGFGGRSGEGITAFVKREWPEVEWETVWFMNPPKLQTVRGLVHFHVFVRPKKTFANGTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR0</accession>
    <name>M5FRR0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101033</name>
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    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626793.1">
        <property type="nucleotide sequence ID" value="XM_040767512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRR0"/>
    <dbReference type="GeneID" id="63682574"/>
    <dbReference type="HOGENOM" id="CLU_1061824_0_0_1"/>
    <dbReference type="OrthoDB" id="3366022at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
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        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="27764" checksum="D80C1DF0BADA46EE" modified="2013-05-29" version="1">MAPLLVRLSSIALSNAGITETTSQSNATSLPPCPDSPSSGAFSNSCNPTPDDYPAHYSAGQLGVIGFVSCAAVLVAAGGFLWWAYKGRRRAANPTTTSVSVGLPPAIGAQPVPQTVRIPRSAFARRKKRVPALARTPRDNTSEHSHELQPNPAPARNPDGTIRDEWDEEGLETMATWETVDTLVGEKPEGEEGKDETGVGEVPIAIQRLTLGPVAETREVLAEPTPPSPAYHPPGAQRSQYVPVPEVDPKTPTTPSHPSTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRY4</accession>
    <name>M5FRY4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040773727.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5FRY4"/>
    <dbReference type="GeneID" id="63688789"/>
    <dbReference type="HOGENOM" id="CLU_1731413_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="16351" checksum="88800618DBD5DC64" modified="2013-05-29" version="1">MSHRSSHVLRRLTIPAPLGVTAAAPVWPTYGASRSVSGVSYPEPAVIMAHRKTESGEEDDRRELLNARKGYTGPSVILGIANPSPSPPPGPPTPSLYAPSPEPGHPLKQRVEQDAAPMYNYENCILPGKNPNRTGAELYAHYMGEHYRCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSP6</accession>
    <name>M5FSP6_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
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                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
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                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_2426983_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="91" mass="9638" checksum="2F56E34D77ECE87C" modified="2013-05-29" version="1">MDDDSAQMNDPLQPTIPEQLPEPSADDYVIIDNIDPDILLAPQEPSVPDAAVTKAVKTLRAELGQVTKLASEVRLPPPGLSAPLIVGTALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT05</accession>
    <name>M5FT05_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="10411277at2759"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="37228" checksum="93CDAD2E5EDC267F" modified="2013-05-29" version="1">MTDDECLGILEAVSPPSPPPVASAISPETKQTRIPVLNDDILRCIIEFAVSPRSEDAFIYEPGTTQDILALIHVSWRLLEFTRPFLYQRVHLTSKRQVDLLVKRNPPANLPIRDLTIEGSALEHHDLWPLIRDVGGTLERFLIIDNTMGFDILGQCPYTYLEFKTRFPRLWETSNTFKYPYLFDISGVDRPVPVPVPELPHLKRQALLRLGHVHFTDCWTSLEVLATVSNSSLDASLLAVLIESHPRLRELILVLTPERRLMLRSNNVVRAKREFAVKYRGRCVFYDVDSGLTRSSMMETWFAEAIRRGTLWTMKRKNWLSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT47</accession>
    <name>M5FT47_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Galactose mutarotase-like protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_95475</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040777297.1"/>
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    <dbReference type="STRING" id="1858805.M5FT47"/>
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    <dbReference type="HOGENOM" id="CLU_028297_0_0_1"/>
    <dbReference type="OMA" id="ESLCCIS"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="404" mass="44476" checksum="0CEBBECD0A0BC497" modified="2013-05-29" version="1">MAVPAIALEVLPYGLHITKILLNADGRSNDVIIAPFSARELVSDRRMMNSVVGRYTNRLPVGKYEIEKGGVTATVTPIANSRLPHVSLHSGPEGFDRKNWTRVATNKAKNFSSAEKVLLGKLDDESVAIFSLISEDGDAGFPGTLYTEVAFAVLPVPEEKIRKTGDIELGSLAIVYRARLLPGGATITPINLTHHWGFNFSASLDPKTEPDANQHWLRADSSKRLELGPDLMPTGEYSQNELDTEWDWKSGKLIGEKPLPRLDGFLVFDRPRAEQQPVHVPLSQWENGNLLQEALDEKREKAYVPIELYEEASGVRAEFITNQPGVQLYGGEGLQGQGTKKAIHGGKADGSGYTGRPGVFLEFHEPVNALFSEFGKEEGADTILSSGEMYNNYVNVVFCYQPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU45</accession>
    <name>M5FU45_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_116986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628098.1">
        <property type="nucleotide sequence ID" value="XM_040770298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU45"/>
    <dbReference type="STRING" id="1858805.M5FU45"/>
    <dbReference type="GeneID" id="63685360"/>
    <dbReference type="HOGENOM" id="CLU_018012_5_1_1"/>
    <dbReference type="OMA" id="EYLLRNW"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="490" mass="54642" checksum="BE6E3BAEF30F073C" modified="2013-05-29" version="1">MARLLLIGSSLLLAILFVLWYRKVRLSPRSDAPPMVPYIIPWVGSSIAMARDPDKFFANATAKYGSVFGVQAVGFYRYFVTHPTLAKQIHKMSKQFVFTPYRIHLSNKVFGMEKSTLEGTPFFEQEFFDTVHRLLAPNEILKKIVPTYAKYASQEVALYLPSSSPVPARDLLYKMLFRASSFAFFGPTFDADGCVDDFVAFDKALPLRMLNVFWPLTIPGQQAWDGIMKHMRNYVENTGAKGGDYMEYMADHARTHNVDHEIPALALTLLWALEANAPLAAYWAIVLTLFHEDGLKPLYTEVDAERAAWEGANPTLSVVKNPDFFVAQANLPLLSATIQETLRYTASSFSIRRVVEPTTLGGYNFQIGEELVVNGRSSQTDGQYYPNADTFEPTRFLVSSDQAPIGKEKEKLVNSPAFTAHFGGGVSMCEGRHFAQTELKVFIVLMLTHLDISLAPGAKPGDVVLDATRIGLGVIHPKGDVMLVARKRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUL0</accession>
    <name>M5FUL0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626831.1">
        <property type="nucleotide sequence ID" value="XM_040773254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUL0"/>
    <dbReference type="GeneID" id="63688316"/>
    <dbReference type="HOGENOM" id="CLU_533799_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="511" mass="57391" checksum="FA6AA988E2DB8FD3" modified="2013-05-29" version="1" fragment="single">MSRLHSTAASSLAQDITLFNLWCELVGVMTHIKLDYPVQAAVLVDPGGPLPPLLPSAESSVFPLRDIPEDNNATTPSLPGGPRRSSSVLPCPESLPTITVEKLWPLKGTVTKRYSELCQGHLPIQLKEESIPRRGKEYGPYPTALREQTRVLPDSSFSKDDPHYVLSRLPLLERIFGEILETPTSVAAESGMIDESMVRRPWDQLVHLVVMRATSTNKSCTQALHEVAIEACCPYKEDVNPSLVDTSGVDRGSVTSATPDAMLVYKASRPVDDRVDLAAYAKYRAELSFCHHTHVQDLALRIILLAFEWKLRAPEVNARQAVISIATMQRHLEALGITGQISYALAGDVARLWVLGGTQDAHGIIHIFICDVLDMRLAEHYWKHNFFLVNMESWGRTELEKMLAPNLSKDGHGTGEQGVFRLPQKKWRFDEWHSRRIWTHSAIQPLPKKRKRHHEGDRDGESNDDHQRPSAWGRKLRARSMPFRTVRANGNPQHRQAINATDGFSSRSDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV21</accession>
    <name>M5FV21_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV21"/>
    <dbReference type="STRING" id="1858805.M5FV21"/>
    <dbReference type="GeneID" id="63689148"/>
    <dbReference type="HOGENOM" id="CLU_143683_2_0_1"/>
    <dbReference type="OMA" id="NGKPNDH"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12241" checksum="9E521681047DC311" modified="2013-05-29" version="1">MGFLDSFGDNSEQKQAYDQVVGAPHKAPLSHELIAAAASYEAAKAYEDHEAKNGKPQNHQMAKELLAGFAGAFIDHIVESKGLDFVDKEKAKYHAKHHVDQAVEQNWTPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVS1</accession>
    <name>M5FVS1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626582.1">
        <property type="nucleotide sequence ID" value="XM_040773367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVS1"/>
    <dbReference type="GeneID" id="63688429"/>
    <dbReference type="HOGENOM" id="CLU_1126803_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="247" mass="26435" checksum="76AC7A15BC899A9E" modified="2013-05-29" version="1" fragment="single">MTRPLPAVTQVLRALARRAQTSSGILQPHRPVPETQPARTLLPTCERAPIPAVLLALEQLADPSLHSIRSEEFAQTGAISGTWPTSRQEASTTVSLAVQLPGPSFPLPPQQLPEPCLPRTPRTPRPTPREVIYTSPPQVLENALPPLTLDGHSPSPFLGFQDAFPGGFVMQQRPLLLTPTPSNLDFNYNPIFNSNPNPHSNLNTPAVRYTAAAGGSSICLCPPNSHRNGCCPALMLALGIGGLGFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWF5</accession>
    <name>M5FWF5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_95815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626922.1">
        <property type="nucleotide sequence ID" value="XM_040777321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWF5"/>
    <dbReference type="STRING" id="1858805.M5FWF5"/>
    <dbReference type="GeneID" id="63692383"/>
    <dbReference type="HOGENOM" id="CLU_037358_2_0_1"/>
    <dbReference type="OMA" id="CNCGDVH"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF140">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067313" evidence="2">
        <location>
            <begin position="20"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="36528" checksum="7505A57A2C8AE32C" modified="2013-05-29" version="1">MRLPCMSLLLLPFLTLSLAAPNRRATTCNGSPLLCSRQYSNITFIGAHDSFALSPSLAGNQDYDLTQQLTDGIRMLQNQAHSANNTIELCHTSCSLLDGGSLAIYLGKLKVWLDANPGEVVTLLLVNNDDLPVSQFGAVLQSVGLDTVSFNPGKASLTLQEWPTLGQMLDQGTRLVTFMDTNADFQSVPYILDEFSNMWETAFDVTTTFDCVVNRTHGDPTTQLSTINHFLDIGTTIAGIGITMPDKPALPQTNAVSGPNSLGAQAQECVAENGRAPNFLLVDYYEVGGGSVFEVAAELNGIPYSQGVIASVPGTAGGTGTGGTGTGGTATTLAGGRETSLGGFLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWJ8</accession>
    <name>M5FWJ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1771-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627651.1">
        <property type="nucleotide sequence ID" value="XM_040767489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWJ8"/>
    <dbReference type="GeneID" id="63682551"/>
    <dbReference type="HOGENOM" id="CLU_1042144_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067285" description="DUF1771-domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="28512" checksum="EA9B7BB6E933D536" modified="2013-05-29" version="1">MMLIKTALLSFLFAALLSLAAPVPSLDVGGYQLDAGESAALQRRAPNPGPLQHQQLTGTHTGGHPSKLNLSAGGAPASPPSAKKSIKGAAIAIGHFARRMFGKKSQTEPPVQPLPPVQPLPLAPALPSHVTCGIPHDNIFHNVLAQLAQTHTSEGNHLLASEIYHRKAVIHATMAGQYRNAIFDRKMRYMGKKMPSEESQVVETYKRSEDTLLSLKTVAENNHAESLKAHEKGGYKTHRMSEKTRQLQEAADHAVMEWGNHDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXI4</accession>
    <name>M5FXI4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628081.1">
        <property type="nucleotide sequence ID" value="XM_040768668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXI4"/>
    <dbReference type="STRING" id="1858805.M5FXI4"/>
    <dbReference type="GeneID" id="63683730"/>
    <dbReference type="HOGENOM" id="CLU_2049626_0_0_1"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="33"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="120" mass="13309" checksum="3F3760F8A3DDD715" modified="2013-05-29" version="1">MAWLNKKDLPPLPSTHDNLRVLAIGTLYEIQTFYLDAFPDEGHKLRAQSVTRERGGSAANILSLLAQFDGVSPYLCAPVGSRRESTRIESELGDLGIGTEFLVRREGEQVPTSYVMQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXT1</accession>
    <name>M5FXT1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_118635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625234.1">
        <property type="nucleotide sequence ID" value="XM_040770626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXT1"/>
    <dbReference type="STRING" id="1858805.M5FXT1"/>
    <dbReference type="GeneID" id="63685688"/>
    <dbReference type="HOGENOM" id="CLU_1120792_0_0_1"/>
    <dbReference type="OMA" id="MMQDHLD"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="28436" checksum="7745D01ED370A783" modified="2013-05-29" version="1">MDEPLEVGATFPAPPNLYKRYTVPNLSLLKKLHVHGPSALEDEPDVPEWLSELDPPRVDWVVEEGGYHSFGEFWPIPSREPTLAEVGLVQLYDPQARDLRPALHSLLRTLLHSYHTLLSTLLSGPQTHLGNLEAQAQAQAQALDSPVFMYTEWMRAAGVNMMHAVNRLRGMQARVGLEGVMRARVEERRRKVREIRGKCKSIEEELQKLRDRARRLTAARDQLVLHTAEAEEEPSKEPATIAHVAEWVAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY99</accession>
    <name>M5FY99_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625429.1">
        <property type="nucleotide sequence ID" value="XM_040773729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY99"/>
    <dbReference type="STRING" id="1858805.M5FY99"/>
    <dbReference type="GeneID" id="63688791"/>
    <dbReference type="HOGENOM" id="CLU_631652_0_0_1"/>
    <dbReference type="OrthoDB" id="3243310at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="434" mass="48305" checksum="098F5C0A917B84C9" modified="2013-05-29" version="1">MGQMALPSQHWALEDAPTREGSVGTSFEGNMDALMHYIGRPSAPIPPTPFTQTGTPAIDLHAHLRDHEEEIPPLPDYAYPPLHFPHEPGAMTESTMSSPFDGNPFLPYQAMSLQSTPSVRGLNLLRSDQNWMRSRLNSRPGQTHPGYNHIRPPSSVSGESAEPQDTESEGEEDEDDVWIDEASDDDLDAEFHQDYIVDKASRRTRFESKMRTLVRQFRELDRTTDATMLLIASNPDQRHTHLVLSRSVRRHPNYIAFAQSARHSFAQVADSRRAERASRARMTQYQQRPSTMRRKSSGFMLSSYPAGQDNSGSATSDSATSVTRSAVASSMTSLPVLEPLKTLRAIDPSKMSAVDFRTAMLAELDKLGAVNGGFKQHAQAQPDSTEEMQRRALQQYQHVGLTGREGAEILWRNMQVDRSLSSTDATGVNGSDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYC2</accession>
    <name>M5FYC2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627727.1">
        <property type="nucleotide sequence ID" value="XM_040773122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYC2"/>
    <dbReference type="GeneID" id="63688184"/>
    <dbReference type="HOGENOM" id="CLU_2867608_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="7566" checksum="52CA3BCC9C6D573C" modified="2013-05-29" version="1">MKIPLIGIRQMLLNVVRVPLCTYPKFMSHHHLLRRFRRFISSTQLANFSHRVGLQVDKSFLFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYE7</accession>
    <name>M5FYE7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase/thiol ester dehydrase-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_25633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795884">
        <property type="protein sequence ID" value="EJT96547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623445.1">
        <property type="nucleotide sequence ID" value="XM_040774247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYE7"/>
    <dbReference type="STRING" id="1858805.M5FYE7"/>
    <dbReference type="GeneID" id="63689309"/>
    <dbReference type="HOGENOM" id="CLU_052827_0_0_1"/>
    <dbReference type="OMA" id="RVFYNDK"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="192"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="35933" checksum="3AE1CD678E0BEC28" modified="2013-05-29" version="1">MFPIRGGVRYLSSPVRTCLNRQTRLMANVGGAGKQFQAEVERRLEADRTTRRRARAGFWTFAAGAFICLGAYGLGSAFPPSVIRLISPRPAAAPPPPDSPEALAQVQRLEKQLMSLPQVLELSKKTDGPDAEYYEARPYATYPRERAVNSLTAGALRGAGRLAIPPLVFAKRDESEAKVFIHVGRGVCGHDGIVHGGLTATLLDEALARQAFLNLPSHLGVTATLTVNYRAPVMADQFILIETKLDTVKGRKATVSGCIYDLDGKLLAESSALYIEPKYAQVLANGDVKHLLGVHTKPSVGMEEKPHHRAGTGEPMPMAGEQVIHGEPPKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYK4</accession>
    <name>M5FYK4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625524.1">
        <property type="nucleotide sequence ID" value="XM_040769070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYK4"/>
    <dbReference type="GeneID" id="63684132"/>
    <dbReference type="HOGENOM" id="CLU_537494_0_0_1"/>
    <dbReference type="OrthoDB" id="5321006at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57027" checksum="6CFCC827D38490EE" modified="2013-05-29" version="1">MPQNIQAMQNMQNMQGRQPAMGGMNPGMMQNMQNMQNMQMQGMQNMQGMQGMPMQGMGMGNPMTPVRGPQQQGAAMQPDPQNHYLRANQTLPLAQPLTYELAVQYLLKSVSIAQQTPFYWIPIDKPSDNDLYLVYHTNNVHWANDGVRFLENESSFRAQIAGHELEVKETKYGFIPGAETQANRVRRKFRLLKGGSPHLWLIHYTRGQAQPVPPIFQSTPSRKYPIPPAPSGPVLVFSQPPRPGQPLPPGGATQVPGRSPQKDMQRAMMLAQQQQQQHQQQQQQQQQQQHVQQQQQQQRAQHPHGAQHVKVEDDSDDEPEFLTKRDLAKARYMRNHEFMQDVFAFPGKLPDPAADPWSTTTPLSLEQKLEKLKAEIVSASATNATRVQALKAARRDPEMEVEAEMEMEREGVRGEGEEADVLPEVVVEPVKETQVQEVATDMEVVPEVGEEKAEIAAAVNEEKVVQEEELEDVEIEDAEGEDETEDAAVEAQGQENEQEKTEEATGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZM2</accession>
    <name>M5FZM2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630370.1">
        <property type="nucleotide sequence ID" value="XM_040772210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZM2"/>
    <dbReference type="STRING" id="1858805.M5FZM2"/>
    <dbReference type="GeneID" id="63687272"/>
    <dbReference type="HOGENOM" id="CLU_003080_0_0_1"/>
    <dbReference type="OMA" id="SEAHWAQ"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033511">
        <property type="entry name" value="Cdc24/Scd1_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="325"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1120" mass="122118" checksum="6086674B4DA9C825" modified="2013-05-29" version="1">MAPIPQAVVAAPIENEDDCPVCLEPLSFSFRIPGEKPHIVPECGHALHEACFSAVYGPLSSRTGAGRKTNLGVCGVCRRPMKVGDGDSSKNNKLAALTGMGGKRLQNTTQLYPGLENAGVARPGEMAYMSPRPGARTPVIIDSQSPTDDDALEPIRSPPASTHSSLSGQQSVYVTTPGIQVRPEFPTIPRNGQPTQAMTCIVIVELPNRKPPDMRSPIGRGRMDSSWGADQRIMRGREFEDREPVTASSPSYHSGPLRPWEREERQTGGSIDVGPVSPISPKEVLEPTPQSPNIPLPPVIETPNPAFQRIADDLKARIADWKGHELAQMGALQMFDILKVRRDSQIREFYVYLFREAVICVIEEKKKGLNRILGATSSSGGVEGGGKGSLRLKGRIYIKHIRTVTESDEKDPEQSLTVHMEDESFILIYPDRTSMQNWARHVMALVEDSRRRDGLPPSSEKNSDPECESGPPVAMFNSGKAAKLLGGGPVPSGRDGRDGASLAPSGSGGTTMSDSAASATEDSLLQSSQRSTMSSVVTGASPAQYVRGPNGQMRLQKAPSASSLQHSPSYNSLGSPMSPGGAQNVPTGQPSNLLPPLPHPGLDLVVIVSVPTPHAWQLATGSASLKLNVLRSTLDFILGNMGPRDRLSFVTFEVGLQGRIRRTPFLSPGKSTSKRRLEAFIAGMAKDGNDEFLVPPTKEEKTDVVTAVNNALDVVLQRKNRNYVSGVILVSDSADTMRRAQMDLVLARTEAANVPIHSFGWGRSHDPACLWLMSNHTQGTYTYVKDWYDLRECLAGLLGGYFSMGLLNMKLHLKVVDGTRFRIRKVSGGPGAIVSSSGRDVDIDIGELRYGERKEMLVELELDNQSDPAATRRGLSALSEADELRSRGPLNATDQFVAQMGLDALSLNEPTNLVDGVMDRMIDEAPVFEVDGSFFDPVSAKNVSRLVHPVLLTVTLMPYSGRPQTPHGQSDPHIVRRRMELLASEMMTRALVLVSRKSFEQAGRILAETQRILRTVLHTVTQSLPPPTSGGMGRSRRELLILGTVRSLQSVLQDIQVLTDALEDTRDEFAFDQRNFGAQQAMILRDQKSWTSRTATEKLFFNSELSPELVQRSADWIVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZU3</accession>
    <name>M5FZU3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_89047</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628931.1">
        <property type="nucleotide sequence ID" value="XM_040776892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZU3"/>
    <dbReference type="STRING" id="1858805.M5FZU3"/>
    <dbReference type="GeneID" id="63691954"/>
    <dbReference type="HOGENOM" id="CLU_010119_1_1_1"/>
    <dbReference type="OMA" id="MSLELCA"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF885">
        <property type="entry name" value="2OG-FE(II) OXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="193"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="375" mass="42001" checksum="BF4FD9E34EADF4E3" modified="2013-05-29" version="1">MPVAVEQPFSEIPTLDWSLISSQSPADLERFLADLRHALVNVGFMYLSHSPVPQPLVDELIDYIPQLFALPLEEKKKISMLNSPHFLGYSVQGAEFTKGARDNREQFDFATAYVCPWKEGDPDWQRLWGAPQYPPDSVLPGFRKTVLSYLSHLQKLSMDFIRLMELALLIPPGQLTQFYDTDEHMQHRSKVVKYPSAEFLRSEDGDQGVGPHYDAGFFTFVRLLQASPQPGLQVQNRAGQWIPAPPVPGTFVVNIGKALETVTQKVAIATTHRVVSPAKGEGARYSVPFFQSIALSARVGGAKIQIPKEILDLKRARGDEVVTDSVNFSEYEREVSGHVQLIGRIKSHPDVGQKWYPHMYAEIFPHGAPAFGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G062</accession>
    <name>M5G062_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_107081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629041.1">
        <property type="nucleotide sequence ID" value="XM_040768403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G062"/>
    <dbReference type="GeneID" id="63683465"/>
    <dbReference type="HOGENOM" id="CLU_2250036_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067415" evidence="2">
        <location>
            <begin position="22"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="104" mass="12057" checksum="639D72E318C2B522" modified="2013-05-29" version="1">MFTIRITPFVSLLALSWLATTTRVLQTENQWLATVEARSFDQLDVGYGVRHLDNRDIDLHDQDELHERETDEDSSWLELRTPPDPAEPEKAAEQLVKEHEKTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0D4</accession>
    <name>M5G0D4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629086.1">
        <property type="nucleotide sequence ID" value="XM_040772608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0D4"/>
    <dbReference type="GeneID" id="63687670"/>
    <dbReference type="HOGENOM" id="CLU_053011_0_0_1"/>
    <dbReference type="OMA" id="RPRFMAQ"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="38454" checksum="06402FAB7E6ED23C" modified="2013-05-29" version="1">MSTVDEKLTNLALEKEYKFLTKEQVQHFMQKGYLKLPHAFTKDRASEWISDLWVRLGMDPENKSTWTQERIHMPHFRRELVSDFCPQAWGAMCELLGGQERVSEGSAVWNDGFIVNLGRPEDEGKLTGPRDLPDWHADGDFFLHFLDSPEQALLVIPLFSDIRPSGGATFIAPEGVGHVARKLADHPEGLQPGLGDKPDQFDFLALMRQCDEFVEATGEVGDVYLLHPLILHCASRNSLRDVRVITNPPVSLNQPFNFNRANPSEFSIVELKTLQSLGVERLDFKPTTERQRIVPERVKRQQRMKEQEMERMKNAGQEVPKAKWTQPATGMEHAQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0F4</accession>
    <name>M5G0F4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624180.1">
        <property type="nucleotide sequence ID" value="XM_040775554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0F4"/>
    <dbReference type="STRING" id="1858805.M5G0F4"/>
    <dbReference type="GeneID" id="63690616"/>
    <dbReference type="HOGENOM" id="CLU_600130_0_0_1"/>
    <dbReference type="OMA" id="RTANICK"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF20">
        <property type="entry name" value="PRO1A C6 ZINK-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="400" mass="44715" checksum="3B1567A0F55A3142" modified="2013-05-29" version="1">MAVPSDLNPVLAINLPLVFEHPPGQNSATEALRLSLLGVGAIHQAYLLSRHGVNSASQQEMMNLAVTLRLTATHYLRMACLSPQGMESDAALGASITISLIDIFTGGQNWTANLALAKTLVDLRGGPRTIIATNKPHLIDGGAKVSPARLLLEILAVYDTFGSLTTGEPPTILAPGSEDWWFDGDKTSYHLFSVEKVFGMSRAMIELVARVSTLAARANKHRRKILELQMEDDRSPLEQEEFERQAIESEAMALYEEAKTWTSSALKHRLHPRVEYGNTAHRQAMQVILLRDVLRVDRLDPRVQEAVQSILKICTESAKRLGMGVDLTWPMIVAGCQVEHLDRDKVTKTFEYFREQCCFDIDTAEQIVREVWRRLDANPNDPRADWRSITEDLDLKVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0S9</accession>
    <name>M5G0S9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I restriction enzyme R protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628622.1">
        <property type="nucleotide sequence ID" value="XM_040772702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0S9"/>
    <dbReference type="GeneID" id="63687764"/>
    <dbReference type="HOGENOM" id="CLU_078038_1_0_1"/>
    <dbReference type="OMA" id="LQCYEAF"/>
    <dbReference type="OrthoDB" id="3253976at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21993" checksum="C45936621E6A2EF6" modified="2013-05-29" version="1">MTTVFETLGYDTYPKGAAVMRQWTIKLNISGTMKTVTPDIVLIRAQDRIICLVCEDKREDQPKDPQAQVIAEAIAAFQCNNEQRLESGLKKLKQWTVPCITIKGTEPALYMVPVTKELNVAVMQGQYPNHVTRVKSCIMPWNEPKSRLGRTDMTHVAFRREALRMLVCFKNLVRMQAKIINEKAAKNNIDDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0W5</accession>
    <name>M5G0W5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_79392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628677.1">
        <property type="nucleotide sequence ID" value="XM_040776395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0W5"/>
    <dbReference type="STRING" id="1858805.M5G0W5"/>
    <dbReference type="GeneID" id="63691457"/>
    <dbReference type="HOGENOM" id="CLU_022144_0_0_1"/>
    <dbReference type="OMA" id="WEESPEA"/>
    <dbReference type="OrthoDB" id="3365519at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="291" mass="32732" checksum="5B37C484BA2EB4DF" modified="2013-05-29" version="1">MGVSIATYQYASAADTYLQSQSHDPAALALCRSFTGATRSYTRVVLRLRAQAEAGWDSDAFRSPLYRSGHAPLLRVFVPSPQGGWLGDESVVECEKELRRAGVMKLVRRGDVVWDAAVSDEGNIGRLIWDGNYLLDLEYNYSPSGQLPHYFNSLAYPPSYWHKVIRTNTNPLAFIDLRPYGREIMQNVQLVQDRVQSETPQGGYHTIVGYSHRSVARLLRGTPIPESKEVVDAGWDGRIIVETEGTNEGLADLQLRCSSRGTKSVYRILREKSRPGEVWIRCVRAKEKILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G9</accession>
    <name>M5G2G9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626954.1">
        <property type="nucleotide sequence ID" value="XM_040773292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2G9"/>
    <dbReference type="GeneID" id="63688354"/>
    <dbReference type="HOGENOM" id="CLU_1059839_0_0_1"/>
    <dbReference type="OrthoDB" id="10637894at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="28234" checksum="B1409ACF1D591372" modified="2013-05-29" version="1" fragment="single">MPMQSPRSSMARPRTAPNPARPNLNASDEDGRRPSAPAIVQTQPEGNVKNVLEHILPPEELARLMQPSPSPRELDSIPPRRPGNTNSVTSRRGSNAGSLRSTLSADKSYFFASPLPSPAEREFSPWAMPYDNPHESGLPSLPPPRRRARNPPAGVNLYPLNTSSRPSSSSSGSRLSVPTSSSAVSPISSTPTSASAVRPNVSPRLSNTRNFFPQRRPPDYAIPPLPDPGIKAAIVAAAAKEGEKPKSDEVQTLHASEKKKKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2H1</accession>
    <name>M5G2H1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624860.1">
        <property type="nucleotide sequence ID" value="XM_040773891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2H1"/>
    <dbReference type="GeneID" id="63688953"/>
    <dbReference type="HOGENOM" id="CLU_2867610_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="7087" checksum="EAB0EC5C5C163B2A" modified="2013-05-29" version="1">MRNIANPHLNGHDIVPTHWAKLVDLLVVMSQPHVAVARHCDVSEILDGDRENGVPTCGLLRLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2H8</accession>
    <name>M5G2H8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629788.1">
        <property type="nucleotide sequence ID" value="XM_040772565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2H8"/>
    <dbReference type="STRING" id="1858805.M5G2H8"/>
    <dbReference type="GeneID" id="63687627"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_1"/>
    <dbReference type="OMA" id="TRLSMFW"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="404" mass="44838" checksum="3C7E72CBA22B219B" modified="2013-05-29" version="1">MSKSVIIIGCGIAGPVLAMLLKHKGFEPHIFERLPEIQVAGISLGVSPQTLKVLNILGLAEKLIALGESLDHFRTYSQLRGEQLGTSDIPARVRDWLGWPMLMIARVRYCQFLYDSAKERGISITFSRNLVGVKQEGERVRAIFEDGSEAEGDLLVGCDGLHSAVRNALFGKDEIKYSRLAQIGGISITPEILKSPVHMAHQYLGDGVHFVATPIGHEQMAWVATFPEPNEAREDWKRISIENAKELLDGLPVANWDNGPKDVLAHATFVTKYGLYERPICPSWHKGRIVLLGDAAHPTSPFLGQGGNQAMEDCYHFVRLLCKAAPFTDESLESAFKEYENIRIPIVTKSVARAKVEGQKRVLSGKEACLQRDEIMLKGNGMDPQRVQWQNDLIQGPFMGESEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2J6</accession>
    <name>M5G2J6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626974.1">
        <property type="nucleotide sequence ID" value="XM_040770429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2J6"/>
    <dbReference type="STRING" id="1858805.M5G2J6"/>
    <dbReference type="GeneID" id="63685491"/>
    <dbReference type="HOGENOM" id="CLU_533179_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="253"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="511" mass="58042" checksum="912AD392A93BE705" modified="2013-05-29" version="1">MSSQQPPIQSRGWRPRLVSLTSRGKEPDVPHQASRATSVRGKQSSLDEGYLTDVESSALRKSSSPQRSPSQQKSNGAAERPPVPPLPPAVKSNQQPASFMFRPRRATPDADGGYNTDGTAARSHRRTRTTENPRASTPNPSGGRADSRAALPPLPLLPIPKRKTVHPPCLSDSETERLGNAPASRLSGSRNDREMQLLTCIPYPLNPFDEEARRVEKYMYCAAYYTKPPYVKRHYRGPSFLEYRRNKGPRNALDIGSGYGYWLRDAAASWPDTRFVGFDAFDLPLVEMTVEQLKRISFRQGNLLDSVLPFHRGEFDYVRLANMRLAIPDKAWPSVLMKLCNLISENGILEILDDGWTFLGTRYNANMATFKMSYEEHVQFMLNERGFQQAIEAPRHFQRLVEAPLSNIEHMHPLIRNMISIVNTDPKLDWRWRKTLFLAEEAVRDTLLPIVARTQPDSSSSAPRMTAQEKHDLFSQDVDDLVGLLKVTPSVHRYQPSSFHYLVYQRRTRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2U3</accession>
    <name>M5G2U3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629439.1">
        <property type="nucleotide sequence ID" value="XM_040768305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2U3"/>
    <dbReference type="STRING" id="1858805.M5G2U3"/>
    <dbReference type="GeneID" id="63683367"/>
    <dbReference type="HOGENOM" id="CLU_383097_0_0_1"/>
    <dbReference type="OMA" id="RFAGSTH"/>
    <dbReference type="OrthoDB" id="2587928at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="78038" checksum="58DF27F92E2B8099" modified="2013-05-29" version="1">MHRFRAPWSKDKQSSTPPPPPSNKPPPPPIPSHSRPPPPPPPRPQPPLPTTTISPPTAHPPGAIYPPGKWPTPELSIYPLNTWLILSSPDKGWTSASIQAALDALGEGGTLYLPRSSKWDISEPILLRPWQELATEGYPTEEKDMAALEATPGCRPHLVNCWNVSGVRLRNLLIDGKHDVFGRDDKCGVMVQFGGPDPACHDQWCDRCIIRNPRQWSCFQAFEGTTNVRITNCRIGPAGIGKDIIEGHWADGISFAASHGLVAGNEITDATDGAIVVFQATGTLVTSNTIVCYSRLLLGGINMVDHAPGKGDYSHTRVVHNTILTAGGYIVTAIAQGPTAWGAGPGEPSEDKLNRNAIVARNLIHYQDRGRGKGAIGYGFAVSADVRGWTCVENVSDPGVVYSGDMSDGDWGLGGMSLAPGPFVRSAGPVEKLGVLQEEFVPGLLRGLLAVKPGRSPVLRLFPRQLSLRPGEKVQLKHWALEFRLDGDVQVRNEGGEIAWSAGLGGTIKGHEKTAVLELSANGHLWILPFPASPTPLLTLTPLLPDTGLPGCTPQAESLPSLQLSDTTPHLQLLTPSGGILLSSCYEVPWNTQFPVDTPVCQPSVNAESTLVAVLSPLGQYMILSSRRGRVVELPIKWPLEMGRWYILWQTRNAPLPQFTEGTLAFQGDGNLVLYAGGKALWNTATYGPPEKQARWMKWGDGGAGRPYLELVNEARERVWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G303</accession>
    <name>M5G303_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627109.1">
        <property type="nucleotide sequence ID" value="XM_040773146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G303"/>
    <dbReference type="GeneID" id="63688208"/>
    <dbReference type="HOGENOM" id="CLU_2722180_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="80" mass="8814" checksum="30248816251F3CFC" modified="2013-05-29" version="1">MAALSQNEQAEVHRRVTLSDRIKTHLSSIQANWLRPGAQRQSFWGADGFQATKGPLGLAAYDWTITGNGLRAVISPKTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3M1</accession>
    <name>M5G3M1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_109174</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627354.1">
        <property type="nucleotide sequence ID" value="XM_040768830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3M1"/>
    <dbReference type="STRING" id="1858805.M5G3M1"/>
    <dbReference type="GeneID" id="63683892"/>
    <dbReference type="HOGENOM" id="CLU_000288_81_13_1"/>
    <dbReference type="OMA" id="FLHISEF"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
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            <end position="1874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="2022" mass="216421" checksum="A11DBD5CF4DD1EE6" modified="2013-05-29" version="1">MANPSPSPSPLRSPSPLPEGLTEISSPSFPSFPSSPHTHSQDSLPSLDVNTLYSWLGLSPASAHRRGKENSPHSPSISLPRSMRAVRAREGRALAQMAPDSPSHPESSSASKIPRSTRKPTNPPRTGPNPPPSSYSYTLRTPQKSSTPRSSRFRPRPRHKQPHHEQPLCPETSFISTSQGSTLSRSGRRSSAEISAWAASGVFPQPEGSTTPSDGAGGGGGQGSGEPALGLEGGGGWEKAVTREILELSFSRMDRSSLAVSVRSKARPKEPESRASASAGRSSPKWTALDRRGTYWHKRGHGESDSGQAEAEAEAEGEGEGEGRPRLAPDTPSRPRWADFLFPSPAPAPPPPPLTPLALTLTPLTPLIPHHAPPAEHPPSDPGSDGVSPTPAPPVHRGITPAGQLTLHPPKAKARAVSGPAVFGGRPTVRLVLAPSRPGHGHGHGHGRGSSDSRYEEGNGAVGVDGEGKGKGKGKGKGRSASAPLSAPLAPAQPWTEGRAGRPEGQSRKSWSSRTRSTSTPSLWETSILEEGEWDTQLEGRGRGRGKRERNGLQGRELGFCEMGSLAFPRLTEEQQELDQELELEYEHEHERGWERLPRRVSLKDVILPRPVVVLLEPATSASASAGRAPATATATVTGTDGKRRSGSGSLFSLKPEKLDRMSLGGERVRSRRLMKNSAGAGRSGSSKIKNRSKRERAKGWVLGARGPEFEKIDHSRVCTSSSAAAAAAVGECVSPEVSQGPESERKELENPGRSGETVPVTALDGQDELEDSEGRIRKWLFFIGFVFFPACPCNVRKRMRSSFDFRTPSPAPVPPSPLPSDHPLSLELQSLRTALTQYQTAAHNSAIHLQHLSLSASSAKERNKQLTALTLRLQEELALLREKPAETNVHDREFTLVVRRLSARVEEVERALEARVRRALELEDKLSVLGLEERERRVKEERRALERLARDVVDRAGRAASLPTPVSAGGDITGPSSSHSLSSSPGQYTHSDLRCSLLKLLSESSSHTSSLERRLSDALSQLEAKEQELAETKEELDRGRERAAQAEGKWEAAKADDRAAAGLVERYMRFSQSTTDSLRSTISTLQSRHSSTVQTLQLQLSQSQTSLARSERQVLALRSALDDVTQDVVVHSEGRRREVGLRLKLVGREERWVGAVRRAVGRAGRELAQGKGKGKGKGKERAEGGEGEVLQRLLLALREVLDEVDGPCSSPSPSNADANPTQPEGKPYKRAAQAVHMGTGALGRIVAAEQAVSGLVLELERETGRRMGLERERGFGLWEEGRGGEEVDGQLLGQLQQGQGQQGQEEEREHAHEREEQEVPEPEADEADEADEQTRLLQEPSTPLSVPPATEAVVEDAGYAPEGHQSEREMNGHALAAGDAELPERTEKDGRVGPVCGSGSEREYKWGVRDVGNGHPEAAVGLEDSRPVDTPGRESSALPNGDMNGQPKVDTEPEVSKSVNASGAKVNGYLEHVAVPQKDRKSAVLPDGGMNGPPDAAVGSEESSESIHVVGGKLNGHAEAASGQEETTDLSAVSVNLNGSAEPFKVADAESKPFIEEPGSEQVPQSTPAAATAAIAISPDAQADINPQVAELSDSSSVETLALSEWAPSTRSLPTLSNESLISETPTAVSSGALNEFVSEKVASAVPEEIVDVPAPVMIVADQKAAIEAPQEPVQIPEPPAIRFEEPAPAKPIEEAAKSPEEAHSDELLRQLSEASARYESIQQAFKGCHNTLLALRNELLSPASPGPVAEQAHLLSTAVNRLDDITEDTRVSLEIRAIDDARLAKGFETLLMMNTHSAPGTQLYEQIEAFLAGEDATGSNVQHTFEQKLDDLEHDISIIKRAVHEWMTGDTLTAGLSDEPPHAPDPTRPAPSPWGWTSAFLPSRPNSPSPTFGAVMSGAVSGKPRSPSNNSTGIRFPMLAPLSPREHPLAYLRLRHSMPSPSLTSPAPISPSFAAYTVLSPPGSASSVVLGLPYERRRTTSAYMAGLAPGLGMRAPPPGRRLPARAASTPQLVLSSDDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G486</accession>
    <name>M5G486_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ras-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_53924</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627539.1">
        <property type="nucleotide sequence ID" value="XM_040775214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G486"/>
    <dbReference type="STRING" id="1858805.M5G486"/>
    <dbReference type="GeneID" id="63690276"/>
    <dbReference type="HOGENOM" id="CLU_041217_21_1_1"/>
    <dbReference type="OMA" id="NDNVMRR"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000573">
        <property type="entry name" value="RHO family GTPase Rho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="23712" checksum="9DE8BB8038B88FCB" modified="2013-05-29" version="1" fragment="single">IRRKLVIVGDGACGKTSLLCVFAMGEFPKEYEPTIFENYVAEIRLDGKPVQLALWDTAGQEEYERLRPLSYSKSHVILIAFAIDTPDSLENVSVKWIEEVRSICGPQVPVILVGCKADLRPPDAPVHPASGVNYPYILRVRGEQMASDIGARAYKECSSLKNEGVDDVFEAATRAAMLMREGAGGAGGTGGRRRSGEIPSLGRRLEREERSGCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4N4</accession>
    <name>M5G4N4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_100818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627719.1">
        <property type="nucleotide sequence ID" value="XM_040767493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4N4"/>
    <dbReference type="GeneID" id="63682555"/>
    <dbReference type="HOGENOM" id="CLU_863363_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="36208" checksum="95136036794D525E" modified="2013-05-29" version="1">MLNLWIFYRDENRVIGLSINEEMTVVKLVTECMNHLQINPTKAYIKLYQLDHVAYEADVDFDPKWIQGKRSVPLYKPLTDYIVSPNTPPWLSFCVVKGGLFQVQCLDPAHISICAVDRKSAAFFDHSGVESGEHDALKWNLPLSKTFQNAVLLGKNADAPSKAAMPREWIEAQRRGPNLTGRPPEYLGHPIGIYAPVFEDFKYSFSNKNLDTITPEEYSLAHLLIHLANAVYNDEDTRRRNIEPVLNNMLGKVALQIVNDDKSAADGSIMADVPNSQTLLAVEVAIYEYKPEITVGYSEANNEIAATARKSWVQDRVNVPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4N5</accession>
    <name>M5G4N5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625590.1">
        <property type="nucleotide sequence ID" value="XM_040773623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4N5"/>
    <dbReference type="GeneID" id="63688685"/>
    <dbReference type="HOGENOM" id="CLU_1059840_0_0_1"/>
    <dbReference type="OrthoDB" id="3219854at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067471" evidence="2">
        <location>
            <begin position="21"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="29861" checksum="0BD3400985D9FCCC" modified="2013-05-29" version="1" fragment="single">MMLLHISVFLFFAGVIVFLGETDNGGPVFKAISTLFAATLTIYAVISSLPLIFPDCPYRFPPMKVFRVWILQKMHKRWRGKATFREQELGVIEQDTAVVEASALAWLLKVSETSEEKDDVEDAALAAMDQLTQSNEQRNAMLREGILHTLYRLFMDCEEDEENRMVRILPAIEALWKSDETTPGTQYTAKERVPSDDLHIAFYNKLVEVLETSQSQRLLGAAIQLPKQFSGYPVAEWPIASRLSIPKMIDQLENDRFNTEGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G541</accession>
    <name>M5G541_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cwf19-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_78259</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF19 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630239.1">
        <property type="nucleotide sequence ID" value="XM_040776326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G541"/>
    <dbReference type="STRING" id="1858805.M5G541"/>
    <dbReference type="GeneID" id="63691388"/>
    <dbReference type="HOGENOM" id="CLU_015540_2_0_1"/>
    <dbReference type="OMA" id="MVEFASH"/>
    <dbReference type="OrthoDB" id="1109245at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF5">
        <property type="entry name" value="CWF19-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="4">
        <location>
            <begin position="557"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="3">
        <location>
            <begin position="688"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="90881" checksum="DF6F97CF754F3CB7" modified="2013-05-29" version="1">MPSEKRSSQNCDNDERAHKKHKHRKDKGKDTDRNEKKRDKRERAALEVVDDDDEGVWVEKNIDEDGAISLVADIPSAADMRLKSHASSPPPVPLPPSTATSSSQREEWMLPPPSYQSTKPIVPSPLSAHPVQAELETDDNGQMTEGYGDEATSGRTLEGGVDFFSSLGTERKKKPTAPEPVSHKCTCSRAKADCMHQPKYSQRELNPDINPSAAPLSKERSSKIVPGGPGSSWRMAKLRHTYEEAEDSGRDIDEVALERYGSVEAWQEAKEERKILDERNDRTRNRGDRDVDRRRGGRDDRDDNDRRERYGRTDISSGSSRPASRSSFRGPNESNPSTPGVRTAQSSSFNTPASRASPRPTFIPRTSLPAALTPPVRVQAISASGSGAVPTTESLNKLQAKVLRAKLMNAPSAEALQQEYDAAVRRHEEANTAGETRTEALPVFDVQGRLYDIGSESVLPPGNERKRKPLDIYDREGNVLRVNDDDDTLSLGDMLRQEKAAAKSADGADMDAELARKIATDAKFEDDLDYIDDNAEKLARKRMRTEAMKRAFAIDDYARTKKALDTCPFCFGEDDSAPKAGVVAMGTRAYLAVPAFEELVDGHCYIVPVQHHLSMLEAEEEVWDEVKNFMKTLMQMYNDQGKAPLFWETVISLKPQKHTYIEVIPLPISSWQDAPAYFREAILASESDWTQHNPLIDFSKRPGGFRRMMVETLPYFMVQWDYKSEKGYGHVIEGDSGGVADEDNDYAGEEEGRKGTFPRNFAAEIIGNMLELEPRKWMHPRRVDYSMNSQRAKSFGKMYAKYDWTPQLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G560</accession>
    <name>M5G560_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Protein phosphatase PP2A regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630698.1">
        <property type="nucleotide sequence ID" value="XM_040772307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G560"/>
    <dbReference type="STRING" id="1858805.M5G560"/>
    <dbReference type="GeneID" id="63687369"/>
    <dbReference type="HOGENOM" id="CLU_021713_3_3_1"/>
    <dbReference type="OMA" id="NQIKWCR"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000174">
        <property type="entry name" value="Protein phosphatase PP2A regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000189">
        <property type="entry name" value="Protein phosphatase PP2A regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01025">
        <property type="entry name" value="PR55_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="451" mass="51103" checksum="89F68BE07AB7CCBA" modified="2013-05-29" version="1">MDGESSTSATANASNWRFAQCFGDKGEVDDITEADIISTVEFDHTGDYLATGDKGGRVVLFERNDSKKGCEYKFYTEFQSHEPEFDYLKSLEIEEKINRIKWCKRQNAAHFLLSTNDKTIKLWKVFEKTLKVVSENNMNDGTRPVAPPTMATNLRLPRMMQHDSIVAAVPRKVYANAHAYHINSISINSDGETYISADDLRVNLWNLNISDQSFNIVDIKPANMEELTEVITAAEFHPIHCNLFMYSSSKGTIKLADMRESALCDRHAKLFEEEEDPSNRSFFSEIISSISDVKFSRDGRYILSRDYLSLKIWDVNMDRGPVKTIQIHDHLRGKLCDLYENDCIFDKFECTWSGDGQSVLTGSYQNYFHIYDVNTTNDIVLQADKSAFKAKKIGAGAKPGMKNGAKPGAKDSINLDAMDFNKKILHGSWHPRENTIAIAATNNLFIFAVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5D7</accession>
    <name>M5G5D7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dolichyldiphosphatase</fullName>
            <ecNumber evidence="6">3.6.1.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_77695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14385"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="EC" id="3.6.1.43"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dolichyldiphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.43" evidence="6"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630788.1">
        <property type="nucleotide sequence ID" value="XM_040776284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5D7"/>
    <dbReference type="STRING" id="1858805.M5G5D7"/>
    <dbReference type="GeneID" id="63691346"/>
    <dbReference type="HOGENOM" id="CLU_074922_0_0_1"/>
    <dbReference type="OMA" id="LTVYQHE"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047874">
        <property type="term" value="F:dolichyldiphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03382">
        <property type="entry name" value="PAP2_dolichyldiphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039667">
        <property type="entry name" value="Dolichyldiphosphatase_PAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF1">
        <property type="entry name" value="DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="54"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="240" mass="27685" checksum="A8500DFE7C624044" modified="2013-05-29" version="1">MAGQHQQAALESLSLTHILYDPDDPVGRIFALLALSPMILVSMYTIVVLLRRELLISTMFAGQLGCEAFSWMLKRMFKRERPIDYVGTGYGFPSSHSQFMGYFVTFFLLHLWFRETSMERLQDPLSKVRKMILYIGVPIWGAAVCYSRFHLTYHTVSQVVVGATIGIAIGAGWYLLVEAIPVFYPSSLLGQWRTWFLESDVASRFRIRDSWAVWPDGGTDAEWGVWKIEWDRSRREKKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5F6</accession>
    <name>M5G5F6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">BAH-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_110317</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
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        <subcellularLocation>
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    </dbReference>
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    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
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            <end position="491"/>
        </location>
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            <begin position="114"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="311"/>
            <end position="350"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <end position="568"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="665"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
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            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
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            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
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            <dbReference type="Proteomes" id="UP000030653"/>
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    <sequence length="693" mass="78384" checksum="C99C4C1BAC58FED9" modified="2013-05-29" version="1">MPLLPTQSVACYSVISTLTSHRENRRNLSAQFTELPDKNEYPEYYRVIPEPRSLSGIKASDSLDKGRYNSTDEVWSDLKLVFLNAMHYNEEGSSIWRNAKTLETLLTKAWVNTSGLPDPPPSPPPGVSYPMQPVRTPMTAAKSRKRRTPPPDDEALAASEEKQAEKQVVLAQSDEMVRRVEESMEKWPGYGDVGWMGQPLGDPFVMYRDILQQIRDHQDEKRERISKVLDMLPDDSDIPYLSYNPTFMQGLLSLKTIEAQVERHQYNSSAEFDQDLTRLFEKGRRFYEPGSEDYGKVILLQRMYHQLTAPDASSSTGNNFASVAAGPGNAKPLRSAESTNEDGVTSFRISSKERQFTDSASFKGQIYRVGDYVHLMNPDDPAKPIIAQVFKTFLPDGASLEQNQPSLTVCWYYRPEQTIHPAHRQFYMNEVFKTSHFADHAIGDVIEKIGCQFTTKYTRGRPKAPYWYPGWPLYICDSRYNDKEKAFVKIKNWNSCIPDELRKMDFMPVQPFERTIVLRRVPSPFLIGGKGPGKIGEPEAAQLREDDSEKERDRDTKRKRLDTQPYDTQSRAAAATANIFQWGPTAAERKSAEDRTVITAAGGAGQLQASGVVIETLPPETVMHFARDLETGSMLWFAGPPMLMARARPLRHSLAYLAYKATGVKPRRDDGQDRAAAMEMEEAEGGERSMVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
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    <name>M5G6D0_DACPD</name>
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        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="1" type="ORF">DACRYDRAFT_115090</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="327" mass="37073" checksum="9DC895D9BDB87CD2" modified="2013-05-29" version="1">MPGPPMLHYNPADNNSYDWLSRVPHDVWHYLFALCFDQDQGNGILSLMFTCRYMHEIGVNYLYSQANIFFSGLDGNLVQYTRGNYLAASEFVLRHCKAIRDVMLLCDDEPFLPRFSFVSTIPHLRSLNLVTLDITQDVHTFLLGIPNLSSLGFLRCWIEAGNNLFELPPQQHVGLQCLEVSTLNVAIRDPFGEDIACQEFMAFWTAWVGPSLNMLDFEGPLFRVFGHDEINHYDRASRNLRFLEPLFASIPATITHLKLSLTAMDSEALAGLLAKLTNLRAFICTQHSPDLPAALSRPVWSGLSNLTWVSVTPEYLQIIWPLAYATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6E0</accession>
    <name>M5G6E0_DACPD</name>
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        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="1" type="ORF">DACRYDRAFT_23903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT99332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773452.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63688514"/>
    <dbReference type="HOGENOM" id="CLU_597193_0_0_1"/>
    <dbReference type="OrthoDB" id="3247499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51776" checksum="5EEF0F391DC8774D" modified="2013-05-29" version="1">MLSSPLDRVPNEIWFDIGKLLRRDRPTLLSLSQTCKRLRSLTIPILLYHVDLDLIESPGRAASLLAMLGDESEAGRFVRRMHLRISVLLLPKEIWRLLKVIAVEDLVLSSSIISKTFFDAILAIPSLRSLAIQSCTIFPKDRIHTAVADNRCGGKQLVSLEISWQETSRTPTSAAILSHVNVTNLHKLSLDGAAYNSSAALDSLHIISGTCLTSLRFPLVERASQNGDPYLLLHDTLINQSHIRLLHLHPKVHISSIPPDALPLLEEFKGSCELAEMLVPGRPVTWLSITTTSKFGDQQGDMQETFQAFTKSSRHLLFLEFEEMYVDEEWIVDLPRLFPQLEELRVQSTNYISKGFLGNAMPTHLSKMKACKSIRFRCRGGGSHPLNLLYMPDDANAKWAEQTVLRWGQRNPTLQEVWLGRLSLLKVAPNEWKIYDEFHFRGPAEAYNIPLLLPDRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6I1</accession>
    <name>M5G6I1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631198.1">
        <property type="nucleotide sequence ID" value="XM_040772119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6I1"/>
    <dbReference type="STRING" id="1858805.M5G6I1"/>
    <dbReference type="GeneID" id="63687181"/>
    <dbReference type="HOGENOM" id="CLU_058671_0_0_1"/>
    <dbReference type="OMA" id="FGVMSLY"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="281" mass="30752" checksum="CEE11D26DAB0C879" modified="2013-05-29" version="1">MSSYPVPPPSYQAPPSPSKNYGAADETQQALLGEGVATTSTAARNAIFDQPAADDLPDDFKYGTTVSESAVEIQQAFVRKVYSILFVQILGTVIVAAGMRTEDAMFFVKQHPSVVIVPLFGTLINLGVLFWKRHSHPLNLVLLATFTLMESVAIGAAVAYYDQVVVMQALLITLGVFLGLTLFTLQSKYNFDSMGPFLFAGLLVLVFSGLVHIFLPFSRGVDLAYGIGGALLFSGYIVYDTHLINRRLSPDEYIWGAIALYLDFINLFLSILRILNNANHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6L7</accession>
    <name>M5G6L7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Adenylosuccinate lyase</fullName>
            <shortName evidence="12">ASL</shortName>
            <ecNumber evidence="6 12">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20907</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="6 12"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631238.1">
        <property type="nucleotide sequence ID" value="XM_040772136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6L7"/>
    <dbReference type="STRING" id="1858805.M5G6L7"/>
    <dbReference type="GeneID" id="63687198"/>
    <dbReference type="HOGENOM" id="CLU_030949_1_1_1"/>
    <dbReference type="OMA" id="VQENAMK"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.60:FF:000001">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000005">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="13">
        <location>
            <begin position="354"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="464" mass="52322" checksum="9AB87944526321CF" modified="2013-05-29" version="1">MAYLFSPAMRFHTWRKLWLNLAIAEKELGLNISDDAIKEMEANLFLDVDQFKVAAQEEKKRRHDVMAHVLTFGTVAPAAAGIIHLGATSCYVTDNADLIFMRDGCNLLLDKLAVVIHRLSAFAAQYRALPTLGFTHFQPAQLTTVGKRATLWIQELLWDLQAIERARDDLGFRGVKGTTGTQASFFTLFKGDHEKVKALDKRVTELMGFKYAYPVSSQTYSRKIDIQVIAPLASFGATAHKMATDIRLLAHLKEVEEPFEKDQIGSSAMAYKRNPMRCERVCSLARHLWALQNNTFTTAGTQWFERTLDDSANRRITIPEAFLTTDILLTTLQNITEGLVVYPKLIASRISQELPFMATENIIMAMVDKHNADRQECHEAIRVLSHQAAKVVKDEGGQNDLVERVRKDPYFTPVWPELDSLLDASTFIGRAPEQVDEFIAEWVEPALKPYEKVISGAKAVELHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6P8</accession>
    <name>M5G6P8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6P8"/>
    <dbReference type="GeneID" id="63683640"/>
    <dbReference type="HOGENOM" id="CLU_262390_0_0_1"/>
    <dbReference type="OMA" id="ISCHIRI"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        </location>
    </feature>
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            <begin position="457"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="625"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="873"/>
            <end position="883"/>
        </location>
    </feature>
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        <location>
            <begin position="936"/>
            <end position="949"/>
        </location>
    </feature>
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        <location>
            <begin position="950"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1139" mass="125082" checksum="CEA231BC2C430103" modified="2013-05-29" version="1">MNSIFRATSRLFFRSTPVASSVGLSHADSPSLAPHTSPAVYPRTPGGRALGVTVDSGRIGTLSVHGRKGQIIGLYPVDHIVTRIGSDISCHIRIYEATMPHFACNLRFDVETHEVHLDALHHSYKRNNIPVSISAMQGPLADGERISVLGHKFTWKYADDVKELTEEMLDMSVPGLRGFRMTIVSSFELQRHRAVNLPEFIAPAHSSKRLHRNTFPRGVESAPLAQSTPARVPRRGYRAPDDTPDSHLGDVSINSATSSVYNSDSSMHFGLTQDGDCYVALEEVDEATEPKDERTPHWVHKKISDRLVRRAGSVFSIKRMGDYVESQARQTPRPSRKLHVLDKTHVKYIPYCPEERKKSPEFDRASPTTPPHSSSYGPDKRLSDGFTVNQVEGPIAISTERSVVLRDQVLPRIENTILTTDDRPSEFVSNQAVVSSLGEGPSRRRRLLSTPARPAHTPSQGLFRTSTPRIASSYYHAPIHPGDTARPVPFHLRPDEQIILMHFDQAAQGWSTNNDQMAEEEDWPMDIDPPELPEAQIVQQVISNPPQQAGPSNSSLIPYMSPSRVQAVQKSRRGWTSTDSMSTNRRQAAQPYPTQITAEQRSKWKKDMLRNLEKKRRKENRKAQADANAQAQAQAQSTVQVEASETLRLEDDIIVAEDILSNSKTDTPLGSVNSDVDHENEIDKGESISSGERDDTLLVCNDPVAAQVAPPTIQVLDPVDTPEPQITSPPQPQITSPPTSLPAANASQGDPVKAAPLDTEMNEMLVSNLEQTTNLQLPEDDAAPTAGPTRRGSKRKVQDSTEPVDVPRATKVSRTAMGRKVKEVVPDVEATTVEAILEQPEADTNGRPTKTLPRTRKNVSKVVSEDSREATQPRCTTRSMTKNSGAAAVVSAGVQGNPASGQVQKLDTVLAPDQVAMGGQQAAAPEDAIPPEYLQLHRRPTRALRKKPRTASNIAQTQPLPVPVVHTRSTRRSKATAEPPVAQPLGDEDGVQEQPSAPGHGTVRQQTVPQKKSAKVTGKRRRAVEDEEPPAKSAESTGKVVVEDRVVNTADELPVPNSSKRRRTSRREPIVVEEPEEKPVRPTRRSRKPSTPAIDAPAQDAEIPSGRRTRSWAARNAGVQEAAVLPDPVPVRKSRTARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G746</accession>
    <name>M5G746_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_98848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040777552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G746"/>
    <dbReference type="STRING" id="1858805.M5G746"/>
    <dbReference type="GeneID" id="63692614"/>
    <dbReference type="HOGENOM" id="CLU_030880_3_1_1"/>
    <dbReference type="OMA" id="WPFHDLT"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF4">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="368" mass="41125" checksum="0DFAF4E1FC79AD32" modified="2013-05-29" version="1">MNLLGQRWVRISHITSGLARGLQTQALKKSSLAFCFDVDGVLLHGHEAIPCAKKALRMVEGENSRGLKIPYILLTNGGGKPEAERARSLSEVLGVNISEHQLIQAHTILRPIAKKYGHEPVLILGGELDTCRKIAEGYGYTQPSLPIDYLATDSRIWPFYKLNDAENEIAKPHPPHPKFVLTVHDPRNWALEIQLLVDLLTHPTHPPPKIVFCNPDLLWRSDYPRSRFGQGAFRTALTAAYRASTGKKLEYEQFGKPTRATYEFAEGFLMDQAGIEVGEEMPRVYMVGDNPESDIAGANAHGWESILVNTGVYNSADDGPPVHWPTRMLDNVEQAVEWAIDREFAPLGEKLRERKKWDGVKSGALDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G781</accession>
    <name>M5G781_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630954.1">
        <property type="nucleotide sequence ID" value="XM_040772053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G781"/>
    <dbReference type="STRING" id="1858805.M5G781"/>
    <dbReference type="GeneID" id="63687115"/>
    <dbReference type="HOGENOM" id="CLU_399019_0_0_1"/>
    <dbReference type="OrthoDB" id="5419821at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="GmrSD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="GmrSD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GmrSD restriction endonucleases N-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="690" mass="77425" checksum="313B0766FD3AF1C0" modified="2013-05-29" version="1">MARPDDSFTTPPASSDDESLSDASWSDVDDDDDDMDFLNDAGSDLEEGEESKPERRPRSKPKPAPRPQRSPSKAGNGKGKGRADAPSAGKNEFVGHRLNKPVVVQVSCKMLFEEMKSGEIDLNAEYQRDVVWPEKNQSKLIDSILRNYYIPPVVFSKIDKGMNEVKICVDGKQRLTSILKFMNSEVHYISRKTGHKYYWDRVRGVKGAQILPDAWKSEFERAQMTTVSFTDLSPYEERDIFQRVQLGMALSTPEKWQALQGPWPDFMRQLRLSYFSNENRDSNILDNIQWDITRAKDFQDLVRMTFMVNATIVTHEPPPISSEKLEEAMSDEQGPSDKFQIQMATILATFLRLVKTEQYSHAFYGKVAPVELVMIAVLIGMCMDHVRDTDLAEGIREMRDNVRRTTAKGYIMWKPEVVKKMLRFIEAWKREHSRKVDRKSVSSYQSRVDVASNNDVSRNDVSRKRNASAAHEDSSDEERRRTDRNVRPRSSALADTKIPKKTSTSTSTTTNAGSGSRTSSAQAGPSGTHAPQRVAPPPLVSRETLLSQAGVRSTPTSNSNRQNSSGSSVQERSPVETRCPTTVLAPSTASNGIVVRQQRPPTTVPAPITASNGIVVRQQHPAPAAIADMDRATMEQEIDRTTEEITALSVLVARGDRPDHAELAARLRQLTSLKTQLLKNKFLGRNFRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B9</accession>
    <name>M5G7B9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626560.1">
        <property type="nucleotide sequence ID" value="XM_040773360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B9"/>
    <dbReference type="STRING" id="1858805.M5G7B9"/>
    <dbReference type="GeneID" id="63688422"/>
    <dbReference type="HOGENOM" id="CLU_012236_1_0_1"/>
    <dbReference type="OMA" id="GYTTLCA"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="438"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="647" mass="70489" checksum="3A06E7686C89ABC7" modified="2013-05-29" version="1">MTPTVAPYGTWKSPLTADALTASSTTYTALAADPSTKQIYRLESRPSEGGRSVVVSSSLDDLTKEKDVFGSGWNARSGVHEYGGGALWAEQGIVFFSDYGSGRIYTVKDGQVEAFTPENKNFRYADFRPYPDNPNILVSVMEDHTKPAPADVVNTIVLLRPGEAPQPIATGADFYSSPRWSTDGKWLCWYQWMHPNMPWDGGLLKLAQVSSSQSNISIEETRTIAGVDGQVSIAEPTWISPTTLLFQSDVSGFWNPWSYDVTTGKVGPLLPEPIPQEFTAPQWTFGISNIAVLSPDIALIISVDQGIHRLNLLTLCPAPKYKRLDVPFVAMTQLYPISATQAIMLGATDTTPLSSILLTLVGEQVNYQTIQSPSIVDFPTELFSGAEAKTLRTPDGPVHILYYPPRNPEYVSPSGERPPALVSVHGGPTGAAQPGLNLGVQFFTSRGYAWIDVQYGGSTGYGKAYRDLLNGQWGIVDVRDSAACVSALADEGLIDRKRVGIRGRSSGGFTVLAALCDYSDIYTAGVSLFGISDLKALAGETHKFESRYGDKLLGGTVDETQEVLRDRSPINKAEDIKAPLLLLQGSIDPVVPPKQAELILRKVQERGGVVDMVVFDGEGHGWRKAETMKEAAERELNWYEQVWGLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7P6</accession>
    <name>M5G7P6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_60848</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633110.1">
        <property type="nucleotide sequence ID" value="XM_040775651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7P6"/>
    <dbReference type="STRING" id="1858805.M5G7P6"/>
    <dbReference type="GeneID" id="63690713"/>
    <dbReference type="HOGENOM" id="CLU_025086_2_0_1"/>
    <dbReference type="OMA" id="QIEGWVM"/>
    <dbReference type="OrthoDB" id="238316at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2320:FF:000001">
        <property type="entry name" value="phenylalanine--tRNA ligase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040725">
        <property type="entry name" value="PheRS_DBD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18553">
        <property type="entry name" value="PheRS_DBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="236"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU06216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="507" mass="56408" checksum="CDAFEE0A1D15E585" modified="2013-05-29" version="1">MDSSELQQLVVDILEKETAIPDTRKLVIPGTKRQAASAEDQNAVISALASLASREIVTYDQKDAFTYLLTAEGAQIARDGSHEALVWAAVPPKDSGETMTIKQLQESLGQAAKIGQGKAFKNGWVGKDRDKLFKLVAKIVDTTREELNEVEKTGTLKGGEKAVAELRKRKLLDQKKSLWCTVKKGPAFTTDLRKPETDLTAEMLATGSWKDSTFKKYNFDADGTPTNGGALHPLMKVREEVRGIFFEMGFAEMPTDAFVESCFWNFDALYVPQQHPARETQDTFYVSSPLRGLSPPKDYLDSVAQYHSRGSSDGSSRGYQAPFSKEESHRLLLRTHTTSCSARMLYALAQKGKKDGFKPAKLFSIDRVFRNEAVDATHLAEFHQVEGVVADRGLTLGDLIGFMQTFFAKMGLPNLRFKPAYNPYTEPSLEIFCWHPGLGKWVEIGNSGMFRPEMLEPMGFPPDVRVHGWGLGLERPTMIRYGITNIRSLVGHKVSIDGVEKSPAVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G883</accession>
    <name>M5G883_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase V0 complex subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_104867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631868.1">
        <property type="nucleotide sequence ID" value="XM_040767992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G883"/>
    <dbReference type="STRING" id="1858805.M5G883"/>
    <dbReference type="GeneID" id="63683054"/>
    <dbReference type="HOGENOM" id="CLU_170555_1_0_1"/>
    <dbReference type="OMA" id="WAITYLC"/>
    <dbReference type="OrthoDB" id="1508846at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="77" mass="8700" checksum="545BAE1743910765" modified="2013-05-29" version="1">MSGWVVIIILAIAVAAGFVGWWLTPKGDQQTLIRTSILLTIACCYLMWAITYMAQMNPLIAPRRSDLRFDTAERRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8B8</accession>
    <name>M5G8B8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_109428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
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                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
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        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
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        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
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    </dbReference>
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            <begin position="456"/>
            <end position="480"/>
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    </feature>
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            <begin position="62"/>
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        </location>
    </feature>
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            <begin position="24"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="502" mass="54443" checksum="7A37244931EEDD31" modified="2013-05-29" version="1">MTASAATIHSERTPLLSSTERDSSPPTALTTSDASTLVDGPPDVDPPSPAEDDEDRPLPLWQMFLLCFARLVEPVAFFSIFPFVSEMIHESGSVPDAEVGFWSGWIESCFSLTQTVFMLFWGRASDKYGRKPVLIASLSGVAVASVLFGLSKSVWQMIALRSVAGIFAGTIVTVRTMITENSTQKTQARAFSFFAFAGNIGIFLGPVIGGGLSKPATQLPAVFGGSWLLREYPYLLPCLISGGLAAVAAVINLIWLKETRKLQKDHHAIVLTPPSMREVVSGPGVIPVLCIFEYALLLGVAFTAMCPVFFYTPIELGGYNFTPPQISLYLAIAGISQAIWLLLVFPPLVNRIGTGKLLRLCACAWPITFMALPLMNILLRHGQWTAFWVIMPMIIITSSGVSMAFTAVQLALNDISPNPLAHGTLNGVALSLQSAVRAVAPATYNTVYAIGVERQILWGELGFAMLIVTAFGFIVLLKWLPEQAEGRPKKKADEETQREEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8D0</accession>
    <name>M5G8D0_DACPD</name>
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        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
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            <begin position="15"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="68"/>
        </location>
    </feature>
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            <begin position="152"/>
            <end position="519"/>
        </location>
    </feature>
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            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
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            <end position="223"/>
        </location>
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        <location>
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            <begin position="367"/>
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        </location>
    </feature>
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            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU06471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="519" mass="55401" checksum="363E14AA1ADB0DBB" modified="2013-05-29" version="1">MAAVSPLLLPSSGTHPVRIGTSLKRKFASLDADSNPGGRRQRQRRELPESEFHAVQFGRQPESVDPASGSMFDTTGGAGDGSSKIQVERQSATGERFLFTGTQTASKLRDCLLLWDPNTNSFTLEVLSSSTTLAYDRSATNVLRRQQGIEVSLTPSAGGSGSGSGGSAVQPPAVGGDEPTPLDLGGYGDADMDAEADADAEGDPDVDEEPSPVNRNTNTSEETYVNADLDPDLEEPELQAYRPAPAPVLRQRQPPRTIPAYEEIDMRAGYVSEDSDLLAEGDGDVGDVGDLDADGVTDADAEGVTDDAEAEVEVEPTAHEQEQDADEELDDFLLADLTAHQEEEEEEPEPEPTPVPEPEHRSRRGRSSTSHAHAAPTQPPVPPTRPQPPALRTLALPTARRMSLRSATTQAINSVSSASTLPSPGTAVNGANGAEKKWDDDSDSDSEDDEDDEEEGDGEDSEFDFLAAELNDPGQEEQSQAPAEGDEDWEDVESGQSPLAGQSRSRGRQLDIWGDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F8</accession>
    <name>M5G8F8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein-like 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_45334</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633395.1">
        <property type="nucleotide sequence ID" value="XM_040774637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F8"/>
    <dbReference type="STRING" id="1858805.M5G8F8"/>
    <dbReference type="GeneID" id="63689699"/>
    <dbReference type="HOGENOM" id="CLU_2746986_0_0_1"/>
    <dbReference type="OMA" id="RGTTHER"/>
    <dbReference type="OrthoDB" id="10266128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014813">
        <property type="entry name" value="Gnl3_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08701">
        <property type="entry name" value="GN3L_Grn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanine nucleotide-binding protein-like 3 N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="82" mass="9343" checksum="7D46A012B45EC925" modified="2013-05-29" version="1" fragment="single">ESSKRGTTNQREKIKRKVAEHRHKSKKEAKKNVQWKSRKQKDPGIPNSMPASMRAQVLAEVAEQRRIVGDLLPSIGPRSELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8G4</accession>
    <name>M5G8G4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631344.1">
        <property type="nucleotide sequence ID" value="XM_040771039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8G4"/>
    <dbReference type="GeneID" id="63686101"/>
    <dbReference type="HOGENOM" id="CLU_060803_1_1_1"/>
    <dbReference type="OMA" id="FWISSAK"/>
    <dbReference type="OrthoDB" id="2562239at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="28881" checksum="0125237108BBF834" modified="2013-05-29" version="1">MSGNTDPYSTIGSLPNISGGIPTSPDFAPSILFCLLYGILLPPCIWRTYTYRKPGRLMWTFIRLIFFALMRIATFGLRVSEAHSASLPNNPVPNLGTFIAEQVLLGIGFIILADLMIELLKSHMWRTDVPPAGETRWAHPAGHHVLKRIVRIMHLALIVAIALGIAAAAQYSSAINSPSIASEVQTLRIVSVALCLAVCALLILVSLLLLTHPSLGLSHTIYLLVINCILVIIPSYRVSSVTDSPSISALVGAGTQVKFYILQGAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8H4</accession>
    <name>M5G8H4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="12">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ALA1</name>
        <name evidence="14" type="ORF">DACRYDRAFT_20988</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="12"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8H4"/>
    <dbReference type="STRING" id="1858805.M5G8H4"/>
    <dbReference type="HOGENOM" id="CLU_004485_5_0_1"/>
    <dbReference type="OMA" id="NKKDNFW"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.130:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="13">
        <location>
            <begin position="14"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="727"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="731"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="960" mass="107470" checksum="CE5FF95EB9F4B46F" modified="2013-05-29" version="1">MSTLTPFGGPYGHWPADKVRQTFIDYFKARGHTFWPSSSTIPYEDPTLLFANAGMNQYKAIFLGTVDPQSELAKLKRAVNSQKCIRAGGKHNDLEDVGKDTYHHTFFEMLGNWSFGDYFKKEAIQWSWELLTEVYKLPKDRLYVTYFEGDSKQGLDADLEARQYWLDVGVPEDHILTGDAKDNFWEMGATGPCGPCSEIHFDRLGGRNAAHLVNQDDPNVIEIWNNVFIQFNREEDGSLRELPAKHVDTGMGFERLVSCLQDLPSNYDTDVFVPIFAKIQELTGARRYAGKLGAEDVDGIDTAYRVVADHVRTLTFALSDGGVPNNVGRGYVLRRILRRGARYVRKKFGVPIGSFFSSLAPTVIQQMGHFFPEITRKLSDIKEILDEEEESFSRTLDRGEKLFEEYVTATKKKGSSSLHGHDVWRLYDTYGFPVDLTRLMAEELHLTINEHEFEEARLRSLEASKASQKKGNEDAVKLDVHDLAALESNPKVPKTDDRPKFGLGNISATIQAIYFNKSFLESTTAIPEDAAFGILLDRTSFYAESGGQENDTGSIIIDGKTEFMVQNVQVYNGYVLHSGALKYGQFSVGDEVISSYDELRRWPLRNNHTGTHILNFALREILGDHIDQKGSLVAPTKLRFDFSHKAQVTLEEMEKIEEICNGWIKRDVKVFSQEVDLHTAQEFAGVRAVFGEAYPDPVRVVSLGYEVQDIIQDPQNPKWRGTSIEFCGGTHVAKTGDIKALVLTEESGIAKGIRRIIAVTGEEANEVNRLADSFETRLIQIERSAGKEKDAALKAYTFELGQADISALRKAALREKFAGIRKTFDDANKAHLASLTKELTKTIDKHFQEKPNESVYLANIDSLEGNTKIMQSIVQHARTLNKAVYIFSVDVSAGKVAHVNFLPKHAITQSFSAKTWANAVSVILGGKAGGKDDVAQGVGVNVEKVDEALQLARNLYHRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8M1</accession>
    <name>M5G8M1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627015.1">
        <property type="nucleotide sequence ID" value="XM_040773305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8M1"/>
    <dbReference type="STRING" id="1858805.M5G8M1"/>
    <dbReference type="GeneID" id="63688367"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="CNIAIPS"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="264" mass="29220" checksum="74552A21B3D436D7" modified="2013-05-29" version="1">MASRSPERAETAIADLKMITKKDDIHFIKLDLADLENVKASAAEFQSKEKELHMLFNNAGVMSTPMHMLTKQGFDMQFGTNVIGPLYFTKLLIPTLLETAKTTPGGKVRVITTSSNGHYGAFKGGILWETLKDGPERNKKLSRTTAYFQSKWGDVVFANELARRYGDQGIVSTSLNPGLVDTELGRYIPAWFASMMGFVKLILNRADPDGAMTQLYAGTAPETASANGKYFIPLAREGIPREDTHDEGMGKKLWDYIDEVTADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T3</accession>
    <name>M5G8T3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methionine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_113983</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631484.1">
        <property type="nucleotide sequence ID" value="XM_040769735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T3"/>
    <dbReference type="STRING" id="1858805.M5G8T3"/>
    <dbReference type="GeneID" id="63684797"/>
    <dbReference type="HOGENOM" id="CLU_009710_3_2_1"/>
    <dbReference type="OMA" id="HLNTTEY"/>
    <dbReference type="OrthoDB" id="5844513at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036464">
        <property type="term" value="C:cytoplasmic ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.20:FF:000001">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000037">
        <property type="entry name" value="Methionyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="entry name" value="Methionyl-tRNA synthetase, Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="Methionyl-tRNA synthetase (MetRS), Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="31"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="15">
        <location>
            <begin position="461"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="600"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU04590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="687" mass="77117" checksum="BEFB8F6E61480F18" modified="2013-05-29" version="1">MDKTIREEDGLLMRKFTPGEEVLPVAGEDNILITSALPYCNNVPHLGNIIGSTLSADCFARYCRSQNRITAYVCGTDEYGTATETQALKEGITPRQLCDKYYLLHKETYDWFELSFNHFGRTSTPQHTVISQDIYLNLYKNDLLEKETNKQLYCLNDEKFLADRFVEGTCPYCGYEDARGDQCDNCTRPLDPIELINPRCKIDKSHTVTTRTSDHMYIELNKLQPQLEVWIKESWKKGKWSSNSVINSEGQFIDARLKQGLRPSPVTRDLQWGVPVPEAPGHDDGMKGKVLYVWFDAPVGYPSITSTWINDNWKKWWFKPDDVKLYQFMGKDNVYFHIVLFPSMLIGDGRPWTKLHHISTTEYLNYEGGKFSKSRGVGVFGPDARKTGLPASIFRYYLLSARPETGDTMFSWGDLIAANNNTLIKNFGNFINRVLKFVAGKNYGGVLPDSKDQPGPLSVETDVDAAFVKDINALFTVYIETMDSVKLRQGLALAMQISSRGNQYLQDSGLDNTLFNTQPERCAQVILRAVNLIYAISAIIFPFMPAISATILEQMNAPARTVAKQLSIDILPGHQIGKPSPLFKLIDEKKADEWRNMFGGTRTPAHAPPPEPGVSKRKAASGKKAATVKTDGPKSPELVELEGKRDKQAQLVREIKAGKGPEGVDLQEALAQLLRLKASITEVEVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9B1</accession>
    <name>M5G9B1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_114122</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631694.1">
        <property type="nucleotide sequence ID" value="XM_040769766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9B1"/>
    <dbReference type="STRING" id="1858805.M5G9B1"/>
    <dbReference type="GeneID" id="63684828"/>
    <dbReference type="HOGENOM" id="CLU_038617_1_1_1"/>
    <dbReference type="OMA" id="FINEHAG"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00238">
        <property type="entry name" value="ERp29c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02998">
        <property type="entry name" value="PDI_a_ERp38"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1150.12">
        <property type="entry name" value="Endoplasmic reticulum resident protein 29, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011679">
        <property type="entry name" value="ERp29_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036356">
        <property type="entry name" value="ERp29_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07749">
        <property type="entry name" value="ERp29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47933">
        <property type="entry name" value="ERP29 C domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067598" description="protein disulfide-isomerase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="130"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="42544" checksum="87D469C43BEF5716" modified="2013-05-29" version="1">MKFTYISLFAAFAATVLASNVLELESTTFDQHIGGDAPALVEFFAPWCGHCKNLAPVYEQLADAYSHTQKVIIAKVDADGAGKEAGARFGVTGFPTLKWFPAGSLEPEPYEGQRDLDALISFVESKSGVKAKGPPPPTRQILQSHDFDEVVMDPSKDVLVAFTAPWCGHCKNLKPTLEKVAQDFQSEPACVIAEFDADAATNKPIAGRYNVNSYPTIKFFPRGNDKVAEDYMQGRSEEQFVEFLNERCGTFRSSGGVLNSLAGRIPSLDSLASKFYSSIPDRDTLLKEASSAAAALELAQKTSGDYYLRVMNKVSESGEWLHKESARLASILQKKTLAPAKLDEIQRKANILASFVEEKLKEAADEAQHVFNAGSEKGAEATERVREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9R5</accession>
    <name>M5G9R5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase C-terminal-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_114323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631924.1">
        <property type="nucleotide sequence ID" value="XM_040769798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9R5"/>
    <dbReference type="STRING" id="1858805.M5G9R5"/>
    <dbReference type="GeneID" id="63684860"/>
    <dbReference type="HOGENOM" id="CLU_039475_0_1_1"/>
    <dbReference type="OMA" id="LWVHQLQ"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF263">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="30883" checksum="295DE10964CC8EF4" modified="2013-05-29" version="1">MSSPPHKLQKLAPYILHYWGGIPGRGEYVRLAFEYAGVSYTDSNDSAKLLKTLRSTSPSHFAPPMLELPNGKILSQTPAILNYLAPKLGLAGEKGNLLKNAVEDDDEREEAEFERSIVNQLVLTALDLCVEAHDSHHPIASSLYYEDQKQEALRRAEDFLKLRIPKYLAHFEETLRKNKVSHSHLVGKTTTTADLVLFHVVDGLLYAFPRRMGALDKGGKYKRVLKLHEKIMAEGGIKEYVESGRRRKFGVGLFRHYPELDGEDEDTIEPEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA84</accession>
    <name>M5GA84_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627695.1">
        <property type="nucleotide sequence ID" value="XM_040770337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA84"/>
    <dbReference type="GeneID" id="63685399"/>
    <dbReference type="HOGENOM" id="CLU_2196861_0_0_1"/>
    <dbReference type="OrthoDB" id="10560622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067705" description="CBM1 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11165" checksum="842B68AB442F902B" modified="2013-05-29" version="1">MKSFAVSTFAVLALALTTFAAPIAAPPSSDSFFGGGWLGSGKRDTVERAPPNPDCSFFGPCWTGGGKREAAPEPIPEPEPEPIPEPEAAPPKPDCSFFGPCWTGGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA2</accession>
    <name>M5GAA2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Ribonuclease H</fullName>
            <shortName evidence="12">RNase H</shortName>
            <ecNumber evidence="5 12">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19826</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="5 12"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632154.1">
        <property type="nucleotide sequence ID" value="XM_040771674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA2"/>
    <dbReference type="STRING" id="1858805.M5GAA2"/>
    <dbReference type="GeneID" id="63686736"/>
    <dbReference type="HOGENOM" id="CLU_030894_0_2_1"/>
    <dbReference type="OMA" id="IRSMTEW"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000002">
        <property type="entry name" value="Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="14">
        <location>
            <begin position="110"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="33527" checksum="FDB85ABEB8D9E7FC" modified="2013-05-29" version="1">MPKATKPQFYAVRRGQVPGVYRTWRETETQVKGYSGAVYKGFMTRAEAEAFVQSNLVPASTATSTSKNNPYTRPPTPRGPVAGVPTKVRAPIETGIEKNGEDGLEVVVDGKVWKVVYTDGACSGNGRAGATGGIGVYWGPGMKNISERLPGAQTNNRAELIALVRALETDPDPAAPLILKTDSSYSIQCMRDWLPKWRKNGFQTSKGPVKNKELLLYLSYLMEERPGHIRLQHVRGHAGVEGNEIADRLAVAGAGLPDVEERDWAITKEEAEEELSQEHVDFEVPPEFVLSEAELAQMEQTQQFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAI8</accession>
    <name>M5GAI8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629861.1">
        <property type="nucleotide sequence ID" value="XM_040768207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAI8"/>
    <dbReference type="GeneID" id="63683269"/>
    <dbReference type="HOGENOM" id="CLU_520759_0_0_1"/>
    <dbReference type="OrthoDB" id="2447803at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="62285" checksum="8AD6D459D59B6E07" modified="2013-05-29" version="1">MKRGTTVCDLTSARWHSIWSIDELVLMIFEHCELRSAACLARTCHRLYTLGIPLIWTSPPLTALITLAESTADIFASSSRTHCNWKSWLWCNKPIPQPTNSPRSRRLKFFSQFVTDLILTDPSDSFESPEIEILLEVIQQESVESLFPRLQSLVIIIHRPEFLQCILPFASRNLSWIKIFLAPPNTDQVLGGSGYGIFLPHLCTLPRLDSLTLFGSDTISKDELHFISTILRTFPDLEAFDAWRMKADDEFFRRLSSTRNLVTLRIQLGLIVPTLDSVSLPHLESLIIEYSSNTDLSVLLDHLHAPVLRRIQLDFHWELGALAFDSPAGFNGPAYRLVSERIAASWSQSLEDLTISRVGQLQIEKESLRIWDMDSFRPMLSCHQLRKFLIAPPIRLDAQDADLVQIGQSWPKIRELSLTGYGSPISSRRPCAGAEGLLALVGNCHELEVLELSINLQSLGALIPNIKNWPEEYATVRNPNLRNLYVHDCLICDVDNTSMFVRRLFPNLETFRYARKELFPMSGNAPTESERMVCMQRIQKELGLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAK1</accession>
    <name>M5GAK1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_53415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627840.1">
        <property type="nucleotide sequence ID" value="XM_040775171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAK1"/>
    <dbReference type="STRING" id="1858805.M5GAK1"/>
    <dbReference type="GeneID" id="63690233"/>
    <dbReference type="HOGENOM" id="CLU_1393181_0_0_1"/>
    <dbReference type="OMA" id="KPQTSEW"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="19704" checksum="A22708D3F334396A" modified="2013-05-29" version="1" fragment="single">TSSGVWSTVGPGGKIAAAPAAVRPTPVAQASVSAARSPAALAQATTAARSVPTPQLAKTPAKVASPAPNESDPLVPSAEFMRWLRDALKGLNAGVNVDEYMHMLLSFALDPSPAVVEIIQESIYGNSSTLDGRRFAAEFISKRKADAALKKAGGSTARTSLADVVKAQPKPASPDWNFRTVVKKKGKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB06</accession>
    <name>M5GB06_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_113653</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632469.1">
        <property type="nucleotide sequence ID" value="XM_040769672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB06"/>
    <dbReference type="STRING" id="1858805.M5GB06"/>
    <dbReference type="GeneID" id="63684734"/>
    <dbReference type="HOGENOM" id="CLU_055188_5_1_1"/>
    <dbReference type="OMA" id="EPGWLVN"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="299" mass="32796" checksum="46F8B1ADAE0D1AC1" modified="2013-05-29" version="1">MNSILASWRALATVRNTATFVPRTFLDPTRSYATRPPAARITLGNLAPAPGSTKQRKRLGRGQGSGRGGTSTKGHKGQNARSGGPRPGFEGGQTPLTRRFPKRGFHNPGSREYAPLNLERLQFWIDQGRVEVHEDRAITATELVKSRVVHQMHDGVKLLGDGAEYFHTAINIIVSRASQSAIKAIEGAGGTVVCRHYNTLGLLDLKKGDMKHKLAAPMREKDILYYSNWRRNRGYLAIPPEIRARTAFSGSHLDVPEHLRVAPKEQKPQPVDPEAVMDAAQAAPPPPAKELESQPAPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB52</accession>
    <name>M5GB52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_99555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630131.1">
        <property type="nucleotide sequence ID" value="XM_040777599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB52"/>
    <dbReference type="STRING" id="1858805.M5GB52"/>
    <dbReference type="GeneID" id="63692661"/>
    <dbReference type="HOGENOM" id="CLU_075349_1_0_1"/>
    <dbReference type="OMA" id="EVNPNHG"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="209" mass="23933" checksum="30CC2D8EEC23ED58" modified="2013-05-29" version="1">MSFLRRLPSFLPSPSTSRALPITFIRSYAVPRPSAYTNPPPPPKVPPPNPDGTLRPHLGVVTSPNHGLFGFFHRDKDDKVVTLEMRDKRTEFSGRSWSAPELRRKSFLDLHTLWYILIRERNVLHTQLEEWKKVGGKPEHFANIDKLNNRCRKSLARIKAILNERRLAFKQARRITAKVEKNRINTERRWARKAAATAGEAGAPVAETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBI8</accession>
    <name>M5GBI8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_106332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630316.1">
        <property type="nucleotide sequence ID" value="XM_040768245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBI8"/>
    <dbReference type="STRING" id="1858805.M5GBI8"/>
    <dbReference type="GeneID" id="63683307"/>
    <dbReference type="HOGENOM" id="CLU_283849_0_0_1"/>
    <dbReference type="OMA" id="SGRNQMI"/>
    <dbReference type="OrthoDB" id="3366093at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005034">
        <property type="term" value="F:osmosensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006972">
        <property type="term" value="P:hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001402">
        <property type="term" value="P:signal transduction involved in filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067635" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="964"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1096" mass="109176" checksum="38D8D20DD514328E" modified="2013-05-29" version="1">MLSLSPLFLLALLCSHPIRGHAHSTHSSFTHSHARRSLHTREGPTSASYAREERRDVLDGLGQVVGGLLGDLGKTVADLGEDVGNDLANIKRRLQSWEKRDLLGDLDQTVGDVLGGLGDTVADVLGDGNGSSSDSGTSTGTSTSTGTNSGTSTPASTTDTPSATSRDTTSPTSSSDTSSPTSSSDTSSPTSSSDTSPPTSSSDTSSPTSSSDTSSPTSSSDTSSPTSSSDTSSPTSSTDSGTSTPSTDSSSPSTTNPPSTADPGTTAAPTSATDDSCNGVLGALGCGLSSLGGGAGTAVSNIVGVITSDAGAILGNNPTSTTNIPTTTAAPTTATDSSSPTSPTDTASAPPTITPDTPLTTAPDPPPTTTPDSPPTTAPDPPTTAPDPPPTTTAPSSPTSTADSCDGVVGELGCGLSSLTGGLGTGLSDIGNGATSILLGGAPTTTADIPTSPTDVASAPPPTSDTSTPTVTAAPPPTTDPSTPTLTAPPPPPTTAIAPSTDSCDGLLPGALCGLSSIVSQVTSDLLGNGTTSTDPPAPPTSVATDPPTSVATDPPTSVVTDAPPPTTSPAPPATATDPCAVLGGFGCGLSSIVSIVTSDVGNILNGTTTAPPANPTSIPDPPASSSDTGSDNAISTVISQFSSAINDATSAINEISSILLGSPTTTTAINTGSINFGAGNTSAPATFTAPGLGPSTASVTSASPTPSFSPALGSIFPGTSLVVSVSQPTTISTAQDAPLSEFSGLLTASSLLFSSNSVSSDSSSPTQTNPDVLPTTLTQTFGTPAASPFPSAIPAKILPPTSSGSQNSVSGAVAAGSTPAGTTLISILFAPQLNWVFVVNNVESASQLFAFCPVLLANALGIDTNDVQTVSLEAYQPANYDGDINELLTVYLAQIPDAYVPYLQAQVQTKNSPLYYSSTGTAHQLSEFIDPAFPVTALATAPSSGSLAASGSSTTSNNQRRDAIIGVVTAVGGILLLAALYFARRWYKRRQERAHQQLAMSPASSAISPIGGAGIGVAAAYVPERNSPSPDMMQERRRSFFFAEDSLRGYMDPAATRAVDPLHEYQSQQRGAHRTSPVTISQISQPILRQSSLNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC22</accession>
    <name>M5GC22_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_92508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate</text>
            <dbReference type="Rhea" id="RHEA:23048"/>
            <dbReference type="ChEBI" id="CHEBI:11047"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:24734"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633458.1">
        <property type="nucleotide sequence ID" value="XM_040777081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC22"/>
    <dbReference type="STRING" id="1858805.M5GC22"/>
    <dbReference type="GeneID" id="63692143"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_7_1"/>
    <dbReference type="OMA" id="NLMGAGC"/>
    <dbReference type="OrthoDB" id="339764at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047988">
        <property type="term" value="F:hydroxyacid-oxoacid transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08190">
        <property type="entry name" value="HOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000003">
        <property type="entry name" value="Alcohol dehydrogenase, iron-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000003">
        <property type="entry name" value="Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042157">
        <property type="entry name" value="HOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF83">
        <property type="entry name" value="HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="8">
        <location>
            <begin position="73"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="9">
        <location>
            <begin position="295"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU06564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="501" mass="53965" checksum="EBF7795E9ED4E531" modified="2013-05-29" version="1">MPPLPRAPRSSILRLLQQSQHTACPCHACRTSSPLSALTAQSHGVGQLRNMATPFEGVKLPEKEYAFEVAAANLRFGEGVTREVGMDLKNMGATKVGVFSDANVSQLQPVRTAIASLESQGVPYELFTDVSVEPTDASWRKAIDWSRTHDFSHFLAVGGGSVMDTAKCANLFTVYKDADLFDFINAPVGKGLPIEKVLRPLIAVPTTAGTGSETTGTAILDIPSQKFKTGIASRALRPILGIVDTLNTDTCPRQVHISSGLDVLFHSLESYTAIPYYERTPRPDNPLKRPAYQGRNPISDVFSMWALQQTVKYLPRVAKDQSDREAKNQMLLAATFAGIGFGNAGVHICHAASYPISGLNKTGPKWKHPEYLTPGPIIPHGISVALTGPAVFEFTAPSAPERHREAAAVFAGVPVTDPSIARVSDGDVGQLLFDSIARFLDGLGVPRGLKAVGYTEKDVSMLVDGTLPQRRVLDLAPGIGDVPGEDGREHLTRIIHASLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC32</accession>
    <name>M5GC32_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="17">SIR2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_21165</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630541.1">
        <property type="nucleotide sequence ID" value="XM_040772267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC32"/>
    <dbReference type="STRING" id="1858805.M5GC32"/>
    <dbReference type="GeneID" id="63687329"/>
    <dbReference type="HOGENOM" id="CLU_023643_5_2_1"/>
    <dbReference type="OMA" id="PTHEFIR"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007654">
        <property type="entry name" value="NAD-dep_histone_deAcase_SIR2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04574">
        <property type="entry name" value="DUF592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="16">
        <location>
            <begin position="145"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="488"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU03647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="532" mass="59884" checksum="052FE16BACBA7082" modified="2013-05-29" version="1">MASRAANGNMHTPVKPNVSIDDMPMSTDVGPGPQVKVSYQDSYSNELDDVAHSIDGSDHEYQQLMEEAMHAFTEEEVEQMMGFLKERGMMAFLQRYVGQLDIPPSKLLLAFGVLLAPDLRSQLTEEHYIALLKQAISRTLRDRERLSQYETIDDAVALIRNSKHILVLTGAGISVSCGIPDFRSTQGIYAQLRESEIGQTLADPQQMFDLKFFKENPSVFYSFAHRIFPSNFKPSPCHYFIKLLEDKSKLLRNYTQNIDTLETVAGVKKVLNCHGSFATASCITCGTQFPGEEIKEDIFAERIPKCTVCIGKGREAGKKKSKGKGKMKPWEEEVTDEDEYKSILKPDITFFGEKLTSRFDKALFEDREEVDLLLVIGTSLTVAPVSEILHHIPHSIPQIIINKTPVPHVNPDIVILGEADEAVRYLSYRLGWELPIPPSSEAAHKRPREDVPVPPERVGQTWIWTFGSADGGEWLEEVKEGKIRRYMLASSDDESGEDEGDEEVSGDYLRPPKGRDSEESDNSQASKRRRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC85</accession>
    <name>M5GC85_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633538.1">
        <property type="nucleotide sequence ID" value="XM_040771625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC85"/>
    <dbReference type="GeneID" id="63686687"/>
    <dbReference type="HOGENOM" id="CLU_2687777_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="8101" checksum="7E293526B6BD3E1D" modified="2013-05-29" version="1">MAHATRGQISDIAHQQSAYTSASVSARAVPNNNQLRLSLDSVLVRANRMKLLLSPLLFYNISACECKPRKCAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCB6</accession>
    <name>M5GCB6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_21228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630676.1">
        <property type="nucleotide sequence ID" value="XM_040772302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCB6"/>
    <dbReference type="STRING" id="1858805.M5GCB6"/>
    <dbReference type="GeneID" id="63687364"/>
    <dbReference type="HOGENOM" id="CLU_077208_0_0_1"/>
    <dbReference type="OMA" id="YTEWADG"/>
    <dbReference type="OrthoDB" id="67388at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2210:FF:000002">
        <property type="entry name" value="ATP synthase subunit 4 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0138">CF(0)</keyword>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="25909" checksum="AEF74C5EC08930FF" modified="2013-05-29" version="1">MASRLLTKSLRASASLARPQVAAALPRVAVSQSMRGYVEKQPPAERASAIIDALPGNSLITKTGSVVLGTGLAAAAISQELYVVNEETVVAVGFLILLTALGRGMSGPYGEWAKAEVAKIAGILNDARKHHTSAVQERIDAVNEMQDVVAITKDLFALSKDTAKLEGEAYVLKQKTAVAAEVKAVLDSWVRFEQQAKENEQAELARSVIEKVMADIQSEKTQREILMSAVAEVEQLVKSKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCJ9</accession>
    <name>M5GCJ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21316</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630816.1">
        <property type="nucleotide sequence ID" value="XM_040772337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCJ9"/>
    <dbReference type="STRING" id="1858805.M5GCJ9"/>
    <dbReference type="GeneID" id="63687399"/>
    <dbReference type="HOGENOM" id="CLU_006019_2_2_1"/>
    <dbReference type="OMA" id="PSHFIGN"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="661"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="836" mass="94128" checksum="A364626B3470C956" modified="2013-05-29" version="1">MDRTYNYRQFPTTVSEPSEAPIPPPSSSTRLNQKQSKACDACHRRKIKCNGEEEGPHPCSYCRKNGYECTYNHQPNKWPPSKAYVDGLEHRVGELERRVEYLKRELVRARSRPTYSTSSPESSVSGEILDKEQEAKEEDPETQAALEPLAQEYEDLMLGNAAGSPISQEPRMYHEKGSHFQVVNQQLVEIGSKSIDKNKFFQLRIRPECRVVDTNIFDEVNLRLDPPTWPEPDLAKLLIDTYFEKWNCVLPLLHKPTFLRQYADPKMRLDNNWVSVVFGVFAIASKLVDDPRALGPPDENGHYFDAGMKYFNEMRRIGSPLYAPPSLFRLQAIILFANYLCGHPLCPSVGWALIGLGLRYLQDAGMHLKKEWLQRAKAHPFDYEMRKRVFWILYAMERTMALEMDRSFCLPEHDYDIEPLLELDDDALDLLQQGQKDPVGFSQCIAAFNVRVYLLQIASHKRGEMQMLRHCNSNVSHREETYLYGVNIRLQNVKAKLDTDLIYQKDQADPERLLYSSLVHIQFHWVQLILYRPFFSKSQRMAHPEVPILAVSGASSREIAIALEGLRAKNMLRGRVNDASLAGFVAGSVLIMNMWEQKGLDGIDEVNLCLKALKSVEDRWQFPGLLYDVLKNFADIMTNVVTGNCPLLGDRPICLKLSSNSSHRPCDKDASEKPSSEDASSITDPGATVPTTIVSHINGNGGASTNSNQFGEFATFSMGAPDLFTPFSAVQTGSLFDTNIGSAGPTSTATNQPMFGEDGWLNHLDLNGQHGFMDPTFNEWLTSMIIASQETFPMDNAATSSAAGQSMFSTNDAANAIAASGDSTWNSPWWTFDQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN1</accession>
    <name>M5GCN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628770.1">
        <property type="nucleotide sequence ID" value="XM_040772739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCN1"/>
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    <dbReference type="HOGENOM" id="CLU_1001231_0_0_1"/>
    <dbReference type="OrthoDB" id="3353767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067653" evidence="1">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="278" mass="29035" checksum="0A13F897F3E2F504" modified="2013-05-29" version="1">MLTFLPVFAISVLASQLGARQSLPTGPHGTPGVLIQPAEGQVFANPGPMTIKYRTTSGGGYVTQSIQVNVQNPGPIGGGPEANMLNGLQSLNAGTDEYIEALIATPATFCGDQVILVFETQVTPNGTLVQFLSASPTVHFSCWGGDYPPPPTSHSGPQGTLLSPSANTVYANTDGAGVHIHFQYERSLQLDAVTVSLALELAQSFVSYTLASALGPTGGVLDGTIEQYFAAPGECLCGTFDLVIDETQLYQGGLITFQTYSVPLQFDCPPEVVAFCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCX7</accession>
    <name>M5GCX7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_52097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628930.1">
        <property type="nucleotide sequence ID" value="XM_040775081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCX7"/>
    <dbReference type="GeneID" id="63690143"/>
    <dbReference type="HOGENOM" id="CLU_073624_1_1_1"/>
    <dbReference type="OMA" id="CKCICFQ"/>
    <dbReference type="OrthoDB" id="2142503at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="13282" checksum="E5EAFA2E91FC7A67" modified="2013-05-29" version="1" fragment="single">ICFNNYTILPLLLPEDPTKPCLSCTKQWCLDQKLSICREAMLGDANPDTATGKEGDVDVRCFQRDSPRDQLTVTLFILIIVGLLIGAAARGKMMEVGIDPADAWEASRKWWEVCLPSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDH2</accession>
    <name>M5GDH2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629287.1">
        <property type="nucleotide sequence ID" value="XM_040767413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDH2"/>
    <dbReference type="GeneID" id="63682475"/>
    <dbReference type="HOGENOM" id="CLU_1796409_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067779" evidence="2">
        <location>
            <begin position="21"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="144" mass="16639" checksum="215B2F98C6A78E9B" modified="2013-05-29" version="1">MTQAAHWWIFYFFLFNLEEDARVGLDREIRERLEQVDMELPLRAWRVGERIVHRSQLASTAYPPNALSSKKRKRKDSDQGSQHENGKDEDESNESPDVSVPRPITGKDLALLCCDEEEDVESDPENDHGQKDAAVRMWRGLIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDK5</accession>
    <name>M5GDK5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629382.1">
        <property type="nucleotide sequence ID" value="XM_040768459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDK5"/>
    <dbReference type="GeneID" id="63683521"/>
    <dbReference type="HOGENOM" id="CLU_1360353_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="201" mass="22866" checksum="746E5754CB2C4C90" modified="2013-05-29" version="1">MDIDKDVTEQWMALHAEGRGMVEDRIITSLPVESLEKHLAIVHAPHGRLPGFYRKEYHAMRGEKFISPSTRDNYRTRHLAKCMFFELGHWTSLNKLWQVTLVVVRDSSINFDSGRLILLVTCNLHSSSHAVSFTGSVRISLQDHIMGTPTHTYIPSRQLGGTRRTFSEPLRLDEVHSSAVLEYDLGIYTTDLLNLGELPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDR3</accession>
    <name>M5GDR3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631641.1">
        <property type="nucleotide sequence ID" value="XM_040771916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDR3"/>
    <dbReference type="STRING" id="1858805.M5GDR3"/>
    <dbReference type="GeneID" id="63686978"/>
    <dbReference type="HOGENOM" id="CLU_099163_0_0_1"/>
    <dbReference type="OMA" id="NMDYDKG"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="186" mass="20270" checksum="ED770CE75CA38B08" modified="2013-05-29" version="1">MNAQMANLAISLGGMQIARKIPMDKDPQILMYVRIGYVAAQLLCLAVYYYTSMKIKQKNDQTVLKYVEAKNPMSPDSGGLVTTTVRDYDLAEVSKAVRGVYMGVGMMAVLHLYMKFNPPLFVQTLTALKGIYDAKVVQIHLFGKAATGDLKRPFKVGGLFGAASDPATDAASIKEAESKPAPKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEC8</accession>
    <name>M5GEC8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HSP70-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_15053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630047.1">
        <property type="nucleotide sequence ID" value="XM_040771072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEC8"/>
    <dbReference type="STRING" id="1858805.M5GEC8"/>
    <dbReference type="GeneID" id="63686134"/>
    <dbReference type="HOGENOM" id="CLU_1151762_0_0_1"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="241" mass="26449" checksum="B040342B418324E8" modified="2013-05-29" version="1">MKAKRDAEAKLGFPVKDAMITIPTYFNDTQHQATKDAGTIAGLNVLRIMSKPMAATLVYSMKLPPKKNGQFILVYNLDRGIFDSTLMWMCGDDHDMQGTGGHGHLGGHNFDHAIAKYIMAEFVQVNGLDIESVLENKPVLSKLHLHTKLVKCQLKQGTLACIVIHDLYQGKTWKGMLSRAKMKNLIDAYLTTSMSILEGIIIAAREAAKLPKKGDPDAVILSGGLTKLVKVQSLLNECFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEC9</accession>
    <name>M5GEC9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase catalytic subunit A</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_19851</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632196.1">
        <property type="nucleotide sequence ID" value="XM_040771686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEC9"/>
    <dbReference type="STRING" id="1858805.M5GEC9"/>
    <dbReference type="GeneID" id="63686748"/>
    <dbReference type="HOGENOM" id="CLU_008162_3_1_1"/>
    <dbReference type="OMA" id="RIVKTFW"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055082">
        <property type="term" value="P:intracellular chemical homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000052">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005725">
        <property type="entry name" value="ATPase_V1-cplx_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003220">
        <property type="entry name" value="PRK04192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01042">
        <property type="entry name" value="V-ATPase_V1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="28"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="ATPsynthase alpha/beta subunit barrel-sandwich" evidence="16">
        <location>
            <begin position="131"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="14">
        <location>
            <begin position="236"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="17">
        <location>
            <begin position="470"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU05302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="618" mass="68124" checksum="1E8B30E596534B99" modified="2013-05-29" version="1">MAGAMQNAKKTLPKIADEDRESRYGQVFGVSGPVVIAENMTGSAMYELVRVGHDELVGEVIRIDADKATIQVYEETSGVTVGDPVLRTGKPLSVELGPGLMENIVDGIQRPLRSIQQLSRSIYIPRGINTTALDRSLKWDFTPDSLRVGDHITGGDIFGTVYENSLISKHKIMLHPRAMGTITHIAEKGSYAVDDVVLETEFEGKKSSHTLMQIWPVRAPRPVTDKLTANYPFLTGQRVLDALFPSVQGGTTAIPGAFGAGKTVISQAVSKFSNSDVIIYVGCGERGNEMAEVLADFPELTMTTADGRKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYWRDQGSNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGTKLASFYERAGKVTCLGSPERTGSVSIVGAVSPPGGDFSDPVTAATLSIVQVFWGLDKKLAQRKHFPSVNWNLSYSKYIKVLEPHYEQTYPGFVELRTRAKEILQKEEDLAEIVQLVGKAALGEPDKITLDVARMIKDDFLQQNGMSEYDAFCPFYKTTGMLRNFVAFYDQALKAVTNSDITFAKVRDNASDIMFRLSQMKFESPSQGEEPIKKKYDALYNDIQDKFRQIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ1</accession>
    <name>M5GEQ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632491.1">
        <property type="nucleotide sequence ID" value="XM_040777516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ1"/>
    <dbReference type="GeneID" id="63692578"/>
    <dbReference type="HOGENOM" id="CLU_548621_0_0_1"/>
    <dbReference type="OrthoDB" id="3051796at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="98"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="57071" checksum="51916EA29A78A08F" modified="2013-05-29" version="1">MTTTVDVHVATTTTVFTKASYTPRQVSAPTQGMIGLLHQQRDRDQPRQQPLMQSYKHIPRPGHVRQIVANWPPRPTRRASAAVVVPAQPSQSTQGPIYKLPREILEAIFDHYMVAWEWKIHADIHTVSPMFNELARTLRNISRVCKLWRYICHDSPRLWRNILHCSLEVELRHTHSYKMSMDRCRNVPMDMWISGYSELVEVYELLREKDAFNRVRSLHVGHAQIATRPDKDIVPWFIHCKLENVKRFSLDYADISMCEFAEYLRQFPKLEYLRLLHDRFSDYIDLTDADAQETRVAIPNVKCIELIQEKRDWISQVMHRLVTTNLTCMSITLSSRKGPGNTASITLADAPWMCISLRRIALGNHLDYADIIGIIQPLLALSHLHLFRSAVWGAQEEETKQPCDALLAMLHARPPGAVDGGTTLIPALRVLSFYAYPLSTGALHDLVSNRKQSHSVPLKLVGLDPDWVKATNEEDLARITGLVDVYRTTAYHLLEWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEX4</accession>
    <name>M5GEX4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_104267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632671.1">
        <property type="nucleotide sequence ID" value="XM_040767898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEX4"/>
    <dbReference type="STRING" id="1858805.M5GEX4"/>
    <dbReference type="GeneID" id="63682960"/>
    <dbReference type="HOGENOM" id="CLU_063723_1_0_1"/>
    <dbReference type="OMA" id="HGENQTW"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067707" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="2">
        <location>
            <begin position="27"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="34323" checksum="D478457028A934C2" modified="2013-05-29" version="1">MFPLLSLALSASVVVAAPAAIPKLGSIIYDGRVPWSYTPYSFDANSSIYQNTDNVHGVNQTWDQIIKLPIVTPSMFDLPNTVFPHGTRSVEVTINDNSIFQPGGAGPDYGFRRSELVPAPNNGTDATVQGTTTFHWSVRTDPTRPLNYTGHEYHPTWHETHDYSTSEFTFHTGTYFNQSNEIPYYPGLDLTTPKTLRLAGRQTSPEFVYISVPFTEDTWHNFAVTLGWNSNEMTIYYSTDSEPLKLVAGPVTNNNTGGGQFHMGVFKLPTPPSADVATEGYQESNINEGLIYGGCFIEDSSMGGVRLSPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF48</accession>
    <name>M5GF48_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_102927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632861.1">
        <property type="nucleotide sequence ID" value="XM_040767688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF48"/>
    <dbReference type="STRING" id="1858805.M5GF48"/>
    <dbReference type="GeneID" id="63682750"/>
    <dbReference type="HOGENOM" id="CLU_012596_1_0_1"/>
    <dbReference type="OMA" id="PDGLGCY"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF160">
        <property type="entry name" value="NODULIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="602" mass="64810" checksum="0625EFB833661C57" modified="2013-05-29" version="1">MSEPFEKSSRRWASFVGSVLSAVGAGTNYAYSAYAPQLGNRLHLSSTTLNIIGAAGNLGVYLSGPFWGYIVDKRGPSLPLLLASLFLLLGYLGIRLAYDGVLVLHGGWELGMLALFGFCTGGGGNAGLTSAVNATAKSFHDKTRASATAIVLSGFGLSAFVFSTLAATLFPGETSAFLLTLALGTSTSMLIGYFTVKPVPPHHQALEEPPYAREHVHERGHEEQGFEPMVSDGEEASEEQLEELSDVYDLEEPTSATSASALLERTEGRSASFELSPTRSMSPVGETHRRLLHPPRPGMGRGSRSRSSRRDAVQGSVDLKPAEMALDVDIHGRELLLNMDFWMLFIILSCLSGTGLMWINNVGSVAQALWRYNHPDDPDGYSKLQAAQVSIVSIFNCLGRILIGVSSDVSQHHLGAKRSYLLSFVALSFIVSQLVAARISYATHLWVASMLLGLSYGSVFGIMPMVSLEWFGMGHFSQNWGFLALSPLFGGNLFNLFFGRNYDSHSRPVAVGATPDHSTLASVSPTGSTAASLMHLAARAGGVSDPHKQCFDGRLCYVDSLTLTTVACCLAFVLSFWAAWRDMRRSVRRGEGWVSIGEGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF80</accession>
    <name>M5GF80_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Squalene monooxygenase</fullName>
            <ecNumber evidence="4 10">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_65031</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="4 10"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630822.1">
        <property type="nucleotide sequence ID" value="XM_040775768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF80"/>
    <dbReference type="STRING" id="1858805.M5GF80"/>
    <dbReference type="GeneID" id="63690830"/>
    <dbReference type="HOGENOM" id="CLU_026390_0_0_1"/>
    <dbReference type="OMA" id="AKRTFYW"/>
    <dbReference type="OrthoDB" id="1678617at2759"/>
    <dbReference type="UniPathway" id="UPA00767">
        <property type="reaction ID" value="UER00752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Squalene epoxidase" evidence="11">
        <location>
            <begin position="166"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="497" mass="53494" checksum="C7F6A749D7762608" modified="2013-05-29" version="1">MASPAPTQLHTDILIIGGGPAGLTLARSIQHFSQNPRSILILERDLAPQGPDRIVGELLQPGGVNALRALGLQGALEGIHAVPAKGYCIVNTAQDAQVSVPYPEGEQGRSFHHGAFVAALRREVATTPGVTLQEATVHSLLEDPQTGRVIGVTATPKNGDPTPFPADLVIVADGHASKFRHILLRSPAPITRSHFVGLVLHGARLPVEEHGTVVLIPGQGPVLMYGLAPGDTRILIDVRGKLPSSSTGALQAHIRTHVLPHLPQACQAPLESALQTQRLRSMPNSYLPPSLQATQQHKQGVLLVGDAFNMRHPLTGGGMTVAFSDTLLLGKLLAPCFPSDWASVARALHRFHLQRKPLASTINILSLALYDLFGASSPELATLRQACFDYFLLGGECIRGPVGLLSGLEPRPALLFYHFFAVALYAVWRVLTRPASPISESGDTPLYTSGHAHLTLASVGRVWEMFRLLWVACVVFLPLMWVEMQDLTRAWWGGLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF91</accession>
    <name>M5GF91_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_19380</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632956.1">
        <property type="nucleotide sequence ID" value="XM_040771482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF91"/>
    <dbReference type="STRING" id="1858805.M5GF91"/>
    <dbReference type="GeneID" id="63686544"/>
    <dbReference type="HOGENOM" id="CLU_000315_2_1_1"/>
    <dbReference type="OMA" id="LLRYPFC"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="93"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="433"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="518"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU06062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="685" mass="79116" checksum="03BA05ED8804182D" modified="2013-05-29" version="1">MKLEGVARRELPEDRYLRRREENILKRRSGRRRLTQAERNSISLKLHHPELRDCWGDLASSIPIIVPERAPQPKSLKVTLLPFQQESLYWMRKQEESVWKGGMLADEMGMGKTIQTIALLVHDRRKPNLVVAPTVAIMQWRNEIEANTEDFKVCIWHGSSRSNDVKELQKYDVVLTTYAVLESCYRKQQTGFKRQGKILREPSALHQIHWKRVILDEAHNIKERATNTAKGAFELNSDYKWCLSGTPLQNRVGELYSLVRFLGGEPFSHYFCMRCDCKSLHWQFTDRRTCDQCGHSPMNHTCFWNNEILSPIQKYGMVGVGRVAFKKLKILLDRMMLRRTKLERADDLGLPPRTVTVRRDYFSPEEKELYQSLFTDAKRQFSTYVDQGTLLNNYSNIFSLITRMRQMACHPDLVLKSKTNKALSSDIVEATVCRLCNDIAEDAIKSRCNHIFDRECIKQYLNTSVEHQPHCPVCHLPLSIDLEAPALEDQAEINSKARQGILGRLNVDEWRSSSKIEALVEELSNLRKQDATTKSIVFSQFVNFLDLINFRLQRAGFTVCRLEGTMSPQARDATIKHFMNNVNVTVFLVSLKAGGVALNLTEASRVYLMDSWWNPAVEYQAMDRIHRLGQHRPVQAIKLVIEDSIESRIVQLQEKKSAMVDATLQRDESAMGRLTPEDLGFLFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFH0</accession>
    <name>M5GFH0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633176.1">
        <property type="nucleotide sequence ID" value="XM_040771543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFH0"/>
    <dbReference type="GeneID" id="63686605"/>
    <dbReference type="HOGENOM" id="CLU_1219659_0_0_1"/>
    <dbReference type="OrthoDB" id="10483598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="50"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="227" mass="25817" checksum="8D9F5F728CFC1CDA" modified="2013-05-29" version="1">MMTYASPLANNFHSIYEMACWIFWMQAARRNKLNRHAVGPNFLHFMISHDDPTHLTFTLLGNALVYKTSTKGTTTSITRKVDGKSTGLAKIYWSEVEGGETMIQFGGHPAIRVEQFLPPVQDIGLEHQFTVNGRDFHCAFTSDRFVLTDSNDALLGHDTRTPHGPTHRLTPDCFEVSIDLFDAMDFVFVAYICMECARRDGRASILPRPYSQEWQTLQRSMPTVHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFP4</accession>
    <name>M5GFP4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Outer arm dynein light chain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_48540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631187.1">
        <property type="nucleotide sequence ID" value="XM_040774844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFP4"/>
    <dbReference type="STRING" id="1858805.M5GFP4"/>
    <dbReference type="GeneID" id="63689906"/>
    <dbReference type="HOGENOM" id="CLU_009538_1_0_1"/>
    <dbReference type="OMA" id="NTPYMPL"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="450" mass="50121" checksum="E17D32E71F9A9D75" modified="2013-05-29" version="1" fragment="single">MANTEQGDDYIRRFAAFIRSHEQSLASAGFVPRTRHHSTSQSEPYNLLSWVTPSQPQRHTSPVVLSIDPHHLSYILMRMEALGLNVGDMDVKLETPLKQNAYMSLLAAKDRDAQSIFSIRSTLSAVSKLSLGPSLGWLMGGAVQPPSLDTELKHMYSLMTLLPALSLHAFSARMITELAEDPPVDNALPLDVFKSLQSLEMTDVDPRDYIGWDQLSIGLRSFTIRRSSVEDVSDVLVDAVANDMVRRKGDLKTPVKNRPRLIHHASSIRSQHPSISPDGLPHSPPAEAPPPTLPAYTWASLRHLALPDNALTFFPSAPTPYLSALQSLDLSSNLLVSLPPCLSQIPTLTHLSVAHNMLDSILGIGALLPEVRSLNLSHNRLDSLCGLERLPRLRFADLRSNALEDSAEVGRLSQCMEIEDVWIEDNMFCRTEPDWRVRVFELFRREGREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFR2</accession>
    <name>M5GFR2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">F1F0 ATP synthase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_20910</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631242.1">
        <property type="nucleotide sequence ID" value="XM_040772138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFR2"/>
    <dbReference type="STRING" id="1858805.M5GFR2"/>
    <dbReference type="GeneID" id="63687200"/>
    <dbReference type="HOGENOM" id="CLU_085752_0_1_1"/>
    <dbReference type="OMA" id="TSPYMWG"/>
    <dbReference type="OrthoDB" id="10264021at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU04348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="208" mass="22078" checksum="FB208E033A07BF90" modified="2013-05-29" version="1">MGVVTYTSYLAVFIIVLITLYLLFAGQGEWFNIGHFLEESSPYMWSMVGVGLCIGLSVLGAGWGIFITGASILGGGVRTPRIRTKNLISIIFCEVVAIYGVIMAIIFSSKFAYIPESDLRTPSNYYTGFALFWGGLTVGVCNLLCGISVGITGSNAALADAADPTLFVKILIVEVFGSIMGLFGLIVGLLMASKANSFTAMEKAAVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFW2</accession>
    <name>M5GFW2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_14545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631387.1">
        <property type="nucleotide sequence ID" value="XM_040771040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFW2"/>
    <dbReference type="STRING" id="1858805.M5GFW2"/>
    <dbReference type="GeneID" id="63686102"/>
    <dbReference type="HOGENOM" id="CLU_031807_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="476" mass="53142" checksum="4B831D26D7B9556F" modified="2013-05-29" version="1">MEALSRGRNHMLSTSCIEEMVTASLASDSSPVILQLLECSEELNADSEVFDLPYFILTLLDGTSFVTKVVLHTTVVPRLHNQEIEVYDMITLTSYERLMGPRNCWISIPLAFPHWSNIVSDWQAYHHSLGYATALYEFHYVWPQVPQSAPPPLTMQVTMIGRGVVPPDLITPMLPVVPPPPVPVPTQVDHLLLIDASLDCIALCYYAWHPTHVPGIMAQPAPLPVVPPALGTALFIGPIQTCSLNVTIRITRLWSKDKGTIDILYHDLTGEINLVVCCAVHAKFADVEVGKVYTIFNLNAIAAVQEYCHLFHRSQLNFHQQQSDITEVPDNGTILEYHFNICQIVQIPELPDKKCIDMPCIIANTSNIMHGKAPRHASYAHQKQGYAAGAWKDGKLALLKNVCINKHHGLSLKTVSDYMKIVWNPASILGYTSMVTWWDFAKEDPTVAPLECCLQCRRRSLSCNLPTDHSSLSSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG55</accession>
    <name>M5GG55_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_14030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631792.1">
        <property type="nucleotide sequence ID" value="XM_040771013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG55"/>
    <dbReference type="STRING" id="1858805.M5GG55"/>
    <dbReference type="GeneID" id="63686075"/>
    <dbReference type="HOGENOM" id="CLU_070940_1_0_1"/>
    <dbReference type="OMA" id="NWEDERD"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="24739" checksum="EF118C0D50A95B50" modified="2013-05-29" version="1">MTEDELDKLLKQEESAFSKELEVERILKAFKLNPYDILDIDYTATAGDIKKRYRQLSLFIHPDKTPHPRAPDAFDLLKKAESDLSNGEKREELDAVISAARVQVLKQHSLPTSITDFDDERIKEKGLKFRDLVRAKSKELLVEEELRRRRAVKMNLANEGLEAKKKEEEIATKKRKADDDVKWEQNREHRVDSWRAFQQGPKKKKKKTNVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG68</accession>
    <name>M5GG68_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631857.1">
        <property type="nucleotide sequence ID" value="XM_040771973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG68"/>
    <dbReference type="GeneID" id="63687035"/>
    <dbReference type="HOGENOM" id="CLU_2527403_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="9263" checksum="BDC25D18A55A1D25" modified="2013-05-29" version="1">MLVSPCQQPKKRPVNGSTKLDTHFSSFIPRYMQLLFPWIYAISSRADVGCVTQLLENLTTCHRCADIPALAYIPALCGSFSSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD8</accession>
    <name>M5GGD8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_19858</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632207.1">
        <property type="nucleotide sequence ID" value="XM_040771690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD8"/>
    <dbReference type="STRING" id="1858805.M5GGD8"/>
    <dbReference type="GeneID" id="63686752"/>
    <dbReference type="HOGENOM" id="CLU_041217_10_2_1"/>
    <dbReference type="OMA" id="PVSNDGC"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000229">
        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="215" mass="23967" checksum="7F7737EAC003D384" modified="2013-05-29" version="1">MATPTPTSGSFSALPLKRTKIVLLGDQSVGKTSLITRFMYDTFDQTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIVVFDITNRASFLSTTKWIDDVRSERGGDVIIVLVGNKADLSNDRQVTQEEAQQKSTELDIIYMETSAKAGHNVKTLFKKIAMLLPGNEKEGEQAKEGNQKIDVTSPAKNETPQASNCACW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGE7</accession>
    <name>M5GGE7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="8">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_86455</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="8"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632252.1">
        <property type="nucleotide sequence ID" value="XM_040776774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGE7"/>
    <dbReference type="STRING" id="1858805.M5GGE7"/>
    <dbReference type="GeneID" id="63691836"/>
    <dbReference type="HOGENOM" id="CLU_002173_0_0_1"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08382">
        <property type="entry name" value="C2_Smurf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000017">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000079">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
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        <property type="entry name" value="C2_domain_sf"/>
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    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
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    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 8 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="14">
        <location>
            <begin position="530"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="146"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="263"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="146"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9 10">
        <location>
            <position position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001569-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="863" mass="97142" checksum="189B228F84B41248" modified="2013-05-29" version="1">MADSGQRLHVPGQSRKLRLNVVAASGLIKREVFNLPDPFAVISVDGQAVHNTSVFRKSLNPYWNESFDLDVKENSTLSVQIFDERKFKKRDQGFLGLVMIRLDEVFDWQSGHQEMLTLELKPSNQNMPVMGRLVIYLTADTSTRISNPGPSQLSGNISQLSAPSTSHSNPVNLPVSNTSPALSPRQSFVSGTAGAVESLSPGLNTSSERPDSRASSGLTNISNMTNRMQRMSVNPAQEQIAPQAASPYAPNVAPAPVAQMVNSGSAVPANPNPAHRSGPTQGAQTEDELGPLPPGWERREVNGRSYYVDHSTRTTQWRRPPPVANAQPMEQGADLARSRTRHEGRSLADDMLGTVSGAVTPAHSANAIGAQTRTGVAGVTDPSLGSLPQGWEQRFTAEGRPYYVDHNNRTTSWQDPRRPVFRPQGTPAETVGASSSSSQLGPLPSGWEMRLTASNRIYFVDHNTKTTTWDDPRLPSSVDKDTPKYKVDFRRKLIYFRSQPAMRPLPGNCQVRVRRNNLFEDSYSEIMRQTPEDLKRRLMIKFEGEDGLDYGGVSREFFFLLSHEMFNPIYCLFEYSAHDNYTLQINPASGINPEHLNYFRFIGRTVGLAVFHRRFMDAYFIVSFYKMVLGKKVTLADLESVDAELFRGLTWMLENDITDIIDETFTKSEERFGELVTVELKPGGADVEVTEVNKKEYVDLVVEYRISKRVKEQFDAFMSGYLDLIPQDLIRTFDERELELLIGGMSEIDVDDWCKFTDYRGYQMNDEVIQWFWKCVRSFQPERKSRLLQFVTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPESLPKSHTCFNRIDLPPYKDYESLERKLIFAIEEADTFGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGL6</accession>
    <name>M5GGL6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_98327</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632597.1">
        <property type="nucleotide sequence ID" value="XM_040777522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGL6"/>
    <dbReference type="STRING" id="1858805.M5GGL6"/>
    <dbReference type="GeneID" id="63692584"/>
    <dbReference type="HOGENOM" id="CLU_031900_8_1_1"/>
    <dbReference type="OMA" id="KEREVWD"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16859">
        <property type="entry name" value="ING_ING4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059153">
        <property type="entry name" value="NSD_PHD-1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23011">
        <property type="entry name" value="PHD-1st_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Inhibitor of growth protein N-terminal histone-binding" evidence="12">
        <location>
            <begin position="72"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="11">
        <location>
            <begin position="387"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="323"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
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            <position position="402"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU05703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="49742" checksum="D31942C8CFACC040" modified="2013-05-29" version="1">MPLRPRKKRRSNTSRAVAIIDEVEDIEDVEQEEVAEEVNDVVEHPEVTGQEEADGAEEEGPTEEQIEEWEAFRQEYYEIINELPVSLHRSYNLMQELDEQVEAHLALQLPAIKQYIAFRHALLEPPPAPPPLPDATTSPDVPPESSNSVHLVEKPVSSSGASTTTIDHTVQLVQSPHVNGITESPKSKKRKRSSKDEGSPSRRSPRGASESTTLSRVSSRSSQSSLDPITPDSKNLNGIVTSEVTISKGTQSQAQSKEIEVEAASVITRRMLAQIAQLSRESLRASDEKIGIAKAMYDLVDRHVRSLDAKIKEYEASVAIGLRPGTHPMDGTLTFEEPEEKPEYSDTRRGRKRDRKGKERTDENEAEQPQPSDVVINMPINAMEPTYCYCHRVSFGEMIGCDAEDCPHGGWFHLECLGLDNPPKGSFFCDDCAKERNNPKKKRGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGS8</accession>
    <name>M5GGS8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_102970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767697.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63682759"/>
    <dbReference type="HOGENOM" id="CLU_778494_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="356" mass="38795" checksum="35AA43DAABE20E90" modified="2013-05-29" version="1">MSAHTRLIDAFSTSSTPLRNCTSAVTVDSCGSDMQSHDVPRTLTRVHTVHSPPVHVHLGPPDSEALHEARSNIEVHGRRDDQRTPEYPALHIVTDISTSVTSRAPTTLRRCSKLGRPVLGVRFVCSHMVVWCRWQQAAQGTVLAIMAPPTVVQSPTPRNNVFIDNIIRLENISDWSGFSVVKKAPVPMRDTGSSYIPVEFSYQGKTASNFTVTAVVQYGGTNADGKPYVIVGIDERIIGNVINGSRFKRPDFGGHVTGGHAVFRMDIGNGWDSFVWKGANGKPDKSSSAPDFFRNGGTFRAVMKGWAKESPSKHSFAPGLTQILFVKKSTTVLPTYVGSSGPSIETFIEDFESLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGZ7</accession>
    <name>M5GGZ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 2A phosphatase activator TIP41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_92392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633252.1">
        <property type="nucleotide sequence ID" value="XM_040777068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGZ7"/>
    <dbReference type="STRING" id="1858805.M5GGZ7"/>
    <dbReference type="GeneID" id="63692130"/>
    <dbReference type="HOGENOM" id="CLU_039187_1_0_1"/>
    <dbReference type="OMA" id="DMILFED"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="307" mass="34393" checksum="49068B703AFDA288" modified="2013-05-29" version="1">MTTTSPEIPSHHVDETGVNKSITIHGWKITTTSTSISNASELDSLQRELDLTLPEMTFGHNSVVLSHEASGWTYTFDTKGALKQVCNKELGPGDGGVKVGHAEAWASTRTVPNSLTPVSEMTVAKPYDWTYTTMYAGHASTSTPQWLPADPEDSSQSIPMATLTKPDPILYYAATQLFEDELHDNGASMYIIRVRVMPTCFFLLGRFSLRVDHVLFRQHDTRLFHDFSSNMLIRETAGWEAPYETIRARLPNPDDRTRLTDTQWVASIFNELPTRITQNKRSGGGTGWRGLTRRVETILLGRDTQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH11</accession>
    <name>M5GH11_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633322.1">
        <property type="nucleotide sequence ID" value="XM_040771577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH11"/>
    <dbReference type="STRING" id="1858805.M5GH11"/>
    <dbReference type="GeneID" id="63686639"/>
    <dbReference type="HOGENOM" id="CLU_083061_0_0_1"/>
    <dbReference type="OMA" id="HSTAYER"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="154"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="30171" checksum="51EE537A4EAD096D" modified="2013-05-29" version="1">MDKYLYRTKPGGARGAFNSNIGEKRQALRFNPFAPPIGAKTDKERRREAAQGKARADKLLAPVRATVESRSKPDKHAIIDVGPPPGPLQKALRNQILNSLSSESNPITHSTAYERCEPTSSAATGHQRSDGRRSQLYFKSRNIKLREQAKERGHENEVFHGCVVYINGYMNGTTDLEVKRIVGLGGGRVRYMAGGGTTHIITSMPLSASKTHTHLNTNERKVHVVTPEWILDSVKMKKRQPEWKYKIVESKVQGSLGFGVKDNTVIDLTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN58</accession>
    <name>M5FN58_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAD-superfamily phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623768.1">
        <property type="nucleotide sequence ID" value="XM_040774122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN58"/>
    <dbReference type="STRING" id="1858805.M5FN58"/>
    <dbReference type="GeneID" id="63689184"/>
    <dbReference type="HOGENOM" id="CLU_056221_1_0_1"/>
    <dbReference type="OMA" id="MLMANMM"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26999" checksum="F91231FDA87FFCCE" modified="2013-05-29" version="1">MPIIRHVFTALRIITKPSVLVPNLAVKSVANINFANLREAGYEGVVIDRDNCLTKPRQDVLVPSLKDAWSSCLESFPPSRVLIVSNSAGTSKDASFLQAEALTRNLGVPVMLHEAPKPWVKRPPTPSAEGVSTDTKPVQPRKVPTPRLVVIGDRLSTDIVLGARLPKSFSIWTTQVWEEESAGVRIVRLVEGSVLSAVKGWRGWRRKRRGLEPEGEPKEFVIDVPVAPQPEKKSMVEFCPISSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNE2</accession>
    <name>M5FNE2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_91618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624188.1">
        <property type="nucleotide sequence ID" value="XM_040777011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNE2"/>
    <dbReference type="STRING" id="1858805.M5FNE2"/>
    <dbReference type="GeneID" id="63692073"/>
    <dbReference type="HOGENOM" id="CLU_080483_0_1_1"/>
    <dbReference type="OMA" id="MASAWIQ"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="2">
        <location>
            <begin position="67"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="27908" checksum="86A41233395BB993" modified="2013-05-29" version="1">MDSENKEGVYAVRHSQKPVNDFRQSESSTEVSPINRNPLAVTFIMLFPYREGDPEDDQPRKVSFMEHARWMLQYHDRHFRKNNTWIFVAFGIIQKHEAMASAWIQIRHTDFQKASNLLSTVTIEWLQSATEEEESTGRTSNPAINTLAGCVMGSDSSCIALRSQIWGTAVYLAPPNLWFTITPNDLHNPLAQVFTGKDINMNCFLSTIGLNTSKRAQIIAQDPYAAAKFFQYIISSMMQCLFCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNW4</accession>
    <name>M5FNW4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_84391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT98000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624898.1">
        <property type="nucleotide sequence ID" value="XM_040776679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNW4"/>
    <dbReference type="GeneID" id="63691741"/>
    <dbReference type="HOGENOM" id="CLU_004965_1_1_1"/>
    <dbReference type="OMA" id="ACSFLWY"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="678"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="744" mass="83620" checksum="2B378E51B01C732F" modified="2013-05-29" version="1">MTKERSHDKLEDGSSSVERVVVEVDNDQEEDSPYPEVRAAVSNTDDPSMPVNTFRMWFLGVLFTIVISGLNQFFGFRYPSVTITSLVAQLVALPLGKLLEKILPTRQFNTFGYRWSFNPGPFNIKEHTLITVMANVCSGGAYATDILAVQKSFYNQQLDPGYELLLVISTQLIGFSIAGLCRRFLVWPAAMIWPYTLVYSALFNALHTSYGKSDDGWMSRNKFFVIAFTCSALWYFFPGYIFTALSVFNWVCWIAPNNFVVNSLFGYQTGLGMGFVTFDWAQIAYTGSPLVTPWWAQANVFACLAIIYWIIAPIMYYKNVFFAQYLPMSSSGSYDNTGAPYNATAIIVDGIFNPEQYANYSPLYLSMTFALAYGLSFGALTSTIVHVFLWYRHDIVRQFRASLKDEPDIHARLMLAYPEVPNSWYLGLGLVSFALAIVTIEVWHTQLPVWALILALLISLFYLIPIGMIQAVTNQQVGLNVITELIVGYALPGKPVAMMIFKTFGYITMAQALSFVGDLKLGHYMKVPPRMMWLSQVIAALIACFVVVGVQNWMFGNIVGMCTPEQADNFTCPGIDVFGTASLIWGGIGPTRIFSHGLYQPLLWFFLIGALLPIPFYYLAKKYPMSGWKYVNIPVFFTGTGLMPPATGINFSSWFMVGITFMYFVRRYHFGWWSRYNYVLSAAMDSGVAITTIVIFFCLYFPNGGVSLDWWGNSVYANTLDGMGATYLTLNPGEVFGYQPGTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP51</accession>
    <name>M5FP51_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High affinity sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_85532</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">High affinity uptake of sulfate into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623716.1">
        <property type="nucleotide sequence ID" value="XM_040776741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP51"/>
    <dbReference type="STRING" id="1858805.M5FP51"/>
    <dbReference type="GeneID" id="63691803"/>
    <dbReference type="HOGENOM" id="CLU_003182_8_0_1"/>
    <dbReference type="OMA" id="ISWGIVH"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902434">
        <property type="term" value="P:sulfate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000046">
        <property type="entry name" value="Solute carrier family 26 (Sodium-independent sulfate anion transporter), member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="10">
        <location>
            <begin position="548"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="692"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT96818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="784" mass="85309" checksum="72F6BA1A4632B0C3" modified="2013-05-29" version="1">MGFVESLKKAGKKVIGYPERPVPVVSSMDFVRGLSKNPKQDAINYLRNLFPFLQWITRYNLGWLTGDVIAGITVGLVLVPQGMSYAQIATLPVQYGLYSSFVGVFVYCFFATSKDVSIGPVAVMSLETATIISHVQAAYGNRWSNNEIATTLAFMSGFIVLGIGLLRLGWLVEFIPAPAVSGFMTGSALNIAAGQLPQLFGVQNYFDTRAATYQVVINTLKYLHLSTLDAAWGVPALAFLYFTRWLLKHLAERHPRVRRAAFFMTNLRNGFVVIILTLAAWLYCRTRLSKSGKYPISILLTVPRGFQNVGQPHIDPALLSALGSELPVATIILLLEHIAIAKSFGRVNGYKINPNQELIAIGVTNTVGSCFNAYPSTGSFSRSALKAKSGVRTPAAGWFTGIVVIVALYGLTDAFFWIPKAALSAVIIHAVMDLVANPQQVFQFWRVSPLEFFIWAAAVLVTVFSSIENGIYTAIAASAALLLVRIARPRGHFLGRVTVRADPFATPEASIANGKESSAPGIVREVWVPIDRESHIMNPTLKVEPPPPGIIIFRFEESFTYPNSSRINSIIVDHAKETTRRGLDQANIRLADRPWNDPGPRRGEPDPAVLDAKKPLLKAVVLDFSAVSQIDTTAVQSLVDLRRELEHWVDAPVEFHFAGILSPWIRRALIAGGFGTGTPGRSLPIEIAPVVPPSDDRAWGPGDEFPARQGGHREDLEALATDADSGLEKDPNALAGASTTDFEAPIVSTMTPFFHFDLSTAVRSVQGHSLPEPPEVIGEGASAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPC1</accession>
    <name>M5FPC1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625323.1">
        <property type="nucleotide sequence ID" value="XM_040769137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPC1"/>
    <dbReference type="GeneID" id="63684199"/>
    <dbReference type="HOGENOM" id="CLU_704030_0_0_1"/>
    <dbReference type="OrthoDB" id="2746474at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="392" mass="44867" checksum="4DE95A1001E37928" modified="2013-05-29" version="1">MKMGNGSLPELPPELYEHIIAFLDDRRDLLRICLTNSILHDLAARYLYRRLRIQDFRRAVAACILLVKRPHIAAYVTQLEADFGEVPDWIVHQWPKPRIFLNTFAPAYCRIMFRAFGSMNQLEHLTFKNTSPLGRLPMTNLANCTFRVRSLTLPTSTFEHVILQSQPLIEDLEVLDGPSFSILALRRTAIPHLKRLAAFQIDAKYLIPGRPVVEFRRLDTLLEEHVPDCLNTLSQSTGPLKRVRLLMMKIDGLFFVRAAAAIPDIVDLVIHGMGNVEHTVSEELQTFEVVHAFRGFRSLKNIEIHSYYDGSAEYYFPPIHVLGRACSTLETFTIVDELRGNSDRSRLPAYQLHRELGKILQEGELEWIPRNGIVRTPPSVPGRQVTLVEWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPI1</accession>
    <name>M5FPI1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_101687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625483.1">
        <property type="nucleotide sequence ID" value="XM_040767576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPI1"/>
    <dbReference type="GeneID" id="63682638"/>
    <dbReference type="HOGENOM" id="CLU_296823_0_0_1"/>
    <dbReference type="OrthoDB" id="3033638at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1016" mass="114436" checksum="49A899766AF85DC6" modified="2013-05-29" version="1">MCGSWSPRRHSQCVAPGERMGAYGGTQGVPAPDPLASPSRLGSVLSRFSRNPAPSAPRRPASPPALISGAPATPLRLHSSPYVPRGGRPAAAGPAPRPMSSRMANSVNSGTKITSAQHMEWILTGGILGRDTSWTQAPLTHSPGVEQVFRPRPGDLRATPVAMRKPFEQPVMSSKKRWFPPIPDDDLKINGNIPNPNPGEFFIDVPEIEKEGIYALPYVRFKELQSDLDVTIQRPTTYGMVVGFPSLYRRGGHQYVPDDWNFPTFPVQQRPIEAPDNETDHWAQYDMLDTSTPVMTGCWRDGMDGTGMNVHQWKSIWKPESRKYSFMREYARQMLDFVTYLDRVLNARMTMTFLMPCHVGPTKQPPVMSIISRIAWADGPLMETFRRIEDIVNTRMATRIHDLLTNHTQTFQCRDPEYGITEEQATFIAEPLDLADPVTLDGPPRYWLYSAIPTTNLPAVPERLTAMVRHYFRTYDPAHLDCVEEASFEINQIWCFCRPSHWRGFIDDILSGREPTIDHSGGHIRPTTNRTGLTNLMAILCLMQVEEWERTGRVTEPWIPEQYEDNRPETRPTNTWPPPASQFHPQSGGHERRVSHASSSHGSAGHGQAAGPSRPTAHAPQAQAPSSYRPVSPNDMVQTPARPTRQLGTHGWQRSGEGVPFSPPHTPRRIEARPGIDNSAGVSSCSMPDQPSTSIWPDRERRRQENRIRHKHVKRRARDLSDMLDASIWKAAQEVGILSAAMCSEILGHQNIVRFRKQRAVNLKNVAVHLMRQEFWERGQHFDIQKDADAWKSRLDVLRADPGEEAVGCQLLEQHRSVHTNQVRITRKAREVDTTHTTLAIQNEVEAFYTRTGGHIVGFAIRGDRNDHALPQFFGNTVGESFFRQVFWKPVQEVAEDFDVYANLGVQGTIMGNNTVTMQYARFRSTVEDAFHVTLEGWPLRSFVNPSLLGVADLRVLKAALAEGRCHFRRLTLEELATRCIMTGFAFSPLFSGILTFILQPSEAVVMEGFRKEVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPN8</accession>
    <name>M5FPN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_102577</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ARPC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624096.1">
        <property type="nucleotide sequence ID" value="XM_040767643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPN8"/>
    <dbReference type="STRING" id="1858805.M5FPN8"/>
    <dbReference type="GeneID" id="63682705"/>
    <dbReference type="HOGENOM" id="CLU_101888_2_0_1"/>
    <dbReference type="OMA" id="GMGCIMR"/>
    <dbReference type="OrthoDB" id="429520at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.190:FF:000003">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17022" checksum="D2535E2524840C56" modified="2013-05-29" version="1">MDTHFRRINIDQYDEDVLLPSELYDPDPRSPAQVQADAQQRSSSVQGSLSRGDVAGALVTVLDRPAYGEGVDEAKAQTLSTLLLILNSTKTSDIPTLVRALSEEQQDTLMKYLYKGMASLGEEVNGSVLLGWHERLTEVAGVGCIVRVMTDRRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPW3</accession>
    <name>M5FPW3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="2" type="ORF">DACRYDRAFT_119470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPW3"/>
    <dbReference type="STRING" id="1858805.M5FPW3"/>
    <dbReference type="HOGENOM" id="CLU_079430_1_0_1"/>
    <dbReference type="OMA" id="AMGAVMK"/>
    <dbReference type="OrthoDB" id="538640at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="20775" checksum="117E17AA0BCCACDE" modified="2013-05-29" version="1">MYRALLPYPSRFAVSRATLPAIRWNFSTALGGAQPLALRAQLQQGLKAAMKAKDSVKATVIRSVIADVVNTDKASKSGEAVGTPEVLRALQQGITRREDAQKQYLQGDRPDLAQATEAEITILRSFVPPQLAESEVDVRIARVLEEMKDRGEKVVMGGVMKRFWEGTGKEEISAQLVSERVKLALAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPY0</accession>
    <name>M5FPY0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_60198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623527.1">
        <property type="nucleotide sequence ID" value="XM_040775619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPY0"/>
    <dbReference type="STRING" id="1858805.M5FPY0"/>
    <dbReference type="GeneID" id="63690681"/>
    <dbReference type="HOGENOM" id="CLU_026014_0_0_1"/>
    <dbReference type="OMA" id="DLGCIFS"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067163" description="Cell wall protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="40930" checksum="5D548EE063137113" modified="2013-05-29" version="1">MHTLSALALGLLSASQLARGLPTKREVPQEHSHQSIITSVQTSLQLNNPNGIVDSVFGLLGNAAAAGGAGNTTDLDCLQQATADQAFTNAKAAGNVQGMVDALIYRALERNTGAVGLASNSCTTLTAVNPEIAAISQHQDPASPNAASTNKAIVLVLAQQIASVGGNPQDALKSGTFAPGQIGDPTAKGNTCDDANDPNGCIFTQNLLVDDATAAEIDAAVAGTSNSNNTSTVSTGGSASNSTTGTGNDGTCNPVGVDVTVTSTAAATAISNSTVASATSISTVSTGSSSSGTSANLQTFTGARNTGASSSAAVVAASTTQAVAAATATAISTVASGTNLQTFTGALGGIAPPPVVAGGKGFVTDNSDFVNLAAALGRSCDVQHNACADQANSQHQTPFSVSDCDQQDTQCKAAGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ11</accession>
    <name>M5FQ11_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625803.1">
        <property type="nucleotide sequence ID" value="XM_040773509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ11"/>
    <dbReference type="GeneID" id="63688571"/>
    <dbReference type="HOGENOM" id="CLU_1749575_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="17184" checksum="AF96CBBB637FC403" modified="2013-05-29" version="1">MVPTNQTLSIISETRGPIDALQEDEGMSRDMQSGADWAQETLSGKPPKSRRPLKIHGSGNTCRLSRYWRMRTKTTHIAASKTPLENMVADFKERSFIQNREKLKREVEVADEKFDEPDIKFQAFRAEAAELPMELEEAQKEYGDFLEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ58</accession>
    <name>M5FQ58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dimethylaniline monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_91449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624436.1">
        <property type="nucleotide sequence ID" value="XM_040777008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ58"/>
    <dbReference type="STRING" id="1858805.M5FQ58"/>
    <dbReference type="GeneID" id="63692070"/>
    <dbReference type="HOGENOM" id="CLU_015676_1_0_1"/>
    <dbReference type="OMA" id="LWFMMGN"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="605" mass="67089" checksum="6E6AF494BB0A1C3E" modified="2013-05-29" version="1">MAKDLPTHSTLGGPPPPSVDAGQAWFTSFSNVISSCDVPALLGLIREDGFWRDMVALTWDFRTFKGTDRIKEFLHDRLQGAELSSLKLSNDFPPKLEQPWEDVTWLIVTFTFSTKVGTGTGIARLVYDHKPGAWQAYTIYTTLSGLHGVTEALGSNRLMQPNHGQWLSSLAQTLKFEKDPEVLIIGAGQAGLDVSARLKMMGVSVLCVERNARIGDQWRERYEALCLHDPVWYDHLPYLPFPSAWPVYTPAAKLAQWLEFYAQALELPIWLSSTIESCTWLEGEGKWEVVVLRGKEGGGKERRVMKVGQVVYAVGLAGGVPNMPKIAGMDEFKGKIIHSVQHTTAKDYVGKKVLIIGAATSAHDIAYDFANHDIDVTMFQRDSTHVITTKHGIPILMGGAYWGEDSPSTEQADVLFASMPIEVMRLAHARLTRQIAELDRELLDGLDRVGFKRNDGVEGSGLMYLYFSKGGGYYLDVGASQMIVDGKIGLKSRGEIDRFTSSGVRFSDGSEIPADLVVFATGYGNIKESMKSMFAPDLIENLKPVWGVDEEGEIKGVWGDSGHPKFWYMLGNLSLCRFYSKHIALQIKAMQMGVFGDRYQKGKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQH5</accession>
    <name>M5FQH5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase Pif1-like 2B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_29761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623887.1">
        <property type="nucleotide sequence ID" value="XM_040774323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQH5"/>
    <dbReference type="STRING" id="1858805.M5FQH5"/>
    <dbReference type="GeneID" id="63689385"/>
    <dbReference type="HOGENOM" id="CLU_001324_4_3_1"/>
    <dbReference type="OMA" id="IISRINM"/>
    <dbReference type="OrthoDB" id="3353471at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23274:SF11">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23274">
        <property type="entry name" value="DNA HELICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="1">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="131" mass="14529" checksum="430055B0C2DC8E70" modified="2013-05-29" version="1" fragment="single">VNTLHHHGVPPHALHLKTGAVCALMRNLSMQKKLVKNAHVVVEALNQCFVQVCILNMDGQLGNELHCIPHIHFTFKPHCASWTVIHNQLPLCLAYATTFNSCQGLTLDRSVLDCCTDVFAHGQLYTALTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQT7</accession>
    <name>M5FQT7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_90443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776952.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5FQT7"/>
    <dbReference type="GeneID" id="63692014"/>
    <dbReference type="HOGENOM" id="CLU_008455_13_5_1"/>
    <dbReference type="OMA" id="PPYNWSQ"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF160">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
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            <end position="353"/>
        </location>
    </feature>
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        <location>
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            <end position="392"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="454"/>
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        </location>
    </feature>
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            <begin position="484"/>
            <end position="502"/>
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    </feature>
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        <location>
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            <begin position="65"/>
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    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="558" mass="62051" checksum="239912F1D38A533D" modified="2013-05-29" version="1">MEYHHHHEEHPRHLARSHAHEGDIPGTVYMKAEEGDDTKGSYGQALFPVPAEDPNDPLQWPNYKKTMILIICSLYSFLGNSALLGPSVYIGIYAEEFGVDPNTASGLISYPNLVYGFGSLILVPLYLKIGRRPVMLISLIFFLVGLIASSQCTTFSGLMASRIIHAFGSGVCEALPVQLVNDIFFLHERGKRIGYYTICLCLGSTGPLYAGYMLTGGFSWRLYFYVEIAFAGALFILAFLFVEETAYKRVSSNPGTFHPSTTVQPAGPSGSTGSFNEPSAEKIIPSAEQIEYATPNIPERKSFLQTLKPWSSIDHEAPFFMTMLRPFTYYLVPAVLWVVTTYGIYIGLGALAFNYTFPLKITAPPYNWSQTNAGLIAVASLIGYLLAAPFTFSSDRVAAYFTRKNDGVREAEMRLSVMLPAMLIAPAGLVVYGLTAEKNLHWIGYFIGVAMDQWGSYFYFSFTLAYAIDSYYANTSEMLIAMNLGKQAISFGMGIYLLNWILEHGYAVMIAGVFMAILLANNLCLLIFMFWGKRIRTWTSKTWLAGMHKATITQVMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR46</accession>
    <name>M5FR46_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="367" mass="40907" checksum="4CD0DA7DFD89FF90" modified="2013-05-29" version="1">MDLDDNIQPVNLDLLPPSLHTGLLSSGGSTWNLQSGTPHYCLPLPSPSMALIPSGRSLVLTGGTSGFHSGQHVSGFQSAASLPHANINMPIALLINFHMLMHKVAAGVQLPTTKIGRPQPMTQPWMDHKVWKDERARVAMVSRMIDGSTFNGNDLHITWYKELQPQIFDILTTSDYILGALLNMCMFARSRSDPPDLPPFNPYDYFPTHMIELLTPPAPAPTQHAPSSTPAGKGKGRGGDNSLAHLSLASRLLANHARTLYSRPDNITELPVLPRLLSKLLRTYQDALQIAPLYMSRIETKAAAIYHWDMPRTWLKRMDHVIWDSFREELMSDKACQNYSPHLHALLADVVNLMKSEHLNDYYKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR95</accession>
    <name>M5FR95_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_82020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GMC oxidoreductase family.</text>
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        <property type="protein sequence ID" value="EJT99615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626513.1">
        <property type="nucleotide sequence ID" value="XM_040776543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR95"/>
    <dbReference type="STRING" id="1858805.M5FR95"/>
    <dbReference type="GeneID" id="63691605"/>
    <dbReference type="HOGENOM" id="CLU_002865_7_2_1"/>
    <dbReference type="OMA" id="EWHERIH"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0274">FAD</keyword>
    <keyword evidence="3 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="540"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="66700" checksum="21FD8C481275979B" modified="2013-05-29" version="1">MGYVFSRPSDVKPFAYLSIPAGSQQYDIILVGAGPAGCVLANRLSEGGKYRVLLIEAGVDNSKETFTKIPATWARTLWTGIDWQYYTTPQKHLDGRSLFWPRGKVLGGSSSINALIYHCGAPADFDAWAEEEGAAGWGYKDLAPYFRLSETYTPKEHHADVDQTHRGTSGPWQTSFSPPTPVLQKYVSAAQTVGIPYTPDLNTPAGTEGVNQLSTFIDQKGHRSSGATAYLTPDVLTRENLTVLTGARCTRVLLLEGKAVGVELVDEQSRTVAKEVYVSEGGEVIVCAGAVNTPQLLMLSGLGPKEELEKVGVQCVRDLPMVGKNLQDHLQTCICIRTKPGRSLDFLATSPLQSLFPLVQWMLGFKGLLTRNGAEVAAFCRMDDPKFGFDGPTHGEYKSNAHPGTPDMEIIAAPVSFVNHGAVKGPWMRGITIDPVLLQPKSKGWVTLRSNDVWEYPEIEPNYFSDPSDYQCLVRGVRVALRIARSSPLVEEFDLRTGKHPNVCKDTEEDCYNMGDSKEEDLSDEEIGEWVKRKAETLYHPCCSARMGKSPEDSAVDLELRVHGIDRLRLVDTSVFPRIVSGHTTAPVIAVAEKAAVLIRSALAGREGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRQ7</accession>
    <name>M5FRQ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRQ7"/>
    <dbReference type="GeneID" id="63689040"/>
    <dbReference type="HOGENOM" id="CLU_2654460_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="76" mass="9285" checksum="FA77DF32E19D00F0" modified="2013-05-29" version="1">MLLLPCLWREKSLGVRMQLRELRTLGSYPQKHQHQQQQQNQQTQTQTQNQQQNQQKQKQEKQTQKEKDKEKEKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRT1</accession>
    <name>M5FRT1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626828.1">
        <property type="nucleotide sequence ID" value="XM_040773252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRT1"/>
    <dbReference type="GeneID" id="63688314"/>
    <dbReference type="HOGENOM" id="CLU_1981542_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="14047" checksum="B452F43B3A3672D2" modified="2013-05-29" version="1">MPGSPTSPTSPTSPTSPVSPNIVRINDDICKQLERASSELREAYHASGYGGANEWARGWTELVDTILRIEQFGLLTDTSRSKALNACRKCLALRIAVDDIYIHADRLRTVLDPSTRYTDYPEAFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS22</accession>
    <name>M5FS22_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_109518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626993.1">
        <property type="nucleotide sequence ID" value="XM_040768892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS22"/>
    <dbReference type="STRING" id="1858805.M5FS22"/>
    <dbReference type="GeneID" id="63683954"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="NYLTTHK"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="34712" checksum="9DC7252468C2DED2" modified="2013-05-29" version="1">MGQSFSEMFPPKTKWLPDQIPDQTGKVAIVTGGNTGLGFATCRHLLEHNTRVYLAARSPAKAEEAIQHLKDLTKKEDIHFLQLDLADLPSVKKAADEFKAKEKRLDMLFNSGGVMIPPKSMLTAQGYDLQFGTNTIGHGVFTFFLLPVLLETAKETGDVRVVNTSSNGHAFAPKGGIAWDQVKDGLAREKAWNDWTSYGMSKFGNVLFSKELARRYADQGIVSTSLNPGAIRTDLQRHLKSKRIQAWIIDKLLYPLEPYGPLTQLYAGTAPEAKSLSGKYLIPWARVGVARPDTGDVEQAKELWALIEEEAGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSI0</accession>
    <name>M5FSI0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24371</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625736.1">
        <property type="nucleotide sequence ID" value="XM_040773661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSI0"/>
    <dbReference type="STRING" id="1858805.M5FSI0"/>
    <dbReference type="GeneID" id="63688723"/>
    <dbReference type="HOGENOM" id="CLU_032263_2_0_1"/>
    <dbReference type="OMA" id="AYFRTRP"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="9">
        <location>
            <begin position="154"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="22431" checksum="4D7B04BF0A196AB9" modified="2013-05-29" version="1">MTQFQAWFEAAIEAGVREPEAMSLTTAATTSSRIPGAAIPSTRIVLLKQSDPRGFVFYTNYSSRKSKELIENPYASLCFYWREIHRSVRVVGKVEKISNDESDEYFGTRPRGSQIGAWASPQSNVVKEGELAARVKHLERKFPDGQQVQRPEGWGGWRVVPFEVEFWEGKPSRLHNRVRYLANDKEAGAWEIDRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTA6</accession>
    <name>M5FTA6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627743.1">
        <property type="nucleotide sequence ID" value="XM_040768758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTA6"/>
    <dbReference type="GeneID" id="63683820"/>
    <dbReference type="HOGENOM" id="CLU_2277381_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11109" checksum="A3502EF3D47726BD" modified="2013-05-29" version="1">MSTSQRQRSALDLRNRVQFGMATEGLTLEHACMDLSTSLQNSVNIRASSGVSASPDVPDVSDTLLIEPIIPLDLKEVAQFLACFGFLRLYCNGAFIMRRGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTK7</accession>
    <name>M5FTK7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zf-DNL-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_60266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623474.1">
        <property type="nucleotide sequence ID" value="XM_040775622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTK7"/>
    <dbReference type="STRING" id="1858805.M5FTK7"/>
    <dbReference type="GeneID" id="63690684"/>
    <dbReference type="HOGENOM" id="CLU_093902_6_1_1"/>
    <dbReference type="OMA" id="THEFAKS"/>
    <dbReference type="OrthoDB" id="512667at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT96576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="144" mass="16006" checksum="E6C8F1D3AC79CEF4" modified="2013-05-29" version="1">MHALRTAKVLLQTKARPIPRPPVCRYYRPNPIRFYQTNPDEPKLSLTFTCTAPGCDGHRSSHVFSKRSYEHGVVLVECPGCHNRHLIADHLGWFKDGTEGGKNKTLEEIMAAKGVPVTRGQIVEKGTFEFNGTQAEDGGETKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUD7</accession>
    <name>M5FUD7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_112461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623744.1">
        <property type="nucleotide sequence ID" value="XM_040769423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUD7"/>
    <dbReference type="STRING" id="1858805.M5FUD7"/>
    <dbReference type="GeneID" id="63684485"/>
    <dbReference type="HOGENOM" id="CLU_325201_0_0_1"/>
    <dbReference type="OrthoDB" id="2428527at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="248"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="313"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="870"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="974"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="870"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="881"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="981"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1060" mass="115801" checksum="FA9A9C36F742B715" modified="2013-05-29" version="1">MSGTFRFVMEEPSESGKGQQKKRARLVTACDNCRNKKIKCLRSPASVVCESCKQSSLECTFADRDKYQAEKLGVSYSATSAAPYPTPWREGSAPEEGLGPHRRRSNSLARPAMENGVNGVSRISVDLPSVSSPGAGLNSPLSFESFAQGVSSMQTATPGGASSSGSGAASTGSGANLPTPESPVGQTALATPINPSSGSFNSLLHANRMFAPHHSTLPPNLQGLHNLQGNLLPGIAVQMDRLKQARRGRAGVKLEPGSGVGFRGGRDEYPPSEDEKGELKRISVPFFRYFGATANTPGYRRINVHTHTYEKAAPAVSAGGTTSRDSSPDVPRVSGAPVDGTSGSTNGQNGMNGSNGNGASIDPFTHAVRHPFHRPPLTMPPVFGAPLPPFPTGPHRSASPSLPVDNRPLFDPADDVPTMPHPDHLPHLAELFFDYLGCHFPFLDREEVMRDIKEKKITATLANCIAALGIRFTDRQVLLFQTDVEGLPTRRARAAEKYCMRAKEIITPYLSLPSVEIVQALVLIAWAEFGCGRDSGLWMYSRMAVGMAMDLGLGFEATIQLVTDHPERIRATWWAVILVDRINCWGTGRPIAIPDDAFDTEPPFVPPMQHGYNRSTPPPPGYVFGHLCRLVQLRGRMGDLINNTVKRKLNTSPVDLELTSLQYEMMAFYASLPNDLQFNLANFKLYFQASQGALFLLLHVMFHSVLIVLHRPQLLEDFTPDVPRASMPSVELSRSSARTIVDMVLLTDEQGPLALMGNPFVDLPILTAARSFLEDRKEFPIAQMPMNLIMSKKWPDSSIAKCKQFLAKMSKYWGGVMAVRRILEEQDMSPDGSFDLGRGESGDSQVAPPRPDSELIKQWATKQWRMHVTENRKSHRDNTEDGSNGPVSPSDSQKADMLRFGDSPEGASIGITGTLDTLLGMQDNSSMDALLQNDPANLLRVSFNQAEADFQFSNLPTQYYSIADPVDNFLQTLQGGGGMQLGPPDLQQPQPMNTQQQQSLQPPPQEQHPLMDVTMSDNTNGSFDTDAMLLFQNEIGRFFSIPEHLSRAPSPTLRSEQPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUG2</accession>
    <name>M5FUG2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626012.1">
        <property type="nucleotide sequence ID" value="XM_040770571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUG2"/>
    <dbReference type="GeneID" id="63685633"/>
    <dbReference type="HOGENOM" id="CLU_834249_0_0_1"/>
    <dbReference type="OrthoDB" id="10543281at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="37584" checksum="29557E2B00000382" modified="2013-05-29" version="1">MDGSACDERLGGMWWQGQQKLVSVLGEWSQFRRPLRINSISQLWVPTIRKIMSYQRIRPSTMQVTYFTRWVLPPQAEVLRVDDDEEAGWVEREMGMRLGRLTRREVGELSGPLRQTPRYITHGLAFSSVARPLSPSSSSASSVLYGASTLNTDLSLTSPLLLPSYAFSPLPQILLGRTARAVYRSLTQTRDEHGQSKTALSSLLPQSLPLHAKIPISDRATAAVLRASGWKEVFGGVADVFLDGWTDTPEEEYQEQKAEKRTGMTRAQREELGERRKRQAEENWRLAQEDREIEQGLAPGGDGARGVMQRRERMRVGMSGVFSHPDKIDTWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUK5</accession>
    <name>M5FUK5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626052.1">
        <property type="nucleotide sequence ID" value="XM_040771308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUK5"/>
    <dbReference type="GeneID" id="63686370"/>
    <dbReference type="HOGENOM" id="CLU_1938091_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="130" mass="14168" checksum="0D700138B8ACA6C4" modified="2013-05-29" version="1">MICHISKDARGEASPPSTSTNHQDQESHAEGDETDDTVSILDRRPDAAATSPSAARIYDISLHKFHQELGFKPVVVTGIRDIFYPALGEAVTVLLSHGSGISMDVQVDHLARCSLTQKPYQRAQATRKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUS4</accession>
    <name>M5FUS4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-lysine(4) N-trimethyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.354</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_52844</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="2"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628413.1">
        <property type="nucleotide sequence ID" value="XM_040775134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUS4"/>
    <dbReference type="STRING" id="1858805.M5FUS4"/>
    <dbReference type="GeneID" id="63690196"/>
    <dbReference type="HOGENOM" id="CLU_020840_9_0_1"/>
    <dbReference type="OMA" id="EYECRCG"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="11">
        <location>
            <begin position="25"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="12">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU01516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="164" mass="18592" checksum="E608DE2C9BE35BE9" modified="2013-05-29" version="1">MERSRGGAAPSSELFAFNQLRARKKELKFARSPIHDWGLYALEYIPAGDMVIEYVGEVVRQQVADKREKVYERQGIGSSYLFRIDDDLVVDATMKGNIGRLINHSCSPNCTARIITINSSKKIVIYAKTPIEPGEEITYDYHFPIEQEKIPCLCGSEKCRGFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUZ9</accession>
    <name>M5FUZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_89279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628493.1">
        <property type="nucleotide sequence ID" value="XM_040776903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUZ9"/>
    <dbReference type="STRING" id="1858805.M5FUZ9"/>
    <dbReference type="GeneID" id="63691965"/>
    <dbReference type="HOGENOM" id="CLU_003875_1_0_1"/>
    <dbReference type="OMA" id="WYQVKRD"/>
    <dbReference type="OrthoDB" id="5554140at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF1">
        <property type="entry name" value="RECYCLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="945" mass="106001" checksum="294D27E426426A9E" modified="2013-05-29" version="1">MDKWTAIEPVKLYDKASSTAASVLSRLSGNAPSRAIFIGPLPPELHLLILDYLPLYDLPAIARSSRAFSRLVRDEKLWERKWKALKIEKYALQEVLNELQNEEEHKPPPPRPGHFAVEEESDLATFTVGGDDEFGDFTEAPPTQSTTGTATETFGQFVNTFNNVALDSQSAVPYITAFPSHHTFRSKFVKAHKAFVGLLPKVVTPPELALSHLFPSPAKSLYKGRVLHLLALFLSPAIEPTRIWSAQKDALNSSIRTFNASLVTAFDTSEEKGEDEGMKEAAWASWEVWDGQGEWEMGKTWMEKRDVFFDSDRWDPLRNLTNNTLHLDPMVVFMTNTMESVRKEGSFAIRIFPPSADILLAVTRRVAADVIGEYITPLLSRAREISIPTYLNATPATFKQAWRLVDSIMDVANPPPEAVITRTQAEDVIFRMFEMFMEDYLTEEISSTKKTLDTACDTWDRKVASHTGLYSPNAPHFLKNPAQVKRNVLASFADVLLLPVQVAATGGTAVAKGISKLTPQQRADKNKPEANGYRTPLADKDDPTAFDLTMADIDNPNEHDQDHDTHPHPTPVPAHVVNGSRASLSLVGSGPGSRSGTPVPGPRPSTPLPSSFDRLELLLSLDVALELIHAVRDSLARVQTFQAYPGTYGYRVRDTFDQLFVLLLQAMGDRHICPAFEKAEEQMKTYKADEHEISTSVAPLLQFFELVHLADTIQSMVQVFFDKELSAHIDRTDFMNDVIREKKRFENSLDDAVASGMNAGTEVLMNQVEHIIWSRTGPREYYPPEGPPLELGPTEGCREAIQCLEMHCKLLKGSTSKDVLEVFYQEVGIRLHGIIQKHLKRQIISLEGGFQVIADLNAYYSFIASLRVQQITQDFSNLKMLGHVFIVSDAKDLAQIVRDVTRYGGSFRPEDVYEFIQRRADWKKIEKTVDKTMYNLSFKDDCIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV29</accession>
    <name>M5FV29_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_18877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624049.1">
        <property type="nucleotide sequence ID" value="XM_040771403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV29"/>
    <dbReference type="STRING" id="1858805.M5FV29"/>
    <dbReference type="GeneID" id="63686465"/>
    <dbReference type="HOGENOM" id="CLU_026591_1_0_1"/>
    <dbReference type="OMA" id="NENMASQ"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="147"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="416" mass="45626" checksum="0A555F89EB6BDC52" modified="2013-05-29" version="1">MTQPQMDAARQSMAEHVGRSSVTIDHRFFDLDVARFLLQCAAITYERTSGPVQQAVQTVKNAFPSKKCLQSHGHHPKPAGEQALGILGERGTQEMMSSLHESRGETQLPPWANSMVPSIKYSTVSELNGTDSAFCGIFFDPASTWIVLAFKGTDPTEFSEWASDFEYSPREAGNRITGFGQVHGGFYDRLFTAAAAERAPFDTIASAVRAVADELSAAHSTSKINLFITGHSLGCAMASLAYATPSSAMRISLLRQSFVTQNLLLPSTSVWIRPRHMRTIPTSDLSGVLLNRGDVVATALPSFGDDRHTGTLRDLFAFAHLGAEFRMGSQSQPSYVKGGSLKPDTWVTVRSKLDRGTVNIMNAQGMAPVIRWTQEIPLIGRLVAHATTMYWDAITQLQVGRAHWAGSHWDIKRVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVA6</accession>
    <name>M5FVA6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_15758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628613.1">
        <property type="nucleotide sequence ID" value="XM_040771135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVA6"/>
    <dbReference type="GeneID" id="63686197"/>
    <dbReference type="HOGENOM" id="CLU_034763_1_0_1"/>
    <dbReference type="OMA" id="ENDFAFC"/>
    <dbReference type="OrthoDB" id="1743579at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067358" evidence="1">
        <location>
            <begin position="17"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="397" mass="41908" checksum="5F823F47EDDFFCE0" modified="2013-05-29" version="1">MLAFLSVALSTVGALAQQLPSVFPISSSLVPGPPSAVCTRSTYNITLLTCTYTIVPFSSNIGPSPNQTIITNLFQTYITSPTNFTAGYHTPTGLASASNSAGSYLISGTLCQPLFGYEHEGTVQLLVHGIPFDSQYWDFQYDPELYSYVWAASAAGYTTFRYDRLGTGLSEHPIDGLNVVQADTDVQILSSIASLLRSGTLTGTGYNKILLAGHSYGSVQATALASRTPAAVDGTIATGFSAYGGAVPLFLASGLWSSAAQVAPYACASLASTYLLPTVPQAAQMNFYYYPGYDESVFVYDAAMPQPVTVGVMFTLETVAGAASNFTGPVLLVTGAQNLPFCGPSNQTILQETGTALFPASKYSYYAPELTGHNVNLHLSAPGTYAAMIEWVLENGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVH0</accession>
    <name>M5FVH0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627186.1">
        <property type="nucleotide sequence ID" value="XM_040768792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVH0"/>
    <dbReference type="GeneID" id="63683854"/>
    <dbReference type="HOGENOM" id="CLU_1547529_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="19687" checksum="E073C46F84EB9739" modified="2013-05-29" version="1">MLTMYHPPEQERVKASERRLEGREVVSAVAPNAAERVSVALAPVALPGLMRLPRLPTADGLTRKWVSDVKPGLLEFAIDVRAEITIVAFGPQTSRIRALDPRKMYRIERPRVQEAAEAFRRVPHKSQLILEEHGVITEIHDPRIPRIFFAFRYLNTIERLRVNEIIDVLAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVJ6</accession>
    <name>M5FVJ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_37114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626532.1">
        <property type="nucleotide sequence ID" value="XM_040774424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVJ6"/>
    <dbReference type="STRING" id="1858805.M5FVJ6"/>
    <dbReference type="GeneID" id="63689486"/>
    <dbReference type="HOGENOM" id="CLU_005049_5_0_1"/>
    <dbReference type="OMA" id="STHHKER"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="2"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="362" mass="40595" checksum="C78D7D611282B34A" modified="2013-05-29" version="1" fragment="single">PRRLIVCFDGTANLFDDANTNIVHLVSYLKKDDLQEQQVYYQTGVGTYIPPGIFMRFMVNFLKKMDEGFAWDISNHIMGGYKFLMNNWTPGSKISIFGFSRGAYTARALAGMLKKVGLLSRGNDEQIPFAYNMYTDTSATGWTQSRGFKRAFSHEVHVDFLGVWDTVASVGVFTVRDLPLSSSDRHIRVFRHAISLDERRCKFKENLWQAPFIPPGTSQTLHEGETESASLSDHHKYVPVPTDISMEEEEGSIDFSLEQRAPTDVLEVWFSGGHGDVGGGCAQNTERFSANRIPLTWMIREIVLANTGIVFDEAALAADGIILPSPNPQRVLARDTAGHDTVALISDQLKLVRSWWIIEILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVK3</accession>
    <name>M5FVK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627231.1">
        <property type="nucleotide sequence ID" value="XM_040768802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVK3"/>
    <dbReference type="STRING" id="1858805.M5FVK3"/>
    <dbReference type="GeneID" id="63683864"/>
    <dbReference type="HOGENOM" id="CLU_558999_0_0_1"/>
    <dbReference type="OrthoDB" id="2506088at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="488" mass="54510" checksum="635565CE87340228" modified="2013-05-29" version="1">MIQTAADVKRGMNTVDAIGQRHGVANRFAEPVIAMLRRLCDGLKAERRLSEGDMQRILHERLSAYSNDHAVNPLLRIPGFNVHQSTPVKLLHTFLLGLVKSTAPPYTNAHGDIERGRLVRAQAGTSLHDSVLTVTHRQTLQGHGTLHGTVPHEYIDAWVLLGLAGAVFWKTDIAAKDEYLMDLWETLTALVYAVSRVDATKIISKPKLHIILHLAEHVERNGPALLFQTERYESSNTVFQHCSMLSNRQALSRDILTTLVHHSQVRHIVSGGWWHDAAEDKWVRAGDDVRAAVKGQVIFQRLLGMPKNSTNLPGHLPVQRPVNHVHWCQTKAGEQLPDAYPAQTRCLRYPKAIATNSDHVPIRGFVIHKQGVDQEYGRYSLPSMGPIVPSVQEADLEASQPPEPPGEYDVVEGREGMLDNLTHSRLDEHKGNSNAVRQIGITRNYKQMIRTVQADLGLAKEVIDTVTAVYLDNPRRSKSAKLDNPWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVR3</accession>
    <name>M5FVR3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="10">AK6</shortName>
            <ecNumber evidence="10">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="10">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_52292</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="10"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628823.1">
        <property type="nucleotide sequence ID" value="XM_040775097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVR3"/>
    <dbReference type="STRING" id="1858805.M5FVR3"/>
    <dbReference type="GeneID" id="63690159"/>
    <dbReference type="HOGENOM" id="CLU_079096_3_1_1"/>
    <dbReference type="OMA" id="QCEIFGT"/>
    <dbReference type="OrthoDB" id="10251185at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000372">
        <property type="entry name" value="Adenylate kinase isoenzyme 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="10">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="10">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="184" mass="21222" checksum="00DAA72293C5383D" modified="2013-05-29" version="1">MISGPIIVMTGTPGTGKTSTAQLLAASSASLDPPFSLRHINVGDLIKDKSLHDGWDEEWQSWNVNEDKLERIIEERPAGEGLILDWHTCDAYPERWADLVVVLRCDHTTLWERLEKRNYPLNKIQENNESEIMQVVLDEALLSYPAEIVVELKSDTPEDMENNVDRILQWAKVWREERAQEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW26</accession>
    <name>M5FW26_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626752.1">
        <property type="nucleotide sequence ID" value="XM_040768857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW26"/>
    <dbReference type="STRING" id="1858805.M5FW26"/>
    <dbReference type="GeneID" id="63683919"/>
    <dbReference type="HOGENOM" id="CLU_133353_0_0_1"/>
    <dbReference type="OrthoDB" id="2562934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="132" mass="14285" checksum="23B00C9D0FCFF74B" modified="2013-05-29" version="1">MSSTTPLDVFVENLLAAMFFETDDEKAIQAFEAGLSEDIRIEVNGAILPRPVYLGIVKGIRKDNVATDLGNPTLAMHVEDAEKQTGTVAQCGKFTLKNKSTGEEKTSSAGTIAKVEFRDGKRVMTSLTEVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW58</accession>
    <name>M5FW58_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624504.1">
        <property type="nucleotide sequence ID" value="XM_040773949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW58"/>
    <dbReference type="STRING" id="1858805.M5FW58"/>
    <dbReference type="GeneID" id="63689011"/>
    <dbReference type="HOGENOM" id="CLU_040908_0_1_1"/>
    <dbReference type="OMA" id="KRCKPRS"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067359" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="3">
        <location>
            <begin position="88"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="34641" checksum="B920F192F7FCD4D6" modified="2013-05-29" version="1">MARLSLLISLISLALLVSASGQEAMARSAHKKRGNCTPKSAAASSSSTSDSTQPTSSTDDSQPSSTSVAPAPVSTPQGPASSGGEKCGLGWPNGDDGTILTDHGNCLYYHTWSVWPVNSGGKMSFAPIFWGPDKADEWSANILNAGANVALFFNEPNESGQSNIDPNSAVPYWRNNMQWLKDQHGYRLGSAATSSNPNGMDWTNTFMSACPDCTIDFMCLHYYGTDAGDFQTYVNLWHTTFNRNIWVTEFACQNFNGGPQCDDVPGFMSQTVSWLDSQDFVEYHFWFGMMRDMQGVNPADGLMNQDGSLSALGDQYVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWX0</accession>
    <name>M5FWX0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629380.1">
        <property type="nucleotide sequence ID" value="XM_040767419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWX0"/>
    <dbReference type="GeneID" id="63682481"/>
    <dbReference type="HOGENOM" id="CLU_1117971_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="249" mass="28095" checksum="538D68828DD0C697" modified="2013-05-29" version="1" fragment="single">MDSISKHWAAAESARGRLPEFYQNKYLTKRGDTLIKPSTRDIYKIRRLAKCMLHEVGHWTSSNKLWQATLAVVKDTCTKYEYGRLILFLACNLRSSSHSISFTGFIRTSLEDALAGAGFPSYRYIPSQQLGCATRKAFPEFIKLNEVHCATVLEYDLGTYTAELGRMARHQAARRFFYLHFDIRGSINIKPRRNLTGIGAGLQTNADVLAYIMQVGKLSLRDVQHLSHVSRSEGYPRGGSRAQSSSSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWZ9</accession>
    <name>M5FWZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Replication factor A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627846.1">
        <property type="nucleotide sequence ID" value="XM_040771190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWZ9"/>
    <dbReference type="STRING" id="1858805.M5FWZ9"/>
    <dbReference type="GeneID" id="63686252"/>
    <dbReference type="HOGENOM" id="CLU_031807_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication factor A C-terminal" evidence="1">
        <location>
            <begin position="412"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="578" mass="63036" checksum="217E16DC5BDFA489" modified="2013-05-29" version="1">MPTIIPGWEAANAPYLGYLHSLDLVATPDKMAPANHLLMQAATQNQMGRTVFMIIGVGQVPPKLVALHAPIVAQPAPPIPTQIDQLHLISSPLDPPIMQHYTANPTLLPGPLPQPPVQPLAPPGLGMMPLFANINTIVAFMKGLNVCICITQVKPKEHGTIDILCHDATGEIDLDVCRACDLQASDIEEGKIYEIYNVGAMALVQHWCPSFHVTQLNFNNWNNDGLIPLYFFNYHPIIQLPSIPDKKIINVPCIIANTSNVMHGKAPRHASFGHASAAPMMRIDMWLVDDSGRSVCLVAFNEFWAELEGTDGCVALLKNIAVDCTYGMSLKTVASYTKVFFEPAIIPGYADLTAWWEAAKDNPSQWHLLSTSCSADGTIALAACSLMTAPPIVNIHQVHAECLDQAAKAMTFHIAGTLDINKQCSVTYAGCATLDCNRKVHQSFLDPNNLHYHCPTGKQSFSVPIAKYCLSFTIIDGNSDCAPATAFNTAATLLLQINMGTMYDVFADEHCYQPVHSFNLGQAMMTVHASTPSTGYWKGKTQWIVMEFFNMGHVYDLSQSLAQPVSLCSLTFTIVSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX06</accession>
    <name>M5FX06_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="7">5.5.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Myo-inositol 1-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_94350</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="7"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629420.1">
        <property type="nucleotide sequence ID" value="XM_040777215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX06"/>
    <dbReference type="STRING" id="1858805.M5FX06"/>
    <dbReference type="GeneID" id="63692277"/>
    <dbReference type="HOGENOM" id="CLU_021486_2_0_1"/>
    <dbReference type="OMA" id="VYVPMKE"/>
    <dbReference type="OrthoDB" id="2887at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000334">
        <property type="entry name" value="Inositol-3-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000069">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000055">
        <property type="entry name" value="Putative myo-inositol-1-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="19">
        <location>
            <begin position="336"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00070063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJU02526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="552" mass="60670" checksum="56DD4BE51A6D4D5B" modified="2013-05-29" version="1">MAPHATGPAPELGPYTAPQPPVHPTAERRDTVVLVDSDRTTYTEEHITAKFTYRGAQVTREGGDIKVTPTKEEFEFRTKRKVPKLGIMIIGLGGNNGSTFTATILANKNHVTWYTKEGIQVPDYVGSVLRASTVRLGTDPGTGKDFHLPVCDLLPMVHPNDITIGGWDISSLPLDEAMRRAEVLPYDLQRQLVPLMRGIKPLPSVYYPSFIAANQGERADNVIPGLSKRDHLDHLRKDIREFKVANNLDQVIVFWSANTERYSAIIPGVNDTKEALLASIDASHPEVSPSTLFGVAAVLEGVPYINGAPQNTFVPGLIQLAESRRAFIAGDDLKSGQTKMKSVLAEFLVNAGIKPLSIASYNHLGNNDGYNLSAEPQFKSKEISKSSVVDDMVAANHLLYKPAAQMAKESGDPKAKPEHPDHIIVIKYVPAVGDSKRALDEYYSRILMGGRSTISIMNECEDSLLATPLIMDLCLLAELLTRVQYRTTPEEEFMPLYSVLSLLSYMLKAPLVKPGTEVVNALSRQRSALEQFLKACLGLDNSGDLLLETRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX62</accession>
    <name>M5FX62_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_23249</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627227.1">
        <property type="nucleotide sequence ID" value="XM_040773172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX62"/>
    <dbReference type="GeneID" id="63688234"/>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OMA" id="IAWFLSW"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="30120" checksum="66EE1B8EAACB5F1F" modified="2013-05-29" version="1">MTGNQALEVNPPNAQIDINTNGSDWLWAAFALFMFSDLCMISWMWFRRTAQRVFHLLPIIILSIASVVYFTMAADLGSTPITAEFYGNHHQTYAGEPATRAIWYVRYVGWVLTMPLVTLAALLTTGLAATEVSSTLFMQVVAFVSFLVGALVSSTYKWGYFTFGTVALIYVVVQLLVPARVAAGTIGDDVRSIFTRSAACLSFLLMLYPIAWGLADGGNVITSDGEMVFYAVLDIMVQPVFLFALLFQLRSIDVARFGLAPRHVIVNEKAAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXC2</accession>
    <name>M5FXC2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Replication factor-A protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625024.1">
        <property type="nucleotide sequence ID" value="XM_040770681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXC2"/>
    <dbReference type="GeneID" id="63685743"/>
    <dbReference type="HOGENOM" id="CLU_1695412_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17096" checksum="ECC5E00E5BADAFE8" modified="2013-05-29" version="1">MSQYSLTRNACELMVQGLQNHVGLVVQVLLVAPLAQRNPYEPAQYRVELGDGEHWVEATLNYNLNALFRANKICSLMVIRVDSFTRVLYESGKVAKALEGSDGLKRMDCVDRSGDVRALASAPSGDVLFDCWDNEPISDEPISYRTITSATLGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXH8</accession>
    <name>M5FXH8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629600.1">
        <property type="nucleotide sequence ID" value="XM_040768328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXH8"/>
    <dbReference type="STRING" id="1858805.M5FXH8"/>
    <dbReference type="GeneID" id="63683390"/>
    <dbReference type="HOGENOM" id="CLU_052201_0_0_1"/>
    <dbReference type="OMA" id="HSRAITY"/>
    <dbReference type="OrthoDB" id="621413at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF106">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="501" mass="55501" checksum="72D5B11FB73EECC7" modified="2013-05-29" version="1">MRKRNQFSEAMQEYRNSIERYQIIGDTLGTAQCMQSIGDILRMQFHNQEATAKLEEARAQFRAIGSRLGVAQCTRSIGDIMVTQVQYTEATACLQDAVKEFQVISHRLGAAQCKQIIGEVLRLQSKDEDAITQLEEARTEFRAVGDRLGVAQCTQGIGECLQLDDREAAYVLLEEARAEFRATGSRIDIAQCVQAIANTQLTEGLYDEAAAKLEEAKTEFRAIGACLGVAQCTQNLGDILRMQGQYDGAAESLEEARRVFRAIGCRRSTIQCTQSIGNILPMQAKYEEASAILEEASKEFREAGDRMGSAQCQRSIGIIFAMQGRYEDATATLEETQAEFRAIGSRVGFAQCMQKIGDILGKQAQYEQATTKLEEARTEFRAIGSRLGATQCTQSIGDLLRMQARYRQATTTVDEARSEFQAMGDRLGVTQCTKIKGEILGMRAKYEEAIESLEEAKTQFQAIKLPHLAQECSKSLDDILGIRKREGEVVLTTETVALAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN3</accession>
    <name>M5FXN3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629680.1">
        <property type="nucleotide sequence ID" value="XM_040772534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN3"/>
    <dbReference type="STRING" id="1858805.M5FXN3"/>
    <dbReference type="GeneID" id="63687596"/>
    <dbReference type="HOGENOM" id="CLU_2605970_0_0_1"/>
    <dbReference type="OrthoDB" id="2555959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="79" mass="8596" checksum="D114B3807407224C" modified="2013-05-29" version="1">MAKSRVTPPQTPSSRTAPAKKVAPSSEKKPAISMWQSYNALSPRSRMIFGISLFIFAGAGLYISDKLEERLLASSPGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXW0</accession>
    <name>M5FXW0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Myosin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_21837</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629775.1">
        <property type="nucleotide sequence ID" value="XM_040772562.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FXW0"/>
    <dbReference type="GeneID" id="63687624"/>
    <dbReference type="HOGENOM" id="CLU_000192_7_6_1"/>
    <dbReference type="OMA" id="NDQENQC"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01378">
        <property type="entry name" value="MYSc_Myo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11858">
        <property type="entry name" value="SH3_Myosin-I_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.720:FF:000015">
        <property type="entry name" value="Myosin I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.4820:FF:000004">
        <property type="entry name" value="Myosin IE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.530:FF:000007">
        <property type="entry name" value="Myosin IE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035535">
        <property type="entry name" value="Fungal_myosin-I_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010926">
        <property type="entry name" value="Myosin_TH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036072">
        <property type="entry name" value="MYSc_Myo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF837">
        <property type="entry name" value="MYOSIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06017">
        <property type="entry name" value="Myosin_TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51757">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 16" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 16" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 15" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="Myosin motor" evidence="19">
        <location>
            <begin position="43"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="TH1" evidence="20">
        <location>
            <begin position="785"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="18">
        <location>
            <begin position="1066"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="16">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="949"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1041"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1123"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1214"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="960"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1001"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1052"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1126"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1228"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1239"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="136"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU02881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1313" mass="143475" checksum="2E10E6A04A504755" modified="2013-05-29" version="1">MAISKKSGKKGGVAPTVAKPVKKTAGQQFVKADWKEGFKKKQTGVSDMTLLTTISNEAVNENLQKRWLNGEIYTYIGAVLISVNPFRDLGIYTKDVLQSYKGKNRLEMPPHVFAIAESAYYNMSAYKENQCVIITGESGAGKTEAAKQIMAYIAAVSGTGEGADGGQRIGEIKEMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIMFNERGEPVGAQITNYLLEKGRVVGQIDNERDFHIFYQFTKGASDEQREMFGLQGPESYVYTSRSKCLDVQGINDVKDFADTIKAMGVIGLSQQEQTEIFRVLAIVLWLGNVQFEEMDDGNARIADKGVTDFIGYLMQCEGAAVEKVLIQKIMETQRGGRRGSVYEVPLNPAQASAGRDALSKALYNNLFEWIVQRVNVSLAPQTSHSQLIGVLDIYGFEIFEDNSFEQLCINYVNEKLQQIFIELTLKTEQEEYVREQIKWTPIKYFNNKVVCDLIEERRPPGIFAALNDACATAHADPAAADQSFIQRLSVLSSNQHFESRGDKFLVRHYAGDVMYNIPGMTDKNKDQLVKDILDLMDKSGNTFLHTIFPDRPDPNSKKRPPTAGDRIKSSASALVENLMRAQPSYIRTIKPNQNRSSSEYDVKAVLHQIKYLGLQENIRVRRAGFAYRNTFEKVVERFYLLSKATSYAGDYIWQGDPKSGCEKILIDTGIAKDEWQMGVTKAFIKNPETLFALETMRDRYWHNMAARIQRAWRNYWRYKNECARRIQRFWKNNKEAIVYAQARDYANTILAGRKERRRMSILGSRKFLGDYLDVGKADPLMLKGSAGLASGETVAFSCRAEVLISKFGRTSKLTPRFLVLTDKAVYILAAVAHDGQPVVQLQRKMPLVTIKSVSLSNLRDDWFALNGPISDEGDPLMTCVLKTEFVADLVKLSNGSMNVHIGPTIEYNQKKDKKRVIKFVKDENSRGDPYKSQTVSVTTGEPTNSVPRPLPKPKPGQVRPITSGKLLKAGGPSSKPSSTSKPKPQALPGHSVPIASVKPVIPVAVSAAAQPASTSAVKRHSMAPPPPPPPPPVATAPEVPMYKALFDFTGQEGEMSLKKGALVEVEEKDDNGWWLVKLNGKEGWAPSNYLELVPPKSKAPPTPPAPARRPPPAAPQAVPVAAYIPAAPKPPPAPAMPTQNGLPSGMNPAAAAIKAAAAGGGLGKPSGMTPAAAAIKAAAAGRDGATGGLKHVKPPTAPTVPTVPTVPKVPKAPGPPVATKPKPALAPKPGAPPVATKPPVPGGIPKPPPPPPMPGQVKKPAGAVGQMDLAAALQRRAQRIADDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY78</accession>
    <name>M5FY78_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628386.1">
        <property type="nucleotide sequence ID" value="XM_040771169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY78"/>
    <dbReference type="GeneID" id="63686231"/>
    <dbReference type="HOGENOM" id="CLU_479806_0_0_1"/>
    <dbReference type="OrthoDB" id="3224257at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="386"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="568" mass="60699" checksum="2C07FB2B1808CB70" modified="2013-05-29" version="1">MILRVVPPSPGLTILFTLSFPALPSPLPFPPAWSSTLSLAISHNLAPPPSAHALDRACATVELLHSVTFDIARSQVDCRMVDNDLVSFPLSQPLRSALDKVCADVARSTEESEREKRGLPPSSPSPTQAPGSGSGSRAALTSPSLLSLLSSFLPFSPPPTPTHSLAGPPTPASRTFRRSARSTLVDAFARYVQPELTQRVHKSAGGWGAWSALKALRKTSLELEDLLAPSEPPSPAGSTSSSVTSCSSSEFPALPPTPALSHSSSSSPSTPSTSLTFSTPLSASQLSAYSRLTSRVQELKGLLAVLEEKEREWREEGPRKREMGRRSPLVNVLRLEEDVDEPVPVPVQVPIHGVGRGARERSKISFPSLPSTLPAPPRSTRLTVRNPAPNSNANGNANFRPNPNSNSNSNSKPSLPALSVQRPKLTRGVPYTSFPPSPSPSPTPTPTSIAKRRPSLPLATAFRIPPDGRGAKVVVVDPSDPSEQDGMDVDVDVDVDVDVELGLGKRLFRGMGMGMEGDVDEEDVHMQEIEIEMEMDVVDAVGPEVGDGDRDKRRRALDLPRGELLGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY94</accession>
    <name>M5FY94_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_54355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627687.1">
        <property type="nucleotide sequence ID" value="XM_040775245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY94"/>
    <dbReference type="STRING" id="1858805.M5FY94"/>
    <dbReference type="GeneID" id="63690307"/>
    <dbReference type="HOGENOM" id="CLU_029501_2_0_1"/>
    <dbReference type="OMA" id="VHEVYQQ"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="62"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="275" mass="30402" checksum="2B5A7AACF4C4C4C5" modified="2013-05-29" version="1">MALAPHNTSQLEALHRDPALHESTYVHAVYDSIADHFSQTRYKPWPIIAAFLASLAPGSIGLDSGCGNGKYLPLDQGGKIMLVGLDRSLGLLAHAQWAGGKERHVVRGDVMNVCWRPGAFDFAISIATIHHLCTLERRRQAVQALLQAVSSSDGRVLIYVWATEQDELSKRIVPVDPEKAGEKVQDVFVPWKKAAVQRANGAGTETETETELHQRYYHLFTKDELGDLVREAAKCLGLHILQGEDSSESNGLRIVQEGWERSNWYIELLLTTAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYH6</accession>
    <name>M5FYH6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_89289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628471.1">
        <property type="nucleotide sequence ID" value="XM_040776904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYH6"/>
    <dbReference type="GeneID" id="63691966"/>
    <dbReference type="HOGENOM" id="CLU_2775886_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="69" mass="7737" checksum="9CEE59D770C2CFA9" modified="2013-05-29" version="1">MFGAVEANGDAENGRRGRSADRGIRDGREEEHTHEEDEEAQADRDVVERAHVKRHKNTIRGMSSCAVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ45</accession>
    <name>M5FZ45_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pkinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_34302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625744.1">
        <property type="nucleotide sequence ID" value="XM_040774379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ45"/>
    <dbReference type="STRING" id="1858805.M5FZ45"/>
    <dbReference type="GeneID" id="63689441"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="HVMLCAS"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="31411" checksum="525AE7648AD1BF89" modified="2013-05-29" version="1" fragment="single">LANAYQELGRELGSEKIRVVGNYTLGKVIGEGSHFLCTYGKVRLGTHRITSTRVAIKQIPKAMSAQLTREIHHHRQLHHPHVTQLYEVIATESSIWLVTELCTGGELFDYLVEKGRLSERETRMLFGQLCLAVEYIHEKGVVHRDLKLENVLLDEYCHVKLGDFGFTREYEAGRLLDTFCGTTGYASPEMLLGNKYSGREVDIWSLGVILYSLLCGGLPFDDDDEIIMRNRVIHGVYPEPDWLSEDARDLIRHILVKKPEARYSVKQILSHRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZC2</accession>
    <name>M5FZC2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit RPC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628761.1">
        <property type="nucleotide sequence ID" value="XM_040768507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZC2"/>
    <dbReference type="STRING" id="1858805.M5FZC2"/>
    <dbReference type="GeneID" id="63683569"/>
    <dbReference type="HOGENOM" id="CLU_055683_1_0_1"/>
    <dbReference type="OMA" id="VFQYPIY"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33681" checksum="9F1E88E0ABCB086B" modified="2013-05-29" version="1">MSSDILMADAGPSQPQDVHMIDPDAPIATIPIHLSNRLAPNLSIHQFPLLTQLRVPASAEAAGRKIKARHKPKSGIVEVRLPLDTREEVYNEERGNELGLGREEEEAESSASGIRRKKKSRSDEEIHKRLDEVRLVSQSVKGAKPRTTNMVGVLRDNTLYLHPLEHTYQLRPSLDYLDVLAARDKESRKKDYDDDDEEEGKDGGGRGKPRDVREVIGTVKAPGSDKDGLGGTSGVRKEMLMLMRDEKEEKWHDLEWNDSNTERANEIYETLFPNTQHVLKSASKLGDVLTSIHGLSEPSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR6</accession>
    <name>M5FZR6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_56459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR6"/>
    <dbReference type="GeneID" id="63690435"/>
    <dbReference type="HOGENOM" id="CLU_1173055_0_0_1"/>
    <dbReference type="OMA" id="EDQRMIQ"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF09729">
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        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="183"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="26"/>
        </location>
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            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="237" mass="26685" checksum="56A2AB858FB5D0D0" modified="2013-05-29" version="1" fragment="single">MGKNKGDGYPSPAQQAAIAAAAAAPAHPKEDDTGPVAPTHACLRAFPLFSPSDPARTHLMQGVRNSHDAHVIMEAVRMDLLPLVNRRLTPAQRKELGANGSVYVWERVEGHPHAIKRWDDSVRWRPGLNINPFEIFEERGDMPNQDRKNAKTRPDRNLGRPKGTSYLRPSRRPDVPIKPNGMTRQVYTADVQSATDPAPRRWHLVCYWRKSELDMIPTIEQDRTLARVRVPAGVYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_22569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772860.1"/>
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    <dbReference type="STRING" id="1858805.M5FZV8"/>
    <dbReference type="GeneID" id="63687922"/>
    <dbReference type="HOGENOM" id="CLU_032490_1_0_1"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="301" mass="34051" checksum="69A0E36474DB232D" modified="2013-05-29" version="1">MLLEKYGAVDEMYVWEAYNHGDAALINANNLGDTFDWADGARDVLQFLTFHRPLVHQRNAPTHLPHHAREDCPRPVIGVGHSHGGEIITRAALHDPTLFSALILIDPVIMMETLSTPTRRESMKNRDELLLRRTLARRAVWPSREEAEKFFAQAPFFRSHHPAVLSLYVSHGLASLPTSAQGSSSSNCVMLKESPFDEATFYSEPRAPAETWFLLPLLDPPVELRWVMGNDMENYQGGEEHVRHMVWRRPNNSSNTIVRSAGHFVPQQAPEQLAREIADVLIRQQHSFGQRTSAGQVQARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G014</accession>
    <name>M5G014_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_83058</name>
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    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
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                <person name="Sabat G."/>
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                <person name="Syed K."/>
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                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="M5G014"/>
    <dbReference type="STRING" id="1858805.M5G014"/>
    <dbReference type="GeneID" id="63691671"/>
    <dbReference type="HOGENOM" id="CLU_011106_0_1_1"/>
    <dbReference type="OMA" id="GVLWPKF"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
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        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="138"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="384" mass="42736" checksum="1E07E4B2E65B3F42" modified="2013-05-29" version="1">MLPLSIPRFPFPPSPPSWYAGHMAAFVNSLPKLLSTTSIVLEVRDARLPLTSVNPAFETALRRYWASAELEGKERIIIYAKRDLAERRYEEPLKTMFKKFANQRVMFANTGQRGDVRRVLDAITNIAENNKETHPRAEVLVVGMPNVGKSSLLNALRSSGIQKGKAFRTSATAGLTRKFTGHVKIHEEPDIYVSDTPGVMVPYLGRGEAGSEKGMKLAVTAGIKESLYDPELLASYLLHILPIKANMPFDLPHPYRGLLPEYGGSFANLVPPSHDQTPLLEALAQRLGRVRKGGFPNTNLAAIWLLDWFRKGGAGRWTSDFESAGGLKGVEETVRQWVEQGMGIIGEGESSQNQERRKKIEERRQKRLEKWKKTHGTRAVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G042</accession>
    <name>M5G042_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629016.1">
        <property type="nucleotide sequence ID" value="XM_040772589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G042"/>
    <dbReference type="GeneID" id="63687651"/>
    <dbReference type="HOGENOM" id="CLU_1731410_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="17112" checksum="004671A16CE613ED" modified="2013-05-29" version="1">MTGFGVVSRLASPGHHWVDIIDISEFKKSAEKGREVMFGMHHVLDSYMNRSLVFGTTIARRQTRFWKMSREGLVTTEPIDFHTEALLFIEHTARLAYASTAQLGIDDTAALTQDKERIATISINKETYFIVRTLFQHPAHNICSRAARICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C6</accession>
    <name>M5G0C6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630585.1">
        <property type="nucleotide sequence ID" value="XM_040772281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0C6"/>
    <dbReference type="STRING" id="1858805.M5G0C6"/>
    <dbReference type="GeneID" id="63687343"/>
    <dbReference type="HOGENOM" id="CLU_001305_1_0_1"/>
    <dbReference type="OMA" id="HRWIPFI"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="2"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="21032" checksum="D69B94772CC2738F" modified="2013-05-29" version="1">MVAQPKVDNFVALPSVQEELTGMRQALPEDKLIVLEGERANLVNVTRALGKATWIHFACHGHQEQGNPLESCLVLSDGKLMIDSMIANRFENADSFAFLSACHTARGLPELPDEMLHITAALQCAGFGAVVGSAWAIADKDAPSVASRFYRYLMNQGGELDPTKTADALRVAITALRRSGVPAHRWAPFLHVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0U6</accession>
    <name>M5G0U6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624310.1">
        <property type="nucleotide sequence ID" value="XM_040769314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0U6"/>
    <dbReference type="GeneID" id="63684376"/>
    <dbReference type="HOGENOM" id="CLU_075600_0_0_1"/>
    <dbReference type="OrthoDB" id="782330at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="35994" checksum="3C1586FFB1C3DDBC" modified="2013-05-29" version="1">MAKPNTHKFTAKLEDKHNAMLKTAAIIYLDIVPFSNVVTLLLNSPQSALQEELAAWSVPPEEDEEEDEDEKEFKALLLGFLMSMASLASPLVKAEKGKGKAKEMMPAKSVMLRLNDGVDKMLPAIRVHGRLTKEDSRNVGWMPEETLQCMLCCKHAIVKDSKECHKCDIVEVPKRAVCSMRKAAKKPCSVHTAHLAKAMALPPASVEDLFLPETPEPKPVEETAKKPAEKKKQKPVCSYAPVKPQKCEQEDDKDSVGTSQKQSCLPEAEVEPPVALLRMAEHKMLELRKSLHMAQKAVDVAQKVMDMVTGQVDQVQTLLGRALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0W6</accession>
    <name>M5G0W6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_115193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630785.1">
        <property type="nucleotide sequence ID" value="XM_040769950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0W6"/>
    <dbReference type="STRING" id="1858805.M5G0W6"/>
    <dbReference type="GeneID" id="63685012"/>
    <dbReference type="HOGENOM" id="CLU_019366_1_0_1"/>
    <dbReference type="OMA" id="PFWYWPH"/>
    <dbReference type="OrthoDB" id="3226064at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="11"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="621" mass="69807" checksum="2B8D349AAB6D6E9C" modified="2013-05-29" version="1">MARSSISPGRAVTLESLPPEITQRCLSLCDPVDVAAFAQTSHANRDFVYSAFDQVLWRELFLALFDDPRVTDPPTAALWSRFSKLDLWQKQLCERICARQVLRGLKRKLIASVARAGGRTDDPTSIDVDSADFTGVLKGEKEFSEALRVLVHVFDTARGNVDPKTLPVGMVSSEEDWDSKNVDFVRSTLDHPLLRKLVWDHTPEEAKQASAKLHVHFGLTDWDLTTIAERGKARERVYRLANYHERNRWGPYTGDFTRTPNWEHLEAMMLVVGRNVNERVDDWRLQDGDAPLMGLHAARNYTMPSIEPKAPALEIGDWAGVTGKWYRVVCFMDYRDLWGYNYGDFLAFNPSFMEQYSEAVRVMSFNLKVDSVGVPPKDIGIRGANVQTPPAIHALTRSNHMQDSYFPSAQREDEDENEDSENEEWGKRKEERPDEDEHDRRAHEEIANVYRSAELGKLSPLSAKIIAAKATSTTTSPTSSGSHRSAFSTLFTGSPSSSTSASPESSHLSPAPARMSKRPSLSEQYPTIYFSGSVRSSDAWHPTSHVHGRVEMGEDGTVFWKLTSNYDGQDRWVSEGVQIGGMKSRMGVLGIWSDAFHEHEGPAGPFWFWKAANSDPPPRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Y4</accession>
    <name>M5G0Y4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628702.1">
        <property type="nucleotide sequence ID" value="XM_040770166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Y4"/>
    <dbReference type="GeneID" id="63685228"/>
    <dbReference type="HOGENOM" id="CLU_328185_0_0_1"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="876" mass="97204" checksum="BFAF4D3091BB159D" modified="2013-05-29" version="1">MFSPLRLQATRLATLFGAGILLLTLSILYGSFISPSTDSLDSESDSYYGYYGPALSAASRFFHGSSSDDPSRVTLFTWGGGNKAYALEPLEEYAELASYPVGARPWIPNAVEGGTPEEWTLSREEKERLTHANAEHQAADSQEWGWEFPAPQVDVFDLDKTKWEPPTIEFALVIMGESAAVEAVTMIKGILMHISTPVHLHIVCDEAAMYYIDDRLTLVHRPAYDIHVSYNLLSSSQIWARGARAGIGSTYHAGAGGLAKVFLHEILTETKRAIFIDIDTLFTVDPLLLWKEFDKFKPGQVFALPTLGPGSDELTVCSCSLLLDLEAMRDRFQWVASDLRPQASRTDVAYSSLMSAGLDPHNPPFGDQGVYYAIWRARPELAGHLGLSWDVSHCRNHWGFALDDGDDEMTEEEQVRRRGERMWDVERRMADAPERWPIFPGILHFNCIDNAANSFTYSDIVDFPTWGPVVQVATQYKWTWLNRGDGSAKVDRVMYEDVRFADERWPEGEREGGWTQPEPVDLRLEEGLAFPDPGQEIGYEKTGTLSGGITLPDWDGEAVPPVPAEWATPPLAYDLQSEEATPTYDKLPVYDDSPEYDLQPEYEASPTIGDLPGYDDSVEHETFVPGEESIDQPDDIAPVSEYDPPTNLEQADSAPLVAYPHLDPIISKPEEQPVQEVPPELQRGSWVLGPYHEWIWVEEPSRGPLPTEEELEEPELPSEHGIGFAPAAVPPVEEEHAPFVPVLPRPLEEEAALEDDEGERLKQAIADALAAYAKHAAGASLAPVTLPVPAPRPEAPYPPAYGAPPSLKEADFSLSPVSEEFQPMLEDVADQPTDIPIPAEEPLDEFPAEEPEPVGEWVEDAEGEWTWVPLEPVAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Z3</accession>
    <name>M5G0Z3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_116255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628712.1">
        <property type="nucleotide sequence ID" value="XM_040770169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Z3"/>
    <dbReference type="STRING" id="1858805.M5G0Z3"/>
    <dbReference type="GeneID" id="63685231"/>
    <dbReference type="HOGENOM" id="CLU_792319_0_0_1"/>
    <dbReference type="OrthoDB" id="3164835at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="78"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38845" checksum="F01A022A3E233499" modified="2013-05-29" version="1">MHQAQLHAFSGLYTQWLQRQLQAHVGSLSLPDQVALRLPQPGMLPLSSPGVSTLPPPEELDDEEEKLELPPEFYSSKPDIVLVSLEGVEFPTQKLFLSVGSAFFRRMFEDASSDASTSTSASPDPYTNELERVPWPEKASTIVHLLQLLYPLPKPRFPSLGVTLQLLLSADKWELALPLQRLKDSLLTKWAKERPLRVYGFLCSSGLGTQEEIRAVAEECLARCDPREGRWKRDLEGMSALALSSLLDARDARAAQAQKVVQREVPSHCPHGFPLATAALVGQWKAALGERLARWPTGRVMDGWESIAEVLWPEGVAASCRLCIPTEARRACIEKVAKAQWDIDALPITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1E6</accession>
    <name>M5G1E6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628917.1">
        <property type="nucleotide sequence ID" value="XM_040767437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1E6"/>
    <dbReference type="GeneID" id="63682499"/>
    <dbReference type="HOGENOM" id="CLU_1261470_0_0_1"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067498" description="Protein CPL1-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Protein CPL1-like" evidence="2">
        <location>
            <begin position="163"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="219" mass="22487" checksum="284D6EC42562CEEF" modified="2013-05-29" version="1">MLAQHLTSLIVIVGLAALVRGFQEVGGSPCTTVGSACSWSYLNSGGSTVNANGFCAPNGFCGDNGATCSTSDNCYDYCGNGVCGGLGATCNTKAAFSHNQFNVACYTNGGYTCNAEGSNGSCVSSTSPASRRRARQQLSVNGPAACRRNTDTLCPNVHGLEAECVDLASDFENCGKCGKECGDMEGGATVECVKGRCLAKSCRRGWMLLGNVCVRTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Z8</accession>
    <name>M5G1Z8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_99923</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629137.1">
        <property type="nucleotide sequence ID" value="XM_040777640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Z8"/>
    <dbReference type="STRING" id="1858805.M5G1Z8"/>
    <dbReference type="GeneID" id="63692702"/>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_1"/>
    <dbReference type="OMA" id="PEMAFYD"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003037">
        <property type="entry name" value="PRK03932.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="278"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="536" mass="58974" checksum="7528026D36AE19DC" modified="2013-05-29" version="1">MSSLAGLRLPPTIQQLLASAPETPSSDETDNPSNAPTPQRARTIYGHLTSLRVTKRTAFLHLSDGSTHEPLQAVLRPREAEGMSVGCSVRLEGELVRSRGSGQEWEFSVKEGGARVVGALDVHTYPLQNKQIRPETLRENAHLRARLPTGISLLRVRSLLAREIHAWFEENDFWNVNVPILTGSDCEGAGEVFSVKPYSMGRDAASVSSPAPSTSENQTSTELASPEPTPPSSTPSARIPSAPKPHSVLHASQFFHRPAYLTVSGQLHLEALTPPLSRVYTLSPCFRAEPSLTHRHLAEFWMLEAEMGWVEPPAGLEGVMDVLEGSVKRVLGSLLSNSALRADVQLLRSSSPSSETDPLAPLLTWSSTPWPRISYTHAISLLQRAKAEGTHFEYDPKVGEGLQSEHEKYLAGLMGPVFVTRYPRGLKPFYMRITEPETSEEGEIETVECFDLLVPHIGELAGGSLRESRLPMLEASLAAHGLSREEYAWYLDLRRWGGVPTGGYGMGWERLVSWVTGIESVRDCIPFPRWAGNMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2E7</accession>
    <name>M5G2E7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_117633</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626934.1">
        <property type="nucleotide sequence ID" value="XM_040770425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2E7"/>
    <dbReference type="STRING" id="1858805.M5G2E7"/>
    <dbReference type="GeneID" id="63685487"/>
    <dbReference type="HOGENOM" id="CLU_008615_2_0_1"/>
    <dbReference type="OMA" id="AVMGWSN"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF27">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="467"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="666" mass="74088" checksum="CB6F4C5F34B41774" modified="2013-05-29" version="1">MSLDKVIEGVTGSTFITHVALSPSARQVIYSIAPKYHSVKQENATSALWISDLSPGSKSRQLTSGDHNDSLPTWSADESGVFFLSDRHKQDDKPGPAAIYAIPTKVGGESYAFTSKENKSAIGQFWLSPDGRYIAYVASREPTAEEQRKEKEKDDPIIFGDKKANAQLWLLTLTTRQVRRLQLGPKDNWHVQWIAWSPDSKDIMVLMKENSSLEFNESTAALLRLSVLPHAAGLVQQVCTLPRLSAGVVLWPSQDEISLLQSFIPDQLSSSITLYFRSSLPEGDIWKQYYGDVEDLVGIQDLHDGKTLAPMVAYGVQTRLDLLTSAGPKKTIWYGDGNVPDEYDIKLTKNGDYVLVAVVSSGTRNEPPELWTGTLASSKLAEGETLKLTEKLSSHNAWTAELPKISVQVIKYKAKDGTEIEGIVTWPKHKERKALPTVLFPHGGPYHRDTPDFDLKSYWAKELPVFAGYLVLCPQYRGSSGRGNRFARSAHAQMGTHDWTDCYDMLQYAIAQGWADKDMLGLAGWSQGGFLTAWGVSQTKDLFKAAVMGAGVCDWGMMAAESDMPEFEADLGGSWPWTENRVDQNGSPIRHIKGIKTPVLILHGEKDARVPTTQGITFHRGLRRVSGHPDNHQLIIYPRELHAFTEKKHAEDVIRRLIGHMDAYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2N4</accession>
    <name>M5G2N4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_14925</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629848.1">
        <property type="nucleotide sequence ID" value="XM_040771061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2N4"/>
    <dbReference type="STRING" id="1858805.M5G2N4"/>
    <dbReference type="GeneID" id="63686123"/>
    <dbReference type="HOGENOM" id="CLU_631651_0_0_1"/>
    <dbReference type="OMA" id="IWENAGR"/>
    <dbReference type="OrthoDB" id="2139606at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051072">
        <property type="term" value="P:4,6-pyruvylated galactose residue biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF351">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE PVG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013175440" description="Hexosyltransferase" evidence="12">
        <location>
            <begin position="16"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="32"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="434" mass="49322" checksum="467CACE69988AEDA" modified="2013-05-29" version="1">MRCVLLLVLFAATFAALWLLMQPKDVDLERYAQDSSRSNAGGREYTPQRPGPPDRSSPRPIEQEQESARSQSPQPPPRIPPAPDAPLPPPLVDTLPPPPTDVVAEPNPNDPKLHKFPPIEKEGPREIDLRWWLDHGATWFLEPIPALVDAPPPSTFKCENTPDFGPLLLIAVFSTAKGWEKRDLIRVLGRQGLGPAIASQVLFRFVVGRTNDKESEDRLQLEIQRYGDILQLEFPENMDEGKTYQFLRWVGERPESERPRFAMKTDDDTFLVLPNLLSVISSLDCSQNIYFGTSWGACITDCYPFYMRGMAYGLSWPLIRWLTTASLSFDDYRSTEDARTGSWFLSLPATEKMYVVDLERRLGDWDGISIPVNSGTVALHAMKSNWLWAKVGLQLMDTWEKEEKEYMYNGERSRKGRELPEGEEGGEEEQDPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2W9</accession>
    <name>M5G2W9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_104461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631470.1">
        <property type="nucleotide sequence ID" value="XM_040767930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2W9"/>
    <dbReference type="STRING" id="1858805.M5G2W9"/>
    <dbReference type="GeneID" id="63682992"/>
    <dbReference type="HOGENOM" id="CLU_041217_9_8_1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001423">
        <property type="entry name" value="Ras family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="211" mass="23865" checksum="12A5B4A8DD54128F" modified="2013-05-29" version="1">MSTSRKRIPEHELVVLGGGGVGKSAITIQYVQSRFEMGWDPTIEDTYRKPAVVDRQEVMLAIIDTAGQEEYRLMRPGYLRSAQGFLLVYDITSRVSFNDVSRFHDEICQAKDLATYPAIILLGNKADLADRRQVKTSEGEELARRMKCGFMECSAKFRENIDEAFHAVVRAVRKYNHKNILDRTADLLAGEDGPERTHYGEEEPKGCCTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G318</accession>
    <name>M5G318_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL30m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_34918</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631515.1">
        <property type="nucleotide sequence ID" value="XM_040774389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G318"/>
    <dbReference type="STRING" id="1858805.M5G318"/>
    <dbReference type="GeneID" id="63689451"/>
    <dbReference type="HOGENOM" id="CLU_131047_0_0_1"/>
    <dbReference type="OMA" id="FYKITQT"/>
    <dbReference type="OrthoDB" id="509901at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000010">
        <property type="entry name" value="Large subunit ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_uL30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="9">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="9291" checksum="E388833EE8168FF6" modified="2013-05-29" version="1" fragment="single">THYRITLMRSALGLQSYARDTLAALGLKKRMQHVYHPFSATTAGQILRVKELVKVENVPASAVKTKQEERQERRPGAGFQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G330</accession>
    <name>M5G330_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_51011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629524.1">
        <property type="nucleotide sequence ID" value="XM_040775023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G330"/>
    <dbReference type="STRING" id="1858805.M5G330"/>
    <dbReference type="GeneID" id="63690085"/>
    <dbReference type="HOGENOM" id="CLU_120161_2_1_1"/>
    <dbReference type="OMA" id="MPLITDF"/>
    <dbReference type="OrthoDB" id="78947at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="123" mass="13798" checksum="2C1037CB3A23D034" modified="2013-05-29" version="1">MPLLYTPYPKVLNSFYGPAPPKRPFLIYYASIDPATGQMWCPDCRAVESTVSDIFDAPDGPTGLIIWVGQRAEWKYPDNQYRKEAGITGVPTIVKLKDGKEVARLVENDILDKDKLASFFKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3H1</accession>
    <name>M5G3H1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CobW-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_106385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630113.1">
        <property type="nucleotide sequence ID" value="XM_040768259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3H1"/>
    <dbReference type="STRING" id="1858805.M5G3H1"/>
    <dbReference type="GeneID" id="63683321"/>
    <dbReference type="HOGENOM" id="CLU_017452_0_1_1"/>
    <dbReference type="OMA" id="GHSHMDP"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="8">
        <location>
            <begin position="30"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="9">
        <location>
            <begin position="324"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="391" mass="42477" checksum="4A5424F85C69D98D" modified="2013-05-29" version="1">MEDGEEIPQLSEALIAQEADPPQDDDDRVPLTIVTGYLGAGKTTLLNYILTENHGRRIAVIMNEFADTADIESRTINVSSEFGLTEEVLELANGCLCCSVKDSGAAAIEKLMKKKGKFDYILLETTGVADPGGLPTPLCPIAVMFWQNEELASDIYLDGVVCVIDSVFGAAQLSERSENCVNDGQRQVACADVVLVNKTDIATASQLNALETIIRGINPTAPQLLTRHGAVNLELILGLNAYEKLPEFPSAFGSIDSCGEESHCNDPSHTHHSHVSYLNEISACIIDLPPLDVNQTKKLDEFIRSLLWDNVLLSPEGFETVDYEILRAKGIFSADGKEYILQGVRNIYDINEVIGIEGVRLNGKLVFIGKGLSGTVALSPSLYRYLGIKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3J1</accession>
    <name>M5G3J1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_50679</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630138.1">
        <property type="nucleotide sequence ID" value="XM_040775002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3J1"/>
    <dbReference type="STRING" id="1858805.M5G3J1"/>
    <dbReference type="GeneID" id="63690064"/>
    <dbReference type="HOGENOM" id="CLU_010119_6_0_1"/>
    <dbReference type="OMA" id="DESFWVM"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="268"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="43719" checksum="88EEC9B18AAB3AE2" modified="2013-05-29" version="1" fragment="single">VMSLPIIPLLPLLPLSEPIERLATAKRLHDACITYGFFYLDLTGFATNEETEELRSLVQQFFDLPLDEKEKIWLGNGDWARGYQKLNENVTRGKPDAHEALDFYAPSPFYPSPPATPGAPEQAGVRPLSGENQWPPDPRFRERFERWVGRMKELGLIVMEAMALGLQLTPSEWASLRRQVENSFWVLRVIGYPPLPSGHDGFSCGSHKDYGCLTFLWADKTQGALQVFLPEPASSASISAHTGLATPTISESEHPRERMDLGPAIENGVRGTWISADPVERCIVCNIGEMWEIWTRGLYRSTLHRVLHQRGNYRIPFFYEPAFDALVSPLTGVDRLLSSLRDSADQQSEAYARVLLAEKTVYKPVIYGEFLMRKVGGNFDKSGDGGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G461</accession>
    <name>M5G461_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydantoinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_96660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625440.1">
        <property type="nucleotide sequence ID" value="XM_040777391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G461"/>
    <dbReference type="GeneID" id="63692453"/>
    <dbReference type="HOGENOM" id="CLU_007154_0_0_1"/>
    <dbReference type="OMA" id="CMGSPEV"/>
    <dbReference type="OrthoDB" id="5404895at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1610.10:FF:000001">
        <property type="entry name" value="Hydantoinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="39"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="237"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="627"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="4">
        <location>
            <begin position="796"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1025" mass="109080" checksum="B2CA5780D2A9A9A8" modified="2013-05-29" version="1">MSIPISSDVIKGAEDIIAHSETAVEHVIHSVEHADVVYRLGVDVGGTNTDAVLLALSEDHKQNAVLSGHKSPTTPEVMDGIVSAVQMVLKDVSDLSKIQALSIGTTHFVNALITRDPRKLHKVAVIRLCGPFSLKCPPFASFPRELRSILKGPVFMLSGGLQIDGREIAPVIPAEVEAACKEIAAANIHAIAISSVYAPIDHTYKQEEAVASIVRRLLPRAHITISKQISNIGLLDRENASILNAALLSYARQTVRGFRRAAALLNLSCPVFITGNDGTLLTCAQAAKFPIRTFSSGPTNSMRGAAWLAQLEMGQEKGEGALVVDIGGTTSDIGMLLPTGFPRQAAAKHHLCGVRLNFSMPDVVSIGLGGGSLVRTHPEDGRVSVGPDSVGYRITSEALVFGGKVLTATDIAVASGRVGDVGDKSLVKHVLKGMVEKAQARIKSMLETTLDSMKTSAADIPVYLVGGGAILAPDHLDGVSRVVKFKNSGVANACGAAIAQVAGTVDTVEEISSRSIPEVRKLIEHRAMDLAIKAGANPDKVSIIESEAIPIAYTAGRCRFYVKAAGEWKGVTGEAEEVGEEDEDGEAGTLVNGAYEPEEPEHVPTAKEIVDYRPRVEQGAWTLSELDLEFIADGAYILGCGGGGSPYQRYLRLREGLRKGAVIRVIDLGSLEDDALIGWGGGLGSPEVADERLSGDEYQEATEELLKFMGITKLAGFAALEIGGGNGMINMILSSSEVFGWPVIDGDFMGRAYPTSWQTTPNVYDDTHKCANLLPSAIASGDGNVMFMTRVKGDRDHDAAFRACCTEMGTSVGCALRPLTAGYCRKAMINNTVSLAWRIGRAVALARKSAQIGNVGNIIVDALGGKETGRVLFSGKIVDVSRSIYKGHTIGRVTIQALADDSEPTDGPVEKYKGTLMIPFKNENLYAEHDPKDGSKPIVLASVPDLIMVIDAQNGAALGTPDYKYGLRVIVLGVTAAPQWTDTERGLEIGDCRAFGYVLRPFPEVKYVPLGKYIQPKSVIEEFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4D9</accession>
    <name>M5G4D9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629989.1">
        <property type="nucleotide sequence ID" value="XM_040771066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4D9"/>
    <dbReference type="GeneID" id="63686128"/>
    <dbReference type="HOGENOM" id="CLU_1098472_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="253" mass="28019" checksum="50326666ECC31A4F" modified="2013-05-29" version="1">MPFLDLDRVDERNINSMLDHEMSTSTDMSDDDGSSSTGSSDDPAPEYEESISDFSSPSPTVRGTSPTPLHKSAHFPGKFPKSARKTARAAHESLRKYKSHPKSEMFDDRVRAWEESDWSDDSPVHSRRASFTKELPVVHRHRKLRPHTRESFRFHSECIKGTTRTLVEYEHSEPGTMGPFATKLFELEAAATTVSWLWGGAGGRVGRAGGPLTRFAELSAAKKVFWNRERIAAFFAGGAAVWLALGSCAISGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G512</accession>
    <name>M5G512_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_56951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G512"/>
    <dbReference type="STRING" id="1858805.M5G512"/>
    <dbReference type="GeneID" id="63690469"/>
    <dbReference type="HOGENOM" id="CLU_000288_7_18_1"/>
    <dbReference type="OMA" id="WMENTDS"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="185" mass="20788" checksum="EA683796CA9FAE0E" modified="2013-05-29" version="1" fragment="single">EIRIWSQLRHDNLLPLLGISTKWGVEELCMVSPWQRNGTAISYLEQNWQDNDEGHDLVLNLILGIAYGLEYLHNQTPPVVHGDIKGNNVLVSDDGNALLADFGLSTVVEDIDPGITSMLYAGSLPWMSPERMDPSRFALDIRTARTPASDMWSFGMTIYEVLLVYQISACFFSYAPARLRKSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5E7</accession>
    <name>M5G5E7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LsdA family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630349.1">
        <property type="nucleotide sequence ID" value="XM_040772203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5E7"/>
    <dbReference type="GeneID" id="63687265"/>
    <dbReference type="HOGENOM" id="CLU_045147_0_0_1"/>
    <dbReference type="OMA" id="WMTYINQ"/>
    <dbReference type="OrthoDB" id="5293813at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067485" description="LsdA family protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="39481" checksum="DB5A308F853E58DA" modified="2013-05-29" version="1">MHGSILTAATIGLAALSASAAPATRDYSAPNSGSSSGSPFPFADGFPTPSPEQLQEIFVEAHGTLSNATPPANISAQGLVNLRLIDFAERIESVYFEEFLANVTNHVPGYEVPSWVDYDYLVNFLTVTQHVEELHNLNAVNALAHFNQTAIEPCTRYNFPVSTFEEAVTLAMTFTSNVFGVLGDVVTLFAENGDAGLTRGVVAAVANEGEQNGFFRYLLGRVPDELPFTTASNRDFAFTALQGFVDPTSCPNIDIIAADLKTFEKVTFIDTPIAKTEDVRLSLAKDKYESGKAYNVVYVNQLNNPVVVPATYVCADDTTVTIEATFPFDEHLMNGLTIASVTDQAGPFANVDAVAAAAIWAPAFVVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5M8</accession>
    <name>M5G5M8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_93479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630903.1">
        <property type="nucleotide sequence ID" value="XM_040777159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5M8"/>
    <dbReference type="STRING" id="1858805.M5G5M8"/>
    <dbReference type="GeneID" id="63692221"/>
    <dbReference type="HOGENOM" id="CLU_2037982_0_0_1"/>
    <dbReference type="OrthoDB" id="5078320at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="11"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="121" mass="13169" checksum="9BA4AB3B304B1C23" modified="2013-05-29" version="1">MRDHRPALFPLFPYEMTYTAGFTRHPGGIPPSPKAALGVKLRTVWNVGALPMPASAASASPSGEQGNGNGNGDGRKGWTRVEERAEIWAPLGLLGYVRRTVVRAHEELMRALEKMLEALCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Z5</accession>
    <name>M5G5Z5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_114545</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
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        <property type="protein sequence ID" value="EJU04144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040769842.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G5Z5"/>
    <dbReference type="GeneID" id="63684904"/>
    <dbReference type="HOGENOM" id="CLU_006108_0_0_1"/>
    <dbReference type="OMA" id="HYMRENV"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
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        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
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        <property type="entry name" value="HISKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="472"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="934"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="170"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="650"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1089"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="988"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU04144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1111" mass="122107" checksum="73051DFC39E9196A" modified="2013-05-29" version="1">MPVGAESTGEHGRDRDRREDGEEGEGLPPPAIASDERTSKKSKSKIRGKTASRKVSGPLGRALTGQRASTSAGGGNKKVTKFEHSEGEKKPFRVRLHEFLKVISTAVSLSDSPIEPTVESTEASSYRANIQRRESDWGIEEDPSAPPAEVNEVVVDAEWDMDKWADMSTTGMSESAGAPAGLENGSAAPGQAHAARALGNPPDARSQAGFTNANSSGIRELWGLTTILRWRLYPRIVRFFDLSFYDAQSEDKYRKDVWFTQKTLAAITACFYLLITILNCTLVGQPFTEFNHIGDIGGGLVFSIPVLFLVLFNVPRMKLRYSWPYQVILMIATWQWAWYNVFDQWNCGFFISRSNNACGQKDFQLTPFYSAALPFLALFALGQNRLFGAIAFIAWEIVSSVLIIPVYNSWTRNTVNSTIWHILLLYVHFTLETAERRSFTLREQLKDQCKATQKAQVNERKESDSKKRFVSYIFHEVRVPLNTALLASQNLIGSGAIKKEEDVEFQALEGSLKMMSKVLNDVLDFNRMDSGRFVTVSKPYCFHGAIRSMLLPLELSAKSRGLTLTMRLDPKIDDIANRTAYGDTEQDVQAVKDGWVLGDEMRLRQLVTNLTSNACKFTSEGGRVHVETRLIMPLSREEVAPLPVLLEVDPETSDTEAVPSSSPAEERQQHPLQLMESITEGANGLNRATQSIHNHHHYHLLGHAGGPALYTPASGRSSIHSGTHGQPHKTGIVVRIEVRDTGVGIKPRDLVDNRLFSPYVQTEIGRFQGGKGTGLGLALVRNIVKLSGGRLGVKSKVGQGSTFWVELALGVGPHAVKARDAVPVRWDRSPAAVPPITSIDFANSPVAPLDTPLMSSLTPPLPNEPSMPLKPLGADVHAFLDPLTEKVVVPPKVQGPEMETPTAVNGTDAHEPPATVTVQQVTEPPQDAQERPLPILVVDDDVLTRRLMSRMLTRIGCTVELAENGLVALDYLIGPGAHTQAVTPRRLPSSTTPSALVTPSSDHTTEPIMIDEHKYAVVFLDNQMPLYSGVQVVEHLRLLGRTTFVVGVTGNALQEDQKEYLEAGVDKILTKPVLEKDLRNVVAIARERHRQLKGGVDPDRGPTGPSNPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G633</accession>
    <name>M5G633_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H1/H5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632605.1">
        <property type="nucleotide sequence ID" value="XM_040771796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G633"/>
    <dbReference type="STRING" id="1858805.M5G633"/>
    <dbReference type="GeneID" id="63686858"/>
    <dbReference type="HOGENOM" id="CLU_052897_3_1_1"/>
    <dbReference type="OMA" id="IKNHYKV"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="5">
        <location>
            <begin position="28"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="150"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="204" mass="21245" checksum="213E0BE427537A58" modified="2013-05-29" version="1">MSATKTKSTKTKAAKPAGGNSASAKTSTHPSFVDMIAECITEHPEEARSGVSRPTIKKFLETKFKIEMNASNVTNISKAITRGHETGKFVLPNGLSGKVKLASKKATEVKKSESKENKPATKPAVTKAKPAVTKKAPVKPAKPAPKKTAKTAAPKKAATTKKPVATKAANPKAKPATKGAAPKKATAAPKKAKATKKTEATKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G652</accession>
    <name>M5G652_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_116497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770215.1"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_028601_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
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    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="320" mass="34753" checksum="2E8C36DE051F0211" modified="2013-05-29" version="1">MAHPDSRVVFVGNIPYGMTEEALIEVFRTVGPVVGFRLVFDRETGKPKGYGFCEFPDHETAMSAVRNLHGYEVQGRPLRVDIAESDPMVEGKTTHQGVINERDVRADSAGHGGRWGPPKNDFANFMNDLPSGVSIPPGKSSLDVISQALASIPHPQLMQTLNQMKAYVGNYPDRARALLVAHPQLSYAFFQAMLMNKIVDPAILERMLKATTQSAAPPLPTPAPPPPQPQMYPPPMQQQPAQYPPPQSYYGMPPPPVPQAVPPPTPAPAAAVAAAPLPADQRAMLMQVLSLSQEQVNALPPTERAAIMQLRSQFAGVLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6C5</accession>
    <name>M5G6C5_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">DUF4210 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630649.1">
        <property type="nucleotide sequence ID" value="XM_040769934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6C5"/>
    <dbReference type="GeneID" id="63684996"/>
    <dbReference type="HOGENOM" id="CLU_566221_0_0_1"/>
    <dbReference type="OrthoDB" id="8625101at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="51749" checksum="CF7139356DA916D4" modified="2013-05-29" version="1">MHAGISLFPLSLLEMCTIRPPTPLPSTPITISSSAPPAYRSPLSLTPTHAHPLPGSWSSSLLSLRIPAPHTLQPKFTARLRLPSKALTIPFNPTFYSLPIPTPTPYVALLPIPLPRLPLPPKGSLQLLLLNPELQPLRAFLVPYDVRHLPPGGRAIVRQTLYAEGVLKYAVQFGVTCDEEGEEMDMPELPSSPLSSSSASSSGASSPLPSPRHPKPHIHLQPNIRIVFSSRVEDSPLKIKNEQECSFPSFPSFPSPSSSPSVPLAPGLDPFIPPVAGIGAGPTVGREIGEPSTKSPSSEPPLPPSAPSPPSPSPLTPPKPRTRLPSTPRPSSPTTTTKFSLPLSPRLGPTLALSTENVQRESVSVGVGVGVGVHIPGEQFGPGRDERRGRTRGRGKGKGKARTRERGRGREEDVDPQLVDTSREETGPLIPISGKRLVQRQFMPHAQMQMQVQADMGMGMDMGWDGRPSRALGKWADEAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6I8</accession>
    <name>M5G6I8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="1">FBP aldolase</shortName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_101463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626280.1">
        <property type="nucleotide sequence ID" value="XM_040767559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6I8"/>
    <dbReference type="STRING" id="1858805.M5G6I8"/>
    <dbReference type="GeneID" id="63682621"/>
    <dbReference type="HOGENOM" id="CLU_040088_4_1_1"/>
    <dbReference type="OMA" id="FCLNAAH"/>
    <dbReference type="OrthoDB" id="2558351at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="296" mass="32563" checksum="3F87A4264835B976" modified="2013-05-29" version="1">MSSTIVTPENNRTLAILKKAKEGNYGVIGMVCYDMDSVMGFRDACEKANTPGIIMLFPISARYGGSQFVAFCRDIAHQAKVPMSLHMDHAVEIADIDFMFDIAEKQGIKLDSIMIDSSRCDTEEEGIAMVKKYVDRANKLGMAIEVELGRLEGGEAGLAAIAEGKQTDPEDADHFIRETGAQILAPSIGNLHGHYINPPNFNQEILKTLKTTYAQSNTYICLHGTDELPDSLFQECVKNGVTKMNMNSWMRDPYMDAYKHALVEGKPLPDVHNIGVKAFADAAERFFPLFGSAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6M2</accession>
    <name>M5G6M2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630749.1">
        <property type="nucleotide sequence ID" value="XM_040768182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6M2"/>
    <dbReference type="STRING" id="1858805.M5G6M2"/>
    <dbReference type="GeneID" id="63683244"/>
    <dbReference type="HOGENOM" id="CLU_021164_0_3_1"/>
    <dbReference type="OMA" id="YEMATIT"/>
    <dbReference type="OrthoDB" id="3543113at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="58651" checksum="759BC70FDC7E170D" modified="2013-05-29" version="1">MTPHPVLSIPELVQEIFQHLESDHTALGRLASVCRDFWQPACEVHWRKVYGVERLLKLLPEEYQVELRECSGWAFRIPSEQDTERVRLYAAFIQEVVIHPGRPPYARGDVLNPRRTLERRGLPMLMLLRPFGPAFPNLVRLHAISETDDSLCTLSRLLSPTLRSLYIHTIQGDNFMVGHFLRAIPVNAPSLQTLEVEALGALSKESEASLLQAARHVSKLSLQAVNPSDAFFRNLAQNNRLRSLVVEFTLARTSPIEVWRPGTFDLLEEFEGEALSAPRTLRLLRAMDMPQLQRLKLTIGTVPRDEVAQEEAHHQPAEPRSVHLIMEKIASFVQLRTLRIVLPNLDDHRLTLSAAIFLPLAACKRLQLFQLIDRSEEEGFDSVFVAWDDQHLMTLLDSWPELHTLHLECSNAQAPRTQLTPGVLLSMAERCPQLRSVRMPIDMTSVGSETCTYPPASNNMYRFTLEASTTIANEVAVTDLIHDLWPLVNVSAWKPIAGPVADDVTRFADLYRRLYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6V7</accession>
    <name>M5G6V7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeobox-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_108097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628449.1">
        <property type="nucleotide sequence ID" value="XM_040768587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6V7"/>
    <dbReference type="STRING" id="1858805.M5G6V7"/>
    <dbReference type="GeneID" id="63683649"/>
    <dbReference type="HOGENOM" id="CLU_568605_0_0_1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF9">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="480" mass="52952" checksum="91918FCEF1A78A14" modified="2013-05-29" version="1">MTTPILPLTPLSDQDEEFGFSQPDDIKRRRRTTPEELSVLEAEYAKNTLPDAKNRVRIGQMTNMSARSVQIWFQNKRQTDKRKAQGLTRRPPRRIPVGSFSHPHSILSLTRDSLGEDEQQRKKRKTLEQAASEAQRRGPTSPSLPGLGLPRNGEEFSAALAIARMQSHSVPFPPRRPLGQLDTNALRPGLSRYASSTLPPSFSRTPEPQAFVRAYSLPSAHFPTAHGQGTKQDPIWERMLSSPQSSPYVAPFGRKRPFEHTPGSHSVPFGARREQESLPEDVTDTSDTSDVEDVGSPLPLEASQGSTSSRQSFATSISDSGCSDIDPDEQTERYRYSQVKYHEPEEAEQPVEAEAEEESIANILDVPDAAGIPDLSFDSVSSQSSDPDLTTSSIDSLPLLLKPHTSGSQEVRLLVSREGEGGPVRLSIRIPGDDWSTAGERHNNRPGGKEEGKEKEKVNAWEKEAAELLCFMASGRGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5G713</accession>
    <name>M5G713_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_114816</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631403.1">
        <property type="nucleotide sequence ID" value="XM_040769883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G713"/>
    <dbReference type="STRING" id="1858805.M5G713"/>
    <dbReference type="GeneID" id="63684945"/>
    <dbReference type="HOGENOM" id="CLU_010189_3_1_1"/>
    <dbReference type="OMA" id="VWIEFRN"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="36"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="255"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="466"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="560"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="616"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="740" mass="83798" checksum="CCC868A08B2859F7" modified="2013-05-29" version="1">MDITGFARSLLPWGPQINQQNQYAGFGALYDPIKLFVIGGTVETSRRLASSAWSHFINSFFLTAHFSEEDFPFDWLMHWLAKQPSWHRSREFETTTCSSSSHALWKTAQFDADAELWGENGQEDDPTGKPSMKVVFRPTLDTTHTIFFKGHWLRVRRSRTSGIETLSISVIARSNTILKALVLQAKREYEQDSEHRIQIYFADSHGSFRWTDSRHKRPMSSIVLEEETKGMLLNDCKDFLRPESEKWYADRGIPYRRGYLLWGVPGSGKTSSIHAMAGELDLDIYVITLSSSWVNDATLASLMARVPARCILLLEDLDAAFTRSTTRSKKDTGVPREQQQQQQQQQQSSLLMDANSMPYSSTHMHHHTLNSHSQSLTDTNTLSLSGLLNSLDGVAASEGRLLFATTNHITRLDPALSRPGRMDVWIEFRNATKWQMESLFMNFFPSAPREAVEVLEREEEALEAERADRLAATSTSASMSASASASTSTSTSTLSGARAQIMSEPALRVLAKKFADTIPADEFSVAALQGYLLKHKTSCVKAVEEAGAWVISERELRERLKREKEEKEREEERLRLKEEEEERKREEKEGWRRKREERLRLVKEQEEMRAEEEEERLERKERERREKEGKEGREKEGKEGKDAKKEGAKKDKDKEEKEKEAAPAPPTAEKEEETLEASMLRDTPASAASTAPTTSTSSSTSTSSVNTATPGGWVRIPASQVQNFVKEEMVAAVLSQAKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7T2</accession>
    <name>M5G7T2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628839.1">
        <property type="nucleotide sequence ID" value="XM_040767434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7T2"/>
    <dbReference type="STRING" id="1858805.M5G7T2"/>
    <dbReference type="GeneID" id="63682496"/>
    <dbReference type="HOGENOM" id="CLU_599943_0_0_1"/>
    <dbReference type="OMA" id="SEMLHIC"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="183"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="456" mass="51775" checksum="46F762156C3250B9" modified="2013-05-29" version="1">MTRHLPGRRLRPRLSKLCLWSQCKTIEHALVQRSARLQSREVKEAVDKTRIALQSILDQSQTWLDNSQLRRSLNAHTIQCQLEEWNGKLNDCMQEFGRTIAFEILNVLFGLGAEASRFYDRMLNQGEAFTALLQAIERNTELMKKKDSLLMDRTEEMPIQCKQPTSQERNMLHASLQSQPQLPKVLPIVGLQGELEVDEHPTQTNTSSDLYRGRLEGRPVAVKRLRDANSNPARVANFMNEAYIWRALNHTNVLPFLGIHLSPTEETGIVTVWIPHGDAMHYINKKPDCYRRAIGIIHGDIRGSNILIDEVVDVTGVWPQARLTDFGLATSADGSPEVVHDATHASEMLHICRWLAPERCNSGPEGLAAPASDVFSFSRTILEITTGSKPFAKEASDFYLMKRLCTNDLWPDRPIGDIAKTIITDEVWELMMQMWASEPSVRSMMNEVQTNLERLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G808</accession>
    <name>M5G808_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LsmAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_14026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631788.1">
        <property type="nucleotide sequence ID" value="XM_040771012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G808"/>
    <dbReference type="STRING" id="1858805.M5G808"/>
    <dbReference type="GeneID" id="63686074"/>
    <dbReference type="HOGENOM" id="CLU_017397_0_0_1"/>
    <dbReference type="OMA" id="APMMMRY"/>
    <dbReference type="OrthoDB" id="2275718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="236"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="836" mass="87055" checksum="17DBEF0033D303D0" modified="2013-05-29" version="1">MAAPRGGGNKRKDGDMGRGGGSRGRGAWGRGGPHMNSPYSPNMTPTGMHSPRGSPAGLNGHPSFSNLAQAASLPPSSIGIGNGSAIPGLSSNIGAKISVSLTNGQRFEGTLSEARMDNQFLLTDAREPNGNSRAKLQVMSHQLMSWSVVEPAPVKPDLGAPAETATDAFRTDGDVSKNAPFKERDLVGPGAWANDTSAGLPPLPNFNDGHGSGDDLTFGVQSAAGWDQFAANEKLFGVRASNFDEHEYTTPLDRSGSDYKNREKRAQKIADEIQNGATSNAHIAEERGLKPDDSGINEEDKYSGVARNPNVYVPPAARRAAAAAAAANGSPSGTTKALSPQPAPATLAAKTSSPPPATTATVSTPPAVTVPTPSPPVEKSKPEEDHEAVTPASKPAPQEKTAPAPAAEKRDTKLTPGTSAAPASASAGDKHVSAAAKVPQVTVENPLVQDFRNFVTAEKERLTTQRKNLAKSEKDKRIADLIRFSTSFKLNKEIPEDLVNIITKDEDKKKQILERSKQDAKATSARTIGPAPAMNASASTRYGGLGIAQAANAVKSPAANAIPPSSSASATTSASSKPVKMADKYAISEIPPFNPGKSKAIPAPKHGLNSGGPTSGKATPAAGSTPSTSPSNDFKLNINASSFRPNATAPSFKPVNGASPSPAPAPSGSPARPPLSKKSPDEPAPSQPNPFFGSNPLKKGSVHIKDDFSPFKHNKVAEASSTPSTWPFTGKRYAALLPPQPTPPPPQQMPAPFEDENQQAQMAQAAYMQQMYAGYRYGGYGPPQPGQPPMPMQGHPNGYMPPPQFMAIYGPMPGVPGGAPPAMYAHPMMSPMGPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G823</accession>
    <name>M5G823_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_67022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628919.1">
        <property type="nucleotide sequence ID" value="XM_040775832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G823"/>
    <dbReference type="STRING" id="1858805.M5G823"/>
    <dbReference type="GeneID" id="63690894"/>
    <dbReference type="HOGENOM" id="CLU_015533_2_1_1"/>
    <dbReference type="OMA" id="NRVEAMQ"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000011">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="163"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="202"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="273"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="319"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="358"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="397"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="514"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="558"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="588" mass="65298" checksum="8971FDF9B9A3ECA2" modified="2013-05-29" version="1">MDSDELYPIAVLIDELKAEDINLRLNAIHRISTIALALGPQRAREELVPFLQESLDDEDEVLLALADELGRGLEDQLGGKAFAYLLLGPLENLATVEETLVREKATESMTKICAVLIPPQHEEYFVPLVKRLSSGEWFTSRTSASALYAPVYPFVSEPTKAELRKGFHQLGADDTPMVRRAAAKHLGPFTKTLAKEHVVTDAIPVYRRLAADDQDSVRLLTVQDLIIIAQLLDSSQVKDQLLPSIRQSVGDKSWRVRYMVGNNFVELAEAVGKEIVQDEMVGAYVQLLKDNEAEVRTAAAGQLPGFSKLLEPEVILTRVLPCVRDLSTDASQHVRAALGKEISGLAPLLGKDATIEQLLPLFLLLLKDEFPDVRLNIISKLEQVNAVIGIDLLSQSLLPAIVELAEDKQWRVRQAIIEYIPLLATQLGVQFFNEQLSNLCMQWLGDTVFSIREAAIVNLKKLTEVFGVDWAKTTIVPKVLAMGNHPNYLFRMTTIFAITTLAPVLNLEVTRDLVLTTVIQLVGDPIPNIRFNVAKALDVISENLSSSPEGRELGRARILPQLETLRNDNDPDVRYFAMRALDKAGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8D9</accession>
    <name>M5G8D9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_76065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631918.1">
        <property type="nucleotide sequence ID" value="XM_040776177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8D9"/>
    <dbReference type="STRING" id="1858805.M5G8D9"/>
    <dbReference type="GeneID" id="63691239"/>
    <dbReference type="HOGENOM" id="CLU_015846_3_0_1"/>
    <dbReference type="OMA" id="GTHEYCD"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="38"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="424" mass="46318" checksum="7A3C3FCF9B9FB806" modified="2013-05-29" version="1">MSSLLEETPLDKALSSALERRRKNGSLRTIAEDPPTETKVDFSSNDYLGLSRNPELRQHFLDSLQKSEYILGSGASRLLDGNSADHIALEKRLAKFYDAPAALLFNSGYDANVGIFSVLPQLGDAIIYDELIHASVHDGMRASRIPKELRIAFEHNNVESVKDILAALLAANPPYLTGERSVFVAVESLYSMDGDFSPLADIVRTVKEFFPAGNGHVIVDEAHTNGLIGPKGRGVVSHLGLEKDVLVRLNTFGKGFGTSGAVVLASPLIRNFLLNYARPVIYTTALAQFNVISISCTLDFLDKGIGEKLAHQMTDISNYCRQSISKCLAQYPSSGIALVPSELVGGIASPIIPIIVTPPLPLALFLQSRGFMVRQIAAPTVPKGLERVRLCVHASNTKQEVDDMIQVLDEWMREHFPETPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8E2</accession>
    <name>M5G8E2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_114753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631319.1">
        <property type="nucleotide sequence ID" value="XM_040769869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8E2"/>
    <dbReference type="STRING" id="1858805.M5G8E2"/>
    <dbReference type="GeneID" id="63684931"/>
    <dbReference type="HOGENOM" id="CLU_1115720_0_0_1"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="193"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="249" mass="26447" checksum="66358766092092D5" modified="2013-05-29" version="1">MSAPLSSSLPYPTSQPPPPPPPSSTQHQAIDPHLQHPMYATDYPRPPHHPHPHATVGAPLSSRYQPYPAGLVHPPPPSARVDGPQPHSNEQSPEDQGQGAGRVLSTSKRAEQNRKAQRAFRERREQHVKQLESRSQLLDAALASADAANRRYEEARAMVEQLRSENTALRTALQAASGGSGSAAAAAIPPASTVQLGKLSPPRESKVNGSSATAAGSPRSQQPVSDARSEGRGGSRGSHDEVAEQMDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8J5</accession>
    <name>M5G8J5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_21910</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629064.1">
        <property type="nucleotide sequence ID" value="XM_040772599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8J5"/>
    <dbReference type="STRING" id="1858805.M5G8J5"/>
    <dbReference type="GeneID" id="63687661"/>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_1"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="OrthoDB" id="15235at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000002">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GFAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="375"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="547"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="697" mass="77741" checksum="4B79C5967DBC39D0" modified="2013-05-29" version="1">MCGIFTYCNFLVEKDRRAICDILVNALQRLEYRGYDSAGIGIDGDHEGEVLLFKQVGKVAALRQLIDSSNVDFTKTFFAQCSIAHTRWATHGQPSPINCHPLRSDKNNEFIVVHNGIVTNSPELRQVLQKRGYVFESETDTEAVAVLCKYIWDSQPSQRLTFTTLVKAVIKELEGSFAFVFKSIHFPNEVVTARRGSPLLIGVKTDKKLKVDFVDVELTQDQEKFGSTAATATPVAPTANGMLAPPTMAQSKIERQQSRAFLSDDGMPQPIEFFIASDASAVIEHTKRVLYLEDDDIAHIAEGELHIHRLRRDDNISAVRAIETLEIELAEIMKGKFDHFMQKEIYEQPESVVNTMRGRVNFDTRKITLGGLRSYLNVIRRCRRIVFCACGTSYHSCIATRAIFEELTEIPVSVELASDFLDRKTPIFRDDVCVFVSQSGETADTILAMRYCLERGALCVGVVNTVGSTISRESHCGIHINAGPEIGVASTKAYTSQYIALIMMAIQLSEDRISLTQRRNQIIDGLHELPGQIQKVLASDHLLQVFAKETLANSRSLLIMGRGFQYATCLEGALKIKEISYMHSEGILAGELKHGPLALIDENMPVIIIMTRDSLYPKVQSALAQVTARKGQPIIICNDDDDSINPKMKTIRVPRTVDCLQGLLNIIPLQLLSYHLAILNGFDVDFPRNLAKSVTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G979</accession>
    <name>M5G979_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0103-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_74503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632213.1">
        <property type="nucleotide sequence ID" value="XM_040776068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G979"/>
    <dbReference type="STRING" id="1858805.M5G979"/>
    <dbReference type="GeneID" id="63691130"/>
    <dbReference type="HOGENOM" id="CLU_038085_0_1_1"/>
    <dbReference type="OMA" id="MHLPYIH"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="327" mass="35869" checksum="7E35B549DA89E4BC" modified="2013-05-29" version="1">MMSGMRRATHANSWYSGARSRLDHQLKGWLSAVEPSSDYSPPIKGCKAIIGPHAGYDYSGPTAAWAYKAIDVTGIKRVFLLGPSHHVYLDGCALTPFATYDTPLGELPVDLATTAELKATGKFSMMSNKTDENEHSIELHLPYVRKTFEGCDIKVVPILVGAINDKKEADFGGILAQYLEQEDTMFVVSSDFCHWGERFDFTFYYPGAPSPTSSIRLEDDSDIPRGGQPIHESISRLDHEAINMLTLPTSTSSAKQAHASLSSYLRRTGNTICGRHPIGVLLGALATLEEDNKHKASLKFVKYAQSSPCKHIEDSSVSYASAYVTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V6</accession>
    <name>M5G9V6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="8">HIU hydrolase</shortName>
            <shortName evidence="8">HIUHase</shortName>
            <ecNumber evidence="8">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_50870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="8"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629556.1">
        <property type="nucleotide sequence ID" value="XM_040775015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V6"/>
    <dbReference type="STRING" id="1858805.M5G9V6"/>
    <dbReference type="GeneID" id="63690077"/>
    <dbReference type="HOGENOM" id="CLU_115536_0_1_1"/>
    <dbReference type="OMA" id="HDGRCDA"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="12841" checksum="FB98E5DC4B75EF55" modified="2013-05-29" version="1">MSKSPITCHVLDSVLGKPGSGIGVRLYQLGSSDDPLALPLLASGKTDADGRCSDLLPPGKLEKGTYKVCFDTGAYFAQAGRECFYPVVEITFFLNNPEEHYHIPLLLSSYTYTTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA85</accession>
    <name>M5GA85_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_46172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632613.1">
        <property type="nucleotide sequence ID" value="XM_040774685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA85"/>
    <dbReference type="STRING" id="1858805.M5GA85"/>
    <dbReference type="GeneID" id="63689747"/>
    <dbReference type="HOGENOM" id="CLU_1726623_0_0_1"/>
    <dbReference type="OMA" id="ASEEHCL"/>
    <dbReference type="OrthoDB" id="3230530at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16977" checksum="FD4269EC04E8A40B" modified="2013-05-29" version="1" fragment="single">MVHLSLVPLKGNASRCFPHSGYLGISPVTFQGLLRTRRDPDDRSPIAATMVIVAVRCYEFRLNKAGTIAKQNVLASEEHCLWVAANANEPIEVVDWDLPFRITLPVSFGGISTVSHQEYKVSWKIEAIIHHTPMFGLGNRLVKALPLNIVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAQ0</accession>
    <name>M5GAQ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase PEP5</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_92166</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS11 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632843.1">
        <property type="nucleotide sequence ID" value="XM_040777047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAQ0"/>
    <dbReference type="STRING" id="1858805.M5GAQ0"/>
    <dbReference type="GeneID" id="63692109"/>
    <dbReference type="HOGENOM" id="CLU_001287_0_0_1"/>
    <dbReference type="OMA" id="ENENECP"/>
    <dbReference type="OrthoDB" id="26184at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033263">
        <property type="term" value="C:CORVET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016528">
        <property type="entry name" value="VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17122">
        <property type="entry name" value="zf-C3H2C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007860">
        <property type="entry name" value="VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="11">
        <location>
            <begin position="438"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="977"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117492" checksum="E1744C5CBC49485B" modified="2013-05-29" version="1">MASVGLAPRQFTFFDSSPVKDAQDLANPPAVFHLPTEIVVIASSTVGILVADIHGVIHVLDRKFERSRGWVAFDGGRVTHMLEKRGILITLGEEAISWGPLLKIWDLVHTDKRTDGPVLLRSVKVGSSNKPFPVSTMALSSTLSHLSIGLGDGTVLLYRNLDQSLFSGSSSLTALPRARTVHEGTPAEPITGLGFRESPAQSQSTEDKGKDAEKSDRGNMYLFIVTTAKVLVYIATGRGSGGSPQEVDEVGCGLGCAVMDKRGRYMVVARDEALYLCGPEGREPSYAYEGPKSFVQSYRSYIIIVSPPFTPSVGASSTALRQLTARADSQSTDVSRVTIFDLENKYIAFTSKFEGGVKDVVCEWGSVFVLCNDGKLFRLEEKSTPAKLDLLYQRSEYALAIRLAQSLGVSESGISDIYRRRGDFLYSKGDYDGAMEQFLHTLSYLQPSYVIRKFLDAQRIHNLTTYLQELHSQGLANSDHTTLLLNTYTKLKDVGKLDAFIRASSVKSKAEDGERGEVKEELPFDLDTAIRVCRQAGYYEHAAYLARKWGRHEDYLRIQIEDAGRYGEALGFLRRLGPEATEHNIARYGRALLSNLPDQTTQLLIELCTGAVNVPQPTSSPELTNGQTGGGASYLSYITNNPAGAILTGLAFSNATPAVAPTITVSQAETAARVGQTQTPTASRPETPPVGAIQTSAVTQEKRPSPRLFFAHFVGHTQQFVRFLEAVALYRWGQSVEPAGSSKPFSDMDVEEQADSTAVWNTLLELYLSQAATFQERNPSISRVLHAKATRLLQQDQTLPYDQTHALMVCSTQDFTEGLVLLWEKMGAYEDILRYYMDQETAGVATTDGSASTKIIQYLDLYGPQDHNLYPLVLRFLTLSPALLSRHTQDVVSILDTIETEKIMPPVGVLQVLSRNHVASVGVIKMWLMKRIAETRGEIEADHHLIESYQKETKEKEQEIKELTDPNHPRVFHVTNCSGCGHPLTLPAVHFMCKHSYHQRCVSDQDPECPNCARAHGLIKDIRRHNARVADQHKEFLADVGENGFSAIAAAFGQGVMSGGKVEETPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB25</accession>
    <name>M5GB25_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Anamorsin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_21455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anamorsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630081.1">
        <property type="nucleotide sequence ID" value="XM_040772406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB25"/>
    <dbReference type="STRING" id="1858805.M5GB25"/>
    <dbReference type="GeneID" id="63687468"/>
    <dbReference type="HOGENOM" id="CLU_098740_0_0_1"/>
    <dbReference type="OMA" id="WARGTAF"/>
    <dbReference type="OrthoDB" id="311633at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anamorsin C-terminal" evidence="11">
        <location>
            <begin position="51"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="18143" checksum="612E595DA0301759" modified="2013-05-29" version="1">MCTSNASAALLPRRQTTNKASKKLLWALSGPSSSHTIIDDSTLLTSADLERPDSCGPSEGPVRKRRACKNCSCGLAESEAEETPALSSGSSSAADSGAEEDVTFTLPKKAEKKPTERERLIALAESIERGELVTSCGNCAMGDAFRCPSCPYLGLPAFTPGQKVEIDFGDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCI3</accession>
    <name>M5GCI3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pkr1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_103170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633119.1">
        <property type="nucleotide sequence ID" value="XM_040767721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCI3"/>
    <dbReference type="STRING" id="1858805.M5GCI3"/>
    <dbReference type="GeneID" id="63682783"/>
    <dbReference type="HOGENOM" id="CLU_068499_2_0_1"/>
    <dbReference type="OMA" id="NTANEPG"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11875" checksum="241C99E48EBA8597" modified="2013-05-29" version="1">MSTTTPENTANEPGDTTNDIVSFFADILTPGSSLRPQFLLALDVVLGFLLFIFLSLLCLTWSLHFLALMAIDIGLWASVKFFVAELARTEEPASSPHVEAEGGESKKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCS9</accession>
    <name>M5GCS9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_38926</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630936.1">
        <property type="nucleotide sequence ID" value="XM_040774452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCS9"/>
    <dbReference type="STRING" id="1858805.M5GCS9"/>
    <dbReference type="GeneID" id="63689514"/>
    <dbReference type="HOGENOM" id="CLU_001570_20_2_1"/>
    <dbReference type="OMA" id="QCRIERI"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="121" mass="13511" checksum="3BC8974E869B5882" modified="2013-05-29" version="1" fragment="single">RWRPAIPSGVPHAATEDFEYGGHMIPKGTLIIDNLWAQTRDELVYSDPETFNLSRFLDTSGQLKPGIPDTHDDNLGFGHGRRICPGRDLALNSLFITFAYLTLAFDMRRGKGADGRDVHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDQ4</accession>
    <name>M5GDQ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20361</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle</location>
            <location evidence="5">COPI-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631611.1">
        <property type="nucleotide sequence ID" value="XM_040771907.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GDQ4"/>
    <dbReference type="GeneID" id="63686969"/>
    <dbReference type="HOGENOM" id="CLU_000691_1_1_1"/>
    <dbReference type="OMA" id="MMDNLFL"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030663">
        <property type="term" value="C:COPI-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="7">
        <location>
            <begin position="830"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="802"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1220"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1694"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1711"/>
            <end position="1721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1933" mass="214176" checksum="5CEB6411820937D1" modified="2013-05-29" version="1">MSGSSDINGMTLAPSKALPELPNGDGHPQVNNQVNVHADDSRPALGPPTPSKGTSAPIVTIDFGSSTPSSEADDRQETASPIQIDPGTSTSSLQDVVLDNPPPEHTIDTVMKEDTPSHSPRPSSPAATYHTYPAAPSSPVVPGASTQTPGRRSSTAMSTISQSSGSVISAVTVSLTSALELISSSREAKRSKDFLTSTQHALELTRSRQATPTRSREIFEPLRLACETRNERLQIASIDCIAKLISHSFFMETTPQIKTTSPLQSPRVPNTPPVIGQNVDQRLPFPDLITHTITACHTESTPSTVSLQIVKALLALVMSPSLLVHHSSLLKAVRTVYNIFLLSSDSESQAVAQGGLTQMVLHVFARCRIPSAINGDASFRSITPNLENADDDETTSPARSTNGSAAASLAGESSQLHAPPSMPDVERSSLQVSSGDTTSEASQGGETNGLETSVPEGISLVNNSTGIGETRPSQLPASAERPVLTLSSFENPNPHDQMGDGDLQTGVPKHVTTNDLFIKDAFLVFRALCKLTMKSLGTDSERDIKSHAMRSKLLSLHLVLTILTAHMPIFVEPSVAIPSGSSSETTPFLQATKQYICLSLSRNAVSPVPQVFELSVEIFWRVMSGMRTRLKKEIEVLLHEIFIPILEMRNSTIKQKSVVMGMFQRLCEDPQAVVELYLNYDCDRTALDNIYEHLMNIISRHSSTYLTILQGKSADLNSTSIKQAKFGVDVTSIPPSYSTAAVSAADDASTSVSESTLKLQSLECLVAVLRSLATWGTTTNGGISLEIRQNGSDDRLINASHPETAGLATPSLERLPDRISTPDSSDDPEKFESAKQRKTTLLEGIRRFNFKPKRGIQFLIENGFIRSKNPKDVAAFLLHADGLSKTMVGEYLGEGDDENVAIMHAFVDMLDFTNLPFVDALRLFLQSFRLPGEAQKIDRFMLKFAERYIAGNVHTSFANADTAYVLSYSTILLNTDAHNPQVKVRMSKADFIRNNRGINDGSDLPEEVLSPIYDEIVSNEIRMKDEAESSAGQVIPSQGLVNALANVGRDLQREAYVMQSLGMANRTEALFRNLSRTQRRGTPRPSEQFFSASHHVHVRPMFEVAWMSFLAGISGPMQDTDDLDVVLLCLEGFKHAIRIACFFDLDLERNAFMTTLAKFTFLNNLGEMKVKHMEAIKLLLELSTSDGVKDNLKGTWHEILSCVSQLERLQFISDGNEGVSATRKSQTQRKSQLHRSKKPVEELAHASRSTQITVSADMVFSWSEKLSGAAILDFVKALCDVSTEEIQSSGMSERPRLFSLQKLVEISYYNMNRIRIEWSGLWMILGEHFNQVCCHNNPSVAIFALDALRQLAKRFLEKEELPHFKFQKDFLKPFEYTMIHNSNPDVRELVLQCLHRLIQGQVENMRSGWRTMFGVFSAASKVPNLGVANYAFEIVTQLYNDQFAAIVRYGSFADLTVCLTDFSKVSKFQKISLLSINMLRSVIPTMLDTPDCSLKSGPDGGTNFATIDDPMIRFWFPVLFSFYDIIMNGEDLEVRRLALDSLFDALRAYGSTFSAEFWDMVCREILFPIFSVLRSQDLSRFSTQEDMSVWLSTTMIQALRELINLYTHYFETLERTLDGLLELLVVCICQENDTLARIGTSCFQQLLEQNVHKLSPQRWERVITTFVKLFKTTTPYQLLDESLRTDLEDVNVGEVTGAESPGPNIIPAPLSSDSGPRQNDISAAQRKQTFKQIIVKCVLQLLLIETTHELLQNDEVYSTIPPEHLLRLMAVLDQSYQFARDFNADEELRKGLWKAGFMKHLPNLLKQESSSAATLVKVLQRMYEDERVDREGGRGRISERLIPLCLGILKDFNGLRAAKQSKSIVTWSPIIAEVLQGFSNLADGDFDLYLSALYPLATDLLARDLTPEVREALRRVFLRVGIAKGITAEVHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEG0</accession>
    <name>M5GEG0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">DACRYDRAFT_21472</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630107.1">
        <property type="nucleotide sequence ID" value="XM_040772413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEG0"/>
    <dbReference type="STRING" id="1858805.M5GEG0"/>
    <dbReference type="GeneID" id="63687475"/>
    <dbReference type="HOGENOM" id="CLU_000288_54_0_1"/>
    <dbReference type="OMA" id="QCTHLVP"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08689">
        <property type="entry name" value="C2_fungal_Pkc1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11620">
        <property type="entry name" value="HR1_PKC-like_2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000101">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000014">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000034">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037778">
        <property type="entry name" value="C2_fungal_PKC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037312">
        <property type="entry name" value="PKC-like_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="157"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="18">
        <location>
            <begin position="239"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="468"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="536"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="791"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="1051"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="68"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="604"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="650"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="758"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="673"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="820"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EJU03213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1118" mass="125031" checksum="47CB23CD08520D21" modified="2013-05-29" version="1">MAQELDQKIQEVYKRIQMERKIMDGSHQLLQATSNPAVRNRADTQLRDAQRSLSYFEDTLRELQAKKLQLQQQSQRPPRGTSMPTNTGQLASLQDSTPSSGFAQRPGASRDRALPAPPSDIGPEGRQNGISDLQNGGIDSTDYVPKPKAYSNLDLLRADTPYTTAKISRMLHQLEFKLHVEKQYQRAIDNMVTLYKADGDKKSRQDAEAKQVESNRKIQLLQQAVKRYKNLHIYDDPAENEEDEFGVDGQRKEGLRKPLSGKLRITIKAARELDHISLPAKRSSKAVASETTVVVKIEGTPRAQTHPSRNDRWNEEFEISIDKANEVEIAVYDRQGNDYPIPVGLLWLRVSDISEALRRRRVGNETGQGWVTAATMPNDASNSVTPPISSEYNSLLPGSYGGPGGGTNATAYGTADGIDAWFAVEPVGAIALHLEFLKENVRKRPADVGLGRQGAVRKRKEEVHEMNGHKFVLKQFYQIILCAFCNEFLLNAAGYQCEDCRYTCHKRCYSKVVTKCISKSNAETEGDEEKINHRIPHRFETITNIGANWCCHCGYMLPLGRKNARRCTECDITCHATCAHLVPDFCGMSMETANALLASLRDIKSHQQRPRPGPQPPRTPTTPTAITCSPQARPETLEGTFDRLNVAAERGPNDVYGRPPGAMPPYAPDRLPPSTQSYQQAPPSPVSQRQTPTRPSTGEIPAQVSRPGTIPQTKYPAPGEGSPSVSAPLYTAKPIASAAPGPTESAVSKPYPLSGVATPTIPGMTSGPGVSLQAPPQRPDKRKRKVGLDDFNFLAVLGKGNFGKVMLAEEKRSNALYAIKVLKKEFIIDNDEVESTRSEKRVYLTAAKERHPFLLGLHSCFQTETRIYFVMEYISGGDLMLHIQRKQFSLRQAKFYACEVLLALEYLHANGIIYRDLKLDNILLTLDGHIKVADYGLCKEEMWYGETTSTFCGTPEFMAPEILLEQRYGRAVDWWAFGVLTYEMLLGQSPFRGDDEDEIFDAILEDEPLYPITMPRDAVSILQKLLTRDPGRRLGSGANDAEEVKKHPFFKDVNWDEVFHKRIPPPYYPSITSAHDTSNFDQEFTREQPTLTPVHGQLSNRDQQEFQGFSWIAPWADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFD8</accession>
    <name>M5GFD8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Voltage-gated potassium channel beta-2 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_114491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630967.1">
        <property type="nucleotide sequence ID" value="XM_040769828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFD8"/>
    <dbReference type="STRING" id="1858805.M5GFD8"/>
    <dbReference type="GeneID" id="63684890"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="CQPYYNL"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="32"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="357" mass="40446" checksum="6439EE11701ABC9D" modified="2013-05-29" version="1">MANFQASYEYQPKGMIFRNLGSSGLRVPVFSLGGWLTYGGTVKGDPVKEVMKAAFEAGINMFDTAEGYEAGECEREMGRVIKECGWRRTDLIISTKIFFGVRRQGPNDKGLSRKHLIEGLTESLERLRMDYVDIVFAHRPDVTVPMEEVVRAFNYLINTGKAFYWGTSEWSAAQIEEAFAIANKLKLIPPIADQCQYNAFHRSRFEAEYDSLYRKYNYGTTVFSALASGILTGKYNHGIPKDSRFTTNADFFKNTIEQLRKPEGQQKIQKVRELTKIVKEYFNATPGQLALAWVAKNPNTSTIILGASRPEQAYDNLKALEILPKLTNEIYEQINRILDNAPPAEPHYGRGTRHALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFG0</accession>
    <name>M5GFG0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_87403</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631007.1">
        <property type="nucleotide sequence ID" value="XM_040776807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFG0"/>
    <dbReference type="STRING" id="1858805.M5GFG0"/>
    <dbReference type="GeneID" id="63691869"/>
    <dbReference type="HOGENOM" id="CLU_011639_1_0_1"/>
    <dbReference type="OMA" id="DEFELWG"/>
    <dbReference type="OrthoDB" id="296793at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="130"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="294"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="818" mass="93001" checksum="57525B7BB00E983F" modified="2013-05-29" version="1">MGWPSLQRRAPAIPSLTLQKPQQITVEEWENKAPLDERERRSVARLKEICENRPFPAKFASETAVSTRPGTPSRQSPYPAGSPHTPAGAPTSRLHPSAYPPFTTAVALNDYLDVINASIEHEQEAHYRSFLHELDEYIDTCNAINERLDSVEHDVQSMLESWRSVESGSTRIQGASEQMLEERDRLVAISEELSFRLEYFQQLEEATRMLNHPGESLVLQTEFLHMIERVDVCFDYLTTHRHFKEAELYLLRFQQCMTRAMTLIKMYFVGMLKALQTDVQTRLANKDISDIAQHHLLYSRFQSVSAQVVPLLRELERHAALHPEDVSSLLTECHTAYFTVRRGLLVGRIIEEIKILDPERSELVELTRAGCSYLKLVCTNEFDLFRLFFTSGEDAIYRYLEGLCDYLYDDLRPRILHEPRLLTLCSVCTVIQALMVMDVEVPPTGASIEMHTEPPAEDPLARLQVSHLLQMVLQDAQTRLLFKAQSVLQSDIGYYAPKPGDLEYPGKLQNVQNPEKEQSQSIVPQTEQDSDALFRLPSQAVQDTWYPTLSKTIWILALLHDFVKPAIFQDIAQEAIGLCRHSLSAASDLIAGQSEAGQLDALLFFVQHLLVLKEVVASLELDYVRTERGIWVDGVTETLGTLLRSTSSLLRPTAIFSRRAQSNIVMSDAADPKIAIDSDLKRVCEDIISICTDEAIAPIRAFRERLANHTRTKAGTASAAQQEWGKPAALLEIDAKFKEDCSSVIRKWIDHLELYLQDPATVAVLVPPMQARIVEEYRVWRDLVRDEYEWGTADKLMREPQVWDFVREATGEPYGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFY6</accession>
    <name>M5GFY6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4112 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_47767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631457.1">
        <property type="nucleotide sequence ID" value="XM_040774781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFY6"/>
    <dbReference type="STRING" id="1858805.M5GFY6"/>
    <dbReference type="GeneID" id="63689843"/>
    <dbReference type="HOGENOM" id="CLU_067862_3_1_1"/>
    <dbReference type="OMA" id="CNFCGIR"/>
    <dbReference type="OrthoDB" id="2103474at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19902" checksum="7E12886656CB55B4" modified="2013-05-29" version="1">MAEELARRYGVGLFKKHIAQYEPSDPMYETYVDKKGRTKRRRRAVPPGLSARDTKILKSVQRRAHYLDKGMNLCGFRVGWTFWIGLVPGAGDVADAALNYFLVVKKARQAEIPDWLVTRMLINNAISAGIGLVPLVGDIALATWKANSRNAALLEEFLRVRGLHFIEEQAHSEVRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD9</accession>
    <name>M5GGD9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_46045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632212.1">
        <property type="nucleotide sequence ID" value="XM_040774680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD9"/>
    <dbReference type="STRING" id="1858805.M5GGD9"/>
    <dbReference type="GeneID" id="63689742"/>
    <dbReference type="HOGENOM" id="CLU_050877_0_0_1"/>
    <dbReference type="OMA" id="SWSRMTV"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="107"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="439" mass="49694" checksum="9B5D1625FA44A855" modified="2013-05-29" version="1">MPTLEASLPAPRLRIKVMEYEEKGIPLVVRGFHKLPGWEDALFTPEWLLEHSTGLNETISVRNVYDKRDSEMPLPEFIERCKNITDIVPGGTQKERYYGKDGICPEQWEAWLSSSGVVPKQILPFSGDDAFRFIPKQCRAETLMTYFGVGGTGTPCHKDLCASVGQNLMVHTENEGSAVWYMTLREDATSVSQYFRSLGQEVDLETHVASELELKVAPFKVYMHRQERGDLICVPQKSCHQVINEGGISIKLSWSRMILSSLVMAYESELPIYHRVCRPEIYSVKHLIHGAVMSGTKSLSEALSESDGDVTSRVCAMRDRLKPLVNAYTEIIVEGWDPQRKGEPQTWDPDGQTRISCDFCGAEIFQSYFECRECDQEKKESVSICSTCYVEGRSCVCDFMEPVTVQPFSLLLSVRNKAVDVLNRCLTEEEQLIPDYTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGK5</accession>
    <name>M5GGK5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-serine dehydratase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632542.1">
        <property type="nucleotide sequence ID" value="XM_040767880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGK5"/>
    <dbReference type="STRING" id="1858805.M5GGK5"/>
    <dbReference type="GeneID" id="63682942"/>
    <dbReference type="HOGENOM" id="CLU_1578476_0_0_1"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="1">
        <location>
            <begin position="48"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="169" mass="18519" checksum="507286B8D430BB79" modified="2013-05-29" version="1">MLNCALPRRRASGTHLALKGKLEIHAGNYPCLDLQQLATHLICEQQIAATVFTTVVSSYPDRDGGEGMCDAGALAMSKDRGPNPGFGDVVTPGWENWRLGRISQEHGGLTRAEGKQGKELERWAQCSRSWGSIRASRAHAFPGIMSLIRVKGMERLWLMFGCRGEPGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGZ5</accession>
    <name>M5GGZ5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633242.1">
        <property type="nucleotide sequence ID" value="XM_040769555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGZ5"/>
    <dbReference type="STRING" id="1858805.M5GGZ5"/>
    <dbReference type="GeneID" id="63684617"/>
    <dbReference type="HOGENOM" id="CLU_075836_0_0_1"/>
    <dbReference type="OMA" id="HLQWDEE"/>
    <dbReference type="OrthoDB" id="551302at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="29121" checksum="840E089AFDB77E58" modified="2013-05-29" version="1">MSLRSPPPPPPPPPPPPPPPTDIPPELHSPPSTASAPKPKGILKNALPPLQTLPANYTGAHLSWDEENIAATDLSNETFMKITEPKTPYVRYNAELDEVEGLSYIPDFSLTQRSPYSSVPPSPHPNQSQTQTQPQNQNQFSSPSPRTSFGQPGTAPNRPSVSASSGSSRSASFSLPGEEGIRLTPGEGTWGEVEEDEPMDEEATKKHAAFVKARGRHYSHEGEAMKMARFLPEEEDEEPREEPEGEEYPEAEASPLPNGADAGSVSAGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH04</accession>
    <name>M5GH04_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_92414</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633287.1">
        <property type="nucleotide sequence ID" value="XM_040777071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH04"/>
    <dbReference type="STRING" id="1858805.M5GH04"/>
    <dbReference type="GeneID" id="63692133"/>
    <dbReference type="HOGENOM" id="CLU_020279_2_0_1"/>
    <dbReference type="OMA" id="FPGRCAN"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000006">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000004">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="17">
        <location>
            <begin position="299"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU06393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="661" mass="74339" checksum="8EB6DBD4E0A664DD" modified="2013-05-29" version="1">MPTVAVDKADLFERLGRNYTTEEFDHLCFEFGIELDEDTTEEVEENIKKGLPAERPQLKIEVGANRYDLLCLEGISRALRIFLQLQKPPVYKYRKFGPGEKMITATVAPDCARVRPFFAGAVLRNLHFTQRSYDSFIDLQDKLHQNICRRRSLVAIGTHDLDTIVAPFSYEALPQNEIKFVPLNKSQAYTCEELMELYKSDKHLSRYLHITKDLPVHPIIYDTKRQVLSMPPIINSEHSKITLNTRNVFIDVTATDETKLNIVVNMVATMFSEYCSEPFTIEPVQIIYPDERTKITPELTPHKMVAHASYINACTGLSITAKKAATLIERMSLHTSLSPNSSDEILVDVPATRPDILHECDIMEDAAVAYGFNNLKKTFPSTSTVAQPLAIGRLCDIVRRECAQAGWIEVLPLILCSHDENFAWMNRKDDGKTAVRLANPKTLEYQVIRTSLLPGILKTVRENKAHALPIRVFETSDVVIQDLSRESQTRNIRNMGAVWCNKTAGFEIVHGLLDRIMAILEIPRIHEKESTDFGYYIKETQNPTFFLGRAATIHYRPKPASSHQAVNSSMAAALAEPAVSKGGTSVPLYTLHAQQANSLSTVDTLKTALSSIAPSVNDIQLGMLGILHPTVLQKFEIDFPCSALELNLEPFKKESLNVWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN17</accession>
    <name>M5FN17_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623563.1">
        <property type="nucleotide sequence ID" value="XM_040769425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN17"/>
    <dbReference type="STRING" id="1858805.M5FN17"/>
    <dbReference type="GeneID" id="63684487"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="LPNFNWG"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="36207" checksum="6210F50C17E8AF2C" modified="2013-05-29" version="1">MPALPPGSLIVVVGITGYIACYAGLEALRAGFRIRGTVRDTQRAAALRVAYEKFGVDASPENLELVTFDDLGSEAQLEVAFADADGVINLTMPEFDSEDDYVSRMIDGMMLPLRVAARVPSIKRYVMTSTLAAADPQLVGGAPTAEPITEHAWNDEAVQLYNTLRAAGEKNQWVEYCAGKTLGEKAAWEFIEKNKPTWDLVTIFPACTWGPVMFGPARTTAQILAGLLEGDPTLCYMRPYTYVDVRDCGKLHAIAIAEESFGGKRTIAAAGPTNIKEVVDKLKKSFPSAKLPGGPSLEVPASKWNIDNAVATRALDNEWISVEDAVVETAKSVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN71</accession>
    <name>M5FN71_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin-binding monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_97375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623833.1">
        <property type="nucleotide sequence ID" value="XM_040777449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN71"/>
    <dbReference type="STRING" id="1858805.M5FN71"/>
    <dbReference type="GeneID" id="63692511"/>
    <dbReference type="HOGENOM" id="CLU_006937_6_1_1"/>
    <dbReference type="OMA" id="YQATFES"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="589" mass="66163" checksum="35D2C7FC327ECBD3" modified="2013-05-29" version="1" fragment="single">MSSAWQQPPHDPSHPPDFGHAPYQYKVPPKVPIVERPIDDYRKIKVIVIGAGFSGLCAAIRLPQRIPNVEFVVYEKNPAVGGTWYESHYPGLACDIPSHTYQLTFEPKTDWSAFYSPGPEIRSYLEGVTEKYKLAPHIKLDHKITRAEWNKDDGKWMISGEIADTNEPWSDTADAVISGMGFLNKWKYPNIPGLKDFKGKMCHTGHWTLESAGEAWKDRRVAVVGVGSSAIQVVPALQPWSKQVDNYVRGKTWIAAPIAAPILDSLTGSAKGNHFFTDEEKAKFASDPEAYNDFRLKLEDELNAVHGATIRNSEMQNGARQAFKELMVRKLSKKPEIAEHLIPGFPVACRRLTPGPGYLESLVEDNVGFVTSDIKRITETGIETVDGQHREYDVIVMATGYDTTHVPAFPIIANGENVQDAWREMPITYMSVCSGNVPNWFNSLGPNSAVGSGSLLVLAEKELEYAFKAISKIQREGIKSMTPKASAVDAWNNYMDAYFPRTVYSEKCRSWYKGGKEEGRVTGLWPGSCLHAVFALENPRWEDFDYEFLPDHKGILSWLGNGWTTMEYEEKVGHRAFYLEHIDYPPVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNN9</accession>
    <name>M5FNN9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication factor Cdt1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_25082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624643.1">
        <property type="nucleotide sequence ID" value="XM_040774000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNN9"/>
    <dbReference type="GeneID" id="63689062"/>
    <dbReference type="HOGENOM" id="CLU_014094_0_0_1"/>
    <dbReference type="OrthoDB" id="3366139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Cdt1 C-terminal" evidence="4">
        <location>
            <begin position="372"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="476"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="57764" checksum="4C5C8B13648E60FD" modified="2013-05-29" version="1">MTTPLKRRRLQRVSSTGSFTLSDPSDEEIVTAKKVRQAPPSPRATPVKPVTLSSPGAKKQSNRSSTLPPTLSHLLQLHTALESLLALKLGSSALAPSAHPTRIDTLTIINICTSAELERAAGRRCAPAEIARLCWIYEAGVAPVAVETRPETPVNSKEQNDNPFVTPTKSRRSELEWMRGGTGITLSPMRVLEKDFGKRRTVYAFGIEVDASASGGKTGLDVASRWLSEKPPRVRLIEKRIRDWWKKNTVNPLPPFPSSTLPPLIQPANLPTPSSTRTRSLASTPVKKGALSSNTPTPTRVHKALMSDNPFMTPPETPTKIRGLPSSLPVTPAKSDGRITPTSGSSVKDRKNALFERLAAKAGTPRGTILFRDEQTEEERAFTPDELKRRSALSRLGGVAEGIYMMFSSTGGDLATPATRRRRAVPMDEAIQILVKSSKVAISEAEAQLSIKMLTELCPFFVRILVIDRAEWLEAPSSSSLATPPSPGSVAVAEMSKRSPGGSPRRVGRNEDGGLRRVRERIRRELDGPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPG2</accession>
    <name>M5FPG2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_112018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623951.1">
        <property type="nucleotide sequence ID" value="XM_040769330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPG2"/>
    <dbReference type="STRING" id="1858805.M5FPG2"/>
    <dbReference type="ESTHER" id="dacsp-m5fpg2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="63684392"/>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OMA" id="CFEQPPR"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140978" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="532" mass="57927" checksum="18A8639CC9EA489C" modified="2013-05-29" version="1">MVQVSLLLLVVVLAKSTLAVYPLVDLGYSKYLGTAQTNGVTSWWGMRFAAPPLGNLRFRAPEDPVYNGTVQTANTHGPLCLATGGLPNDTTTSEDCLFLDVYAPSNATVKSKLPVFLWIQGGGFNANSNANYRGDGMILASGMDIVVVNFNYRVSLYGFLASEEVVANGNTNVGLLDQRFAVEWFGGDPGHVTIGGCSAGGASITFQLTAYGGRNDGLFHAAAAESASVFTILTVAQSQYQYDALVARIGCSNATDSLACLRAVPATTLQANNYYIPYPGLGPNASSPLFMYDAVIDGDFIQDFSQRQFAEGKFVQVPVIYGDDTNGGTDFAPKNTTDYAQMDQFLIDNYPTMTPDQITAFNYMYPEDMEFFNGTGAFWRTTSNAYGELAYLCPGMFVSTSYAAYSTFGSWNYRYNVEDPTQMAEGYGVPHTVETAAIWGPAYVSGTPPASYWPNGTNADIVPVLQGYWTSFIRSYSPNTFRYPGSPVWQEWVPSMQNRLMIMTNATAMETVDINEQARCAYITANSVSWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ60</accession>
    <name>M5FQ60_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HSP20-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625883.1">
        <property type="nucleotide sequence ID" value="XM_040773540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ60"/>
    <dbReference type="STRING" id="1858805.M5FQ60"/>
    <dbReference type="GeneID" id="63688602"/>
    <dbReference type="HOGENOM" id="CLU_078883_0_0_1"/>
    <dbReference type="OMA" id="EEGPYWP"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="228" mass="24403" checksum="071F771F4EAEC4C9" modified="2013-05-29" version="1">MSTHPQVTWAQRSSATVPEKNILYVTVDLPDIVPDTLQLDFKEDSISFKATAGNAARGLPEKGYAFTLDLYASIVPEETKKVLSSRHLALQLRKKEVQAEYWPRLTKIKTPWLKTDFTKWVDEEEQDGVTEPDDLGGMGDMGMGDMSGMPGMGGMGGMPGMGGMGGMPGGSDFNFEEMMAKINAGSPGAAPGGADEDDEDDDDDDVPPPLEAAEPSSSKDQEGEAGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQC8</accession>
    <name>M5FQC8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625978.1">
        <property type="nucleotide sequence ID" value="XM_040773570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQC8"/>
    <dbReference type="STRING" id="1858805.M5FQC8"/>
    <dbReference type="GeneID" id="63688632"/>
    <dbReference type="HOGENOM" id="CLU_425790_0_0_1"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="70563" checksum="8F0185D80F7D5D5C" modified="2013-05-29" version="1">MALLLTPHPEPANSISCPRPRSHMPGALAQTSYDPARYVLLLTPPDQPRQLTKRESTEVEPRLAAHLAALVTAGLGEQEKRYPEKMQLPVHMLNGRPSSSGHVRQKTSLSLQVPATSQRPASQPVVAGPSNHPLMAYRNAAASSSQMSLYNSPVSPPTESFNPRPYSNGAGPSPIEYEPPVVEEAPPPQHRVHAISNAMQAMTVSHPTSVPIDSRRLSISSTDRHVVSLPASAKLTFWDTPFPDKATKDNTSLARNTCSMMCYIWYSDSIGLPLTEAEQQQQDSQDSLPIEEEIRTRMQFNPSKDFITFMQGILSTTQLSRSVVVLALYYVYKLRQSASVPASRGSETRLAVAALMLANKYVDDNTYTNRTWSDVSHLPLTDINKAEEEFLNGINHNLCVSRPTYDAWLKTLKSLAHARDQEHAAYLHKRSVLRPRTMQIRKLVRARSSSPLKPRLPQPDVTLVSAGFLPTEQTDAFYSSPASPILNASPLVKDEPLSPALPSTGAKRSVNVAFSPESVHVAPPAKRGTAWTAMSNGHRFDPPLQLPPLVIPGEPTLHREPTQHTLQPLRVPAYSRHPSAHRNTIPAPTAQSVIPDVPFTYCMPVPSIPPIVPPVIPPGPAAQHMQPPQVQHANGTYVPCPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQD3</accession>
    <name>M5FQD3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">20S proteasome subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_25016</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624546.1">
        <property type="nucleotide sequence ID" value="XM_040773966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQD3"/>
    <dbReference type="STRING" id="1858805.M5FQD3"/>
    <dbReference type="GeneID" id="63689028"/>
    <dbReference type="HOGENOM" id="CLU_035750_4_1_1"/>
    <dbReference type="OMA" id="ATCIGKD"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000028">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="27103" checksum="D03DAD146127B9EC" modified="2013-05-29" version="1">MAEGGRSGGAYSFSLTTFNPSGKLVQIEHALAAVSQGTTSLGIKASNGIVIATEKKASSILIDDSMIEKVSVICPNIGIVYSGMGPDFRVLVGKARKSAQAYWKMYGEYPPAKVLAQEIATVMQEATQSGGVRPYGVSLLVAGWDDHRGPSLYQIDPSGSFWAWKASAIGKNMVNAKTFLEKRYHDDISLEDAIHTALLTLKEGFEGQMTEKTLEIGVITVPEGNTLTMKDGRPLPTFRKLTHEEIKDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR08</accession>
    <name>M5FR08_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624157.1">
        <property type="nucleotide sequence ID" value="XM_040775552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR08"/>
    <dbReference type="STRING" id="1858805.M5FR08"/>
    <dbReference type="GeneID" id="63690614"/>
    <dbReference type="HOGENOM" id="CLU_025989_0_0_1"/>
    <dbReference type="OMA" id="LGWNEPK"/>
    <dbReference type="OrthoDB" id="1708389at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021709">
        <property type="entry name" value="DUF3292"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694">
        <property type="entry name" value="CONSERVED EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694:SF1">
        <property type="entry name" value="PEROXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11696">
        <property type="entry name" value="DUF3292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="642" mass="70078" checksum="AE0C06EDD3C91AA2" modified="2013-05-29" version="1">MPDHLDGLPHTDQVAITQVSEKSARDPGIKDVGWNERPEEVPQPVVGGVTNDTLWMLVRRFDKQMYHVKAVPESKIVGPLDLQVAEEEEFSPDKLRANLERLYVSVIISIMAFIKHIMRLRSWSEPRRTGLWLAAYIAAWGTNLVLPSFFTLLLVLILFPPSRAALFPPAPLALISSKTGNLQTPRAGTLGTADTLTGAPENHAGEAAEQEATNFVNGFASLAVGTALGKHPDGDADVHTEPGEQAIDKSLPDPSDLGTTALEAKQTAGGSGIDGRQEKDKTKQPMEAAVWAKARPTMRALTALADTWEMFANALSPVPPFNHLARWKLAGAVVPLMVLTALTNNELLNRAVGAGVGIAFFGQPLFDHGLAYLNERHPGWQRMLDLRNSLLQGVPTNAQLTLTLLRIGEANKQPLPPPPVTREPPEEPEEPLVKHEELPSDLQNAEIEETPSDENVDVPQGAGHKTPKKHKLITKLGGLLKGTTKAGVSGILVADRIKANLGSEHAKQRLGIIPPSDAQDLVDGPSVFEARVHGRPGHVIISTTATTPCISWIPAGNKRSKATGEWEAEFSVLLSDIQELRKVGGLGWKGKLVVGWAYEREVYDALELTDTKGKVWTFTAMKRRDELFNRLLAMVKHKWEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR72</accession>
    <name>M5FR72_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_111930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624287.1">
        <property type="nucleotide sequence ID" value="XM_040769311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR72"/>
    <dbReference type="GeneID" id="63684373"/>
    <dbReference type="HOGENOM" id="CLU_1142570_0_0_1"/>
    <dbReference type="OrthoDB" id="2502792at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="243" mass="27964" checksum="75D3885D2C677712" modified="2013-05-29" version="1">MNNFRDYVDDPRLMLQHLPPPLQTAAEYAPHVIRWLINYLISPIIYHFQNLGYQLTRLTSTPPSELQTQDIFFPLLSLILIYFAVTSALHTARYAFHMGSWLLKWGTLIGIVAVAWAWLSADPSAVGHEQHGYGYSWGRGTSTIPSLVDRVWKMVNGEQQREWLVKELPEVDWSGWVPEWVALDGGFHWIEVIDGLGAENVRKAAEEWWKEQMDSKPSGSKGKKKTSSWRLTKEKKQKTSTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR84</accession>
    <name>M5FR84_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624312.1">
        <property type="nucleotide sequence ID" value="XM_040771388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR84"/>
    <dbReference type="GeneID" id="63686450"/>
    <dbReference type="HOGENOM" id="CLU_1434406_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="20508" checksum="5088A56502D1D47C" modified="2013-05-29" version="1">MVTTANPSASESSDGVVLWSPTLSSPMVVAHSLGSPATLAVSISDSRPTVQLTSPVDSLSPYAMILVLNLGAMSMFWQVLPFMSMFDATIILKQKLQMEKMHTKDLKQNDLVLIKSNISCFQDCQIADDFLLPSKSNSHTGCSSTSKTDSKWRATYLLKAVNMLVPAAFDADDVSDLEELRSDDAVISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR97</accession>
    <name>M5FR97_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_96744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625046.1">
        <property type="nucleotide sequence ID" value="XM_040777398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR97"/>
    <dbReference type="STRING" id="1858805.M5FR97"/>
    <dbReference type="GeneID" id="63692460"/>
    <dbReference type="HOGENOM" id="CLU_006586_8_1_1"/>
    <dbReference type="OMA" id="HNGNYGL"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140962" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="193"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="264"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="639" mass="68510" checksum="78F8FA0A8CF94EF6" modified="2013-05-29" version="1">MGATCAGWKMLLYLLVGLARGLAALVQASPFPTSLRSDITLLFQNDLNWTEFSNHPSALLLSTPLNSTSASIACSQLSESLLSTSSPFFTYDMTHQLAYQSFLGHHPFLQRYWVSPSSSGGCQAVGAFGTVVAAGCGEKLPVLCTQSARWTITGEGTVPAEWDMFPPVDPKYGVGVQSGNLSFLGTRDQLSFRFLGIPYANAPSRFEYSTVYSGPSSINATSYRSPCTQIGGMGPGSEDCLFLNVWTPHLSTTSSSSSLKPVLTNGSFGIADQVTALRWVQEHIASFGGDPRRVTVSGQSAGAASVRALLGSPPAIGLFNGAILQSDPVGSGMSAPWTYYPIITQEYNSTTQGILALTGCNGTDNVAQQLSCLKAYDPLQLVNISVVANAPVVDGTYVTTTELPLTGTGPLARVNVMIGNMRDDGAAIISYPTQGESLLNAAVAATGGLFPLPSGSNTTLDIFNLTARMGTDTIFRCLSEATAQSGLNHSLFKSLWYYQFERSYQLNWWSPNWPACVPPVEEGFPYGDPSQEYFHCHSGDLYLAFGSLNRAALPYRDAADLPFAQAVLDRWASFIRSYNPNPSMAYLTVRGYANTYNMLVQEGTWKPVGAAVLSVPERSTGWLELEQCAALNLSLATFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRE7</accession>
    <name>M5FRE7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624452.1">
        <property type="nucleotide sequence ID" value="XM_040770751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRE7"/>
    <dbReference type="STRING" id="1858805.M5FRE7"/>
    <dbReference type="GeneID" id="63685813"/>
    <dbReference type="HOGENOM" id="CLU_359025_0_0_1"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="534"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="780" mass="84909" checksum="7BCC76635F570348" modified="2013-05-29" version="1">MSTHHRRPKTLSLTSRPSISSLPIIPLLTDTEEYDTSSGSISFHAAALLLEDNASGASVRDWEGCGSASVSGEERRKSSGSSLPTVHSEQTSPSLYFPSNEVHPPEEANPPSRKPFPTTSPLQDRTSPEMDNIFEPPQLLPLMDRSRTSSTYSFSSSLSGTFGRPGPGHGQGVGVTPLPSPTREGLPKTGGEGEGEGYTSGLPSSFERKTGYGDNAGLSRDPGEPMPVSDSPEVDMEGPPRPTPATPTKSRSLDTHNLNFPNLSPSRTHVLSPTLVASPEEGAPPSNVTLSDLLQQLKRQPSVSPLPGTGRSVSVGVDIRQYATFCVLLWWRTLAAVGHSLGNPRHVWDVLTVAALSTLFPLLQYLARLVEETWTLLRIKYRFPPLSDLLKLKHETSYTLFDCFSPSQLSAGKEALSTLPLPAHSHSQFSLPAARVLLQLCALLACRQPRPGTGDRFAKHGEGYVRLAARAFGLEYVPVSALNTRGEGCCAAFYDMNSNWIVLVFHAEWKSMVDELLWTSQSPSVQLSQIHGFGKVRTCFSDRLFPTSTPSARLPYHTILQSVRILSSQLPAAHVQLYFTGHGAGGAVAALAMAAVLDIEQREREWGVQVGDGYVFGSPSVCDTLSARAFDQKLAKSWERPCRLWRVVNETDSLVHKSWNLDPQTQEYLGTSVLLSHTNPLPLLPVLPSHPAPAPTSSLPTPNSLPTPLPTPSPPAARPDPQRPERTLMDTHSRVRRLFRDWPVLRGVVAHEMGEYWELLNLPGQGRGGEGGYDNLLVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRH2</accession>
    <name>M5FRH2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625171.1">
        <property type="nucleotide sequence ID" value="XM_040773818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRH2"/>
    <dbReference type="GeneID" id="63688880"/>
    <dbReference type="HOGENOM" id="CLU_1713187_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="17327" checksum="BF2A7FE3A72627CD" modified="2013-05-29" version="1">MPSVQSFAPNYTGSTTQRQGYRILKPDITQRSVSHVNKWSTSRNRASSPPTVRGNSLQQNDDLHIWTAKARYVFFRARFQKTSNFRSKGLILRLGSEDLATMGMEISVLLLSRQAHGGYVGCWDGLANRPNKRVERPEATLRVLVVRPRLAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRN9</accession>
    <name>M5FRN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cwf21-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_29312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624567.1">
        <property type="nucleotide sequence ID" value="XM_040774311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRN9"/>
    <dbReference type="STRING" id="1858805.M5FRN9"/>
    <dbReference type="GeneID" id="63689373"/>
    <dbReference type="HOGENOM" id="CLU_067891_1_1_1"/>
    <dbReference type="OMA" id="LAHMRPR"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="54"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="19346" checksum="91A289712619B8CA" modified="2013-05-29" version="1" fragment="single">MYGNIGLITPRGSGTNGYVVRNLSALRPRDSSYGRADDFDRAPPRHREPDQSILEHEKRRKVEVKCMELQVELEEDGVDDEEVQRRVAELRDKLTNDMSGIAPTPVKSLKPSDTHAIAAAKKAELEKMSRALGTQSYVEGEAFNRELQEERRQEALRERERRDEQRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSA4</accession>
    <name>M5FSA4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Actin-like ATPase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_81198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627163.1">
        <property type="nucleotide sequence ID" value="XM_040776496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSA4"/>
    <dbReference type="STRING" id="1858805.M5FSA4"/>
    <dbReference type="GeneID" id="63691558"/>
    <dbReference type="HOGENOM" id="CLU_005965_5_0_1"/>
    <dbReference type="OMA" id="SRTPMIQ"/>
    <dbReference type="OrthoDB" id="10262720at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034663">
        <property type="term" value="C:endoplasmic reticulum chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067199" evidence="6">
        <location>
            <begin position="19"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="790"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="790"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="802"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="839" mass="92319" checksum="4C6ED500FE3C6C95" modified="2013-05-29" version="1">MRTTLLLSLLALVFHSSASLLAIDYGAEWTKAALMKPGVPFDVLLTRDSKRKLQSVVGWKGDERLFGSEAAAVQTRFPTDSFQFLKPLLGTEYSQAAAANQSAVSLARTSESERGTFVFHRSDGTAWNVEELVGMQFGYVKELAEALGGEPVRDSVVTVPAYFSHFQRQAVLDSLEIAGLRPLALINDGTSVAVNFAMTRSFPIPETHIIYDAGAGSIRATLVTFSSSVSKSKKDKDKETTLIEVKGMGYDLVAGGMELDFRLRELLEEDFAHKTGVRIQGPRPVAKLAKEAARVKAILSANIDSSVHIESLYEDIDYRSKVTREQFEAACADLKPRFTQPVLDALAMARLTMDNVTSVILTGGASRTPMIQSVVNAVVGKGKIAQNVNADESSVLGAALYGASLSPLFRTKDIKVQDLVPYPIQMSYPAGQRTIHTPLFPRGSRAGLKKTVSLKRAEDFSVLFEYKDAPLHTREEILEVSFSGVEEAVRNLTDGGAKETVAKLTVQYSDSGLLSLREAALIGEGYEQSFAGALKGLFGAGKQEDVDQEADRPGAEGEQAPLEAPEMKQDPKELPLAFSEVARSVPGLTKERKRKSRQRLMALDAAEQTKRRREEERNQLESYIYKLRDVLLSDAETVFIVYSSEAERAALRSVLEEVTGWMHEAAETAELVLLREKRAALEAAEQPIQSRVKEAQEWPQHLSDLQRALTAGRIFLTGAFESRTSDDPENPPLHSDEELENVKTILEDTEHWLQEALVANKNRAKHIDATIKTWEMRSRGILLQDAVTKLTRRKAPKKPKKMSTTSESSSTTGAAEPGKTAGVEGQNDESQIPLHRQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT01</accession>
    <name>M5FT01_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nuclear distribution protein PAC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Lissencephaly-1 homolog</fullName>
            <shortName evidence="11">LIS-1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">nudF homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PAC1</name>
        <name evidence="11" type="synonym">LIS1</name>
        <name evidence="14" type="ORF">DACRYDRAFT_80868</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Self-associates. Interacts with NDL1 and dynein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">Cytoskeleton</location>
            <location evidence="11">Spindle pole</location>
        </subcellularLocation>
        <text evidence="11">Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">Dimerization mediated by the LisH domain may be required to activate dynein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the WD repeat LIS1/nudF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT01"/>
    <dbReference type="STRING" id="1858805.M5FT01"/>
    <dbReference type="HOGENOM" id="CLU_000288_57_15_1"/>
    <dbReference type="OMA" id="WHVATKE"/>
    <dbReference type="OrthoDB" id="10264588at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051012">
        <property type="term" value="P:microtubule sliding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023052">
        <property type="term" value="P:signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000342">
        <property type="entry name" value="Nuclear distribution protein PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000002">
        <property type="entry name" value="Platelet-activating factor acetylhydrolase ib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03141">
        <property type="entry name" value="lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017252">
        <property type="entry name" value="Dynein_regulator_LIS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037190">
        <property type="entry name" value="LIS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056795">
        <property type="entry name" value="PAC1-like_LisH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24951">
        <property type="entry name" value="LisH_PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037647">
        <property type="entry name" value="Dynein_regulator_Lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109925">
        <property type="entry name" value="Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <keyword evidence="3 12" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PAC1-like LisH-like dimerisation" evidence="13">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="232"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="336"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU00666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="423" mass="46860" checksum="24ED28A676907DA5" modified="2013-05-29" version="1">MSLLTERQKEELHLSILDYLHSSGLEQAYDALRSELGLDHIPDPKARTAGLLEKKWGSVIRLQKKIMDLENKNSALQEEIALAPSARRNASQTDWLPRTPARHTLTGHRGPINRVAFHPVHTVVATASEDATVKLWDWETGEFERTLKGHTKAVQDMEFDSKGTKLVTCSSDLSIKIWDCEAEYKNTKSLVDHDHAVSSARFLPGDDHIVSASRDRTIKMWDVARGFCVRTFHGHAEWVRLVIPSEDGKLLASCSNDQTARIWDPATGEVKSELRGHEHVVESLTFAPPASYAAIRELCSLSGPAPKGPGAYLATASRDKSIKLWDVSSGQLLRTFGGHDNWVRALVFHPNGKYLLSGSDDKTLRVWDLKTGRCARTVEAHSHFVQCLAWGRAKVSGGDGGEERPVNVIATGSVDQSAKIWTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT08</accession>
    <name>M5FT08_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase eIF4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Eukaryotic initiation factor 4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_24519</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625377.1">
        <property type="nucleotide sequence ID" value="XM_040773710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT08"/>
    <dbReference type="STRING" id="1858805.M5FT08"/>
    <dbReference type="GeneID" id="63688772"/>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="236"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT98479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="397" mass="45388" checksum="AECE294A4E110B5C" modified="2013-05-29" version="1">MASTEQLQDVQAEEIESNWDQVVDNFDNMELKPELLRGVYAYGFERPSAIQQRAIVPVIKGHDVIAQAQSGTGKTATFSISILQRLDLSVKATQALILAPTRELAQQIQKVVIALGDYMNIECHACIGGTNVREDMGKLQEGVHVVVGTPGRVYDMINRRALRTDNIRIFCLDEADEMLARGFREQIYEVFQLLPQETQVVLLSATMPSDVLEVTKKFMRDPVRILVKRDELTLEGIKQFYIAVEKEEWKLDTLCDLYETVTITQAVIFCNTRRKVDWLTEQLHKREFTVSAMHGDMEQKQREVLMKEFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTTEDVRMLRDIEQFYNTQIDEMPLNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT51</accession>
    <name>M5FT51_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_43119</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:heme binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
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        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU00751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="101" mass="11305" checksum="21415AFC4EE22933" modified="2013-05-29" version="1" fragment="single">QDIIYDKYTIPKGTILIPNEWSICRDPSLYHDGDAFDPSRFLDDKGNIKASPPDSHDDYLAFGHGRRICVGKSLAINTVLIAAAQLLWAFDFHGVEDQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTW3</accession>
    <name>M5FTW3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glyoxal oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22887</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628003.1">
        <property type="nucleotide sequence ID" value="XM_040773001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTW3"/>
    <dbReference type="STRING" id="1858805.M5FTW3"/>
    <dbReference type="GeneID" id="63688063"/>
    <dbReference type="HOGENOM" id="CLU_009630_3_0_1"/>
    <dbReference type="OMA" id="PDPVWEM"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF96">
        <property type="entry name" value="GLYOXAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067241" evidence="4">
        <location>
            <begin position="21"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="632"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="5">
        <location>
            <begin position="108"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="6">
        <location>
            <begin position="491"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="660" mass="69245" checksum="B5DDE57EDECD4998" modified="2013-05-29" version="1">MPMALTVLLPLLTLLVSTTARPQPQAEATATYLATASGSILPSGAAPTNTAAPSGTGQPTRDGTVNQFQIVGNSGVSAQQMFLGTLNKVYILDKTEENLQLQVDGFPAWGSEYDLATDTVRGMFVLSNTFCAAGASLGNGSWVNFGGNQAVTWGGLTAASQTGGGPYDDWDGGQAVRLLDPCDDGTCEWVNLAPMTTRRWYPSVEPLEDGSVIVLGGDEWGGYVNDASQNNPTIEFFPSRGAPIGLNILLNSLPANLYPLTWLLPSGNLLIQTNWAAEIYDYKANVEYPLPNIPNAVRTYPGSGATAMLPLTPANNWTATVLFCGGTNLEPDQWVTNWTIAAYPADESCVSISPDISSTWTYDSTLPEGRTMGQFIMLPDSTLFLTNGGGTGTAGYGNDTWAIGHSYADNPVLTPLVYDPRLPAGNRWSRQGLGSSTVPRMYHSSALLLPDGSVFVAGSNPNPDYTVGAGVKYPTEYRTERFYPWYYSSRRPEPQGLPSNLSYGGEPFDVQLSAQDLQNNGIVNASVIVIRGGFSTHAMNMGQRFVQLNSTYTGNTDGSGTLHVSQLPPNPAILPPGPAMVFVTVGGVPSLGAFVMVGSGMGTQQVLPAGALKASSMPLPAPNTTGSGGGNVAVSAAMGGGVELGVGLLVVGLGLVALML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTX9</accession>
    <name>M5FTX9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_60100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623564.1">
        <property type="nucleotide sequence ID" value="XM_040775614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTX9"/>
    <dbReference type="STRING" id="1858805.M5FTX9"/>
    <dbReference type="GeneID" id="63690676"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="STAGWVK"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="35768" checksum="A6E2C9C4444AA3FB" modified="2013-05-29" version="1">MFSALSSDSLIVVTGITGYIASHVGLAALRAGHRVRGTVRSLQKAEALRAAYVKEGVDVSPARLEFVLVDDLVSEVQLAGAFADADAVAHVALPEFAGGVDFVPKTVESVLVPLRVAAKEKSIKRFVITSSSAAVVSLPDIPDQVLGETDWNENAIEAYKAMTREELVAQKDWWSQYRAAKALAEQAAWRFPHFQLSSVLPVVTWGPVLHGKPSLTPGWIADLLKGDTAVLSYRPQWYVDVRDAGRLHLLALTQPNLAGRRIFAAAGPISMNNVLDALTGAFPSSDLPGNVSGDLAEESRWKIDSELGRKVLGGKWISLEDCVVDTARSIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU74</accession>
    <name>M5FU74_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_109834</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626626.1">
        <property type="nucleotide sequence ID" value="XM_040768950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU74"/>
    <dbReference type="STRING" id="1858805.M5FU74"/>
    <dbReference type="GeneID" id="63684012"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OMA" id="MRVACWY"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="66"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="542" mass="59890" checksum="88CD4B67E7CCFA82" modified="2013-05-29" version="1">MAEQQSTEYSAADEKADMAHNEDAQAHIDAEKLKHADLAARILGDKQVVVTPEDNKRILQKTDSIILVILCWVYFLQILDKSVLGYSAVFGLQTDTHLVGSQYSLIGSVGYFGQIGILPFMTYIMVRVPPRILMPILVFCWGASLTGMAGAKDYGGLIAARFLLGLFEAGCLPLFTLITMSWYRRAEQPMRVAAFYGTNGFSTIIGSALAFGLGHIQSSVLHSYQIIFLFFGLITVISAFPILWKLDNSIGEARFLSEEDRLKGIERLRANQQGTGTTEFKWHQALECLLEPKTYLFFIMTFLLNVAASVANTFGPLIVAGLGFDPYTSSLLNMPFGAVQLITIFVSSWAAYNFKNKGYILIIICLPVILGTGLLYGLGRTSNLNGALLFAYYIIGFTFGGNPLIVAWIAANTAGHTKKSTVMTCYQIASSVGNVVGPLMFNSADKPYYKNGLKGTMSCFCILFVVYILQILNLMYLNKQKEKQRVANGKPAKLRDLSMMKHFEQANDHTLASAEAGHHAHLGDQAFLDMTDQENDEFVYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUN4</accession>
    <name>M5FUN4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623874.1">
        <property type="nucleotide sequence ID" value="XM_040771416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUN4"/>
    <dbReference type="STRING" id="1858805.M5FUN4"/>
    <dbReference type="GeneID" id="63686478"/>
    <dbReference type="HOGENOM" id="CLU_402250_0_0_1"/>
    <dbReference type="OrthoDB" id="3257342at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="386"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="684" mass="77635" checksum="36221C03569FF2E3" modified="2013-05-29" version="1">MHIADLVNGLANLEAYATLLKPWGALKTRPWDEELMENPIFASKACEMESKLSLDKRGITNKDCCSLYYKMVGKNKEDMVTEVELVMRPISVIGVVRRPTSPGCVHVSYVTHFSKHNLIALQSAAHMLDTDGWMEKYEKGTKAISGHAAKSVGHRRCFCQDSLRSNSPETFLVVDTYARRRDTVDTESSIALEWMCLGDEETDHASFLTSSIQNVNGDQWSHRDGSSEEEEQEEEDFADVLRTQPTCISHTQPRVHWGEEDIVQTWPSTQHRPVQALAAAQMGSTTIKKNVKRVQKLNVKDAQSKVDKHFQQKESQSRCKPAFPRECTTASQLFILKAADRANGTKAKQKCPPRDAGECRDAGECRDKFEQIQFNIHAQPKVQEHQLRTACARHPVKILQREAQLHGEVKSIAVDLLLEHYKLPLHQDPEDIANEVEHLTTNSRFLYTDLWNSFPQKIFENLMIQAVYLTAFFHDMKSNGVQFKHIFGKGQPALLALIITSIHCALEQWASGERKLGMSHKFTTQTWGSVYQDHLDNVKEFSKAFLNQFNWMMQEMYWNVMYMSLAASRAFVVKKNKRLLYVSNLLERLQAKDLASDDTKDSSIDIEWSSRAASPHPELLCTPKVEEASINLDKNLLLQSCMSHEAKASLPMVDKISSQAQTAKDKLWPAFTSTTSLLDPSSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUP3</accession>
    <name>M5FUP3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628383.1">
        <property type="nucleotide sequence ID" value="XM_040772884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUP3"/>
    <dbReference type="GeneID" id="63687946"/>
    <dbReference type="HOGENOM" id="CLU_1652096_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="160" mass="17954" checksum="560DB9350B92C936" modified="2013-05-29" version="1">MSGEEEGLPTTLTAACASNLASIRELSLLGRLRAVILQSILRATPFTTSLSLAFKDRQHSAFTHVDFLRVSEATPLDRIYVPALEMLRIDHQMFWVDPLVQLVQSRKNVPVVADLKMIGVPMEFAVDNAQLLQPLRDLAVEVVGWEPGSVPYFLDKRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUQ8</accession>
    <name>M5FUQ8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_19044</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623904.1">
        <property type="nucleotide sequence ID" value="XM_040771419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUQ8"/>
    <dbReference type="STRING" id="1858805.M5FUQ8"/>
    <dbReference type="GeneID" id="63686481"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="APIIYRD"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="539" mass="59897" checksum="8211F5BB16AD6F60" modified="2013-05-29" version="1">MTISIYALSIALIPYTTLLLPTNIPIPTSLIQPLIAFISFLLLSTILSHTYDILRRPANPQKYKIIRYRDLPGPRATSLIWGLEKDLYDDSPPGRLLERWSKEYGGAYRFRGVFGAKNITLTTPAALHHVLTTSVYLYPKPLGGRLWLGNLLGQGVLVSEGQVHARQRKQLARAFTPQALRGQHAIFERLAEGVVDAWKSLLARSPSSGEGGEGEGTTIDVQYWANRLSLDAIGLAGFGYSFGSLESAVEGTEQHPLARTFDKLTDSSGTYAAFVLRAVLFVWPGVLRIPSKRTRSIGEVRNSLGGEVKRVRREADQEGKTVIGILEQQAAAEGSGIADEEVEAQIMTLVFAGYETTSTAIAWALYELALHPSSQSELRAQLRLSPDYPLLLDAVIRETLRLHPPVLDLHRMAEQEDLVPLGEGKALWVERGTVVYVPLNVLSNEGREARWNPEQWLVPTEGKERERDIQWAFSDGPRVCIGRAFALGEIRTVVAALLREFEFAPEGEKEVEPFYSFVVRPRVRGERGSTLPLRVRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUW4</accession>
    <name>M5FUW4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623969.1">
        <property type="nucleotide sequence ID" value="XM_040774058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUW4"/>
    <dbReference type="GeneID" id="63689120"/>
    <dbReference type="HOGENOM" id="CLU_1299671_0_0_1"/>
    <dbReference type="OrthoDB" id="2787676at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="23565" checksum="3CC1AC761BE8B3F5" modified="2013-05-29" version="1">MCNTGTFGAVSPTEVLPIFRSRPWPSNLEVSRSARKSQEEDYLAGTISSRSVMARTMNGNKCSSFRRERDSQQRTEIYSSQSSFSISHLTLEMQRFLTAVTEAIVGGLGWKKFINPTVTRGSTAWPRDSGEQEKHGVRYDYDGEQEIDGTVYHKFQMQANAGNKIPSTIKKWRSKADRGTHVVMADVFVPRGGGKDDVEAALKKAHEGVKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV33</accession>
    <name>M5FV33_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_90138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627011.1">
        <property type="nucleotide sequence ID" value="XM_040776948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV33"/>
    <dbReference type="STRING" id="1858805.M5FV33"/>
    <dbReference type="GeneID" id="63692010"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="DCAEHRL"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="310" mass="33481" checksum="7EC6CBE63AC48B10" modified="2013-05-29" version="1">MGQRFSEFLPPKTKWLPAEMPDMTGKVAIVTGGNTGIGKVTCKYLLLKNCTVYLFCRSAAKAQAAISELKAQTGKKAHFIPFDLADLHSIKSAASVFLEKEQRLDVLFNNAGFMHVPIAEVTKQGYDMAFGCMVLGHAYLTFLLLPLLTSTAKSFGSARVVTLSSNGHLDAPKGGIDYSTLKEGPVRLKKLNGWTAYMQAKWGDVVFAKELARRYGAERIVSTSLNPGVIAAELARHLTVVPIFARLIAFPADPLGAVTQLYAGTAPEAASLNGVVFHPLGEAGPARADTDDLALGKALWEWLEEQVKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVA3</accession>
    <name>M5FVA3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_52083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628608.1">
        <property type="nucleotide sequence ID" value="XM_040775080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVA3"/>
    <dbReference type="STRING" id="1858805.M5FVA3"/>
    <dbReference type="GeneID" id="63690142"/>
    <dbReference type="HOGENOM" id="CLU_136924_1_0_1"/>
    <dbReference type="OrthoDB" id="446925at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="70" mass="7951" checksum="8E013C2998616094" modified="2013-05-29" version="1">MSKNKSKWPKVVPVVFWAQQISIHSATGMSHFYMAHKIYPLLPMDIIEATWLALPPDQLLSHADLVAFCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVD3</accession>
    <name>M5FVD3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">U3 small nucleolar RNA-associated protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_23206</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627131.1">
        <property type="nucleotide sequence ID" value="XM_040773152.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FVD3"/>
    <dbReference type="GeneID" id="63688214"/>
    <dbReference type="HOGENOM" id="CLU_001128_0_0_1"/>
    <dbReference type="OMA" id="NDVMWKQ"/>
    <dbReference type="OrthoDB" id="31183at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056473">
        <property type="entry name" value="HEAT_Utp10/HEAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022125">
        <property type="entry name" value="U3snoRNP10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23243">
        <property type="entry name" value="HEAT_HEATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12397">
        <property type="entry name" value="U3snoRNP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01036">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BP28 C-terminal" evidence="10">
        <location>
            <begin position="1688"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1315"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1966" mass="216828" checksum="50B18766E19FD0B0" modified="2013-05-29" version="1">MQDRTLLNPSEAEKLNASLDSFLRLLSGHIFIEASSRVLEWLVRHFRITEFNIDGVMECFLPYHDSPLFVRILSILHLNRSAGGINWTFLEAFKKINQSMPRDSLLLAMEKDSELLRFVVNMLPKGLEESTAHRALINFYTVTLLGFIKRQKTIDENISAILLPAFSRIPDYSDVDARLGAYMVLVSLSRKTRFTSKALKVLVTAITKSHHSDGDAAHLISAVVAICASQDELDSIQKKAASALADIPEIEIWLTEATTIMGSETFLRPLITTMSSHLDLTRYSTVLASLFQSNNLPQVLVAHACSTIARRLAEATRENSSQLDAIKDLGVCLQQRHPQAFAVAVQSFKEAENSDLIQSLEGVLANLTVAEAHAGDAEQSIVLGAFSADTAVRASSTRQLLDSFTNKEDLAPNVLTSLCSALLARVADSESEVLEVLYADPDRLLDAVSHDNLYAAIRDAVARDLPKKQLLTHLDFIASSLLIQHTELSSAAFFDVFLPHLLFTKTNNKTSSAVWDLLLKSELSRLPLLQGVADLFKNGAVDDDETRHDRLAEINLFVAKKIADNLVSSDHYKDLVNSFIKKTSEGPLNSQLFASLVIHALLARVSGEHQVDLGYEVLAFLRTHSQSTFVADEDTTTKLAEDIYTRSKAARTIRQLQIALLYSVAEVGRPVNVKFDFLCDVEAVTENDGRGMRYAALSRAVFRFSNQDGVSSPARTKCLIRLFKTLGDDCLAVLSGIWADHSTPPQTRAAALSLGSAMLQSVESDDTIDYQVVLPSVLVSLSDPSVIVREGGIQCLKVLAGLFRSHKKPKAIFAIDALYGLQSSHVQYLEHNDTAQYIEILLQHSDEILLDGSVLQGIHSASLMKEKGEGKKKTTFKEKVLYFLLSHIVAWRSAHARTTLLWLICNVHSAIKLEMLLPFLQKTVSAIQENQAAHHDLVQPLSASVSRNLLNIFDDTAVSSLNDQANDSFAVLKTCISIPLENAFERSVYDGTLDVLRSSITKEIMIERAIELLQLCVETIVASEQAHIVLKQVISDLLVDTVVIAALIRSMRPTDDTSEPSAKRPKTDNFVSESARSSIRQLSLLVEIVSTKSLPGDINLISVLLETLGMLVNSPSLSSVDVDYTLQLILLAIMNNAFAVQNDVSHSSNSLRIDIVVDLIRTTANPQTSRQALLTVGSLARLSNDSVLHNIMPIFMFMGSTVFQNDDAYSFSVISKTIDSIVPVMANSLKEQRTTQFDLYQRSREFLRVFTDASTHIPRHRRSKFFIHLVDVLGPQDFLVPICLLLVDNTAFRVVKQKAIDVPSTFAIPLACLQKRTISERLSVLQEVMEEAKRLSKKLADASHAEPVTFLDMSKSIDARERIPKPDVALTRQIQALLLFVGTAIELLKTPQGVEDSELDASMKRFVFQLLELAQDPTEGKRDAVISTTAFAALDKAMSIISVPTFSHAILNMLDTDDTGLQRAALSLISRLNNVTAKGRRGIAATMANIIARVVSLVVKFQKDSASVVALQAMDIIARTAMAGEESALAQAAGPLTQFAARQVVQQQLSVLNILDILLGKLGPRLIPNLLPIIELCTSIISTSDEVDLRVKAFTVPSSVLKALPNFVGSYLSRVLDAGLDVSRALPIEVESARVALLRTTAKQIKGRTLLPALEKAWQVTASREAPSVKFLGLYSDLLQRSLRAADRADVLGELRPLFKLFLDIFDVRSSYVIAEASAEFAAVESVALSAFLQVVVKLSDTAFRPLFRKLYDWHLEGGKTARGITFYRLVGSLLDQLKEIITPYMAILFDRTVELLREYATGQAESGELWLEMIDVLRKSFEYDDGGFWRDNTMMKIMSPLVDQIDVCPRITRSSCSSTTPNNALTACLSTMCKSASDDTAKALNLAVWMKARSEVVQTKLCMLSCAQALWKRDGERLSTAGYAAETVAFLVECLEDASEVVENEARVFQRQLTKLVGPLDALID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVN6</accession>
    <name>M5FVN6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_69406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626562.1">
        <property type="nucleotide sequence ID" value="XM_040775900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVN6"/>
    <dbReference type="STRING" id="1858805.M5FVN6"/>
    <dbReference type="GeneID" id="63690962"/>
    <dbReference type="HOGENOM" id="CLU_029210_0_1_1"/>
    <dbReference type="OMA" id="AGWFIRN"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="530"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="568" mass="64620" checksum="AA0DFF069F9DD745" modified="2013-05-29" version="1">MQMQLNQQQQLASVPDAVKRFIVHFHQSIRDGNLPEISLAYESGWNRLTEKFYSKTEWPEAETISPLVGDDPIFLILYRELYYRHVYSRLSPNIDDRFHSYENSCELFNYLLNSDGPAPLDLPDQWLWDIIDEFIYQFQSFCSWKNKVGSKSEDEMAMLAEATQIWSCYSVLNVLYSLIQKSQILEYLKATQAGESTEAVAELVGEYGTRSLYRMLGYFSIIGLLRVHTLLGDYTLALKVMDNVELSQKAPLARVTACHVATYYYVGFCYLMLRRYPDAIRMFVTILNFINRMRQYHTRSYQYDQVNKTGDRMYALLAICSALSPSRLDDNIMNTVKEKYGDQYTKMTQGSEGLQAFEELFTFACPKFIAANPPPYENEVQLAAWLEEPPADPAQKHLALFLSDVHAQDAVPTLRSFLKLYTSLDAGKLANFLDVDEEELVQQMMVMKQSSRSVTRPATSAGSLLQGEVVSTSDLDFAIEENTVHIAESTVGRRYGGWFIRNIEHAQRVFDSMRSQPLPITKTAAVTPPVNGQVEKSDAPAAQSRQTSGRTGRAVWGGANARRVEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWC4</accession>
    <name>M5FWC4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629093.1">
        <property type="nucleotide sequence ID" value="XM_040771119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWC4"/>
    <dbReference type="GeneID" id="63686181"/>
    <dbReference type="HOGENOM" id="CLU_590550_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="463" mass="50722" checksum="32D0301515875401" modified="2013-05-29" version="1">MAIEPMDTADEQSIRFQQIMNQSPEANELSDRAYLFYLMDCAFGPPTNFFDSLQSLVLPTGALPVLSSPSEGAPASPTSSSSLPSPRTLVQLIQAGAWDDSSSCLAPAISATNSHTPALLNDIPGNSTIERSLAPSSNPPGSLLPASSHHPGRLSTSICPRGDLGASTRPACLTRPGETVWAHQGQQDFDEIAQYLAQQFLDVSSTLSCSGDNVPAASGPWWFKIQTKLYLQICEALDMPSLQANDEHVVQDHGGTWSGRLTCEHVAAWFTSFPQAKPLTQSTFTNHQGVLKQWEHLWADKEHYYNAHKEVLSSISPDEENPQLYGAIKLLGVLGFLAASDEAERQALLSIGGYGPKWKKRSENTFQTTPLDKEDNCALPSHLKVLRFSSDPRLHAENRHGLISFSQGDDFINVEAMDHIVIHVKVPQPCEMGAKLNLKSINDLIELSWAFADIFFDNEWQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWU2</accession>
    <name>M5FWU2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627776.1">
        <property type="nucleotide sequence ID" value="XM_040768613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWU2"/>
    <dbReference type="GeneID" id="63683675"/>
    <dbReference type="HOGENOM" id="CLU_1468122_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="184" mass="21295" checksum="BCF479BB3BFC1754" modified="2013-05-29" version="1">MSAPDPGPAPEMHYQILEIDSTLIDWEGDEHDWPGWMPYVDKVFMLFDATSRRMVWVCAAIDLIRDLNLPCIVVMTKMDLPQALSTTMLDQRMWTWDISLIDSDPPYQHLSRPSYSYGHEEPEDKEEEKEEERAEDEKVEEQAVWEGEGREGEGREQAEEVEEYLPEVQEILDKAVAGEHPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXS2</accession>
    <name>M5FXS2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625219.1">
        <property type="nucleotide sequence ID" value="XM_040769118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXS2"/>
    <dbReference type="STRING" id="1858805.M5FXS2"/>
    <dbReference type="GeneID" id="63684180"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="AVANPIY"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="321" mass="35365" checksum="F5CF71AB4DC9481B" modified="2013-05-29" version="1">MESLPSLYTSMFPPAPKWGFNDIPSLKGKVVIVTGGNTGIAEVMCRELLNHDAKLYILARSLGKADAAIADLVKKTGKTNVKAIQCDLADLRSVKRAAAEFLSKERQLHILFNSAGVMYAPMSMLTSQGYDLQFGTNVLGHFYLTQLLLPVLLSTAAANPGQVRVVTTSSSANHGAPSKGIIYEYLKDGPQRTKKGDSYMEYYMSKWGNAVYAQELGRRYGNQGLFSCALDPGWIRTNLWQYQGNIRGLMTGWMLNDVEHGALTPLYAGTAPEAAKCPNGQFFVPWARAGRARKDTEYPEAGKKLWEYCVAQVQAFEAQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY31</accession>
    <name>M5FY31_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627587.1">
        <property type="nucleotide sequence ID" value="XM_040768726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY31"/>
    <dbReference type="GeneID" id="63683788"/>
    <dbReference type="HOGENOM" id="CLU_2320314_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="99" mass="10740" checksum="7944A463E2C1A872" modified="2013-05-29" version="1">MAAEKVYEESDQGLNLVSELVCDLDQQATRSILTMRFFAALVAMLSVVPFKVQAAAVKRTNFGMDTFLTPSTVCPTSVGECFGASNGESFLSFDIHCFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY37</accession>
    <name>M5FY37_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795944">
        <property type="protein sequence ID" value="EJT96457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623355.1">
        <property type="nucleotide sequence ID" value="XM_040769496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY37"/>
    <dbReference type="GeneID" id="63684558"/>
    <dbReference type="HOGENOM" id="CLU_2941669_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="60" mass="6449" checksum="3850540C55EB2404" modified="2013-05-29" version="1">MIRRPSVTRSALSQTKVLDNLVTHPNSSLYPPKAGAPAKTVNFWMTGANVSKVSADRPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY57</accession>
    <name>M5FY57_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_108794</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627627.1">
        <property type="nucleotide sequence ID" value="XM_040768735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY57"/>
    <dbReference type="STRING" id="1858805.M5FY57"/>
    <dbReference type="GeneID" id="63683797"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="LLWEQPE"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067323" evidence="11">
        <location>
            <begin position="17"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="56233" checksum="6324407FCB7D7091" modified="2013-05-29" version="1">MLVPLLATCAIGLVLGWLLVSTRRPANLPPGPKRIPVFGNLFQTPSNLLFTKLTEWSKEYGGIFSYDVMGQPIIVLSAAQEAGDVLDRLSAKTSDRPPLIKAGEFLCKNMQMTFLPRGKRWRTMRRAAHESLNVRVVKDYAPMLKDEATILVEGLVDHPDIPVSGHIHRVAASMGWRSIFGHEAIPLLGPDPSHRIEELAAEMSVAMLPGGSVVDVFPMLKPIIARSKFLRKHADRWFEELSSCFLHAYSTDQIEGQLSVSGTLKETGEKLGLTAHDGAWIGAALFFAAEDTTACSLLWFIYAILLYPETASAARQQLADIVGDRPPEFSDRDKLPHIEALVKEVLRWRPPVPMSIGHAASEDFEYKGYTIPKGAVVVANLYGIGRDPKLYSDGERFDPARFIDKNGQLKQPARDSKDDYLCFGHGRRICLGKDISIESLWITFAYLLWAFDIKKRRDSNGDEVNVFEPGFLDKGATLEPVPFPLQLCPRYIDLKERLKAANHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYB1</accession>
    <name>M5FYB1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Utp21-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_108868</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627712.1">
        <property type="nucleotide sequence ID" value="XM_040768752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYB1"/>
    <dbReference type="STRING" id="1858805.M5FYB1"/>
    <dbReference type="GeneID" id="63683814"/>
    <dbReference type="HOGENOM" id="CLU_002774_2_0_1"/>
    <dbReference type="OMA" id="CIYAWRA"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059157">
        <property type="entry name" value="WDR36-Utp21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25171">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR36/Utp21 N-terminal" evidence="4">
        <location>
            <begin position="64"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="605"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="3">
        <location>
            <begin position="732"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="934" mass="102700" checksum="BCD7C5F2E6A0EFA7" modified="2013-05-29" version="1">MDVDEPSPPPAKRLKTTRERATKQHSKQSIFAPFRALGLVTNHVPFAVQLRSYKGSTEGPQIHILTCIGQSWLLWEGGKMRLLFVGQEAPLPLSAVAFDAVDGDYIWAAAGPHLIKYYRGKEVTRITSPEEVNISQILCFGSQILALSEDGSKLFIWHTPANELYTTIDFPPDFTATHLLHPATYLNKVLIGSAQGALQLWNIRTRTHLFTFPSSRFSSAVGSHAVTCLVQSPAVDVVAIGFSSSQAIVYNIRTDESIMKLSMASGGIRAMAFRSDNEPILATASSTGQIATWDLSKSARLVHLSRMAHGAGVTALYFVPGQPLLLSAGEDNSVKQWLFDSPLAPPRFLKGRSGHSRSPHLVRYYGHDGKNILTASADRSLRCVSVVRDSRSFELSQGSIEKKASAMHISADEFKLPPAIAISWSETRTKDWDDIMTGHGEAGARSWWLLEKRIGKFSFGAGNRGSGPSVSGVRAVCVSACGNFGLAGTEDGSVGMWNLQSGILRKSFDLTKPVKGEKKKKAKESEKIVTGIVTDALNRMVVVSTLAGTLHFFDFYTTEPQAVVTLPSAAVSVVLHRGNNMLAVNCEDLVVRILDIETRRTVRELRGFKGKVLDLAFSPDSRWLITTSLDSIIRTFDIPSGCLIDAFRVNSIATSLSFSPTADFLATSHVDSVGLYLWTNRAQFTEVITKSVQEDEIVELNLPSMQGVDEAEGLEALEGEILPPSDIYATPQQLADGLVTLTLLPHSRWQTLLNLETIQQRNKPKEPPKPPEKAPFFLPTLPGTEQRFALDAQAPDKGTGKMHLNRGVLASVESEFVRKLLEEDNNGKYELFFNYVKALSPAAIDLELRSLSSTKHLVLFIHALTQRLSTHRDFEAVQTFVDVFLRIHGDVLIVNEETMGPLQELAEVQKRESERVLELITSSLGTLSFVRQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYM4</accession>
    <name>M5FYM4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NCA2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_65323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630035.1">
        <property type="nucleotide sequence ID" value="XM_040775779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYM4"/>
    <dbReference type="STRING" id="1858805.M5FYM4"/>
    <dbReference type="GeneID" id="63690841"/>
    <dbReference type="HOGENOM" id="CLU_008227_3_0_1"/>
    <dbReference type="OMA" id="QFANAVR"/>
    <dbReference type="OrthoDB" id="413313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="56539" checksum="5F90F63A369AFA60" modified="2013-05-29" version="1">MVRLMHEAARDESAAEWWGRAERVGAGAGWYLFETLPIRLYNLIIVLLRQPHPILSLLHSTRHLPPPPRSPSPVHLHPIVAHLFQLPPSPSPTPLTALLDPLHLARLECRYHKTHLFQGRDDRAEAVGRLLGVFDRLKDCQPGTDQFANAVRDLSAALPGHVELKEPIDTTPSSYAYHLLAALDSLKLSSEKHDASMAHHAPPSRWTQLWPRLVFLPLIAYVAARSLYVSREQIWGWILDAKETVRVFLISWVIEPIMDILKTIRTGEGEVKVVSPEGVKSDLDSLERMAVSLAADKLKYTPEQQAELGSSIRAGDLTAVLRIYEEDIKAPLRSAIGGTLIRTLLIQVQKLKVDVDVALSGIDKLLKSQELTFAFVGVAPSITILYFSGSWLSSLWYSGRGRGRYGGERKREEAWLSLRRVEHLLLAPEPLPPLTQGLLVLSLSSLRTYGQTHLPVRTRLREGFLEDVGYLEDVSLQRGDKRLVVQRMRADWGTVLGWTTVAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYX5</accession>
    <name>M5FYX5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_65462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630140.1">
        <property type="nucleotide sequence ID" value="XM_040775785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYX5"/>
    <dbReference type="STRING" id="1858805.M5FYX5"/>
    <dbReference type="GeneID" id="63690847"/>
    <dbReference type="HOGENOM" id="CLU_051277_0_0_1"/>
    <dbReference type="OMA" id="MTYGYMI"/>
    <dbReference type="OrthoDB" id="10250083at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.50:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000003">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00059209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="362" mass="41264" checksum="086932AA6729D4FA" modified="2013-05-29" version="1">MEALFFNVHAGFIEGIVRGYRSGLLTTQQYHNLTQCDTLEDFRMQLSQTDYGNFLANEPSPITTSTIHAKATQVLVDQFNYMRANAVEPLSTFLEYMTYAYMIDNVILLITGTLHERDTHELLERCHPLGVFDTMPALCVATNVEELYHSVLVETPLAPYFRDCLSASDLDDLNIELIRNTLYRAYLEDFHKFCSTLPGPTPDVMHQILAFEADRRTLNITINSFHSSLSKDQRARLFPNIGRLFPEGNNALARADDLEGVKNACEYIGQYRAFFDTTGQGQTNGSSALGLEDTDAALTRLENAFFAHEVHLNKLSFLQQFQYGVFYSFVKLKEQEIRSLTWIAECIAQEAKDRVEDFVPIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ63</accession>
    <name>M5FZ63_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_59966</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623680.1">
        <property type="nucleotide sequence ID" value="XM_040775600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ63"/>
    <dbReference type="STRING" id="1858805.M5FZ63"/>
    <dbReference type="GeneID" id="63690662"/>
    <dbReference type="HOGENOM" id="CLU_013783_4_0_1"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067449" description="tripeptidyl-peptidase II" evidence="13">
        <location>
            <begin position="17"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="14">
        <location>
            <begin position="241"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="196"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="601"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="622"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT96782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="643" mass="69812" checksum="A1B40B530971E5AA" modified="2013-05-29" version="1">MYLLLFFPLLVLPALSVLHEERRSIPSSYARSLDPPAPDTPLPSPLRFFLQQSNVHLGPSALLNVSSPSSPFFRKHWTKKQVDAFFAPEPKRAEAVERWLASQGIPQGKIRRSRSGGSVDVHGLSVSEAQSLLNTSYSVYTHQERGTTHLGCTEYHLPEEVAEHVDFVYPTLQFDGHAHKQGVTIPLSARESAMRISGQEPKEKKRGKVGLGVPGSGSLPKQGEQLSTDQLNGGISVCGEFIVPECLQELYNYPAPNLSAPSYPSEHLGIVEYTPQSYLPNDLEMFFGYYLSPGVGERPTLYSIDGGYPQDEYLGFEYQGESSLDLEYAMALSWPEIPMLYQVGDLSGSASFGNFLNALDGSYCGENDPSVDETFPNSYWPYPEDCGTVPQATVISTSYNYNEFDLPVSYMERQCHEYLKLGLEGITVVFSSGDYGVGGNMGMCMDDTTGAMFTPSFPSTCPWVLSVGATQIPYGTTTPFTTPEVACEDVIVSGGGFSNVFSRPGYQDDQVAGWSDNYGPVGLGYDYNTDSMRGYPDISANGAGYVVAADGEFLLLYGTSASAPVIASMLAKINSELASQGNAPIGFINSVIYANPDRVHDIISGSNPGCGTKGFSTTPGWDPVTGMGTLNFEKLLEFYMALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZN9</accession>
    <name>M5FZN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628252.1">
        <property type="nucleotide sequence ID" value="XM_040772841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZN9"/>
    <dbReference type="GeneID" id="63687903"/>
    <dbReference type="HOGENOM" id="CLU_1019502_0_0_1"/>
    <dbReference type="OrthoDB" id="3398769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067478" evidence="1">
        <location>
            <begin position="17"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="273" mass="29666" checksum="C61ADA08F9666BCD" modified="2013-05-29" version="1">MTYLYVFLFLATLCLAAPFDVRPRAGPSGQVLTPVGGTTITQLGGVLEFAYQPVTEAMNPGYATQYVNLFIWNEDTDIITPLAVGLSTPDEEEDAIVSGLITANFSFAAGGVCGNNLQLVVYEYQTGTEAPTDGFQSAAPYFAVIDCFNNGSAITSLGHDGGNWNSPAEGSTIGLHRDSELLSYSAQSGEIFFTYSMDIDVQQNTSPIDDESTWKPVIHHLSGYFAPWGAAYFSPLHWGFIGGVRLRTTVYDMLYNDWTSGTNYLNVTVVDTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZQ0</accession>
    <name>M5FZQ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_59664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623885.1">
        <property type="nucleotide sequence ID" value="XM_040775578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZQ0"/>
    <dbReference type="STRING" id="1858805.M5FZQ0"/>
    <dbReference type="GeneID" id="63690640"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OMA" id="MNGLTQV"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="512" mass="56821" checksum="2BF3703C3D493DC0" modified="2013-05-29" version="1">MSLPEKTTSKVEADEAFEPVVEDAGSVSDGDDALKLVGTRRQYVFDEEYNRRLTRKLDWVIPPICAAVYFTQFLDKTTLNYASIMGLPITGQNYNNVSMAFYIGFLVWEFPTQYIAQRLPIAKYLGCNVVVWGAIVMLHAVAPYFGPFFALRFILGMLESCVAPILILIISMFYRKNEQASRIACFYLMNGLTSIFGGFVAYGISFYPGSYAPWKIIYLLLGGLAIVVGIVVLLFLPDSPVTARFLTEEERIAALERVRDDQGGTHNKTFKRYQVWEAVLDPRTWCIVLVTMLTSIPNGALSNFSNIIIKSFGYTSQQALILSTPGGLVGAVTTVLCGYFSDRRGDRMMPIVGAVVPTIVGAAILVGASNSGIKGLLLFAIYLVQTFGSALSVIYAWNASNTSGHTKKVTINAVTLVAFAIGNIIGTEIFQPSDAPAYIPGKTAIIVLLCITIVVCVLLRVLNIRLNREKKRELERLMAEHGWGEEEVRRERERNAFADKTDRENPYFVYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0E4</accession>
    <name>M5G0E4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor RSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pre-mRNA-splicing factor rse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_21931</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RSE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629096.1">
        <property type="nucleotide sequence ID" value="XM_040772610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0E4"/>
    <dbReference type="STRING" id="1858805.M5G0E4"/>
    <dbReference type="GeneID" id="63687672"/>
    <dbReference type="HOGENOM" id="CLU_003246_0_0_1"/>
    <dbReference type="OMA" id="PRATGHW"/>
    <dbReference type="OrthoDB" id="436637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001143">
        <property type="entry name" value="Pre-mRNA-splicing factor rse-1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000628">
        <property type="entry name" value="Pre-mRNA-splicing factor RSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000068">
        <property type="entry name" value="Pre-mRNA-splicing factor rse1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="12">
        <location>
            <begin position="13"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="13">
        <location>
            <begin position="456"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="11">
        <location>
            <begin position="854"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00055157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU02199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1209" mass="133985" checksum="570839EE07B4E95D" modified="2013-05-29" version="1">MHLYNLTLQPPTAITQAIVGNFSGVRAQEIIVSRGTRLELLKPDPNTGKVSTVLTHDVFGTIRSLVAFRLTGGAKDYAIVGSDSGRLVILEYDPQANAFTKLHQETYGKSGVRRIVPGQYLAVDPKGRSVMIAALEKAKLVYILNRDAAANLTISSPLEAHKNHGIIHSIVGVDVGFENPLFAALEVDYTESDQDSTGEAYEKTEKMLTYYELDLGLNHVVRKWSEPTDKRANLLLQVPGGQTSSEARHDGPSGVLICCEGYIIWRHMDTVQHRVPIPKRRHPLDERTRDSIIVAAVMHKMKGAFFFLLQSEDGDLFKVTIDHEDEEVKTMKIKYFDTVPVASSLCILKSGFLFVASEFGNHYLYQFQKLGDDDDEIEYSSVSYPDNGMADPIPQAYFRPRPLENLVLADELNSFDPIVDAKVTNLLNTDTPQIFAACGRGARSSFRMLRHGLDVEETVSSELPGIPNAVWTVKLKADDQYDAYIILSFVNGTLVLSIGETIEEVSDTGFLSSSPTIAVQQIGEDSLLQVYPHGIRHVLSDRRVNEWRCPQHTTIVAATTNSRQVAIALSSAQLVYFELDLEGQLNEYQDRKSLGSGVLAMSIAEVPEGRQRTPYLAVGCEDQTVRIISLDPDTTLENISLQALTAPPSSICVAEIMDASIDKNQPTMFVNIGLQNGVLLRTVLDPVNGQLTDTRTRFLGSRPVRLIRVNVHGLPSILALSSRSWLNYTYQNLLHFTPLIFDPLEYAWSFSAELCPDGLIGISGNVLRIFQVPNLGQKLKQDVIPLSYTPRKMLQHPTERLFYVIESDHRVLSPEAADKKLQKLKSTGQRLDQEVIDLPADIFGRPRADAGTWASCIQIIDPANVRSVLEVPLDNNEAAFSLAITTFIARPGELFLVVGTAQDVIVSPKSCKSGFLRTYKISEDGRSLEFLHKTEVDDVPLALLSFQGRLVAGIGKALRIFDMGKKRLLRKCENKSFATAIVTLSTQGSRIIVGDMAESIYFATYKPPENRLLIFADDSQPRWITASAMVDYDTVCAGDKFGNVFVNRLPPKVGEQVDEDPTGAGVLHEKGLFMGAPHKTNMLAHYYVGDIITSMHKVALVTGGRDIVLYTGLHGTIGVLIPFISKEDVDFIRTLEQHMRTEAPSLVGRDHLTYRGYYVPVKGVVDGDLCELFSLLPTQKQQSIAGELDRTYSEVLKKLEQLRVTTTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G117</accession>
    <name>M5G117_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630835.1">
        <property type="nucleotide sequence ID" value="XM_040772339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G117"/>
    <dbReference type="STRING" id="1858805.M5G117"/>
    <dbReference type="GeneID" id="63687401"/>
    <dbReference type="HOGENOM" id="CLU_2596508_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="80" mass="8123" checksum="F6C05AFCA3D15870" modified="2013-05-29" version="1" fragment="single">MYANAVENARHGLDRGTPMQLPSSTSNDGSSRVERGVSRPASIDVSSRSPEVGSPATTCGCTCACCLEKCAVGSSVNSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1F7</accession>
    <name>M5G1F7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_78400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629458.1">
        <property type="nucleotide sequence ID" value="XM_040776335.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G1F7"/>
    <dbReference type="GeneID" id="63691397"/>
    <dbReference type="HOGENOM" id="CLU_001042_4_1_1"/>
    <dbReference type="OMA" id="CPALDNM"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000481">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000585">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="790"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1221"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="437"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="609"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="669"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="951"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1116"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1314"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1507" mass="168532" checksum="920305814B033D8F" modified="2013-05-29" version="1">MPPRRSVRSVSGTVTAAPAPAAVRSRRSAPAKASVAVKSESSRPASTLAKRSSGTAFGDEGTKAEPAPKKGRAVSTSKPPSKSKGSQPSKGVEEEEELAEAEATAVEDSGSDGDEGTVTRPNRRDMKKPRTASPEDEDEEEDNANAIHVEAPHTPNAKQRRVPSTKVSMPHPKDADNREASSLSGGRPSSTPSRTPTNTSDDDEEEEQDLLAAAAAMATPRRPTLIPATPATVRSSLLDRNAPTILQEPEPSGPKSRLVIHKMVLINFKSYAGRQEIGPFHKSFSSIVGPNGSGKSNTIDALLFVFGYRAAKMRQGKLSELIHNSADYPDLEYCSVEVHFRDIIDLPGPDAFEAVPNSELVVSRKAFKSNSSTYTINDRNSNFTEVTTLLKGRGIDLDHKRFLILQGEVESIAQMKPKAPTEHEDGLLEYLEDIIGTAKYKQAIEESLAEVDRLNEERGDKLNRLRIVEREKASLEEKKKEAEAYLKDQNELTLAQALLWQFYMWQLRANMEITGKNIDLLERKLKDETERHQEQIKDTEKLQTAYDERLKAFEIVKKETDKLVKELGTHEKEEIQFQEKKKHLGTKAKKLNKSLADDQAAKSTADALVRDKADEIKRVRKEIDEQETMLVKEEAELENIAEGLRGKTEVFNTQIQVKQKELEPWMTQVRKIQSDIDVATNEKMLLEEKAASVDKGVDQAMAAVETMKEELKGKEEKLRQLHKEKQDLEGQSRDGKSRLKVIQDEVDKMKTKVKNLRERSDEARASLSATRSEDAVLESLTKLRDTGRIKGFHGRLGNLGTIADKYDVAVSTACTSLNNLVVDTVEQGQACIDYLRKHNIGRASIIVLEKLPARNLDPIDTPEGVPRLFDLIKPKDPKFAPAFYKGLFNTLVANDLEQANRIAFGAKRWRVVTLAGQLIDTSGTMSGGGNRVAKGGMSSKLAADRVEPSVVARYEKETADAEERAQRQQAELRQAETQTELVQKSIPKVDMAMSKVQLDIKGFETRLDEAQKRAKELQLQNKPDANDAKRVKTLDADIASYAKDLEKVKKKSDAIESDIRDLQEKILEVGGVKLRSQQSKVDGIKQLIDLANERMNKAEVTQAKATKDSAKLEKSIETHTKHLDDVQVEVEALEADYASSASDLQVIRENVTKAEAALDIAKDQLEEMKSDLDEKTSYIKQFRALEMELKQKLDEAGKSLEDSKRKLDHWKGRHEELLLEYVDDDEDDTPPEREKESASDAAESANTKPVPEQINEEEVGAKPEKHIHREKQRHGNEIPIYSDDELQGSSRDQLIAQVSLLEERVQNPPNMSVLAEYRKREANFLERAQDLERVTALRDAEKRRHDELRKTRLEEFMAGFSVITSKLKEMYQMITLGGNAELELVDSMDPFSEGINFSVMPPKKSWKNISNLSGGEKTLSSLALVFALHVFKPTPLYFMDEIDAALDFRNVSIIANYIKDRTKNAQFIIISLRNDMFELSHRLIGIYKTVNATKSIAINNHALTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1H0</accession>
    <name>M5G1H0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_78405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629468.1">
        <property type="nucleotide sequence ID" value="XM_040776336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1H0"/>
    <dbReference type="STRING" id="1858805.M5G1H0"/>
    <dbReference type="GeneID" id="63691398"/>
    <dbReference type="HOGENOM" id="CLU_090389_1_1_1"/>
    <dbReference type="OMA" id="FQTKGRT"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="175" mass="18959" checksum="F3F19035018182E6" modified="2013-05-29" version="1">MSTITHITSSKQLSTLLSANNGKLAVIDFHATWCGPCHAIAPRYEALSKQYTDALFLKCDVDACRDVARDYMITAMPTFVFLKNGQKVATVRGADVRGIETALRQHSLPSSGTAFSGKGQTLGGPDASPTAAPDTASSQAPDPWAWFNNLDPQVRLFGGLIAAYLVFWWFFSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1N6</accession>
    <name>M5G1N6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TauD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_76453</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631020.1">
        <property type="nucleotide sequence ID" value="XM_040776204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1N6"/>
    <dbReference type="STRING" id="1858805.M5G1N6"/>
    <dbReference type="GeneID" id="63691266"/>
    <dbReference type="HOGENOM" id="CLU_036005_0_1_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF31">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="52"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="365" mass="41840" checksum="1BEAC05BA38AF62C" modified="2013-05-29" version="1">MPPFNREEYEYKDYLPTYPKIDYEPHVELKHDDRGHYADLEMKALLGAATKVDDLCACIGTQLDGIDLRQLTDKQKDELALLTAKRGVVVFKNQAATIYDLLDIARHYGPLHVHSTTGVPTARKLEGVHVVWSDGTKDFDRIEMERLKSWHTDQPYEINPPGLTSLKVITDPPAGGDTIWSSSAAVFASFSPQFQRYLESLYALQSSEHQKLRALAAGTYIRRPQTDFVHPVVRVHPVTGIKALYVNPSYTHRIVGIPKAESDFVLKFIYQQILECEDFKVRIRWSKDQVVFWDNRVLWHTATYDYYPYKRHALRATPVAERPESVADYEKRTGQKAKNWYEEKMKAIGEDISVPKPVFKPAGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1R5</accession>
    <name>M5G1R5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629543.1">
        <property type="nucleotide sequence ID" value="XM_040772497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1R5"/>
    <dbReference type="STRING" id="1858805.M5G1R5"/>
    <dbReference type="GeneID" id="63687559"/>
    <dbReference type="HOGENOM" id="CLU_379473_0_0_1"/>
    <dbReference type="OMA" id="TCHEMLM"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF1">
        <property type="entry name" value="IPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="730" mass="83470" checksum="2EA0D7BBC9163458" modified="2013-05-29" version="1">MIVPISKLKWVEDDSEKAAAYLNRVGELRAELVELHGKLRGVCMAHGRTMANRWQKRQKEKRKSFLKTAFPAILEVPFDLPPGRIELNRGPNESFMNVEDLSTGSNLMSLLATRTLYRLSDWVPYDKNTKSFEGFHCPWLVLLSGDNDSYACLISLDEQAKRQHKGMLGGVVGVSLGVIVLDFQIKVIKFLYNIVQLLLSDIDLSKPPKDNLPLTMADIIDLSSRSPIERYRLRAYSHPIQFSKEKLINLVLSKLLDVQDNWILLRTDPVYFHTRLQTRALYPLRGMNGKLEQSDWHAIMEQLVIAEYESLKLWSLAWSHVQTLFGLVHKSEEKNNNDCHERDLTANDSRKPTTPPLAEADHEDARSMAEESDCPETRGKLMLSTTEETLARLHVILDFIVERRESLHGMIINAPTLKHLFQRTKQSGFVPSKVTFLRTVSRREAGQNALVDLIDPLWTLGDETSFVKVIQLPRLYAVVDEIIQKDIHQRGRLPAVIHDIVSELQACDNALLEISIHPDRRYFLSEAQRIGQRDKLRGDVGCVQGWSTTTAVPTMFQERYLFDGNVPSQVQENKARRALQLLWQHFDPGCHELGESSNGSYGDTRHVEDISPAHSHDISCVGQPLITVGVKKKNFRVLQILFGPLSEMEDSDVTWEGFLQALRAIGFRADRIFGTQWRVIPSNESPWPAYPISLQEPLPGPRLTWQQARFITKRMFRHYNLQQSSFIMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1W3</accession>
    <name>M5G1W3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51674</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629102.1">
        <property type="nucleotide sequence ID" value="XM_040775051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1W3"/>
    <dbReference type="GeneID" id="63690113"/>
    <dbReference type="HOGENOM" id="CLU_001324_10_1_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="70" mass="7753" checksum="0004BD6977AB58DD" modified="2013-05-29" version="1" fragment="single">SLHTTIVDLCGCTSPQSAYVMLSHVQTLEGIAILCPFTLRSIFHGLPSDLCKKFKWLDELAAKTAKRFPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G233</accession>
    <name>M5G233_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_88467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629643.1">
        <property type="nucleotide sequence ID" value="XM_040776856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G233"/>
    <dbReference type="GeneID" id="63691918"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_2_1"/>
    <dbReference type="OMA" id="PHFKGPA"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SDR_enzymes"/>
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        <property type="entry name" value="SDR_fam"/>
    </dbReference>
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        <property type="entry name" value="CHAIN DEHYDROGENASE (ATSC), PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="219" mass="23752" checksum="C5F8706F0F57604A" modified="2013-05-29" version="1">MPSYVIAGASRGIGLEFVKQLLAKGDVVIAIARTPEKSTGLQELKGEKNLHILQGDISKPEDMRACADATARITGGSVDVLINNAAYLGYENQYNAIDEFSSDAALLDSFTNNWNTNVLGVIFTTNVFLPLLAKGDLKKVLTLSSGLGDPVFSLNTEFDWCVAYSVAKCALEMVNVKYAAKYKKEGWTFLAISPGVVNTQLEPRACFPFGVFLFHLTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2G2</accession>
    <name>M5G2G2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_81701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN2 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="GeneID" id="63691586"/>
    <dbReference type="HOGENOM" id="CLU_028981_0_1_1"/>
    <dbReference type="OMA" id="SEENWKD"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="PCI_dom"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PINT"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
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            <end position="440"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00014879"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="503" mass="56828" checksum="B711CD2369FB8CC9" modified="2013-05-29" version="1">MSDDEYMQDDEYGFEYSDDDGDDQADASLENRYYTAKSMKEDDPEAAIEEFKSIVEDEPEKGDWGFKGLKQQTKLNFLVLNRPSEALKTYTKLLSYTKSAVTRNYSEKTINGILDYVSGSGKKRRYKSRAGKKPSEQEQMEILEKFYEITRKALEEAKNERLSVKTNLKLAKLYLDKHEYPRLQALLKSLHASTLSANAAAPTGADDSTAQSATGTLLLEIYALEIQMYSDMRDYKKLKEIYNASSQVRSAIPHPRIMGVIRECGGKMWMGERHWAKASSDFFESFRSYDEAGSPQRIQVLKYLVLANMLTGAEVNPFDSQETKPYKNDPEITAMTDLVSAYQRREVHEAEKILRENKATIMDDPFICSYMGDVLRSLRTHYLIDLMKPYTRLEIGFLAKQLNVDNAEVEELCIGLILDGKVQGRIDQVAQIVELERHKGLDARRYNALDAWTTGMEKIFDNITAKAGATNDRGMGGAPMGMGMGLPFGPEWESASKGLTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G340</accession>
    <name>M5G340_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_47457</name>
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    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G340"/>
    <dbReference type="STRING" id="1858805.M5G340"/>
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    <dbReference type="HOGENOM" id="CLU_2580240_0_0_1"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
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    </dbReference>
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        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="81" mass="9779" checksum="873CA567A3482F24" modified="2013-05-29" version="1" fragment="single">DVTKDFGSKWKNIFIHMETYLELDIALNSHMWLLHYLFLRDINQDAELWQQMWNFHPLQSHKGQMKSPNERWMVGMLGKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3V2</accession>
    <name>M5G3V2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627424.1">
        <property type="nucleotide sequence ID" value="XM_040773042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3V2"/>
    <dbReference type="GeneID" id="63688104"/>
    <dbReference type="HOGENOM" id="CLU_2250041_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="104" mass="11765" checksum="9580AD2E9E0D592B" modified="2013-05-29" version="1">MRITGNSVFRLLLVRGGRAGVHDTRLITTFVQRRKTKLFEVHSGALQSTHICKCAKGPDLSKSHLLHRGRAGSWKRRTPDRWCLPAEGRDKMPAARSSFALPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3W8</accession>
    <name>M5G3W8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_80745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627439.1">
        <property type="nucleotide sequence ID" value="XM_040776467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3W8"/>
    <dbReference type="STRING" id="1858805.M5G3W8"/>
    <dbReference type="GeneID" id="63691529"/>
    <dbReference type="HOGENOM" id="CLU_004400_1_0_1"/>
    <dbReference type="OMA" id="ILLEVYM"/>
    <dbReference type="OrthoDB" id="10258882at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="592" mass="66520" checksum="10B1BFF4AE04DC34" modified="2013-05-29" version="1">MEEAKFEKAGEELYRGRLDPRLLIRLWPDLRGGLINEEETIEVFSGIETPLAKLVNVEQIARNYAPHLKPDAPASSELTDGLLAEGKKMLRMYLAGVRRDRTIWSRVLSSELAKVDRIVDTVMIKLLAEDPDAAELYRLMDSSKSYDVLEVERWFLQMSHYGAVVRLYNKLGQDVKLLDALVNVADGVWEEDDIPNPVARVADLVQASRNREVVQKYGLWLLRKSPALGLKLFTTRDPKRAVKIDEQLVLDEMMRFDESVGEQFLEWLVLQRRNSERRLHDLLAQKYLAKVVRMLRTPDVVRSWQGLVDQYRKEAPRISFLTFFGRSNLPTQEIKARLKLALFLQASTLYDVVGLTVELQKHAVLKTEGAVLAAKSADHRTVIETLVNDLQDFTSAQAYCTSGGEVISPQAASAATLPFDDLAPLATYLAEGGSGGKGKTAPVPEDAKKALLGILVQVQMAGGEGMAKQTARLLNAQAVYFEMFETLADIPENWKLKPISPFLTRSYRHAVHERHEAMILKGISSSQNLVVSERLLDMQREQGALIEEAAEDGDDPGSTEYVEKDGEWVEKPGEDEDILDIRVDPEDRTPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G443</accession>
    <name>M5G443_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase C-terminal-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_76084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631930.1">
        <property type="nucleotide sequence ID" value="XM_040776181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G443"/>
    <dbReference type="STRING" id="1858805.M5G443"/>
    <dbReference type="GeneID" id="63691243"/>
    <dbReference type="HOGENOM" id="CLU_011226_14_0_1"/>
    <dbReference type="OMA" id="KEPWFTK"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="102"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="30163" checksum="9EAFD89A987C3EB4" modified="2013-05-29" version="1">MSKPLTLWTAPTPNGSKVSIYLEELKAAYGRDKVDYQVRILNFYKNEQKEEWFIKINPNGRIPALTDHSRNDFNVFESGAILLYLTQYYDTEHKFSFDPVTHPDEYSEQLQWIFFAHGGIGPMQGQANHFFRYAPEKIPYGITRYQNETKRLYGVLEIRLSSNGGRDYLVGPGKGKYTIADMNAFGWVRTWRWSGIENLDFCPNVAAWIKRISDRPAVQAELLVVPSSHSGKKLTKEEEDKIAAENSKWIMAANQAKAANQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4H1</accession>
    <name>M5G4H1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_77996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630024.1">
        <property type="nucleotide sequence ID" value="XM_040776302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4H1"/>
    <dbReference type="STRING" id="1858805.M5G4H1"/>
    <dbReference type="GeneID" id="63691364"/>
    <dbReference type="HOGENOM" id="CLU_008915_1_0_1"/>
    <dbReference type="OMA" id="ACKRIRM"/>
    <dbReference type="OrthoDB" id="7451790at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061499">
        <property type="term" value="C:outer plaque of mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902412">
        <property type="term" value="P:regulation of mitotic cytokinesis"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031028">
        <property type="term" value="P:septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052574">
        <property type="entry name" value="CDIRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566:SF1">
        <property type="entry name" value="PROTEIN NUD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="60552" checksum="2DC9C7A9C63384AF" modified="2013-05-29" version="1">MWIALEADAPPDPEEEDNPFSEPSVARTSSRQSQSTDHSDAAFPVPRRKSSRSFIAQGNATFLTECSFEVAHDALIKHITDAEPYLVHWERLKRIDLSGKGIDSVARLKEFLPLIEQVDLNNNRISWLTGLPSTVLRLSIASNALTGLAAYNHIPRLQYLNISHNQVETFQLLNGLVNLRELHADYNCLTSLDGLESISLRVLTVRGNDIRNVDMRMTQWHDLEILDLSQNRICDIQGVDILQSLVTLNLDGNRLEYFSVLGSRLPALRALRLSDNRLTTLNVFGLDSLRTLYADNNKLSEVIGLEDCHTVHNLSLRNQSQKLYVRRNPLPTQFFCCPLPNLIYAELSSCQLATLPVLRQMMPHIMTLVLNWNHFRHLDFLADLRHLQRVVAVGCRVETLEMDPILGGLRELRELDLRMNTFTLGWYLPVKTEDDRKHRQQATTGGKTSEHDLQSSSITTPEDLDKKYRRGLPDELYVPRAMWRGLAMECCPTIDRLDGLDINDKERIKIRKLLVQLRQSGLVLDRPGESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V1</accession>
    <name>M5G4V1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_19844</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632185.1">
        <property type="nucleotide sequence ID" value="XM_040771681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V1"/>
    <dbReference type="STRING" id="1858805.M5G4V1"/>
    <dbReference type="GeneID" id="63686743"/>
    <dbReference type="HOGENOM" id="CLU_013253_8_0_1"/>
    <dbReference type="OMA" id="TCVGAFQ"/>
    <dbReference type="OrthoDB" id="15189at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF57">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067468" evidence="4">
        <location>
            <begin position="22"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="57"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="552" mass="58752" checksum="82C5853E49DF0E8D" modified="2013-05-29" version="1">MVSSLLTAVACTLAFLGDTQAVLLPVTAQFKRGPKPERRRSTQTGILTLGDQHDISYVSDLTIGGETFVVSLDTGSSDLNIEGNVPGANDQNVQIPVRFAVGELDGVMSFVDVEFGGYLVKDQIFNHVPTQQSSADDGLLGLGPSYASINWNTAQPYIKAGQLPHNAGDSLLDRIFQASSNTANCIAIYMSRNEDPSSSNVGQGVFTISEVLTQYKQVMNIPVLPVVQSSNMLEQHFSVVLDSAIGNNGQAISLPKSSVPGVPAGKMVTIFDTGYTFPQVPAAIATAIYGGVSGAKQQTLSDGGVWWTLPCTTEVNAAFVFAGKTYPIHPLDLNFQGNIVFSDLPQGTCVGAFQAITNDAAQALDGQADMILGMAFLRNVYSLFNYGDWIDSNMDQQYEPYVQLLSITDPTTAANEFHQVRSGSSASGGLAQASLDLSTTPASSQTVNSTLDWIKSHLYIVIPAAVGAVILVVLLIIGCCICCRRRNAKSKYQNLSAPAPGHGPSPNPGHSAYASPYSEKRFDMGYTYAAKTPAPAYDDPYSNRGLLEKGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4V3</accession>
    <name>M5G4V3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AVL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625675.1">
        <property type="nucleotide sequence ID" value="XM_040769098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4V3"/>
    <dbReference type="GeneID" id="63684160"/>
    <dbReference type="HOGENOM" id="CLU_009066_1_0_1"/>
    <dbReference type="OrthoDB" id="26278at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051731">
        <property type="entry name" value="DENND11/AVL9_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017:SF1">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="211"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="830"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="717"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="868"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="910" mass="98509" checksum="4C8EBB9DA2D17B65" modified="2013-05-29" version="1">MSRHSALDNVQFHSGKGTSFSPLDHDMDREMEMEMEMEDEPLSDDTDAQSISLSTPPRSPTQPRSGRPSSTLVRPEPGTGGTGTGAFFREPSPDPVLRQEMEDEEEDGEGGREVQRERQRERERDTDREVPWSPESDALPSATSQSRLLDSPRTPSSARALRSPASQQPRTPLSSRLSHILTGSPSVATMLVPRPRPASLPLAYTKGELILGVIVIDFNHLVGPKVEFAVPPSVGADEEMCGILPFLALPDGAHLSSEDYCYFHLSSTHVSPDGTPQTVFGISCNRQIQTSQLTKKAADVTRSTVQKAVVVLASKPIFGPIRDKLGVVTRAFFNQLDFGQTEILVEFYKSLEGNLTGQLTESALYMGTSLRELVHKFRHKTLVLLKMLMLQRKIMFFGQPVETLCTYQYSLVSLIPGLLDHLADCATPFHDRRENDHDRPSELRTSDRLSLLRYLGLPLNVFGKNAFFQPYLPLQEVDMLRSASSYLCGTTNNIVTQQRDSKPDLLINIESMAFEFADQKLERSVLLTPADRKWMDEIVRSVQETWVEEDPSRPSGMQFLGSDDFLRSKFEDYICSALSAIKYADFLAKGAKNDVMISGAPSPAEVTQRFGESFIAGFRQTRCGQLWDRTTDPVLFDICEPRHPCDTTPSLAADIGLRLTEGLHELNLEERMAPAREALNTAWTSGLKAAEGLQANIAAGLQSRFGSSGSGTDLPAGGQQTQQSQQQQQQPQQQGTPRPGTGLRQLSLVREGLAPAFQQGASVATEGAKGVAGVVGGWGSFLAGRVGAFAGGVQTPTTPTAPTPVTPVAGKQGAAKGYFWERRSTDGLAAGSPAGGGTGLLGVGGTPSGRASMDMPREMKEGRPSSGEGASVSTGSSWSWLSRASSGSGTSVGGSESKEETLGLPVEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5G588</accession>
    <name>M5G588_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BNA5</name>
        <name evidence="6" type="ORF">DACRYDRAFT_19924</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G588"/>
    <dbReference type="STRING" id="1858805.M5G588"/>
    <dbReference type="HOGENOM" id="CLU_003433_4_0_1"/>
    <dbReference type="OMA" id="LPGWNSH"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="48812" checksum="4307FFA97F697058" modified="2013-05-29" version="1">MADSTDLQAQSPELLDERDSLNSFRDEFYIPQNGAVGASNDLPADQPCTYMCGNSLGLLSKLSESLVQGELRVWATRGVVGHFSHPYGREWVEFGEKLSPLLAPIVGAHSNEVISMSTLTANLHLMMNAFYKPTKERFKILCEARAFPSDRYAFHSQASAHGFDPKEAVVAMSPREGEHILREEDILDIIAKEGSSIAVICFSGVQYYTGQLFDMQRITHAGKHAGCIVGWDLAHAIGNVPLSLHDWGVDWAVWCTYKYLNSGAGGIGGLFVHSKWDNIKKPDYAGWWGQQLSTRFQMPEDFTPIPGAWGYQQSNPSCLTLASLLGSLEIFQSAGGVQATRKKSVLLTGYLDGLLRQSNFYCAPEGPSFTIITPSDPFRRGAQLSLLFSSLGTMQKVFDGLTNAGVICDERQPDVIRLSPVPLYNTFVDVKRAVDVLEAVMGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5D8</accession>
    <name>M5G5D8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NADP-dependent mannitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_118268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625865.1">
        <property type="nucleotide sequence ID" value="XM_040770553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5D8"/>
    <dbReference type="STRING" id="1858805.M5G5D8"/>
    <dbReference type="GeneID" id="63685615"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OMA" id="EHIALNM"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF6">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="255" mass="27596" checksum="DB3C8A83414EA09C" modified="2013-05-29" version="1">MPFELELPSKSFVVTGGNRGIGYAISRAIAQAGARVAVLYRSSADAPAVARALQDEFGVMVRAYQVDVADSARLEVVYNQVVRELGPIGGLVAAAGIAVSKPAVNMTRDDFLRIFQTNTWGPYNSAACLMRLWIRHNYHDGRIVIVSSIGGRRVSRGTSVSFYQASKAAASMLGRSLAQEWARYARINVLDPGYIATDMTSSMTADERRRVESTALLNRFGTPDEVANLALFLLSNQASYCVGTSYVCDGGIVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5E3</accession>
    <name>M5G5E3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627939.1">
        <property type="nucleotide sequence ID" value="XM_040777287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5E3"/>
    <dbReference type="GeneID" id="63692349"/>
    <dbReference type="HOGENOM" id="CLU_1061822_0_0_1"/>
    <dbReference type="OrthoDB" id="2537258at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="262" mass="28738" checksum="C73D21D34F46542F" modified="2013-05-29" version="1">MATAAPPPRPQHHHQPIAQRCPSCPPEQTSFDWAVSVLSQPLPPSVREILTAYSKNGREDRELLLTLLAAKTAEDNRIAHQMALHRSLLHLQYDLPLSPPPEHSSLPHPYPLYPDKPHTIERSVAYTAQDHTYPSPSTSSPPGLGSRSPPMPPAPQALGKRPRSPVYAQYAFDSGEKTSPPTRSSPMSLRGLLDPAPLSTPTPSAQGQEDRPSKRPHLSPAVEERASLSPREAAYARVPESSVRLSPGHRVSHERTRSRDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5G1</accession>
    <name>M5G5G1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_45666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632385.1">
        <property type="nucleotide sequence ID" value="XM_040774658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5G1"/>
    <dbReference type="STRING" id="1858805.M5G5G1"/>
    <dbReference type="GeneID" id="63689720"/>
    <dbReference type="HOGENOM" id="CLU_042321_1_0_1"/>
    <dbReference type="OMA" id="MSKPLAF"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="5">
        <location>
            <begin position="71"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="272"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="312"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="384" mass="43150" checksum="0914F1DD053FF5E4" modified="2013-05-29" version="1">MSAPKLSFSLGSKAKATVGASPPLKRTAAVAFGNDEQDAVDAAPTARASGSKTSVNKQLMAQSVAMSKKVKQRQDEAKRVDATVFMYDEVYDKMQHAKKAAETKREEESQERKPRYIKSLLESAETRRLDHLRAEEKMYQRERETEGDMYAGTESFVTQAYKDQIAEMREAEEEEKKREEANRAKAGAAGMSHYYKKLLERESAAHDAAVAAGNTVGPTMPQGPNLTIQRPPEMEPLSDLQLAKEAALRGQDVEVNDSGEIVDKRELLLPGLNLSAPNTRRLGGLTVDKAKPKQSSEQPLVHRAVGAAASQREIRERQARQLDEQLETEERRKVQEQERKEREENERRAERRNDDQAVMSARERYLARKKARSENPQKIDDASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6L6</accession>
    <name>M5G6L6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6L6"/>
    <dbReference type="STRING" id="1858805.M5G6L6"/>
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    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="96" mass="11238" checksum="9EF7AE2D3B4AA0B6" modified="2013-05-29" version="1">MSRQLQGRCTFCGWGYDKIVKVFETLNVDFFYLEYDTPRARSFELLQFYPRNKAVVLGLVSTKNAQVEDRDYIMTRLEEAARCLGDTKKERISISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6Y3</accession>
    <name>M5G6Y3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626415.1">
        <property type="nucleotide sequence ID" value="XM_040768912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6Y3"/>
    <dbReference type="GeneID" id="63683974"/>
    <dbReference type="HOGENOM" id="CLU_152691_1_0_1"/>
    <dbReference type="OMA" id="TGKHHDK"/>
    <dbReference type="OrthoDB" id="2532734at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="75" mass="8398" checksum="A7E8D7AEBB5F8E22" modified="2013-05-29" version="1">MSSESDKKEFHILPHPAKDNNPEQPGEGLNWGKFSGPAGAFHAHGPEIPTQEQIQNLEQPLSKEELKKRAEELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G775</accession>
    <name>M5G775_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_75448</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631473.1">
        <property type="nucleotide sequence ID" value="XM_040776136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G775"/>
    <dbReference type="STRING" id="1858805.M5G775"/>
    <dbReference type="MEROPS" id="S10.001"/>
    <dbReference type="GeneID" id="63691198"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OMA" id="HFEHIDE"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000226">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="54539" checksum="8955C79FA299C105" modified="2013-05-29" version="1">MRLLALLLPALTSALQLPLRFPQSYGSHPTAPVSPLQDFPAPEQSLSALSSEEYTTLTHTQFPGYAVRIRQTTGWCDPNVRSWSGYLDVGGGAKHLFFYFFESRRSPSTDPLLMWINGGPGCSSSLGLFMELGPCRLSPSGNETVPHPYAWNEQANVFFLDQPVGVGFSYADYEGVDNTEDAAKDVAAFVSIFVETFVQFNGREFHMAGESYAGRYLPVFASEIVDRNKRAPALGLQEINLKSVLIGNGITDFMTMIPAYYEMACTGASVPPILDISQCVRMKRALPRCQQMAQSSCVDIFDNLACTAAELFCSSELEDPFFASGMNPYDISQECDGPIEETLCYPIVRVIERYLNLNSTRKTLGVDDKVRRFAGCSAEVGTAFSQKMDMVAPGPIYITALLERGINVLIYVGTLDWICNWVGNLAWVEALQWGGAQGFEAVPMGEWQVSGGRAGITKGWKGLTYATVEGAGHMVPLDKPVEALEMVNRWLDKMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B4</accession>
    <name>M5G7B4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase V1/A1 complex subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626555.1">
        <property type="nucleotide sequence ID" value="XM_040773359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B4"/>
    <dbReference type="STRING" id="1858805.M5G7B4"/>
    <dbReference type="GeneID" id="63688421"/>
    <dbReference type="HOGENOM" id="CLU_073641_0_0_1"/>
    <dbReference type="OMA" id="QHMMAFI"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="25405" checksum="8037FE68974720C2" modified="2013-05-29" version="1">MASRSGPLNDDEVISETSKMVAFIRQEAQEKAREIKVKADEEFAVEKAKLVRQETAAIDANFEKKRKGAETSIKIEHSTATNRARLRVLAAREQHLHTLFEDARRQVVLIAQQDEKKYGQLLEGLILEGLLRFLEPSVLVACRPSDVALCKSASQRASASYTSTSGRSVSISVEGSLPKDSAGGVRLAAGSGRIMLDNTLDERLGLLEDSMLPEIRTDLFGKSESRHFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B6</accession>
    <name>M5G7B6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628609.1">
        <property type="nucleotide sequence ID" value="XM_040772698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B6"/>
    <dbReference type="GeneID" id="63687760"/>
    <dbReference type="HOGENOM" id="CLU_2967216_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="59" mass="6676" checksum="F9DBCAB61BE2235B" modified="2013-05-29" version="1" fragment="single">MFRPTRLVQAIKSVLWSSKLNNPYGSDLAAKQAVEQQVLQHVNKNRKDIEERGASVLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7P8</accession>
    <name>M5G7P8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Imidazole glycerol pho</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_22351</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628804.1">
        <property type="nucleotide sequence ID" value="XM_040772754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7P8"/>
    <dbReference type="STRING" id="1858805.M5G7P8"/>
    <dbReference type="GeneID" id="63687816"/>
    <dbReference type="HOGENOM" id="CLU_037550_0_0_1"/>
    <dbReference type="OMA" id="GNYGHFV"/>
    <dbReference type="OrthoDB" id="10254903at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="583" mass="62844" checksum="F5427D5B7D471AF0" modified="2013-05-29" version="1" fragment="single">MTRLFLLDYGAGNVQSLANSLTALGYEFEWIKSTDDFHKADKLIFPGVGAFGGAMETLQKAGLTDPLREYIDSGKHYFGICIGMQVLFASSTENPEIQGLGIIPAPIEKFESLPSRPVPHMGWNGVRLVDEENKEQEAACTGLSEDLSYYFVHSYRAAYDPSPHCPSSSWAHSVTKYGQCLFLATVRKGNAFACQFHPEKSGPAGLQVLKSWLDAPISVVNSSCAVPMVSKPLQAKPRDGFTKRIIACLDVRSNDDGDLVVTKGDQYQVREKAPASSDATQVSVSGAVRNLGKPLDLTTRYYMEGADEICMLNITSFRNSPLSDQPMLAMTSAACARIHVPLTIGGGIRDLVEPDGTKRSALEVASAYFRAGADKVSIGGDAVVAVEQLVERKARGEPALTGTSSIETIARPYGSQAVVVSLDPLKKYVEASWDQAAFGPIPAEDELIHAKHALSPLPSEAGSEKKWTYLCTMHGGRTVRPLTALQLARGVEELGAGELLVNSIDRDGQGNGYDLDLLTLIRKNVSIPVVASSGAGKPQHFVEVFEKTGVESALAAGIFHRSEVEISEVKQALKESGILVRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8G8</accession>
    <name>M5G8G8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_107084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629044.1">
        <property type="nucleotide sequence ID" value="XM_040768405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8G8"/>
    <dbReference type="STRING" id="1858805.M5G8G8"/>
    <dbReference type="GeneID" id="63683467"/>
    <dbReference type="HOGENOM" id="CLU_024572_2_0_1"/>
    <dbReference type="OMA" id="CVVIMSN"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015237">
        <property type="entry name" value="Alpha-amylase_C_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006968">
        <property type="entry name" value="PRK09441.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006969">
        <property type="entry name" value="PRK09441.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09154">
        <property type="entry name" value="Alpha-amy_C_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="7">
        <location>
            <begin position="1"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="485" mass="54817" checksum="31E528702CA24993" modified="2013-05-29" version="1">MQAFEWYCEGGGVHWKKLQSLLPDLAAMGITAMWLPPPTKASNPESVGYDVYDLYDLGEFDQQKSTRTHWGTKEELITLIADARAKNLVCYVDAVLNHRFGADRTEKFGVVEVDQKDRTKEISGLYDIEGWTGFDFPGRHDQYSKMHFNFNHFTGVDYDQGTGKKGIFKIHGDGKNWSSGVDSENRNYDYLMGADVDYDHPEAREDVIKWGKWIIDEIGAAGFRFDAVKHIDRGLIADFIKIVREQTHKPAMFAVGEFWKDSIQDLETYLSALGTQFSVFDAPLHYNFKEAGEAVADFDLRKVWEGTVVKERPIDAVTLVDNHDTQIGQSLESWVAPWFKPLAYALILLRPDGYPCVFYGDLYGTLGSSPQPPVSQLADLIRARKHFAYGPLRDTWDHPNCVAWVREGDEVHDGCAVVLCNGDEGVKKLDIGTSHAGEKWTDVLGWHAGEVIIAEDGWAEFRCPAKSVSIWTWEKARGREAFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8V3</accession>
    <name>M5G8V3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase/deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_47904</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631509.1">
        <property type="nucleotide sequence ID" value="XM_040774791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8V3"/>
    <dbReference type="STRING" id="1858805.M5G8V3"/>
    <dbReference type="GeneID" id="63689853"/>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="OMA" id="WWEFSNI"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="18"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="286" mass="32873" checksum="F98B43CA78BE18CF" modified="2013-05-29" version="1">MVKKVLCGFGVDVDAVAGTLGSYAGEDSPNDISRGMFAGEVGTPRLLKLFKKYDMKTTWFIPGHSLETFPEQMAMVRDAGHEIGLHGYSHENPVAMTLQQQKDILEHTFKLLTDFCGKPPKGSVAPWWETSAEATELLLAKGVEYDHSDMSHDCQAYYLRDQDNWTKIDFSQEAKSWMNPLVRGKPTGLVEIPASWYLDDLPPMMFIKKSANSHGWVDTRVVEQLWKDQFTYFYREYDEFIFPITIHPDVSGRPHVLLMLERFIEWVNTHEGVHWVTMREMADDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G961</accession>
    <name>M5G961_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631614.1">
        <property type="nucleotide sequence ID" value="XM_040771908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G961"/>
    <dbReference type="STRING" id="1858805.M5G961"/>
    <dbReference type="GeneID" id="63686970"/>
    <dbReference type="HOGENOM" id="CLU_026126_12_0_1"/>
    <dbReference type="OMA" id="WAEPCKT"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000092">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="24673" checksum="541A34180E328648" modified="2013-05-29" version="1">MATPSNYHPVDSPAHFQALLSEDLTRVSLLYFWAPWAAPCKQMNEVVLETAKRYPSLLVLMIEAEEQPDISESFEIEAVPSLILLRGHTLLSRISGADAQALQNALASHLNNGAGTASESETPEQMNARLKSLMNRSKVVLFMKGTPEAPRCGFSRQTVEILKKQGVAFDHFDILSDDCVRSGLKVINNWPTFPQLIVNGEFVGGLDIIKEMVSTGEFGDLLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9C4</accession>
    <name>M5G9C4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627290.1">
        <property type="nucleotide sequence ID" value="XM_040773189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9C4"/>
    <dbReference type="GeneID" id="63688251"/>
    <dbReference type="HOGENOM" id="CLU_2049628_0_0_1"/>
    <dbReference type="OrthoDB" id="3397483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="120" mass="13357" checksum="B599CE91E15EAE4E" modified="2013-05-29" version="1">MVVRGLGLWGNIVVLAYNPNGHQLLLRIPEDGYDTLYRLQDRRSMARRPSEEWNVLSYYVEEGAKVTAPMLDASEPCCRVNTDFMSADAARLADCDSVYGVDMKAKQSALGRLGFPNLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9N4</accession>
    <name>M5G9N4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_78409</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629471.1">
        <property type="nucleotide sequence ID" value="XM_040776338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9N4"/>
    <dbReference type="STRING" id="1858805.M5G9N4"/>
    <dbReference type="GeneID" id="63691400"/>
    <dbReference type="HOGENOM" id="CLU_043316_0_0_1"/>
    <dbReference type="OMA" id="KNGKWWQ"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="267"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="326" mass="34099" checksum="E760224D8F9CD6BC" modified="2013-05-29" version="1">MPARGGDGYDFRPIVTHYLFLFTFILAAIGWLVSFVSQCAVEAQWGNGPVGVLWFAIFLQLALIIGVFHSLATDSIATHRLQISVFGGVMIVFAVNGANVGIFGGAASEQAMGAGYLILAIVDIVWVLYFTAEEDSYMYHIFQQMGSGGLSGPSRGNRRRTRTSTMGNMGISSGGGNGYASGGYSNADVGGGGIGGPGSLTGGFGAPKSSFGDHRDSKPISGVLSNPGSQPGAAPTAASEREANGSITNQSQPLMSTGDTAQSAGDTYAYRARALYAYTASPDDPNEITFVKGEVMDILDNTGKWWQARKQDGSTGIAPSNYLQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V4</accession>
    <name>M5G9V4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627515.1">
        <property type="nucleotide sequence ID" value="XM_040768705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V4"/>
    <dbReference type="GeneID" id="63683767"/>
    <dbReference type="HOGENOM" id="CLU_2003836_0_0_1"/>
    <dbReference type="OMA" id="ATICHEM"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="14153" checksum="91044CBEB5D2AF63" modified="2013-05-29" version="1">MSTNVFMPPSGPAQDLCMMQLLPIYKHVKLSENSLWATICHEMVRILDNLQIKLSSVNLVHFHWEEVTEDGFSKHLTSRIMIWISVLPDSTTGNATFNSSGDILQLLRKHDIYNVNIAYHELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAK8</accession>
    <name>M5GAK8_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632289.1">
        <property type="nucleotide sequence ID" value="XM_040767832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAK8"/>
    <dbReference type="STRING" id="1858805.M5GAK8"/>
    <dbReference type="GeneID" id="63682894"/>
    <dbReference type="HOGENOM" id="CLU_1310076_0_0_1"/>
    <dbReference type="OMA" id="WSHAFAI"/>
    <dbReference type="OrthoDB" id="3038148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="210" mass="23618" checksum="1ED59DF2AA6F2C9A" modified="2013-05-29" version="1">MQEALISDTVNALPLAEWKEFTRTVLTCAYMALADMLMTWRCWIVWNRRLCVVALPIVLPISCKVMMVLFLRAIYLSTDSIEGIFAQSLSHWFTPILVLTLCQNLLVTCLIFLRVRRMNSILTTRTGSAPFRPILATILESGILYSSTLFIWLINSSANGRLRYGRGSTSFSVASSSTSVSADILRSVPYLRQIFGHEQRLDTSIQDPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAW4</accession>
    <name>M5GAW4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632933.1">
        <property type="nucleotide sequence ID" value="XM_040769519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAW4"/>
    <dbReference type="STRING" id="1858805.M5GAW4"/>
    <dbReference type="GeneID" id="63684581"/>
    <dbReference type="HOGENOM" id="CLU_480598_0_0_1"/>
    <dbReference type="OMA" id="EAYTINR"/>
    <dbReference type="OrthoDB" id="3363734at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="567" mass="60750" checksum="E9B9E5E656BB163A" modified="2013-05-29" version="1">MPEVLRRRNDSPPQPLSSTGDCSPSTDENSSRAPSSRPRSQLFNFDKAMAWLSRTPATPTRPTSPTQSTTSGGRSPRSPPSKPPRSSLSTPPASPKAKAPPLPTQPAARPSRDELRKTTVRSKESEQALMDPEAYTINRAKLVNLRPVIDTSPPSTIRRAGGPPTAQSRPSVKPLTPCRSSLKRSTNDVPPSPSFPPSSIVPFNRLVLEPSALPPFEPQLLAGPPQSGTYSRNSLVTLETSSMTMRTTIDTLTSRPSLLAHYILELCPNPPSGPPKVPTETLHIFLDRPSSPYNIILSYLRLPRSRDNSLPALPRAVQLPSHSQTTSMVGVSKLEALLDLRDEARWLGLEELEAMCEEELRTAGLVKPTKHATIAEETESDLPPTTASSVASAAPSLSSHEGEISPIIPPERSIPTPPTSSDSDLTPPARTRSPPTTPSANAGRATTVARARPVPRRQPSNSYQGSRPLPAIPTSQASSERRSSEPATNGLPTAKAQTLAPDSKTAPSLTEDEKAHRAREKLSEALSLRRRNAGSIIHSPIIGLAALAPEPRSSIASEGSLSPGRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB26</accession>
    <name>M5GB26_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_19420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633023.1">
        <property type="nucleotide sequence ID" value="XM_040771501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB26"/>
    <dbReference type="STRING" id="1858805.M5GB26"/>
    <dbReference type="GeneID" id="63686563"/>
    <dbReference type="HOGENOM" id="CLU_021993_6_0_1"/>
    <dbReference type="OMA" id="KVTWICA"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="98"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="485" mass="52030" checksum="BFDFA03051BB1B50" modified="2013-05-29" version="1">MAETVEPLDYLEPALAVPYPAHARTGSRSTDRRPSFSAFSQTARVTAHDLPVLGNGTDIELTSVNSKAPIEDAVSETPAESIHAPEPISPSQKRLFLYVLACCWSVVVMGWNDGSTGPLILRMEAFWNVGFAVVSLLYVCSFVGFIVAGLLNVWLSDKLGFGKIVVVGSSCQLIAAVLESTGPPFPVFALAFAFNGFGGALLNAHLNTLIASMPDPAPKLGILHMSYGFGAFLSPFAATQFAQMPRWSIGYIVQTGFALTGVIIYVVTFRFRTEAQILGAWLDSDGPIEPVRGNKMKQIFQLSTVHVLAFFVLVYVGLEVTLGGWIVTYLVQVRGGGPSSGYASSGFFGGLALGRVLLLWVNKKLGTNRVIYLYSFLVLGLLMIVWFVPSVIGDAVAAALIGLLLGPFYPLMIGVSRQILPRGLLTGAIGWIGSFGQAGSALFPFITGALAQKYGIKILQPMLVAMMAVDICLWAALPYTTRLMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB47</accession>
    <name>M5GB47_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_115444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630121.1">
        <property type="nucleotide sequence ID" value="XM_040770004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB47"/>
    <dbReference type="STRING" id="1858805.M5GB47"/>
    <dbReference type="GeneID" id="63685066"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_1_1"/>
    <dbReference type="OMA" id="MWPLCTH"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="17"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="452" mass="50227" checksum="E93925A3A085537D" modified="2013-05-29" version="1">MSPNGASDSKSNSERPVKIIIVGAGFAGLSCAIESRLKGHDVILLDKFPKLKVLGDIISFGPNAGRIFERWGLHDKMWPLCTHLKTFHLNTWKGDLITAQPLNEKEFGSYSYNGHRGELHQILFDHAVELGVDLRLSANVTEYWEDDHAAGVVSNGERLSADVVVGADGVRSKARAMVLGYFDQPEPSGYAIYRAWFTAKGSGIDEDPLSDYLVKDGDAFYGWIGKDVHMLSSSSKGGKDVSWVITHKDTADIEESWSFPGKMEDVLKIVEDWDPRCAAILSKAPSCVDWKLVYRDPLPTWISKKARIAVIGDAAHPFLPTSIQGASQALEDGVTIAVNLKLSGPEEAPLSIQAFEKIRYQRVRRAQRTGETNRDKWHQADDKKAVEDPKSVALNREEWLLGHDAEKHAWEAYPDTAKDIKEHGYHLPELPEGDVAAERVAKAREEYLAKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB62</accession>
    <name>M5GB62_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633068.1">
        <property type="nucleotide sequence ID" value="XM_040771516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB62"/>
    <dbReference type="STRING" id="1858805.M5GB62"/>
    <dbReference type="GeneID" id="63686578"/>
    <dbReference type="HOGENOM" id="CLU_053720_0_1_1"/>
    <dbReference type="OMA" id="DVFTWQM"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="207" mass="22981" checksum="4699E3062369851B" modified="2013-05-29" version="1">MSSTAVHTVEKVAGEAKHEVDTAADKGFDTVDSNARYLAYFSRLNTAIRAGSRYFAYTSDVGEAFRPVVNPRVVTAAYGISWAYVLGDVSYEVYKSYRKGPTPLEAQSFSEPARLSLMAVKRGSFQAIASMALPALTIHTVVRMCTSAFKDVKNVRLKAWGPTMTGLAVVPFLPIFFDKPVEHVLDRSFDWIEDQIRKEEVASKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBI7</accession>
    <name>M5GBI7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628265.1">
        <property type="nucleotide sequence ID" value="XM_040768559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBI7"/>
    <dbReference type="STRING" id="1858805.M5GBI7"/>
    <dbReference type="GeneID" id="63683621"/>
    <dbReference type="HOGENOM" id="CLU_1740468_0_0_1"/>
    <dbReference type="OrthoDB" id="2100988at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="16780" checksum="82BFDAC9E34EC26B" modified="2013-05-29" version="1">MGGEMMGSQRVRVRLAGNCLGLEDQRSRREQIVLLTAQRAAACSSSTSKSDYYNGHGHGHAPVEHGHHHLPPGQFPYPKHVWSPAGGWWTRPKNWVTNTAVVIGGCAVISYFAFRYSAEHEHRLAAPHRPVPSQLWAKEFKDGKVKVIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC29</accession>
    <name>M5GC29_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632929.1">
        <property type="nucleotide sequence ID" value="XM_040771472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC29"/>
    <dbReference type="GeneID" id="63686534"/>
    <dbReference type="HOGENOM" id="CLU_496584_0_0_1"/>
    <dbReference type="OrthoDB" id="10621453at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="549" mass="58773" checksum="AACFB529EEAB7E4C" modified="2013-05-29" version="1" fragment="single">MPPPAPLAVPAVLNGQGGKGASAGGRGEMGERRGRRMSVPLLSALQEEPQPLASPRALLPNSVRLVHPQPQHLPRPAPAHSQAQAQAQAAQAAQGAQGYPLPCPTPALEHPYPHASHAHSLHSPPTASTSSGNPRCSSRVFAPLAEVGTPGNPAMPLVPASASLHLLPPGRLREMEWLAAEERRRGAELGEERRERERGGIAERAERAAGKDRGSTLPSVAAAAKREKEERERERVDEREREEREKERYRAEVRRARERSERLRRGRREEDIPIAEGEGWDVNNRRRRPLLPLIVPPALGRPVPQNSNTLPSPPSNSNANGAPNQNGAPTSNPPRPARARTSTAPASISSRPEEPQPSAPPTPASPTKASQRARSSSRAEGKERERERQRVNSTGRERERVKLDPAAGAQAQRRMSMIPLSPGGPFSPPLAGYRYAASPVPASPVSPVGHPSLPTLPTLPTLPTLPTLPSVPMPVSPLAASQSLAHIQLQMQLQAQAQLAASQSLAQLQFQQLQIQQAMALQAMGGQRAGTMRGLGTGMGVEGGTQRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCK9</accession>
    <name>M5GCK9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TFIID-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_73654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633169.1">
        <property type="nucleotide sequence ID" value="XM_040776017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCK9"/>
    <dbReference type="STRING" id="1858805.M5GCK9"/>
    <dbReference type="GeneID" id="63691079"/>
    <dbReference type="HOGENOM" id="CLU_068315_5_1_1"/>
    <dbReference type="OMA" id="WNMKDEW"/>
    <dbReference type="OrthoDB" id="341924at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="241" mass="26146" checksum="64CF0C4A31EA428E" modified="2013-05-29" version="1">MPGTVLPRDARLIALILSANPAISDAQPQVLHQLLEFSHRYSSQVMNDSLVYAEHAGRVGNITMEDLTLAIQARAGWEFAGRIPKEYLQSLADKTNSVPLPSIPETYGVRLPPAKHCLTQVDFDLVPNRPPPGSDYYYDEEAAKYEQDAEGEWGLVDAEGEADAAGEDDAMGEDEPGLGDADEGGDLFGEDDEGDDMDDDEDTSHDPLAGLQSMSNGFGQPGSGDYQPARRLVVEDEDYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCL2</accession>
    <name>M5GCL2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_113011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633174.1">
        <property type="nucleotide sequence ID" value="XM_040769546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCL2"/>
    <dbReference type="GeneID" id="63684608"/>
    <dbReference type="HOGENOM" id="CLU_1299660_0_0_1"/>
    <dbReference type="OrthoDB" id="10433611at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="24500" checksum="A2845F65BED5BE85" modified="2013-05-29" version="1">MSPIRQYQQKLEGSGYEVEIDLGQLEFSISRDTPFNMSFSHRGSDLVYKATRVARGCCITCTTHGRTREVARLYRSKDDGEYIKVKFSEQQAQSLEDFLLVVKPRSMMYRIDIDEEIYASFSKDHFTLTDASGTALAYDTRVPMGLFRERIPAIFHISIDLLDTMDYIFVAYICMERWRREGTTSLQSRGYSQAWQNTPGLLCFEGPWGEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCX4</accession>
    <name>M5GCX4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628925.1">
        <property type="nucleotide sequence ID" value="XM_040772788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCX4"/>
    <dbReference type="GeneID" id="63687850"/>
    <dbReference type="HOGENOM" id="CLU_2158267_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12352" checksum="0AFBDF35B9B763FB" modified="2013-05-29" version="1">MPPAKFRGLSDTLGTLFQNDSFKFEMVGLTPENKHYNLQIKRVDGEDHVLAFIIAPRTAYATPSEFRRALKQSGREGGHKTELANGTLPFPTRAMIDVIIQPHGFIPPCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCX9</accession>
    <name>M5GCX9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_76440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631011.1">
        <property type="nucleotide sequence ID" value="XM_040776202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCX9"/>
    <dbReference type="STRING" id="1858805.M5GCX9"/>
    <dbReference type="GeneID" id="63691264"/>
    <dbReference type="HOGENOM" id="CLU_045011_8_0_1"/>
    <dbReference type="OMA" id="WWRQLIA"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011949">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02252">
        <property type="entry name" value="DREG-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="28591" checksum="9846F383FA12C7CF" modified="2013-05-29" version="1">MAPPIRLITFDAFDTIVRPRLPIFVSYTQIFKAHNIAVSQEAVKRAFKPSFRKIEAEYPKYGRDAGLTARNWWGKVIASTLESAGVPQELSEKALPGVVDDLMRHFGTKEGYDLFPDVLPASLKSLPNPPHLALVSNTDSRMHTVLSSLGVAHFLEPAILSSEVGFEKPDQRVWEEAVRRTGLEGLDWEGRGGVLHVGDELAADYWGAKKAGLEALLVRRHGEYSDGSRREATEDLDGVDVVPDFGGVVDYVRKRNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDM4</accession>
    <name>M5GDM4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_21617</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629432.1">
        <property type="nucleotide sequence ID" value="XM_040772469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDM4"/>
    <dbReference type="STRING" id="1858805.M5GDM4"/>
    <dbReference type="GeneID" id="63687531"/>
    <dbReference type="HOGENOM" id="CLU_031223_0_0_1"/>
    <dbReference type="OMA" id="RCMMSHR"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="11">
        <location>
            <begin position="143"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="372"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="447" mass="47525" checksum="9497AF780F1C99CA" modified="2013-05-29" version="1">MPITAIKARQIFDSRGNPTVEVDLTTELGKFRAAVPSGASTGVHEAVELRDADKANYVGKGVSKAVSNVNTIIAPELIKSGLAVKQQKEIDEFLIKLDGTPNKGKLGANAILGVSIAVSMAAAAEKKVPLYQHLAELAGVAPPYIMPVPCFNVINGGSHAGNKLAFQEFMICPTGATSFAEAMKIGTETYHTLKKVITSKYGIDAANVGDEGGFAPNVAGAEEALELLVEAIKKAGYEGKVKIALDSASSEFYKDGKYDLDFKNPNSNEKDWISGEQLARLFIADIKKYPIVSAEDPFDQDDFDSFALLTKEAGIQIVGDDLTVTNPLRIKTAIEKKACNGLLLKVNQIGTVTESIQAAQLAQSDGWGVMVSHRSGETENTFIADLVVALGVGQIKTGAPARSERVAKYNQLLRIEEEITEVSGKAPEYAGLSAFAAGVNPPALLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE11</accession>
    <name>M5GE11_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629772.1">
        <property type="nucleotide sequence ID" value="XM_040768360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE11"/>
    <dbReference type="GeneID" id="63683422"/>
    <dbReference type="HOGENOM" id="CLU_707923_0_0_1"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="43963" checksum="34DDD4C1B08A57B0" modified="2013-05-29" version="1">MSTRTAINNLPSELLGLIFQFAHTQAVEDLQDAWLANAKNMAVQFAASTRRTSTKQPNDTASRNLALLVHALYSVCTLWKDISTSMSALWAVISLAPRFNLPCTPQRFLELSAGNRITLVMEVNAVNTKHGSLMLRTMDQCDALQRVFCLYLRIATRESYLDFIEHRFSSLEHLHLCAPYFPWAPELEDWAWLGAHSLTLISFDMWSGGGWTIYQYPIPFPRLEQVDVHSVGDYSLRALEAIALVSQEMFFSGLLSTNPTNPVANLRQLCLEGYVDYNVLNGILESSPKLESITILSGALREDIFDGLIRRLHQPSRVLHAPSVRSFRIVGGTLLRTNLQVFVNLCGSISLPNVNTLTLERVRFIQLEDEDYSLPLHVPLCLQVHMIDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEB6</accession>
    <name>M5GEB6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_50483</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630027.1">
        <property type="nucleotide sequence ID" value="XM_040774990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEB6"/>
    <dbReference type="STRING" id="1858805.M5GEB6"/>
    <dbReference type="GeneID" id="63690052"/>
    <dbReference type="HOGENOM" id="CLU_036094_1_0_1"/>
    <dbReference type="OMA" id="WRGWAKA"/>
    <dbReference type="OrthoDB" id="5197598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="450" mass="48270" checksum="09A0373D92146956" modified="2013-05-29" version="1">MPWPGVTRRKSRSEGKRLTILGRSVLLLGSLLAFNGLCWVLAGILFGRKESTREVLSLCVLAWTYGLRHALDSDHISAIDNATRGLLALGQQPVTCGFFFSLGHSTIVIAVNVAIAISTTVFEHLDGVGNVGGIVGTAVSASFLFLLATANSIILYTTLRRKRARERQIAAGLPVEPLEHDIEPIQNRTLMMRILGPVMRVVDKPWKMYPVGVLFGFGFDTASTIALLAVSAIAKSAAQGNIVILPFLFTAGMTLVDSIDSVLMLYSYALPSRHTAEGALAFFERKEDQAQDLSQPQQESIDPISLSEKKGEEFVTPLVTEAPPGGDEIVAPTPAQVMNTHLEHNKATTLSSLSIILTLLSILVAFSISLIEIMGLIGDNCGPCQDAANAPDGGGLAGSWWRAWDAANDASGYIGASIVGVFVCIVLVYFGGKWAYQRSTRKAAGQSRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEI2</accession>
    <name>M5GEI2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_115482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630172.1">
        <property type="nucleotide sequence ID" value="XM_040770012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEI2"/>
    <dbReference type="GeneID" id="63685074"/>
    <dbReference type="HOGENOM" id="CLU_743987_0_0_1"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="297"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="372" mass="40952" checksum="E4A62D4DC5153A88" modified="2013-05-29" version="1">MLRRDSKPTPAIPPTIAPSDLVGLTGSYLQMRNVPQNVKARIEHNMGRGIAQELKTYHHPGMAEEQGIQQPNSSTIALALEDLVETGTVSDELKAAFEETTSPFSGERCGAEPEEDAVIRDFFDQYTNEGRSDLMMSPHELLYPWNIGITPPSHVLPSAPAPAVRSAALPPPAPAASSQTSSRPGKGRTPSGTHSDLVKQDRPSPSPSASASPMVSTTPVSDGRVSRPSRGKRRIALDAPIQSRTYHGASRTSVRTLPRGFEKNLEPDKVAGFKRAIEAVEEGDDEEDDRDLIENVTSKVMQKRVKNTLAARKSRARRAEYLETLERRLADKDERVQELERVLMEKETEIQVLKAILYEDENNDEGESEIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEK4</accession>
    <name>M5GEK4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_46282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632386.1">
        <property type="nucleotide sequence ID" value="XM_040774693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEK4"/>
    <dbReference type="STRING" id="1858805.M5GEK4"/>
    <dbReference type="GeneID" id="63689755"/>
    <dbReference type="HOGENOM" id="CLU_150144_2_1_1"/>
    <dbReference type="OMA" id="YTLWIIV"/>
    <dbReference type="OrthoDB" id="311279at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="9855" checksum="0753F6CBF6B68E23" modified="2013-05-29" version="1" fragment="single">QGISDKLVGGFFLFVASFVFVYYTTWAIFLPFLPPSHPLHDHFPPREWAVWGPALLLVLGVTAIGLFIGMVMYREGQKKRSKAAMKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEM8</accession>
    <name>M5GEM8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_46743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632441.1">
        <property type="nucleotide sequence ID" value="XM_040774724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEM8"/>
    <dbReference type="STRING" id="1858805.M5GEM8"/>
    <dbReference type="GeneID" id="63689786"/>
    <dbReference type="HOGENOM" id="CLU_000288_57_25_1"/>
    <dbReference type="OMA" id="GHISGCV"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
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        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="275"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="323"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="566"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="634" mass="70862" checksum="1EEA0F9314DD777A" modified="2013-05-29" version="1">MDIIPDFLQRPIVRPASSQSSFDNEPVAGPSNGHYIANGHTETNGFRVSIRRVEPPGRGMYAGSSVDREEFVRLVLQGLRDVGYVEAAATLEAESGYTLESSSVADFRECVLNGQWGRVESSLTSLGVVMEEDLRVSPAYVRFLVCEQKFLEYLENRQLDVALEVLREEITPLQQEPQRTYALSGLMMCDPKDLHTRAQWDGAAGRSREVLLNRLQRYIPSSIMIPPRRLETLLNQARQLQSNACIYHTSTRPFSLYIDHQCDRTEFPLHTTMILADHQDEIWHLAWSNDGTRLATASRDQSVIIWRIGVSADPNDCALEQRLREHANAVSFVAWSPDNNVLLTAAEATIKMWNPKTGLCIKSILGHEDTVCSLVWRRDGSGFISGGMDQKILFWDKDGKQLDSLEQIPIRMSSVAISPDERWLVVAGMLANPTKTLVRAENGNGAQNPALTGKQTRFTVYDLRTKEEHASIDMTGEITSVTISSDSNFGLINHSPDGVMLWSLEEPKLVRKYAGQKQTKHVIRSCFGGPGENFVLSGSEDTNVYVWHKESGTPLEILQGHGQGSVNAVAWNPCQEAMFATCSDDHTVRIWGKDPPGFITSITESTTEDIPPQVSTLSRDPPTLRWDDAREMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF61</accession>
    <name>M5GF61_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_115179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:K48-linked polyubiquitin modification-dependent protein binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="6">
        <location>
            <begin position="251"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36274" checksum="DBA7337C2B4E8B21" modified="2013-05-29" version="1">MSDRETLLSFGFAPERVDWALKATSNAGLQPALDHLEQHQDDPVPDLTAVIPGKGAAQPEDDDEDDEATAIAASTGAEAKSIKCSECGKIFKNTALANYHAEKSGHDQFEESTEEIKPLTEEEKKVKLQELRERMAEKRKVKDKVDAEDQRKNEDIRRKAGRDAGYIKEELRAKETIKAAEQARRDKIEDAKAKAAVKAQIEADRRARAEKSAREKALREGKVYDAEAGAEHAAPAPAAASASASMGMKSKDYPETRLQIRLANGGPYTTTLSSDAPLSEVAEFIAAQNLAFDADRVTLSTHFPRKTFTQADMRRTLRELGLTPSAVLIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFB9</accession>
    <name>M5GFB9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFB9"/>
    <dbReference type="STRING" id="1858805.M5GFB9"/>
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    <dbReference type="HOGENOM" id="CLU_016261_0_0_1"/>
    <dbReference type="OMA" id="GKMLYNA"/>
    <dbReference type="OrthoDB" id="2154253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="22"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="42359" checksum="92BD8B626D98E836" modified="2013-05-29" version="1">MNVVVRQIIATEQANSSPRKVVLIASKDFQHGEEIYKEHPVIAQLDIDLEGTAQYCSHCFRALQSGKSITPPEDLLGSAYCSTECQMISDTQSQNLLFGRGPLVPNEAVTGQLERTEAAEAERRAYQQAFVDFLKACGWTQVLLVGRFCARHVSEEVKKLAPLPASLVERSALPEPITPSPEYTFYDHVERLKFLEIQPTEMVMLEHNLLQDVLKKAVAGLEEVVEINKYLAMKGRIAYNSIGVAFDGGRDDRADPKGRVETWEWSRTPVGTERQIGSALYRVSSYLTHSCSPSVRLCFKGTNELHLIANRAISKGEHLTMSYTSIEAKNGEAPEVARRQRRIRLARGWRFACECEACTGKKSEVVGTMTAPDVILEKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFX2</accession>
    <name>M5GFX2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_99096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631417.1">
        <property type="nucleotide sequence ID" value="XM_040777563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFX2"/>
    <dbReference type="GeneID" id="63692625"/>
    <dbReference type="HOGENOM" id="CLU_758685_0_0_1"/>
    <dbReference type="OrthoDB" id="10306720at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="234"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="365" mass="40749" checksum="F056FDAB5604DB63" modified="2013-05-29" version="1">MYNEQYFEEEENSSVPTEPSVGYNYVAWPQQVALSVNVSLPVLWVQTGSIEQASYLTAGQEPGPSFPVYPQAPTSTTHGGPPGVYEPFAQYSATFATGQAIPISPQAHGNYYLPAGSAYLPQASTWSGSQIITPSQAQAYLKEEGSDGGSAQSYRSSSEEGTLDSKGKAVSTSPTNQFFAHAPPENWQTRGDSTILHMYRPGTASASPKNTSALVAVFKQDPEGSAKLRTPNTACYHCKHRRIKCEDKIYTKAGRPFCSACVQRQGPCYWPPRYHPYLQADYLTVRRSELMQEDPQRYAALVSQGKLDDQLLGEFDASKCPKPISWTWRYNEHTGRKEFDNVPPTGKEKTPKRRKTLDDYWWDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFY2</accession>
    <name>M5GFY2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631442.1">
        <property type="nucleotide sequence ID" value="XM_040771863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFY2"/>
    <dbReference type="STRING" id="1858805.M5GFY2"/>
    <dbReference type="GeneID" id="63686925"/>
    <dbReference type="HOGENOM" id="CLU_1503385_0_0_1"/>
    <dbReference type="OrthoDB" id="3364107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19817" checksum="0F78BB95C9E6CB75" modified="2013-05-29" version="1">MSFATFRRFALIAVIILSIIELGIAASIKDKLGIATGVLSSVGIAVSLFMEQSEEPAVINWVGVEVFWTGLLWVLWIATAALGTTNSSGCSSFFHFYQGVYWSYDASFCNKFHVIQAFSFINAFTLMAIFIWNLKIAVSAHSQGHARVWRMPAAMYDPRRPYGNSGAMNGGKEERTEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG21</accession>
    <name>M5GG21_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631622.1">
        <property type="nucleotide sequence ID" value="XM_040767953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG21"/>
    <dbReference type="GeneID" id="63683015"/>
    <dbReference type="HOGENOM" id="CLU_1713179_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="17004" checksum="A8109385BFA8A8BA" modified="2013-05-29" version="1">MICDHPAMDLVDIKQLSGLLISSLLHSAPPVKTLYCVLGIRSFERKPTTPTVRRTTPRPSSLPDSPPQVTNIGGVHYVYRKFCISLRFTLSRFPVAIRSDRDPADVLFHRPSLLLTSYCLVSTCGMKVALHQLGLAHLNSATSRFESVFLVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG58</accession>
    <name>M5GG58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_114230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631807.1">
        <property type="nucleotide sequence ID" value="XM_040769780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG58"/>
    <dbReference type="GeneID" id="63684842"/>
    <dbReference type="HOGENOM" id="CLU_855267_0_0_1"/>
    <dbReference type="OMA" id="SKEYHRS"/>
    <dbReference type="OrthoDB" id="2124108at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="299" mass="33606" checksum="D97F06D693464B03" modified="2013-05-29" version="1">MDFFADLQIADEQDETRVSREDRINRAFEESKRSYKDERVLTEPGWFNSDLSVKERLASSSRAVREVEWSVQQLYVQRKYADCLRMTLEFLDALDNLADNSAGAPDEPKQELRRRELLDIGMRCAFKVHDTNTAKTLADRSRPSWKTNAGLASAAAEAYVLASEPYQAITASLDVIDFRGPLSPYLAPLCRALCQLEPSWPEAAGSEDRKHAAQQLLAVVEALEQRAQAGVSLALSAKQTSTRGGTVLPEVPKPTEEDIHRWTQALSIEESDALRLTKLCCHHDEAQEEKDTIRSVRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG77</accession>
    <name>M5GG77_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_76031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631902.1">
        <property type="nucleotide sequence ID" value="XM_040776174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG77"/>
    <dbReference type="STRING" id="1858805.M5GG77"/>
    <dbReference type="GeneID" id="63691236"/>
    <dbReference type="HOGENOM" id="CLU_040959_2_0_1"/>
    <dbReference type="OMA" id="CIEMGLY"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="393" mass="43564" checksum="C16885325A2B4831" modified="2013-05-29" version="1">MHSTVLEAPHPPQSSKKSKSKAAPTTEALLAKAQELVVQCEYELGRQFVDRVLERDSENVEARELKGVVEMEAGNPERAKGIFLSLVPPSPSAPSPAPPSVHLYLAQLLADDDPRAALGQYRTAVDLLVTRLGGKGKGKTEKSLEGLEEEEEEIRRMVVRVCCSMVDIWMTDLCFEPEAESSCEEILRHALDTDPENTEALLSLASVRMSQQRPDEAEQCVHKVWSTWEGIAADSPSHPAPPTLLSFARLCLELNLFALALASLSRTLEMDDQEVEAWYLEGWAFWLMYQDEGSAVNLTQSAQDGEQGEKMTKEDMLRDARDCLDTCAMLHQAQEHPDEQILLHVKELLGELEALGVHAALPEEEGEGEQLTGDGDDGEWVDEDDEDKDVDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGF3</accession>
    <name>M5GGF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632282.1">
        <property type="nucleotide sequence ID" value="XM_040771714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGF3"/>
    <dbReference type="STRING" id="1858805.M5GGF3"/>
    <dbReference type="GeneID" id="63686776"/>
    <dbReference type="HOGENOM" id="CLU_007884_14_0_1"/>
    <dbReference type="OMA" id="DDTVYAC"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="382" mass="40491" checksum="70A3B00847EE977F" modified="2013-05-29" version="1">MSRSIVIIGGGIIGTSTAYYLTRHPAYNPANVAIHIVEASHIAAGSSGKGGGFLAEDWHQPYTASLGRLSFRLHEELAREYGGDQLWGYRRVKTLNLEINATGPASKKTKSLDGSEWLGKVEDISVIGDVRTTAQVTPYPMTTFLADKCREAGVQITIALVDGIEFADDGSPRGLRASNEQGETFAFPATDIVFAAGPWTGTLAKKLLGRRAGAAGGIVPSEASTSIIMRPPSDATIPPQALFSSIRMPDGRYGSPEVFPRPDGTVYICGAGTGDGVGLPTRAKEVGPSTRAVERLVEYMNVISPTRFKDATIEVQQACFRPNPPRGGNPVIGQLDKGLWVASGHNVWGLNHGPGTGKCMAELIYEGRARSADISGLAPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGG2</accession>
    <name>M5GGG2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19932</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632327.1">
        <property type="nucleotide sequence ID" value="XM_040771726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGG2"/>
    <dbReference type="STRING" id="1858805.M5GGG2"/>
    <dbReference type="GeneID" id="63686788"/>
    <dbReference type="HOGENOM" id="CLU_014658_2_2_1"/>
    <dbReference type="OMA" id="GIVCAFD"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000050">
        <property type="entry name" value="Asparagine synthetase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="14">
        <location>
            <begin position="2"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="11">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="374"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="13">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU05433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="589" mass="65569" checksum="B7D0107C7C0DBE93" modified="2013-05-29" version="1">MCGILAIHGLDNPASQRAHAIAMSKRLRHRGPDWSGCFVGKDSILVHERLAIVGVDTGAQPLTNKSGDLALCVNGEIYNHVALRKGLKMPHKFKTHSDCEVLLYLYTEHDTGLCNMLDGMFSFALIDNSRTPSRIVAARDPIGITTLYQGWSSSQPGVVFFASELKALADDCDKIISFPPGHVYDSATGKTERYFNPTWWDTDSTKPVPTTKVDLKLLRETLEAAVRKRLMSEVPYGVLLSGGLDSSLIASIAARETDKVAQELMQRRQRHLLVNGSSTPTHGPEEYPIASWPQLHSFSVGLPNSPDLLAARKAAAFLGTIHHEYTFTVQEGLDALEDVIYHLETYDVTTCRASTPMYLLSRKIKAMGVKMVLSGEGSDEIFAGYLYFHAAPTPDDLHVECVKRVKNLHTSDCLRANKSTMAWGLEARVPFLDKAFLEVAMNIDPVEKTFGKKEYDEDGRPKMEKYILRKAFDCAPDGKAYLPDSILWRQKEQFSDGVGYSWIDGMKEHAEGLVSDEAFAKAEQRWPVDTPDTKEAYMIREMFERLFPTEAAASTAVRWIPRKDWGCATDPSGRSVTIHKAAYDAPEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGJ3</accession>
    <name>M5GGJ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">DNA damage-binding protein CMR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_46443</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632482.1">
        <property type="nucleotide sequence ID" value="XM_040774703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGJ3"/>
    <dbReference type="STRING" id="1858805.M5GGJ3"/>
    <dbReference type="GeneID" id="63689765"/>
    <dbReference type="HOGENOM" id="CLU_017019_1_0_1"/>
    <dbReference type="OMA" id="DPNTLYW"/>
    <dbReference type="OrthoDB" id="9890280at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000001">
        <property type="term" value="P:regulation of DNA damage checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="563" mass="63127" checksum="F5D933A3448AA7E8" modified="2013-05-29" version="1">MSTSERERLANIAHNKAILAQLKLDTAGEGFFGPKPAPPIKEKKAKPVQTLRKRRSSPVLPERVMPTRSSTRLKRAAFEDPNESPDAKKRRLESEAEARRLQEEEAMAEIERQIAASRPRHQDLDLSTMGIKEEEESLASLSSTFRAVDVDGAKRSYLGDVGVDEDVKGDPGMEDLKERFAKLVVKSRAKVTEDRIYSAVYHPERTKDLIFFGDKHGQLGIWDAQAPPDEPADEEDEEAKETAEGGKYWRLQPHWPATSKSSISCVKIDPLNAQCMYTTAYDCTLRHTSFESSVSREIFSLEKTLLSTVDITPSGQELWISDVQGGLTHLDIREPRYSAVRWSINEAQKIGCVSVNPTSPHLLLTASNDRTIKIWDSRKLPHLLQPDKKPKLPPTPPHYDDLAPLYSAEQGKKGYGLLKAQFEHRASASSAYWDPSGRKIVSTSYDDHLRVWDLKGESLAREAPFQVFKPRRQISHNCQTGRWLTILRAQWSPNPDVHPHFTVGNMEHSLDVFSHTGEVVAQLYDSTKITAVQAVTCSHPSIVERAVSGNASGRCILWAPGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMX5</accession>
    <name>M5FMX5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_25719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JH795946">
        <property type="protein sequence ID" value="EJT96455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623353.1">
        <property type="nucleotide sequence ID" value="XM_040774271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMX5"/>
    <dbReference type="STRING" id="1858805.M5FMX5"/>
    <dbReference type="GeneID" id="63689333"/>
    <dbReference type="HOGENOM" id="CLU_060828_0_0_1"/>
    <dbReference type="OrthoDB" id="3261737at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="44138" checksum="71825439086B9130" modified="2013-05-29" version="1">MSNELNNILSLVTNGTYEGIAVGSDRYPGTTFIDHMLRYEADPDCKMLVLLGEVGGIEEYRVIQAVKSGKITKPIVAWAIGTCVKMFTTEDQFGHAGSMANSDLETAAAKNAAMKAAGFIVSSTFEELPAVLTQTCNKLVKNGIVKVVAEREPPELGLIRKPAAFISIISDERGQELMYAGLRISDVFKENIGIGGVVSRLWFKRRLPAYATKFIEMVLMLTADHGSAVSGAMNSIVATRAGKDLISSLCSGLLTIGSRFGGALDEAAAIGIGHKIKSVNNADLRVELIKEFVIKNFPNHTLLDYALAVEKVTTAKKDTLILNVDGCIAVCFVDLLHDSGAFSRDEADEYIKIGTLNGLFVCGRSIGFIGHHLDQKRLRAPLYRHPADDIFINMQDMSQPRVLAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FMY8</accession>
    <name>M5FMY8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795892">
        <property type="protein sequence ID" value="EJT96520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623418.1">
        <property type="nucleotide sequence ID" value="XM_040774259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FMY8"/>
    <dbReference type="GeneID" id="63689321"/>
    <dbReference type="HOGENOM" id="CLU_2671013_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067084" evidence="1">
        <location>
            <begin position="20"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="75" mass="7541" checksum="32437480BE889E52" modified="2013-05-29" version="1">MRFMMSLAFLLFATSSAFAAPTPLRPDEADVALVDRSLSGGVKLVGAGLLGVAAGAVDLGVSAVEDVGHVIGKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FND2</accession>
    <name>M5FND2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">beta-glucosidase</fullName>
            <ecNumber evidence="3 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_112184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 6"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624138.1">
        <property type="nucleotide sequence ID" value="XM_040769363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FND2"/>
    <dbReference type="STRING" id="1858805.M5FND2"/>
    <dbReference type="GeneID" id="63684425"/>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="OMA" id="HYHARRI"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="410"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="852" mass="93074" checksum="09944A18B4D638CB" modified="2013-05-29" version="1">MAPSDFANADITSLVNQLNTEEAIALTTGVGNWFTAPIPRLDIPGINVTDGPNGARGRKYFLGTPAKCLPCATALAATWDPELIGDVAALILAPECKLKSASVLLGPTVNIQRNPLGGRSFESFSEDSWLSGCMAAEYVKRLQGEGVSACIKHFVGNEQEQERKGSDSLISPRALREIYLYPFMLAQKRAQPWSYMTAYNRINGTHCSEHPWLLTNVLREEWGFDGCVMSDWHGTYGVPEAYHAGLDLEMPGTDGWRTASKVIRSIEATKLTLPIVKERARAVLKLVQRCAKGAPEILDGDQQERTRDTDAEKTLMRKVAGSAIVLLKNEGNVLPLEKSKIKTLAIIGPSAKAAYFAGGGSASLKASYVVTPYEGILAALPEEVKVVYAEGCQGHRRAPPLTGRELITEDGRAGLNATFYHKRDSEGNYSAAVEHFLLDNTDTLLNDSDIFFSADEWYLVLWGKLRAQERKTTFRFGLSVAGRAKLFVDDKLVVDNWTWQRRGDSFFGDGTEEEMGNFEMLSGKAYDIRLEYSNLTGPAEGDEKGVPNPHAGMRLGGYPLLDEEQGISEAVALAKEADAVVVVVGLNGEWESEGYDRKTLNLPRRTNDLVAAVAKANPSAVVVTQSGSAFTMPWVDSVNALLHTWYLGNETGNAIADVLFGKVNPSGKMSLTFPKRIEDVPSYLNYGNQNGRVKYAEDLFVGYKHYHARRIEPLFPFGFGLSYTAFKYSGLQISPPSSCDASFTASVTLTVTNTGKLPGSEVVQLYIAMPSGNLIHPHLALKGFTKLHDIPVGKEATATLMLDKYAVSYFDDVAGKWKVDAGQYTVFVGSSSSHLPLTAVLPLKKLFTWSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNV4</accession>
    <name>M5FNV4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_120013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623481.1">
        <property type="nucleotide sequence ID" value="XM_040770915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNV4"/>
    <dbReference type="STRING" id="1858805.M5FNV4"/>
    <dbReference type="GeneID" id="63685977"/>
    <dbReference type="HOGENOM" id="CLU_017236_0_0_1"/>
    <dbReference type="OMA" id="WERICTH"/>
    <dbReference type="OrthoDB" id="2117591at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="547"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="843" mass="91868" checksum="57F4116241A6BD43" modified="2013-05-29" version="1">MNSSYTSSSQNSEMRTPHFIAAAKAQLRRPAVQARISSAKSLFSATKDYLAQKDYRAAYADVSGRMKSAVSSARDLAGQLARDDDAPENESVQGWVVRKRQTWDEWTRDRRRRRQEELRGTERVWLFPGWAARCTSHSRTTASQKKDAQEPFDVELKVSGYFLSMRPPEQATRAQRAFMRLARSFSSLPRLPTPGSGSGSESASLRSFEGGSTPPSGTASPLMSPLLRAIISEEPEDADLINLDSPAGASKDDGGYFTSNNWVGKDPLPSPSQEPLELDLLTPTPTSAGALVLEHENDKTTPSISLSPVDYSERTAPPPIPLKPASLSSIPSLSLPKPLNPTPVHHAHHVHSPRAPSPLSSPSLGPTRSPRLGPHRQPSPSLGPTRKSTSISSASFADLPSSELRTLHANLEARLQPFWASSLSLRKVKLTISLPPPPPATEKSDSPSTVLANLSSSKAPIKLLEKEVTTNSNGYFDERLRVPWTTLTSALRKAGVDLSRLSNIEVRAEVVPLPPIPSFAPDPTQAPHPTQQSPPLEYALPPSPALRVISDIDDTVKHTGVLLGAKQVFHNVFVRHLDELVLDGVGEWYREMEQWGVGFHYVSNSPYELLPVIREFFEVAGLPQGSIKLKYYSPSAVFTGLWDSAADRKRHGVVEVLDAFPSSRFILIGDTGEQDMELYVQLAQERPWQIVGIFLRDVTPPAWTEDGEQREERRPFRRSMSGMSLASTASLSASLPVGGSPLSSPVLEAYQPRRTHTASSTPPSPAAQPTPQSPAMPSSVAYLSQSAAQQPAPITNAKAGEVWRARLAAARKAVPEGVGFTIFRSPEECGEWRGIVARYAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNW1</accession>
    <name>M5FNW1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_96953</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624888.1">
        <property type="nucleotide sequence ID" value="XM_040777411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNW1"/>
    <dbReference type="GeneID" id="63692473"/>
    <dbReference type="HOGENOM" id="CLU_004965_1_1_1"/>
    <dbReference type="OMA" id="AMIWPAD"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="435"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="481"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="587"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="626"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT97990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="797" mass="89487" checksum="3EA9E9C2A367B8B2" modified="2013-05-29" version="1">MGRANSTLPPYYNNLLRNGYGYLDTRKRTAKHFGHRNSIELIPSLSLEDTPVPQAGQNAHGPVPSQQSASSLRSSKKGGPLALKMETSLEEASGLDFDTPELNIELDDDSPYPEVRATVSNTDDPMMPTNTFRMWFLGILSTAILSIVNQFFSMRYPRIGISVIFVQLLTLPIGKFLAYALPKKQFRIFGYVCSFNPGPFNIKEHALICVMASFGGAAYATEIVATQRVFYNRNWGTLYEICLVISTRFLVWPASMVWPGILVTVSLFTTLHEPSSKTTDRRMSRHKFFYIAMACSAVYYWFPGYIFQALSMFNWVCWIAPDNSVVNSLFGYTSGLGMSLLTFDWNMINYVVGPLYTPWWAQVNTYVAGLLLYWIVTPICYYLNVFYSAYLPISSVYAFDNTGSTYIPEAITVNGVFNETMYEAYSPRYMSVTFALDYGLSFALITAVIVHTLLWHRHDIVRQFRTSLSEEDDIHARLMKVYPEVPDYFALALVTILVWPTELPAWALIIAVIISLVYLVPTGIIVAISNFDIGTNVISELISGYLLPGRPAATMIFKTFGLMTTQQALGFVSDLKFGHYMKIPPRMMFSTQIIATLLSGILVVLVQDWMFANVPGLCTPDQVDNFICPGIEIFGAASLIFGTIGPKRFFATGLYTPLLWCFLIGAILPVIFWFLAKRYPNSGFKWVNIPLALGGLGAIPPASGYNYFSAFLVGGLFMYYLRRYHFPWWAKYNYVLSVALDSGVAITALLIYLCLYLPGGVVELVWWGNTVFMQNLDGVFGAWKQLPLGGTFGLTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNZ0</accession>
    <name>M5FNZ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SET_SETD4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
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        <property type="entry name" value="SETD4_SET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF47">
        <property type="entry name" value="ACTIN-HISTIDINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
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    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT96653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="413" mass="46605" checksum="D448B4F825C4C0DF" modified="2013-05-29" version="1">MASLKVAWAKTEGEDRGLVALQEVRASQSLLSIPTTALLNARTLAAFFPLNSVPSSNASGSILNAVQAVSLYLAAHRQDPHCHWAPYIRTLPADFPDHPVNVFLVHQHHPDKPSHDLWDRFAVLSSGPPTFLALLNEVVARCKQDLSAIRTYLSTHRNLFRLPGDFDIKDLLWGWLNVNTRQVWMELGLKREDNLTLAPIFDMCNHTAGSGGELKPSPSGRELSLCVPYKLSKGQEVCIQYGVHSNVQLLVEYGFVLDLRRCDVLEVRVADLVLPMLQTEGNREQEMLTALQANGYFIKDWALHVYPEPAAPSYGLIVALRLLHSAAPPDDYLHWFEILWSGQFSEKYPLIDERVKRTLSDMCLQILNRAEHHLDVLSEVSSFAHDVRTLWEEERDVALAVQQSLLHDLLEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ70</accession>
    <name>M5FQ70_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_85498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ70"/>
    <dbReference type="STRING" id="1858805.M5FQ70"/>
    <dbReference type="GeneID" id="63691799"/>
    <dbReference type="HOGENOM" id="CLU_055868_0_0_1"/>
    <dbReference type="OMA" id="FPTWREY"/>
    <dbReference type="OrthoDB" id="110024at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="342" mass="38093" checksum="48EA2658F6A08F02" modified="2013-05-29" version="1">MSTSVSSIFPSGLPSSLYTVLHLDTHASSAQIRGAYRTLALVHHPDKHATASQEQKDEHALVFQQVGFAYVVLSDAGRREKYDLTGSVEELSDLGGEAGWDAYFEQLFEEVTKSRLDEDKVLYQGGDEELEDLKRAYVEHEGDLPSILDSIPHSNYTDEPRLLARLKLLVADGTLPSFPAWEKTLADKRAARERKKQGKAEEKEAEEMAKELGVWDEFYGTGKKGARQGNGKGKGKNGEKENEEEDTSALQALILKKRQNAGNFLDNLAAKYAQPEKPNGNAKGKGKSKKRPAPEEEEEESPKKMKKDVHDELDGMDDELFRKLQEGMFGKREGGKKGRKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQU2</accession>
    <name>M5FQU2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_24861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624846.1">
        <property type="nucleotide sequence ID" value="XM_040773888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQU2"/>
    <dbReference type="STRING" id="1858805.M5FQU2"/>
    <dbReference type="GeneID" id="63688950"/>
    <dbReference type="HOGENOM" id="CLU_029381_1_1_1"/>
    <dbReference type="OMA" id="MRQTGFM"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="42"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="410" mass="44216" checksum="D5C88CCF6B6F21B8" modified="2013-05-29" version="1">MSPIPTLTDLEAARAKVANELSVDVLKGVDLHKTELALARNFTSDTITYPTDGMIAYAMKASRGDDVFKADQCTVALEAHIAQITGKEAALFCASGTMTNQLAIRTHLLSPPHSVLCDARAHVHRNEAGGIAHHSQATTLPVMPENGHHLTVKDVKAAAILSEDVHLAPTRLISLENTLNGTILPQDEIVAISQYARSSGIKMHLDGARIWNVAAETGASLHELCEPFDSVSLCLSKGIGAPIGSMLVGNREFISRARWFRKMFGGGWRQSGYLAAAAAYALTHNFPLLSGTHALARKLEAGLRDIGVGILCSGTNMVFFDARSIGVNYDELVKRALALPEPLYLGGSRLVIHYQTSEKAVNDLLDLIQVMANEKRAEGFVPGVLEQQPADAYYPKMKEVFIRSGTKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRF3</accession>
    <name>M5FRF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625136.1">
        <property type="nucleotide sequence ID" value="XM_040769193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRF3"/>
    <dbReference type="GeneID" id="63684255"/>
    <dbReference type="HOGENOM" id="CLU_2333578_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="10809" checksum="F5517C47E976682C" modified="2013-05-29" version="1">MSGPTDARSPAHPAFASKHKRRHIPWALGTDCPHSRLPTPGTATPAGGDITLRLHAYGRSPERQWLTQHQQVLPAGGERQVLSFRLPVAKPQQPRPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS18</accession>
    <name>M5FS18_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_102189</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peroxin-14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624807.1">
        <property type="nucleotide sequence ID" value="XM_040767615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS18"/>
    <dbReference type="STRING" id="1858805.M5FS18"/>
    <dbReference type="GeneID" id="63682677"/>
    <dbReference type="HOGENOM" id="CLU_045718_0_0_1"/>
    <dbReference type="OMA" id="YNQWQPP"/>
    <dbReference type="OrthoDB" id="5549158at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="13">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="271"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="163"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="389" mass="41279" checksum="30A308234244BFE9" modified="2013-05-29" version="1">MSDNSGSSGSSNPAPTLPSIPSSSTPRQDLVQNAVTFLLDPSVQSAPLAKRIAFLESKGLSSSEIETALHQVSSRGSTAPTHAQAGTGRVTYNPGGSGYGQGTAAGTHLQQMVAPQAPARDWRDYFIMAIVSGGVTFALVSLFRRYVLPHLLPPSGPAFQQTSDALTSAFDSLAEQVRKLEEAQEKEKTDRENEREEVEKVLGEVREGVKDVREGEERAREEWEEVRREMEGIKELVPKMLERLTSNQTRTLTELQQELKSLKLLLLNRTPGAHLPSAPSPSSSPAPSNATGHARSSTLVTGSSNTSSLGTSTPATPVPLQQASPFLSGFGLGGTGRPSIPSWQLRPTAGQEAEVSGSSGSGSTKGKEVLVSEEASVPEIGEREQEAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS83</accession>
    <name>M5FS83_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624917.1">
        <property type="nucleotide sequence ID" value="XM_040773739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS83"/>
    <dbReference type="STRING" id="1858805.M5FS83"/>
    <dbReference type="GeneID" id="63688801"/>
    <dbReference type="HOGENOM" id="CLU_1865062_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="137" mass="13922" checksum="DB29760BD85DE2BD" modified="2013-05-29" version="1">MINLPIALVALAASTNAQRYYNNGYNNYGMSRGARIGLGIGIAVAFLIFLCLLISCCMSIRRRRAATPGLGIGAPAMGTVGGPGYGPAYGPGIGGGKRFGFGQGRFGRGGIAKPANTYQPAVGAYAPVSLSGIVGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSA6</accession>
    <name>M5FSA6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624952.1">
        <property type="nucleotide sequence ID" value="XM_040773753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSA6"/>
    <dbReference type="GeneID" id="63688815"/>
    <dbReference type="HOGENOM" id="CLU_110355_2_1_1"/>
    <dbReference type="OrthoDB" id="5519740at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="15"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="99" mass="11053" checksum="D42A70D7D9BFCDFC" modified="2013-05-29" version="1">MSKVFFVYAPDFTDEAAPERRNSVRAEHLKVAAARTNTLLGGPMVTEEGKMTGSTMFINADSEEKVRAIVESDIYYKSGVWDPANIAIWWYRPAGPPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSR9</accession>
    <name>M5FSR9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_23000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627438.1">
        <property type="nucleotide sequence ID" value="XM_040773045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSR9"/>
    <dbReference type="STRING" id="1858805.M5FSR9"/>
    <dbReference type="GeneID" id="63688107"/>
    <dbReference type="HOGENOM" id="CLU_005996_3_0_1"/>
    <dbReference type="OMA" id="CLASIGK"/>
    <dbReference type="OrthoDB" id="2016913at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040520">
        <property type="entry name" value="Importin_rep_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18806">
        <property type="entry name" value="Importin_rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="6">
        <location>
            <begin position="115"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="994" mass="109826" checksum="4A1A5615080CE09C" modified="2013-05-29" version="1">MSYQGNVLPVLSPDEVEHTVSLIQQLYSPSTDAEHQQSLAKDLVSIQKTQEAWGLIIPLVQHPDPTVEFVGAQIAQIKISRDWETFPVDQAIALKNTLLDLAGRSCSNGTSRVAVRKLFVAITNLAFRIVPQRHSEWPDWILDCVTSLSGQGATAEYILAFLGIAAEEALRTDFLATEKMTFHQSLTDSVHLMLEAVKKSCTDPTTSESEMETALNCLQLWVEWGVPVDDLTDSIPFLITLLSSRETFIPASDVLQEILYASPLSDGKGSKTLTEPLLQWLETLGESILNEAIESGTPDDNAHSLCKLLIAMEEHSPDWLAARLGEPRITCFLNLVLAFTNYPGVYLIDEEESATALPFWYLFQESLSVSAFADSPLSPQWEMAKSLYTQVVVVLRKKAAWPTEHLMKDQVEKFRSYRRDVGDALMNAYYVLREPMMGGLIDLLYEELQQENHDTPGYWEDVEATLHVIKSIQEAVSVEEQEQLARLWSQDVLDRICASPDPRVRQTMLGVISAYSTWFSQKNPSTIMAATLFVLNSLNVSSVSFQAANALKVLCDNNRVVLAQNSLSWFSDLYGELDTIQDTEKGTVLQSITSVIQALPVEQVVEPAGQVVSPLVTKLSEALSIASQYPDVARLVCINQLRYIAACAKGFTSSQDLLTNDLLSATEEEEARRRESMHTVRQDPRLIQLRANIQDGISGCFTLWSSNADMASALSELLRAMTGLPSEETLISLDPGPLLVLVCGAAERQLSATWLSLAQILITQLDPKKFLWIRPSADPEALALVREATLSLLNTAVQVLGQPGAMEANTDLVQDFFGSCMNAIAMHFIEEMYKLPPGAVNSLVCAAISAMALPERYCIVSGVRFLHTFIDQTLRVCPDNAVLLNQVHGFAMLHVILHGIAFRAPRSTIPNLSDLLAILSSKFFEDTQASMRVILFADDFSYPKGTDKAKKAFIKAVARHRRVKKVKEAANDFALVVRGLEASGFGYASSAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FST5</accession>
    <name>M5FST5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutathione-independent formaldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_117057</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627463.1">
        <property type="nucleotide sequence ID" value="XM_040770309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FST5"/>
    <dbReference type="STRING" id="1858805.M5FST5"/>
    <dbReference type="GeneID" id="63685371"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OMA" id="PVMKYHR"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08282">
        <property type="entry name" value="PFDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF3">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="9">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="166"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="38410" checksum="03E34CA69A2EC84A" modified="2013-05-29" version="1">MSMKAIVYKSPFSVAVEFMPKPKIEHTNDAIIRGRTPADPGLRFGHENMGIVEEVGKGVAILKKGDRIVLPFNVSCGHCKNCERSLTAFCLTVNPGFAGGAYGFASMGPYAGGQAQYLRVPCADFNALVLPPGKAWEEDFILLADVFSTGWHGITLSSVAVWGAGPVGLMAAYSAILRGASSVFVVDRVPERLQRAQKIGCLPVDFTHSDPVEQITKRNGGMVDRGVDAVGYQAVASNGKEQPNAVLSALLQVVRPTGGIGIPGLYLPADPGAKDEETKNGNLTVPFGKLFEKGLSLGTGQANVKAYNRELRDLIVAGRAKPSFIVTRRIGIDDVPEAYEKFDKRADAKVLIHPNGWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT91</accession>
    <name>M5FT91_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_110510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625497.1">
        <property type="nucleotide sequence ID" value="XM_040769066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT91"/>
    <dbReference type="STRING" id="1858805.M5FT91"/>
    <dbReference type="GeneID" id="63684128"/>
    <dbReference type="HOGENOM" id="CLU_033465_0_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF13">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42891" checksum="D30A579AE6FB532A" modified="2013-05-29" version="1">MASNSTLPAGFVEGSWWYYAPNKVAPIVFAVLFCITGCWHLWQNWHFKSWKSSGLFPIAGFVFVIGYSMREVAAFYYTEIGFYMASNIILLCSPPVFETANLFILGRLLYYVPYHAPLHPWRFMLTFAVFQSFTESINGNGAAKATTPYSGPGEQRIGHILMQTSLMMQIFSALCFILIALRFEYNCRRAGIWPDKLRNSLRMVYLSCALIHVRTIYRTIEWFEPGDHNPNDPSSFPPVLRTEAFFWVFEASVMLTNSFLLNIFHPTRLLPTNYKVYLAPDGVTEIEGRGLGKDPRVWWMQLIDPFDVYGLFTNRDQKHNIWAQEEPNNAITKGNLTTTTSRTDSSSDSASEKKIDVGSWGNWRVQNELIRQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTC2</accession>
    <name>M5FTC2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_110535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625527.1">
        <property type="nucleotide sequence ID" value="XM_040769072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTC2"/>
    <dbReference type="STRING" id="1858805.M5FTC2"/>
    <dbReference type="GeneID" id="63684134"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="OMA" id="FSLMHTG"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="29052" checksum="BE27C4A55AA61C88" modified="2013-05-29" version="1">MKALQIPRKDIFLCTKFGLLPAPGGVRGDPEYVKSAIERSLKDLEVDYVDLYYQHRVDPKVPIEDTVRAMQELKDAGKIKHIGLSECSAETLRRAAKVAKIDAVQWEYSLWETSVEHNGILEACKELGITLVAYSPLGREMLSGKFRKRSDLPAGDWRLDAPRFSEENFPKNIELVDQLSAFASHKRCTPGQLALAWVLAQWDGIIPIPGTTRAEALEENIGSARVSLTQEELGEIRKVLDSFTVVGTRYNAQGMSLPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTC6</accession>
    <name>M5FTC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UNC-50-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_55886</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-50 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626196.1">
        <property type="nucleotide sequence ID" value="XM_040775349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTC6"/>
    <dbReference type="STRING" id="1858805.M5FTC6"/>
    <dbReference type="GeneID" id="63690411"/>
    <dbReference type="HOGENOM" id="CLU_066239_1_2_1"/>
    <dbReference type="OMA" id="YRNFMYR"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007881">
        <property type="entry name" value="UNC-50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841:SF6">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05216">
        <property type="entry name" value="UNC-50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="27980" checksum="3608093B817A2D96" modified="2013-05-29" version="1">MPILPVLSSGSRVLTGGSDAGAGWTRLPPMFRRMLRFQHMDFELALWQLTYLCIAPRKVYKQVYYHKQTHNTWARNDPAMLILISASLACGCITWSVVYSLGPVGGIRLALVMVFRDFILTGLIVCSLLWRTAPGTVQTDPGNVEWAYAFDVHCNGFVPLFFLLYVIQLILVPVITQDKWICLLLGNLLYLIAFTQYFYITYLGYNALPFLIRTEVILLPLIPILTGFVASLLGYNIARKALTLYFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTF3</accession>
    <name>M5FTF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_110564</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625557.1">
        <property type="nucleotide sequence ID" value="XM_040769080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTF3"/>
    <dbReference type="STRING" id="1858805.M5FTF3"/>
    <dbReference type="GeneID" id="63684142"/>
    <dbReference type="HOGENOM" id="CLU_001570_25_0_1"/>
    <dbReference type="OMA" id="PRITHAW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="401" mass="45063" checksum="0D37843375782D9E" modified="2013-05-29" version="1">MGNKAPWDKFQETVDALAPLGPNVFATKQNEWPRHRKVVSPAFNGLLYQAVTTETIATYYDCLATQKWEKEREFIMSDVPAITSKFALYLVAKCGFGIHLTWNEEVGERVDGKSLPECFDVTSRSVVFLSLLPRWMIRSPIPAMRRLYEASNILEKIVQDIIDKRRAEGLGDEKQAKDIFSMLLSANDLEKGSAGALSDRELVSNVFFLLLAGHETTGKALAATLGELACNPHHQQRAYEEVMSVLPDGRDPSYTDIDRLPFVQACFMEGLRMFPSVPNTMRGPIEDTVLQNKQGGITPFRVPKGTPVTLDFFGLSYNERVYPEPDTYKPERWLDPKTEPLSTFSYGPRVCIGKRFAMVESTCLLALLLLACIMGENVESVVGFGHKRFALSFTRRNATTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTI6</accession>
    <name>M5FTI6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625587.1">
        <property type="nucleotide sequence ID" value="XM_040773622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTI6"/>
    <dbReference type="STRING" id="1858805.M5FTI6"/>
    <dbReference type="GeneID" id="63688684"/>
    <dbReference type="HOGENOM" id="CLU_634628_0_0_1"/>
    <dbReference type="OMA" id="FLRRRIC"/>
    <dbReference type="OrthoDB" id="3353710at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="432" mass="48244" checksum="16F3D3DCB5BADE18" modified="2013-05-29" version="1">MLDICSSPRLRRSVLRSSLVDITNTLSSPRPPVLPSRPTLPSLPLKFLRRRICAISKLPPELLLHVCALGTLEHFSFPILFSHVCHLWRTLALSTPQLWTTIVLSKSYDDLLPPSYIHSILERGRAGPLDLRLDVGVYRKGAVADEAGAVWRAGIILDTVEPCATRWRSLELSLPSAFDLEDFLLRTLPRAQSLEKLVLHRADHNRLRSPNPQQPLQALYLPRLRYFQIDGFPLPGGVQRSTLIALRELHVLSIPVDFQPTATEWLDLLRGMTQLRLLALVGAIRRTASCDLAPTEVVPLPLLSKLDISHTPITPALYFLSHLQAPALQSLVAGSPPAGAYESLQPLCSLLTPWLYPRLRRLRLGYGRLTQSEMRVLEERDGLRVFGPVGLAGVGGLERAGGERERERRREGVEGANRRWREGLEGGWEGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTK4</accession>
    <name>M5FTK4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626321.1">
        <property type="nucleotide sequence ID" value="XM_040769010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTK4"/>
    <dbReference type="GeneID" id="63684072"/>
    <dbReference type="HOGENOM" id="CLU_2497859_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="9753" checksum="48BC94B2896B64D8" modified="2013-05-29" version="1">MVFATAAKGFHNAPTHAEDSKMLSRVKESQDDDINDNSVMHALLGAMGMDKNLIPPYPPSTGTVNELLVAPHKTPVSLEPTLISGHQDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTM0</accession>
    <name>M5FTM0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_23963</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626341.1">
        <property type="nucleotide sequence ID" value="XM_040773488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTM0"/>
    <dbReference type="STRING" id="1858805.M5FTM0"/>
    <dbReference type="GeneID" id="63688550"/>
    <dbReference type="HOGENOM" id="CLU_063749_0_1_1"/>
    <dbReference type="OMA" id="VRGNMDY"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="215" mass="23085" checksum="A4750641BD3E6BA3" modified="2013-05-29" version="1">MVLVLLIGDLHIPYRTHGLPTKFKKLLIPGKIQQILCTGNVCDRETLEYLRGIAGEVHVVKGEYDENPAFPLSLIAQHGPVRLGVLHGHQSVPLGDQDALSALARQMDVDVLVSGGTHQFSAKEHEGRFFVDPGSGTGAWAGHSENDAVPSFALMDIQGSVIVTFVYQLIDSEVRVDKIEYRKAAPAPTPTGGMSGMTSPKPTPPRGAESVWSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTM9</accession>
    <name>M5FTM9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_120019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623489.1">
        <property type="nucleotide sequence ID" value="XM_040770918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTM9"/>
    <dbReference type="STRING" id="1858805.M5FTM9"/>
    <dbReference type="GeneID" id="63685980"/>
    <dbReference type="HOGENOM" id="CLU_003794_1_1_1"/>
    <dbReference type="OMA" id="ANACGCV"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT96591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1077" mass="118452" checksum="39E680C45193BC3F" modified="2013-05-29" version="1">MDPTFVNGLHALLTTASASSDTTQIKAATATLAQQYYRNPQCVPALFQILLTAPDAGVRQLAGVELRKRIASNHAKLWTETAVEIRNEIKTKILEFALHEPISIVRHTAARVIAAIASCEMREKAWPTLLPWLYEASTAPAASTREVGVFILYSLTDSINEPFSAHVSEVYELFRRTIQDPESMEVRVNTIRALGMLAQFIDAEEKGQVRTFQSIFPQILAVLRDCVATDNSDGAKHGFDVIETLLILDTPLIGKALPELVEFFLTVAVNKEVDESIRVMALNALIYTIKYRKNKIQSLGLAKSILERIMPIGCEDEPDEEEEDNPCRLCFRCIDSLATTFPPSQVFPTLHTLVTQYVSSPDPSQRKCAMVSFGVAIEGCSEYIRPHILSLWPFLDAGLNDQEWRVRKAACIALGCVCEFLGDEAAERHEIFLPAILRLMGEEQTRSTACQALDSYLECLGDHILPYLDELMVRLIGLLETADRQMQSTIIGAIGSAAHAAKARFTPYFPEFMKRIEPCFFLTKEEDLDLRSIAVDTAGTLAEAVGAEAFRPCFEPMMQQAMAGLKLESYRIHECNYLFFIVMSRVFPDLMEPYLAAIVPELMKSCKEAEYKIGSADELEAALLGNGTAEAPLEIKSDEDVDIDLEDAADADVDDILNVSSAQAVEKEIAADAMGQIFANVKLPFLPYVENCLEMLVALLEHYYEGIRKAAVQSLIEFLRTFYVLANYEWTPGQPSAPLHDNVVKIRDVIMEALTDASSSDEEKSSVAVLCSTLGELLTSYGPTVLGTYGEQVANLATSVLDRTHVCQQDTDQETLPEDMLDEDQAEYDSVLTSSAMDLVAGLAHAYAGEFKGAFPKYMTLIATYAGKGHSLADRSAAIGTFGEIIGAMGAAVTEFTEPLFQILYPALADEGVEVRSNAAYALGVLVENSQVDTSSQYVNILRTLQPFFQTPESAAGTTLNARDNACGAVARMLLKNLTAVPPEQVLPTLFAALPLKNDTQENKPVFKCILHIYQANPALLDPYWDLLLKLFQHVLVPAGETEIDDETRTALLALVSHLNQVIPDKVAAAGLAQVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU02</accession>
    <name>M5FU02_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628053.1">
        <property type="nucleotide sequence ID" value="XM_040773016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU02"/>
    <dbReference type="STRING" id="1858805.M5FU02"/>
    <dbReference type="GeneID" id="63688078"/>
    <dbReference type="HOGENOM" id="CLU_062487_0_0_1"/>
    <dbReference type="OMA" id="ITFSACY"/>
    <dbReference type="OrthoDB" id="5288586at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF2">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="31225" checksum="94F2521328333D62" modified="2013-05-29" version="1">MTVNLAKVSNPEPEMSTLPSPSPPRESALQRTWKYVLEECDPDMSTVPLSCYCLMTGYIDSITFSACYIWCAFQTGNTIQLSLAISRLFTGPYPRELGFQEPDQQALCSLLTFLFGAFLGRIGDWWGAKRRSWLIMASLIQAGFTLAACLCALYGAQSSFAGPRGSPTWTNPLGFAALGFASASMGLQAHVGTRLGSQFATSVVLTTIWVQLVGDPKLFSPHAPIKSRDHKALAIFMLFLGGLMGRALTGTIGAANTFAVGAAMRLLIAVSWWWVPKKAPKPQPIASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUP1</accession>
    <name>M5FUP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RhoGAP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_59944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623884.1">
        <property type="nucleotide sequence ID" value="XM_040775596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUP1"/>
    <dbReference type="STRING" id="1858805.M5FUP1"/>
    <dbReference type="GeneID" id="63690658"/>
    <dbReference type="HOGENOM" id="CLU_544032_0_0_1"/>
    <dbReference type="OMA" id="RTTDIHA"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="124"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="196"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT96986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="501" mass="56318" checksum="07ABF5CB864EFF9B" modified="2013-05-29" version="1">MRPFVRTITVQLDKLKRDRQVRDRLARDIRADKEKLGKKETDANRLSTQPKKPVKPGHKKGRSVTAFFRVVRPLSTVFGTDKPDLSYADKSLPELDFSAPSKPALSLSLVHATVRVLPNEVRSFTFAVETEDGGRYVLQATSPIDREQWISAITRAAQISAARRSLMEAQAPKLDLENSDWQARPPSQHPKSVYGVNLTTLLERGDSHLTDRGMPLIISQLIEEVERRGLTETGIYRISGSRAVIESIRNNIDKGLPFELVVDEYTDIYAICDAIKQWFRDLPESILPATLLKDFEQALKIEDYNARMFRIQDLVVGLPRANFLCLRGLAEHLYKVTDYEDQNQMHADNLATVWAPTLCRLPNVSQIPIFQVFGVLGPATGIVKQCILQYHWIFNEPDEVEPESAADTELATPTADTPAVEERRFSLTVDDEGALVVQEEPLERSSIDSQASSVRMMPDIEFTGPTPEPSVDSHGEYSAAQYEYEQSFYPVAATSTIIGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUR1</accession>
    <name>M5FUR1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626891.1">
        <property type="nucleotide sequence ID" value="XM_040773278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUR1"/>
    <dbReference type="STRING" id="1858805.M5FUR1"/>
    <dbReference type="GeneID" id="63688340"/>
    <dbReference type="HOGENOM" id="CLU_371315_0_0_1"/>
    <dbReference type="OMA" id="GGEWDMQ"/>
    <dbReference type="OrthoDB" id="2129662at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="749" mass="83124" checksum="DEF338C36650597B" modified="2013-05-29" version="1">MEPDVYSLNMDLLSFRNQSSSSLYNNSNGSSNNGLTMPPLPDSAANPSLEEQRLKLQLARETVRLRELELQLDLEQRKQRVRELDLQIAAEKRKEREAEVELARLQAMHVSPSVPESASNPALQNGDTPNSTTVNTGLQNMTPFTPMIDFNFMQMSNPALASTGMDNFPGMGMFGDSGFATWTGMPTGPTMAPFSGLDMSNGVGGPVASPTTMDPGFEDMLKEIFGGPEHAIPPEPPLSLSSGSPDDPAAIGADDADDHADDALVQGPSTTASGSSGSSASPLTQAPLAPSARRSRKLRIETLITCSNCGNPIAKLLLRGTREELDVPYELRYLCEDCTTPVTFGEQPQIKRRIKQGNDTTMPTVCDVCLRRQGTGGIVPKFPEQTLEFASEVVCLQCTEKYQRCSDCGGGSGRAGAGKWRCKELFDEGRKTCNLSHARLGTGDLEMASWDVSDTFRQDVMIDSVIEACEVLWKDNFLRLAVPEVLEVDSDSPLQLKTFQDIENKILASGWPAKDFVLKGPGPGQRHYVSLTWARNRPRRGKPVIEELPEEVNEEDKLLANLRRTTKLYPPGYMLVNIWLSQWDISSRTIRLFTTSPFENSDLDAHSSIAIAEMFRKIIAAGTDDYASANRPPLHVWMTFEKLGPMIDQRVEDAFVKKRAFLPLEAYIQRHADMDQDQFRWPAYTRAALDPQYRQSGESPVLVLVKHLGSSMSWQKLLQLKIQEMKDRKEASQLIRKRKATDEVEARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUS0</accession>
    <name>M5FUS0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_96078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626142.1">
        <property type="nucleotide sequence ID" value="XM_040777346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUS0"/>
    <dbReference type="STRING" id="1858805.M5FUS0"/>
    <dbReference type="GeneID" id="63692408"/>
    <dbReference type="HOGENOM" id="CLU_324954_0_0_1"/>
    <dbReference type="OMA" id="RMWMDVD"/>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="54"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="844"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="878" mass="97276" checksum="000CCEADD86ABEF6" modified="2013-05-29" version="1">MAPLNLQADQAALLKAYRIHTLEPQAWEDIEHDLDENGIVAGVANPIAREAEEDALGIGRGRGVDLGKLDLETRASILLTSKSFDPKSYLMHVYPSASYSDLASAIPRLQASIDSRSEAIRILVEENFDRFVAVKSSTSSIGESITSSFSQETDYKTKDLTAALKQASSKANQVFIPILEASSSATKLRSTLAVFSRSKYLFNLPSVLNEAIDAGKYDLAIRSYKKGRAVRERPPPNIGITESRILDKVWTSVERIIADLRDNLLSRLREPGVPVDEVEKTIEMLLELDGPEDPVWTYFDAQHQRMADRLRAVYERMAERVKLARERAASEVMGEEERAQVLKACVLALDERNGEAVIAKGTGWEVWESNLSLVKQLSEVLVSSLPAFWKIARGWTEGRFKRTSPTASGTRRAPAQIRTMSLELTRLYVSLVSQHFSLSDPNSSPLASSTFHFLPPATNSLTSAQYLEKLLGELNDCVGDVVGLEMGGGGEAGEGLKGLVETARWRYVDVLCDAWHNDSKLFHHLESFTFVPPTSGPTSITASPAYLDRVRQFQQHNASLCFKLASPSLGEKNKLPPAPYVNRIKTAFLDSLYSILDGLVRFASEDGEPVGSANDTESDVDNRILVTVSNLYHLDKELIPRMMSDLEKASHSKLSEDRGTLSDVVQELDKTLFDDFAKSKAAVLTGIIRRGVLGSGMDWATIGRPQEVRSYMYDALIYLVQIHSQVSLMARPLLERTLSSLVMSIAVEALACFKQVTRFGMGGMLAATLEIEFFHQTMLQYVSPEAAATLGEIYTTISQVYQKAPPAGGVGAANLQTELDAVKKTLHDGRKGTSVEFLCFKQKKEKEKEKERWKEKDKERPDKGKEGDRATPTKRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVH8</accession>
    <name>M5FVH8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_95946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626512.1">
        <property type="nucleotide sequence ID" value="XM_040777333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVH8"/>
    <dbReference type="STRING" id="1858805.M5FVH8"/>
    <dbReference type="GeneID" id="63692395"/>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="OMA" id="AHIATEF"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015137">
        <property type="term" value="F:citrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="MFS multidrug resistance transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="82"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="57949" checksum="0D66FC30F8FAE09F" modified="2013-05-29" version="1">MATTSTTPTIAQGGTSSRSRNTADEAPVDSPPVFEDNGMNINEMGSAVEILEQLDGQTIRGGDETTTADILVVFKRWEIWVIVYLTSIAALFSPLSANIYFPAIPVIAQAFNEPVELINVTVTVYMILQGTSPMVWGSLADWKGCGRRPIYLACLLLLCLSCVGLALTPTTDYWLLVFLRCVQAAGSASSVAISAGTIMDVAAPHERGTMLAMSSIGALVAPCIGPVIGGLLAGNLGWRSIFWFLCICSGVVLLLEALFLPETLRTITGDGSVPAQKWNRPFIPVLLRDVQDEGKSPDAVRGRNNPIEIIKSFRNIDLCIILWSNAVPYSVLYGILTTMSPTFLAVMPSLTEIDLGLCYLSIGAGGIAGALGSGKLVDWDFRRAKKLALQKQGMRTEDAAEKATDIKGSSKYEGIECIERTRLRLSPAYWASFVVIVIGYGWAAERKVHIACLLILQFLAMFQVTAIFTLNQTLLMDLFPGRGASVTASNNVVRCLTGAVLVSIVDYIINGVGVGWTFTILGACHAGDGLGTEMEGEESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW54</accession>
    <name>M5FW54_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626792.1">
        <property type="nucleotide sequence ID" value="XM_040770400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW54"/>
    <dbReference type="GeneID" id="63685462"/>
    <dbReference type="HOGENOM" id="CLU_1266857_0_0_1"/>
    <dbReference type="OrthoDB" id="3358294at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="218" mass="24107" checksum="DC4DF825BEEED325" modified="2013-05-29" version="1">MSIRIPFVGTFICTVAPPPEAHIPPRRTPSGNWVLSSSPAPPYYSETLDLENFGYNSMLTALTEPGRPREYADPRELAAGARELGLPNPLPMYCHEADEPNEPDTIAKKLFIFGFMFPLLWLVGACILCVPLHAYPLPPTSPDHPDNSATTSPTSESSAPEYTKDPRPANLDTVWTQPLIDLYGRAERHWAWRCVWALTSLCLLGTTIACALMGMRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWX6</accession>
    <name>M5FWX6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627821.1">
        <property type="nucleotide sequence ID" value="XM_040777284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWX6"/>
    <dbReference type="GeneID" id="63692346"/>
    <dbReference type="HOGENOM" id="CLU_2654457_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="76" mass="8290" checksum="92B85FFFDD07114C" modified="2013-05-29" version="1">MTCNADFLPRRLVPRSSRPASPTIGPRNISTWSSSDRNGIVLLREVTEPARDVGRTSSPDSPPSDPDPTSSQQRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX88</accession>
    <name>M5FX88_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="16">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_111074</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="16"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624989.1">
        <property type="nucleotide sequence ID" value="XM_040769168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX88"/>
    <dbReference type="STRING" id="1858805.M5FX88"/>
    <dbReference type="GeneID" id="63684230"/>
    <dbReference type="HOGENOM" id="CLU_014329_1_1_1"/>
    <dbReference type="OrthoDB" id="5963188at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048257">
        <property type="term" value="F:3'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000005">
        <property type="entry name" value="crossover junction endonuclease MUS81 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="18">
        <location>
            <begin position="463"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="118"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="392"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="708"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00058015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJT98091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="766" mass="85436" checksum="433328C07334D4DC" modified="2013-05-29" version="1">MSLNTRLANYLLEFRDQHDPDSNLYRTYNKAYNHMRRHGEPITSVEEAGHVFGVGKTILRMLTNRLENDGGTNASVPGPSRRAPRSSDPPDSLLNNRFYNPSMLDFLDELEVPLPACHSRGRGNGRGARGGVQARRGKGKRGRTDERGDEELVGGSPTKKRASGWSGGIPRNVRETVDDCALLEYMDPPHGVPSDSYPGLGFWYLDTDNTRVAHYEQAEIRIVAPFVLRKVELPIKSTLPPPVPPPFKLVYLEGQPLWTKPPSRVAWVEEELLLEKSWDTCPGFAEVLPTAPSLDPWAPTSTSSQVRNPVPDPGADAEDLASLLAQERRSNICTLDPSRTGRSRMGMAPQPMPPPSSIDGVEYMAEPLDARRAAAEAAEKWHQAAEIAKKAATHSCSSQTAKDKIPPRTTSAPITARPVPAATNLPPRAASASFFPQRRLSVAEIQFPVFRPIVIPANTYDILLLLDNREIGRYGNHDAIKDGLEKLGVQVEQRVLAVGDVVWLARSKMDGKECVLNWIVERKRLDDLCMSIKDSRFQDQKFRLSQSGLLHVFYLVEHFAAERLMRDHELLINTALSRTQVVDEFRVSETRSQQETVEFLANMHSAIRILMDGRALHVLPSSVISRATYVAFQAHLRKREPTIQYLPTWSDFQSLNTKNATRTVQETWARMLLCVKGLSAERTSKLLDHYGTPREIWEAYCRFTESGASHSGASGTSSDPVSKMRGKKHLSGPKTMLAELGGEGRRKIGNALSEKIWEVMMSKTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXR1</accession>
    <name>M5FXR1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_115785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629715.1">
        <property type="nucleotide sequence ID" value="XM_040770079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXR1"/>
    <dbReference type="STRING" id="1858805.M5FXR1"/>
    <dbReference type="GeneID" id="63685141"/>
    <dbReference type="HOGENOM" id="CLU_026174_0_0_1"/>
    <dbReference type="OMA" id="NYHGNYG"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12524">
        <property type="entry name" value="RRM1_MEI2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034453">
        <property type="entry name" value="MEI2-like_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="140"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="569" mass="63120" checksum="E8E02719E0DC1C50" modified="2013-05-29" version="1">MLRGPYSGYDEHAVPMRRPSPPPRYGGPDNRGGYGGNERGYNDHGGNDRRGRGGRGRNRGRGGRGGGGGPPQSAYPQYDDAAMDPYYPPAPPQDDYYRDEYGTGDYDDPSRRRAPPPPRREREVNENLIEERIQRERPCRTLFIRNIKYESNGEAIRARFEEFGEIRTFFDLISNRGMVFVTFYDLRAAERARDRLQGTDIAGRPIDVHYSLPRENETNSRCDREKNQGSVQVTLRDSSNRQPINQGEVRRIFTQHGDVKSVRAVGSARDAVVVELYDMRATEQIIDTMNHAPLQDGYMELDWAWDIPDTPLPAPPTPTQPLPRRPEPSREREPRGYEDDYRDSAPRGGGGGRGRGRGRGRGGGGYDDRDDRRSRRDSRGHDDFEPRRNSGRQEDRYPEDPYRAPRAAGAIGQPESDRLEAAKKVQELLQALKPPTTAQTQSPTRAAQPPPPPQQPAYYGAPPLNPYMPPQPQSAVPSYPVPAAPGPQLIPNAATIAASLPPSVLALLHQANAFGQPGQPVYQPPAAAAPNPYGAPSYSQPPASANLPTTNPTAMQQILEMIAAQSKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXX7</accession>
    <name>M5FXX7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628271.1">
        <property type="nucleotide sequence ID" value="XM_040772846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXX7"/>
    <dbReference type="STRING" id="1858805.M5FXX7"/>
    <dbReference type="GeneID" id="63687908"/>
    <dbReference type="HOGENOM" id="CLU_030612_1_1_1"/>
    <dbReference type="OMA" id="GSMSMCA"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="47942" checksum="5D19B5E3B0249E68" modified="2013-05-29" version="1">MSGHGPSAEDVQEEQAHFRQVVTTFRQYRQYSLSANIRRRKDFYSLPLPHQKLLREVGWYQKLGDVDDAILVNADFLEQIVDDTEIFAGSVDDLEEASTGGEQEEASSSDAHPHAEHTHEHGAHGHSHGRHSHGHAHTHERVVGSSSVPAHEHRQKVSEPDMDKLRSTLKQFVRDWSAEGKKERDEQYEPILQALEEHFKDIPEDGRSDIQVLVPGAGLGRLTWEVVNRGFSCQGNEFSYFMLLSSFFMLNRSPETNKWTIYPHIHSLSNLQSEASLLQPIMIPDVLPGERKQGPDFSQVAGDFEEVYGLGARDQAEAWDAVLTCFFIDTAKNIVSYLEIIRHLLTPGGVWINLGPLLWHFENNSTKDVSIELNLAEVKVLAEKMGFKIENERMIETTYVGHEDAMLHHVYNCAFWTATKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY28</accession>
    <name>M5FY28_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Di-copper centre-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_106148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629865.1">
        <property type="nucleotide sequence ID" value="XM_040768209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY28"/>
    <dbReference type="STRING" id="1858805.M5FY28"/>
    <dbReference type="GeneID" id="63683271"/>
    <dbReference type="HOGENOM" id="CLU_532111_0_0_1"/>
    <dbReference type="OMA" id="ANIDRHW"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067436" evidence="3">
        <location>
            <begin position="23"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="512" mass="54990" checksum="FD64E8208AF636D4" modified="2013-05-29" version="1">MRARRTLSLILCCIFSLSPSHASPTSSISNSTNSTINALSGPALAVDTDQLAVFTTRNQQAGWPVILGTVLRGGPTNATISWSFPQLGSVLCTVSGVVNQSCAGPVLDVIFPSAGSYGVSITITDASTNALFTTQTFSVNISTGNAVPTGTRREVRDLTTGQWSRFVQAAHVLKTFGVWDHIARLHSAAMQDKSMERSASHGGPSFLPWHRAFIRVTELCLQTAGNDMSITLPYWDWTFDQPSFASSPILTDSFFGGNGDPSVNGAVTSGHFCDASVSSCPSSSNWPVPVEFGGPTLRRTFAADLGATISTQAQMDALTAVELYDQSPFDANSTAGFRAGMEGWILGVYGEMHNGIHRWLGGQFSNVPTSFFDPVFVAHHANIDRHWYAWQQAKGCVDWNDGCYAPIDDDPLVNSSTPGAAQLNGTWRIPGHQWSDHMWPWGIAPKDVATASIYSTWYTYADRGTLSTDAPMPIVAGEGAIEFVSAAPNGFLEHFVVLLYVAVVVSIAVSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY60</accession>
    <name>M5FY60_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_57592</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PAAF1/RPN14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625394.1">
        <property type="nucleotide sequence ID" value="XM_040775454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY60"/>
    <dbReference type="STRING" id="1858805.M5FY60"/>
    <dbReference type="GeneID" id="63690516"/>
    <dbReference type="HOGENOM" id="CLU_037051_3_0_1"/>
    <dbReference type="OMA" id="TYTAACH"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF19">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT RPN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="194"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="419" mass="44253" checksum="7F66A84BF794A0C4" modified="2013-05-29" version="1">MASNEHTVLPQITIQPTYPSVLADVNSSLVTAEDIWISCYLEGRNSVHGKVRISRERDAPGGVKLEARNGVQVEWVNSSVLRVSCPSLDIPPTLVRFPRQSIPVSPGTQITTLSPSPDLSLLATGSASGSITLIPLSTPDTPNPSAGPQTFTPHLSTVLSVRILPSSQVILSSGSDCQLHISPVVPPLTPARVLSGHKRGVTDTYIVDRGRQVVSCAKDGTVRVWDVAAGKSARMLAGIVPPAEMDLSYLQPDAPAVNGTAPSTNGSIPEQGHLPLLAVALSSGLFTLLDLRVPSSQTIYTSPKTSTSSSNALQSIALSPTQIYTGSLKGQLNAYDLRHLPSPLWSTKRNGSSIEDLVLSSQGLAVASEDGLPYLIREGHGGPEVAEEWAGWECDAVRCLRAEGGSVWAGGNDGVVRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYB7</accession>
    <name>M5FYB7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627722.1">
        <property type="nucleotide sequence ID" value="XM_040773120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYB7"/>
    <dbReference type="GeneID" id="63688182"/>
    <dbReference type="HOGENOM" id="CLU_1408719_0_0_1"/>
    <dbReference type="OrthoDB" id="10421544at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067441" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="19809" checksum="030F81DE607E299D" modified="2013-05-29" version="1">MQFTRFTTTLLFVFAFFGLVAIAAPVPAINELEERCAFGCNDGAVVSILANLHVTVKADIAVVANLVAQASVDATLYTAVFATLIADINAAITLIAALPVSVVGLSAGLIASTCANIFIDIFVVINSCSSIPNIASCYGGLNEVLVALLGSLKVCLGNVIVSLIATLCVTIKAVISLSVNVDIFAGLSAVLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYI1</accession>
    <name>M5FYI1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627822.1">
        <property type="nucleotide sequence ID" value="XM_040772951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYI1"/>
    <dbReference type="GeneID" id="63688013"/>
    <dbReference type="HOGENOM" id="CLU_2867607_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="64" mass="6804" checksum="372552415817F7D8" modified="2013-05-29" version="1">MQVWVQSYTLSGGLGRWISWVEVKGDAEPTGASDGLEAICSSRHGGGNDDHLERVQGGSEDESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ75</accession>
    <name>M5FZ75_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630240.1">
        <property type="nucleotide sequence ID" value="XM_040772437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ75"/>
    <dbReference type="GeneID" id="63687499"/>
    <dbReference type="HOGENOM" id="CLU_2573828_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="81" mass="8564" checksum="164214B2AC51AC36" modified="2013-05-29" version="1">MSNPAQTAPAQSKPTSAPPPAAKPAAPKPAKPIPIPNGTALLNGGTGISKPRRTARSEDGRFGRSEEEERRGRSRDVRPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZI7</accession>
    <name>M5FZI7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628192.1">
        <property type="nucleotide sequence ID" value="XM_040772822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZI7"/>
    <dbReference type="STRING" id="1858805.M5FZI7"/>
    <dbReference type="GeneID" id="63687884"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="35155" checksum="A59A49F767244845" modified="2013-05-29" version="1">MGNYLSAIDDEWQQAWPPKPTWSVDDIPDLGGKVAIVTGGNSGLGRLTAKYLALHNCTVYLGCHTLSKGEEAVAELQVESGNNSIHCLELDLSDLESVALAVKEFRKREERLDILFCNAGVMGPPLEMLTKQGLDLTFGIGFVGHAYLTMLLLPVLLSTAKTTPGNKVRVINVSSSAQAWAPAGGVDFGLVMDTDERKARGTSMLMLTQTRWALACFTQELNRRYASQGITAVAVNPGNTRASASRYTPTLTRWALDHVLGFAPDPLGVLTSLYAGTAEETSDMGGAFFWPWARVGHARDDTKDEKMGSLLWEFVEEQGKKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZJ1</accession>
    <name>M5FZJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630345.1">
        <property type="nucleotide sequence ID" value="XM_040768117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZJ1"/>
    <dbReference type="STRING" id="1858805.M5FZJ1"/>
    <dbReference type="GeneID" id="63683179"/>
    <dbReference type="HOGENOM" id="CLU_012740_0_0_1"/>
    <dbReference type="OMA" id="REGMPYK"/>
    <dbReference type="OrthoDB" id="5964929at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="621"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="891" mass="95951" checksum="F077BF9DEF9596D6" modified="2013-05-29" version="1">MDWLDNLKRAEIVRLCKQHGVKVQGKNTDLVAKLRPLVVGPQEMQEVQDQDQEWEVLDGDSPSLPRARTIEVLPTLFTGTQTTTLIPKSSSLGTGILKLAMGIKRGSGRSTHAELADFKPSLPNDSLETLLLPRAPDAQSINTNTNIDGSMMQVDELGPLPAPQFANTDSPAQTIRLVSSQRAQDSPAREDQSHQLLSSMFPVLPETLREEVDDVPRMYPPLDPELPGAFPAHADQHSVFPSPRRLHKPTDPLPSPYKPGQGYTPPPAPAQEASTPFQYIFGSPQRGVSKAEFTKVTRNVLDELNKRVVAAGGKAVPTKSFGGDWESIAAVESAGQEEQSKKTRFEKSHQKGFNLMDSIATHYAARRPESRVGVREEQPQAQKKRKSTHPISAPSRAPTGSTTAGAAKRSEDGEEDEGAQRAKRRKMQEGTSEAPTAVPGGKAEVWVRVRDTPAQRRKLDSALRRRSLTRRPSLPRLPVDLLSTTGGGTGTTAGTGTATTAAPGKPTFLGRTANAFKGVFSTGPVSTVAGTTVKAGMKVMPVPPAPRMLNLLEVPVSATSGSGGSAQGGDKHGHPSKQEKKHEPKNVLPPTALPVPVPNVTKKGYAGLSAAQGRPLAVAGRTPSASRADTRRTASNSSTNSTGATKQRIPSGPVRKVPPTFHDKGDKENMPFFPATQVAKNDAFRAHAAMKEIQMNKGEREPPLTAKKSTLHAPTISSLARMQATLRPEEPFSPFRPPTEAQAFPTPKTGVPRTPLTIRSKRGLPTASVPRPGSLRFSSPLKPFFHHLSPAKPSPSKTGLKRKPRISRAHVISKLNERRNAAAAVGTPSPRKHSLATRTSSRRSLGLKAAAGLARPNMELQRRAKQSEIARRKSIRALNSPVKRQEIGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX6</accession>
    <name>M5FZX6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628347.1">
        <property type="nucleotide sequence ID" value="XM_040772867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX6"/>
    <dbReference type="GeneID" id="63687929"/>
    <dbReference type="HOGENOM" id="CLU_2454699_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="89" mass="10628" checksum="1F0F1E6D9F4B1BBF" modified="2013-05-29" version="1">MTTASLDSLTEDQIRFREWFNNTEVPRLQYLRVYTNDPYKKGWGNAIVHAYRDLMPRMGKEHEHEWYGIINMVLVKLFDSSEYLISNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G095</accession>
    <name>M5G095_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624095.1">
        <property type="nucleotide sequence ID" value="XM_040771405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G095"/>
    <dbReference type="STRING" id="1858805.M5G095"/>
    <dbReference type="GeneID" id="63686467"/>
    <dbReference type="HOGENOM" id="CLU_983603_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="283" mass="31128" checksum="9396DF0A83BBFA01" modified="2013-05-29" version="1">MMDPTQEDIYAPLPSLPPWPMLLSATSLPSSQPSSFPQYAALSFSSYPSSSLFNISNHVLGLHLEDSPACVPPQAVQAAPSTKHKTQPSSKDPPSQKHISKGQPQGSRGYTNIELSRLIDLLAHAPKPMGKGKMIKMGNLQDEDGGDDSDVLNWPTSDHEEHLKAVQPMYLTPVTNTLSPASKVQAEHAIFQSEITALQAQLHDKQQELVDVSCDKDKIIEGLHVRLLEDVHAHLGVQQELDMMKAQLEYQEQMRTMMMGMGNMGTWIVQSMNAPPHAEALQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0D8</accession>
    <name>M5G0D8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626194.1">
        <property type="nucleotide sequence ID" value="XM_040773439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0D8"/>
    <dbReference type="STRING" id="1858805.M5G0D8"/>
    <dbReference type="GeneID" id="63688501"/>
    <dbReference type="HOGENOM" id="CLU_029722_0_0_1"/>
    <dbReference type="OMA" id="WNYLDAP"/>
    <dbReference type="OrthoDB" id="48057at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF212">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56328" checksum="97C1F946D3EF3FBA" modified="2013-05-29" version="1">MSAAADIANGSVHLPAEPKLDGAAFDDATVDTPISVGESSDASETSKLRMILQLVKKCFGVSDIANMRLSLPSVLLAPVPNLEYWSYTDRPDILASVNDSPDPFDRMLSVLRFVFSKDLKFIRGGVCKPYNSVLGEHFRCHYRVPALPNPPEPQFVPKSYLHIPTPAARSEGSSLRSFGSWKSGQREKPASISQLSSQLENVVIMEDGLELNGEEAQIVFITEQVSHHPPMSSYYYEVVDRGIQLSGVDQIAARLSGASVRIAPGDKNKGLFIKLTSGPGEGEEYHVTHPIAAVNGLLTMRLYASITDSVIVTCRGGKDGKLLRAIIEYKDEGWIGKPQRAVEGVIHTYDPDSVEQEEWRKVKHVPLDRHLARFEGAWDKKINWRRASESDWRPLIDLSTLSLVPKIVRPLPEQLHNESRRFWKDVTENLNKKNYNEATACKLRIEQSQRDIAAERKRKGVHFTPVYFDKDIEDGRSRLNDDGRKAIMEEIERARTGSRSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G178</accession>
    <name>M5G178_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_40654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626479.1">
        <property type="nucleotide sequence ID" value="XM_040774488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G178"/>
    <dbReference type="STRING" id="1858805.M5G178"/>
    <dbReference type="GeneID" id="63689550"/>
    <dbReference type="HOGENOM" id="CLU_2549109_0_0_1"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9660" checksum="BEBC83754076D4FF" modified="2013-05-29" version="1" fragment="single">AQSAHYFKYPDAWREIGRVLRPGGTVAFWSYPTLMLPEGKRFSDLNEKLLRFLLGTGPNRIGQYWNPTAREILWSHFTKLPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1M0</accession>
    <name>M5G1M0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_111683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624540.1">
        <property type="nucleotide sequence ID" value="XM_040769277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1M0"/>
    <dbReference type="STRING" id="1858805.M5G1M0"/>
    <dbReference type="GeneID" id="63684339"/>
    <dbReference type="HOGENOM" id="CLU_071335_0_0_1"/>
    <dbReference type="OrthoDB" id="3058140at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067405" evidence="2">
        <location>
            <begin position="19"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="231" mass="25426" checksum="05EA2C6F8F030EAA" modified="2013-05-29" version="1">MRFYYLLYLVTLVHPILALPTPHRLYKRSRTWDDITEHYLADRDFDLAGLPNGEVLLRRDFEARYTVEKDINTRTSEEEDDNRLRKRSKIGDAFKAFGRKLKKGFQKAGSAIKKGFQKVGEGIKKAAVKVGQGIKKAAVKVAQGVKKAWNSTAGKIVRKVVEVVGNVVSTFIPPLKIVTTAATIAKVAVGAAKAGKAIKAAKTAATTAKHAVKAANNNNNNNNNNQNKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1M9</accession>
    <name>M5G1M9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-3-methyladenine glycosylase II</fullName>
            <ecNumber evidence="4">3.2.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-methyladenine DNA glycosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_23769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.</text>
            <dbReference type="EC" id="3.2.2.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="4"/>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626659.1">
        <property type="nucleotide sequence ID" value="XM_040773382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1M9"/>
    <dbReference type="STRING" id="1858805.M5G1M9"/>
    <dbReference type="GeneID" id="63688444"/>
    <dbReference type="HOGENOM" id="CLU_2489336_0_0_1"/>
    <dbReference type="OrthoDB" id="5568149at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="entry name" value="Methylpurine-DNA glycosylase (MPG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429:SF0">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="87" mass="9707" checksum="4FB4F013216ACDA8" modified="2013-05-29" version="1" fragment="single">MEPLLVQPAPLPARALLNCILHRHLPSGAHLSARIVETEYYHQSDPAAHCYPGTRTPRNSVMFGPPGRAYVYRSYGIHWCLNCVVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G241</accession>
    <name>M5G241_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_119054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624730.1">
        <property type="nucleotide sequence ID" value="XM_040770715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G241"/>
    <dbReference type="GeneID" id="63685777"/>
    <dbReference type="HOGENOM" id="CLU_735700_0_0_1"/>
    <dbReference type="OrthoDB" id="3351939at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="43354" checksum="8D914ED90736E6DE" modified="2013-05-29" version="1" fragment="single">MNGLPPELLQHVFEAVVNDWEEDPGRIWSTLMDFHAYIFLVNRTWNTTARHTSTIWRNIPLHRGFFDYAEFCLLHSGNQPLNVQASMSESFRELMTPERANRVQRLEVEDKEAYRHWMTVLLSLPISKLEYLSMNSLCSSWEESLAFLVGNKNLHELEITRFFHQPLSPASSGVHPVLPKLKKLKISDWAQETQSVLSSFSAPSLETLHIAVNDEHRYGQRFRPMTLGTMDIFSSVKEVIFQFAITTEDVLAVLRQTPNVEVLRLAHSWRFEASFDDLLAQLCNPSIPILLAPRLQVLSLHEFPVWMPAILGLVRARLSRSRTCLSTVEGIGQRVLPLRRVDLSPRTTMFYPKADVERLREICEVRVWTPPPGDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2U2</accession>
    <name>M5G2U2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_47658</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631440.1">
        <property type="nucleotide sequence ID" value="XM_040774773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2U2"/>
    <dbReference type="STRING" id="1858805.M5G2U2"/>
    <dbReference type="GeneID" id="63689835"/>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OMA" id="TAPKTCE"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000022">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="185" mass="20264" checksum="4FD759F4BA2BE832" modified="2013-05-29" version="1">MVKPRVFMNFNIADAPAGRVIFELFNDTAPKTAENFRALCTGEKGVSPISEVPLYYKGCTIHRAIKNFMIQGGDFTKGNGTGGESIYGAPFPDEDFHRPIDSEGLLVMANRGPDTNSSQFFVTVRPCPHLNGKHVCFGRVVTGYDVIEKIVNVETDSKDRPLEKVVVASCGELEFRRAPVKPAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2W2</accession>
    <name>M5G2W2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="14">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_88363</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="14">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="14"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629459.1">
        <property type="nucleotide sequence ID" value="XM_040776846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2W2"/>
    <dbReference type="STRING" id="1858805.M5G2W2"/>
    <dbReference type="GeneID" id="63691908"/>
    <dbReference type="HOGENOM" id="CLU_027359_3_0_1"/>
    <dbReference type="OMA" id="IGYHRLY"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14 15" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="17">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU02565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="458" mass="51768" checksum="6B8B48BB40EAA5A3" modified="2013-05-29" version="1">MVESKSNEIASMIRISPSSSTHPAEMAKKYPIWWSNASFFVGMHIVGVIGAVWLSPWGSLKRQTLYLCIWSWQLASFGVTIGYHRLWSHKGFTARLPLRIVLAVMGSLGFQGSIKWWVLRHRLHHRFTDDPVHDPYAASLGLLFSHMGWIFWKPKYERLVLIEKGDLERDPVVRFQHRHYIPIALFFGLVCPTVIALAWGDMLGGFIWGGVIARLLIWHCTFMINSLAHWEGLQPYTRDISARGSFIIAVMTSGEGNHNFHAFPQDFRNGPHPLDWDPTKWLIWLFHKFTPFAPRIRVTPEPDILKARAHVLDAEADLDGVDSIKKAALQKKAAELRALVPPYEWGIPEHKLEAWGRKQLETYVENRGRKVVLVDGWFVDVTSYIKDHPGGSSILSRYLAVSPVKETVHDSGVDMEESDDGVTEALKDATAAFNGGLNNHSSAAKAKLKALRVARMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Z3</accession>
    <name>M5G2Z3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627094.1">
        <property type="nucleotide sequence ID" value="XM_040768770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Z3"/>
    <dbReference type="STRING" id="1858805.M5G2Z3"/>
    <dbReference type="GeneID" id="63683832"/>
    <dbReference type="HOGENOM" id="CLU_667346_0_0_1"/>
    <dbReference type="OMA" id="MAPIACK"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="113"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="412" mass="46187" checksum="1FD9773F00060D3E" modified="2013-05-29" version="1">MAGPRVQRWRLLYLFLFILCFPITIPLSVSLIVPLLAADALARRLSLATYSRPPPLTQFRERLKSGLYALRWLLQAVDFVPTMLYALKLVIWDVFDLRSGMRERRHISNVPVDIYLATPTASDKEKSCPIVVFIHDGNYGPIVCRKWMMAPIACKLQRIGCTVIMPEVDPTKKEDMEVIIRNLKLVLAWTNTHAAEIHGDADEIYVMGHGFGAYLALLLSVQMAAVRSRNDYQLHNPDYQTSQDHDDGLAAHHHEVVLPNGLMEARIYAPDVSSVTIKGLILIAPISDTQKHLEWEATQGVSYLSPMRQILGRSCLFHSPAHLLFAARSILNVQYLPSKLLVLHGAQDMVVRSSQSDMLEELLMGAGLQTVQKRLYPKLDHMALLKGIEDDGVANKSSVVLDDVIGFMTSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3C7</accession>
    <name>M5G3C7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_106357</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630078.1">
        <property type="nucleotide sequence ID" value="XM_040768254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3C7"/>
    <dbReference type="STRING" id="1858805.M5G3C7"/>
    <dbReference type="GeneID" id="63683316"/>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OMA" id="FTWVCFM"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="43"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="510" mass="57832" checksum="F206E2C84E101199" modified="2013-05-29" version="1">MSSADSDILAEKPTKRSLKSYIWDTWDKSPEERKFLGRLDACLLTYAALSYFSKYLDQQNVTNAYVSGMQTDLGLGGNQLNYITTAWTCGYVIGQIPSNMLITRLQPSIWIPAMELIWSVLTMLLATSKNFTHLVVIRFFVGVAESTFYPGMQYVIGSWYKPDELGKRACVFHTTSAIGPMFSGFLQAGAYAGLNNRYGIAGWKWLFIIDGIITVPIAILGFLIMPNLPHNTKPSRLYTEEQLDMARRRMAEIGRKAPTKYTWEKVKGFFKTWHWYTLVPLYVLFNNGSNPQSSMIFWLQSFNTPGHTVFTVAQINVYPLGMNAIQVVTTLIWAWWSDAVQARWPPMVFAGLWSAVTCTVLATTSLYGNVPLRWTFYYFTLVSGGLSGLILAWANELCGNDSEKRSFVVACCNTFAYVFQAWLPIVLFPQVEQPRVEKGTIATIFINLGMIGFALLTYALQTRDRRRARRRRMQEDAADRTVEVDVLDEEELDTKAKDAEQAIIIQELPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3T6</accession>
    <name>M5G3T6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatases II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_66098</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629769.1">
        <property type="nucleotide sequence ID" value="XM_040775804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3T6"/>
    <dbReference type="STRING" id="1858805.M5G3T6"/>
    <dbReference type="GeneID" id="63690866"/>
    <dbReference type="HOGENOM" id="CLU_001645_9_13_1"/>
    <dbReference type="OMA" id="GHKWWIA"/>
    <dbReference type="OrthoDB" id="10253954at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00047">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="37"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="206"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="35185" checksum="E4AEC92C58A37911" modified="2013-05-29" version="1" fragment="single">MRRRLKDFPPTSAEGTPKDPQEYYSIRLGMYAQAQGKNRYTGGIVPYDHNLVLPPPSITGGSEYVNASWVRELHGGKWWIAAQAPVPSTVHPFLSLCCAPVASPSLGAGQPKRRRVQAIVVLTRDVELRIRKADPYIPPSVGESVVHPPPESNPQGQPIKVTLLSRENLPGQVVLSKLEVNGLPVEHWCYEGWPDHGVPLTGGPLLGMIEEVDDSLSSEGTAQDGEELEGKLAIVHCSAGIGRTGTWIALCSLLRTYSLLRPVPAPTPNGPFGPSPLGTFPPLVVPPSEPAQDLVAWEVDSLRDQRTGMVQRDEQVLWVYQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Y2</accession>
    <name>M5G3Y2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630278.1">
        <property type="nucleotide sequence ID" value="XM_040768284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Y2"/>
    <dbReference type="GeneID" id="63683346"/>
    <dbReference type="HOGENOM" id="CLU_2722177_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="72" mass="7993" checksum="E2A02150664362D6" modified="2013-05-29" version="1">MSTTPAKKMLKLIPKPPTGAQLLSGAIKIMDRMNAALDKPIFSAANGEWHRVANLPKVWLDVLPEDDREELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G465</accession>
    <name>M5G465_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_21368</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629899.1">
        <property type="nucleotide sequence ID" value="XM_040772363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G465"/>
    <dbReference type="GeneID" id="63687425"/>
    <dbReference type="HOGENOM" id="CLU_090067_0_0_1"/>
    <dbReference type="OMA" id="PGHEHFA"/>
    <dbReference type="OrthoDB" id="432881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="33"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="204" mass="22587" checksum="2F1F4916739F421C" modified="2013-05-29" version="1">MIYAGLFIFILSAWYLTFLSHGGNTEREWFIYHPTLQSIGIALLAIGIQTLQPTATPSSKASGLMRHQYFQLTCLSLLTLGTASIVLNKFAHSAPHLISWHAVFGLIAYLWLIVQSSIGAATVWFNGRAFGGETKAKRVWKYHRLSGYMLTLWMLTTAWLAGEWSGWARMYAGVGVRAVGFGMSLALVVVGLGGRVRTGKMKVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4M6</accession>
    <name>M5G4M6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkyl transferase</fullName>
            <ecNumber evidence="4">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_117208</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627709.1">
        <property type="nucleotide sequence ID" value="XM_040770338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4M6"/>
    <dbReference type="STRING" id="1858805.M5G4M6"/>
    <dbReference type="GeneID" id="63685400"/>
    <dbReference type="HOGENOM" id="CLU_038505_0_4_1"/>
    <dbReference type="OMA" id="FDRRDLW"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1180.10:FF:000005">
        <property type="entry name" value="Alkyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="269" mass="30669" checksum="E395457E75DC3A51" modified="2013-05-29" version="1">MSEAIAYPSEWYGVLTSWLYDRATRLTLDVLAAGPIPQHIGFIMDGNRRYARHEGKAIKEGHADGFASLQRILECLLKLRVKCVTVYAFAIENFNRTPEEVDALMKLLREKLIEISRKGQLLDQYGVRLNVIGERGMLPQDVQEIAQQVETMTEKTDRAILNICMPYASRNEIAASVRVVIDEKKSGITEHDIDRYLETNARGSPPLDILVRTSGVHRLSDFLLWQSCDTTQIQFTPGYWPDFGLRDLVPIILDYQLKCWNNKVQVALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4T7</accession>
    <name>M5G4T7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="7">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_99554</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="7">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630129.1">
        <property type="nucleotide sequence ID" value="XM_040777598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4T7"/>
    <dbReference type="STRING" id="1858805.M5G4T7"/>
    <dbReference type="GeneID" id="63692660"/>
    <dbReference type="HOGENOM" id="CLU_056632_4_1_1"/>
    <dbReference type="OMA" id="AQRGFHI"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000001">
        <property type="entry name" value="Superoxide dismutase [Cu-Zn]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 7" id="KW-0186">Copper</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="8">
        <location>
            <begin position="14"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="157" mass="16003" checksum="40080C58A0AC6440" modified="2013-05-29" version="1">MVKAVAILRGDSPVTGVITFTQSGEGEPVVVSGEISNLDPSAHRGFHIHELGDNTNGCVSAGPHFNPFTKKHGGPTDSERHVGDLGNITSDDSGKAVINITDKQLSLIGPLSIIGRTVVVHAGTDDLGKGGNDESFKTGNAGGRAACGVIATGLSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G563</accession>
    <name>M5G563_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_50010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630264.1">
        <property type="nucleotide sequence ID" value="XM_040774958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G563"/>
    <dbReference type="STRING" id="1858805.M5G563"/>
    <dbReference type="GeneID" id="63690020"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="HAIPREK"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="39489" checksum="75B06E0D8346C22C" modified="2013-05-29" version="1">MSTTTQPPVQYVRLGNSGLRVSLPIVGCMSFGSSQWSDWVLDEDKALPLLKAAWDRGVTTLDTANVYSNGESEKIIAKFIKTYNIPRSKLVILTKCYGIVAEGQPGFFTATKQYLRDTREFVNQAGLSRAAIFNAVEACLRRLETDYIDLYQIHRYDPNTPAEETMCALNDLVRSGKVRYIGASSMYAWQFAEYNHVAEKNGWTQFVSMQNHYSLLYREEEREMIPYCKAKGIGLIPWAPLAEGNLARPVAKEAHDAEKTSRTDTAVFKKSVTETDKRIIARVEELAKKYNVKMAQIAIAWINTKVSSPIIGMSSPSRLEDAIPVTTFKLTSEDIKYLEELYTPVAIQGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Y6</accession>
    <name>M5G5Y6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_53284</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628099.1">
        <property type="nucleotide sequence ID" value="XM_040775160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Y6"/>
    <dbReference type="STRING" id="1858805.M5G5Y6"/>
    <dbReference type="GeneID" id="63690222"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OMA" id="MIYYLSC"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="445" mass="49151" checksum="0AF2458B2A802786" modified="2013-05-29" version="1">MIPLLMCMYVCGYLDRTNLGNARLQGLPQDVLGGDPTGQLFAWINSGFYFAYVFGQFPGVLGAKKAPLHLWLGGAAFGWGFVCAMQALAFNFASLFMCRIFIGIFEAMFSPNMCIYWTYFYTREEIGKRLGIWFSCANVAGAFGGLIAFGVQNIHGSIHNWRLLFIIEGIPAAFFGLVAMKVLPNRPEKTKYLNDDERKLAILRMSRGALKEEAGSLNWKHVRMAALDWKTYVAGTIYFGANCAAAALGAFLPTIIASMGYSAAQAQLLTVPPYTVGAVVLILTTFGSDHYQSRGIPMIFSTFIGGTGYLIMLCVESNIHVRYFATFLICISTYTTIGLCIAWFPYNMGSESKRAMGNAMYQAIGQCGSILGSNIYPLTQGPRYLTGFGVTCGFAYLSTILALILTVYCRMENKRRDKKYGYADRHAAVDVSELADHAPMFRYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G635</accession>
    <name>M5G635_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626105.1">
        <property type="nucleotide sequence ID" value="XM_040773408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G635"/>
    <dbReference type="STRING" id="1858805.M5G635"/>
    <dbReference type="GeneID" id="63688470"/>
    <dbReference type="HOGENOM" id="CLU_012062_34_2_1"/>
    <dbReference type="OMA" id="PREPAYP"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="97"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="37304" checksum="E70F3EEE6A4F2BA1" modified="2013-05-29" version="1">MSSKRIYIGKMPRDAMKQDIEKFFEGYGRIQDIRIMNGFGFVEFENPKDAEDVVANFQGKNLLGEPIIIELAKESRRERGGGFEERGPRPFTRRPGYRVLIHGVSRDTSWQDLKDFGREAGAVTFSDLDRENPGEGILEYLTPDDLENALRLLNNRELRGVTVRVSRGEGGLGGSGVDYSRDKEFRRDRSRSPGRRGGDSFDRRPPPPRRDYEDRPRFDDRERRDAGRDRYNEPPTRGEDRYADRPPRHDDRPRYDDRERRDAPRNGEARGGYEDRPRYEDRPRFEDRPPRGGYPEDDRPRRDDRDRRDYGRDAPPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6E2</accession>
    <name>M5G6E2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631153.1">
        <property type="nucleotide sequence ID" value="XM_040772109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6E2"/>
    <dbReference type="GeneID" id="63687171"/>
    <dbReference type="HOGENOM" id="CLU_1695407_0_0_1"/>
    <dbReference type="OrthoDB" id="10656956at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17168" checksum="BE58C9CD5DA93BE4" modified="2013-05-29" version="1">MDAGPSTSTRVTVSTKPKPEPRSEPKSEPKPKTKPETIVDPKPRPATDVAPSAVSEHPLPSSPPTEDQLLIKSLRKYSRYVEAYAKIVQQKQIYEDVAAGRRPLDDPKLYSPEQMEPIVRDYQRQHTAIQALYDKMDEMRAAAASSSTPSVGSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6W3</accession>
    <name>M5G6W3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_16219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628454.1">
        <property type="nucleotide sequence ID" value="XM_040771175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6W3"/>
    <dbReference type="GeneID" id="63686237"/>
    <dbReference type="HOGENOM" id="CLU_518757_0_0_1"/>
    <dbReference type="OrthoDB" id="3423247at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="525" mass="56733" checksum="70349762ABF9B1CF" modified="2013-05-29" version="1">MLQLQGLTLETLQSRPATPALQYEINEVDLDEMRFGEACELAGMEQEEEVPNKEIKIDEIEKDKMLANSYLVRATSSQEVDLLDTQNSLDAELETALFNTLGYLNQRAITISAADAAAASTPATTMLLSAANSGPAASAATTVHAAAATLVATAPLAVTQPNQDVVASTATNTLVLVTMHRNASGSPCTSLPTTVSPMTASAVDSIWETIWQSAAAPPRGTNVPAICIQSHPLLPALDDPCECLLTVKQRLAQEGAELVVHKTTKPGRPSLQEHPDWDDSWVKSEWAHLKEPCPPTSALWPQLCNVLHSHAALVSGRSENLSVPDNAEHAAAAPHMQFNNYAHAEQLEISWMEQLQIDKKAVDLQWYMKQELPTLQPLSLLQPTIMLQPTGTLQPTGTLQPTGMLQPTAMGHSPLPALESSNPEPEALSRNAVSGIVQQCQSLDNQGDPDSMPTTFVQFLPWKSNASNVSSSLLLHMQQACKNKGNTEDPGVDSEIPLCTSYYNLLENMHNGMSKAKFNKTPFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G764</accession>
    <name>M5G764_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626500.1">
        <property type="nucleotide sequence ID" value="XM_040768930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G764"/>
    <dbReference type="STRING" id="1858805.M5G764"/>
    <dbReference type="GeneID" id="63683992"/>
    <dbReference type="HOGENOM" id="CLU_2527410_0_0_1"/>
    <dbReference type="OrthoDB" id="3064195at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="8603" checksum="44D7286AD3DB5B14" modified="2013-05-29" version="1">MPAAQPGRSDLLASIQGAGIHMLRKTPAEREEPFSPTAAAPAAPAAAGGSDLAGALAAALSQRNKSLGQESDSEEEDDWDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G766</accession>
    <name>M5G766_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_108188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628554.1">
        <property type="nucleotide sequence ID" value="XM_040768605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G766"/>
    <dbReference type="GeneID" id="63683667"/>
    <dbReference type="HOGENOM" id="CLU_026673_29_2_1"/>
    <dbReference type="OMA" id="DVCQAKA"/>
    <dbReference type="OrthoDB" id="809632at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="333" mass="36567" checksum="6D452B76E45603A1" modified="2013-05-29" version="1">MSLPNPTLIFLSRPLTFPTSTNISLLTPSINLSLPLEGGFLTRTLWVSLDPYMRGRMTSGWEEGSVWSGFGVSEVLRSEVEGLKVGDKLYGHQPYQAYILHPPSERAAYRLLPSPSPIPLSAYLGPAGMPGKTAFYGLKALAHPQAGEKIFVSAAAGAVGQLVCQLCKAWGVRVLGSAGSEDKVRFLIDQLGVEAFNYKEVDTALQLKRFGPVDVYWDNVGGETLDCALEAMNRRGRIVVCGHISMYNVPKEQRYGLKNTHEMIYKELSMQGLSVTPYEQEYADEFYATVPPLIAHGEIKYMEEVTEGLENAAEAFVGLLKGENRGKVVVKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7D4</accession>
    <name>M5G7D4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630994.1">
        <property type="nucleotide sequence ID" value="XM_040768051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7D4"/>
    <dbReference type="STRING" id="1858805.M5G7D4"/>
    <dbReference type="GeneID" id="63683113"/>
    <dbReference type="HOGENOM" id="CLU_1229892_0_0_1"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="1">
        <location>
            <begin position="87"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="25385" checksum="737E98423D2D0CC3" modified="2013-05-29" version="1">MTMYAPAYGPSAYGMQPGWNAATSYPGATAGALVPYNPNTYGTGSPTSALGLYDGFNMGYASNRRPWAYGRVRSTIEFNDWDSNNPFWLLSNSAPLPLYDEQGRFHPTAAHLFHARKFLDPRLADQVSACSTAQGAKELADSWRPYIRPDWRRVNVQMNYADAPVQMEWVIREKLRQNPQFAQLLMSTGRCYLLNTSIDENFWGIGSGRGRNELGRALMRLRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G864</accession>
    <name>M5G864_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arginyl-tRNA--protein transferase 1</fullName>
            <shortName evidence="5">Arginyltransferase 1</shortName>
            <shortName evidence="5">R-transferase 1</shortName>
            <ecNumber evidence="5">2.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginine-tRNA--protein transferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_103351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = an N-terminal L-arginyl-L-aminoacyl-[protein] + tRNA(Arg) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10638"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83562"/>
            <dbReference type="EC" id="2.3.2.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the R-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="5"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633300.1">
        <property type="nucleotide sequence ID" value="XM_040767742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G864"/>
    <dbReference type="STRING" id="1858805.M5G864"/>
    <dbReference type="GeneID" id="63682804"/>
    <dbReference type="HOGENOM" id="CLU_020349_2_1_1"/>
    <dbReference type="OMA" id="KYQTAIH"/>
    <dbReference type="OrthoDB" id="74183at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017137">
        <property type="entry name" value="Arg-tRNA-P_Trfase_1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037207">
        <property type="entry name" value="ATE1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="168"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR037207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="50040" checksum="1BA4D5C6C26CBE3A" modified="2013-05-29" version="1">MTPLSLVSFSSGLSQHTCGYCSPSGERSLLPTSISYGLNPRQLSVSVYQRMLDRGWRRSGTYAYKPDMGRTCCPQYTIKLDALGMKAGKSQKGVVKAWNKFVVEGEKEVVGDGTMQVDVKPVKKKGRDNAPFDLPKAIHASEMSYLPEESTPAHEFEVVLELSSYSEEKFELYVNYQAHAHKEEDKAPSSFKRFLCHSPLIPEDISYPRPPPPGLPKKYGSYHQKYILDGKLIALGVIDILPNCVSSVYFMYSSKVEKWGMGKISALREAMLVREMHEAGLEDLKYLYMGYYIHSCQKMRYKGDYSPSYLLDPEDYTWHSLPTCVPLLDAHQYVSFSHPPEGGQSEADVQGPIDTGLEEMEALEMDGMYDPLPRLMAGCEDPLAVAQDPKMRQVNIVNRQERNTVSVRSVVRSKIWKIPMLRRMVCDAVAALGWELALEVVFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8F5</accession>
    <name>M5G8F5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_87634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631334.1">
        <property type="nucleotide sequence ID" value="XM_040776822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8F5"/>
    <dbReference type="STRING" id="1858805.M5G8F5"/>
    <dbReference type="GeneID" id="63691884"/>
    <dbReference type="HOGENOM" id="CLU_085114_0_0_1"/>
    <dbReference type="OMA" id="MVDNIQD"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="208" mass="22531" checksum="ABAE3DF2BF7A5336" modified="2013-05-29" version="1">MLLTSAARPAAHVISTTLQRRAASQIAIKYAQAAYGAALKVSPATLSKVQTDLAGIVTQLPQQPQLLDLIQNPTLSAGDRKKGLDQLWGTRKDADKITKNLLEVMSENGRLGELEGVSEEFKELVNKYKGELEVIVTSDKPLTPEIMKRLENAMKASQAAKDSKTLKVSNKVNPGILGGLIVEFGDKTIDLSVSNRVNRLNALLQESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8J9</accession>
    <name>M5G8J9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_45575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633435.1">
        <property type="nucleotide sequence ID" value="XM_040774654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8J9"/>
    <dbReference type="STRING" id="1858805.M5G8J9"/>
    <dbReference type="GeneID" id="63689716"/>
    <dbReference type="HOGENOM" id="CLU_174457_0_0_1"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="1">
        <location>
            <begin position="17"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="93" mass="10162" checksum="B217D1E85407FB02" modified="2013-05-29" version="1" fragment="single">IIQLHYSTSTDVMSCAVTDSVAISRPCCAIHNYPLPLPSSHASFCIPHTHLKYVCIFPGCNAPTQLDMQTCDLEEHTAQETAYCTVGNSYALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K0</accession>
    <name>M5G8K0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_117679</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626990.1">
        <property type="nucleotide sequence ID" value="XM_040770433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8K0"/>
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    <dbReference type="GeneID" id="63685495"/>
    <dbReference type="HOGENOM" id="CLU_016785_1_2_1"/>
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    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
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    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="253"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="59188" checksum="EB5523F99884D370" modified="2013-05-29" version="1">MPVPTRPRSPSPSPQHKKLKFTPVALYGILPLGNYLGRPSLPCSLGTLRRLPDELILYLFSLFSPSDLLSLSAVSKACFAFALHEPLWKEHYVSLSEGKLGRWQGTWRKTFLTRLGHAPDLPIWPTDGISCRGIFSDVLYQPQLCASLPLHHYFPSKKQNIPRRPYTSLSPAEFAAHYAAPGEPVILTGALETWAAYTHPSHKWSLSSLANRFPSVRLQAEALSCTFAEYERYASNCAGEDTPLYMFDSGFVESASGMGEEYKPFEVFGEDLFDLFGSERPDYRWLIAGPAHSGSTFHLDPNSTSAWNASLKGTKAWVFFPPQCTPPGVYVSPDEGEVTGPVGVGEWVEAYLKEGWRRFGPQGREGAGLMRIGLQREGDVVYVPSGWWHLVVNLTPCIAVTQNFVSQHELHKVLKFMRDKPGQVSGFKDPKRRDECCEGEEDESGDAYRAGLYGRFVNLLEENEPGLLREALAKLGPVPVGREGEGEGSKVRERKERVVQKEKEKEQGSFRFDFELDFELEEEEVGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U4</accession>
    <name>M5G8U4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632048.1">
        <property type="nucleotide sequence ID" value="XM_040769613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U4"/>
    <dbReference type="STRING" id="1858805.M5G8U4"/>
    <dbReference type="GeneID" id="63684675"/>
    <dbReference type="HOGENOM" id="CLU_086044_1_0_1"/>
    <dbReference type="OMA" id="YQRKGWG"/>
    <dbReference type="OrthoDB" id="9975416at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051822">
        <property type="entry name" value="Glycosyl_Hydrolase_84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13170">
        <property type="entry name" value="O-GLCNACASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13170:SF16">
        <property type="entry name" value="PROTEIN O-GLCNACASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="66"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="25326" checksum="098F5648548971B7" modified="2013-05-29" version="1">MPLSLRPGTPADAPSLSKICLLTGNYGTSAEHLHSRGELLGLVYAEPYVLRDGTFAFVLVDSAEREEGEEGTEERKEEVVGYIIGAYDTALYEAERGRDWFPLLAKKYPVGSEGTDADKYYYGLFASPPKTGQDVLSIYPSHLHIDILPAYQRTGWGRKMVHTIIEHLSSKGYKGVWAGIDSRNEAGRRWYIKLGFRRVESEVGEYWVMDFDRWDGIRGRPVEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G940</accession>
    <name>M5G940_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Macrofage activating glyco protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631584.1">
        <property type="nucleotide sequence ID" value="XM_040771898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G940"/>
    <dbReference type="STRING" id="1858805.M5G940"/>
    <dbReference type="GeneID" id="63686960"/>
    <dbReference type="HOGENOM" id="CLU_036093_2_1_1"/>
    <dbReference type="OMA" id="LCQNAYL"/>
    <dbReference type="OrthoDB" id="2564904at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="37138" checksum="6ACFAA7305712806" modified="2013-05-29" version="1">MLALLLLAGSATAQYSATYIPADAPDQSQVGQIGTNQCGTTNSQGSLCQNAYLNGLDDFCLFAPPWTNGTNSTIGATEEDEVSWCMRTGYGTRTIPDGTITGAHWVQTPLYVQITGFGDLTKLNIPAGDGGGELDPHSWTGLGNPQGGLVFGTTFGGIQQYHEWTNFMSADEFCFRACVDGPEATTYCQHVYDEQGCEWNMPANYDIGTFTSCQADDGAPMGVYGSSTWDSNCQHTACAGGTPSAQAAPSSSMCSSVNSISNLAAVAPTATATGPFTFDSAALASSNSVASTAVTTSTTSSSSTSSGLATSKSSSTGGSGTATVSAQGSPTVSPGSTARGSAVGLELPFGSVLALGGMVLGMLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9B0</accession>
    <name>M5G9B0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_89866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627275.1">
        <property type="nucleotide sequence ID" value="XM_040776937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9B0"/>
    <dbReference type="GeneID" id="63691999"/>
    <dbReference type="HOGENOM" id="CLU_1896149_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="134" mass="14590" checksum="A8ED90C1F86A791F" modified="2013-05-29" version="1">MPSATEPNLILDGYALDVVAWQRWIDFHPQVGGKRDLSTLLALTSHRVNSTPGGTKINLYPLHGEDVDGNEVVVGLLFVPPTSRGDGKETAEHKELMNRVLAGSSLKWSDLKWINAEALMDRDAGSWASGPRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9L6</accession>
    <name>M5G9L6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627405.1">
        <property type="nucleotide sequence ID" value="XM_040768684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9L6"/>
    <dbReference type="GeneID" id="63683746"/>
    <dbReference type="HOGENOM" id="CLU_1234988_0_0_1"/>
    <dbReference type="OrthoDB" id="3269637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="53"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="224" mass="24968" checksum="6232E804D911F13B" modified="2013-05-29" version="1">MSAAAGRIWPPEDINGRLVLNLDVIRERPSQSSHLSTRDKRFTDAVGQRDKVCILSGRHGNFCEAQHLVHRHIGNQGMADILSRNSPQPLDSNFEPIREVDDPRNGVFMDRGLHSRYDAGALAIMITPNCVLDTSDIVAPAPRILEPGTACPAHVRYTAQWFDMASFDEDVVDGVPENTDAALGLSLLKSWIAWQSLDRAPSRVTMKTIRTKSSKFRGVYNRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9N8</accession>
    <name>M5G9N8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629476.1">
        <property type="nucleotide sequence ID" value="XM_040772481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9N8"/>
    <dbReference type="GeneID" id="63687543"/>
    <dbReference type="HOGENOM" id="CLU_1917009_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="132" mass="15051" checksum="7C698680105DB66F" modified="2013-05-29" version="1">MDVDDLEDRFNAFPDGGLEILLRCYDVPAIPQLVAYHPPSDQLLAGVAFESFDMLYGVQEGEAIDDWTVNSYTLFHGDSLRLPDLSINSHCCDVNIDRLYSDMTLALERDKLRNINPPTWRSALSRFYPTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA8</accession>
    <name>M5GAA8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627725.1">
        <property type="nucleotide sequence ID" value="XM_040773121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA8"/>
    <dbReference type="STRING" id="1858805.M5GAA8"/>
    <dbReference type="GeneID" id="63688183"/>
    <dbReference type="HOGENOM" id="CLU_1288863_0_0_1"/>
    <dbReference type="OMA" id="GDHVYTI"/>
    <dbReference type="OrthoDB" id="4095724at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067596" evidence="1">
        <location>
            <begin position="19"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="214" mass="20648" checksum="9ABA15FEC40A1E5A" modified="2013-05-29" version="1">MICLRHAVLLALSLPALATPIDVEEREIEERQFGILTSIFGDATGFLIGTVGAAITSVGGEAFTILTDGAGDALTLAESGVGFVTSFGGSVFTVATAGAGEVGTIVESAAQGAFTVVTSIGGEGITLAENGAGIVTSFGDHVYTIATAAAVSGASELTSAAGSGPTTSGSTTLTSPTSTASSAALGKAAGLGKEHLLGVGAVVMGVVVGAWAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC2</accession>
    <name>M5GAC2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627745.1">
        <property type="nucleotide sequence ID" value="XM_040773127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC2"/>
    <dbReference type="GeneID" id="63688189"/>
    <dbReference type="HOGENOM" id="CLU_1845020_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="139" mass="15736" checksum="06FE5550B89696A8" modified="2013-05-29" version="1">MRTPTEAGFLPPGLLDWACDAESQCLEFAAFIDAIKALPAGAWKERDAENIDPAEIARHARELARIYSQIIYCTKIKEEASTPATEAEHRRPIYAMLDLCCTLPDSGDSSFTRLRRENTIESPRPEIQSISFSIRMKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAF0</accession>
    <name>M5GAF0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632703.1">
        <property type="nucleotide sequence ID" value="XM_040771835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAF0"/>
    <dbReference type="STRING" id="1858805.M5GAF0"/>
    <dbReference type="GeneID" id="63686897"/>
    <dbReference type="HOGENOM" id="CLU_501539_0_0_1"/>
    <dbReference type="OMA" id="SHQHECE"/>
    <dbReference type="OrthoDB" id="3363386at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="543" mass="59062" checksum="8894ADA6587FC567" modified="2013-05-29" version="1">MHHPPRALTPTSNSSEEDKQNPLGTPRKIRFAPFPDPRRAIAVDEDGKEVEMVEDEGTISFGITKDASPPVSIEEQLASSRPESIASTEEAEEYTATRKERPRSWGTATKSFLSPFLAKSSSKGGFLSPDTDDGEDYMSTKLTRRTSTGGLSGSNPDRFQWEVKRAEEFLGGSALKQMISANSDVENPSRSHTRAHSADKRRMLLNGRVYGGGRQKQEKYTEPEFVEWGYGGMGSQKAAAQTRWQSVQGKTVYNSGGNSRGVDEDSDDGSGMAWVRKRRRERELKAQMEKEKEQAKNGQENENVPQAQSVPPISTNAKTQPSAHSSTRTTPTASTLSSALSSRSQSPQPSIGSAAANSGIATGASTPHVDDEHHYRAVSLPPPTTHHHHHHLYKHHGDKDHRPLPPPLAPVTAIDAINQQDMLGTEAGIGKANTLQLELTPATPVSPEHEENKLSLQQANSMHVPNPHVVESSESSDSESSDEDDDDDDDDDDEPGIAREKKRVASSETDSTESDVEDAPDNKPRLTSASAGVEKVSTKGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAF7</accession>
    <name>M5GAF7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_62495</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632713.1">
        <property type="nucleotide sequence ID" value="XM_040775700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAF7"/>
    <dbReference type="STRING" id="1858805.M5GAF7"/>
    <dbReference type="GeneID" id="63690762"/>
    <dbReference type="HOGENOM" id="CLU_008721_4_2_1"/>
    <dbReference type="OMA" id="WNPFRHV"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="caca2"/>
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    </dbReference>
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        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="224"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="40957" checksum="B4E0D3984DB390EF" modified="2013-05-29" version="1">MSILTIFKSSWLNLLLVFIPIGWALHFVNVPPIVVFVTTFLAIIPLAALLSFATEELAVRVGETLGGLLNATLGNVVELIVAIIALAQCKLTVVQSSLIGSILSNLLLVLGMCFFAGGVKYSQQEFLVTPSQINSELLFLSVVAVLLPGAFNFAVQSSNNSDNNPNDDVSASVLGADILKMSHGVAVILLFIYICYLVFTLWSHASNSAEQEEQTLQMNVPVTFALLIIVTILVGVTAEFLVDSIDGVTATGGISEEWVGLILLPIVGNAAEHVTAVTVAMKDKLDLSIGVAVGSSIQISIFVIPLTVVLAWIMNKPLTMLFDPFESVVLLLAVLTVNYTTQDAKSNWLEGMVLMMLYVIVAVSFWFYPGYNPSQTLNLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAX5</accession>
    <name>M5GAX5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_12843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770951.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63686013"/>
    <dbReference type="HOGENOM" id="CLU_467697_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="583" mass="65312" checksum="09337AFC59ACB07E" modified="2013-05-29" version="1">MATRMSIAEEGDDNSHGGSSPPLGSGSNFGTQSTSQKGATSDTLVNPNGGPQKDDLEKSDLPTGSYPTKDYNMQGLDEVVDVKAEAWEPLLFLVNKGVPIVNLWFSSLDLVITFTVDQRAISFKYDPQSMAWHQQQVWLLLPSFFHHPNMDDTAIISTHPDAFLTVQWLNKDQLHIERVSNGQKFCLTTDGSFAALMTQYAQTPYCKVLAWFIDTTLMVINYDFGCIDFYHGLPEMCEGPMDDNLSPTCHSHLKAPIFAAKLVFGDEGPLLTVKLNMCFSVYVIRGLATSPVQGVQARISLQHVWTVYTHVSPPVPEVSHITDFDLTDGSIDNNSTITPYDATGVIVTLDEHNLIRHLDFIKFHGRAIYMGRKHSCLWIKVPFHLHVKDIPEPIPVNKWQSRHPVIVQDDQVFYVHDVPALPSYITNCGLNQYLDMKTSVLLGDDWYLKYGASLTQVTQLVLVWPSKDAFVSIILAKLPGGDQFFRLERTYDGGSIWDNLALVAWNEPQWQNCVDTSHFSPTDNSLWALDFDQLSTKDCAESECQLIVQGIKGLDKDEELGPQARLAWIWLSYGAIAQAIPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBP8</accession>
    <name>M5GBP8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630381.1">
        <property type="nucleotide sequence ID" value="XM_040772215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBP8"/>
    <dbReference type="GeneID" id="63687277"/>
    <dbReference type="HOGENOM" id="CLU_3014103_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="56" mass="6471" checksum="BE433E2F5C8BF55E" modified="2013-05-29" version="1">MGLTDVYPTSAPNDKRQPRERQPDYPIAGFGGKVATSFRVRRVYQLTTPYISRLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBW4</accession>
    <name>M5GBW4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MBOAT-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_113187</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633383.1">
        <property type="nucleotide sequence ID" value="XM_040769583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBW4"/>
    <dbReference type="STRING" id="1858805.M5GBW4"/>
    <dbReference type="GeneID" id="63684645"/>
    <dbReference type="HOGENOM" id="CLU_011340_5_0_1"/>
    <dbReference type="OMA" id="WHGTRPG"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="406"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="568" mass="64784" checksum="10FB2FAD00611D27" modified="2013-05-29" version="1">MLMDSIASRLHSITGAPEDQIKVFIFFTLNYPLGHLYIRIPNELPALRHIFSIFISLYALLELKLYSGIAHELFSISGVWVLLRWKHKYMPWAVFFFAMVHLMYNHLYRIWFHLSVENFDITFSQMVLVMKITTLAWNIHDGRQPDEFLDQQQKESRVVQFPSLLEYLGYCFYFPGFLVGPSCDFHTYRALCSGTLYTPREGKAVPAVTVLEGRKRSAYYHMAIGAVNIVIWLTCNSRVNYFQVMQEGWEKQAFVKRVFLVQLMGIVQRTKYYGAWKLSEGAAILTGLGFNGYTRDGKTLWNRATNVNILNVEFAPNIKLLLDNWNVNTNVWLRHCVYKRVTPRGKKPGFRSSMLTFLVSALWHGSESGYYLTFIQGGFVQTVARMMRSCVRPFLLPPVVEIRRATTDTEPSTRAATPAPEDGVSPVPGTPISGVPGSSGGKVFVPPPPPPTLIKRIYDILGMICTSMELNYCAAPFILLTAKNSLLGWGKMGWYGTWMSFVPLLFFWLGGRPFLLGKLKQRAEKEKRRLERIEHLPGVVVVPPSPVITKADEVEEFVDQGWTATKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC67</accession>
    <name>M5GC67_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Translation initiation factor 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_97692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632984.1">
        <property type="nucleotide sequence ID" value="XM_040777474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC67"/>
    <dbReference type="STRING" id="1858805.M5GC67"/>
    <dbReference type="GeneID" id="63692536"/>
    <dbReference type="HOGENOM" id="CLU_1094243_0_0_1"/>
    <dbReference type="OrthoDB" id="21573at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070124">
        <property type="term" value="P:mitochondrial translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938:SF0">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="29017" checksum="E87C2847974CF16A" modified="2013-05-29" version="1">MAFQQVASCIASTSRSVLRTSTRKRIHPTGVTRSAIFPLYPHYSTQRKDVYPAQELLKTITPLNPFNSPMEQERDKDENALPRNEKIKFEMVQLIDRETRTLGPLRPLVDILAEIRKGKEFVQLVSHERPLVKIITFDEDRRAERTRKTQQRAARAAGRSKEVQISWQSEAGDLAHKLDKVREVLAEHNRVSVLLSGRPKTPPPTDEKRAEMEKKVYKVAEAMGAFEVGEPERGRRHSILNFRPKTSAGSEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCF9</accession>
    <name>M5GCF9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628645.1">
        <property type="nucleotide sequence ID" value="XM_040768480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCF9"/>
    <dbReference type="STRING" id="1858805.M5GCF9"/>
    <dbReference type="GeneID" id="63683542"/>
    <dbReference type="HOGENOM" id="CLU_746009_0_0_1"/>
    <dbReference type="OrthoDB" id="18679at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15886">
        <property type="entry name" value="SNARE_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="371" mass="42784" checksum="A40FCD100EBB6504" modified="2013-05-29" version="1">MFWFKANSLNPPVTGERHAKYNTTDAFDTDTTRIPGSTSRTGVRKYDPPVNATCNSLDCDLYPTPTASPSNEPEAHRQIVLDPYELPSLRPDFLEQADLVALRCSRAQDTNPKRCYRCMIAFDHGEDQLQTRVQMDEDEEIEYLKKEMRRMKQETVISSQNVLRLAREIEEKAASLLRKVSSTSAPPISNGPRTRRQITLDPYRLLDRHDPYDQNRAELSGALDMEAQVARAVSRYNRSVPRVHNANDQLLSQAQKMSDKEIEAMKKDIRRMKQETVQLSRDALRSAREIEEDARITMFMLGDRIEKLVDISRLSGPPDPFLRRVRQSEPAICEITDKENERHEGDSLYIGFCKSMQHVWQMQRLARSDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCJ7</accession>
    <name>M5GCJ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_107546</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628710.1">
        <property type="nucleotide sequence ID" value="XM_040768497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCJ7"/>
    <dbReference type="STRING" id="1858805.M5GCJ7"/>
    <dbReference type="GeneID" id="63683559"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="LRWAWRI"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="545" mass="61296" checksum="80BA4C68AB3F95D1" modified="2013-05-29" version="1">MFSYFDLSRIPTLGLIVLAVIAAGYTLRGLWQFSRRFFTPIRHLPGPSRRSWLWGNAAAVLQDDACLCEWTEQFGVAYRLPSMLGKCRLNTIDPRAVGHILSHTDIYPKAEHARTLLRAAIGEGLVVAEGDTHKRQRKIMNPSFAPIQIREATPIFFEISYQLRDVLNELQGMAVSTQGVELDMFAWIGRASLEIIGLAGFGYRFNCLVDESNELFHAYHDMEQELGRNPLTDLLKDRFKFLRRIPGFRNPVMDAALNTTHRVGTELVMKRKAEVFEEMQSKFGQNGKIAGRDVLTALIRANMAAGVSENQQMSDREVLAQISTFIIAGHETSASAVTWTLMSLAQYPEVQGKLREELSLVSQDMPTMDDLNALPYLDIVVKESLRLHSPVHYSLRVAKQDDTIPLLHPIVDRYGRKLDHLRVQAGDFVGVEIMPMNRSTALWGPDAGDFRPDRWNEETTGAKEISGVYAHTLTFIGGPRACIGYRFAITEMKAILFALIREFEFVPVPGKEIAVKNVIVARPYVKGEGTRLQLPLLVKRVSRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD43</accession>
    <name>M5GD43_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629025.1">
        <property type="nucleotide sequence ID" value="XM_040775040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD43"/>
    <dbReference type="GeneID" id="63690102"/>
    <dbReference type="HOGENOM" id="CLU_3050271_0_0_1"/>
    <dbReference type="OrthoDB" id="3267566at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="5921" checksum="17C14D1D3A4AA11E" modified="2013-05-29" version="1">MSQEFEARAVLNSGATGLFIDMSYIEEYNSTTMLLECAQPVYNVNGMPNEAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD66</accession>
    <name>M5GD66_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633524.1">
        <property type="nucleotide sequence ID" value="XM_040767783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD66"/>
    <dbReference type="STRING" id="1858805.M5GD66"/>
    <dbReference type="GeneID" id="63682845"/>
    <dbReference type="HOGENOM" id="CLU_2305995_0_0_1"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10605" checksum="F0364F0040DDA6C3" modified="2013-05-29" version="1">MALVSILPRMSPHPASSLGGNADLASKARVVAWWDRYLAGPASGQFGANVKPHLKIVSVSVFTEHGCDVHEVVHEATVSEAFLNCNGVMHGGCTAFIMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD77</accession>
    <name>M5GD77_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631216.1">
        <property type="nucleotide sequence ID" value="XM_040772126.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GD77"/>
    <dbReference type="GeneID" id="63687188"/>
    <dbReference type="HOGENOM" id="CLU_003293_1_1_1"/>
    <dbReference type="OMA" id="DHAGQQV"/>
    <dbReference type="OrthoDB" id="10027144at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd22408">
        <property type="entry name" value="KH-I_Vigilin_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02394">
        <property type="entry name" value="KH-I_Vigilin_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="192"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="285"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="371"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="524"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="610"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="697"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="782"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="868"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="941"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1022"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1234"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1159"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="587"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1210"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1307" mass="141267" checksum="0A5EAB5486AF63E0" modified="2013-05-29" version="1">MASSNSISAADLARMHGANPATVGGHEDIVDPFPSLGGGEPTPAVRASSSRPTQAPSGALDTASEAAFPSLAAPALRQPDKAPAKSKWTAGSAAVKGKGKAPAGKPNGTASPGPAIAKQVLPTDTLVIESPVLQPKQSVGDVCRIVMKKHGVNIDPSSQMKSGRKETTFLIKASTAKLVEEARKSLVSMLSPVITLTIDAPVSTIGRIVGPKGAALKALRDEFNVRVDIPRRETLHTNGDAATLPANGDADEVEEPTLTVTINGPAPGARHAYAHIHAIVAEKTSRTSTKVPVPRQFWPFLSAKKDELEAGQDVKITIPKPYHPTEEDDDATAAEKSHAVHSAPVIISGERNAVALAADRVKAMVNDLELNTKELAYKFPKRQHRFLVGEAARKIVEDTGCSVELPAFDDPSEEVVIRGPEDQLPIALGAVMKQANTASVLQVDLNKIYPTPPKHAHQLLMFLTRSGRLRKLGEAHPGVKFFAPRQALVDSTGGHVVIDIVGDNKALVQKGRDDLDAAVKQLTAECFDSIEIEPLTHKFLIGKKGQKLRAFQDAHGVDVLFPHEGSDTSTVLLVYTHPMEGDKKTNEAEIRKRLAEVKAEMAAMEKEAADMKTETLKVDKKWHRFIVGQGGTTLNGIIGEEKAIIIRVGSNNKPGAHVKDNVDEDSIVIRGPKDQVERATKEILQIVEDAKNDDIVNGFTEEFHVNREFIARIVGTGGSSIKKIRDELGVRIDIDEQEPAGEEVKGKKKKAPSTANIKIVGRKENVLKAKERISEQVDRMADETTEILKIPAQYHPSLIGQGGKYAIRLEEKYGVKITFPKEKEENDAEGRKRDPHVGKDEVLLRGGRKGVAGVKAELLETVEFEKETNNVLKFTVPQSAISRIVGKGGQQINEIKDQTNTHIDIDRENKGGTTGITVKGGKKETEAAKKAILAIAAEVDDEVTVIVAIEQKYHRTIIGVGGQGLRDLIGRCGGPADPRTQAGLVQFPRQGESQDEVRLRGKRVLVDKIKVELEKVAEGLRDRVVLAVSVPIAVHSALIGRGGKRLQELQESTGAQIQFPGSRSYGAVGDAENADEVKDSEPQDVVKVYGSRAACAKAIAEIKKGAETFAASPAHNRTQRAPQETSVKAVPLKYHHVISQGGAFFRSLRAYGVTVDHSTVPEKPEIKPPTGGSQEEARIDQPVSPSEGAQWDIVPNYQHMPEGDAEWTIKAKSKEGLERAEKELEEAIKHAATYTHIGFLTLPNRTMFPRIVGSKGSTITRLREETGANIDVGRDNNTIMITGSEDSINRAKEVIEKILEGGRGRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA4</accession>
    <name>M5GDA4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Phosphomevalonate kinase</fullName>
            <ecNumber evidence="3 13">2.7.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_48719</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP</text>
            <dbReference type="Rhea" id="RHEA:16341"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:16342"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.2" evidence="3 13"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631286.1">
        <property type="nucleotide sequence ID" value="XM_040774863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA4"/>
    <dbReference type="STRING" id="1858805.M5GDA4"/>
    <dbReference type="GeneID" id="63689925"/>
    <dbReference type="HOGENOM" id="CLU_022059_1_0_1"/>
    <dbReference type="OMA" id="LVIHRTM"/>
    <dbReference type="OrthoDB" id="10262935at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004631">
        <property type="term" value="F:phosphomevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016005">
        <property type="entry name" value="Erg8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035102">
        <property type="entry name" value="Phosphomevalonate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31814">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31814:SF2">
        <property type="entry name" value="PHOSPHOMEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017288">
        <property type="entry name" value="PMK_GHMP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="14">
        <location>
            <begin position="169"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR017288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="498" mass="53213" checksum="8497A410DF3FA67B" modified="2013-05-29" version="1">MSTTVVSAPGKVLIAGGYLVLDPAYTGVVVSTSSRFYTVISDGNGFNPGRVTVKSPQFTDGLWEYDVNVKGEEVEVVQVQEGEHRSILKPRNKFVQLAIQRSLLLALELKGAASLESSLSKGLNIYILGANDFYSQRSALASLNLPRTLEALHKLTPFRPCNVPISQVHKTGLGSSAALITSLVCALLLHAGVVSTSELSKAELTHDRKLVHNAAQYVHCLAQGKVGSGFDVASAVFGSQLYRKFGPAVLEPLMGDSVHAKLLAETLRPENPKWDHEVKPFRLPPGLRLMLADVDAGSDTPSLIGKVLSWRKNNVEEALHVWTAISEANSCLAVSLNELSELNDADPATYTAVFTKAAALIKAKWSTAFEDPASDKIVNVLSEVATATEDIRSGMRQMGILADVPIEPDEQCRLLDACIAVPGVIGGGVPGAGGYDAIWLLVIDGGETQGALSTVEGVWQSWTEMSVSPLMAWESHEGGARVEKIENVPGLVEAIGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDP5</accession>
    <name>M5GDP5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_47605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631581.1">
        <property type="nucleotide sequence ID" value="XM_040774768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDP5"/>
    <dbReference type="STRING" id="1858805.M5GDP5"/>
    <dbReference type="GeneID" id="63689830"/>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="42"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="33935" checksum="A320798F43CC5E50" modified="2013-05-29" version="1">MPRAQVCTGVDVDAVAGALGSYGGENSPSDIARGMFAGQAGSSRLLRLFSKYGIKTSWAIPGHSWETFPEEMSAVWEAGHEVVLHGYSHENPIAMTPKQEADVLEEQLATKYCGKAPVGYVAPWCENSPQTSALLLSHGIEYSRTNMHRDAEPYYGRVGHTWTKIDYAAEAKTWMKPLIRGTETGLVEIPTSWYLDDMEPFMFIKQFPNSHGWVDTRVVENLWKDQFSYFYREYDDFVFPITIHPDVSGHPHVILMLERFIEWVNTHDGVQWVTMKEMSDDFKRKNPLPGRGNGLPVNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE00</accession>
    <name>M5GE00_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L28e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_94506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629742.1">
        <property type="nucleotide sequence ID" value="XM_040777226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE00"/>
    <dbReference type="STRING" id="1858805.M5GE00"/>
    <dbReference type="GeneID" id="63692288"/>
    <dbReference type="HOGENOM" id="CLU_106801_0_1_1"/>
    <dbReference type="OMA" id="WMIIRNC"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eL28"/>
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    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16000" checksum="47DB14BEC08E1622" modified="2013-05-29" version="1">MSADLEWLLIRKWNSFIVKRVPEGPVFSTEAGNLRNLHSGKYSGIANNKVLDIAEEKGQIVIKTRDASAPISANKKAVKTERVRSRSGGRRVAGVVSKKIASGYRPDLRKAALARASALLEAQKSKKEFPAREIRGKKAKSFGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEA5</accession>
    <name>M5GEA5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040769623.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26879" checksum="A338279385FB88B8" modified="2013-05-29" version="1">MKDALEILGFGPCHHMASLFADSNGRHIDTFLQARTGKRVHWRRQMAGFGSTVDHPTTDFALELIDTFPDALVILTVRDSADVWWKSVQDTIYWGPRWQTRMACWSLPPTWKMARLSRDIGNWYRRNYGSLGPECYTKHNARMVELIPREKLLVYNVKEGWEPLCAFLGVPVPTVPFPRKNDTAEMKRLLRVGTMLGVIFWIAELGLVGWVIHQVIKRRLWDLFNLRTALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEN9</accession>
    <name>M5GEN9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_77042</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEN9"/>
    <dbReference type="STRING" id="1858805.M5GEN9"/>
    <dbReference type="GeneID" id="63691308"/>
    <dbReference type="HOGENOM" id="CLU_002678_91_2_1"/>
    <dbReference type="OMA" id="MLTGEGY"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Transcription factor IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="253"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="463" mass="53238" checksum="A1480461BCBF80DA" modified="2013-05-29" version="1">MQANDTPDLGLSRLRVQGGGVSTPARASFVLVNGALVQNEKKKKAKNYACTWPGCAKAYTKPIRLEEHERSHTGHRPYHCEECGQSYMRDTHFSAHLRSHRPDLEKPYVCTEESCDKHFWTSSQLKAHAATHRGEMPFACDQCEDRFAKNAQLRRHVAVKHCPPGTKVFRCIHEGCTKSFAHSAKLRAHERKHDTERYVCSHPSCSSLDRFPTWTALRRHVQEAHPPTCPYKMCRGKMFSRKDNLRAHMKMHEEGHALDESGEESDESDEGRRKRRKNGGEWKCGEDGCTKSFRAQAALNKHKQISHLGLRRFACNVPKCEYTCGYKHVLQKHIQRHHAPVSAANDVDPEHRERIKVEQEDILLSADNRFIPVPNVCAQEPSPEDIISLLTGAPRHVQPARRILPCPFPDLLEQPFDTERRGTCVWTCSRVYDLWRHLRREHGFDCERSVLETWVKEGEERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ9</accession>
    <name>M5GEQ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630387.1">
        <property type="nucleotide sequence ID" value="XM_040768125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ9"/>
    <dbReference type="STRING" id="1858805.M5GEQ9"/>
    <dbReference type="GeneID" id="63683187"/>
    <dbReference type="HOGENOM" id="CLU_997546_0_0_1"/>
    <dbReference type="OrthoDB" id="2914220at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31382" checksum="59C202B44C81A8DC" modified="2013-05-29" version="1">MPFTLTPALKSTADIILCCSDGVQFVVHSAVIRYASASFAETYDLPAKVEIEHLRVNIYETSSVMDFLLSKIYGLPPSSEPTNIDILIARMKVASTFNMHEITNDRKVELLGTDYLYRRPLDLLAIGMDHHLPELVGQAIEQTFKLSEDKLLNSPMQILPANVPSRLLTARHDRARAIHSRLEGFISGPNREVYGLPTCPRCQSTHPWLVSWIAAVKLELLDLPTTSTIFSPAFVNNVQDDYIQHCDCRVDANTSSHEMMNKLKAIIDPEFPIPTSWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEX0</accession>
    <name>M5GEX0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_20150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632661.1">
        <property type="nucleotide sequence ID" value="XM_040771819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEX0"/>
    <dbReference type="STRING" id="1858805.M5GEX0"/>
    <dbReference type="GeneID" id="63686881"/>
    <dbReference type="HOGENOM" id="CLU_030051_1_0_1"/>
    <dbReference type="OMA" id="HETGNEM"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067662" description="mannan endo-1,4-beta-mannosidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="119"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="576" mass="64093" checksum="5BD4EDDD0C7E4078" modified="2013-05-29" version="1">MQTIIQSLLFGLSIAIGVNALALPAPTHAARAFAPPAVPSSNSANVDPSNLPNYGFIRPSNGHLYDGLGNLWDFATFNSPHLLTCEPFEVVDTMRTLAAGFARPVSRTYVLQVTSINIPADQAHIVSWDNTTMDWVYNEAMFQKMDFVLATAAQYGVKIVHPIINQDYGSQDTNYAGNWADLIRMRYGFATYEDTYAVNWFADPIMLESFKLIINYYLNRINTVNGIRYGDDPTFLAHETGNEMNYLGYLPAPGNWTVAVATFIKSLAPRTMVLDGSLARNNYTDQSFALEALQSPLVDLFSYHYYRDNPPAYDYRRINADSAYVQSFGKTYVVGEHGFYANYSEFSDFFYRQKESNTAGSMVWSIRPHSAEGGFITHGEGDGIFSYHAPGWSPQQTADFDPLELGIIHITRNASYTMVNNNVPAFFPIPNAPEIWVVNNATAGTGLSWLGGAWAQHYEVWAVQFGNLFWTKIATYVLDDVDAGTAYFPIDVYAPEQATTITYSALPTNAPNIPWSDPKLPKTTGHPGWLPFKRDQMGEARDTPQPDLGWKSGFYVMRGVSVDGIPGPFSNVVIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF41</accession>
    <name>M5GF41_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_77571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630712.1">
        <property type="nucleotide sequence ID" value="XM_040776277.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5GF41"/>
    <dbReference type="GeneID" id="63691339"/>
    <dbReference type="HOGENOM" id="CLU_000809_1_0_1"/>
    <dbReference type="OMA" id="GAVHLHQ"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055227">
        <property type="entry name" value="HRQ1_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22982">
        <property type="entry name" value="WHD_HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01075">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="330"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="552"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1081" mass="120981" checksum="7C99C53D51534960" modified="2013-05-29" version="1">MPERSSKRKAAADFIASIEQSGPAAKKAKAAPRRKAPQVDAGPWPEYFKGLEKLFKSLNTVIAFCHARKHLAVTFDTIRSSVEGLIKQPLDLARVAEIKAIIPDLVRFAYVEAESIRVHHDREVASSSYSRKSGRKGSPDFQLAPAEDPSRCEHVLVLDFVETNKNTQKIKEAAGKFSAPPALTQQQLMKLIEKRSQSFTRAVNELLAACAANGDDPVRLVQDAARAHVPVHPLKRTRPNDVQEEESANSGSNQPPKVVPDPQLRLPIDTIIKRLTEDEHYKGQIVKRREFQAKDAVWGRLNRTLSPAIKEALLSARKVEGFYSHQAAALNAIWDGKNVVVSTSTASGKSVIYQVPALCNLEEDKSSTAIFIYPTKALAQDQLTGLQQLLVRVHGLEGIMIAAYDGDTPKDRRQNIRENASIIFTNFDTLHASILPNEDTWRHFLRNLKMVVVDELHYYSGLMGTQVSFVARRLRRLCAAVGNRRCVFVSCSATINDPRGHMMNIFGVDDVEVITDDGAPTGHKDFLLWNPPFLDEMDPALGRSSSMQEACYLFRYLMKHGVRTILFCKIRRTCELVMKSIRHQLTAEGRQDILDRVSAYRGGYSVADRRRIEKDAFSGHLLGIIATNALELGVDIGTLDAVIMLGFPFGIASLRQQAGRAGRRARDSLAILVGDSLPIDQHYMLNPDEVFEKPTEPLIVDITNEGVLESHLQCAADELPIRLQDDGKYFGPCFEEVCKSRLICDKEGWYTTHPSYKPRPTMMVSLRGIQEDKYTVIDITTQDEQHGAARVLEEIELSRAIFETYEGGIFMHQGLTFLVREVDHDTRIAKIARADVNYYTKPRDFTDVDPSQTYRIREIKDSQQRSYFGRIVRKTVVFGFFKMRETTILDTVDLDSPPFIRSSTGFWIDVPRPTLNLLIDKDINPAEAIHAACHAVLSILPVFVLTALGDVGTECKAPQKEYMQKESQRKRPARLIFYDGTAASGICAKVYDRTHHVLAKALEILEHCGCEDGCPACIRSISCTEHNIVQNKIGAQIVLRGVLNLPIDADSIVPQYNRYHITVVEAEPVGARGIPLEPDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFQ5</accession>
    <name>M5GFQ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 10">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_20897</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631222.1">
        <property type="nucleotide sequence ID" value="XM_040772130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFQ5"/>
    <dbReference type="STRING" id="1858805.M5GFQ5"/>
    <dbReference type="GeneID" id="63687192"/>
    <dbReference type="HOGENOM" id="CLU_010467_0_0_1"/>
    <dbReference type="OMA" id="IAHMFIR"/>
    <dbReference type="OrthoDB" id="7939818at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000002">
        <property type="entry name" value="Glutamate--cysteine ligase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000001">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="524"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="528"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="745" mass="85307" checksum="A4FC84D80234E2A2" modified="2013-05-29" version="1" fragment="single">MGLLSLGTPLAWADSIPYHDHVRQHGITQFLHAWDRLKTREGDDLLWGDEIEYMVVAFDDEHKVARLSLRQSEILKKLAHVVEELEEEKSPDTPPIPTFHPEYGRFMLESTPGKPYTGSLKELLTVEANMRYRRKIARRHLKPNEVPLTVTSFPRLGTQGQFTEPYFEPKSEESQSLFLPSEITNPFARFPTLTANIRRRRGHKVAINLPIFEDTHTPKPFIDPTIPWDRALFPGDSEAKDGAALPDHIYMDAMGFGMGCCCLQMTFQACNVDEARRVYDALIPVGPIMLALTAAAPAYRGYLSDVDCRWNVIRDAVDDRTEEERGLKPLEHDRYRIPKSRYDSVDSYLSMDYNNRPEYNDNPLPIDEGIYNRLRDHGLDDLLSKHIAHLFIRDPLVIFSEMIDQDDLNSTDHFENIQSTNWQTLRFKPPPANSPIGWRVEFRSMEVQVTDYENAAFCIFIVLLSRAILSFDLNFYIPISKVDENMKTAQKRDAARKDRFWFRKFVYPQDRAFELRHAVEACQGQGWTGTPTPAATPAATPGPSRGSSPPTSAVHTPLTPLSPISPPRTNGFPPHTHTHQHQHQHQHTQDERSRPVSASQSRCPSPGLPERGPVEEEYELMTLDEIVNGKEGYFPGLFGVVAVYLNSLDVDFHTKRSLYKYLDVVRRRANGSLMTCASWMRRFIRSHPDYKFDSVVSEQINYDLMKAFDEIERGVRKEPDFLPSSYRGDTAFHGHLNTHADQASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFR9</accession>
    <name>M5GFR9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_93708</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631262.1">
        <property type="nucleotide sequence ID" value="XM_040777176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFR9"/>
    <dbReference type="STRING" id="1858805.M5GFR9"/>
    <dbReference type="GeneID" id="63692238"/>
    <dbReference type="HOGENOM" id="CLU_005863_1_0_1"/>
    <dbReference type="OrthoDB" id="3237235at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902929">
        <property type="term" value="C:plasma membrane of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067726" description="SH3 domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="799"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="906"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="877"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="963" mass="98863" checksum="B122AFAB7CC0D23E" modified="2013-05-29" version="1">MFTSSLPFSLVLLILSTSSFAQQQFNNVTLDPAASTLFSTSSGTLSPVGTTEDGGRILAACTLDSTVYVAGSFSQIGGTSAQNVAAFDSSSSSFSALPKGGPNDAVHALYCDSANNLLWLGGNFTLPSPGAAAYAPHNSSWVPAPFVGLSGEVLAITPFADAQSIYFAGSFITAFSSNSTNSTFGNNPNVPYSAGATPYSSSLVPIPLQGAQITAEPATGQTGFSDITNILCPAGADGEGNTWLAQDGSAAQITVRTFRNEGVSGVRLGNTFVQGRGTTAFTVTTIPNNQVLPLSYIDPVTNTTQNCSDSCPLLTNTTIPYQDFIFNQTPALTITGFQLTLNTWAGAGAGLHLLQLLSEGSFASFVPGLDTASCFAPGPTTVTQTGNWQEVNVTTNTAGTVQPILQATLPTNTPPASSPSLDLSVYVSAVGYYTVYFVTPGCTLMEDCDLRTTVQVTISPGNSVAPVTQEIDQRVTSDTITTVYRGPVYPTSPSFTIPVSLRLSGTPAGTGSDGNYDMVADQVQFVLTAAPNGTGESVVGEGVPGYNLTMTSSGIARGFGLFEWPERSAAENATGTLSTGLETSVDQAGAALYAGILGASMNSFSVAAIAQFGASVISALAVGNNGTLYIGGLFTLSTVGASNIVMWNGSDLIPLPSGGLNGPVTALAIDNSAGHLYVGGSFSGPQGSTESGFTGIGLFDIAASKWTSMAGGLNGPVTGLAFSSNQLLVVGNFTALPQNSGIPAAGIASWSLSAASWNPPSGFVVGNLSFISTDGQFMGGRVSMSSISYGSSGHLSEGLVILVCIVIGAGCVLMLFLIGLLIALWLRRSEQAPQALADKDDDDAASSIGQHPSTLLEHVQAATRATIIGEGAFAGGNIRSEGSHEQVADDSMETEEAVGGAGPFADDGRVAHARYSFEASGEGELEIHAGTQVQVLDDRDTSWWLVRDVETGREGIIPASYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG20</accession>
    <name>M5GG20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1748-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_47760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631617.1">
        <property type="nucleotide sequence ID" value="XM_040774780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG20"/>
    <dbReference type="GeneID" id="63689842"/>
    <dbReference type="HOGENOM" id="CLU_151392_1_1_1"/>
    <dbReference type="OMA" id="MIQGTVV"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF3">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="75" mass="8113" checksum="613287316894574A" modified="2013-05-29" version="1">MVIGRLIHYAVDAVLISTVLAGVKRSSGFAPDTLLISDPTARSLVDKYLGVGDSVFDMVQATAVGSTYWKREARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGM6</accession>
    <name>M5GGM6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Oligosaccharyl transferase subunit OST3/OST6 family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_62405</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632647.1">
        <property type="nucleotide sequence ID" value="XM_040775695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGM6"/>
    <dbReference type="STRING" id="1858805.M5GGM6"/>
    <dbReference type="GeneID" id="63690757"/>
    <dbReference type="HOGENOM" id="CLU_052855_1_2_1"/>
    <dbReference type="OMA" id="VLFGMYS"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067841" description="Oligosaccharyl transferase subunit OST3/OST6 family" evidence="10">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35677" checksum="F66C5A8771604392" modified="2013-05-29" version="1">MRLLYGVLLLVASLSAAVAQVTHAELVRLAAANNGVIKLNPVLYDALTAPNRQWSAAIQFTALSPQFKCSPCSDFNPSFKSVAKAWSKVHSAERDQHFFATLDFLEGQDVFKRLGLSSAPVLQFFPALEGPSVRPNPQRLEFSYDFSRHGFDAEELAKDLSNHTPIPIPYTAPFNWQPWFFGFTFLVLSLVAGRFAWIYLREIISNRWLWAAATVGLTLVMTSGYMFVQIRGMPYAQHNSMIAGGFQNQFGIEVNLVAALYGLLGASYLALILLVPRIPSPIRQRASVYLWTGILFVLFSILISFFRIKNGGYPFKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGR3</accession>
    <name>M5GGR3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_112766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632832.1">
        <property type="nucleotide sequence ID" value="XM_040769505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGR3"/>
    <dbReference type="STRING" id="1858805.M5GGR3"/>
    <dbReference type="GeneID" id="63684567"/>
    <dbReference type="HOGENOM" id="CLU_049749_5_0_1"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="50"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="252" mass="28361" checksum="C25C9E17908D166C" modified="2013-05-29" version="1">MAAPAPAPAPTQYDSIARIYTDATESSLHNTYIERPAMRQLIGNVTGLDVLDLGCGTMILGSKLLEEGAASVTGVDGSSEMLHLASQRIKAEWKPRVSLAEHDLNRPLHLPDAKMYDLIVSSLALHYLEDWKPVLGSAHILLKPRGRFILSVHHPFADWVHHPESGSYHSGPTLLHEDWDVGEQGTIRISFYRRSLAEICRAFTDAGWIIQRIEESKPTEESKALFEAERWERVAEKPNFILFVLVKKEQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGV7</accession>
    <name>M5GGV7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19441</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633052.1">
        <property type="nucleotide sequence ID" value="XM_040771511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGV7"/>
    <dbReference type="STRING" id="1858805.M5GGV7"/>
    <dbReference type="GeneID" id="63686573"/>
    <dbReference type="HOGENOM" id="CLU_026673_14_0_1"/>
    <dbReference type="OMA" id="IKGRSEM"/>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080007">
        <property type="term" value="F:S-nitrosoglutathione reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000001">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="35"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="205"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU06158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="381" mass="40733" checksum="920AF2E3D0AE6336" modified="2013-05-29" version="1">MSDTTGKTITCLAAVAWEPGKPVTLETVEVAPPKAHEVRIHILHTGICHTDAYTLSGQDSEGKFPCILGHEGGGIVESVGEGVTDVKPGDHVIPLYTAECRECVYCKSGKSNLCIKVRATQGQGVMPDGTPRFKCKGQDVYHFMGTSTFSQYTVVADVSVVAVNPQAPLDKVCLLGCGITTAWGAVTKLPGVEGSTVGVFGCGCIGLGVLNGARFKKASRIIAIDTNPKKKEWAEKFGATEFVNPTDLPEGKRIQDHLVEITDGGLDFTFDCTGNVNVMRAALEASHRGWGVSTVIGVAAAGKEISTRPFQLVTGRTWRGTAFGGIKGRTELPGLVEDYLAGKMKVDEYVTHRRELRDLAAGFDDMHDGECIRCVVDMTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH40</accession>
    <name>M5GH40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uridine nucleosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_74062</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633467.1">
        <property type="nucleotide sequence ID" value="XM_040776046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH40"/>
    <dbReference type="STRING" id="1858805.M5GH40"/>
    <dbReference type="GeneID" id="63691108"/>
    <dbReference type="HOGENOM" id="CLU_036838_2_0_1"/>
    <dbReference type="OMA" id="WVGVETK"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02651">
        <property type="entry name" value="nuc_hydro_IU_UC_XIUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015910">
        <property type="entry name" value="I/U_nuclsd_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01247">
        <property type="entry name" value="IUNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38096" checksum="BEF07742D503396F" modified="2013-05-29" version="1">MTRTKVWLDCDPGHDDAIALLMCLYLPELELLGVSTVFGNTTATDTYENALRLLHAFAAPEEITVFPGASKPLLRAARIDSEIHGLHGLGGTEGLTPFSDPAVQARAARAGGRNAVQGMEAAFRDVEGKVTLVSTGPMTNSAALFSAFPDLVQKVERVVFMGGGVGLGNRSPVAEYNILCDPEAAQIVFDLPVPKVMVPLNVTHSAIFDEDAVTRLVTHAHATSARIDLNSIPTTPLRHTLYTLIHFFASTYKKVFDFDGPPMHDAVAVTYAAHPELFEATRYRVDVELAGTWTAGETVVDLWDYRGCDESWGAGGKNVLVTEKLDVPKFIDLFLECVDKADYASPLNVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN38</accession>
    <name>M5FN38_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_72823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623668.1">
        <property type="nucleotide sequence ID" value="XM_040775982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN38"/>
    <dbReference type="STRING" id="1858805.M5FN38"/>
    <dbReference type="GeneID" id="63691044"/>
    <dbReference type="HOGENOM" id="CLU_034579_0_0_1"/>
    <dbReference type="OMA" id="MFMGATE"/>
    <dbReference type="OrthoDB" id="4137487at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF2">
        <property type="entry name" value="PROTEIN YTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="2">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="3">
        <location>
            <begin position="111"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="43587" checksum="7B0F2B6CBAC6A3A2" modified="2013-05-29" version="1">MTWLHVAFQAFVWLVVFPAGMVLGMAKSRWHVPMQVAGLALTTAGYVLGHSHGGREFAWSAHVPMATVIIFLLAAQTALGIYLRLHIHEKTLRPWAARAHGILGKFYPVVGWVQTVFGFATLGGYCRGGALGQCLAHYIMGSAFIAYGIILLILLCVGASFIGEKRSQEWFDSWVICLWGVVNSFTEHQGGPWTHKDLQHTMMGVVWWAGGALGIFLSRNNQRSLLPALIILLTGWAFSAHVQALALSTAVHAVFGITLIAAALTRIVEIVFVLRGQPSGTVREGNISPWQWLPPLGLICSGCLFMSATDEELRWADSLGVDHVTYSLILFSAGFVICLHACLLIHLYMYAGQNGDVAREGGVKLDNGNGHAYAPIHAGEAEMFELGGVDEEDAEELPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNF7</accession>
    <name>M5FNF7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-NAD kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_72248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624263.1">
        <property type="nucleotide sequence ID" value="XM_040775963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNF7"/>
    <dbReference type="STRING" id="1858805.M5FNF7"/>
    <dbReference type="GeneID" id="63691025"/>
    <dbReference type="HOGENOM" id="CLU_008831_6_1_1"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000004">
        <property type="entry name" value="NAD kinase 2, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="703"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="740" mass="81042" checksum="A411C7468A451374" modified="2013-05-29" version="1">MHAPFAPGTWKAAAVPSSSASATGSPADEGDDEYEYGEEEEDGTGESLTKQLADTAVGVREMSKQLGRVRVRSNIQNVLIVTKARDNNLVKLTRQLALYLMLKPRENIRGLTVYVDSQLRDSRRFDAAGIERDHPELFAPVQRRRSSSATSLVSLSDGSHSPRSSVMAGSSASDKRKDKDEGQLRYWTSDMCTRSPRLFDFVITLGGDGTVLFTSWLFQRIVPPVLPFALGSLGFLTNFDFAEHEQVMDSVIDSGIRVNLRMRFTCTVYRAIHRDPSACQQPQRAMKRGSTGEIIMKYNEAEAWQALEAGFSAQHPPLGGGQGKDKEITCLATRPVETFEILNDLVVDRGPSPYMSMLELFADDHHLTTVQADGLVIATPTGSTAYSLSAGGSLVHPEIPALLISPICPHTLSFRPMLLPDSMELRICVPYNSRSTAWASFDGRGRVELKQGDHIKVTASRFPFPTVCADKQSTDWFHAISRTLKWNERERQKSFVVVEEALGPQTGKRSGPAKENGQTTRLHLHASSVAVPRTAVVQEKDEEEDDGKFDIDDSSGDKQPEPAASPSPSSVPQTPKTPVEQEALTLTDVGLPDDFPHSKSGIQTPGRYAGPAGPASHPPRSVLLQQRVHGLSPGRQREREAVHQQMDNMRTPRPEDKFVIGTGGAAGGAVPTPPLPVHGPIVPISAMRPTVSMVPAGKRNVRREREREREREREHSAGRRAFAVYGQDESDSGTSGSEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNG0</accession>
    <name>M5FNG0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624278.1">
        <property type="nucleotide sequence ID" value="XM_040774030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNG0"/>
    <dbReference type="STRING" id="1858805.M5FNG0"/>
    <dbReference type="GeneID" id="63689092"/>
    <dbReference type="HOGENOM" id="CLU_1040337_0_0_1"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="2"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="268" mass="29518" checksum="EFFC0D0AC5CEFCFC" modified="2013-05-29" version="1" fragment="single">MSSTKGLVITVTHRLIERGILDLDAPVCKYWPEFAQNGKEHITLKMILNHTSGCSAWPLEANIGIPDMNDWNRMIRALERMAPFWDPGTEVLYAAWTFGFLIGEIIRRATGKTVGTIFHEEIAQPLGLNLWIGLREEKEPRVIPWMPKTLPKLAPGAAVESLEATAMDVDWSNPLIASYLPFDESVLHTFLNSREAHAVEIPSVNRIGDARSLAKLYAHIIGEVEGKTPLLKPDTLKRAIASSIDGIPAAGPLRGVLPPGSLQFGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNL5</accession>
    <name>M5FNL5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nop domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_119316</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP31 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624553.1">
        <property type="nucleotide sequence ID" value="XM_040770766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNL5"/>
    <dbReference type="STRING" id="1858805.M5FNL5"/>
    <dbReference type="GeneID" id="63685828"/>
    <dbReference type="HOGENOM" id="CLU_026337_2_0_1"/>
    <dbReference type="OMA" id="IGNGPMD"/>
    <dbReference type="OrthoDB" id="4771285at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000002">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein Prp31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000003">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027105">
        <property type="entry name" value="Prp31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019175">
        <property type="entry name" value="Prp31_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09785">
        <property type="entry name" value="Prp31_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="224"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="500" mass="54554" checksum="C701874D7445780F" modified="2013-05-29" version="1">MAEGEGDEEDEEDEDMQPAGFDEGDLGTGLVLEGGVKPAAELDSEEVNKMELEGVADVTSVATLEQQPRLKEILQKIEEYSSRPAPSEDVSQLPVHQNPEYQLTVAANNLAVDVDNEILVVHKYIRDNYNPRFPELETLVPDSWQFIKAVRALGNVEDIASVDLAAVLPPAVVMSVRVTYTTTSGKVLAETRWKAVERACDLADRLEGARVKIFNYVKSRMNIIAPNLSAIVGTTTAAKILGVAGGLGSLIKMPACNYHLLGAQKKIAAGFSTATQNRHTGFIFQSEIVQETPPDLRRKAQRTVGAKCALAVRMDLERAYRDGSYGFKVREQVEKHLERLAEPPPAKVVKALPVPTEGRKKKRGGKRARKAKEAYAMTELRKLQNRMVFGQAEEEAGAFDETVGMGMIGASSGRVRASTGEEKSKAKMSRANKLRTQAITNAAKRSMGQASGTATSLVFTPVQGLELINPAIQAQRVKEANQKWFANGTFTFVGQKGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNU9</accession>
    <name>M5FNU9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_91365</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624848.1">
        <property type="nucleotide sequence ID" value="XM_040777006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNU9"/>
    <dbReference type="STRING" id="1858805.M5FNU9"/>
    <dbReference type="GeneID" id="63692068"/>
    <dbReference type="HOGENOM" id="CLU_021364_2_2_1"/>
    <dbReference type="OMA" id="PRSWCQG"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20341">
        <property type="entry name" value="BRcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23134">
        <property type="entry name" value="RING-HC_ITT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000416">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067103" description="RBR-type E3 ubiquitin transferase" evidence="12">
        <location>
            <begin position="31"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="122"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="126"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="421" mass="48436" checksum="D2923BC08712F496" modified="2013-05-29" version="1">MDHTSVAIRLTYLPPLLLTFCLPPLYPVEAGPSQLSLHAMHSWIFPSAQLLIKEALASRWDATLGEGVLWGWAEWIRSGEFLDTIRLREGHIIKLSHPAPELLAPTLQKHNSMLRNSEFTHGTYLCAICMNTQKGTQCLRLARCGHVFCRSCLKDFWGLMIVEGDVSRVTCADPDCVKKHMEVDEEDVRRTCGEDATERWKWLREKKELEKDPTIVFCPLQVCQAPVRKPKVEELPSDQENRWEALRTCSHCGLSFCVYCRRTWHGILTRCVFSQAQAFVPEYRKASKGSHARRAIEQRYGRANVLRLIAQQEEDEKNKEWLKQSTMPCPGCQVYVEKSFGCNHMTCVKCGCHYCFSCGNKVNAKDPYAHFNGGRSKCMLFDAKELREDVPWDPVLEEHQIMPEGPAAQFFGEPNWRRWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNX0</accession>
    <name>M5FNX0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624918.1">
        <property type="nucleotide sequence ID" value="XM_040773740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNX0"/>
    <dbReference type="GeneID" id="63688802"/>
    <dbReference type="HOGENOM" id="CLU_2216093_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11843" checksum="82D0CD8B4A4DFDB8" modified="2013-05-29" version="1" fragment="single">MKLATRMSGISMRINANDKTVDEILQRPPNTRSSSATGFRRNDQIPAIHFPGVGVFSQADIGFYHSGPSRYRQTQVQAQSDCRRPDGEKDDGFPRPSSYITGVPMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPA2</accession>
    <name>M5FPA2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623816.1">
        <property type="nucleotide sequence ID" value="XM_040770852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPA2"/>
    <dbReference type="STRING" id="1858805.M5FPA2"/>
    <dbReference type="GeneID" id="63685914"/>
    <dbReference type="HOGENOM" id="CLU_1468124_0_0_1"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="184" mass="20710" checksum="CCFEDE2E78F616D1" modified="2013-05-29" version="1">MRKLRVLALHGFGQNALRFQKAIGAIAKECAADVDFDSDRFNGIFGFSQGGIVASYLCSFLENRDAHPLFENCNHPPFKFVVLASGLLPIEPSLPPIMIRTPSLHVFGRNDTYIHNSDSHMLAAVFKRPRIEYHDGEHFVPTKLTWRQFFHDWMLAFRPETTVIPEAVADPVARCGSGELLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPL3</accession>
    <name>M5FPL3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_97280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624046.1">
        <property type="nucleotide sequence ID" value="XM_040777438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPL3"/>
    <dbReference type="GeneID" id="63692500"/>
    <dbReference type="HOGENOM" id="CLU_2145774_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12741" checksum="E22C0A4C9485147D" modified="2013-05-29" version="1">MHDVTTEDMASLTTSPSSCQCIRLQYRTYVGWRDPFLLDILCKLLCSAAALDAVDWLAVVSFQGSRPRREEVCRTRNPPPLHHLLLSSPSGGNKYPREIHSWWHCVANDRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR60</accession>
    <name>M5FR60_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_119474</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624262.1">
        <property type="nucleotide sequence ID" value="XM_040770797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR60"/>
    <dbReference type="STRING" id="1858805.M5FR60"/>
    <dbReference type="GeneID" id="63685859"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OMA" id="YCISIGA"/>
    <dbReference type="OrthoDB" id="5141738at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF75">
        <property type="entry name" value="GALACTOSE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067214" evidence="12">
        <location>
            <begin position="19"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="13">
        <location>
            <begin position="10"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="485"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="520" mass="56284" checksum="5FCD9E3F303EC9C0" modified="2013-05-29" version="1">MPLSPFSVLLALLASTGGFIFGYDTGQISNILLMPDFLLRFAVCTGTSDPATQCAFYPAIEGLIVALLSVGTAIGALGGAPVADGLGRRKAMSVECAVFAAGVIIQVTAFSAWYQLAIGRFVSGVGVGALSAAVPMYQAETAPSEVRGTLTGTYQLFITFGILVAYLVSLGTRALNDSASWRIVIALGIIWALILGVGILFMPESPRWLIQRGRMEEALASIRRTHGDTPEVEADFEEMRQAVQAEQHTGSVSWSECFSRRNKTLYRTLLGMSLQSLQQLTGANYFFYYGATIMRAVGMQDSFITQIIFGAINFGCTFLGLYVMERFGRRWPLIIGGAWQSAWLFVFAAAGTAASPDLTAHPTLGKLMIVSACLFILGYASTWAPGVWILIGETFPTRTRAKQGALSTASNWIWNFLLAFFTPFVTGAIGYKFGFVFASCNLLGALLVAAALYESGGLSLEKVDRMYNDRQVKAWTSGRRARILEKQEGEGLGQEKGKGRMSAESGDSRESTLVERVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR76</accession>
    <name>M5FR76_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624297.1">
        <property type="nucleotide sequence ID" value="XM_040771387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR76"/>
    <dbReference type="GeneID" id="63686449"/>
    <dbReference type="HOGENOM" id="CLU_688917_0_0_1"/>
    <dbReference type="OrthoDB" id="3361358at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="400" mass="42336" checksum="CFC2EAF61E92AF39" modified="2013-05-29" version="1">MWMCNHAGASKGPVPSKCGGALPYVAFMSVVHTSNMGPTVTLPMSQGHGQPTTNISRRAAARHRPVSSRVHARSQSSTKLASALAVAQGHRDVTSLTEEKSKRRIKSVEDVASLRPHSSTLSMGGPKTSSRLSTKRASERQSAVKDTVTVTGGVEEEEWTSESGASSPTQATAAVKADEDEEGDYDGPEIRIGPHAHAAPSMRVGYGGISVDDNRSSTPTLHRTLSDPNNLTIQTDFPPLSTSGPSSSKALYHAPRSPHTPSRLRPMSLIRPPSFASAVVTAPTVLDSPASDMPDSPKHDSSAREAAPSIAPSIPSIVPSRVRTISAMSGASGAASRAMDALTRANANPFLTSHFPHLSTQNDVHHLLPPKFVASHMAIKRYWTPVDDAVGRLRVVLKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRJ8</accession>
    <name>M5FRJ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_71936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624517.1">
        <property type="nucleotide sequence ID" value="XM_040775956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRJ8"/>
    <dbReference type="STRING" id="1858805.M5FRJ8"/>
    <dbReference type="GeneID" id="63691018"/>
    <dbReference type="HOGENOM" id="CLU_005391_3_1_1"/>
    <dbReference type="OMA" id="PLVAYWF"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="39"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="496" mass="54827" checksum="E1A4E8CA1F5E5C7E" modified="2013-05-29" version="1">MASAGTNGTNGVSGHAPLPAYKETPIDEIPQIHADLVKSFRTAIMWPLAKRKEQLAAMANMMKENADAWSRAIYADLGKPELQAQLFEIAISNQAVNAIHELEEWTAPIKPDVHERHSEWQPTVYKIPFGVVLIISPWNYPLTLTMQPLVAALAAGNCVVLKPSELAPNVSALMAELVPKYFDPRVVRLVNGGVKETTRLLELKWDRIFYTGNGTVGRIIAQAAAKHLTPVTLELGGKSPVVIDPEGLDFTLVAKRILHGKLANAGQTCVAPDYILCPEASQKPLMQAMTAAMSEFFEETGGKALNNRHYGRIVNKRHFKRIKNLVDKSKGEVVFGEKQTDPERYAMEPLVIKTTGDDDLMGEEIFGPVFPLITIKDVDDAINFIEDRDHPLSLYVFTKSEETKQKFVSRTRSGGIVFNDTMEQLAVGLPFGGIGESGMGYTVGRAGFESMMHLRASVDIPYEHEEAVSLRYPPYTQEKVDIARMIAQPHVPEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRU9</accession>
    <name>M5FRU9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_71440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624677.1">
        <property type="nucleotide sequence ID" value="XM_040775943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRU9"/>
    <dbReference type="STRING" id="1858805.M5FRU9"/>
    <dbReference type="GeneID" id="63691005"/>
    <dbReference type="HOGENOM" id="CLU_003016_7_4_1"/>
    <dbReference type="OMA" id="ITKAQPV"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="3">
        <location>
            <begin position="128"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="674" mass="77377" checksum="F44E5BEC83BCAAF9" modified="2013-05-29" version="1">MSASYLHTSYNLYVDPDAYTFEPIVAGASEPNETLVIDRRTESIVLNPARRHTPVAHERVIRVYGILGILSLTTADFLIVITNRARHGRLIGSEIYLATDFKVLPIPSTANSAQLLDHPVEKRLLTLVKNHLDSGKFWFSYGWDLTRRLQSQWGDVKVEGEGLWRKCDERFWWNRYLSERFIEVTEQGQDLSRFILPVVYGSFDIRHCVINRRPFLFCLISRRSRYRTGTRYFARGIDATGHVANFVETEQLVLLDPEGHSLGGGRIEGRTRLSFVQMRGSTPIFWAEVNNLRYKPDVQIMEVPETTGALRMHLEELNKLYGTVYLVNLVNQTGREKHVKDAYEKYVLEADMPTVKYEYFDFHHECRHMRWDRIQLLIDRLEPALKSEGYFRQELGQPQPIHMQTAVVRSNCMDCLDRTNVVQSALAKWSLLQQLRVTGILGKDERLEDHMDFMNIFREVWADHGDAVAFAYAGTGALKSDFTRTGKRTREGAINDFMNGASRYFKNQFLDGARQDAYDLFTGAWRARRGATVAGWEQRSVLVRSMPYVLLFALVMLAAGALLPRSTSTLPILPFNIIFTLLALLSLYFIQAHGVSYVSWPQLNPPIDMLTYSGPGFREPQHGRGDLGVAFPLLGLARPAKGRVMNEKKQERRRRLNSAVRVEEMEMGPKKRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS08</accession>
    <name>M5FS08_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_57745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625456.1">
        <property type="nucleotide sequence ID" value="XM_040775465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS08"/>
    <dbReference type="STRING" id="1858805.M5FS08"/>
    <dbReference type="GeneID" id="63690527"/>
    <dbReference type="HOGENOM" id="CLU_037990_6_2_1"/>
    <dbReference type="OMA" id="NQIHRYD"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="29097" checksum="08F08661E63C7260" modified="2013-05-29" version="1">MWLPLFLDPLPQLLYCIKLGLPPVLRALYSNPWLIFYPSKLQKIFMAGFWVVFGPGLDEGAAPAKQRLITPFAKGVVLEIGAGHGHSLRYFDREKVEKYFALEPNEEMYPALRKSIADAGLSEEDGTAIILPFGAHEVDKILAAVGENQVDTLVSFLTLCSVPNSKEVIPKLCLAVLKRPGGTFLMYEHGLSPVWSSRIYQRFWSPIWSLTWNGCRLDRNTVKWVEQVPWAEKEVGKEDMPDWHLWYRTMGRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS71</accession>
    <name>M5FS71_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625546.1">
        <property type="nucleotide sequence ID" value="XM_040773611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS71"/>
    <dbReference type="STRING" id="1858805.M5FS71"/>
    <dbReference type="GeneID" id="63688673"/>
    <dbReference type="HOGENOM" id="CLU_708949_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="390" mass="41302" checksum="9F4EC58BD48619DB" modified="2013-05-29" version="1" fragment="single">MSSSSVTSPREKEYFSSALSREEKDDEQETEDGEGEEEEGGGKMNLQQQLKAAIAADPSLSLSPPPATLAPSSVHRATSRSPNRSPNNINVQSSIASLVVPSDPVVDVDERRLSGVGTYDVGLGLLSSDAMSDEESEDEDEDLRVRSPVPAAAGKEKSKAKPQETGEEKPRPPLGLGITVPPSTSSTSNPAHLSLFAAATQAQPSVPLSPFPLPNSPSSAKEKEKDRPMRDQVLSPPPPAYSPQVQGSGLRQGAQEQFSQQMMHPAPRAVPRALNLGPAHQQPPQQPQQQRQPPPPQIRQAHPTPILRSPQPYPAHPQPGSGSPYPTPPPAAVSRFPPSPHSQSSMCEPLLPPHTPGTPGAASSFSPHPLPPSSPIVPRFAAPQSKRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSB3</accession>
    <name>M5FSB3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_38038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627183.1">
        <property type="nucleotide sequence ID" value="XM_040774438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSB3"/>
    <dbReference type="STRING" id="1858805.M5FSB3"/>
    <dbReference type="GeneID" id="63689500"/>
    <dbReference type="HOGENOM" id="CLU_001324_3_5_1"/>
    <dbReference type="OrthoDB" id="3366231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="93" mass="10442" checksum="991277DD56717016" modified="2013-05-29" version="1" fragment="single">WASVEQDHLQWIEHNQKTICAEPYNGLVDAAARADNAEPGQHDLAQIGTHIILPATFVSSAWYMYQLYQDSIAIVCWAGQPDIFLTLTAHPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSF3</accession>
    <name>M5FSF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_96725</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625007.1">
        <property type="nucleotide sequence ID" value="XM_040777397.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FSF3"/>
    <dbReference type="GeneID" id="63692459"/>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OMA" id="QDYWLRW"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000479">
        <property type="entry name" value="Multidrug resistance protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001370">
        <property type="entry name" value="p-GlycoProtein related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="821"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="868"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="939"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="968"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1050"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1085"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="165"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="497"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="825"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="1146"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJT98109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1393" mass="150655" checksum="23D13297A45471CD" modified="2013-05-29" version="1">MEQTNATPKEAPVEAAIDPPQVSTIDVDSSVIGATSAPITMDQPPSVVQGSKDDMVKDARDLSTVTIQSDSMVEAAQTVPVNIKDASARVHDDSGDAISEKGPPAGEPEKGHGLFRRRKQKPVKEDILAKEEATAIKSVVDESGGPVSFTSVFRFSTRRELFLNFIGLLCACAAGSAQPLMSLMFGKLTQGFVVLGAALQGGGTPDFSSIAGDFLTTARQDAMYIAIIAGGMYVTTHIYMLIWTYTGDLAAKRVPYLQTVLRHDIAFFDTLGAGEVATRIQANTQLIQSGIGEKVPIIMTYLSGFVAGYIIAYIRSWRLALALTSILPCISISVTIVAYFVGKALKTNQDAIAASGSLAEEVISTIRTTKAFGIQDTLSKLYKMHVDIAYHAQMTNMISQSILMWVFFFVLWSAYALAFYYGTTLVLDGIGDVGVIVNVFMAIVLGSFSLAQMAPEMQSLAAARTAASKIWATIDRVPSIDSLSPAGLKPATCEGRITFENVRFRYSSRPEVEILKGISIDFEPGKTAALVGASGSGKSTIVSLVERFYDPIEGSVKVDGVDVKDLNIQWLRTRSGSSHRILHTASLVPPYEHASPDEKFVLIKDAAIEANADNFIRSLPDGYDTNVGQAGLLMSGGQKQRIAIARAIVSNPRILLLDEATSALDTQSEGVVQQALDKASRGRTTITIAHRLTTIKDADQIYVMDQGTVIEHGTHDELVAHDGPYHRLVNAQKLREESHPETAEVPLVGVETRSDGTDDAESVVSVKPEIEIRPASGLARVLTSRSVASVNTNKDVEPLVDQDYSMLYLFYRMSKLCKESLPYYALGSCAAMATGMVYPVFGIVYGGAIEGFQSTGQDLRNAGNHNALLFFIIAIVASVWLMFQSLFFGKAAALLTSKIRNSSFTALLRQDAAWYDEERHSTGVLTSNLSENPQKVNGLGGATLGAIIQSLTTLIGGAIVALCFGWKIALVGIACIPLTLMAGIVRLQVVVLKDKRNVLAYEQSSKLACEVAGAIRTVASLKREQTACAEYSKSLEEPLRHSQRTAIYSTGLYAFSQAASFGTIALLFWYGSGLLTNEGYSVKNFFITMMSVVFGSMTAGNVFALLPDISLAKRGAASTVALLDSDPIITSASGAQKVPEDLKGQLEFREVHFRYPTRPKIPVLRGVNLTIKPGESVAICGASGCGKSTMIQLFERFYDPLFGDVTIDGISLRKLDLADYRKHIAIVSQEPTLYAGSIRFNILLGATKPPEEVTQAELDKVCQDANIFDFIQSLPHGFETQVGNKGTALSGGQKQRIAIARALIRDPKVLLLDEATSALDSQSERVVQEALDKASRGRTTIAIAHRLSTIQNCDRIYFMREGLVAEQGTHDELLEIRGGYYDMVQLQGFNHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSM8</accession>
    <name>M5FSM8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_83945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625102.1">
        <property type="nucleotide sequence ID" value="XM_040776653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSM8"/>
    <dbReference type="STRING" id="1858805.M5FSM8"/>
    <dbReference type="GeneID" id="63691715"/>
    <dbReference type="HOGENOM" id="CLU_509993_0_0_1"/>
    <dbReference type="OMA" id="VNWERIR"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="267"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="534" mass="60616" checksum="15645891B1F54B81" modified="2013-05-29" version="1">MLKRASPVFASSLSELTAEIPLIHIDAEGRTIDMLLQYIYPDCRPEVGSDFDAFLAVLQLAVVYQVGHVMQILRKMLVTPEMLTQFPIRIYAAATRWRFTAEAEIAAEATGRLDLARASEKEVGNISATDLVKLMGRHVRRKSDILEALKGWKSSLCKTCQSMPGDSWSMRYYVRAVDEVKKHPATDVIFSEEFINQETGKSNCPECDNYFVLSQRLKDLKQAAAHSMRRQSPSYSRKSVQSTVSTIAPITPIPSTPQLENIFSEGDCILRSIDSQDIRVYRRILIEASMFWKHLFSLPQSQPDVDPADPESAVPIVDCTERGRTLKLLLQLIYPVPKPKFRTFAQIEPVLEAAHKFEMDAALQHLAGILREAHFIQLDPVRVYALACRYDLPELARLSSSFTLRSDLEQTAEESVFGLSAISFLRLLQFRDTRAAQITAILTERAPPSPCEQCKIAWASNWLRLALEEVCRRPVSDTIFGLSFVTKSFDVEQVRRSFDRIGYHQCNNIFNIADHDWLQELKKKIDMLPESLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSN8</accession>
    <name>M5FSN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24699</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625127.1">
        <property type="nucleotide sequence ID" value="XM_040773800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSN8"/>
    <dbReference type="STRING" id="1858805.M5FSN8"/>
    <dbReference type="GeneID" id="63688862"/>
    <dbReference type="HOGENOM" id="CLU_037637_1_0_1"/>
    <dbReference type="OMA" id="RFVVMTH"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000001">
        <property type="entry name" value="Probable Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.30:FF:000003">
        <property type="entry name" value="Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="151"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="77"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="33838" checksum="C110864156CEBD86" modified="2013-05-29" version="1">MSSDRIEFKRLVKDVVESSKGPKHSDTVGLLQKLRGHGVTEDLLKETKAGLAVGKLRSHANAQVAETAKEVVRRWKAEVEGQKSEKKAGSSSPSGGAKKVNPKPIQTSVPGSTSSKSPAPATAGPHTPLSPSLVRTTATDGVKLNDSGDEKRDTCMRLLYDALASDSTAPSDQIAKIARKIEEQVLSLNKNNSGNPYRTKIRSLYLNLKEKSNPGLREAVVSGELSVPRLCTMSVQEMASEERQAESKRIEEQNLFKAKGAEEAGAETDAFKCFRCGLRKTRYTQAQTRSADEPMTTFVTCVNCGNRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FST9</accession>
    <name>M5FST9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_23016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627468.1">
        <property type="nucleotide sequence ID" value="XM_040773054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FST9"/>
    <dbReference type="STRING" id="1858805.M5FST9"/>
    <dbReference type="GeneID" id="63688116"/>
    <dbReference type="HOGENOM" id="CLU_027154_0_1_1"/>
    <dbReference type="OMA" id="NIGMVGH"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000011">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000065">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="31"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="459" mass="50027" checksum="DC8D61DBB415C797" modified="2013-05-29" version="1">MAESKANGLPEQVEIPVEEMTPLTPGIITRQATINIGTIGHVAHGKSTVVKAISGVLTVRFKNELERNITIKLGYANAKIYKCENPACPRPGCYKSYRSDKEEHPPCERPGCNSRMNLVRHISFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAVEIMKLEHIIILQNKVDLIREQQALEHHKSIVDFVKGTVAESSPIVPISAQLKYNIDAVNEYIVKRIPIPVRDFTSDPRLIVIRSFDVNKPGAEVDELKGGVAGGSILAGVLRVGQEIEVRPGIVTKDNDGRVHCRPIMSRIVSLFAEHNDLKFAVPGGLIGVGTRIDPTLCRADRLVGQVLGAVGKLPAIYTELEISLFLLRRLLGVKSDDKKQTKVQKLTKGEVLMVNIGSTSTGGRVMSVKADLAKIVLTSPACTEIGEKVALSRRIEKHWRLVGWGSVRRGVTLDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT52</accession>
    <name>M5FT52_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT52"/>
    <dbReference type="GeneID" id="63688796"/>
    <dbReference type="HOGENOM" id="CLU_1304819_0_0_1"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="1">
        <location>
            <begin position="16"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="28468" checksum="AA07FF5F608FCCA3" modified="2013-05-29" version="1">MQLGPYQCILVSSDIALPEYGVEVDEASNEAVCWIPSDEGSAFRVECAFGGMVHETDGIRMELYADGEMLDTRIAVDTNETVMNGLRTNSWNVLPYLFKPAVKPTEDFDEDEMAVEELDDIQTWRKRGVITLRMTRVDVLYLQPLKDHEPSSQMPAQERLKTVLVGEKGHSPTKKSSRKTVSWAWGEDGDRPCATFHFKHRPQEWLQAYGFAPRDIVSDLDFNSFNLSGEADYVTDMKRMTLHHRSRVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT59</accession>
    <name>M5FT59_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
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        <property type="protein sequence ID" value="EJU00771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT59"/>
    <dbReference type="STRING" id="1858805.M5FT59"/>
    <dbReference type="GeneID" id="63688162"/>
    <dbReference type="HOGENOM" id="CLU_009834_22_0_1"/>
    <dbReference type="OMA" id="EVFTMEY"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
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        <property type="entry name" value="ECH_dom"/>
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        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
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        <property type="entry name" value="HIBYL-CoA-H"/>
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        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="466" mass="51638" checksum="969F0558E6A7DE63" modified="2013-05-29" version="1">MAAAMTPSKFDALQEVPVLFEEHQFTRTYVMNRPKALNALNEEMIDLMRPKLDLWNYTPGCKIIIGTGKGRAFCAGGDVRAVVKHASEGDASTRAKAAEYFRKEFELDYLLANLRKPYVAVLDGITMGGGLGLSVHAPFRVATENAQFAMPETKIGYAPDVGATYFLPKLDGCIGAYLALTGNTIKGREVYELGLATHFVPSERIPKLLERLAQLNPPDFDAVNAAIEEYAADDYSALSTDLVGEKRRMLDKVFGQETVELIVEELRGLRKREDSIAAWAVTTLEELELRSPTALKVALEAYRAGKGGLTLREALLVELRFATAFCNGASPDFITGVKAVLEDKIKGRPTWEPSTLKEVTADDIWTRFFSPTSPFTKTMPKMDLDFVEPLNPPRDVMHFALPSEKEIGRVIRGEEKDSGAFAVTAEDVVRWFADKSPGKPGVAAKVREVLERKARTKKDGYLQWIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTR0</accession>
    <name>M5FTR0_DACPD</name>
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        <recommendedName>
            <fullName evidence="4">Telomere-associated protein Rif1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040769109.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FTR0"/>
    <dbReference type="GeneID" id="63684171"/>
    <dbReference type="HOGENOM" id="CLU_242891_0_0_1"/>
    <dbReference type="OrthoDB" id="2591260at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="837"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1302"/>
            <end position="1355"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1438"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1564"/>
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        </location>
    </feature>
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        <location>
            <begin position="36"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
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        </location>
    </feature>
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        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1256"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1302"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1400"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1510"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1528"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1564"/>
            <end position="1573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1639" mass="178783" checksum="85F06C2D36268CBA" modified="2013-05-29" version="1">MSIDTPTALAKENFAPQRVEFLPIPQFHSPRALSRVRSSPSTQQPKGILKPSRSTLPDLPSSSPVSMDQVVVGDVDYLLSPLQCILRSITQDTQDTQDSDSDAPTPADLTEAYTLLLSRLKHARDLLPSALEPLRTHSTALLIALQRDIAVVLQSPYDPSSTRGSDDPSSEPSSTPAKKRGVSESEILHARALLHLSHAALKLSAVLFLQPGVHALFTTQEQQDLVRSVLSLPEAGALPTPNGRKTNQVALWALGNLRLPDSAVFPHREALARVLECGLRGELGARATSVGGSGEAVRTQAYDTLTTLLTHYPSLLPSFTPLLDLLLPALLLPKREKPAQALLAFSLSLKKYRAHCTSLHASDLKHRETVESHLLTWLRSTRHSPSPSGTTSQKTVDLLEHSLRASLLSSEQTLVLPLIAALIHLSGPQVLASSALKALMTVLQAALKVKPLAPQWARCWAVLIWGVGEGEVRGLWAPSSPAISFSTSTPVAPAQAGAKLPPREKIEKMVLQALPALLKASARAEAAEVWQALVWAGVGVGGVGGGKGRWRDVAGLVQKGGVGVLEGVLGPAWGEEEEGEEGEELQGDPDGEEEPAQPNDKPHHPSKPSHPLESLLSEELLTPPSPTKSPPYTPFQPPPWWPGLQVADVYPLADLWFSGLSAPIPPEERDVSARRVLPLLAHKPGGRQLMFVRILNSSLQELAAKTEEEWRARATDFLGFILPQRMGKCFLPNPGRELVSLLLQQVIPDLPIWKLPVLVYLLTSPALGWKTDTLELIVHSVAGRIPDARGRPGSGEWKACIPPVLQLWIPRLERGINVQDASVIRILLSWIRESNDQNQDQNQNQDQDQNQNQNQNQNQEQWRRILRAVGPLALPNGLALQDMPFVLQCERGDTLKGPLLDMLAVVMRDVYDSDDEKKFDAGMEVLSSLLGAVQRLAASGEKADMDMETDTDTDTDTVYVVCRVYAAVGSWICDKDTLFEDEQYNTLSAALYTACLDLLTPFPQGKVDQSTLDQLAPFLASAFYRMPDPGIAPQRFASFWRATFHGHEFRWPEELKPALRWFAEHDTAFAPGLELDLTQTQDTAASSIPMSVLSDSEPERAQQRLRLTMDNSGSELMSGILSMGEQRGKKVGFGSSSYIDPATLGSGPKTGLSPASRERGSLVSTKPVVRFELSALAAAEGDEPPLRETQEASSDSAEEIPQPQGTSEVVSTATVMRAFDAPLIPPAMMDRTERVPPPTPSMLVLTPSVLDPAPTPSSEPASVDTLTRTDTSLEISHVSETQLPDRRIETDDSVTDIQGAQVTRLLSTPRSNNKPAPSPASPSEEEDDEDEAVIEFSLSQELEDPMKVPELDDEKELDDVFLVPPLSLGKRKRTLSEHTMDARKKRKTPSSVSRLATKGDTSLSDVRSSTSSLSKTSPEVSIQDVEDTFIRDAGNVISASQPTISSSPEVIVARSLSQPPARPAGETRKRKRVFLESVEIPIISKRRRLTSSESTSKDSGRRRRRDDESFQASGTPSTPSHMTQSQRSEASSPASPSLAAGGSQFWRGVRYAFSRVAGQKTEDLSQQFVGSSQQDEDQIVHPPRGSSVAEERVKTLRELLKGLKEDVKHVDMKLIDEVQISLIDALGYVSKRRKADRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTW2</accession>
    <name>M5FTW2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626476.1">
        <property type="nucleotide sequence ID" value="XM_040768923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTW2"/>
    <dbReference type="GeneID" id="63683985"/>
    <dbReference type="HOGENOM" id="CLU_852640_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="37028" checksum="2F84D129C30BBC15" modified="2013-05-29" version="1">MVRLTTKQLWSPVDVEETEFGFQFPVDTPALIEVFMLANALEVAELRFPMPPACVAALLESSSSTLVHLEIETGFERFTSRNISMLRCLSRLRELKITFNWDDGNDSNAEPIPPVFLPQVKILNIGFFGGWHTCAHVLGALRIPLLLSVTLRFYLRDRVEIPVGVVHGFLNRHSATIQEFTITPSSTLQPSFISLLKSLRLLSLPWISTAPDRSILQVLPPTLAELRLDIHPPEDTFAEEQNAFFEELLRASLPSLKTIHGWSGWNVLLWKKLEDNPDKQEPTTRKLFEIARAFRLKGIELLDSSGETYSDATRDTDTDRAPRHQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU25</accession>
    <name>M5FU25_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_118291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625892.1">
        <property type="nucleotide sequence ID" value="XM_040770557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU25"/>
    <dbReference type="STRING" id="1858805.M5FU25"/>
    <dbReference type="GeneID" id="63685619"/>
    <dbReference type="HOGENOM" id="CLU_016305_1_0_1"/>
    <dbReference type="OMA" id="VCNLMTC"/>
    <dbReference type="OrthoDB" id="3366777at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024660">
        <property type="entry name" value="UCS_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11701">
        <property type="entry name" value="UNC45-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="UNC-45/Cro1/She4 central" evidence="6">
        <location>
            <begin position="16"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="4">
        <location>
            <begin position="331"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="685" mass="73284" checksum="70E1AF4FF541A956" modified="2013-05-29" version="1">MSIALKTSTAIIISEEEIDALFAFLSPSQPKDVRTQGTVTFATYVSHTRQGKSPEAGTAEIERTLTVPLEARISSTDVSKALEGLALLTTLFTVDPLSGTALLANEGLQSHLTDLPDIFPGNNEIEGSLAGLLSQASDVKACRALVSKDWGAFLRRAANRGGEGTKTRAMLALLKLSHGGEGGGDVNEKGVDVQQEEEIVLARSLAQELVCEVEKTDEPLDTVEALAHLSMTPAVREDLSRNSPFLRSLFVLAQWKKRATLPLLYGVSVIICNIVTYRPKLAGDEAQLDRLRRMAKGGMVHGSHKLRDEPIPKLEMDEAVQERCRRLLKAGVVPVLVALTRSGGDSAGVRASVGGSFLSLAEDKENRGLIIQAGGAKALQTIIQTMLAEVSKAPSSSLDPPHTDAVLLSPIQALAKLAITSSPLLLFGPTPASSIDAIRPFCTMLSNSQSSLLQQFEALMALTNLASLGPEISNRISGQPGSLSLLDQLMLHDNTLLRRASVELVCNLVSYQAIFQRYTTDPGSKGRLHVLLALSDVDDKPTRLAASGALAMLTDSPEACNALLSLPKGAQNTFTIVAQLIDPGLVPKIVELDSSEPLSESDMSDNRSNEAPDPGLQHRGTLLLRNLLLNTKPQADARVAEKAGAVLALVTMLKTFQRKEGCEGMVTAAVESLTWFVRNGVRIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU26</accession>
    <name>M5FU26_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulator of G protein signaling</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_55403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
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                <person name="Martin F."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
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        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT99673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="383" mass="43940" checksum="03000778D7E12EBB" modified="2013-05-29" version="1">MPIDRLPSFQEVLARKTRPPVDLFMFYLFLQREQAEDVLDFWLDVQQHENLCRAYFRDVRKSGKSIKEDWPQYWDYARSRGSIYGNVVGVHSGKRSTASTANITDAEKAGIVSGSRAASPRPATPHGPNPFDSQHLGEDAPHRSTTPFSFRRASAMNKRASRAPTVIPRDTAITRMDLISSAERIYARYLMPGTEKEIYLPSTLRVHSFPLNSRELPRPTSPDYDIESSALAQVPDMFHIQKEYVFRTMEQDAFPRFLRAKAFANLTPVSAFVRLCGGMFCLWAALSTAYTLIFLDIQPKSRRFFLFIPFAFAALFLISYQYELDPILVFFGQSETTPFRLIRIREPYVKKLLFGRALWVSLTIVVIFTVLTIIFWAVPGHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU87</accession>
    <name>M5FU87_DACPD</name>
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        <submittedName>
            <fullName evidence="8">MFS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_107828</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="entry name" value="MFS_dom"/>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067259" evidence="6">
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            <begin position="29"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="74"/>
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        </location>
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    </feature>
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        </location>
    </feature>
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    </feature>
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    </feature>
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        </location>
    </feature>
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            <begin position="305"/>
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            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="43337" checksum="BC9FCE275559CACF" modified="2013-05-29" version="1">MAQIFGRQSSVLTFIFLFAVGSAVSGSAQNMTAMIAGRTVQGLGAGGILSMSEIVVSDLVPLRERGMYQGIINSVWALAGVTGPPIAGGFAGAGQWRWLFYINLPLCGVAFGLTFFFLKLKRPPGSVREKLGRIDWIGNGIIIIASTIVTLALVEGGIIHPWNSFQILVPLVIGIVGIGLFLVYENFWVIGEPMVPFDILSNRTSLSGYAAKSQHPALSVSFHVSPLLITAITVSATNHYVTQNVTSWALIMIGAGLMTTFTKDSSTATWVGYQIITAIGIGGLYAATTFPVLAPLSITKNAHALAFYIFLRTFAQTFGVSIGATVLQNELIRNLPSAFFSLFPADANIAYAAILQIPSLPEPLQDEVRVAFATSLSTLWKVTLGLAGGGADNDILHETDCFASGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUF1</accession>
    <name>M5FUF1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626751.1">
        <property type="nucleotide sequence ID" value="XM_040768856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUF1"/>
    <dbReference type="STRING" id="1858805.M5FUF1"/>
    <dbReference type="GeneID" id="63683918"/>
    <dbReference type="HOGENOM" id="CLU_133353_0_0_1"/>
    <dbReference type="OMA" id="ARINHDH"/>
    <dbReference type="OrthoDB" id="2562934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="14668" checksum="E597AC534A01DE79" modified="2013-05-29" version="1">MTSIAPLDVWVDNLFGEIWFQPDDEKAFAAFEAALSEDIRIEFVNGAVLPRSVYLGFVKSYRKESFGTDLGNPSLSMNINDADKQTGTVAQFGKFSTKNKATGKETLSTAATIIEVEFRDGKRVMTSLTEVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUW5</accession>
    <name>M5FUW5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_56063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626222.1">
        <property type="nucleotide sequence ID" value="XM_040775353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUW5"/>
    <dbReference type="STRING" id="1858805.M5FUW5"/>
    <dbReference type="GeneID" id="63690415"/>
    <dbReference type="HOGENOM" id="CLU_014798_3_1_1"/>
    <dbReference type="OMA" id="SGIWRQI"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="7">
        <location>
            <begin position="179"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="52382" checksum="D97EFF0CA9E1981B" modified="2013-05-29" version="1">MKSWSQAPPLKPPLWSTAAGDPTEGLSLEQLRQWYEERAESRLKGQYESTVRGIVELLEDASSAPLRLTALRITAPHTSQAFLDNLLSPYLGSRKTSDSPYSTVRSVLKQTRDVTQALAATSIFTSLQPTLVRSLSPLAETGDVELLVVAKGRSRRFLKGETNVGNSEASGSISGKLFNTLGCGDSLSVVVSTGTRTRRSTEISFDQPLPGWELNTRGEGGLWEYERDWTGWAGCWERQRGAKAGISTRTLLGHHTLAYTLVSRQIHTLAPTASLSTRLAAGTNIKSSFTHTLQNSAPNWSYRLAQEVAGLAGDAKFVRLEADFSRAIPLTTNLSTSFTARTAFIRPLSESPVPLSDRAFLGGPTSVRMFRMNNMGPHDGLDATGGELAASAGLSLLGNFPGRALFWPLQWQLFVNSGTLGRLLPGDDLATAVRTTLSRPSVSVGLGLVGRMDPIRVEFNLGVPLAAAKGEGLARGWSVGIGLEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW33</accession>
    <name>M5FW33_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_80789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627471.1">
        <property type="nucleotide sequence ID" value="XM_040776471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW33"/>
    <dbReference type="STRING" id="1858805.M5FW33"/>
    <dbReference type="GeneID" id="63691533"/>
    <dbReference type="HOGENOM" id="CLU_006044_0_0_1"/>
    <dbReference type="OMA" id="LKYYHNC"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="887"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="887"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="920" mass="101167" checksum="F5D90B37823011C7" modified="2013-05-29" version="1">MASPLRVVSPAAVNGADADLDNEAPLTIRSSDLIASLDEYDGDVVGWINDLLDGPAQADGAQKASPLPLSEVDKRVNQLSRRLEITSQDTAVQLERSIDDITRAVPRLTYDLQFMRESAISLRLSLETLQTRSNLQIAGTQTEETTKALEVLQYLDTVKTRMEASLEVLREAESWSTLESEVTALIAEQQYDRASDRLAEANKSMPLFQNTPEYESRRALMVSLQNQLEASLSSALVAAINSRDTHACKTFYSIFTRIQRESEFRNYYYGSRRSNLVSMWQRTPLSDCAEETVVLDAAGLDITPQQTAAPIKFSQFLSRFFTEFLIILNEERTYIPAIFPDPQYTLSAFIQSLFDALNPSLPQRLSAISEFYGAKALPELIETFRSTESLAVEIEKIMEKVGNSAFFAGTGDEHHRPPLSGAQKRSSKRMSISRRMGPGRASISLLPGQIPSSIAPWEQSLFEPFTEFQNEYGTLERAFLENNYRAASKRARAAATEGDKPVDMARLVRAQSAEVFSLAEDAMSRCMILTHGYGGAALVTVLDYLFGLFLDGCRSNVTALRKPPTGVPTPQLGTEPPDIDYTTEDWNVFQLGLHLLETCRAIKERLNVLENRLRNSMGQISTALRLARVDPASHPLPGTTSGEALILAQSGLNSLSLQGLLDLLEKPAASRPHVLDGANSAIVALTKSCQTLLQNIILLPLHAHLVGYPFLPVWAATKDQRNKGAFDLNIPTFSLSPTPIIARVAEGLLNLPRLFEVYADDDALAFSIETLPFVDAESLNALGQDDQIGEPLSRVPSHLSGTAPPSEAPTQTQAPIVLSAEIVSSTWLSSLALSLVAHLTADILPTIVLLSSAGAAQLASDLSYLSNIVRALNVEWDDLERWKELSELSDDEGKERLGLAPLEEQDAPMKSIAKMRRWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW40</accession>
    <name>M5FW40_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDM12</name>
        <name evidence="12" type="ORF">DACRYDRAFT_81473</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW40"/>
    <dbReference type="STRING" id="1858805.M5FW40"/>
    <dbReference type="HOGENOM" id="CLU_026794_1_0_1"/>
    <dbReference type="OMA" id="AAWPSWI"/>
    <dbReference type="OrthoDB" id="3356905at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="282" mass="31834" checksum="9B03B50B6B8E1325" modified="2013-05-29" version="1">MSVDLDWSKLDVNLADSVLTILNNYLAGMPRPDFIGPISVTSLDFGTMAPNMELIDVKDVNPEFLQNDEFPETTMERLSPKQLDARYQHLPFHVRQGPDEFGAPPPPSPKADWTSDLERKEAASPSSLWPPLQLHFHLAYHSDLRLTMTTSLLINYPSPLFLSLPIKLHLTSMQLNAEVIIAFDSMMGKRRLHFCLVEESDPSMMHPSPSAEHLGALPTPEKPPPVGMRMLPQIVIESEIGDADKHALKNVSRVERFIQDAIRNLIVDELVFPNFQTIVFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWD7</accession>
    <name>M5FWD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629123.1">
        <property type="nucleotide sequence ID" value="XM_040770104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWD7"/>
    <dbReference type="STRING" id="1858805.M5FWD7"/>
    <dbReference type="GeneID" id="63685166"/>
    <dbReference type="HOGENOM" id="CLU_497841_0_0_1"/>
    <dbReference type="OMA" id="NERHMAC"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="547" mass="60938" checksum="6653524DC8084536" modified="2013-05-29" version="1">MANDLEDTGMYVVSVKEQEEVTVKSWASEYEGNGVELFHKHITDCCEMCQGPGSSIYAKTVVIVNSSGMGKTRMIDESSKSLFTVLFVLRDTAGGFPPSDSDVLAYFQSPRTMEDCQTAILCFLKTLYDNLADMLKKQTEKMEKRKHAEIAHWFRGYLGSWDQMGAPSQERKRFFESVVNGANNMLQAQGAMPDPTFTGGRDAAGLSPRLPATDLSYQSQMIRSFQTLSELLSHEHPGHLPTVLLAFDEAHTLLRPIDKQDRRTTIHTVLRRVFRSLNNERHMACFLSTSASITQFAAPMRLDPSSRIQWDIYHTLPAFSSFPLNMARIQPHEMDLTAVGKIDFMCKQSRILFRTRAEHGVHNEVGRNLVRFAKDKLLGASDTSEYDDAQNLAILARRIPIDIRTNTSSALTSTNQQIAQHMRVLYKIKDKNESLITGSPSEPSISEGAKSAMSSGSFDAAIALRRILGSPGISVGERGEMVVELLMILASDAATKHGKFSIPDFFQNLLTEDSWKTLRSSKASRGGELHNKPFKSTFQTLLGTSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWP9</accession>
    <name>M5FWP9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_24810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624759.1">
        <property type="nucleotide sequence ID" value="XM_040773863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWP9"/>
    <dbReference type="STRING" id="1858805.M5FWP9"/>
    <dbReference type="GeneID" id="63688925"/>
    <dbReference type="HOGENOM" id="CLU_020695_4_3_1"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044843">
        <property type="term" value="P:cell cycle G1/S phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20559">
        <property type="entry name" value="CYCLIN_ScCLN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="127"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="222"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="226"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="482" mass="54363" checksum="F9355EB31945242F" modified="2013-05-29" version="1">MKTRSNPGQGPLKSNRVHAYVRQAKKTHAVSHQSLAPSGSRAGMSPGLAATIAKLRYSPPAAIMVEINKQKKQKQLMTRDAMLLQEEEYAEEVLEYWREREANTHPEVPNMDMQPELGWEIRPCLTDFLIEVHLMNRMRPETLYLAINIVDRYISKRVVLKKHYQLIGCAALWIAAKYEDEKSRIPSLAEFVDHCHNQHDQSAFVQMERHVLATIGWDIGHPTAESWLRVKCSGESYETPRTQHVTRFLMELTLFKREFVHLRPSQIAHGSLCLAKYILGESRLSRSEDTTESREVSEALDELCSEGVQRLSETVCKKYQPHYYSGASRIISEWYARGNRYHYSPFPEWNIDLPSSSEAYKTFYDSSLSRSGSSMDSISSTLSASGSSDAGDSMPATPITPIYPSAESYVSASGKENQAQGMLFGITPEMAMRAKDEPIAKSDEVLVPINHNNKVYSMRSSFIVPQPSAGGSHAVQYDFSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWS7</accession>
    <name>M5FWS7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_53735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627756.1">
        <property type="nucleotide sequence ID" value="XM_040775197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWS7"/>
    <dbReference type="STRING" id="1858805.M5FWS7"/>
    <dbReference type="GeneID" id="63690259"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="48"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="446" mass="49448" checksum="0E0BB52809C2B37C" modified="2013-05-29" version="1">MVASKDDGQKRDAAVQLEHSQKDKAHLVDLAWTSKRERRLVRKIDAHLLPMLFLIYIFNYLDRTNIGNARIAGMADDLQLDGSRYNWALSIFFFGYLILQGPSNLILAYTKPSIYLPIIMICWATISACTAAVQSYQGLLVVRFFLGVVEAGVFPGAIFLLSSWYTRKELAKRVCLLYTGSIVSGAFGGLFAYGITNNLVDARGITAWRWLFLIEGVATIAVALLAIVILPDFPLSTRWLSTEERQIADLRLARDGHERGKKRQISLRGLKLALRDWRTYLFILPCMTATCAGTFTYFIPTLVADLGYTSAIAQAMSSPPYVWAGIVVMTNGTVCDWNQQRAWHSAVPITIAGIGFILLTKVTNDAVKYFALFLCGAGVWAPIPIILSWLSDTMRFPPEKRAFAIGFVNTLSNLSSVYGSQLYPSSDGPQYWQGHAANAAFCFSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN9</accession>
    <name>M5FXN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24728</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625174.1">
        <property type="nucleotide sequence ID" value="XM_040773820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN9"/>
    <dbReference type="GeneID" id="63688882"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OMA" id="ELAMINW"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="144"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="663" mass="71446" checksum="6D90FD2915ADE572" modified="2013-05-29" version="1">MPLHIAINPEPNGSAGTESIELTSPLSPQISPTLHDVNIHGPEAFNIEAGTSVGTDTDDAGVVRPKPAIVGDKLSVLTNIEKGSELDYLSLRPRGFSMKASTKPTLDSPSTPPSEHPTPSKERDGGILLQDQSNFLPTKQVVIVFLGLGVALTCSFLEQTMMATSLPIVSAALNSGPAQAWIITAYLLVSCAVTPLSSRFSDIFGRKVVLLFCLAEFWLFSLACAVAQTTTQMIVFRALAGIGGGCLINLALIIISDVVSLRDRGKYQGIFEIIAAVSSGVGPLLGGELAMINWRWIFWLCVIMSALATVIVWKILPLKHVTGHVKNKILQIDGIGCLLILAGCVMLLLGLNWGGVIYAWVSAPVIVTMVVGVLLMAAFMVFEAYVPRIPIVPISIFKYRTVVGVIIQTTCMGGLQYCLLFYIPQWYQVVYGLSSLRSGLMLLPYICVIAPTVLICAQIIAMYGIYRPQIWLGVCMMCVAMGLFTTIGTSTPISTVLGYEALSGIAAGCIFQTTLSALQGAVPRHEVSVATGFRNFVRLLAGTIFLAIGSAIINQSVNGIGLSQGLITQILNNPPSVHTLPDIDPVTRTRIIDAYQGGFRTVFWMLLGNACLMAIVSFTMIQHHSLRRDDDAALKAAGHKFMEERKARKEAKKSHKDLEAQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY14</accession>
    <name>M5FY14_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_33008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628321.1">
        <property type="nucleotide sequence ID" value="XM_040774365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY14"/>
    <dbReference type="STRING" id="1858805.M5FY14"/>
    <dbReference type="GeneID" id="63689427"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OMA" id="CKEIRVQ"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="204" mass="21869" checksum="015302037711BDAA" modified="2013-05-29" version="1" fragment="single">TKLVAVLGATGTQGGSVVTSLLAHGGYSIRAITRDTTSAKAQVLKSKGVDVVSATLSDKASLVEVFEDAYAVFGVTVPFTQDSEEVQGHNIVDAAKEANVPLLIWSSLPNSTERSGGKYTTIHHFDQKSAVDKYIAASSQPTVILHTGGFAENLIKYRQLQRDASVPNKWNIVYSGLRPDVLVPCIYIGADLGNIVVAMIEHWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY63</accession>
    <name>M5FY63_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <ecNumber evidence="6">5.4.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cofactor-independent phosphoglycerate mutase homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_21366</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="6"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629895.1">
        <property type="nucleotide sequence ID" value="XM_040772361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY63"/>
    <dbReference type="STRING" id="1858805.M5FY63"/>
    <dbReference type="GeneID" id="63687423"/>
    <dbReference type="HOGENOM" id="CLU_026099_2_0_1"/>
    <dbReference type="OMA" id="FMDGRDT"/>
    <dbReference type="OrthoDB" id="1886626at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1450.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="entry name" value="BPG-independent phosphoglycerate mutase, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637:SF0">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="16">
        <location>
            <begin position="7"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="BPG-independent PGAM N-terminal" evidence="17">
        <location>
            <begin position="86"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="13">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="261"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU03001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="57727" checksum="DD1BE957F2BA7036" modified="2013-05-29" version="1">MVQVKNKVCLIVHDGWGVARHPGLKGNAIEAGDSTTMDELAKKYNYRLLEAHGLAVGLNDGLMGNSEVGHLNIGAGRIVWQDIVRIDQAIRKHDFHRDDNIVKSFQHAKNTNGRLHLLGLVSDGGVHSHIEHLFALLETAKEQQVPEVYVHFIGDGRDTDPHSGLKHLQHLLDFTKKEGVGKVVTVVGRYYAMDRDKRWERVKIAVDALVRGEGEKTDDLLKTYQERYDKDETDEFLKPMICGGSETRIQDNDTLFFFNYRSDRMRELVTMFGLPEKPIEIDIPKNLNITTMSRYNPEWTFPVAFPPQGMSDVLAEWLSKKGVKQCHIAETEKYAHVTFFFNGGVEKQFPGEDRFMIPSPKVPTYDQQPEMSVQEVADKVTEEVKSKKYEFVMCNFAPPDMVGHTGKYEAAVKAITATDKAVKTIYEACEEAGYILVVTADHGNAEQMINPETGEPHTAHTTNPVPLIITGSTGALRVEQEKAGEEGALCDVAPTVLDLLGLDIPPEMTGHSLLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYS9</accession>
    <name>M5FYS9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GSKIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625604.1">
        <property type="nucleotide sequence ID" value="XM_040769090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYS9"/>
    <dbReference type="GeneID" id="63684152"/>
    <dbReference type="HOGENOM" id="CLU_155989_0_0_1"/>
    <dbReference type="OrthoDB" id="5804279at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2280.10">
        <property type="entry name" value="Hypothetical protein (hspc210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007967">
        <property type="entry name" value="GSKIP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023231">
        <property type="entry name" value="GSKIP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05303">
        <property type="entry name" value="GSKIP_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103107">
        <property type="entry name" value="Hypothetical protein c14orf129, hspc210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSKIP" evidence="1">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11435" checksum="76BF03F6DBA53CAE" modified="2013-05-29" version="1">MTSVASSSSFYRDELFRALQEQGDAISSYHMTESSASSASAEVQLLEKHTATIIISIGGYQSLTDGHISTTYETLDALLGSISKLYGEKKREVLLAKLGALAGSDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ47</accession>
    <name>M5FZ47_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_119835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623660.1">
        <property type="nucleotide sequence ID" value="XM_040770874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ47"/>
    <dbReference type="STRING" id="1858805.M5FZ47"/>
    <dbReference type="GeneID" id="63685936"/>
    <dbReference type="HOGENOM" id="CLU_007057_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="566"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="1122"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1044"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1248" mass="136558" checksum="91AB2C543FE00A60" modified="2013-05-29" version="1">MYINIRSLSPSPSLTMATYPLPRTYNTLMLLAAYLIGILGTYTATQLMAQVPSTRRLGRKLAWAAAAAFSVGGTAGVGMHWVKMLAAIYPYRASYHLPLPLLFGTLMVLLTFLILSIDILLEARARALEARRFRFSLLVPASVGEEIGLLPASHSEVHEKEAAEATATAVAAESPGLRRRPTPSPEAQSSNSSSQNPNHAVMVHGLYTPDLTPPAEEGPDITPSSTASSTPTPPTPRAGNASCLPIAPRPQHAPALALPPMSASAPPSVSASPRPPSPSRFHAHVHHHHPHLYDPPTSHPHHHSPTPPAHAHHPHPHPHTQGQGQGQDRPGTPGSLSASGSSNQAELFLPPPPSPGPNLAHQRAQISRLPLGRTILGWAFWSVYLSVSRQMLVKACVLTIFCWLMHMSALLSLHFPELDAAGIRYGYRWDPRMLLASMSTELLAALGVCAWVDNTEPNPLGQVWFAVFLPTAASTVHFLCVWSGTLWISTPPAPLPPSPSADIPSLILTLAVTTYVLSYATLAEQITLSRNRLAETIFTKRRLWRVIAEKEACARANMQKSEFIAVASHEIRTPLHAILGFTDLLLQTPLTEEQSTCLEAIRMGCNSIQLITNNVLDFSKLEHNTRDSAAHATEVNVRTLSLRILRSVSAPQRMTEHQLRRLVNYNLPQDDESPSLHLPDEKHVELLLEVHEAVPELVRLDEVYITRVVMNLISNALKFTDDGFVFVRVTIEHSKHEPAGAKPVLAIMVRDSGIGIPSESKQAIFEPFRQVDGSLTRTHTGAGLGLAISKQLCERMGGTIDVRSKPGVGSEFVVRVPAFEGVGEVPDPLHMPRTPFSFMTVAVAVRSLKTFHLYKELLERRGFLLRPIDLDHPEKELQVSLAKVDRLLVDVESLAVAPWLLDWIIRLPQIPSESAPISVFVLIDDLSTEVGQQLIRMLKGSGQVALVHRPVMVHTLLESLKDGCALSPQSTGIAPILRHITTPLNFPKSGGKSESEYEYFPAVLDSEAAQQPPAPRRNSGTLDWEDTVGRILNPLEPVVQRARVPPSDKRVRFESQAPPPRNGPSPIRLRPPAIPALTISPRALVAVSPSTEPSPIRVVAPLLPLPPVLEQVPKTPPTPKKHILLVEDNVVNQKLGIRLLQKLSHRCDVAENGKVALDMLQANEDKYSLVLMDCQMPVMNGFECTRQIRSLEHTGVRKGRLPIVALTANVSSESREESQQAGADFFLPKPLLLQDLKDTLNQFIAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C4</accession>
    <name>M5G0C4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serpentine receptor class gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_82382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626179.1">
        <property type="nucleotide sequence ID" value="XM_040776563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0C4"/>
    <dbReference type="STRING" id="1858805.M5G0C4"/>
    <dbReference type="GeneID" id="63691625"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_1_1"/>
    <dbReference type="OMA" id="IEITTHT"/>
    <dbReference type="OrthoDB" id="3354175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30316" checksum="6FFFB35399B1B94F" modified="2013-05-29" version="1">MAIRFPLDQAFIVGIWLEGCFYGIFIPIFGASVYVLVAKKGLLVKLNLPILIAAILMFALATAHVTINVYRLIHGFVLNESVPGAAVLYLYSLSEPTQKAKDIVYVTQSLLGDGLNIYRSWLIWNKNWRIPVFPMLLWLTTCVVGYYIPGYLFQFYQTDSNIFGSRYRTYVTIWYTLTMVQNIITTSLIAFRLWRHERQIGDYRTGNFSLTSIIQIILESAAIYVAAQVVLLVTYACSDNAQYVLLEIITPLVGIVSHRHLQKHCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0D5</accession>
    <name>M5G0D5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_95144</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
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        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF24807">
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    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="198"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
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    </reference>
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        <location>
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    </feature>
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        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lucas S."/>
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                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="252" mass="27746" checksum="069EE9DCBE83DC62" modified="2013-05-29" version="1">MVRISVFLEREKNRPSHPPSRGARAFASAFPSPESFDLTSMVKPPSRMRTAPVHAFSNLRFSLGYSPKNSPIIRLLHGGTTRRSISGQIPLDRSPMFLDDQPTPDTLAGLLSGPFPPLDPGSSGISTPSPNTRKPSITELATAYPLTSIEKWTPLNKLPAMAKTILDFVDSNRLPHPSLEKLLPIDSIWARRVHFPMVGSREAATEAYVDRYFLEPSSHILALLTRCAYGTEPEFTIKGGSCDRVVISRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G212</accession>
    <name>M5G212_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629152.1">
        <property type="nucleotide sequence ID" value="XM_040768426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G212"/>
    <dbReference type="GeneID" id="63683488"/>
    <dbReference type="HOGENOM" id="CLU_1845018_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="139" mass="14850" checksum="16A1C53A2274EDF2" modified="2013-05-29" version="1">MMLMVSHTAHAKSNPPLVLSPTHIISSLSTSSCTSTSSPSANEAAQNTLPPMAKTAILPPTHTQMSTNNPVRAIPNTLRNDARGIGVRKAESMKVKCICTPRGEATIFLHLCSTFQHAFPDPDPTLSPAHLLLTVTSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G277</accession>
    <name>M5G277_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624765.1">
        <property type="nucleotide sequence ID" value="XM_040773866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G277"/>
    <dbReference type="STRING" id="1858805.M5G277"/>
    <dbReference type="GeneID" id="63688928"/>
    <dbReference type="HOGENOM" id="CLU_123128_0_0_1"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="16147" checksum="5DF0786FB60A90AB" modified="2013-05-29" version="1">MDHVALHNTTNLEHKHGFRPILPHKKQYLFHVSSEDEHNEWIALINFAGRFKIAGVRMRSAGMTMHQLRLAALVAAKSHVREVRSASGASSPAHLSRVMSVDDTPPTASPGELTPVDSGGTDSATAVSNSPSLPSLPDPADQLSGRIKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2P4</accession>
    <name>M5G2P4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627014.1">
        <property type="nucleotide sequence ID" value="XM_040773304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2P4"/>
    <dbReference type="STRING" id="1858805.M5G2P4"/>
    <dbReference type="GeneID" id="63688366"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="APHIRRY"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="317" mass="34585" checksum="DEBAD6BE4AC571F9" modified="2013-05-29" version="1">MGQALSELFPPKPKWTVDQIPDLSGKVAIVTVGNTGIGKATCKHLLLHNAKVYMASRSPERAEAAIADLKTITKKDDIHFIKLDLADLENVKASAAEFQSKEKELHMLYNNAGVMSCPMDMLTTQGFDLQFGTNAIGHAYFTKLLIPTLLETAKTTPGGMVRVINTSSGGHVGAPKSGILWETLKDGPERNKKLSRTSAYFQSKWANVIFSNELARRYGDQGVVSTSLNPGAIDTELARYIPKWAAPLMILFKLLLSPADPNGAMTQLYAGTAPETASANGKYFIPWAREGLPRKDTDNEGAEKKLWDYIDEVTAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2R2</accession>
    <name>M5G2R2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629878.1">
        <property type="nucleotide sequence ID" value="XM_040772352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2R2"/>
    <dbReference type="GeneID" id="63687414"/>
    <dbReference type="HOGENOM" id="CLU_041818_0_0_1"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="48083" checksum="05C5798D8DC8F8A0" modified="2013-05-29" version="1">MPFVDLPEDGVSYFYRSNLPGDGSIKGLDKTKQTIVFTLGAIFDSSSFVNQLKDPRLSKNYNLIALDGRAQGQTISEPEPGRDAWTDGVELVKLLDKLGLRHVHLFAGTWYTYHNTLRAAILFPGRLLSIAAGPIERPRDEIMMQLEEICKELLTLLATSKDIETMEDYLVEVFPYLFGEHLDEDQKDDFAAYLETQYPPTRLCRGMEFGNAIFGNRIPLTDEEADLVRVPVLLYAADNLVDTVAEAEAFANRLTGVPGGCQKHILPDGAPSEAWYIRRYADGVTNAFLDFIQKVSETPQTVAPTNLEAALALNAKLADEPTMAQLDPKKSMSFSRVPPAVLAQRNQVFAICSEAQKRGFDPIGLNGEMPRRFSDRYHERNRQRATSTASLVIQVSVSHKSEEDLAKAGVDAKKAEEDHDLSSITDKLKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G382</accession>
    <name>M5G382_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_57834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625095.1">
        <property type="nucleotide sequence ID" value="XM_040775468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G382"/>
    <dbReference type="STRING" id="1858805.M5G382"/>
    <dbReference type="GeneID" id="63690530"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OMA" id="SHFHGKN"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="311" mass="34526" checksum="7CA4AA98FF9D02F7" modified="2013-05-29" version="1">MYQAFTEMCPPAPKWTVGDMPDLAGKVIIVTGGNTGIGFITCKYLLLHNATVYMLCRSPNKAQDAIHQLQDVTGGKEAKFIQCDLADLPSVKRCVQEFTSKEQRLDVLFNSAGVMFPPIEQVTKQNFDLQFGTNVIGHCYLTVLLLPILLSTAQESGNKVRVINTSSDGHILFSPKEGINYDVLSDSPERRKMATTAMYGMSKWGNVVFSKELARRYGSQGVISHALNPGHLRTELQRHGSGLSKRIADMLLFELDPLGALTQLYAGTAAEAGEVNGQYYIPWARHGQANDPEAGKQLWAWLEKELKKYWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G452</accession>
    <name>M5G452_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629884.1">
        <property type="nucleotide sequence ID" value="XM_040768214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G452"/>
    <dbReference type="STRING" id="1858805.M5G452"/>
    <dbReference type="GeneID" id="63683276"/>
    <dbReference type="HOGENOM" id="CLU_030360_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="65942" checksum="D50218A66416BEB9" modified="2013-05-29" version="1">MPERQQPEQRSALLSQAIDICTSLCDVLERLGPSRFTQLDSDIGVSKVHKLESDLHSRLQRVDEKRNDALAPISRLSDDIIRLIIQYGHDDEILDYRKVTVKTFARLVSCISRRWRAISIDMSNVWTDLVFSNPKYLGDEDSKPTHPWYGSAKVLSGMYTSNLERSKQSLLNVQLYIPQLLDPRIMIKEYLHVCTNRVADLNLEANTSSAESMNAIVPCVTQTRETLRRLRIVLEQSTADDGGRDLIETLLLCNLPRLVDVHLQTIPLPLVHRPEFVGFLQCRRLRLEMFHLRQYTPARLVGLLKCVPRLQQLHLVVFPHESDQVAAEPNIHGPRLLLPELRTLKFISSPVGRHTLGQLLFPKIESLSAFILSPSVSHHQETAYVGELRKFLTASSSPDGMPPPVKALSVDGGILRSLHRILRVIPGLEVLQIVFDHDWSPVEEEQRVAFLNKLGAQPLSPKGNITSVDGEPYSVLCPNLQALESLAWAKPSHIQSLTTLASRRRSFGMPLTRIRMLNWPLSAAPPETVGMPATPSEEYALEKALAREVEILECGEFRWEWKEGGRWFKAPRVGDPRFLSDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4M9</accession>
    <name>M5G4M9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_13301</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632095.1">
        <property type="nucleotide sequence ID" value="XM_040770972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4M9"/>
    <dbReference type="STRING" id="1858805.M5G4M9"/>
    <dbReference type="GeneID" id="63686034"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_4_1"/>
    <dbReference type="OMA" id="TICLTAM"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF108">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0288">FMN</keyword>
    <keyword evidence="7 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="14 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="10 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15 17" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="13 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU05201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="56624" checksum="A1D43930BD1C16FB" modified="2013-05-29" version="1">MSEPIPSPPSYPIIGHAGTGVYDPVASAKSRRQLREKYGSIYRLNFFGREIIFCSSQEIVNELCDESRFQKEVAGGPLEEVRNGIHDGLFTAFGTEENWGIAHRVLLPGFGPAQIQGMFLAMLDINAQLLLKWERFGPDHVITPTEDFTRLAFDTIALSMMSHRFNSFYMEEMPPFCQAMTRFLIESGVRNQRPSMIQNLMRAENAQYEADIKFMADVCDQRKHSREKRGKSLMVLVVVQNRKSHPTSKKDLLTLMLEGRDPKTGRGMSEANIRNNLITMLIAGHETTSGLLSYTLFHLLSNPSTYSKLQAEVDAIVGKDALQLAHVPKLEYTQAVLRESIRLNPPAGMISVSPVEDTVIAGKYAVKKGAMLAVDIAGLHRDPAAWGDDVEEFKPERMMSPHFEALPVIFLVCVPPDRHLRGFSFQPNCWKPFGNGSRGCIGRPLAWQESVMMLATLFQHFDIKFDDPSYKLRVKQTLTTKPEGFQIRTIPRKDAPPIVGAGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Q5</accession>
    <name>M5G4Q5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24297</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625615.1">
        <property type="nucleotide sequence ID" value="XM_040773630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Q5"/>
    <dbReference type="STRING" id="1858805.M5G4Q5"/>
    <dbReference type="GeneID" id="63688692"/>
    <dbReference type="HOGENOM" id="CLU_051898_1_2_1"/>
    <dbReference type="OMA" id="FKSQYWR"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="216" mass="24606" checksum="8969D3F8D3F0DE60" modified="2013-05-29" version="1">MPVGLEAWLTDIPPITRAWLIAAIGTSLAVQCHLITPLQLYFSFRSAFIHLQPWRALATFLYFGPLSIDFVFHLFFFMRYSRMLEESSFAGHKAEYFWLLFTSATLLLLLSPLFTLPFLSSPLAFTLVYIWSRRQPAMRISLFGIMTVSAPYLPVALVAISWAINGTWRAAASDLMGCVVGHAWYFGTDVMLREVGGRMPWTKTPAIVQRWFRDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G534</accession>
    <name>M5G534_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_49590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040774914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G534"/>
    <dbReference type="STRING" id="1858805.M5G534"/>
    <dbReference type="GeneID" id="63689976"/>
    <dbReference type="HOGENOM" id="CLU_067577_2_0_1"/>
    <dbReference type="OMA" id="DQYEQRT"/>
    <dbReference type="OrthoDB" id="5295208at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.190:FF:000013">
        <property type="entry name" value="Tubulin-folding cofactor B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="6">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26360" checksum="F2252645B053763C" modified="2013-05-29" version="1">MSATSVSVFVSSPDTHSERKFDLHTTIGQLKTRLEHITGITPTSQKLVLSRTEDGQQIRVLDDDSRPLGFYSPADFQTIQVVDLNPMGPAGMYSDVSQVEKFELSDEQYAKRDESLLKFKQANKFGRFADEHQQASAPAASTASYPDIKVGARCEVESEEEGLQKRGTVRFFGSTAFGKGTGLWVGVEYDEPMGKNDGSVQGHRYFTCPTNHGAFVRPERVTVGDFPPITLIDEDEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B1</accession>
    <name>M5G5B1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_82779</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625840.1">
        <property type="nucleotide sequence ID" value="XM_040776591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B1"/>
    <dbReference type="STRING" id="1858805.M5G5B1"/>
    <dbReference type="GeneID" id="63691653"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="EESQWKH"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="57780" checksum="87CD7AAD4CDA6D9B" modified="2013-05-29" version="1">MSAMLTFQISWGTVVEAAAVAAVMLVLWRQVRPSSRPPLPPGPRPIPLIGNLSLPKDYRVTFRELADKYGEVVNFCIFGKNLILLNSKRAVTELLEKRATTSFGRQKLVMAHELVGLKYMFSQVSDPVLHRQYRRVFSAVFGPRPSRAFWDIQTLQIRKLTAKLLTSTSEYSAHIDKATAAISFLIAYGKDLDQEDPSLVKKIHGFMGLLMRLQAPGAFLVDLIPGLQKLPEGWPGTKFKQQAKVWRKEVDEVMDVPYQSVKQDMASGKADPSYTLSLLEGADGKDTDEIVIKWTAGAIFNAGSDTTAASIHNFLYAMMMFPQVQAKAQQELDAVIGRDRLPTIEDRDKLPYCWAMTQESLRWQPVAPLALPHLMLADEIYEGYLIPKGAMIMANVWLLAREEREFPAAAEFQPERYLSKDAKPSEDAEQTRGPSFGFGFGRRACPGSYLAEDSLFAAVVTILWSSIVSIPAGYSKETLDPGYPKKPAVHRPVQFPIDVKRRFPTALEMLKQSIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5T8</accession>
    <name>M5G5T8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_105738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630474.1">
        <property type="nucleotide sequence ID" value="XM_040768136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5T8"/>
    <dbReference type="GeneID" id="63683198"/>
    <dbReference type="HOGENOM" id="CLU_008523_12_3_1"/>
    <dbReference type="OMA" id="NTINDVW"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067582" evidence="6">
        <location>
            <begin position="19"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="493" mass="54816" checksum="DCFA55999FBFF818" modified="2013-05-29" version="1">MTLLASLELLLLCIPILAAPSSILDTGPFSWPFFSWFTSPAGFPDEVAVLRLAPFSDPAARAFLVNSSALPLVDFDLQESYAGLLPISAEEGEARKLFFWYWPTSAPEGSKHLTIWLNGGPGCSSLMGFLQENGPIMFLPGMDKPEYNPEGWTTATNMLYIDQPIGTGFSAGPASVRNEEDIAEQFYGFLQQFYTIFPELLSKPLIFAGESYAGYYIPFIAHRILHASQEEQARQAISVHALLMNDGCYSSGIVMQHAPTPAFARLHQATLNLTTAQILELEQRRASCGYDALLAQIRYPPAGKLTLPNNVDYTPYECDLTDLFKQWCREANLCFKEEKVGQGCLKENPLDTYFSRSDVQSLLHLPPSSWSECTSHSVYKSGKDESAVYSETLLPELVDRLPGGVTLWHGVLDALLLAEGDRLTIQNLTWGGEQGFQEEPHTPLYLGREKKGLWHEERGLTYVEVYDAGHMVPQDQPEVALRVLKYVLGLDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6F6</accession>
    <name>M5G6F6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_82487</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat NOL10/ENP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626245.1">
        <property type="nucleotide sequence ID" value="XM_040776572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6F6"/>
    <dbReference type="STRING" id="1858805.M5G6F6"/>
    <dbReference type="GeneID" id="63691634"/>
    <dbReference type="HOGENOM" id="CLU_009923_0_0_1"/>
    <dbReference type="OMA" id="GYFMDVR"/>
    <dbReference type="OrthoDB" id="273340at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056551">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040382">
        <property type="entry name" value="NOL10/Enp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056550">
        <property type="entry name" value="NOL10_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23098">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23097">
        <property type="entry name" value="NOL10_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nucleolar protein 10-like N-terminal" evidence="9">
        <location>
            <begin position="21"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar protein 10-like second" evidence="8">
        <location>
            <begin position="396"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="7">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="488"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="553"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="590"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="612"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="734" mass="80982" checksum="A49F19865EC55AEF" modified="2013-05-29" version="1">MASAIDSSSVKVYTVNGAPSASSSALPDWLTRKRQQNGSKRTRTEHIEGTIELVQHFEFPEASNRIRTTRDGHFAVATGTYKPQMRVFDLDQLALKFERHSEAENVDFLILSDDWTKTAHLQSDRTIELHNQSGFYYRTRIPRFGRAIAYHSASCDLLAGGSGSDVFRLNLDEGRFMMPLDLSEGGADFEGVNAIDINPAHQLFAFGTSGNGTVQFWDPRSRSRVGILRIPLSQLLPTGGLGSTGMDTDPAVTALSSRMDGLNLAVGTSSGHTLLYDLRSDKPYAMKDQGYGLPVQSVAWIEGGHKMASENLVVSADKKVLKIWDRNTPGTNFTSVTPANDINHVHHLPGSGLLMLANEGIQMTTLYIPQLGPALKWCSFLDNITEEMEEQSTRNVYEDFKFVERSELSSLGLDHLVGTPALKPYMHGYFVSAELYSTARLIANPYAYAEHRERLVQEKLEKLADTRIRARKDIPGVKVNKSLAERLRKSEEKAARKAKTEGGKPEKGELASDPRFKELFENPEYEIDENSREFTLINPSTAAQKAKFRRDEDESESEEEAPEDGDDDVDMSEESSEEDYPPARQKEQIKATSTNPIAKTSSRPSSGRRLVSSFSRFGTSRTSDTGATLGQLRRTSSSHTPKARQVVSRGPAVSNARATADGGLEMSFIPSSSGAEKGGRGQQHGKAKGKKPEMFGAGLQKGAGEEEDRDIGRGGRTKRRTGVRSGSKNFFRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6L4</accession>
    <name>M5G6L4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL34m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_64047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631233.1">
        <property type="nucleotide sequence ID" value="XM_040775749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6L4"/>
    <dbReference type="STRING" id="1858805.M5G6L4"/>
    <dbReference type="GeneID" id="63690811"/>
    <dbReference type="HOGENOM" id="CLU_129938_0_0_1"/>
    <dbReference type="OMA" id="RAKGRMY"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3980:FF:000001">
        <property type="entry name" value="Mitochondrial ribosomal protein L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="131" mass="14576" checksum="EB2627FD1F1A01BF" modified="2013-05-29" version="1">MPRQLLNRAIRAAGRTAKRLAAPTTTAPAYISPVARPTSSLTLPMPIRSLTPFASPRSPLSAFGAPLPRPTLPSPLASVLPLLQARFLGNEYQPSQRKRKRKFGFLQRLKDKNGRKTLARRRAKGRRFLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6S3</accession>
    <name>M5G6S3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631298.1">
        <property type="nucleotide sequence ID" value="XM_040769866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6S3"/>
    <dbReference type="STRING" id="1858805.M5G6S3"/>
    <dbReference type="GeneID" id="63684928"/>
    <dbReference type="HOGENOM" id="CLU_081626_2_1_1"/>
    <dbReference type="OMA" id="PHDPHAY"/>
    <dbReference type="OrthoDB" id="10261524at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022976">
        <property type="entry name" value="NADH_Oxi_21kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="189" mass="20949" checksum="7AE6FC92AE0231FB" modified="2013-05-29" version="1">MASKKAIEHFADHTKYHLAPHGFWKRFRDAVVINPNVSSGLPVASVNRYPQPGSRPEKYATPASQASDPAQNPYHKRDFRRAYPQVSTVSQPLLTSLLLQSPTLAALHAPEAAASSLSADPTLSQLPVPLPDKLPDLTEALQELSEKTKLFDGKNLPPVPPRVRKWTGMVPGEEVPRDKHAYFPMELFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6W9</accession>
    <name>M5G6W9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628459.1">
        <property type="nucleotide sequence ID" value="XM_040771177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6W9"/>
    <dbReference type="GeneID" id="63686239"/>
    <dbReference type="HOGENOM" id="CLU_799314_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067503" evidence="2">
        <location>
            <begin position="31"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="37445" checksum="7D1C7FBA50067A0A" modified="2013-05-29" version="1">MPLSFTPVTLQATLAFLSSSLSSLTTMVMSSSPPPSPLSYHTVPSNPMVSSQDNLQLVSSEKNAILDENLLHKTGRGLLLIITSVPQDKGKGKHKDMYALEVVAGKGSLSKIMDQAVLKEALVNIIEHVQIKAGGEVLVNGYSLVDWLRHGGLPKAALQDLALVDENDEDIPVAIPTAVPTPIPTVKPMAKPTPTAVPTKCPCLLGSALTGPMVEGLEVKCTPPHDLGKLREEEFQKELNHIMLPAFMIGRLLKEVDIALEEEWSEAKVHVCHLAQHNEVWTSHVEMGRKYQQELYNTSQSQSQSAAPAPQPSDTAPKTDTQPAAGPYGSQPAIDPSSSHKHKLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7B3</accession>
    <name>M5G7B3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_45474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633015.1">
        <property type="nucleotide sequence ID" value="XM_040774645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7B3"/>
    <dbReference type="STRING" id="1858805.M5G7B3"/>
    <dbReference type="GeneID" id="63689707"/>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OMA" id="CALSECK"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="293" mass="32547" checksum="C4AC1DA0ED42FD57" modified="2013-05-29" version="1">MVYHKTVTLNTGAIMPTVGLGTWKSAPGQVEHAVEYALKEGGYKHIDTAYDYGNEAEVGQGIKASGVPRAEIFLTTKLPNGHHHTPEKALEESLAALDTYIDLWLMHWPAPMKNGKADKSANWIDTWKRMEVIYENNKDKVRAIGVSNIGVKYLRQLLKEAKIVPAVNQVELHPSCSQEALVKECREHGIIVTAYSPLGSDNSPLLKDPVVTTIAAAHGVFPANVLISLQANREGVTVLPKSVTNERIKANMNIIDLTDEEIRELNDIDKTKHFRACRPHWTGWGSLGWEDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7J7</accession>
    <name>M5G7J7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628749.1">
        <property type="nucleotide sequence ID" value="XM_040772732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7J7"/>
    <dbReference type="GeneID" id="63687794"/>
    <dbReference type="HOGENOM" id="CLU_2654456_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="76" mass="8923" checksum="772A6E8FCC4CB8F1" modified="2013-05-29" version="1">MRNSHETSLAWTIRLIHQLHPTTVQRVPDHCMHAMQEHTRPHERVHPASAPVPWTIRCQLTTEDTIQHRPNSHRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7T5</accession>
    <name>M5G7T5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF803-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_26545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633160.1">
        <property type="nucleotide sequence ID" value="XM_040774286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7T5"/>
    <dbReference type="GeneID" id="63689348"/>
    <dbReference type="HOGENOM" id="CLU_012349_2_2_1"/>
    <dbReference type="OMA" id="EWITYPL"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="EmrE-like"/>
    </dbReference>
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        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="388" mass="42188" checksum="1CC7CEBF7FA1DE0D" modified="2013-05-29" version="1" fragment="single">IGIGVAIAGNVVISLALNLQKLAHQRLNGTWNEGGSDGAETFNGTETPTPIGNGESTLPDENGRMHFPTFSPTEELPNPMGSPKAPKIILSAPSTYNGRHAPRAFYRPDNRSSPSARLLKQGTPSIRRYDSIGHPSIAEHDEEEGEAPVQENGPDRHYLSSKLWWTGFLLMGVGETGNFLSYAYAPASIVAPLGTVALIANCVFAPLLLHERLRKLELFGVALAIIGALTVVASSQSNDIRLTPDGLIKAIMQPGFIAFTAVYIVSVIVLMILSNREYGKAHVLVDVGICALFGGFTVLSTKGVSSMLTYKGFPIFRDWITYPFLVVLAGTAIGQIKYLNRALQKFEGKVVIPTQFVFFNLSAIVGSAILYRDFEDMELHRFITFLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7V4</accession>
    <name>M5G7V4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division control protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633180.1">
        <property type="nucleotide sequence ID" value="XM_040767728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7V4"/>
    <dbReference type="STRING" id="1858805.M5G7V4"/>
    <dbReference type="GeneID" id="63682790"/>
    <dbReference type="HOGENOM" id="CLU_043859_0_0_1"/>
    <dbReference type="OMA" id="ECNIASR"/>
    <dbReference type="OrthoDB" id="5357220at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012535">
        <property type="entry name" value="Cell_div_Cdc14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08045">
        <property type="entry name" value="CDC14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="54019" checksum="3F9F76F8B0425D01" modified="2013-05-29" version="1">MHAVIYTALDDITSSRSSHSRRYRALITLDKLLADESFETNIVSRLLSFLALSLLQLDTLSSPSLSTPSTPSRSHHHSRSHSPSPSPDAANLNNSIILSLQLLQGCAFLHPQSKAYLGRKAPLQLLLDILLASRPHHAPIGTSLLATDSRAPSSAYPSPSPVPLSPLEPAQQPTQPSQPQAQGKPSIALSILDTLLSILVDSPPSLRAFEAASGLEGVVRTLKRVGVPREVRMRCLEFLYFYLLPEGPEAEGAEGPEMLDVHRLGGKLLEGEGCSPSPLSRPPTPPPATAVPPLTNSRSSSASSSSSLETTASASAGRPFPVRGKLAFALEADGIGTGIAVGTGVGMEGFVPATPKKKLARIGMGTPRHPGSASGSAPGFGPGSGTGTGTGIGTAPGSGSGAGMRLGTGTGSRTGTGTGIGRELAGRTVPSLELTTPGKGKGKGDSLSSTSTPGGMRGLGLAIVERSLVDPERSYPREPGTGAGREGAGGAGVMRSTEEKKERLGAWLGNVDQLVEGVRRAGVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X7</accession>
    <name>M5G7X7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <shortName evidence="13">SDH</shortName>
            <ecNumber evidence="4 13">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_23436</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="4 13"/>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626770.1">
        <property type="nucleotide sequence ID" value="XM_040773237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7X7"/>
    <dbReference type="STRING" id="1858805.M5G7X7"/>
    <dbReference type="GeneID" id="63688299"/>
    <dbReference type="HOGENOM" id="CLU_063085_0_0_1"/>
    <dbReference type="OMA" id="YFFFSHT"/>
    <dbReference type="OrthoDB" id="265306at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004754">
        <property type="term" value="F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000217">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 13 15" id="KW-0520">NAD</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="18">
        <location>
            <begin position="10"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="17">
        <location>
            <begin position="169"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="311"/>
            <end position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <begin position="195"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
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        <source>
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        </source>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJT99872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="364" mass="40508" checksum="E8D28794C1B6ED13" modified="2013-05-29" version="1">MSPQSRQPLWLRCETKPFERRAALTPSTARELIKDGFTITVERDPQRIFDDEEYETVGCTLAKHSSWPEAPVDTPIIGLKELPISTMPLKHTHIQFAHCYKHQGGWREVLMRFHKGKGMLYDLEFLQDENGRRVAAFGYHAGFAGAAVGVFSWSKQGRIHNLEPYETEAEMITAVKNAIAGNPPRVMVMGALGRCGRGAVDLFKAVGIPDGNILKWDIAETAKGGPFDEILDVDIFVNCIYLSSKIPAFITADQISAAGPNRRLACVVDVSCDTTNPNNPLPVYSVNTNFRDPILLVPMGEGNPPLQVCSIDHLPTLLPREASEQFSRDLLPSLKQLPTKSEAKIWKEAEVLYRRKVAEALSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Q7</accession>
    <name>M5G8Q7_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_107161</name>
    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <location>
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            <end position="110"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <end position="110"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="212" mass="23329" checksum="F585CBF4ABFA705F" modified="2013-05-29" version="1">MPPDVNLEAAIKAEQAVWNVLPEIKKTQHLNIVQMYQMAGIERNLALLDPKVETPVPLPKKATPIPAWHSQLRVSISAAASLPSLPPKSPSVVKSTPAPDDNKKKPGKMPKNELSEELLALAAKAKPDLLPMVLQSHMLRALDGTTKATQTSAEFNVLLNLDHLCGDHLSIMDICLSPVWPVLYFMKVKGFKNINLPSPTQESHSLRHVQLQ</sequence>
</entry>
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    <name>M5G8W5_DACPD</name>
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        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor SUI1 family protein</fullName>
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        <lineage>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF2D family.</text>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21156">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000008">
        <property type="entry name" value="eukaryotic translation initiation factor 2D"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039757">
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    </dbReference>
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        <property type="entry name" value="eIF2D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039759">
        <property type="entry name" value="eIF2D_SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048248">
        <property type="entry name" value="PUA_eIF2d-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058886">
        <property type="entry name" value="SWIB_eIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057429">
        <property type="entry name" value="WH_eIF2D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26292">
        <property type="entry name" value="PUA_elF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26291">
        <property type="entry name" value="SWIB_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25304">
        <property type="entry name" value="WHD_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="5">
        <location>
            <begin position="381"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="488"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="62901" checksum="238A6BDB216B717E" modified="2013-05-29" version="1">MFKKSPSELKTSSALRNSDRRKLAGDVATAFKLAPEECDLLVPDGLQARKFKSSGGEPGTIYQSPDGEPLWFTVGKQSTTLVPTVYTLWKRPKLVSILHTPAFVVEKLSDGADLMIPGVLETAEQLPGVSKGDLVAISIIGSNVSLAIGTMAVPPSSLGKGMKGKAALILHIYEDYLWEMGSKSGPPAALPYPEPSEDLDETTSKLAALSTEDETKDALDERVPTESVETSPEESVTFGSNNEMTTPAEVDTILRTALVHAIATSLSKLPASSFPIMGTNLYSAYILPSRPSDTPADADIKHSSYKKLTKFLKTAEKDGLIKTKDVKGETWLTSVNATCPDVLQHTGYKTIADAEKKDASKKEQEKRQAARSKKDGIAITELYKPHGPSVAFFDVMSKNTDDLYNGVEVRTVLLEYVKEHSLVHPREQGFVVLDKLLQEVLLNKGEEIEFMRREDALERLRSKMQAWHSIALKEDEAPVVKKGQLAPISVVAKTRQGRRVISLVTRFELYGIEADELAEALRKACASATSVTPLPGKNAGSEVLVQGNQLKIVSDLLMERGIPKKWIQLEDTTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9D1</accession>
    <name>M5G9D1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1348-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_113527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632288.1">
        <property type="nucleotide sequence ID" value="XM_040769645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9D1"/>
    <dbReference type="STRING" id="1858805.M5G9D1"/>
    <dbReference type="GeneID" id="63684707"/>
    <dbReference type="HOGENOM" id="CLU_112790_1_0_1"/>
    <dbReference type="OMA" id="VRFQYEC"/>
    <dbReference type="OrthoDB" id="14527at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757:SF0">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="159" mass="18860" checksum="B5121CEA52592DBD" modified="2013-05-29" version="1">MSTDESKHPFPPFTLETAKQKVKAAQHMWNSQDPSKICLGYTPDSVWRNRDSFLQGREAIIQFLSAKWAREKQYKLRKELFAFTDNKIAVQFRYEYYNEAESQWYRCYGLEDWTFAPNGQMEKRQMSGNDVKIREEARWFADGTTEAEWDVVPISAAHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9J0</accession>
    <name>M5G9J0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ-mediated genome instability protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_47516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631819.1">
        <property type="nucleotide sequence ID" value="XM_040774762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9J0"/>
    <dbReference type="STRING" id="1858805.M5G9J0"/>
    <dbReference type="GeneID" id="63689824"/>
    <dbReference type="HOGENOM" id="CLU_096565_1_0_1"/>
    <dbReference type="OMA" id="KYPRGML"/>
    <dbReference type="OrthoDB" id="341511at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049363">
        <property type="entry name" value="RMI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790:SF15">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21000">
        <property type="entry name" value="RMI1_N_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01161">
        <property type="entry name" value="DUF1767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RMI1 N-terminal" evidence="4">
        <location>
            <begin position="15"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="3">
        <location>
            <begin position="69"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="19340" checksum="394B9D3241D1410F" modified="2013-05-29" version="1">MVPREIEQWTNRNYPKPQVDPEWLAQCYNYLVSELGIARNDITALTKNIESQLLQSDLHDSTLPQTGLPENPASLHAVNLPPFLLLQVVSIMEIGHSAFSLQNTRQAWIEKADLAGLAAREDDGEYSAGEFPRYPRGMLSLELSDGYNVIKAIEYRRLDGLKLGETPLGYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9R8</accession>
    <name>M5G9R8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_104040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040767867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9R8"/>
    <dbReference type="STRING" id="1858805.M5G9R8"/>
    <dbReference type="GeneID" id="63682929"/>
    <dbReference type="HOGENOM" id="CLU_006272_0_0_1"/>
    <dbReference type="OMA" id="VRPYLWD"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
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        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019487">
        <property type="entry name" value="RAM_signalling_pathway_SOG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10428">
        <property type="entry name" value="SOG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="590"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="705"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="906"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="743"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="923"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="988" mass="107679" checksum="303042F0DF61B8E7" modified="2013-05-29" version="1">MSVPSSSTLVVFLVQEHIDKAVSASEDNGETIDLSQRGFNAISDEGVGLLRRAGGGDEEEGGKVKRIAMTHVALRELPISFSTLMRLRYLNMRGNLFTTFPEVLTSMPSLEILDISRNKIKRLPVQPGNLVHLRVLCMSKNRLQRLPRYLTYFSCLKILKVDSNPIVWPPAEVVNSLQDNGDMEDWIAEVKQWMEENGPDEAERVPTGRLNTRTDDVLEASMLERTASEMSMSMTTDTHRFMFSPSAPHTRNASEESTLSFSIGSETTSRPSPRPPPLRLPAIHSARSSPSGTPDVSTQNLSGYDFALTPPASALPQLHGRGQSYSVGRRPRAQTLGAKKSLPELRTNNYGFPSSLLQSTRSRTKGVTGDTPAVPVPRLKSTSPLATPEARFGIPGELSSSAVRSGANAPCLALEKNSYFRRLSTLPPLRTSRTVPDSLLKVMDGVRTILSAAEQIYDSLRHYTVYAIDDRLAGMLVRVLEPAGAYIGRLINALDRFDSVSRKGLPQVPVCRDVLKSCQDTLALFGRLTIVLQAQLKVLAGTDDVRFTRKLNLLLYGAAGEVSYAWQEMSPYLQDIKAYLQTGSETHLSKAHARDGPMTPVIEQGEMGDPTVTPHADRSFTSTSHTPNPPSIQARRARRHGGSYSQKDVELGKALPSAGLIPSPDTPNWPTSANQPPALRSALRHAAQAHSPSPVGMTSPLLWASTQAPHSASHHSRRESDESSGHTTSPPMNGARPTRPILTPSNSSAFLSHHLQTPSPLPRSPLPLPPDSAQLFDGALLSMMDSATETANNVWAMLAELLNNLAEPRRDIRAALSKAEHATEKVREDLEAVRQDPSPAARKALGDAAHQFAKSVAQLLTLIRAYDAQKALPSELRSGVSRLTHATKNFTVFFQATSFAPRLRALSPAGGDEESHRMPMLSQGLTPRGTPTSLLRSRSDVATPSKPSLSKSVRDAPWSAQPQQTFQIPPVPPRQVESATRPTFEALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9S2</accession>
    <name>M5G9S2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_113638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632453.1">
        <property type="nucleotide sequence ID" value="XM_040769668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9S2"/>
    <dbReference type="STRING" id="1858805.M5G9S2"/>
    <dbReference type="GeneID" id="63684730"/>
    <dbReference type="HOGENOM" id="CLU_016852_1_1_1"/>
    <dbReference type="OMA" id="HSCGGHM"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="29"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="293" mass="32516" checksum="F3B0CC5D32656031" modified="2013-05-29" version="1">MSLYELLDVQYDTAASGEAGSSGHAQRRLDLFVPPVEAPPLLVFVHGGAWRSGDKSEHTALARSLALQHSTAVAVVNYRLTERNPPPGEMVEVRHPMHALDVLLAIEFLYDWAGEGEGKPELQKSFDREKLYFIGHSCGAHILTTLFLYPPALSLPPTPSHILRSTHALLLAEGIYSLPLLLETFPSYIEFIAPPFGGSSSGSSSPGSKYDIFSANHYDLRPGGEHMHWWVVHSEGDELVDFEQPEVMFDSLEILLEGEEGEVHQDWDTLKGDHYKTLDEPRFSEIVGEMLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9W0</accession>
    <name>M5G9W0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_104090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632498.1">
        <property type="nucleotide sequence ID" value="XM_040767877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9W0"/>
    <dbReference type="STRING" id="1858805.M5G9W0"/>
    <dbReference type="GeneID" id="63682939"/>
    <dbReference type="HOGENOM" id="CLU_134973_3_1_1"/>
    <dbReference type="OMA" id="MTHTYKF"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051881">
        <property type="entry name" value="Copper_transport_ATOX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365:SF1">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="96" mass="10433" checksum="41F9E15B4F2FF942" modified="2013-05-29" version="1">MSDHTYQFNVKMHCSGCSGAVQRALGKADGACPPHFRGHYLILSPCFCGMRMTGISSYEVSLEKQEVTVNTARSYEDVLQVISKTGKEVLSGTTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA60</accession>
    <name>M5GA60_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Osmotin thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632099.1">
        <property type="nucleotide sequence ID" value="XM_040771655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA60"/>
    <dbReference type="GeneID" id="63686717"/>
    <dbReference type="HOGENOM" id="CLU_1447259_0_0_1"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067659" description="Osmotin thaumatin-like protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="16833" checksum="EE24CED09B9DDAD9" modified="2013-05-29" version="1">MYSLAAAVLVFAGVASAHSFTLHNNCPYNVPVFVDSWPGSITYTGPQPGTLGPGEYYGLSIPSGWNSRICHNADGGNCWGADSMTEFNMDAGGLAYYDISNIEAFSIAQQIAPAGGGCQTVTCTSANCPCSQAYPPGDESGCGDDAPVKACSDQDFTITYCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAD9</accession>
    <name>M5GAD9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar import and degradation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632199.1">
        <property type="nucleotide sequence ID" value="XM_040771688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAD9"/>
    <dbReference type="STRING" id="1858805.M5GAD9"/>
    <dbReference type="GeneID" id="63686750"/>
    <dbReference type="HOGENOM" id="CLU_028759_1_0_1"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="54319" checksum="8A8A6BA9143791ED" modified="2013-05-29" version="1">MTFHVEIFEGDGIGGGIARQEQICARCVIRGGILGSFGEDADEAVHEFDEATDGQMPVEAEERVRCTVRPEDVEQAAVVASTDEDSNVHMDDRPIHQEQPLFTPPHSPHPDDDNINPDERYRLLFNRGLQESFTQTSGPSSPVDKNGFQPARPSTSPPSNLAVFQAAPSFARHTPPRTPSPADASSILFGPHVVQTIMEEQGPSSEVAQQRHVTLPDLYCDITHLKRRTDGRGCLYPGSVFSGTQRSGRNSYDVKVTIVDVSFAEATLTGYLLIHNLTPSHPELTTLFTADIIGGPYHGFHTGEWGATEEDDFTHWSRFRSFSGLKKEMQGPKGTIDSRERNCVYMRWKERFLVPDHRVRDINGASFAGFYYVCVDLDPACSADNGSGLTFASASQHPLTQSHLPSATRANASVTPSGGRSRAATLMGDIKSFDWTTHEREKVEAMERARGKGYGTAMMEGLYYHQNSEPYQHLSLRHMPERTSATFEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAN7</accession>
    <name>M5GAN7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
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                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJU05929.1"/>
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        <property type="nucleotide sequence ID" value="XM_040771443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAN7"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAZ3</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_113639</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Wiebenga A."/>
                <person name="Young D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <location>
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            <end position="27"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="331" mass="37189" checksum="7F99A3BD4EBB5E02" modified="2013-05-29" version="1">MRFLKYAKWILPAIIIWLSLAILYLTLPPGESIDDDVVFAQSLREGKSLNRVYHTEEFIPREYRLPRVRRRLYLGLEYSYSARTSTLRIKNEAVSLLPLLSPSSPAQSHSRLLIPWATLGDTDGVNPPWFPLADAVLLYGVVSREWGRILLTVERPLLPPNGTLDGELALQVVPARMATQSEGTEEDPVPLGMLPLATLFFTQPAEGEGYALARISFPPMPQSYGTSTYYGTRHALISLLAPSALLVLALASLAGQAVKLLLLGLGVAALLWIGRELWMYRHEQDEDRRERETQVLRKVLREVLGPLYAPRGRREVVRTGIEEGRDQKEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBP9</accession>
    <name>M5GBP9_DACPD</name>
    <protein>
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            <fullName evidence="6">Small ribosomal subunit protein mS33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_62542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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        </lineage>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
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                <person name="Spatafora J.W."/>
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                <person name="Benoit I."/>
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                <person name="Copeland A."/>
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                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
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                <person name="Glotzer D."/>
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                <person name="Heitman J."/>
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                <person name="Kallen N."/>
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                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
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    <comment type="similarity">
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    <dbReference type="STRING" id="1858805.M5GBP9"/>
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    <dbReference type="HOGENOM" id="CLU_150777_0_1_1"/>
    <dbReference type="OMA" id="MKAQCQV"/>
    <dbReference type="OrthoDB" id="2257454at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013219">
        <property type="entry name" value="Ribosomal_mS33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS33"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
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        <location>
            <begin position="71"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
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            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="12658" checksum="E5C68D14C7A40593" modified="2013-05-29" version="1">MASLATKMRQLARLRSTIFDTSYNPSSARTGAKYIRRRLLGPAMVRYYPQKIDMKLVKALAWDMDLLDPAEEERREDREMERRRGKGAPKKLKTKSEDGQKNKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBR5</accession>
    <name>M5GBR5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_104364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632769.1">
        <property type="nucleotide sequence ID" value="XM_040767914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBR5"/>
    <dbReference type="GeneID" id="63682976"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="KWLALDN"/>
    <dbReference type="OrthoDB" id="7289984at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="270" mass="28677" checksum="56AECEB220D7EF23" modified="2013-05-29" version="1">MSATVYLISGANRGIGLGMVAQLAARDNVLVVAGVRRLDTGVSELHALQARYPGKIRILKLLSTDKPNNEAAMAEIKKDVGRLDVVIANAGICSEFAPTLELSADAIREHHEVNVLGPLILFQCAYPLLSTTASAPKFVVISAGMGSFAIGPSILANMTAYGMSKAAVNWVAAKLHYEHPELGVFSESRRRDQSDADKEAQVTLAIHPGVVDTDMATTAINNEPLLIANAQVITVEECKGYVDIPILTIYGNTASRVIGSSDGLTHSGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBY2</accession>
    <name>M5GBY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-dependent phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_87804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630481.1">
        <property type="nucleotide sequence ID" value="XM_040776826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBY2"/>
    <dbReference type="STRING" id="1858805.M5GBY2"/>
    <dbReference type="GeneID" id="63691888"/>
    <dbReference type="HOGENOM" id="CLU_398546_0_0_1"/>
    <dbReference type="OMA" id="AKPNALM"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="300"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="674" mass="75606" checksum="031DBBF89D588D4D" modified="2013-05-29" version="1">MLSSRSQKTAFSKVPIALRRLIVPFSVLVCFSFLLTFLFYLHRPRGLQPIQNIRFGWQAWDAVSYAPQPDRPASNGSGDTVKPPPTQGKHWWEIPEVSDGTIPQTLPLDIWDPLLPHKTGLTELAIESCIFSPVTMEFCNPYSSPAADASKGKWVRVERDLNWKTGLWYLVGSCNLYYRRTRRLNVPLITDLVLLPADICPNTTSTEDATWHRVARSIRNGVWPTQSDFLWYELGGQKDIITEIDVLWGEGPAWLGFEKLQPAIVERNSKVDSVWLTYRRGVTPAQKAPPLHFHDDGTFTILQIADLHYSVSIGKCRDTDREPCVEGDMITADFLARVLDAERPDMVVFSGDQLNGQGTSWDSKSVIAKFAQQVIDRQIPWAAIFGNHDDETDLNRLSEMRLYQAMPYCLASPGPSTVDGVGNYVLKVRSGDPSATHLLTLYFVDSGGYARTGYNPFAKLQYDWIKPSQSEWLLQESAKIRPIERPFTPDGASDLGHPWTRDTGMRRFSKKEGVVLHGRKERTLAKPNAMMWFHIPLQESFADPDMDANWNPLVIGQQLEDSGASTHNGNFFEDGILLAAESDAGGHEIKVVGHGHDHITDKCARVKGVWFCFGGGGSFSGYGKVGFDRRLRVYKISDYGETIRTYKHTEHDKIIDDVILVGKGAIDVGAHIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC42</accession>
    <name>M5GC42_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_19375</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632944.1">
        <property type="nucleotide sequence ID" value="XM_040771480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC42"/>
    <dbReference type="STRING" id="1858805.M5GC42"/>
    <dbReference type="GeneID" id="63686542"/>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_1"/>
    <dbReference type="OMA" id="VRPCRYY"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="44"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU06050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="40532" checksum="34FEC6729993BF9F" modified="2013-05-29" version="1">MLSSRTFTTALRSSRSTLARTYATTSNSPTAKFEGRKNAGGKYVVTLIPGDGIGPEISESVKQIYTAAKVPIEWEEVSVEPILKDGKTAIPDAAIESVKRNTVALKGPLATPIGKGHVSLNLTLRRTFNLFANVRPCVSVQGYKTLYDDVNTVLIRENTEGEYSGIEHEIVDGVVQSIKLITYPASERVARYAFHYAQANGRKHVTAVHKANIMKMSDGMFLNACRQVAKEYPEIKYDEDLLDRVCLQVVQNPKPYSERVMVMPNLYGDILSDMCAGLIGGLGLTPSGNIGRDASIFEAVHGSAPDIAGKGLANPTALLLSSLMMLRHMELYDFAEKIEKAALGTIAEGKTITGDLGGKSSTKEYTAAIIAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC83</accession>
    <name>M5GC83_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uracil permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_116728</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628540.1">
        <property type="nucleotide sequence ID" value="XM_040770252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC83"/>
    <dbReference type="GeneID" id="63685314"/>
    <dbReference type="HOGENOM" id="CLU_021555_2_0_1"/>
    <dbReference type="OMA" id="SAVMWTH"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU01643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65935" checksum="74BA660E429EF763" modified="2013-05-29" version="1">MVNLNPIPPVNRWFSRLGHAFSSKEAFNEFIHTEGNADGKHSWTNEDLRPSSIAQCNWHWWNFCLFWLGMGFGNWTLGSSIVGAGLTWYEAMFVVIIASVVAGLCMAFNSRAASNYHVGYPVLLRTCFGMYGHYWPVLARGCCALLWVSVLNYQGGAYVSTMIHCIVGDAWLNLPVQFPDSVGTSVQRFLGFLIFWAIELPFCSLRPYQLKWLYNFKAWTLGPGVIGLLIYCLVQSKGKLASDAALAGVTLSKGGALGWLFVSNVNSAMGNWSTFIANMPDFSRYATSPKATMWTHILFVPIPAALGGIIGIFGTSALQQAWGVTLWNQWDVMDAILEHQWSGGIRFFVFLESFCAALFLFGAILGANLLPFASDATALFPTWFNLTRGMWFCCIISLALMPWKILASANGFLAFLGGYGIFMGPTASIMIMDYWVVRRGNIRIWDAYTSKPGSTYMYFHGFNLNAVIAYISGMIIPFVGFVGTFGIPVPIGATYLDDFGWYISSIVAGALYVLLCKIRPLSNVDPDMPWEKLAHEFKEERERDIVEDTLEANVDESLNDDVVEKVMEEEQEKGLATSVNVAEVRGTYHHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCJ0</accession>
    <name>M5GCJ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_22191</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628700.1">
        <property type="nucleotide sequence ID" value="XM_040772721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCJ0"/>
    <dbReference type="STRING" id="1858805.M5GCJ0"/>
    <dbReference type="GeneID" id="63687783"/>
    <dbReference type="HOGENOM" id="CLU_013783_4_0_1"/>
    <dbReference type="OMA" id="TCPWITS"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase S53" evidence="12">
        <location>
            <begin position="225"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="553"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="595"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU01803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="635" mass="68097" checksum="6E02A86B1DFE65EF" modified="2013-05-29" version="1">MLALLLIIPLALALPKSHESRHSHPKGWRPHTAPSPSHPLPLRIALTQSNLQLGASHLEVISNPDSPEYGHHWTPEKVAEFFAPSTESVSAVIAWLIEGGVEESRLELSKSKGWLSVHNATVQEAERLLSTTYSFYTHVSGASHLACSDYSLPPSVSPHVDFITPTIHYDFQLPPPSKRGLKREKRAKGMPPAAQLGLPDSASLPKMDLGGLFTIFDQLTHCADQITPDCLRAMYGIPPAGIRLSTSKNSLGVLEFAPQAYLPADLDIWFRKFLPWAVGSRPQFAGIDGGNLDPRSVGLQYNGESDLDLEYTMGFVWPLKPVLYQIGDSYLSGSFNNFLDAIDASYCTYLGGDDPTQDSIYPDTDNPDGYQGTNQCGAFQATKVMSVSYYTCVANVLPVTPMLTPSQYMKLGLQGVTLLFSTGDSGVASGYGVCSEDGQYSSTGTRFVPSFPATCPYVTGVGATQLPEGGSVFSKEVAVESKVYSSGGFSDIFALPSYQSKAVQSYYAKYAPPYTAAQYNNSQAVRGFPDISANGLNYVVAASGNFTLGSGTSAATPVVASIFTLINDERLAIGKGPVGFVNPALYANPWMLNDIISGNNPGCGTDGFAAVPGWDPVTGLGTPNYPAMLAYFLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD03</accession>
    <name>M5GD03_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631051.1">
        <property type="nucleotide sequence ID" value="XM_040772081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD03"/>
    <dbReference type="STRING" id="1858805.M5GD03"/>
    <dbReference type="GeneID" id="63687143"/>
    <dbReference type="HOGENOM" id="CLU_012356_0_0_1"/>
    <dbReference type="OMA" id="HYAFTEV"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="170"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="537"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="761" mass="81090" checksum="52162AC387B04C58" modified="2013-05-29" version="1">MIPMHSSIEISMPPTLFIRGAGGDFEPCLLMGEVILNLAEATNIREITAHLSGKAKIHYNDNASTSSRSHSDSVSILEHEWSFLPGDRRHMHTIKAGRHIFPFQMEFEGNAPASLRTMGGNASISYKIRANAIRGAFATNFTDVKSFNVVRTFTNEALEYTQTLELENTWPGKVMYSIMIPHRAHAAGTEVPVSVKFTPLTKGVQVKTITTEIKEYATLTTKSGPVSSTRTVTTAKHEFQGGHAVDITPRSILPRTATAPIPLQAAAGPRTSRSTASLPGLAQQALDAAEAAAFPPPFPGLSIHPALPVTETPPNGMVLTASPSLENTPNGINGANGVNGYSGVNGTYGHQEENMDLGAGDGEIDTTFKVLIPAWVTPTHSIKPVQISHKIKWCCMLSNLDGHTSELRCALPIHVLSSLCAEEAWNATSNTRNLLFGNAEQEEPVIELPSYPEHIRDRIANAALESTIVAPISASAYTSPATSPRLGPMPLPDVGHEPGVRFTESHTPSRSSIAEESYFPTGTSFADSELLSSLGTAFSGSSASSSHTGSHVHTPVDSRNSSRPNSRPSSRVGSRASSPEPHDRGPGPSDSTTTLGSDSTTRGGGGLFHLPISIKPLTSFNPKGKSRATTPPDGSAPGPSPTTTRRRNAGRASTSRAPSPPPHHHLDPLSQVPHYDIASRGFLGGGIVPLTAQIGLPSYDEAERLERSRSENSLTDLVRRVEHASLTNRLNAIANGDSGADRHRHHSNTLGALQMNAPRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD07</accession>
    <name>M5GD07_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628975.1">
        <property type="nucleotide sequence ID" value="XM_040771111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD07"/>
    <dbReference type="GeneID" id="63686173"/>
    <dbReference type="HOGENOM" id="CLU_1602663_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067771" evidence="1">
        <location>
            <begin position="21"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="166" mass="19075" checksum="C9ADA7553E5B6138" modified="2013-05-29" version="1">MAQCLKLLFCTLFRWMDLSTWRIDLLLMLLNGFQKQEESWLCKAFPQQGSWLPAVWDKEGPHKLNAIIPMTLKMESTEDLAAAPLASKTESKGSGMGDCGSELRKEQLAELFNLLVEKMEAYMFQLSLVRDAYALQEWEIARASSSMDLCRPIMVMHQLWAYMDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD22</accession>
    <name>M5GD22_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_66155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629000.1">
        <property type="nucleotide sequence ID" value="XM_040775806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD22"/>
    <dbReference type="STRING" id="1858805.M5GD22"/>
    <dbReference type="GeneID" id="63690868"/>
    <dbReference type="HOGENOM" id="CLU_033458_0_1_1"/>
    <dbReference type="OMA" id="DVNEHQR"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="299" mass="33312" checksum="8C681AEF21F1E2FB" modified="2013-05-29" version="1">MRYYRSKYPEVDDLVMVQVRSIAEMGAYVNLLEYDNIEGMILLSELSRRRIRSIQKLIRVGRNEVVVVLRVDKEKGYIDLSKRRVSAEDVLKCEERFNKSKTVHSIMRNVGEKLHVDLELLYEQIVWPLGDKYGHPYDAFKLAVTEGDAVFEGISAPPSTISEVRANIGRRLTPQPVKIRADIEVTCFGYDGIDAIKCALKAGETLSTPEIPIKVKLVAPPLYVLLTNSTDKLGGVEALEKAIDVIGSRITKEGGEINIKMKPKAVSETEDMELAALMAKVGQENAEVSGDEAEESGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA1</accession>
    <name>M5GDA1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_51875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629090.1">
        <property type="nucleotide sequence ID" value="XM_040775065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA1"/>
    <dbReference type="STRING" id="1858805.M5GDA1"/>
    <dbReference type="GeneID" id="63690127"/>
    <dbReference type="HOGENOM" id="CLU_2782736_0_0_1"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="69" mass="8416" checksum="2D33CCA727B6C272" modified="2013-05-29" version="1" fragment="single">LWVDYHTDVTMKWAELFEDMEQSNNLDPDNDHHIWLLHFLFLDTINDDAVSFQNMWNYHPMSFRRSGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDM2</accession>
    <name>M5GDM2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_93125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631536.1">
        <property type="nucleotide sequence ID" value="XM_040777127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDM2"/>
    <dbReference type="STRING" id="1858805.M5GDM2"/>
    <dbReference type="GeneID" id="63692189"/>
    <dbReference type="HOGENOM" id="CLU_053888_2_0_1"/>
    <dbReference type="OMA" id="ISACADC"/>
    <dbReference type="OrthoDB" id="2576311at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067667" description="Mid2 domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="173"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="35383" checksum="A28D23F18C9E6F30" modified="2013-05-29" version="1">MLSVFAITFILITWSPRVVQAQGGTSNATCYPPSWELNDQGENPCLVWAQLLTLCQSGPVNVQPLPNNSYYLAPGDNWQPNDCNCNIVSYNLMEACCWCQPQTTSYTWLNETTWIRGCPTYNPTGVTGVSLADVHIPAWTYEPGNGESWDPSQAQAYEAAISVSSTAAQSTSITTTSSSTSNGGSSTTTSSASSPGSSSGGQTGGSTSSSNTGAIVGGVVGGVVGLALIVLLAIFIFRRNNTTGPGFAGPGDAALGMTGKGSDRPMLQQATSFSTASPMPSGATAALYLLYQPGTTTGMGYDGSAPATSYSSSPPPGVFHGGLPAGQNYGSQLAVGGYSGLPEAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDR0</accession>
    <name>M5GDR0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="30">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="5">2.7.1.36</ecNumber>
            <ecNumber evidence="6">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="27">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="33" type="ORF">DACRYDRAFT_75630</name>
    </gene>
    <organism evidence="33 34">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="33 34" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="33 34">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>L,L-cystathionine + H2O = L-homocysteine + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18121"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29256"/>
            <dbReference type="ChEBI" id="CHEBI:58717"/>
            <dbReference type="EC" id="4.4.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="26">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from L-cystathionine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="25">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="5"/>
    <dbReference type="EC" id="4.4.1.13" evidence="6"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631631.1">
        <property type="nucleotide sequence ID" value="XM_040776146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDR0"/>
    <dbReference type="STRING" id="1858805.M5GDR0"/>
    <dbReference type="GeneID" id="63691208"/>
    <dbReference type="HOGENOM" id="CLU_009484_2_0_1"/>
    <dbReference type="OMA" id="QPYRFST"/>
    <dbReference type="OrthoDB" id="2545919at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000013">
        <property type="entry name" value="Cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000003">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="23 33" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="34" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="22" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="18" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="20" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="32">
        <location>
            <begin position="587"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="31">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00046315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00047517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00047625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00072331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="32">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="33">
        <source>
            <dbReference type="EMBL" id="EJU04737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="34">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="916" mass="98415" checksum="51BA6D9CDBF01FBF" modified="2013-05-29" version="1">MVVAKLDNGPLTPVSEGTPALDSPASGPSARYGKRRPYHFSTQCVTVENPLQKDQYGSSSVPIYQTATFKGMGGEYDYTRSGNPTRSHLEHHIAKISSAAHAFVVSSGMAALDVITRLLKPGDEVIAGDDLYGGTNRLLTYLKNNGGITVHHAHTTDATAVVPYLRAGKTAMVLLESPTNPLLKVVDIASICASVRQLAPDALVVVDNTMMSPYLQRPLEHGADMVYDSGTKYLSGHHDLMAGVVVCDRDDVAQKLAFTINAVGNALSPFDSFLLLRGIKTMAIRMDRQQSSAMRVATYLNNLGFKTFYPGLPNHPGREIHERLANGYGAVLSFVTGDKALSERIVGATRLWGISVSFGAVNSLISMPCLMSHASIDAATRAERGLPEDLIRLCVGIEDPADLLEDLELALLQAGAISSVELPSGERRLTRVHPDDGTGLIGMAVEKISGKLDGVHLKETDPESREWFISAPGKVILFGEHAVVHGVTAIAAAVNLRCFSLTSPRQDGKIGLRLPDLGGYEEEWVVEDLPWEALRALADGEPHGPVLDEQLIAAVTNETLRKEKATKSSQNAAVAFLYLYMMLARDDSKPAFTFTARSNMPISAGLGSSAAYSTCVASALLFLHRRISMPHEPAPSTAAHGMHPGHVHISHGGRVAIPKETADEINAWAFISEKVLHGNPSGIDNSVAVYGGSLAYTRPGFARKAGLDPLHGFKSLRFLLVDSKVPRDTKSLVAGVGKRKAEEPDVINPILDAIQDITEEARRALEDHELPRSTLISGLGALIDENHDHLVSLGVSHPTLEIIRAKTASAPYNLRTKLTGAGGGGCAVTLIPDGFPDETLEQLVAELREEGFDAYATTVGGSGMGVFSPRSGEDAEVISTEGGDEQMRVPLSKQFLDKDKTELAQWVEARGRWLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDW1</accession>
    <name>M5GDW1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629632.1">
        <property type="nucleotide sequence ID" value="XM_040772520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDW1"/>
    <dbReference type="GeneID" id="63687582"/>
    <dbReference type="HOGENOM" id="CLU_013253_8_0_1"/>
    <dbReference type="OMA" id="NEWWTIP"/>
    <dbReference type="OrthoDB" id="15189at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF57">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067675" evidence="4">
        <location>
            <begin position="20"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="56"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="534" mass="57568" checksum="E3B5CA6D599E4C85" modified="2013-05-29" version="1">MPTLATVLSFVTLFAGIHAIRIPFKVVHAHDRPASHGRRDTVNATISIIDSTNSIYLGAVVIGGTNYNVQLDTGSSDLWIQGNPANSKDLGIETSITYAIGSAQGEISTAPVTFAGYNVSNQMYLRVGQNATFSSGLFSTGATGILGLGPSSGSILRGQIGNASADALVDRIFEQDPTTPNFVSFLLERLGDGAPVNGQLTVGDIVPGYEAISSQPQLPVIKLKSILSKDQHWTTYVDGIIGPDNSTISYSSSVPSTPTGKLVTIVDSGFTLPQIPRAMSDAIYGRVQGASFDTQHEWWTVPCNQYLNISVVMGGVTFPVHPLDTISSDFGLKDINGNTVCLGTFQPITTAFSVTNEFDMILGDAFLRNSYTLLNYGDFISNGTTSNTADPYMQLLSITDPVKAMNEFIGARLQTYGPINYSLLPASQQQHSPVPAGETVAHYEADVLRYLPEIIVGCAAVLLLIVGCIIWRCCCTKRQRLARAQKKRGMYSESKADYRQIDEPGSAPMGMTPLYTPDLKSPGKAYYPDPYHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE56</accession>
    <name>M5GE56_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Decapping nuclease</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_114373</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631991.1">
        <property type="nucleotide sequence ID" value="XM_040769810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE56"/>
    <dbReference type="STRING" id="1858805.M5GE56"/>
    <dbReference type="GeneID" id="63684872"/>
    <dbReference type="HOGENOM" id="CLU_024877_1_2_1"/>
    <dbReference type="OMA" id="VVTWRGH"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="7">
        <location>
            <begin position="50"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="410" mass="46321" checksum="5B69B76B5023086C" modified="2013-05-29" version="1">MSVTGSFGSFEVLPLPAEVVISHPAWSSNSPLKPDKSIYSARKPLAALTVPTQIATFSYDANHVLRYDDSSLRYFVEPQKGADLEMEFEQWPGPEEDPGRLDSLLFAYMREVDSGKDLEKPNVMTWRGMMTRIVTALYERRDSWEMNAMLVDGTVYLEDNKGHSYVNETVTGYTRGIKNIPTPQRKLMYTGYAFESYCTADGPNQTVSTQHEPDVNTNMQWCSIVQTSIGSSKLVLGGEVDCVRGAYKGKNGNYVELKTSGAIKNVKDERNFERKALKYWAQSYLLGIPQVVVGFRSSRSPYILETVQTFQTFHLPRLGLNAGWSATACLNWTNAALEYIRERLASEGRAVQEEAKMFRIMFRPGEGLQVLTLADEHALAIQNGDHVERVGFLPKGYWEWVMRRRGTTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ7</accession>
    <name>M5GEQ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_21066</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="5"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630382.1">
        <property type="nucleotide sequence ID" value="XM_040772216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ7"/>
    <dbReference type="STRING" id="1858805.M5GEQ7"/>
    <dbReference type="GeneID" id="63687278"/>
    <dbReference type="HOGENOM" id="CLU_013640_4_3_1"/>
    <dbReference type="OMA" id="IYGTDTR"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003645">
        <property type="entry name" value="PRK05286.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003652">
        <property type="entry name" value="PRK05286.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="99"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU03488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="518" mass="55842" checksum="4B02F9E17C649C0D" modified="2013-05-29" version="1">MLRAALRRPLLSSHIHVRSANTTACSSSSPLSYVYGTLLLAGAGVFAAYYVDSRAAVHKYVAMPLVRACVDGETAHKLAVKMLATGLMPRDVKQDDELLECELWDLPLSNPLGIAAGLDKDAEAVDGLYDLGFGYVEVGSVTPEPQPGNPQPRFFRLPADRAIINRYGFNSAGHALVLLRLRTRLRNWPEVANHAQRQGRVLAVNLGKNKSSSPDSIDDYLMGVRAFGSVADVLVVNVSSPNTPGLRSLQARGMLEELLSEVVRERDALPLMGEKPRVVVKLAPDLTKAEIEDVAAAVRATKVDGVIMGNTTVQRPDGLKSPQTLVQETGGLSGQPLKPITIEAFKTLRSLLPASIPLIACGGISSGADALEYAKLGAATIQLYTAFGYDGVGTPREIKDELTELLRKEGKSWREVSREAVAQLAWKDDAESAMERLKQEAENALENLKEISTQIALGDDLAPNWIDPVLENAPPPTIPTPEPPTSVPANEQSPNVVDVLVITPDSTSKEEMDNKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5GES1</accession>
    <name>M5GES1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Guf1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_86648</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632531.1">
        <property type="nucleotide sequence ID" value="XM_040776780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GES1"/>
    <dbReference type="STRING" id="1858805.M5GES1"/>
    <dbReference type="GeneID" id="63691842"/>
    <dbReference type="HOGENOM" id="CLU_009995_3_3_1"/>
    <dbReference type="OMA" id="QVKCDEN"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067719" evidence="10">
        <location>
            <begin position="17"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="73"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="606" mass="67197" checksum="E4248BDD219B215F" modified="2013-05-29" version="1">MLFCTALILPVCDARGQGGMSDRTGTVAKISGANQQMLDKLKVERERGITVKAQTVSMLHRQNDKTFLLNLIDTPGHVDFSWEVARSLAACQGALLLIDASQGVQAQTISVGMLALEKNITIIPVLNKIDLPAADPDRVAAQIESTFGIGADEILTASAKTGVGVDKILRAIVDRIPPPTGDVDAELKALLFDSSYDRYRGVISLLSIQSGRIRKGEKIFLHHTQKKYDVVDIGVLHPEETPTGMLQAGQVGYLACNMKNSNEAQIGDTVFRVGESKHDPLPGFQPTKAMVFAGVYPIDSNDFPKLEESIKRLTLTDRSVTIQRESSTALGQGCRLGFLGTLHMDVFRQRLEDEYDQQILITYPTVPFKIIDNKGKEVIISNPSDFPDPADFSGKIQEVQEPMVKATIILPHEYLGGMMELCSNHRAENIEHSYLDTSGDQPRVLMTTRMPLAEIVTDFFDLLKKTTSGFASFDYEDIGYQRSDMVRINFLLNGRPIDSLSIVVHRSNALHVGRVWTKKLREVVPKQQFEVAIQAAIGKQVLARETLSAFRKDVTAGLYGGHYERKLKVLEKQKAGKKLMKRIGNIELPQEAFYDMLRTNKPSNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF83</accession>
    <name>M5GF83_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_45381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632936.1">
        <property type="nucleotide sequence ID" value="XM_040774641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF83"/>
    <dbReference type="STRING" id="1858805.M5GF83"/>
    <dbReference type="GeneID" id="63689703"/>
    <dbReference type="HOGENOM" id="CLU_046155_0_0_1"/>
    <dbReference type="OMA" id="QIEYIRY"/>
    <dbReference type="OrthoDB" id="5953249at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="1">
        <location>
            <begin position="162"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="416" mass="47592" checksum="ACC4EC4912F2D493" modified="2013-05-29" version="1">MIAVHGFYRYTDIQFEWYKSIPSERGRGGLRAFLNAEALVHPDNPWHAGKQGVELYLLTIPNGEQRLCFSSKQLEYMRYWLQAAKAIDKLEDIPLPSSEYLILESQVKSVSPVTYRTPKDLKSAMRDLSKFNKRVKTSPGGLTDQRTMFERVRAAFQTKKGVWAAIDFESFEYDHKSITEFGYSMLSWDKKGKEVREDGHWCVQENMHKLNGMYVKENRRGFKFGTSEIILDAEFRKRVHNFIYTHGLPGPLYLIVHGGAGDRVYLNLCNVPLLSIAHDLPGTTPTPRGKNAEPLKEGELPNMYTLDTQELFKALEGNHKIARGLERMCQLMRLPDVNQIGGWHNAGNDAHWTLEALIAMASGEPLDKQRELRWPDKVAPPLAPGALGPTETKTNRLAVQWGEEDEEDWDWEEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFC3</accession>
    <name>M5GFC3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_63623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630932.1">
        <property type="nucleotide sequence ID" value="XM_040775737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFC3"/>
    <dbReference type="STRING" id="1858805.M5GFC3"/>
    <dbReference type="GeneID" id="63690799"/>
    <dbReference type="HOGENOM" id="CLU_1028768_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="27962" checksum="C0DB739776B3BD4C" modified="2013-05-29" version="1" fragment="single">AKYNVTTEFPQLGLHAAAVSGNIGLVRYALANGQPVNSVQHGILPLHAACTSGNADVVRELLAAGADVNAPRLPRRYSNDRQTPALGVAGSTPLHFAAASGHEGIIRLLLEVGGDPLRGDKNGVTPIEVAESNGYVDAATLLRLAAAGALIADHSGDPLAGPSSGAGRDPKLQIKRSLDNLLHIRSKNHSPGIVGAPVPRRSTSPGEAPRPPHSPLPPLPLAHISENQPESDGVPSPSTASTISAPGSSIPVRSKPPTTVRKIVHRRPRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFH2</accession>
    <name>M5GFH2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication regulator Sld3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633181.1">
        <property type="nucleotide sequence ID" value="XM_040767729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFH2"/>
    <dbReference type="STRING" id="1858805.M5GFH2"/>
    <dbReference type="GeneID" id="63682791"/>
    <dbReference type="HOGENOM" id="CLU_612520_0_0_1"/>
    <dbReference type="OMA" id="EPLFRTR"/>
    <dbReference type="OrthoDB" id="3003917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="47980" checksum="E7052D7395A28563" modified="2013-05-29" version="1">MSLLDLSCPLAWPSTSTSTDYPLRQRTGESPRETVRRLYWETLWLPEELVALQSVVPALRRLPGGVLVDHLGEVFLPLDGIERKYRVGMPFLLSAQTGAGAGGEAEAEAHELGQGEGEGEEVRMMRFVYKLRERAGVGGGGVHEGGGEGDGEELEEDRERDKREWFDQLERREVQLQLLLRLLQVTLPPARSPRKRKRPSPSHAHARTPVEEIDILSDRLAIWHALGSVLRPPPGPGSTQAEAGERERDWVTAWAEDVLGPLFDGTGAEGLVRGFREKLDPTISPPSSPVSSSGEVVLPLPVPGALDPDTAASRSGSFTSVNLGAGGAGVGVGTGTAAAAAAGYRRSMSVSSTQSSRSVISVSGTRTGVNNSKNWAGKEVRMGRRAIGGARPRQASLPPAPPPPQPARPFRRAESQMLVMSTPVKKPIPRPEPSSADEVMETPQKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFL4</accession>
    <name>M5GFL4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_63869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631102.1">
        <property type="nucleotide sequence ID" value="XM_040775743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFL4"/>
    <dbReference type="STRING" id="1858805.M5GFL4"/>
    <dbReference type="GeneID" id="63690805"/>
    <dbReference type="HOGENOM" id="CLU_008637_1_0_1"/>
    <dbReference type="OMA" id="KWCAVCE"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF83">
        <property type="entry name" value="TIP ELONGATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="224"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="532"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="776" mass="84449" checksum="97B21021638C1DFF" modified="2013-05-29" version="1" fragment="single">MSGIPTANRAPRVSGLPLPGRGTGIPMPGRPRSSVSGGSRPSLSKDDDDTIMVSSLAAAVKARNPSDYTNGNLAHAEPALERTPAPRKSIGPRPSMLTASTLRPPRPPSSASQASYTSTRLQIPDAESPNSFQTAYSTPLQTPAIGSRARTPSTTGQPLRSAPSAYPSQRRPESRQSIGTTARSTSRLGQTWDRSASRTGRPFEVGDRVRLDNKGWEGTLQYLGEVHFRDGIWAGVELLPGFAGKGKNDGSVDGRRYFTCAPNMGVFILADKLSVPAPTYARPPSSASVTSRAGRVTPFNEPPTPEPETPSGFRSRVQAAAAASRVSAGSRASKFLGMTAQQLREAGLADLARQPESIPESPMRSPNRPPSTPKSSGRQSFGLPTPRARQSLGMGGPTPKAKPRTADLSVPMSPPLTLPALSAASTSANTSLQEEEITTPEERHLESGRRAFQNRVAKLMTDDLGVGRSPGQSTPPGSAAAFMDDSPLALRSSVRLPDRIDMLEQENKRLRADAARSSAPSPTKSAASQALIADLQHKLDTSEDALSQVRAKLQEMEGKVQEQVALREAEKEQAADVLSAADERVDEAEKKAAELLSEMDTFKKRMSEVEKERDEKIEHVQELERRVELLVQQANEEREDLLLQVEELRTAGQETIAFYEEHKSAHEADRYELEQNIQKLEEELRKVSETGVPAAAAQQAETVTQIDNEALREQVAHYQSRISKLEDQLEDIQADRLKQEDAYRARIQKAKDQEVNARKELEKIGQDIEEVKKAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFP2</accession>
    <name>M5GFP2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_114641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631182.1">
        <property type="nucleotide sequence ID" value="XM_040769855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFP2"/>
    <dbReference type="GeneID" id="63684917"/>
    <dbReference type="HOGENOM" id="CLU_062280_1_0_1"/>
    <dbReference type="OMA" id="IPKYDMP"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28535" checksum="859734417AE43277" modified="2013-05-29" version="1">MPPSDSISMSAGRRMPTRTRLVFRRIMRSQKFVLPNNYHLPIRLRPWFVIFTLVDMIFLAFLGFTNVVHDVPVNDKVMHFVCLGLATGLVYFIFDVEEDARRIWIWRNAGLFITGFLCFVLGGIVSEFVQGLLPYKTFQLGDIAANLLGSSLGLYLSWNLERYYRHRREIERLYQPLDVLEEPTDDEGDDTLPSFYTRQQPRAVTSLGVQRSRLADVWDEREEVFHLVDGEEDEAEPPKAGTAGKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFP9</accession>
    <name>M5GFP9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631202.1">
        <property type="nucleotide sequence ID" value="XM_040768083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFP9"/>
    <dbReference type="STRING" id="1858805.M5GFP9"/>
    <dbReference type="GeneID" id="63683145"/>
    <dbReference type="HOGENOM" id="CLU_408267_0_0_1"/>
    <dbReference type="OrthoDB" id="5570013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="73284" checksum="D0D938ED61C8441C" modified="2013-05-29" version="1">MIVNDQHQQPDKRSLLDENDTDSVMSKQSTVEDGLPVYAPVDPNSEMKGKETPAPQSNRGRKIKRAIKFCLCALLAYHLYHFVHHRFDGPPRFGFWHGNDHDEMTDSKDVTDEWVNGRYNFAHMDYNLATAEDTNVDIWTMDEVFPVPPDHPDMPHPPEMPDNPDMPPMPPHSPHMPDEPDHPAPPRHPSPPHHPPPPRHHPPPHPPHHHVTVECLSTEGESTALTMQLPFTPSDDGYLPAGAVVDLGNAGLDWTEPVSFNLSTSLRRLVVASHGPVAGSVHLHTDSSLSDTVTYNVTVSDPSVVKICKLLHEDVFFGVAVVAPHERVHPVPRAKIDVWFPSEADINAFTSHTGVFHHDVDDLSGVQFGKFQLGASNAALHVDTVNAKVAVLKTVNAAIDVGTVSGKLVVLTTNNGRITGVVPNATAVIAATKNAPITLNATVWSTADGETSVPESYHAVGCHQHKEEKANTWASWFTREARRERRARRKARKAVRKAGKHWHGHGHGHAAVAEDEEPHDPHGPHGPHHKGDGKGVLVATSTNGHIDVHAWLKSNTTGVFSVVAKSSNTQVEVGVLDQPVNSTLSLTATSTNGRIGVGLHPAFEGEFIARTTNGKSELIETPNVNDPAGLHRVRHITVSRFANILTGSAFWGEKKKRGSAVLSTTNAGVQLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD4</accession>
    <name>M5GGD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_19845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632187.1">
        <property type="nucleotide sequence ID" value="XM_040771682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD4"/>
    <dbReference type="STRING" id="1858805.M5GGD4"/>
    <dbReference type="GeneID" id="63686744"/>
    <dbReference type="HOGENOM" id="CLU_061023_0_0_1"/>
    <dbReference type="OMA" id="DAPFNPY"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044839">
        <property type="entry name" value="NDR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234:SF2">
        <property type="entry name" value="OS05G0199100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33783" checksum="4BE05BB651D4856B" modified="2013-05-29" version="1">MAYNDPYAAPNQGYNMNYVGQPQYPPQASNQPNYNDAQEFNPYEHQPRFPTYDQQPYTDNPGGQAGYTDYSRPPYDREKKFAEARMSVGPPPKDTGMLRIWRQHGRGKQWTRGGGLRSCCRFFGCFLLSFIFILLAVILSLAVFIRPPDVQFNGVSTPANGQTFQQISASSFAVNLDLNIAVRNPNFFGVDFNSITAKIFFPGFTPQLGGGNLTNVQFGSNTATTLAFPITLNYSTTADPSLTLLTGIASSCGYNGAQQSNINVDFSITLALKILFAQISPTISSSIGFACPLTQSEVQGVIGQILGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGG5</accession>
    <name>M5GGG5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_74661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632342.1">
        <property type="nucleotide sequence ID" value="XM_040776078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGG5"/>
    <dbReference type="STRING" id="1858805.M5GGG5"/>
    <dbReference type="GeneID" id="63691140"/>
    <dbReference type="HOGENOM" id="CLU_067602_0_0_1"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000011">
        <property type="entry name" value="Cdp-diacylglycerol-inositol 3-phosphatidyltransferase pis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34673" checksum="FD44D080B523F475" modified="2013-05-29" version="1">MSETDPLIRPRGADAQARSRSRLAELRTQSVADTGLVDAKLAVDLATHEVRENVYLFVPNLIGYTRILLAALSLHFMPYHPRYCTVLYCLSCLLDAFDGMAARALNQSTKFGAVLDMVTDRCTTACLLCFLSSAYPSFATVFQFLITLDFSSHYMHMYSSLTTGSKSHKLVTSDVSWVLSVYYTSQTVLFICCAGNELFFVALYLMHFDHTAVLNASSPKPVIAYLSTQVINLLTSGGPWGVYALSYLELVTWAAVMALAFFPIAALKNFINAVQWWKASKILVGVDLVERARQRQREARGENGSAGVLAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGG7</accession>
    <name>M5GGG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CoA-dependent acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_46425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632352.1">
        <property type="nucleotide sequence ID" value="XM_040774702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGG7"/>
    <dbReference type="STRING" id="1858805.M5GGG7"/>
    <dbReference type="GeneID" id="63689764"/>
    <dbReference type="HOGENOM" id="CLU_016660_0_0_1"/>
    <dbReference type="OMA" id="LICAMHF"/>
    <dbReference type="OrthoDB" id="3355480at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56608" checksum="98BD4488214C6CB5" modified="2013-05-29" version="1">MLPTPPQTPTRLPGTVWQRKLGDTELSYFLPSRTEGVNDMYLCIDFTAPRDLVTDERVLAIWAILRTKHPLLAAEVCMQEGEYDSASFRYVAAQDAHEELARARENLRISVQTKEEVILDYLNGPRLLSKEQPAYLLFGQRDLEQAEFHFCLCTTHYLGDGMALHKTANEFFSLLGEGMCDAELFKLLDHEWTERYSTTEDHRDSPIPQPLEEKLPPLPAQSFARYAARVDYENLQRKTIGGHVMPRKKHGPRRTTVPTVPFSAEETGRALKKCKKNGVTISHAIFALCNMVWLGIKPAGGEDLPTMMYAAANLRSYFSSIEESHFYLAVTYFNIMLPSFIPRDLTPTQTLWLRSQSVKRQMNAVVGSKMYVSRARITASQRASQAKTWAAEDDARDAGESLPPSPPPTRPAHAPPKVPSNALIGLSMLGNLDAIYAHKAFPDLQLHGLTTGSRQRGGAMLLFAYTFAGKLWLSLGYDENGFERVIVQKFWQGLLDSVRENLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGP2</accession>
    <name>M5GGP2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="7">PPIase</shortName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_20195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632727.1">
        <property type="nucleotide sequence ID" value="XM_040771842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGP2"/>
    <dbReference type="STRING" id="1858805.M5GGP2"/>
    <dbReference type="GeneID" id="63686904"/>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OMA" id="TWLTGKH"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="13"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="18663" checksum="88DB85C0FC996299" modified="2013-05-29" version="1">MAGAALRNMANVFFDITIASRPAGRVVFKLRDEVVPITARNFRELATGQNGYGFKGSAFHRVIPGFMAQGGDFTRGDGRGGYSIYGEKFKDENFKDRHVKPGLLSMANSGVNTNGSQFFITTAPCPWLDGKHVVFGEVVSGMDLVRTIESQGSDSGDPKSKIVIADCGVVNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGY0</accession>
    <name>M5GGY0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_45093</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633167.1">
        <property type="nucleotide sequence ID" value="XM_040774624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGY0"/>
    <dbReference type="STRING" id="1858805.M5GGY0"/>
    <dbReference type="GeneID" id="63689686"/>
    <dbReference type="HOGENOM" id="CLU_076902_10_1_1"/>
    <dbReference type="OMA" id="MSKAQPP"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000023">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU06273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="77" mass="8584" checksum="67BF4913B961D311" modified="2013-05-29" version="1">MSRASQPELKKFMDKRLFVYIQGGRRVSGVLRGYDIFLNLVVDDAVEESGTSGKKHIGQVVIRGNSVTSMEVLEAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP14</accession>
    <name>M5FP14_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623606.1">
        <property type="nucleotide sequence ID" value="XM_040770894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP14"/>
    <dbReference type="GeneID" id="63685956"/>
    <dbReference type="HOGENOM" id="CLU_696432_0_0_1"/>
    <dbReference type="OrthoDB" id="3171382at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="402" mass="45333" checksum="8AA62CD9BFD2F6C9" modified="2013-05-29" version="1">MSSSSSSTSDPKGKRQRPTYPPGTAMPPPEPGGVTTSWAPPPHHVATGVNVPQWVDERCLSYCTQRSGNRTFQGEPTCHVLCWRKIYEHEQRLLDAASLPGQIGINSPGTSPQVDKWKAERARLRSLTRRFAPEREKQWKSAASERKASLAERPASPPPVEGRTREGGDELRGPEKTLQLETDTSASTSANFISGSFSPFPPPPNNIWSFLRGHYIFYGRGPDRVIARTRTMGHIGHPNNWYLTAKELEKDGESVGAILESSLKEQAKLQQLVEAPGAVGMKHLHAEENWKKAQKKERRKQTDYIVLISLEHLPFAMYSSAVSTLERVTGPLGAFFTKYQESFTSGQQVRTMRRIWSTVKDPEYGPMGMFKRATESWERLRKEEIDKSMREKGKERSSREKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPE5</accession>
    <name>M5FPE5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_112341</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623911.1">
        <property type="nucleotide sequence ID" value="XM_040769394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPE5"/>
    <dbReference type="GeneID" id="63684456"/>
    <dbReference type="HOGENOM" id="CLU_004965_3_0_1"/>
    <dbReference type="OMA" id="YFWIVFA"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="685"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="721"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="761" mass="84771" checksum="B1846CD582976B33" modified="2013-05-29" version="1">MGSPEVTEMPLMKSSTQDELHSPLEKTTSQLSGRIKDDGTYDAPKKAYSLAKVSTKQVDDIENTNSESETPPEETTEVVKNADDIAALIISAEDDPDLPVLTFRFWVLGCGLSAFGAVLSEIYYWKPQNASVSPLFQLIIAYVLGNAMHYTMPTTGFWRYVNPGPFNIKEHTSITIMASTASSTATSIGIVGTLDLFYGVTLSPAAAIFQSWASQLIGYGFAGILRRLLVWPTYALYPGTLPEIALLQSMHFGGLLNRKKMRYFWIVCIAIFCYEIIPTWMFPLITAFSIICLVDEGRSTFTRNLFGAGSSNEGLGLFSFGFDWVLISQAYPLYWPLQTQVSAWIGMALCYIVMMACYYGDVFQGYSRGLPFMSTGLFSGNGSSYDQTVILDANNQLDPVKFAEIGPPYMTTTYAVSLLHCRDLKNAFGKFRFMQGADDIEDIHYEKMKIYKEVPQWWYALIFFASLGVAIGTAYGHVDTLPWWSVIVFTIIAFILAVILGVIAAVTGFSVPTSSFVQVIAAYIHPQQPIQNMYAKLYGYNTGYQTLALLSDLKLGQYAKIPPRATFVAQCAGTVLGAVLDYILYKSMVDAHRADLQNPIGTRLWSGWVAQELNSAAITWGALSAELYNPGKLYFQIPMGLLYGFLAPIPLYILHCFFPKQQVWSYLNMPVLLTYLGWLPYSVNGMWWTSLVIGLASQWWVRLKYPRWYKKYNSLDGGTSIIYFILNFAVFGAGGQGVNFPIWWGNPDPNVLSVDHCAVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPF9</accession>
    <name>M5FPF9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625428.1">
        <property type="nucleotide sequence ID" value="XM_040773728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPF9"/>
    <dbReference type="GeneID" id="63688790"/>
    <dbReference type="HOGENOM" id="CLU_1740472_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="16949" checksum="92CA8C3E3746C3D6" modified="2013-05-29" version="1">MSQHRRFRDSITSSSNSSSLRHIPSSSSSSNNNNNNKTRLSHSPLQGRSLPPQAPPRPLPPLSAQEEVATGERHRLKDRRLILFTPLSLKHRGTTPPRPRHIRPSKSPQMEQAELSQTPVQHRGRSYTVCQHRKTLGSYQEKPLVNTSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPG7</accession>
    <name>M5FPG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Formamidopyrimidine-DNA glycosylase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_91738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623961.1">
        <property type="nucleotide sequence ID" value="XM_040777021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPG7"/>
    <dbReference type="STRING" id="1858805.M5FPG7"/>
    <dbReference type="GeneID" id="63692083"/>
    <dbReference type="HOGENOM" id="CLU_038423_0_1_1"/>
    <dbReference type="OMA" id="EKFPEHW"/>
    <dbReference type="OrthoDB" id="444592at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08972">
        <property type="entry name" value="PF_Nei_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000009">
        <property type="entry name" value="Formamidopyrimidine-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="entry name" value="MutM-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="FPG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="H2TH_FPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993:SF9">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="N-terminal domain of MutM-like DNA repair proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase catalytic" evidence="10">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="324" mass="37049" checksum="BA2FCFD6E76F4069" modified="2013-05-29" version="1">MPELPEAERATRLLQKYLKDGLITAVDTIEDNIVYSDISHEEFAKELTNRTVLNAHRYGKVFWLELDAPTEESRHPVFHLGMTGMIQLQGQEPVWYRVRPKDASAWPPRFMKFIIHVTPPSGPAVHVAFTDARRLGRIRLRSNPCAQPPIIDLGFDPLLSMPSLPTFSSLMLKRNMPIKALLLDQSFSAGVGNWVADEVLFHARIHPETRANELRPEEVKRVWEKVRWVCEVAVGVDSDGSRFPSDWLFRFRWGKGKKSTGKLLLPDGREGTIRWITVGGRTSAYVEEVKEPDVEEEKNAEEELVLQRKVAKVCPMPFQNLDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPM9</accession>
    <name>M5FPM9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_85186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624076.1">
        <property type="nucleotide sequence ID" value="XM_040776720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPM9"/>
    <dbReference type="STRING" id="1858805.M5FPM9"/>
    <dbReference type="GeneID" id="63691782"/>
    <dbReference type="HOGENOM" id="CLU_003896_4_1_1"/>
    <dbReference type="OMA" id="YPRFGEF"/>
    <dbReference type="OrthoDB" id="610608at2759"/>
    <dbReference type="UniPathway" id="UPA00771">
        <property type="reaction ID" value="UER00766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="489" mass="55700" checksum="3890BBE88FE3A66D" modified="2013-05-29" version="1">MADQTTEALYAALECIREDTLHRSLLPPFRKYRKTAWFQNWAETFRCTPQAVFAPRDFDQCKSILELAKREGKRLRAMGARHSPSDLWCTNEWMIRMDRIDRLIVWDSPKNSIVAPAGMTLHTLHRKLGINGLAMRNVGSISDQSIAGVISTATHGTGWDFPVISGDVLSLTILLANGEIVTCSKEVQQDLFLASLCGLGATGLILSVELQLERSFKLQESRERLPFEIVLKSLDLFAPASEHTRIWWNPQADTAMLMLASRSSAPLSPAKSSWFWGTVVGHWYLEFLLWLSLAYPDLTGWIGRFASGLDAKKVVVVDQSWKIFNLDCLFRQYTTEWALPASQAQSALSALRALLATEAKKPHGLRPHFPIEIRWSDADEIWLSPSYGRKTCWVGIVQYKPYGIDVPWRGVFDAFESIMLSHGGRPHWAKLHPLTPEQLGEMYPRFADFKRLLERVDPEGIWRNEYVRRHVFGEWEGQGADVYSKRVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPS5</accession>
    <name>M5FPS5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3 10">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_57190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3 10"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040775422.1"/>
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    <dbReference type="STRING" id="1858805.M5FPS5"/>
    <dbReference type="GeneID" id="63690484"/>
    <dbReference type="HOGENOM" id="CLU_024853_3_0_1"/>
    <dbReference type="OMA" id="RHLFHYG"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NAD(P)HX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)H-hydrate epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="11">
        <location>
            <begin position="11"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="131"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="26609" checksum="BFE20929FD95D027" modified="2013-05-29" version="1">MSMRYLTAHLAQEIDAKLMGEAGAFSLDQLMELAGLAVAQALAASFSIPKYTRVLVCCGPGNQGGDGLVAARHLSHFGYKPTLYMPKTGNKDIYQRLHKQCTNMSIPTLPASADLPASLKSQDLILDAIFGFSFQGPLRAPFSRILPLLRDSGLPMLSVDIPSGWEVERGPVPLQSEEGEDLGAPLDPEVLISLTAPKLGVKGYRGRHWLGGRFVPPAMEREWELNLPEYPGSEQIVQLPTSAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPU6</accession>
    <name>M5FPU6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_59226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPU6"/>
    <dbReference type="GeneID" id="63690608"/>
    <dbReference type="HOGENOM" id="CLU_2800904_0_0_1"/>
    <dbReference type="OrthoDB" id="2676448at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="68" mass="7814" checksum="D5C45B8FA0D4557B" modified="2013-05-29" version="1" fragment="single">EYNKALDSLESLVVQWLFELKKLDLQGTGYKMCCMLGEALQRRSNAIWIALNKYNELAACVHQPIPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ24</accession>
    <name>M5FQ24_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_119189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624386.1">
        <property type="nucleotide sequence ID" value="XM_040770735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ24"/>
    <dbReference type="GeneID" id="63685797"/>
    <dbReference type="HOGENOM" id="CLU_008090_0_0_1"/>
    <dbReference type="OMA" id="HESFIVV"/>
    <dbReference type="OrthoDB" id="2590746at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="593" mass="65787" checksum="771C22B8D16E226D" modified="2013-05-29" version="1">MTTFLSSILPTGLRIPSLPNPIAFLTRQEEEQPPEPQRQPQPDTNVQNQPSEIHPHTDDHVEHAVSDTELHEDLGTRRRRQPNETFIIVRPPPAKNNHPLNLQIQLIPPNLQKQQRRSVELSRDDIQSPVTPDSAGSTLTRRTSIRSDRSASLYSFASSSVTSLSSTSSGRRVIPLYNLSAHNVIQNTVLDAGTDAKVAKFMKKGLEVMQVVYIEPVEFWEHSHHLLDHRGTRLSDNSHITNTESAGDRTPRTSFSHDKYPYPAPPITPRAERLAPPQPEQKKQKRPFGNLFKRRNGSISELSAVQQPPPSPARTETMPTSPSITTSEERLLAPTLGLQPTQGSKMAAHNHNRAISYVWVVRKWLKPTGENWLNKGLNNLRMGGLNQADPMADIELRFEWTKAGDHRQGGRRRSVTEAESATPSARNSIVAPHATSLAPPNLERCPAPSFKRRSVSPRSSAAALHVPPAPTSIETSSTNSQSDPEDDDTPWTCTLHVSPTQAKMRVAALIPAPHHPKLLGQVKIPFPLPDVAVDRGEFLPRVDGVDNVEEAGLLLTAEDIKDIIASTCLWLVVRESFGGIDKKRKGDGWRLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ45</accession>
    <name>M5FQ45_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Four F5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24074</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SERF family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625863.1">
        <property type="nucleotide sequence ID" value="XM_040773532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ45"/>
    <dbReference type="STRING" id="1858805.M5FQ45"/>
    <dbReference type="GeneID" id="63688594"/>
    <dbReference type="HOGENOM" id="CLU_165034_3_0_1"/>
    <dbReference type="OMA" id="HAKKQTE"/>
    <dbReference type="OrthoDB" id="18018at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040211">
        <property type="entry name" value="SERF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13596:SF0">
        <property type="entry name" value="SI:CH211-39K3.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13596">
        <property type="entry name" value="SMALL EDRK-RICH FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="62" mass="6901" checksum="212661622ECE7E63" modified="2013-05-29" version="1">MTRGNQRDRDRERAQKKTGAAKKPKESNTSLQQRKERDAEAMRVKKEAKDKATAETAGGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ84</accession>
    <name>M5FQ84_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_118311</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625918.1">
        <property type="nucleotide sequence ID" value="XM_040770559.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FQ84"/>
    <dbReference type="GeneID" id="63685621"/>
    <dbReference type="HOGENOM" id="CLU_000487_3_0_1"/>
    <dbReference type="OMA" id="KPCMGIV"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.140:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="17">
        <location>
            <begin position="246"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1600"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1600"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1615"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1709"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1745"/>
            <end position="1770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJT99020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1770" mass="196128" checksum="FFE073BBD2B157E8" modified="2013-05-29" version="1">MSMFAQTVTYSAAPVHKVREVQFGIMSPEEIKAYSVAKIEHSEVMDESGYRPRVGGLMDPRMGTIDRNYKCQTCGEGPGDCPGHFGHIELARPVYHAGFLVKVKKILECICVNCGKLKADIGDDTFRVLVKRADNPKRRLQIVWEYCKGKMLCESDDMKEEEEDPEKPQKPSHGGCGHIQPLIRKDGLKLFLVYKKRKGDDDDEDVKLAQPEKRLLTAAEAHSILRKIPTSDLRLMGLSERYARPEWMILSVIPVPPPQVRPSIMSDSLRSEDDLTYKLADILKTSATLRKHDAEGAPAHVVSEIEQLLQFHVATYMDNEIAGQPRAMQKSGRPVKAIRSRLKGKEGRLRGNLMGKRVDFSARTVITGDPNIALDEVGVPRSIAMTLTYPERVTKYNLERLTELVRNGPVEYPGARYIIRDTGERIDLRYKRGDVSLQIGWVVERHLRDGDYVLFNRQPSLHKMSMMSHRVRVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELKEIAWVPRQIVSPQANKPVMGIVQDTLCGIYKMTQRDIFLDWPLVQNILLWVPDWDGTIPHPCIIKPKPMWSGKQIIALVIPQGINLANGNLSIGNPINDDALIIENGEIMMGIFNKGIVGSSAGGLIHVVFRERGPEVTRDMIGGIQTVVNYWLFHNGFSIGIGDTVPDKPTEKSIMTNIETAKEDVRKVVEEAVKGLLKPRPGMTIRESFEASVNGILNQVRDKSGKSAQQSLKRDNNVKTMVTAGSKGSFINISQMSAMVGQQNVEGQRIPFGFKHRTLPHFTKDDFSPESRGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKAMEDVMVAYDGTIRNSLGDVLQWTYGEDGMDAAHVEEQKMSLLTISDAVFQKSFRVDILAGAGAGFSRNALQVGIIDPKKEFDVQKRLDEEFQQLQDDRRLLRTFIFPNGPPKRLVLPVPISRIVQNAKAAFEIDRRRSSDLDPVYIIDEVKALCTRLKVVPGEHALAMRMQQDATLLFQIMLREQLAVRRVIEEHRLQKVAFDFIVGEIEQQFLRARAHAGEMCGVLAAQSIGEPATQMTLNTFHYAGVSSKNVTLGVPRLKEIINVATHLKTPRLKVYLDPNVAISPEASKAVLTELAHATLRTITKSTEIYYDPEPSTTRIEEDRDFVEAFFSIPDEEVEQKMNLQSPWLLRLELDRAQILDKKLEMSYVASKISEAFQSDIFVIWSEDNAEKLIIRCRVINNQSDKDESGNIEEDVFLRKLENTMLNSISLRGVDGISRAFMVQDSKTVLTPEGDYRTDKDDWMLETEGINLKKVLCVEGVDATRTTTNSLLEGFEVLGIEAARAVLLTELREVLEFDGSYVNFRHLALLCDIMTYRGTLMSITRHGINRTDAGALMRCSFEETVEILFEAAAMGEKDDCRGIAQNIMFGQVAPLGTGAFDVYLDMDMLKDVPIDEAITAAEFTMDGGMTPAAGSMTPYDRSPVYEGGFRAEAAAFSPLVMAGADETSQFSYRATLGQSPLGAGLGGASPGYAPTSPAYSPTSPFVPTSPGYTSGATSPFITSPLGAGATSPFYDPRRTAAMATSPTYSPTSPALQMTSPAYTPTSPAYTPTSPNFSPTSPSFSPTSPNPRAATGYSPTSPQYSPTSPQYSPTSPQYTPTSPQYSPTSPHLSPTSPRYSPTSPVHGASTQFSPTSPAMMSPTSPSYSPASPAYSPTSPAYEGAASPARGNQQNGQNTSGYASKQKFQASPSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR28</accession>
    <name>M5FR28_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624202.1">
        <property type="nucleotide sequence ID" value="XM_040769298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR28"/>
    <dbReference type="GeneID" id="63684360"/>
    <dbReference type="HOGENOM" id="CLU_721640_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="383" mass="44344" checksum="6231A4FCA0B01451" modified="2013-05-29" version="1">MYTRLAGWFIGNVLLLANFEERTIHLFQPKEGEQLSRPYFSQQMERFFEAQLHSVEERQVLALRYNDRIVLHHIVVLPDSVGIHPYWSHQYLENEEDTSTYVSAIGVSPSGSLVYVEHHFRSTQNSQLKMVTTSDPSSIKTSVTVIEQCDKLDILRHVDSIHFTSEGHALIGRSESLLWFEVSLFGEFDPKMTVDPLRPIVQSECWKYWRREWDTKHDPNFEKDAISDIDMSEMAIPDEWFVEEDLNAFISDFLAVPDGHRWWLRYGWGVVAPTKLVAVDDNDPFCFEAIISVETSKGIRYIVMDRGSDENDWPLVPSLQATDQLSVESCFQLPLSIPRMDAQKWALDLNAARRELVAGWDRETLYQRAKRDEWGDDVGLIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR51</accession>
    <name>M5FR51_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624247.1">
        <property type="nucleotide sequence ID" value="XM_040769306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR51"/>
    <dbReference type="STRING" id="1858805.M5FR51"/>
    <dbReference type="GeneID" id="63684368"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OMA" id="HCELPEA"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="35523" checksum="88E541904A9EEC7B" modified="2013-05-29" version="1">MSIPPLPLDTTLQGRSVLITGANVGLGFSAALLALQLGASPLYITCRSAEKGNKARDDLLADPVVRKKNPRAIVKVYELEMSKWDGVTSFAEKFLDDRHKAGEGLDIAILNAAMFSIAYEVAPTGNEMLLQVTYLSTALLSLLLLPLLEKSTTSEHTARLTFITSGMHMNTSLKHCPPDDVNYLASLNDKKTFGASDRYGLTKLLVILFLRHLCEKVGTDKVIINNACPGLIQTKLERNLPWVIAPFVQLMKFTAGNSVEKGATCYIAAVASVGPESHGQWYQRMKLTPYSEVVTGTESKKLQQRIWDETVKQLQTVCPGVGTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRB8</accession>
    <name>M5FRB8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Longevity assurance proteins LAG1/LAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_111536</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624387.1">
        <property type="nucleotide sequence ID" value="XM_040769255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRB8"/>
    <dbReference type="STRING" id="1858805.M5FRB8"/>
    <dbReference type="GeneID" id="63684317"/>
    <dbReference type="HOGENOM" id="CLU_028277_2_1_1"/>
    <dbReference type="OMA" id="KLYCLLQ"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="111"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="42045" checksum="C34E93C07BC5EB1D" modified="2013-05-29" version="1">MSFVNDSLPHYPGLADRTRPFFSLSYPVPTPHNTNLLPQWQHYGKGYLDACFVLTWIIFFSVTREVAMSYILTPIARRVLYGTTPTVPTPSNGVGQRPKSHRKREERQRARNITRFSEQGFSLIYYVVYWSFGMYIYVNSPWAPYKLHELWIGYPHTPLPGPVKFYYLTQLAEWCHQLIILNIEARRKDHWQMFSHHIITIGLMIASYMGNLTRIGTMILLLMDFCDWVFPTAKMLRYVGFTTGTDIAFVIFLASWFLTRHLLFITLIYSTYRHAPQHIPLRWSPSNGLYLSHSSWTIFLVLLSILQVLMLIWFWMILAVALRVVTGRGAEDVRSDDEEDSEGGSNGQSGASVQTPAETRKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRF7</accession>
    <name>M5FRF7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625146.1">
        <property type="nucleotide sequence ID" value="XM_040773807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRF7"/>
    <dbReference type="STRING" id="1858805.M5FRF7"/>
    <dbReference type="GeneID" id="63688869"/>
    <dbReference type="HOGENOM" id="CLU_677967_0_0_1"/>
    <dbReference type="OrthoDB" id="3341212at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="46371" checksum="82D03AAA553824BE" modified="2013-05-29" version="1">MNAVEDPDYGILASHIDQRVRSVVLSYPFLWTNIQLEGPLSQAKARAFLQRSQNLPVDIYLRYFSQKDADVLLYVAQINEFRRLFKEIAAASNRWRTLSFDIRDYDIMTYAARAIPHPLPLLEKIILRCRTAPHTPTEEHVFTLFPEGQPPKLKHIDFDAVNARWDRPFVQGLETMRIVRSVQCVPETVEQLCASLRVSPGLKRLQLESLNSVTSGDTIRHVPLEELDILIFWKVNPDVVGRMLEYIQCPNLRVLEIQLTSSRRNMPIIEALGTSMIPLTNLHMLGLGGCDYPPDIIYTVLRRLSTLKAIRVIGGSLPHALLHGLSGKLDFDGTGNMTEWICPQLESLQIKNATNITDNDVCKTVARRYKNRQTQRIRSVWLGGCPHITDEIERKLEHYKTSVQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRN1</accession>
    <name>M5FRN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626738.1">
        <property type="nucleotide sequence ID" value="XM_040770391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRN1"/>
    <dbReference type="GeneID" id="63685453"/>
    <dbReference type="HOGENOM" id="CLU_933915_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="33348" checksum="2966D64AD2CC319A" modified="2013-05-29" version="1">MPDYYPSFCLLVTALRTPTLKILSVVMRDDPPNPGIESSFLAEVGVGWTHITDIVILSLLPTYDQREALLRALNTSMPTIQTLAIVGPLAMHPKVITGLSKLPSLRTLSLCPIDITENKKPGSLSVADLQEELYGLTELPTGDTSRPTVFRSLEKLIISSDLSMCIAVFSAVRSCNRLVNLNLSTDIANMHDLAVLIDAISPLHPDSFRLEHLKLSLTESDGSFDNIPFWRALNGLERLDLRSFTLDCKCESDDRLEVTNDRVDRMISSFSRLQVLDIHTYMSDKNDKKTLQKICRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRS4</accession>
    <name>M5FRS4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_57596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625351.1">
        <property type="nucleotide sequence ID" value="XM_040775455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRS4"/>
    <dbReference type="STRING" id="1858805.M5FRS4"/>
    <dbReference type="GeneID" id="63690517"/>
    <dbReference type="HOGENOM" id="CLU_152072_2_1_1"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="5978" checksum="2D18437E9C383F48" modified="2013-05-29" version="1">MPWLAPLCLWGAAAGTFVTLLMSPVPLFQKDVLLKIPGIKDFFEDTTPISDKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS01</accession>
    <name>M5FS01_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_118787</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625446.1">
        <property type="nucleotide sequence ID" value="XM_040770658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS01"/>
    <dbReference type="STRING" id="1858805.M5FS01"/>
    <dbReference type="GeneID" id="63685720"/>
    <dbReference type="HOGENOM" id="CLU_119276_0_1_1"/>
    <dbReference type="OMA" id="AKMKWMF"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="122" mass="14338" checksum="37EC4F18C5D80595" modified="2013-05-29" version="1">MPRSSKFKDEHPFEKRKAEAERIRQKYPDRIPVICEKEDRSDVPTIDKKKYLVPSDLTVGQFVYVIRKRIKLAPEKAIFIFVNDMNPATSQLMSAVYEEHKDEDNFLYVTYSGENTFGCEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS65</accession>
    <name>M5FS65_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_110543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625536.1">
        <property type="nucleotide sequence ID" value="XM_040769074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS65"/>
    <dbReference type="STRING" id="1858805.M5FS65"/>
    <dbReference type="GeneID" id="63684136"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="OMA" id="GPHHNEE"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="332" mass="36288" checksum="83273A604372F2AA" modified="2013-05-29" version="1">MSLPTRKIGTTSVPIPGYGLMGFSALYGTTASEEEFLPVFKAAYDAGCRMWDTADVYGRKGLHENERLLAKAMKELNIPRNDIFLCTKFGALAGFVGVRGDPEYVHSACAASLEALGTDHIDLYYQHRVDPKTPIEDTVRAMKELQDQGKIKYIGLSECSADTLRRASKVAKIDAVQIEYSLFSTDVETNGILDACKELGVTFVAYSPLGRGFLAGRFKSRGDLSAGDWRLTVPRFSEENFPTNLDLVNKVSSIAHAKGCTPAQLALAWLLAQGPNVFVIPGTTRKEALLDNIGCAKVHLTDGELAEIRKILDQFPVAGTRYNASVMHTVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS66</accession>
    <name>M5FS66_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_24893</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 12">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="12">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="12"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624887.1">
        <property type="nucleotide sequence ID" value="XM_040773902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS66"/>
    <dbReference type="STRING" id="1858805.M5FS66"/>
    <dbReference type="GeneID" id="63688964"/>
    <dbReference type="HOGENOM" id="CLU_055690_0_0_1"/>
    <dbReference type="OMA" id="PPYDFND"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="188"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="279" mass="30022" checksum="8C1744151E6F07C2" modified="2013-05-29" version="1">MALPARAVSLKPFNLASTVRTLPSGVPSVPGINLYAKVYGADHGHDHGHSLSRSDVPPSWASGIRLGGGSKFESRTVMNAPVSRGMHTSTKVPSANPYSVPDWSHYKTESPSMNRAFSYFMVGSMGLLGASAAKATVTDFLATMAASADVLALAKVEVSMSAIPLAKNVIIKWRGKPVFIRHRTAAEIDDARHVDLKSLRDPETDEARTKRPEWLVMLGVCTHLGCVPIGESGDYGGWFCPCHGSHYDISGRARKGPAPLNLEIPPYDFNDAEEKIIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS84</accession>
    <name>M5FS84_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627108.1">
        <property type="nucleotide sequence ID" value="XM_040768775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS84"/>
    <dbReference type="GeneID" id="63683837"/>
    <dbReference type="HOGENOM" id="CLU_1402387_0_0_1"/>
    <dbReference type="OrthoDB" id="10612000at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="22185" checksum="744BAF727648C8A4" modified="2013-05-29" version="1">MNSRHDFLSKAHDHHGAVLVVRLGGIVKFGRHARGKYSRDNLGVDEERSGSRVVDALYDLLPRRNKHKHAPHDSRRSYWSMDKDTRERADRNQTYWLDRGIEPGASWFVLSTVALIAIATVGSAMSLGNPTLDTLEGRSFDEEDHGLERRVKLQKPCNSKYQNCGDKIKSVKKPKDWVIERSLDDKTDVEFDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTA8</accession>
    <name>M5FTA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Kinetochore protein Sos7 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795919">
        <property type="protein sequence ID" value="EJT96486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623384.1">
        <property type="nucleotide sequence ID" value="XM_040769483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTA8"/>
    <dbReference type="STRING" id="1858805.M5FTA8"/>
    <dbReference type="GeneID" id="63684545"/>
    <dbReference type="HOGENOM" id="CLU_062075_0_0_1"/>
    <dbReference type="OMA" id="RIMIEEM"/>
    <dbReference type="OrthoDB" id="18959at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037475">
        <property type="entry name" value="Sos7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048781">
        <property type="entry name" value="Sos7_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329:SF1">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20882">
        <property type="entry name" value="Sos7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Sos7 coiled-coil" evidence="2">
        <location>
            <begin position="71"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="350" mass="38987" checksum="45D42B5969ECDE74" modified="2013-05-29" version="1">MAGTSTMSDMDLNAVRKLAQSYTTHPLHLTALHASYLDRATSDLPTLSDSLISLQPLNPSLLERDVADHKDYFTKIKFKYLEQESKERFLRYILREDPPSLRAAHNMQLEQTNTALKTSLKTSKLALESSSAQVRTLAPQIDALHTQTLADAAESTQLVKEIRDMELELARLRAQHPPESRMTISRATQILDEQVDTLQQLTKELHVRTQALGQKKGALQGKAKELERVELDRIAAEARLGEAKRASEGRDGNVEKLVSWYTNAIAGYKDLMGIVGLSAQTENELRVVYRTPRGDRTLCLIFEPGTGRLGDARVLEEKLDITEAVDLAVAGNDVPGLVRRVLALLRSART</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTD3</accession>
    <name>M5FTD3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625537.1">
        <property type="nucleotide sequence ID" value="XM_040773610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTD3"/>
    <dbReference type="GeneID" id="63688672"/>
    <dbReference type="HOGENOM" id="CLU_2277382_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067293" evidence="1">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11954" checksum="8E9DFEBFB4AE97C2" modified="2013-05-29" version="1">MRSTLLFTAALALLPNLTAAFPLMVQTLPRSGLYKRDDFGEMFPLSPREESEPLFRRRDIYGEVVELSEREETAAAIRSKWSREYEREYERDYWGDVPSAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTV1</accession>
    <name>M5FTV1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_101529</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625782.1">
        <property type="nucleotide sequence ID" value="XM_040767563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTV1"/>
    <dbReference type="STRING" id="1858805.M5FTV1"/>
    <dbReference type="GeneID" id="63682625"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="ARYWGED"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067240" evidence="11">
        <location>
            <begin position="19"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="509" mass="58187" checksum="310702E3DBB022A9" modified="2013-05-29" version="1">MIVAVLLLVSAVALVAITRDIYRKWTSRLPPGPKGSVLVGNLFQVPATFLHRKLHEWSLKHGSLYTIWMGSQAYVVVNSVQVAADIFDRMSGTTSERPMMIKGRQFYVRDLLLQTQGHTLQWRANRRAVHANMNIRAASRFHPMQEHDAAYFALGLIQYPEKKYDKHCHRFATSMISGALYGKRIDHKDDSRLLHKIEEMTQRLMEALMPQNSVVDTLPFLEPVIRRVKWFRKQSDDWHEEATMEGFRLYNAANETDSWGAITTVQDFETNREKYGLSRDDAMWDTLALYMAGQETTHTVMRIFALAMLHNPAVMRTAQRQLDAICENRTPTFEDRPKLPYIEAVALEAARWRAPVPTSVLHAASAEFVYEGYTIPKDTILVDNLWSQTRDASVYPDPEAFNPSRYLDQTTGTLLPPTADTHLSLLAFGHGRRVCPGRDFALNSVFIACAYLLWAFDFSWPVDEHGNEIKCGVDEMVDHAIVVTPRPFDFVLTPRQKDLEERLTVAMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTX2</accession>
    <name>M5FTX2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628018.1">
        <property type="nucleotide sequence ID" value="XM_040768652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTX2"/>
    <dbReference type="GeneID" id="63683714"/>
    <dbReference type="HOGENOM" id="CLU_1970502_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067290" evidence="1">
        <location>
            <begin position="22"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="14154" checksum="936E4B948D8351BE" modified="2013-05-29" version="1">MIFPNLAIQLSVSSAMLLVTACPAPTHYVNDSPALSLQHIPTADLATELYARSYNEEEFEPVLAARHDHIKYEFRRGTPVKTKDGKKHGTVLGPEKKPAYKRVEWKNPEKPGAVEVEDVPAKYLVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTZ7</accession>
    <name>M5FTZ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 14">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="10 14">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_24065</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10 14">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 14">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 14">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="10 14"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625852.1">
        <property type="nucleotide sequence ID" value="XM_040773526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTZ7"/>
    <dbReference type="STRING" id="1858805.M5FTZ7"/>
    <dbReference type="GeneID" id="63688588"/>
    <dbReference type="HOGENOM" id="CLU_024540_4_2_1"/>
    <dbReference type="OMA" id="CVTHVGP"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
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        <location>
            <begin position="181"/>
            <end position="478"/>
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            <position position="185"/>
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        <location>
            <position position="192"/>
        </location>
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        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
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        </ligand>
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        <location>
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            <end position="133"/>
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        <ligand>
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        <location>
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            <end position="189"/>
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        <location>
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        </location>
        <ligand>
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        <location>
            <position position="262"/>
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        <ligand>
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        <location>
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        </location>
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        </ligand>
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        <location>
            <position position="448"/>
        </location>
        <ligand>
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        <location>
            <position position="454"/>
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        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
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        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
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            <dbReference type="ARBA" id="ARBA00004874"/>
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            <dbReference type="ARBA" id="ARBA00008419"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
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            <dbReference type="ARBA" id="ARBA00022857"/>
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            <dbReference type="ARBA" id="ARBA00023064"/>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT98954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="491" mass="53674" checksum="04DBE100F7406BD3" modified="2013-05-29" version="1">MSQPVADIGLIGLAVMGQNLILNMNDKGFVVCAFNRTVSKVDHFLENEAKGTKIVGAHSVAELCAKLKRPRKIVLLVQAGKAVDSFIEQLLPHLEKGDIIIDGGNSHYPDSIRRTKELEAKGFLFVGSGVSGGEEGARYGPSLMPGGSPAAWPAIKEIFQATAAQVNGEPCCDWVGETGAGHYVKMVHNGIEYGDMQLIAEAYDILKRGLGIDEEEIATIFDKWNKGVLDSFLIEITTNILRYKDTDGVPMIRKILDAAGQKGTGKWTAIEALDAGSPVTLIGEAVFARCLSALKSERVRAAKSISGPQRETFKGDKQQFIDDLEQALYASKIISYTQGFMLMRETAKVQGWNLNYAGIARMWRGGCIIKSVFLGDITKAFEKTSDLESLLFDKFFNDAIHKAQPGWRRIVAQAVLWGIPTPAFSTALAFLDGYRSEIVPANMIQAQRDYFGAHTFRVLPGFESDRLKTGEDIHVNWTGRGGNVSASTYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU65</accession>
    <name>M5FU65_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040770203.1"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1180178_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25480" checksum="74599B9C7DA569B9" modified="2013-05-29" version="1">MPVGGTPGLPASAPQGAQYPVLVLPLFAAYSHGWNVQPQAAAPVVVPAEQPYTGQEQAHTPETSVKLRSNACQRCYKAHHRCGRKLPVCGKFAQSRSPCDDPKPSEDRKQLQRVERKHTSTSDSVASALKQPMNESDRGNSENVCGPDSESEIPVEMRDFERETLEHESPGEDINREDLQVPQINICDVSMSDEWAKTQQEETPGNIPAATGAALSALCEVIGISSEDATEPPCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU96</accession>
    <name>M5FU96_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625952.1">
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    </dbReference>
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    <dbReference type="STRING" id="1858805.M5FU96"/>
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    <dbReference type="OrthoDB" id="275637at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
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        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067326" description="Prohibitin" evidence="3">
        <location>
            <begin position="25"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="4">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="277" mass="30505" checksum="9B5F8ABF8635E517" modified="2013-05-29" version="1">MNVLSNLASRMLVPAIITLGAVQASLYDVPGGYRAVMFDRFSGVKNTATGEGTHFLVPWLQRAILYDVRIKPRNVSTTTGSKDLQMVSLTLRVLSRPDVDHLPKIYQNLGLDYDERVLPSIVNEVLKAVVATYDASELITLREVVSSRIREDLLKRASEFHILLEDVSITHMTFGKEFTLAVEQKQIAQQDAERARFIVEKAEQERQAAVIRAEGEAEAASVISKALSKAGEAFVTFRKIEASKAIVQALAQKRDVTWIPGGGNGTGVLLNVPTSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUD0</accession>
    <name>M5FUD0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_81387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626716.1">
        <property type="nucleotide sequence ID" value="XM_040776507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUD0"/>
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    <dbReference type="GeneID" id="63691569"/>
    <dbReference type="HOGENOM" id="CLU_007115_5_0_1"/>
    <dbReference type="OMA" id="AFTFQRN"/>
    <dbReference type="OrthoDB" id="343623at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032705">
        <property type="entry name" value="ORC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ORC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="6">
        <location>
            <begin position="46"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 4 C-terminal" evidence="7">
        <location>
            <begin position="231"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="448" mass="48867" checksum="3FCBADEEED47E5D2" modified="2013-05-29" version="1">MASPSASYSLPTPLPEDLHPYLQAQQRAVLSSLHQPSARTEGAEGAVAALSTLLRGTVERGEGNSCLVLGPRGCGKTRSVELALKTLPLTPLVVRLSGLTHPDDRSALRELHRQVLHSLGQATLPANSVEEDPEEEEDTAPFAALPPLQRPLVVLLSEFDVFCLRPRQALLYVLLDAVQGLRGGGMGIAVVGMTSRIDCVNLLEKRVKSRFSHRIIRVTPTKDAEEYIALTRELLTPELSNTPELEDGMDQWVGLWSKGVEVMLEDKEACTILRQTWELVHDIRVLQRILTELMTLLTPSKPWPTSALLSLSLTAQRAPNQHAHVPTLPAPALGLLIAVHQAGSAGHDVFTFQLLEHTYRAFARDHAGAFAGQGQGGAGGPAPRESLLSAFDDLVRTRIFTPAALAFAPAMREFSKYRCTLERVEIEDAVKKGGNTGVKKWLKSWSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUE2</accession>
    <name>M5FUE2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_81414</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626736.1">
        <property type="nucleotide sequence ID" value="XM_040776508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUE2"/>
    <dbReference type="STRING" id="1858805.M5FUE2"/>
    <dbReference type="GeneID" id="63691570"/>
    <dbReference type="HOGENOM" id="CLU_024839_0_1_1"/>
    <dbReference type="OMA" id="WIPVFAD"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="313" mass="33925" checksum="B0FCC0E4CA810962" modified="2013-05-29" version="1">MSDPSNNPIYRRLSAIPNIILVLSGKGGVGKSSVSVQLALSLYALLSRPRVALLDIDLTGPSIPRMLHLPQGTSVHQSTAGWVPAYADGEEQRLACMSTGLLLKRREESVVWRGPKKNAMIRQFLSEVRWGDDVDYLVIDTPPGTSDEHLSLLEHLSPLASRLSSVLVTTPQALSLVDCLKSLSFTRTVSLPLLGIIENLAGYVCPCCGEISNVFSTGGGEDLARKEGVRFLGRLPVDTKLVELLDGRLPEGMYAEEFKLLEAYKCTTNGKLFEGIVQKVLEGVERLGKGEEVPGFSEEDVIALREATSGVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVD7</accession>
    <name>M5FVD7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_17246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626472.1">
        <property type="nucleotide sequence ID" value="XM_040771270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVD7"/>
    <dbReference type="GeneID" id="63686332"/>
    <dbReference type="HOGENOM" id="CLU_650565_0_0_1"/>
    <dbReference type="OrthoDB" id="10524030at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="47799" checksum="6BFDFE0A71BECF33" modified="2013-05-29" version="1">MPIPNLPDDVLLLILQLLDLSEFHARSAVLYPLLPLALYLVYSLVYANLRLADTDHVALFLAHVRRRLAAPAAGEEATCLAGTRRLMLCLRDRLSPSAYADNCLHSLFSLLPRLKVFKALEAFSSRDLTALNQACGKTLESLELVLASDSLDRPTISSFSTLARLKSLSVTFYGRGRDVRIEFTDLGVLLPQVTYLKIMFIEWHCSALAFFSALTFPSLHFLSLSDTDVTSHPVLQAFFSRHRAALEILDMETRPEPICAWSFEALHTFSSLKKLTLRWVPDPGFCSQIPAALEELCLPLFYCRGRHTIRTTEMASYAKQWNFLDILRARAPRALKKLSGRNVYVGPYSTLLDWTKLLDHGDLVVVRRFMLLAAALEQKNIEFLDWKGERSPRNARWSTEISIANQGESNQPRRVVVLRYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVL2</accession>
    <name>M5FVL2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628758.1">
        <property type="nucleotide sequence ID" value="XM_040770173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVL2"/>
    <dbReference type="GeneID" id="63685235"/>
    <dbReference type="HOGENOM" id="CLU_618236_0_0_1"/>
    <dbReference type="OMA" id="HRAKNSH"/>
    <dbReference type="OrthoDB" id="3269291at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="443" mass="49882" checksum="C91118AC3A9601E0" modified="2013-05-29" version="1">MPMGETNPDFQKHMRRRDQRITEQPSDDQESNFDYPPRLQVIGSSSGLDRRYGSFSRAEEVVRAWRERNAKLTDESSASASSDNDGSPSSSGQRERRHKHKHKHRAKNSHDGATRSHRFDHSSRDHDELHQSHHSVRNATRELVRSTVTSDDPDRSVLVRQMLDGCRESCRQAGVSFEDILGEDMEGLEVPPLVYEIFTGWEDAGLLQFLLDNTPARHVEMFVRRGCMMRGDNTMFQVLRSALSASEKVDIVRYSLTMKEDAGQFQVEGSIECMPELLARVCTPVSDRKRPLPSPVEWIAAGRMWSIEPTAQNTLILRLLAGEPLKVVDADLTIVARDAASSSGRKNSMAVSMMKDKSMPVNLVPLSQSGVNTILFIPFSPMQERLTLPACLSADGALHFHLSLSFLNPSKSRDSSETEDWEKIAREQDWVLARWSGRGGEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVN8</accession>
    <name>M5FVN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Replication protein A OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624314.1">
        <property type="nucleotide sequence ID" value="XM_040771390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVN8"/>
    <dbReference type="STRING" id="1858805.M5FVN8"/>
    <dbReference type="GeneID" id="63686452"/>
    <dbReference type="HOGENOM" id="CLU_616804_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A OB" evidence="2">
        <location>
            <begin position="180"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="49403" checksum="44AD7DF598ABD81E" modified="2013-05-29" version="1">MTNISDTLTTNFCHSLLTNKTVCQDGVVQILSLKKVKINSTNLEPKQHKCKIRVCILRNTGGVKLKSKNGAFVCNLTFADSSGKISAVTWSNAAINPASLLTIRKLKIAEKMSIIELIDDGKVPPLTYNFIRLSELNLVRTTSCDVICVINMVDDEVILCNIKRPTNSAPVHILTDFVLASTLTPRVNDRMTIQEVQVVDASRYTCRVAVWGEEAIKFNAIIRDVIIIQAAQVCKHAGTSLLLEAGSKILFENGGQLMTFMELSDITFGASATACLSSMSGQDKLTTISDAIYNELGSDGNKTLFKTFAYLKDICTDQIAYHACQMLRCNGLVNPFMAEVPIQPQTDQAYVNEDSKETLFKMKQLWECCVCHKSFDDSCICYQLEVQITDGKESITMTMFDKVIEEMLQIPVHQVENMHVHQDPHLSRLAYGGLYKLGQRPSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW00</accession>
    <name>M5FW00_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624439.1">
        <property type="nucleotide sequence ID" value="XM_040775532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW00"/>
    <dbReference type="STRING" id="1858805.M5FW00"/>
    <dbReference type="GeneID" id="63690594"/>
    <dbReference type="HOGENOM" id="CLU_001324_9_5_1"/>
    <dbReference type="OMA" id="VISWEEC"/>
    <dbReference type="OrthoDB" id="3366231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="18439" checksum="DC95853F3923E1D6" modified="2013-05-29" version="1" fragment="single">GKTFLVDTLLAWLRSNGHIVLVVASTGIAATIYEHGQTVHSLFCIPDHIGILSEIQIPSGQADLIHAASLIVFDEMPGANKTTVEAIDMVCHHITSCDVPFGGLPFLGLGDFHQLAPVVKGTGETAALQASILSSPLWPMFKICHLHALVHNRDDPEFSAFVDYIGEDTSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW66</accession>
    <name>M5FW66_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629013.1">
        <property type="nucleotide sequence ID" value="XM_040772586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW66"/>
    <dbReference type="STRING" id="1858805.M5FW66"/>
    <dbReference type="GeneID" id="63687648"/>
    <dbReference type="HOGENOM" id="CLU_028897_2_1_1"/>
    <dbReference type="OMA" id="PDHANIR"/>
    <dbReference type="OrthoDB" id="2576082at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="50971" checksum="77728AB3041B7A63" modified="2013-05-29" version="1">MLLNLSFEDTSPIITYTNPSNPPAGSLLWGASTTTDGCRGLYSDSSFTGTNINKATMALTFNGTGIWIYGANRANHGNYSVSIDTQDFGPLSGYANDSGCTVLSDFKALLFGQAGLPMGAHDVTLTNLPINTSYNWVDVDYITIETEIGDAGGVQVQTSTVDDSSGQFSYSSGWSTSRATGQTSYLDGTLHEANTNQASVIINFEGQAISVFGGVDTPYGPFVAVLDSEEPLSLNAHSYDFFPQTLLYHANSLGEGVHKLTLFNGASSFDVDYANIWSDNSTIPLNPSPGTASGTPDGPGPTGSNKTSGALPTTSTPIGPIVGGVVGGVLFIALVGALLIFWQCRRRNRQIMETSALANSSLQPMRSIPAQHMSIPDHQADAHRKRAPPGIFGHQNTSSSAGLTTLASTISSPWSPVTNSRNTQSARGYPGPTIPSPAQPFILRDDDAWHLSGYPNEEEIGAGNGAETILLPPDYSQATYTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWC7</accession>
    <name>M5FWC7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_51821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629103.1">
        <property type="nucleotide sequence ID" value="XM_040775062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWC7"/>
    <dbReference type="STRING" id="1858805.M5FWC7"/>
    <dbReference type="GeneID" id="63690124"/>
    <dbReference type="HOGENOM" id="CLU_103041_1_0_1"/>
    <dbReference type="OMA" id="CCLHPRI"/>
    <dbReference type="OrthoDB" id="3267861at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="16675" checksum="C993911535BC93A7" modified="2013-05-29" version="1">MDGLTQVTSTVDEETGSILLCCLHPRINEYNDVMMYLLQCNMDIQYLASGEASTATLYYITDYMTKASLKVHAGVTAMLCAIQKNRDKFCEEEGVPCAVQSKSLVVKLVNQIGASQEMSHQQLMSFYVGGGDCYRLHNFSLLHWGYISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWF3</accession>
    <name>M5FWF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627586.1">
        <property type="nucleotide sequence ID" value="XM_040768725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWF3"/>
    <dbReference type="GeneID" id="63683787"/>
    <dbReference type="HOGENOM" id="CLU_2061409_0_0_1"/>
    <dbReference type="OrthoDB" id="3356461at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067278" evidence="1">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="13257" checksum="7333BDE76D2E63BF" modified="2013-05-29" version="1">MYFAAILATVLVALPVAVKSQVLTFYAYPQTSMFRHLFIMGGEQEEWQGAGPGRHVGNFEAPRYSFSICQTDHRCYLEIYEGLNQGGGSVQLWGDQPGDGTCSWTSPDYGYWSLSINCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWL9</accession>
    <name>M5FWL9_DACPD</name>
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        <recommendedName>
            <fullName evidence="6">Macrofage activating glyco protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_22015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629235.1">
        <property type="nucleotide sequence ID" value="XM_040772640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWL9"/>
    <dbReference type="STRING" id="1858805.M5FWL9"/>
    <dbReference type="GeneID" id="63687702"/>
    <dbReference type="HOGENOM" id="CLU_036093_1_0_1"/>
    <dbReference type="OMA" id="DVMGCMW"/>
    <dbReference type="OrthoDB" id="2564904at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067250" description="Macrofage activating glyco protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="35827" checksum="5FDEF65419DA3A05" modified="2013-05-29" version="1">MFSLVAVPLLLSAYTSAQYTATYLPSNAPPTSEQDQSGTNQCGSGHSQTSMCQNVYINSVQDFCLWAPPSTDGTNSTIGETERIEVAWCMKDGYGTRLIPDGTIKGAHFVQTPDYVQVTGFGDFTKMNIPAGDQGGELDPHGADGNGNPIGGLVFGSSFGQLQQYHEWTNYMAVDQFCIRACKDSPNAPLLCNHIYDVMGCNWNMPGNYDLGVFENCVGDTGPAMGIYVEGNTTSTFQQGQPVTPPAQPAPSSSQCSSFSTIQNGQTAAALPSASSGSSGTTTSTGSGSRMTSTGSSRNTSPTGSPSATTTAKSSAGHVVPTSMGGMFAVAGAMILGLVGGAVFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX80</accession>
    <name>M5FX80_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627257.1">
        <property type="nucleotide sequence ID" value="XM_040771235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX80"/>
    <dbReference type="GeneID" id="63686297"/>
    <dbReference type="HOGENOM" id="CLU_681559_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="404" mass="43778" checksum="9986D071F20E2A00" modified="2013-05-29" version="1">MGHNEPLHELHPQHGQQQLNSERQQQHEEELQLPLLHEATQLEDELQDPIQQHMQQPAEKLMKFLQQPEAQLHQEVNKLLVLQVQFLQHKQEQQKQSGSPTAEVDSAGSLQHTTPHHKDHSPHSPNTPESNFNVGQQTPDTSEHWDQPAARPGMLPQSHGTQSASASPSPASHSMATATATLLAEGVPHTAANALLFSSLPSSEALNAASAEAKVNAVINEAADKADWESYAADAASPSAVTASSHPASQEQTEAKTQESSASFPGTDVSAASASLSAPTWSAPPTGATSVNGTAAASSAAAPKKYLVKCLKLKVIQPFCPLPLLPIFVTEDNYASESPETRWMNLLHWFHSDKGPYAVPFVCKILDNTNLFTEEVKDMIVGPMGDAEQYDWPLQPEHLPTKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX97</accession>
    <name>M5FX97_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF952-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_80538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627966.1">
        <property type="nucleotide sequence ID" value="XM_040776450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX97"/>
    <dbReference type="STRING" id="1858805.M5FX97"/>
    <dbReference type="GeneID" id="63691512"/>
    <dbReference type="HOGENOM" id="CLU_129452_2_1_1"/>
    <dbReference type="OMA" id="NDEGWDK"/>
    <dbReference type="OrthoDB" id="3335358at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14847" checksum="09B91E1676990AD4" modified="2013-05-29" version="1">MSEPTPAPSYIYKILPTAPPTPLPDVFPLSELDRNDGFIHLSVHSQLLRTLSRFFADSEEVSLLKVDYPTVKPQIKWETIKSGEVFPHLYRDLTASDVASWKTLTRRTPGSSGSSNSGWEGALEQSVTEGWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXA8</accession>
    <name>M5FXA8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DIL-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_116901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627981.1">
        <property type="nucleotide sequence ID" value="XM_040770282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXA8"/>
    <dbReference type="STRING" id="1858805.M5FXA8"/>
    <dbReference type="GeneID" id="63685344"/>
    <dbReference type="HOGENOM" id="CLU_006124_0_0_1"/>
    <dbReference type="OMA" id="WSQVMYW"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051020">
        <property type="term" value="F:GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15473">
        <property type="entry name" value="Myo5p-like_CBD_DIL_ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037986">
        <property type="entry name" value="Myo5p-like_CBD_DIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="334"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="925"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="958"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1036" mass="116340" checksum="BCE5A519CC430173" modified="2013-05-29" version="1">MSVSSIISVSPSVSSLRFEPDLAPLQPKPVDLLPLLGDPDHLSVSQKRALASHALRHALLFADIALLIFLLNDPTAKPSLDLTIADEDGRGVLTIAMMGFGTEDAEREMDREECCRMLLVAGASIEKGDNAGWTPFHYAALMAPPTLITYMLQHCTSHGLRTEDLLNARTNRNGLTPLDVISAHTPLPGREGIILMLEDAMGVGAMKERMKREQREAERRRSEEKKEWLEERRKCLMTWGLGGWGEDDEEDELDGDEDMMMWDSDSDEEDVLSPPSSWESMLAFSLPSLQGFLMHLIDQQKPTLNPVSRRSLPAHVLWLCGRFAIAQADEDWFDEVLLGGLSRIEDIILNTNDVPILAFWAFNVTLLMYLLRTDKLVSGWADDFEHVGVALELLDYIYNGIVRSVEHRMAPLIDSTMLDFTPLGPDQGFDLPQYEGEWTFLKGVRDTLRLKKPASANNSPSSKPGTPKQAVPPPLPPKDPPRPPPKSSSITDIAAQAGGNIARASAEPKVFAELRKAVSHSRPRTPPGPGNFSPSSKDEPDIDSPRTLITLFSSLLRVLRLYGLNPAYIIQIFSQIFVWMHADMFNKVISRSKYLCRSRALQIRMNISTLEDWTSREGLPRSLVSKHFEPLSQLLQWLQCCSQIDQFSDLIATVQTLRRINPLQMRKAVRDYRYEVGESHMNEECNQYLQQMQRDWERRRLRIGVESMRKDMEARERERSDGGSSEAGFIPGLVETGQFSATDEQAEMRRAQEAIDALFDGETTMADWVPPQAPMAVGELQNATYILHVFWPTGVRHLMAEPGDSWNPSFTSPTSAFLTVPGRPTSAASMASIVSTRSSKQMEWKRRSARALRDTWTLLPQWIDALSPGVFWEDYRGNKYVKAAALDSEEEEENEVEQVEFDLLQERDSTLADLNKGLRLHTLREGLPEEDDEEEAVPEMLQGKTRSSGESSLLTPQPSDPPSIPPVIEPPPGEDAFHTPPASPLPEEPEEDKVELLRTTSVHSKVTIRRKLRRKRRDGSDITVKPDRKTSGTFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY64</accession>
    <name>M5FY64_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627637.1">
        <property type="nucleotide sequence ID" value="XM_040773094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY64"/>
    <dbReference type="GeneID" id="63688156"/>
    <dbReference type="HOGENOM" id="CLU_1175394_0_0_1"/>
    <dbReference type="OMA" id="FSEEWAV"/>
    <dbReference type="OrthoDB" id="10338496at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067418" evidence="1">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="236" mass="26378" checksum="0F79FAFECD62178C" modified="2013-05-29" version="1">MKATFVLSTLVSALLFAEAHSLKQASARDVAAHERFADLIARHPTPSTAPCVCPDGTPCKHSCGSDCGQNGQGQNQNRRSEKRDLWILETDFSGEVYPANVIAGLIKGDGVFTHTNGSTVTDWEYKINSEANRLTFWKNRRAGSGMLERIKRGFIQFSAPYLSKVIAIYFEDPDKVFMLSDNSGVKNKDVIRMAKHLLADKEQNEFMIWHHVIDRPTMEAVVSTLCPRLGPQYCEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ85</accession>
    <name>M5FZ85_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sphingomyelin phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_107557</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628721.1">
        <property type="nucleotide sequence ID" value="XM_040768501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ85"/>
    <dbReference type="STRING" id="1858805.M5FZ85"/>
    <dbReference type="GeneID" id="63683563"/>
    <dbReference type="HOGENOM" id="CLU_014743_2_1_1"/>
    <dbReference type="OMA" id="CYMKKIY"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF27">
        <property type="entry name" value="ACL091CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067348" evidence="3">
        <location>
            <begin position="18"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="254"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="685" mass="74546" checksum="A8F78BFE0407F7A3" modified="2013-05-29" version="1">MAAYLTVAMFCLASSLAQSPTLPPYLRTASPAFTGGIAFPSSLFAEYWPGFEPTQTTKEVQPIVTDPVTGSVFPLELTQPYPIQDGDFVDPYVIPPSLLTEQVTGPIIPTYNLSTPGSLALAAQTFQSIVDIIDTADIVDSCGKCQAALSIGKVLANTAPWEVPNVMVALCDKYNFATYGSCAETYGITSEGDVATQVLALADVAGQDGQAICAHWVGGACTVPPPNVLNMTGYFATAKPTNAVAPPSSGERVRVLHLSDFHLDPRYDIGSEVECSQYMCCRYNAYASSSPNTTLLPAPRFGAFQCDLPMDLAGVAIEAIPVLAGAGPTGREFDFAIFTGDLISHDNHNWPLQLGRTYIEYEESITFFLIQSALGSTPVYAALGNHDTWPQACAAPLTLEPEYLGNQFSWNYEHISALWAQKGWVDSTAYQYASVHYGGYAITTWRSLKIISFNSDFWYGDNWFNYINTTNPDISGQLRWMADNLQISEDAGQRVWIIGHIVERYSPHVIAEIFFGHTHEDQFSVFYANNGSDPSAASALATAWTAPSLTPLTNLNSGFRAYDIDPVTFNVLDSYTWISNISDAPALDAQAEHGAVFTFEYSAREAYGANISWPSTAPLNATWWHLVTEQWELNPSLIEKFYTYESKSSVKGGNCTSTACLQSMICYARSGSVPLAGLCPYGTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZK9</accession>
    <name>M5FZK9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_25371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623835.1">
        <property type="nucleotide sequence ID" value="XM_040774135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZK9"/>
    <dbReference type="STRING" id="1858805.M5FZK9"/>
    <dbReference type="GeneID" id="63689197"/>
    <dbReference type="HOGENOM" id="CLU_070631_2_0_1"/>
    <dbReference type="OMA" id="RAYIDPW"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.310:FF:000002">
        <property type="entry name" value="Sulfhydryl oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="72"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT96937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="211" mass="23928" checksum="E7C71034B2A27FA7" modified="2013-05-29" version="1">MLSRFTRVFLAISFLLILALISVFFNPPVRTYFDPWTGIELSEGGVEHRGSDDMLDLERVMTGDVIMGKLANETAKAELGRAAWRVLHLVTLRYPEKPTPDQRDTLKSFFYVFARLYPCGQCAQEFQQLLKQYPPQTSSRRSASLWLCHVHNQVNKRLHKPEFDCSKLDETYDCGCGTDPDNPDDESTPLIEGLSKDRVTNEALQKGGIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G057</accession>
    <name>M5G057_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630535.1">
        <property type="nucleotide sequence ID" value="XM_040772265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G057"/>
    <dbReference type="GeneID" id="63687327"/>
    <dbReference type="HOGENOM" id="CLU_059021_5_0_1"/>
    <dbReference type="OMA" id="WLECRLL"/>
    <dbReference type="OrthoDB" id="2145000at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052174">
        <property type="entry name" value="Flavoredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567:SF1">
        <property type="entry name" value="FLAVOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567">
        <property type="entry name" value="FLAVOREDOXIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16541" checksum="633C6ED8CC9E0CFC" modified="2013-05-29" version="1">MALQHDPPLIALSLGEWDHSFSALKQTGECVVSVPGVDLAQQVVDIGNCSGAQVDKWSKFGLTPLPAEVVSPPLVGEALANIECRVKDRTLVRKYSLWVLEPVRAWINDQREEKRTFHHLGDGRFVVDGERLDMRERMTMWKYLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C1</accession>
    <name>M5G0C1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629081.1">
        <property type="nucleotide sequence ID" value="XM_040770100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0C1"/>
    <dbReference type="GeneID" id="63685162"/>
    <dbReference type="HOGENOM" id="CLU_1077777_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="29006" checksum="17D81EDBDB85085E" modified="2013-05-29" version="1">MAHARPLPLALFRQPRRSCYLSPALPAFPRISSTLSRYSTATRTHPSASPANDPKPTQHPYLKPPAVLFPYHRLPRIQTPASLRSPTNPFARRPPGWRGMLGVKRNEKVKSLERHWRGREKSEDKVEGGTEESKKAHRLLLAKHLWASAPLLSLPPPPHAGKSLLTLSQPQLQEYIDHYTRALGPVPPFSLPTTRTAAWPSPAHVTRHALGLAKEWGVKVAHGVDWRCATRRDVGRVFLQVAARRRALKAGDRERKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C2</accession>
    <name>M5G0C2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_21184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="8"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772278.1"/>
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    <dbReference type="AlphaFoldDB" id="M5G0C2"/>
    <dbReference type="STRING" id="1858805.M5G0C2"/>
    <dbReference type="GeneID" id="63687340"/>
    <dbReference type="HOGENOM" id="CLU_030651_3_0_1"/>
    <dbReference type="OMA" id="WRAAYHN"/>
    <dbReference type="OrthoDB" id="8110916at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000023">
        <property type="entry name" value="ATP-dependent (S)-NAD(P)H-hydrate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="165"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="204"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="327" mass="35293" checksum="9F0AA87824DEDCDA" modified="2013-05-29" version="1">MAASSARILEQVRAIIPPLSAKLHKGQAGRVGVVGGSADYTGAPFFSSMSAMLLGADLAHVICEPTAGNVIKTYSPDLIVHRILDESQPVEKVEPIFKDIASRLHVLVIGPGMGRSDANQAFGRMALRVARQQGMYVVLDADGLWMVQMDPEVVKGYSKAVLTPNVMEFQRLCDKLGISQSEGDPTQLCAKVSLALGRVTVLQKGPEDIISNGVESWTVNEQGSLKRCGGQGDVLSGCVGTFLAWAKNFEEGEYTEKKPDTDSPHVSILAAYGAATITRTASRFAFAYKKRAMQSSDLLDHVGDSYEYHFGEGSSILEEIKKRTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1J0</accession>
    <name>M5G1J0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Voltage-gated potassium channel subunit beta-1 channel subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630985.1">
        <property type="nucleotide sequence ID" value="XM_040772059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1J0"/>
    <dbReference type="STRING" id="1858805.M5G1J0"/>
    <dbReference type="GeneID" id="63687121"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="YLPWSPL"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="32"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="357" mass="39961" checksum="02454B4C90617AC3" modified="2013-05-29" version="1">MANFKASYEYQPKGMVFRNLGPSGLRVPVFSLGGWLTYGGTVKGDPVKEVMKAAFEAGINMFDTAEGYEAGECEREMGRVVKECGWRRTDLIITTKIFFGVRRPGPNDKGLSRKHLIEGLNESLERLQMDYVDVVFAHRPDVTVPMEEIVRAFDYLINSGKAFYWGTSEWSARQIEEAMNISEKLGLIAPICDQVQYNCFHRQRFESEYDHLYKKYQYGTTIWSALASGILTGKYNDGIPADSRFTTNADFFKNTIEQLQKPEGQEKIEKVRKLTKLAETKYGCTVATLALAWAAAHPGASTVILGASKPQQVYDNLKALEIIPKLTPEALAEIDDILDNKPAAEPNYGRGVRGALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2A4</accession>
    <name>M5G2A4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_64040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631225.1">
        <property type="nucleotide sequence ID" value="XM_040775748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2A4"/>
    <dbReference type="STRING" id="1858805.M5G2A4"/>
    <dbReference type="GeneID" id="63690810"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OMA" id="QATYWAI"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="441" mass="48738" checksum="48BCD0D3A692DC27" modified="2013-05-29" version="1">MLMLVYFLGYLDRANLGNARIMGLPDDILDGDPTGVKFALINTAFYFAYITFQLPATIMGKKFSQNFWLGVAATGWGFCCAMQALTYNFANMFIARFLVGLFESMFSPNISLYFTYFFTRQEIGARLGTWFSCASLAGAFGGLIAFGVQQINSRVENWRLLFIIEGFPAVIVGLLCIKILPDRPDTATWLNEDERQLAVMRMSRGGLKEKPRTINARHIWLAVRDWKIYVYGVVYFGAASAASALAAFLPTIVQDFGYVGAQAQLFSVPPYAVGAVVLIITMPFSDRLESRGIPLTLAGLLGGTGFLLLIVSENVHVRYVSTFMICTSTFTSIGLAISWFPYNIGSESKRAAGIPLFQAIGQCGSVLGANLFPNAEAPRYFLGFGVSCGLLYLTGFCALCLTAYYRYENARRDRQYGQADRNAAVDTSELADNARDFRYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2I1</accession>
    <name>M5G2I1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-glutamyltranspeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20964</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631325.1">
        <property type="nucleotide sequence ID" value="XM_040772168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2I1"/>
    <dbReference type="STRING" id="1858805.M5G2I1"/>
    <dbReference type="GeneID" id="63687230"/>
    <dbReference type="HOGENOM" id="CLU_014813_4_1_1"/>
    <dbReference type="OMA" id="ICGMGPP"/>
    <dbReference type="OrthoDB" id="1081007at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.40:FF:000001">
        <property type="entry name" value="Gamma-glutamyltranspeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF9">
        <property type="entry name" value="RE13973P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="359"/>
            <end position="360"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="52363" checksum="9B878CA313A79826" modified="2013-05-29" version="1">MTIRPPEGGKAVSIDFREIAPAGSNATMFGKDPSTSLFGGLAIGVPGELRGLELAHNQYGRLLWKDVVEPVAKLAAGWRVQKELARRIPWLEMFGRKDQIAQEWKDIFAPRGEWLTEGEWIERKNFSRTLQTIAEQGADAFYTGEIAESIVAKIRATGGIMTMEDLASYEVIMYDSLVGTYRGNKVYTTNAPTSGPVLLHVLNMCEKFDFPGEGLTGLNVHRMVEALKFGFAARTEIGDLAFFLNRTARVAEISTKKFSTEKWEMIDEKRTHTADYYGPIFDIPADHGTTHMSIVDKDGMAVALTTTVNLIFGSQVMDPVTGVILNDELDDFSRPGIPNYFGFPPSPYNYPAAGKRPVSSTAPTIMERPDGSFLLAVGGSGGSRIFGGIAQVILGSDWGRDIGQSVESPRVHDQLAPAEVSVESTFPTDLVEALRVRGHNISLFDINDGRCEIQAVMAGEDGYLYAASDSRKNGIAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2J1</accession>
    <name>M5G2J1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_111497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624880.1">
        <property type="nucleotide sequence ID" value="XM_040769249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2J1"/>
    <dbReference type="STRING" id="1858805.M5G2J1"/>
    <dbReference type="GeneID" id="63684311"/>
    <dbReference type="HOGENOM" id="CLU_000288_6_13_1"/>
    <dbReference type="OMA" id="GHICADA"/>
    <dbReference type="OrthoDB" id="3038309at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="209"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="652" mass="73527" checksum="5EE31864A154E24F" modified="2013-05-29" version="1">MSPNADCAHGGPGEDTPEEDSWGLALMKDALTRLVGMNNELKKMSETKNEWFLFSQHASRIFEAVMTIASQEEESTRFTESVGDLALFINKLDQTCRRFESSKNVKKLLRSSEDAKELKSLRHELDDKIQLLQLHLNIEQRNFLLDAVKSLNLNETNTNKSTLRGEMSTNHSSFQPSAFLVLDSLPYASGASYNSSNTCMPGTRTALLSEITAWLETPSLESCPICWLTGVAGIGKTALANSVANIAAEKRWLVSSFFFAPNVGREEHTGKLVIQPCKNWDRTEPAVFVVDALNEGFDEGLLRVLTRQVKTLPRFFRIVITSRPLEKIRDAFGDASHIIRHSLNITDKQNGQDVQTYLRQRLTAVSIKRCLGQQWPTPSVFNELVAQSEGLFQWAFTITEYLRKCMNPIRQLDLIISLQGIPSVASRMDQLYATVLDGTGGKDDEDFVNAYQMFMGSILAAKEPLTLSAMRLLHGNRNVDPTELLERISSFVVGFDGEHEPIRILHLSLREYLMDRAAPPYRLSRSKSSQQLAFLCMPAINDHLSEVVVMSKQKRRSRSESLIPSNSPDLMWDGLYYAISFWDRHLLDARDPTPEFMSALEVLLDEHLQDLVSVTIALGAYKGLSDVRRWLQKLGPKGKQSLLRISDDYWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2S1</accession>
    <name>M5G2S1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_106591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629414.1">
        <property type="nucleotide sequence ID" value="XM_040768301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2S1"/>
    <dbReference type="STRING" id="1858805.M5G2S1"/>
    <dbReference type="GeneID" id="63683363"/>
    <dbReference type="HOGENOM" id="CLU_069661_1_1_1"/>
    <dbReference type="OMA" id="VCWEIWT"/>
    <dbReference type="OrthoDB" id="10259639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="186" mass="21260" checksum="332EDFF3E616FDE8" modified="2013-05-29" version="1">MTDSYKVVERPAGKEALRALLHLILFHRLFGCIKPRTTEIFDLTLPAVDEPEIDNIVNIKIDQFWKTLESSANSRAQMIVVFSEKRTKKSWFTSNEEEVPWEKWIIEAQLTSKADPPQRNNAQNSVTRSHLQRCMQRVLEHVDEKRDAVPPIQAQTLVPFPMSITVPHVPVADQRATSAATGKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Y8</accession>
    <name>M5G2Y8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cleavage/polyadenylation specificity factor A subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625025.1">
        <property type="nucleotide sequence ID" value="XM_040773772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Y8"/>
    <dbReference type="GeneID" id="63688834"/>
    <dbReference type="HOGENOM" id="CLU_104892_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25763" checksum="ADD0F3D1B3393F29" modified="2013-05-29" version="1" fragment="single">MKATEVPLAGGRWQWAGIVNGTLLLLTARLELCGYDYHGGQLMEVPILGTRALAKALRRMGSVRGGMLDNDPTNPAVLYLMLDFHLTATCTQVRNAHKNDSVCQSNTRLFRCTVVRSMTDAIIRDKARYSKSSGLVAATKNWICCTHHEGAYGLHLVNTRSKRIVSLTVPPMEFAQNAFFVQDMLLVMLTRCFAIYDLHDLGHLEVPIPAPPGPNLGYMELFKMNHMIWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D7</accession>
    <name>M5G3D7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_94451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629629.1">
        <property type="nucleotide sequence ID" value="XM_040777222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D7"/>
    <dbReference type="GeneID" id="63692284"/>
    <dbReference type="HOGENOM" id="CLU_1855207_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15953" checksum="33450587121CD8F0" modified="2013-05-29" version="1">MRSASPMPARTSNQLQGIETYHSRRNYETPLRKRAINWTMRPTTTIKVINCVLEPNRCLPGQSAVEPKLPCGLVNMLRTKNNGPHTNACETVRWRNEHAARLFTSKPTWLPQVRNIEARHTIILVWSISYWRSMDGQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3G9</accession>
    <name>M5G3G9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_118616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625205.1">
        <property type="nucleotide sequence ID" value="XM_040770621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3G9"/>
    <dbReference type="STRING" id="1858805.M5G3G9"/>
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    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="LGAWKMR"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
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        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
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        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
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    </dbReference>
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        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="30912" checksum="EBB3635BC70FB3DD" modified="2013-05-29" version="1">MEVNKPVVLITGCSEGGIGYALCEEFAPHAEVVYATARRLEAMTTFKHDNIRTLEMDVCIPKSIEAAVREVIEKCGRLDIVVSNAGVGAFGPILDVSVDWARAAFDTNYFGSHRLAQAVLPHMFQRKSGKFILVGSIGGLVPVPWNGTYAASKAALHTLADVLRHECTPFNVQVMTLLPGFVKSHIIDNMHGFNVSPTSVYQPWNEALQKRFSASQTNPSCMPTKQFAKIVVKELLRKELKWFFYSGGYSTWMWFMTLWPRKWALQYFWRRNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3M6</accession>
    <name>M5G3M6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24413</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625260.1">
        <property type="nucleotide sequence ID" value="XM_040773677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3M6"/>
    <dbReference type="GeneID" id="63688739"/>
    <dbReference type="HOGENOM" id="CLU_105974_2_2_1"/>
    <dbReference type="OrthoDB" id="2585651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF3">
        <property type="entry name" value="ANTHRONE OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT98362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17712" checksum="8A663CABE4BCB567" modified="2013-05-29" version="1">MSFELVPFLQVFAIAGAAFLSGALLFYSHSLESHSLLPRWEDFYDRGKLSAPFIGLFFSLLFVYISYSLGGPFTSSLAALYALAGAATVGIIPWTLGTMLPMNTRLQAYAAMKESEVQGEKAEKSAQQEVRRLFAAWTMNSIRAMWPAQGAALAEWALLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4G2</accession>
    <name>M5G4G2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_100756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627599.1">
        <property type="nucleotide sequence ID" value="XM_040767485.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G4G2"/>
    <dbReference type="GeneID" id="63682547"/>
    <dbReference type="HOGENOM" id="CLU_003233_0_1_1"/>
    <dbReference type="OMA" id="LLHEMNY"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF51">
        <property type="entry name" value="SNF2-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="975"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="875"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1163"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1199"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1291"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1297"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1339"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1370" mass="154091" checksum="7A851E3DDC3B3F88" modified="2013-05-29" version="1">MTPDSCQPPTESFAAGVIILSPQSLPADVPYDHWLSLPEPLLDFVFAALEEQDVLNSIFDLCLAGFARASIRGRRIETPIGIVSRLYIRLYLFPVSLEQSKNLLHHYHLLDMRERPRKLKPAVAISLALSWTSRDAMAWQCLGSGHYAKETLFFEQHSDNRSLSEVFQDLPSPVLPSPRPFKNESDRLLCEAMTWSAPPGMRSILFPYQRRTVWKLLQQELQPGTWADPRYVRIESLDDERPWYISADTCEVRSDTDVTYDRVKGGILCEEMGSGKTCMCIALCLATKGRMASPPNTPQASRVLTKDSMTWPGGEENLPYHNLDSGRDPSENEVIPNITFPSLRQIAQFVSYTSSPHSEHTIARMHTWAEARHVEHLKQVTCRFEEEREEVEQKKPGSTLPFYLETESEGKRRATREASKTLRPAIRIYLSSLTLILVPSMIFQQWNAEILKHCSDGALRVLSVPSRPVQDLSPAETLAFQYDVILMTHERFSAEGTPTSGRRSPLLDIRLQRLIIDEGHVANAENSRLKDFGLRLNVESRWIVTGTPTKNIKGLKMGSHRKKKKNEVPNGVDVVNSRLELLLSDSASNRPLSAWSRAHDGDDLKKLGNMFGFLMVPPFVGLDAAWGHVVSRPLLNPQGPEFGAMQRLLRCLEGVMVRHRAEDIEKDVPLPDLTQEMVVLDMTEHCAMTHNALLAQIAINAIDSERKDQDYLFHPKNRGSLGLVIENLSQSLFWHTDNETDYNERVRTAVKSLATAHTRGAPAEDIELIERSIGYLSRARDNEEWCSVMERMWVPFAVSDLPVEMRTWVRSTPLIRPDGICLIEPERISHIRGFAGLDQRKIVENNLNELAGLGSVYNIFDTELWNYVENMKEFRQGRQKNKSHTSSSSTSRDDDGMAVMAVQTASPSTVNGSPSTPKKKGRGKKEPPAPVLIDPRFESFRTSYPREIYNAAFPLGAPMTETTIGPSLSNKVNYILSDVLKCCTQEKVVIFSSSSLSLSHLAEAFELYRIRFLHFSNTLSVKDRENTIKTFETSDIYRVLLMELKHGARGLNLVSASRVYFCEPVWRADEESQAIKRCHRIGQTRPVTVKTLVTRGTAEEEAIRIRNAHHEQTRQMQDDRSIKHFIEYPQFVTGRTQEWPLLNTSLLRVQTDEEDGTILQHTSSPLQVSPERAKKRVRTEEDQAQARDNIELDIVPSRKPKKGRFHMTSPPSDGDIPLPATPNVRFVERSLPTPPESPYSTSPASRRAFLAEGDVDPVPPAALRSPLRLKIKVSRTRLPSTSAAIAAAAIPVPPPTGLSNSTGSSQSASPPVTPADRLAESSVPLKSAMKQPGMEGSEYVERSPKGTRFDLPGIVTLEEIDIEDDQLMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4K3</accession>
    <name>M5G4K3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_100785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627664.1">
        <property type="nucleotide sequence ID" value="XM_040767490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4K3"/>
    <dbReference type="STRING" id="1858805.M5G4K3"/>
    <dbReference type="GeneID" id="63682552"/>
    <dbReference type="HOGENOM" id="CLU_034385_1_0_1"/>
    <dbReference type="OMA" id="KNWRYPG"/>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="93"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="498" mass="55292" checksum="9D20055D0DA71D95" modified="2013-05-29" version="1">MATEQSTLPGVSKHHWHLTDVVYKVMNKSEDDSEAHKIYRSYPGHTAKGRAPATTNIAEETVPGIQHPGSTGVIYCTDRAMANGFSYDADGWANLGQGAPEVGDIPGALPKPTQIPIPHDSLEYAPTTGVKALRQAVADLYNHTYRQGMKSLYNYENVCIVPGGRAGLSRVASVIGDVYQIPEYTSYSSTLAAFKRLLPIPTALTADMEYKLDLEKTKKDVHEQGLQVIIASNPRNPTGQVIREDDLKQLVELAESKVTVVLDEFYSWYIYPEKEEELGQSVSAAAYVKDVNEDSVVIIDGLTKNWRLPGWRVCWVIGPKNMISALSQSGSFLDGGANHPLQLAAIPLLRPEVAQQDKIALQKHFKMKRDHVLARLNTMDLKVKVPPVATFYIWLDLSDLPGELNNGLTFFEELLKEKTIVVPGYFFDINPANRRDLFASPCHHFVRLSFGPPLDQLDLGLDAMERVLARARKGQGHIGAYKTWDVVEGVAQHIEKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4K8</accession>
    <name>M5G4K8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_95488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627674.1">
        <property type="nucleotide sequence ID" value="XM_040777299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4K8"/>
    <dbReference type="GeneID" id="63692361"/>
    <dbReference type="HOGENOM" id="CLU_1975747_0_0_1"/>
    <dbReference type="OrthoDB" id="10628887at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14178" checksum="8D09206E57889429" modified="2013-05-29" version="1" fragment="single">MSSSTPFFNDFPDCSRTGQHIRNVCGRCLFRCILRAKPGDEAKIPSLYCLLARAYLLVRSIPFHLDKAHAALQKAAPSGPHGVVALLNAAVWYSKGDINHAFELYFSLLKSNITTKELWWNVASVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5Q2</accession>
    <name>M5G5Q2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_53600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628024.1">
        <property type="nucleotide sequence ID" value="XM_040775185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5Q2"/>
    <dbReference type="STRING" id="1858805.M5G5Q2"/>
    <dbReference type="GeneID" id="63690247"/>
    <dbReference type="HOGENOM" id="CLU_135969_0_0_1"/>
    <dbReference type="OMA" id="YETEIWE"/>
    <dbReference type="OrthoDB" id="3358565at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF162">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067482" description="S-adenosyl-L-methionine-dependent methyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18709" checksum="06CA91343424502A" modified="2013-05-29" version="1" fragment="single">LGAGTGLVSLVLSALLSSRPNISVTITDLASAISLLEHNIQHNRPLLERTNIRLNVLDWERDLPDEIKSSGPFKLILMSDVTYNTASFSALLKTMRSLRQLSRDANVDTLAVLAYKERDIAERELWAMMEKEGFQFAKLEEITGHGGQPVELWFAQVSQCVTQVTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5V3</accession>
    <name>M5G5V3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_42624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626035.1">
        <property type="nucleotide sequence ID" value="XM_040774522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5V3"/>
    <dbReference type="STRING" id="1858805.M5G5V3"/>
    <dbReference type="GeneID" id="63689584"/>
    <dbReference type="HOGENOM" id="CLU_157433_1_0_1"/>
    <dbReference type="OMA" id="CEGVIGL"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="2">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="86" mass="9439" checksum="F0B47E39696C028C" modified="2013-05-29" version="1" fragment="single">MDATQLARWTRFAAKGGIGRGTALRDCVAEGPEDLMFMQGDEVVVLMSVAEGKYLGYCEGVVGHFQMTDVNLHGKLKKAIFTRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G649</accession>
    <name>M5G649_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_13650</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632625.1">
        <property type="nucleotide sequence ID" value="XM_040770991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G649"/>
    <dbReference type="STRING" id="1858805.M5G649"/>
    <dbReference type="GeneID" id="63686053"/>
    <dbReference type="HOGENOM" id="CLU_020019_9_0_1"/>
    <dbReference type="OMA" id="FTSHHYY"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="36102" checksum="A6DA6862894E91F8" modified="2013-05-29" version="1">MSTLTSPAADSLTIMSNESRPMSAGAGSGAPSTVVELNAYDVPVTMKDALQPRDIAPPITTPKTHIIFEVLAELLGTAVFVGFGTGANCQYAVGNGGQFMSFSTVPVGWGVGLALGNAFAARFSGGHLNPAVTLMLVLIGQVPAWKLPIYYITQVLGALAGAAITYGVYYHNIFVYDPGHTLERTAGLFGTLPAMDMPAFSCWLAEFFPSCVLIFTILYIVTLKPNPPFPVVPLALPKVLFLTILGVGCTFGSTTSFSMNPARDLGPRLLTWMAGYGKEVWNYKNQYWLWGGQLGAFSAAVFVSLGFHAFTWLERHLLDDRRGSTFLRIFNPLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G675</accession>
    <name>M5G675_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FH2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_62419</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. BNI1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632655.1">
        <property type="nucleotide sequence ID" value="XM_040775697.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G675"/>
    <dbReference type="GeneID" id="63690759"/>
    <dbReference type="HOGENOM" id="CLU_000718_1_0_1"/>
    <dbReference type="OMA" id="NHYWKAR"/>
    <dbReference type="OrthoDB" id="1104827at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051661">
        <property type="entry name" value="Actin_filament_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014767">
        <property type="entry name" value="DAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102:SF2">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51231">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="5">
        <location>
            <begin position="236"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="6">
        <location>
            <begin position="1144"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="domain" description="DAD" evidence="4">
        <location>
            <begin position="1565"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="823"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="912"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1583"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1628"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1676"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="727"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1525"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="846"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="975"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1011"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1056"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1099"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1676"/>
            <end position="1691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1717" mass="190409" checksum="AD3263D5A81CB260" modified="2013-05-29" version="1">MDTLFNRTRSKASSRASRPQLDLDSFGASDSDLRALPYDRTTLTRPPPFSGAQPARQNGQNGQNLLISAPNTNPGLTMNGTDLNINAYRDRQKERAAQRDQRRDNASNESVLYSLDEESSSLQSYSRASGTQTSLPIFSPASPAASTPQLPPISAQSDFNPSFPPSSASTARDGRFTPRLSTSTVNTLASDRSSRMPAPSTYSASESNTSFSRSRGAPSMMSLPQTPPVSSTAFYFPRPSPKTLQVMFEPLAEARDIPHVEMLNDDQKYQLIMSDARQKWEAAKHRSTRIEPSSTFTGNAGISGVGSMGGVDGKDAPEYYLKRMIDGKANVKDLTSLGVSLRTSTVDWVDTFVRAQGMPALCKVLTSIHVKNNPRPEDHLLELEILKCFKTLLNRHGTLETAVPRRGTIFTPLISSVCSPHLPSRKMATELLAFFIEYKDVDAWKVVVPALDNIEISPLQASKETQSGDAGLEGRFGRWFRTVENTLEGRGRMGTMVGATEEVRRGAGMDPALNDYAQMTFISIEGLIRKQPSADTRINLRSQMELAGLRRLLELFERMAAENGANSSTWSKLRNRLKNFNDLWETDERAVMEEYDRTVMKDMQQPEDVFKGILLKLGDTKSREYFELLMKNLLLLRREGEDRDKCFQIFAEFIASFVLEGRQPGGEMSFGDRFGASVTQLIARFGDQERLQKAEEGERFWRKKAGEEEAKGKALEAELEMGDAGLVGRLKADLKDMEQKLEKSRALTAALQQRMDIMAEEHRRLVASLERDIRELFRMLREARGGSLDTVLEEAKSARRQELVERVAAQMQRDDTIEILEGRRGKKKRASKAVVGSVDESESGEEPERVGAARRREQAKKGKRPSWAVHSRGLSLGGRTSQFMDADEERGMLEEQMLDEDARRRDPDATLRRAAAQRHTRVQGASEGEQLDSPFTPQTLLPPCRLRNGGAVSFDGDDSELGTIRESETDLSRISGDTQPTSLGSFSLDASATDSKDGKSLRLLRVKNTAVRGNSFSEQLANRLASMGKDPDDGSSPAEGPSSAVVGPNQGEPPQAQSPPPPPPPPPPPGGRGSPIPPPPPPGVPMTSALQAAIASRATSSRDTPGSTDPSSPTMPSPPPPPNPSRASGLNAHIIHLSGALTRKDIPISSTTRMKQLQWDKLPQQVVSKTLWGSAPQREAEREKEWVEKLLEDGVWKEMEEDFKAKQLVINLMAKQKRAELKSVLDTQTKKAVEIMIQRVKTLAPEEIALKILQYDQDLCTETFLGELKRVLPSPEQVGKLNVYRNSNPEELAELHPADRLMVQLIKIDRLAPRIEGMLYQSRFEERFTLIEDGATKLHDAGESLQRAAKFKELLSLILLIGNYMNGTGIKGGAYGFRVSSINKLVDTKSVNSTTLLHFLEKTVSRHFPDMEEFLDELAKPADAYRVNLQDIRKGLGELREGLTAIRQELTEFFSDVDALPPEDRWAKKMWRFVGEAGARLADLVDDVTLADTTLTEVLRFYGEDEKNMTSYEFYGIFKTFVTSYKKCKAENQATEADRAALERRKLAVQQARQARQQANEAIEDESADTTVLDSLLEKLRNGDTISRKSRRRQQSDQKQYDPPLSPTFEGASDGDAVELASNMLAQLKQDGFTPSTPISARPERASRRSRLRTKTNSTNGSIDAGYAGLLETAMSGLSDSRPNSRMQTLSEDGDYGLFSDEESTRAAVRGFMSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6C3</accession>
    <name>M5G6C3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_82437</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626215.1">
        <property type="nucleotide sequence ID" value="XM_040776568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6C3"/>
    <dbReference type="STRING" id="1858805.M5G6C3"/>
    <dbReference type="GeneID" id="63691630"/>
    <dbReference type="HOGENOM" id="CLU_025144_1_2_1"/>
    <dbReference type="OMA" id="TLLIHMF"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045016">
        <property type="term" value="P:mitochondrial magnesium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.330:FF:000002">
        <property type="entry name" value="Inner membrane magnesium transporter mrs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT99317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="457" mass="50253" checksum="745BA252FB94E607" modified="2013-05-29" version="1">MSYLRPLYTEATSSIQRRLAHLFPLSHPISHSIGRAYLAHHAAETFPSPTSSPSSSSARRTLPLHRSEYDSFSPTPLGDQEAEEAAKASILDVLINRQPTDLQLRCTVLDQEGNIKTISGKFRKADLCVEHRLNPRDLRKIDSRVPNLVPTILSRKDCILVNILHIRALIKCDTVLLFDTYGSVDTRLNSVFLYHLEHNLKLKSSVPYEFRALESVLASVVSALESEMVLTRQLTTGLLTDLEDDIDRDKLKRLLHYSRRLAGFRNRAKLVDVALEEVLEQDEDLAAMYLSDRRRGRPREAADHEELEVLLESFAKQVEEIENEASTMMGNVQSTQEIVELILDSNRNALLALDIKIAILTLGVGVSSVGAAIFGMNLRSALEESSVAFWAVSGSALVAAGVVSALGLGKLARLRRVGLGGGRKKAAAVGAGGRGGRGRWLGPPLRGWGGGKEVRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6K6</accession>
    <name>M5G6K6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Autophagy protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_87560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631223.1">
        <property type="nucleotide sequence ID" value="XM_040776816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6K6"/>
    <dbReference type="STRING" id="1858805.M5G6K6"/>
    <dbReference type="GeneID" id="63691878"/>
    <dbReference type="HOGENOM" id="CLU_024219_3_1_1"/>
    <dbReference type="OMA" id="WTKAMKC"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="4">
        <location>
            <begin position="45"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="3">
        <location>
            <begin position="177"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="97"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="40014" checksum="D4F4BD7A6A7F0454" modified="2013-05-29" version="1">MNVGSEPVVIAFSLWSVVATPRAQNLRHLPKLFDILSSRTGVDHPLCAECTHSLIDGLNKQLDEARRERDGYIAFEREAKRELERGRAGVGEEASHLDKLRQDESAAVLELSAAESELQKLEHELAALRSESDALDLEERAFWAEQASTQIASSTLRASLSSLRSAIRTSERELDALERTNVYDDAFCLGSDGVFGTINGLRLGRAGTVVVDWSEINAAWGQTLLLLHTLARKLEFTFDGWELHPLGSFSRISRAGKDDSYELYASTDIVVTRLLHNRRFDYAMVAFLDCLRQVVEFVKRKDSTLDFVYSINKDRIGDASVKLQFSQEETWTKSMRYILVVLKRLLRWVVNMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6L5</accession>
    <name>M5G6L5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_23947</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626305.1">
        <property type="nucleotide sequence ID" value="XM_040773476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6L5"/>
    <dbReference type="STRING" id="1858805.M5G6L5"/>
    <dbReference type="GeneID" id="63688538"/>
    <dbReference type="HOGENOM" id="CLU_129451_0_1_1"/>
    <dbReference type="OMA" id="KCYCVSC"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="128" mass="14236" checksum="4A48F9B3A7370135" modified="2013-05-29" version="1">MTKKRRNGGRNKHGRGHTSFVRCSNCSRCVPKDKAIKRFTVRNMVESAAVRDISDASVYQEYAVPKLYIKIAYCVSCAIHSHVVRVRSREGRRNRAPPPRIRFKDGKKVNPAVQAAEDAKAGAAAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6S9</accession>
    <name>M5G6S9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_44529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632855.1">
        <property type="nucleotide sequence ID" value="XM_040774587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6S9"/>
    <dbReference type="GeneID" id="63689649"/>
    <dbReference type="HOGENOM" id="CLU_091791_1_2_1"/>
    <dbReference type="OMA" id="MEEYVNE"/>
    <dbReference type="OrthoDB" id="3364670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19448" checksum="332431F0BA42B962" modified="2013-05-29" version="1">MEEYVNECCRHPHDQSSHRPRLPDLVSNGCQDSHLVANKNCKSASADTWVELGLMALVCWHDHPILLACIKGGSKKHCYALVLLQQLADMLPKAASISILYDIACQLSHGFEKWGYLPDLHKQLSFATLVFHAYVHQWACQAHFNPCKVLGFGMTNGKGCECLWSSMADLVPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7H3</accession>
    <name>M5G7H3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sc15 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626605.1">
        <property type="nucleotide sequence ID" value="XM_040770484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7H3"/>
    <dbReference type="GeneID" id="63685546"/>
    <dbReference type="HOGENOM" id="CLU_1427932_0_0_1"/>
    <dbReference type="OMA" id="SQITSIM"/>
    <dbReference type="OrthoDB" id="2575973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067556" description="Sc15 protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="19481" checksum="71BBD1B04DA9A9E5" modified="2013-05-29" version="1">MQLIRFSAFLAGMFALCNLGLAHPALTKGQADQSQITSIMDTLQSTVESAVGSLNGIDPSTATLAQVQPYVTDIEDAFSTAASALSSLNSSGRKRSSVTDVQGRQTAFEKEIAQLVAGLLTDVTNSLTGLLSVQGLGAILPNLDGPLNQTLLGLETLLAGVLNLVSGLLVDVAGLLTALGWGLTLATLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7I1</accession>
    <name>M5G7I1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_101319</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626620.1">
        <property type="nucleotide sequence ID" value="XM_040767543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7I1"/>
    <dbReference type="GeneID" id="63682605"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OMA" id="IMMAVLH"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="96"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="492" mass="52736" checksum="A8C13FB5F1F582C1" modified="2013-05-29" version="1">MEHHNSESVEPCTGESPSISLSRDVTAVDLPSLLPTFTEKEQPKCESDAPAETADIGIHSQSEKTLSDGNAVPVLVDEDSLETEDDDWTYPEGGRGWWVVTGCAIIAAVTLGWGLAWGVFQSYYKEHLFPDVPDSVLSVLGSIPGTIMNPIAFVVGKFADKYGYRLFLTAGCVVAVLAMLTASFSTTLWQFFLTQGLLQGCCTGLILPIAMAAPSQWFLRRRALATGIVIAGSSFGGGLASLVAQQLLTHIGLRNTLLTYTGVHAVLMSSSLLMIRDRPHPKSPRFTHARIQWVDASLFRRPLFWLVALSVTISTLGYLGPYFYIEQYTLTYLPSLDPALASLPAAMMNFSAAIGRSLIGLLADKIGVLNAFIGSLFIAGCMQLLVWNFAHSFGTIMTFSVLDGFFGAAFISLISVLGAKLFGVRNLATLSAILMIFSMPGQAAGGPLVGAILAASGGWQAPITYSGLCCVVGALVMIPARFVKEKRVLAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7V3</accession>
    <name>M5G7V3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_48830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631104.1">
        <property type="nucleotide sequence ID" value="XM_040774868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7V3"/>
    <dbReference type="STRING" id="1858805.M5G7V3"/>
    <dbReference type="GeneID" id="63689930"/>
    <dbReference type="HOGENOM" id="CLU_174457_0_0_1"/>
    <dbReference type="OrthoDB" id="3055037at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="1">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="82" mass="8808" checksum="3767D2C6E7DE56D6" modified="2013-05-29" version="1">MLSCAVTDGVSIGRPCCGVHNCTIPLSSNHAWYCPLHTAREASRAVEGCNNEAEPGRKTCSNPEHCLLEENYYAAGQSALQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8C1</accession>
    <name>M5G8C1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_109432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626905.1">
        <property type="nucleotide sequence ID" value="XM_040768877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8C1"/>
    <dbReference type="STRING" id="1858805.M5G8C1"/>
    <dbReference type="GeneID" id="63683939"/>
    <dbReference type="HOGENOM" id="CLU_005533_0_1_1"/>
    <dbReference type="OMA" id="WKLESRT"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="199"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="467" mass="51154" checksum="612060D5106053CC" modified="2013-05-29" version="1">MATSALAEIDVLQAALGTSISALKASIDSQGFSQFKSDDISPHPLDTGLPDPTTFYARRAIVGLCQQIIALVQDPAQRALIDHYNFLLPACIVAATETKPSFAEVMLEAPSGGITLDDVAKKTGIDRIKLRSFARMLATAGYVKEVSVDCFIPTRSTRGLAPGAGPVAEMNGIFSTYAPPATIVPKVLNLPSDSTTPAPFEVFFKTPFFPFLQENPAVLKRFHQGMTEIENHLDKGISADVHLDDLGSSITLVDVGAGHGGMSMQFLKHHPGWKAILQDRAEVIPQARQATQFWKDNMPDALETDRVSFLAHSFLEPTPLPPAPEGSPYVFLIKSVLHNWPDDMVKLMLENLVPAAPPGTKLLIINFTPSTPDSPHELHVDEFFDRINGKTMEEVQRMDLPVPLPLDVGFGAGEQYVSELDILMLLLFNSRARTAEDFRELLESTSWKLESRTRLRGASSLLRACRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8M5</accession>
    <name>M5G8M5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_75377</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631424.1">
        <property type="nucleotide sequence ID" value="XM_040776133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8M5"/>
    <dbReference type="STRING" id="1858805.M5G8M5"/>
    <dbReference type="GeneID" id="63691195"/>
    <dbReference type="HOGENOM" id="CLU_012243_2_0_1"/>
    <dbReference type="OMA" id="WNAANHN"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF137">
        <property type="entry name" value="PECTIN METHYL ESTERASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011119524" description="pectinesterase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="7">
        <location>
            <begin position="195"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="402" mass="43790" checksum="FBD3E1712BD8BABD" modified="2013-05-29" version="1">MVLGLLLLVLAAVATSSGSWNKYDACQRVKPPGHRQTDGCPEGTIYVSQNDGAAAFTNVQSAVESFPDDLSHSIILIAPGMYKGLVNVTRKGPVTLLGQYVLPTINLVTIWDDQFVTEPPPAQDDAQTAVLIVAPTFNASLIGMGTVGFPLQPEFGNADFKAYHIDFRNLAVRHIIQQRRVLTYCSSIHDISYANASFYGCNFASYQDTWYMGRNASTYVKGGTIYGETDYVFGFGAAYVLSDMWTRGCLRCTFANRGCGGALVAWKGTNQSDPTGTTPIAPGNHYGAYISNSQIIRSPDANTTLDLTGKCYLGRPWNDDATTLILRTYMDDTINATGFIPFSGRPQVILNTTYYAEYGSYGPGGNTSQRASADHVLDSAQAAMFTIPKVFGGWPDWIDYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8R4</accession>
    <name>M5G8R4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UPF0187-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_117242</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627055.1">
        <property type="nucleotide sequence ID" value="XM_040770345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8R4"/>
    <dbReference type="STRING" id="1858805.M5G8R4"/>
    <dbReference type="GeneID" id="63685407"/>
    <dbReference type="HOGENOM" id="CLU_029790_6_1_1"/>
    <dbReference type="OMA" id="GYDRYWT"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="531" mass="58771" checksum="A6556952D638FFB0" modified="2013-05-29" version="1">MARGKAKKPSHRLLPSFGTHLNAYFVPLVPTAELQTFAFIKPGTVIWKVWPAVLVQTALSAVIVYLAENAILDLSIDSVMLTVMGVVIGFVISYRASSGYDRYWMGRTAWSDVVRNSRTISRLIWYHVPPRLAPPKDADIRISMQEAELVLEEKKIALDLVQAYAISLKHHLRGEMGVYYEDLYELVWAVPHSVSESAELVASPSSMASLALPTIVEEVLPNSREGPALAPITVQPAAKIPPFIQFQVTKPTDRLLNGAYTQLDHSHNGIPHRMGTEPSQPLLPAKASARTRWSTELIPFETIFLHLFDLLLCREFESKAKKEIRRKARMSKHRPRVAGGGDNIPMEVLGCLSEWVATLDARSTVTGSPLGGLYGALQQFEASLTECEKILTTPLPFVYSVHLRHTVWLYLFFLPFQLARTFAWLTVLGVCCASFFYLGFLAAGDELEQPFGYDQNGESFSQDLDLDLFCKIIHDDIQHLMDSATPYSQLALNGGPVSQGRIAAGAVKELAGNESHTTSQVTSRPPSVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T1</accession>
    <name>M5G8T1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PCI-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_19740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 19S cap proteasome complex which acts as a regulatory subunit of the 26S proteasome, involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Component of the lid subcomplex of the 19S RC.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632038.1">
        <property type="nucleotide sequence ID" value="XM_040771641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T1"/>
    <dbReference type="STRING" id="1858805.M5G8T1"/>
    <dbReference type="GeneID" id="63686703"/>
    <dbReference type="HOGENOM" id="CLU_031814_1_1_1"/>
    <dbReference type="OMA" id="RLHCKVD"/>
    <dbReference type="OrthoDB" id="1452at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000005">
        <property type="entry name" value="26S proteasome regulatory subunit N7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="190"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00093435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00093502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="386" mass="43585" checksum="51458E612949AC3D" modified="2013-05-29" version="1">MAEDNVLPIPNLKLPQAQFVLFSPKLQTLHGKALEDLMAGIQADEMSPYYKVLLESTPSLKRDDALLKKMEEANTAAMAKLDEALANAEKTEGETEISDALRAKATYLTRIGDKEGALEAQKLALEKTPGLGSRIDIVLTMIRIGFFFQDNRVISEWMTKASELVEQGGDWDRRNRLKVYQGRHMLSVRRFKEASDLLLDALSTFTATEVFEYNEFVTLTVLSGTLTLQRVDLKKRIISSPEVNSVLPELPHLGDYFTSLYNCDYARFFRALADVEQTYLIPSRILHPHTQYYVREMRVLAYSQLLQSYRSVSIASLSAAFGVTPAFIDADLSRFITSGRLNCTIDKVSGIVETHRPDRKNALYEQVVKQGDVVLNEIQKLSKVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G938</accession>
    <name>M5G938_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627200.1">
        <property type="nucleotide sequence ID" value="XM_040767498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G938"/>
    <dbReference type="GeneID" id="63682560"/>
    <dbReference type="HOGENOM" id="CLU_489168_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="557" mass="61151" checksum="82AF9021F20CBCC3" modified="2013-05-29" version="1">MASPSTTRSSVATSSRASATSSRSVFTETRLSAVTKSTVSSAQISSTPMRSSTSGITTTKHTHMTVDGVVRDELGHALYRNCSIENILQSISDLDDAQLLERQELARDLAQKFSEDEELKCLEENYLRQSLEPQAYVPFCELVNAIIDHLGIEGDNRFLAIGQKNMILAHGMGDQKSDVVFVTKSVYDVSMKKLGPVTSGSVVSSSASLEHHNKSSNEVETILDAARALGFVEMKWEKRKRSRTLATASKRTPRPAGACTSQRNSDQPSKSSLSDRSKLQATATKRARSPSADGTLPSKRKKSPNGYTTTPAQPISPFALDGPGVIPPTGSEVQLGGYAMKGQSDGCFRQWTVARSLAVHWFQSLGLHSHHIVGQREHFMLLLLLFTSASPSQLGMNTAIKDTIDADVGRGTTAYRTRFASEDVVVMVCFPPKTRKSEVEFIARFRQHADIMDMVPKVFAHSTIEMPDFLELVLRSKSKPKVEPDVRQMRVFVMKRYQTLSEVTSADDLLSIIRDIGRYPDSKDIMGGGTDWLTHAKGRLNGLEALFGIDDNTTVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G971</accession>
    <name>M5G971_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627235.1">
        <property type="nucleotide sequence ID" value="XM_040773175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G971"/>
    <dbReference type="GeneID" id="63688237"/>
    <dbReference type="HOGENOM" id="CLU_2757722_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="70" mass="8125" checksum="B74EEE009F229DF5" modified="2013-05-29" version="1">MDIQWATVRVKPGRLPSRLSLLDPQNMSFVDLLTMYEHVHEQQIRHGDEFSFFESSDHLQANPETLVNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA48</accession>
    <name>M5GA48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629711.1">
        <property type="nucleotide sequence ID" value="XM_040771104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA48"/>
    <dbReference type="STRING" id="1858805.M5GA48"/>
    <dbReference type="GeneID" id="63686166"/>
    <dbReference type="HOGENOM" id="CLU_1415119_0_0_1"/>
    <dbReference type="OMA" id="MQMFENI"/>
    <dbReference type="OrthoDB" id="431454at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21366" checksum="67C1CFE77C7AD21B" modified="2013-05-29" version="1">MAQCLYTMSGILCIQEHYEDLAQLLQEVKAEFKVLVNHLSIAKCMQTLSDVQHMQTHYSDAVPLLKEARMLFEAIPHATGVAQSIQTLSDVLAQQGYYDDAAPLLEEARDMFEAISNTLGIMQCTQILRDILQRQAQYDTTTQMLQEAKVMFKAISEPLGAAQCMESLQIIQAQAVLEAIPKPGSTAMQQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAT4</accession>
    <name>M5GAT4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_115347</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629981.1">
        <property type="nucleotide sequence ID" value="XM_040769986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAT4"/>
    <dbReference type="GeneID" id="63685048"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OMA" id="VAFANIQ"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="48"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="557"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="577" mass="63485" checksum="198022F0981C1817" modified="2013-05-29" version="1">MSPPRMGVEQQTVSRTFSTLERHAKSISDDEVDQHKPRLRGWTLHIVLAFCAGAGFTLFGYDQGVMSALITANQFDAIFPQTVSPINDPTGQAATLQSLMLAIYEIGCLIGALSNLWIGDKLGRRKTIVLGGCIMIIGATLQATAFSYPHMLVGRIVTGMGNGLNTSTVPSYHAECASPERRGPLIMVEGSLIIFGLMISYVSTIGKWVDFACYWATGSQAQWRVPIALQIVIAMMMMCGIPFLPESPRWLVKHGRNAEALAVISALEDTDRHNPRVVQTYAGICEAVEAELEGSSKEKLSRLFQGGPTQNFRRTMLGIVNQCFQQITGCNLVMYGHRRCVELRLKEGFHRYYATLLFQRLGLSDVNSRIVAACSGTEYWLASLIPIFIIERVGRRRLMLLGAIGMGTAMVLLAILGSINTPAAQIASTVLLFVYNSFFAIGWLGMTWLYPAEIVGISIRAPANALSTASNWTFNFMVVMVTGPSFANIQWRTYIVFAALNALIVPCVYFFFPETAGRSLEDMDIIFAVAYAEGVSPVQVSFRKDLPVAGSPEADEVLGLKKRGESPDVREDREKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB92</accession>
    <name>M5GB92_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_89083</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628140.1">
        <property type="nucleotide sequence ID" value="XM_040776893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB92"/>
    <dbReference type="STRING" id="1858805.M5GB92"/>
    <dbReference type="GeneID" id="63691955"/>
    <dbReference type="HOGENOM" id="CLU_033999_0_0_1"/>
    <dbReference type="OMA" id="EDHNAYI"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="352"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="9">
        <location>
            <begin position="378"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="439"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="470" mass="52649" checksum="C1BB2AD14D331618" modified="2013-05-29" version="1">MPGIVLERSATQALPSRAGDPTPRQRNLDPSLHPFARAREYTRALTAAKLERIYAKPFVCSMEGHGDGVYVLARDPGRLGVVGSGSGYGEIMLHHLPSRTQVRKIKAHTSTVSGLTFTRTRQLLSCSPDRTIKLWSADAGTDTRADDEDEYYNSLAIAPQPRAGGSTGEAPLRVFQGKMAFNAVDHHRTESQFVSASNTVQLWDETKMDPILSMNYGTGVETVLTVRFNQSETSVLASTGTDRTMCLYDVRTGKAERRLVLQLRANALSWHPTQPTVMLLASEDHNLYTFDIRKLESPTQIYKGHVAAVMCCDWAPTGTEFVSGGWDRTVRLWREGEGGSRDVYHGKRMQRVFAAQYTADARFILSGSDDGNVRLWKAQASDKLGVLDGRERAAREYRAKLREKWAHAPEVRKVERQRYLPKPVYSAGKLKRTMLDARKVREENARLSTRKGREGKPKAERKKVVLAEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBJ3</accession>
    <name>M5GBJ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632664.1">
        <property type="nucleotide sequence ID" value="XM_040771820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBJ3"/>
    <dbReference type="GeneID" id="63686882"/>
    <dbReference type="HOGENOM" id="CLU_609756_0_0_1"/>
    <dbReference type="OrthoDB" id="3362331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="449" mass="51546" checksum="51C648F01E51DFA8" modified="2013-05-29" version="1">MHSSPTIKAQGGTGARQSHSFPLPHFAPRVPTQHSLKPRYSPWPTTPEEESMDAQWAQWYAPYLQQLGTYGWVWDGKRWNWGAQRVEWFPMKTEETWLDRGIDPRLIYRSPSPETEETVSSPCTQRSSLLDSPDGSSQSSLPPSLFDFGSEDEEELETRMNECFTTPPTEYEQRGGKRKYLEELGSEGSEDGDDECDDQDLNYTKPKPPKRPRLSKLSGKRRPQRRRPPPSRDVKPRAIRRLVAHPPPVRPQKAIHEQTEVVFSCPYHLSSTPHLTCGACFSSETDVRRHAATHLAKEYYQQLNSSLPAENYMFAGLAPRFIYCSHTWCSRPFLRKDALPRHMAGSCLCIADRSKKGKKERLEQARALVLRGKEHWVHTPARMPHSVEAVTAKVEGQQKRVITRIVRVLSTYGDSFDIKRVKDGEEMEVWWARGKGKGNYKVFERALDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBR6</accession>
    <name>M5GBR6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Structure-specific endonuclease subunit SLX4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_113138</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633323.1">
        <property type="nucleotide sequence ID" value="XM_040769571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBR6"/>
    <dbReference type="STRING" id="1858805.M5GBR6"/>
    <dbReference type="GeneID" id="63684633"/>
    <dbReference type="HOGENOM" id="CLU_408273_0_0_1"/>
    <dbReference type="OMA" id="HITRHIS"/>
    <dbReference type="OrthoDB" id="5576441at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018574">
        <property type="entry name" value="Structure-sp_endonuc_su_Slx4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09494">
        <property type="entry name" value="Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="432"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="492"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="626" mass="69489" checksum="5E270B6E67A87CD1" modified="2013-05-29" version="1">MLHITRHISTILKDKENFAIMPPLSSHNDSPRDEVVEDSEPEREEQRRKLKAAKKATQSTVRPPLSVIPVDTEPVPVDVEGSDNLSYKHLEGSAPSIVLYTVEELSASTGPEAASTSFPSLSHDDLPKYGHPIPVTRVEENGPDALEPVRTLNLTHFANNATVVQHNRRSTSPAPVISSLNQARALSTSTAPSRWLNCPLPEKRMKIITKCPCCELAWTARKSSQMKWEHIARCAKKNDYTVETLLTRLDQQLASTDTINVEGKSKKRKAKTPLEQKEVPKPDTLLERVTHEAVPPKRGRKQAVPETVQNVSQAHQLITEKARDVLLAGESVVPAPHVESATSPVAAQLPLATQAFVPSKFGGARRTVSLLNDNPLKERPPDAGATLTSDRFSYLPRDVSPGPDISSNAVVPSEAQTSLANLTASTLDLTSSPATAFRKPRSSSPKKRLSLRQIVRQEDTLHNSDTDSISSENGWVDEGAWGADTVLVWDGDRSDGSTSSSVVLSKAKGKKNKGEGPLTSPIQAPEQPKKRGRQRKDVVVQEKESKPTDEETVAMIEKELRTMIEEDEELYLRILRYEPMKFDDLLKRALDRELPERKLKERLRNFLDKQCINFYTAEPTGTRKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBS2</accession>
    <name>M5GBS2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632779.1">
        <property type="nucleotide sequence ID" value="XM_040767920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBS2"/>
    <dbReference type="GeneID" id="63682982"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22172" checksum="124B2DA930D7592E" modified="2013-05-29" version="1">MTQLTARSDMIVFAGARDPAVYVVKLRAAGEGDANVETIKKVVGRLDVMIAIAGMKNGYQPGTEGLFGRHGGALRGSGNALDPLVLFQAADSLLKKSYNPKFVLVSTSARSVELGTKLSMPIMCYGSTKAAVNLIAAKLWHENPQIAVLLLHPGFVRTLLGIFIPVRSQLKSFELISPDQSVAALLKLIGSGIIKERCVWAVREQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBY9</accession>
    <name>M5GBY9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628440.1">
        <property type="nucleotide sequence ID" value="XM_040772901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBY9"/>
    <dbReference type="STRING" id="1858805.M5GBY9"/>
    <dbReference type="GeneID" id="63687963"/>
    <dbReference type="HOGENOM" id="CLU_148189_0_0_1"/>
    <dbReference type="OMA" id="QWIAPNV"/>
    <dbReference type="OrthoDB" id="3365917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="173" mass="18266" checksum="B59020590566FA13" modified="2013-05-29" version="1">MTLIQSSNTSVSSNASLPSNTTSNSTIASNTTSAPLNTYAIMGDSDSVRAVLDALVLNCSVINSTITPYSSSASNSAQPEQAVQYYRASSFALFLEGYNNTAASAANAPPSNTTASNVTSDTPLPNNINLDFLDCLNQTIGNAVPMTNNAAGLAPVWRLIIFFLLVWFLARRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCH0</accession>
    <name>M5GCH0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_112948</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633094.1">
        <property type="nucleotide sequence ID" value="XM_040769535.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GCH0"/>
    <dbReference type="GeneID" id="63684597"/>
    <dbReference type="HOGENOM" id="CLU_000709_1_0_1"/>
    <dbReference type="OMA" id="AKLYYAF"/>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000340">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001008">
        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1182"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="1563"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1828"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1053"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1344"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1606"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1696"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="429"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="932"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1061"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1719"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1748"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1770"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU06200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1963" mass="212798" checksum="6431A3EF991BBAB1" modified="2013-05-29" version="1">MARPNSLQMFASSPPTLPFTSVPSSTATSPSPNAPTPASTPAPPTGTSPSASQISVASHPSYIQRHFRRRLQASKQACDTELKKVIHAVTAYVEHSLRAQQEAEWEEEEEARLHERDDLLAVESTSDDAGDESDAGGGVRRKKKVSNTHRHRRSFMLSSGTKLPPMGASTALAIPGTSATHPIQAAPQAGGPSTSPVRMSASSSPTSTWNRTSNIVVRRASRSRRYTLSPPLPATVPGNVPPPLALQPAPLPGATVPLPPSLAPSRASSRSRSRSPLPAATARARSPIGSPTSELPQSDSSPAAKLDFISTLRDLVSLSTTLVEMPLSTLTSPSSPHALSEIVQNVQALGKAWDLRPDWHGRGWYVQVLLAVASLSRVVEWWQAEREFWHFGEEGEDEDEGEVEGMTFVLKPADDEAGRGGSSSGGEESTDRERDHEKHEVEERSFFDRERTVVPDDKIPSPLKITPPKERDDPLSGTHLVPSAPSPIKDLPSREPPLHVEISRTKANENLRTSAEKAMNEQVVMEIGLDGERILWVSPSWERVVGGPADNVAGTSIVSLLAPADQNVFVQATHHLEVEDPLTIEAKFLMLINPPTRPAPEGLPSPQDNGRPYFIEMDARGMLVKDRIGGEASHTLWLFRPLPTASPISPSASQLQQDQYEPMVTGLGVTGEQEVSVAFHERGKMEPVTPFPFQRPINTSTILCRICELQVPDWFFEKHNETCNEVHKLEADIVECDDSLQELVNTIAQMVVSIDRLGQASPVPGQTGAVPPAQPSVPMRDPLPEYRGVSLFTPGTAPSSPLQSGGLRTSASARLQRVTVRKMQRKLLEDLQEILQAAREIDMPAVNEDAPNVPLERRPFLTPQSEERVALVNKWQKPQTDDPALAQLVQDAETLMRTKVEYVRRMINTLIYSEKVRHEWEEKVEQTLQELESQEGDDADSEPSDSGHEEGETPAAPSTEQPTVVAPSPIPFEAAPASSLAALPAQTSINFVPVPSPASLSPSPPASLSSLSSPYLPVSVLQSASPHPISPLTTSPLVPSPLAFTTPILAHRESDEHHSSEVASSASADAQSSLQMTLGSPAAVPPTVSSIQARRTAVNALAEPTVMVTPPFSPALPATAPSSITLPPANMTASQSSISSKHNRRLSTALPFSPAMSAGPLSPRIPSIAPTSKTTPSSIRDFEIIKPISKGAFGSVYLAKKKTTGDYYAIKVLKKADMIAKNQVTNVKAERTILMQQADSPFVVKLFFTFQNKDYLYLVMEYLNGGDCAALIKTIGALPEDWAKTYVAEVILGLENIHARGIVHRDLKPDNLLIDARGHLKLTDFGLSRIGLFGRQARDGRAFAYRRGSGNHRGRVPRSGFPSRQGSIDSGVASPSPEVAVETPNSFAPSSYFTRGLSPSHLSTSVDDVSESSGSESISGMFQRGLALASESPQQSFASELTSDLRSYNTGGTTPPGEQKFVGTPDYLAPETILATSEDDRSVDWWALGVVTYEFLYGFPPFHADSPSQVFDNIISRRIDWFDEHVDFSKDARDFMERLMCTDPTRRLGFKGAQEVKAHPWLSDIDWEHLTSKTAQFVPQITDPESTDYFDPRGAHLLLFQEEEPLQVAESSNSSPRAERLSLRPGSTHPMDTPDPGLSPAIDDFGAFSFKNLPVLKQANDDVIKKLKAESPLQGPGSLPLMSLHGRRSSISQRFRNKQTLGMGITVDGKGITSPPSPSTSTSSIASTPSRANFPPLTLGGSPGHVRRPSEHGVLDRFKTQHEDGIRRNSMPSRLRTASVSSGGDHTSGTEGTSSWQPAPMEVGTPATSVGSHEMRRGSDPKIDRTIVCLLAEDNVISQKVQEILLTRLGCRCVLVSDGYEAILAACGEIQFDCILMDYQMPILDGELATRFIKGTNNRNKMTPVIAVSAYSALDPSINADLFAGSLSKPVQRDALLAVMKKLGFKVTTETLGSKQTRRVVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCT6</accession>
    <name>M5GCT6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_107689</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628860.1">
        <property type="nucleotide sequence ID" value="XM_040768515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCT6"/>
    <dbReference type="STRING" id="1858805.M5GCT6"/>
    <dbReference type="GeneID" id="63683577"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OMA" id="KATWMEC"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="9"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="498"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="538" mass="59278" checksum="D450C1101D286EF0" modified="2013-05-29" version="1">MGYLKSILFCVFVAFGGFLFGYDIGVISGCLVMPDFINRFGEPTGPNGEMVLSATRQSLITSLLSVGTTIGALAQAFTADSLGRRASIAFWAGIFTIGVAIQISTTYSLGQIVFGRFFAGLGVGAMSAIVPLYNGEAAPKKIRGALLALYQFQIMSGLFISYCIDLGTSNIANSASWRIPVGIQMLWGLILILALFILPESPRHLLGLHREDEARRSIAILNNVPIDDILVHETIDELREAIREENEGGKATWIECFSHRNKLYWRTINGMMLQFVQQLNGQNFYYYYGDTFFKSANLNMSAYVIQVILGGVSVVATIPGMYVVEKWGRRTSLLVGALWQAACAIIAGLVGHYTLAPVGTPPDQLTARNIAGGDVLIAFAIIHVFAFNMFWGPVPWVYLGESFPLRVRPKAIALGSATNWVWNFLLGYFSPTIADEIGPLITMVFFGMLIYGTVYVYFFVPETKGLSLEEVDEMYRSGVKPWNSAKFKPHDRHLHAKEHGDLNKPVEFVPETEEGSLGQGSGEKKDSAREETTYVENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCY1</accession>
    <name>M5GCY1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633389.1">
        <property type="nucleotide sequence ID" value="XM_040771595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCY1"/>
    <dbReference type="GeneID" id="63686657"/>
    <dbReference type="HOGENOM" id="CLU_2145765_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12075" checksum="274635BB739CBF4E" modified="2013-05-29" version="1">MFMLEDGDGRWDECGIEGASEGICRAGTDGRDGAYVRCAAIDEQSRRHAAPTSPPFKAGRRKTTQISCAPPPERAQAYELNRYTPTLRASFACTTAHSRHTVGSAQLLECGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD88</accession>
    <name>M5GD88_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633554.1">
        <property type="nucleotide sequence ID" value="XM_040767789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD88"/>
    <dbReference type="STRING" id="1858805.M5GD88"/>
    <dbReference type="GeneID" id="63682851"/>
    <dbReference type="HOGENOM" id="CLU_2432825_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11707" checksum="52924FFD43B4A7D8" modified="2013-05-29" version="1" fragment="single">MPIIEEISKGPEVGTIDAFDEAIELLSKDLPIPTEFMADDVPTDPEKVAKLKEWKNATEMHLYKLQEYLRTKPELELEQRTRVVISAGLLRGEDSFSTSTMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDD1</accession>
    <name>M5GDD1_DACPD</name>
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        <recommendedName>
            <fullName evidence="12">Guanine nucleotide-binding protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_20970</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631336.1">
        <property type="nucleotide sequence ID" value="XM_040772173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDD1"/>
    <dbReference type="STRING" id="1858805.M5GDD1"/>
    <dbReference type="GeneID" id="63687235"/>
    <dbReference type="HOGENOM" id="CLU_014184_6_0_1"/>
    <dbReference type="OMA" id="GNCISQM"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU04442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="40469" checksum="C4BF807A05C6CE8C" modified="2013-05-29" version="1">MGCMQSSPVDSEAKARNDEIENQLKKDRMNAKNEIKMLLLGAGESGKSTILKQMKLIHNGGYSDSERESYREIIYSNTIQSMRTILEAMQALDIPLNPANDARRDVVLSLPSQLETEMMPRDVADAIRGLWADDGVKEAVRRSREFQLNDSAVYYFNCLDRMASPSYLPTDQDILRSRVKTTGITETTFRVGELTYRLFDVGGQRSERKKWIHCFENVTALVFLVSLSEYDQMLYEDESVNRMQEALTLFDSICNSRWFVKTSIILFLNKIDLFADKLPVSPLSDYFPDFTGGSDYDLACEYLLNRFLSLNQQAATKQIYAHYTCATDTQQIKFVLSAIQDILLQLHLRECGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDG1</accession>
    <name>M5GDG1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_79168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629257.1">
        <property type="nucleotide sequence ID" value="XM_040776380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDG1"/>
    <dbReference type="STRING" id="1858805.M5GDG1"/>
    <dbReference type="GeneID" id="63691442"/>
    <dbReference type="HOGENOM" id="CLU_1704181_0_0_1"/>
    <dbReference type="OrthoDB" id="5598852at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="17491" checksum="E53EC3C72F98AEE4" modified="2013-05-29" version="1">MPVFEDVAAFHAWIKSLTRQYWPLVQPKLEKTFAKYDNTPTVFTHGDIADHNILIDGGRISGLIDWETSGWMPYYWENVCCEEVGPPKAFKKVVEIALADFGAGEGEGISQAAETTNNRPPREFMTKEQRRYFYGDNCLDESDNSVPELPAIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDL3</accession>
    <name>M5GDL3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_22129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629402.1">
        <property type="nucleotide sequence ID" value="XM_040772690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDL3"/>
    <dbReference type="STRING" id="1858805.M5GDL3"/>
    <dbReference type="GeneID" id="63687752"/>
    <dbReference type="HOGENOM" id="CLU_016972_2_1_1"/>
    <dbReference type="OMA" id="GIYDSTC"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067690" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="26"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="405" mass="42154" checksum="41C1C339E6FC3926" modified="2013-05-29" version="1">MKHNLACVAFAATLPLVRAAGFNIVQNWQGTTFFDNNWSYYGSWDNLTLGDVNFVTQAVATAEPELTYVNAAGNAIVRVDNISTVAQPNKRNTVRISSVETYGLGSLWVMDALHLPYGCSVWPAFWSQATKWPEGAEIDTMEQINMASSNQMALHTQDGCMASSSANMTGTVTDPDCGTDLPTKTQGCTVTEPNTASYGAAFAAGGGGVYATLLVESGTYIWFFPRGSIPSDLDISNPNTFPNPDNWPTPSAAYLSSTCPTSMFLEPQHIIIDITLCGAWAGVPQTLDATCPGVPANAPSSYCYTTYVAGDGSNYAQAYFEIQYVRVWSNATTSSGSTGGNGTNSTTGGTAGSGTGGGNGGSTGNNLPSSGSSGSTATSAATSAYAQNAIVAVLLGMFGVVAHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE20</accession>
    <name>M5GE20_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629797.1">
        <property type="nucleotide sequence ID" value="XM_040768364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE20"/>
    <dbReference type="GeneID" id="63683426"/>
    <dbReference type="HOGENOM" id="CLU_1023157_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="29259" checksum="FF6383A547D64814" modified="2013-05-29" version="1">MRSFPGQGIRRPARLTGHCVKSVRKKDGESIPSVPQVSVRVRYRWPVPYLLWIHRPGGNSSYLFDPFFPSYASPTDPTNGLPELETTRGFTPDDGSSSTPRTEGGERQWLELPDVVSLFGDDVWGQGDKDQVAPDGLTGPESVPLTGAEWAWKDAAFQLSDHGQASLNSPHPPPFEAADNGATDSESCPLTRLGTDRSASLDAPPARSPGPQQCGDDSAGSNIGLPDHQPGGPVCGSSSNGDEATCLDGDELDSARTREEQLRVYGRQSYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE31</accession>
    <name>M5GE31_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase C-terminal-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_104926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631931.1">
        <property type="nucleotide sequence ID" value="XM_040767998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE31"/>
    <dbReference type="STRING" id="1858805.M5GE31"/>
    <dbReference type="GeneID" id="63683060"/>
    <dbReference type="HOGENOM" id="CLU_011226_14_0_1"/>
    <dbReference type="OMA" id="FPITRKW"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="102"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="25664" checksum="019AA6C999397474" modified="2013-05-29" version="1">MSKPLVLYTFGTPNGHKPSVYLEELKAAYGPAKIDYVPHSVHIGKNEQKEPWYIAINPNGRIPALTDPNRNNFNVFESAAILLYLAQHYDPEHKFSFDPVTQPDDYSECLQWIFFSHGSIGPMQGQANHFLRFAPEKIPYGITRYQNETKRLYGVLEIRFSQNGGREYLAGPGKGKYSIADINAYPWVNGHAFAGIESVDKWPGVKAWLERIRAREAVEKGMHVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEA1</accession>
    <name>M5GEA1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Osmotin thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_98063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632101.1">
        <property type="nucleotide sequence ID" value="XM_040777506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEA1"/>
    <dbReference type="GeneID" id="63692568"/>
    <dbReference type="HOGENOM" id="CLU_1447259_0_0_1"/>
    <dbReference type="OrthoDB" id="3197284at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067692" description="Osmotin thaumatin-like protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17455" checksum="B0AB38B0E8271AF3" modified="2013-05-29" version="1">MLHTVVPTLLALASLASAHTFTLHNNCNYNVPLYVDSWPGSVAYTGPQPTLSPGQWQSITIPTGWDSRICQNADGGKCWGEDSMTEFTMDSEGLAYYDISNIEAFFIAQQIAPADSSCQTVTCTSANCPCSQAYPVGDESGCRDDAPVKACFGQDFTITYCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEB9</accession>
    <name>M5GEB9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_115385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630032.1">
        <property type="nucleotide sequence ID" value="XM_040769994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEB9"/>
    <dbReference type="STRING" id="1858805.M5GEB9"/>
    <dbReference type="GeneID" id="63685056"/>
    <dbReference type="HOGENOM" id="CLU_043176_0_0_1"/>
    <dbReference type="OMA" id="QPQHQRW"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="63"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="183"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="430" mass="48041" checksum="D9AFC92255B700BE" modified="2013-05-29" version="1">MSGYSQISEMDRREAGTSTSAPLFKSKRYHPYFTPREIAFLSDKQRGKLSYNLEEKTRREACNLIEVIGSRLGFPHRTIGTAQSLFHRFHLFFPMKDFAYWDVAHACLYVSTKVHDTLKKPRDIIVASYHVRFPEEAEKARAKGGEMEINPKNLDIDKLRLVAVERLVLETICFNFKVHTPHSYVIKAGRALGASKELTKLAYKLAIDSHRTVSPLEHPPHIIALASLYLAALLTAFPEHGGVSVIQETEWSKPASTSNGYENRNGRQAPAEPPRRTARDIGEELGQEGRWCRQFGARVFDLQEVAHRLLDLLSSQPAQAIHSLSTSPQTPLTPTSPSPNQPSPIPHGPAPSTTAFTPAHLTRLKIFLREREAAMGPPPIRPQISQEDPSTDYTVGPGAVNILSGNADRNAATEVWNHGREAPSVRFFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEG4</accession>
    <name>M5GEG4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_21480</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630117.1">
        <property type="nucleotide sequence ID" value="XM_040772416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEG4"/>
    <dbReference type="STRING" id="1858805.M5GEG4"/>
    <dbReference type="GeneID" id="63687478"/>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OMA" id="MRELITF"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000013">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000009">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="15">
        <location>
            <begin position="48"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="16">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU03223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="442" mass="48696" checksum="559CE291238023AF" modified="2013-05-29" version="1">MSREIVNIQVGQAGNQVAYAFWQMILAEHGLDANGMYRGDDDQKIARVGVYFSEGSDGKYVPRSLQIDLEPAVTDNIRSGPLGQLFRPDTFVTGDSGAGNNWAKGHYTDGAELIDQILDQVRNQSEKCDALQGFQVIHSLGGGTGAGLGSLLLSKLREEAPDRMLATFSILPSPKVSDTVVEPYNAMLSIHQIIENSDLTFCLDNEALYDAAVRLKNPNPNFGHLNDLIAQVMSGVSTSLRFPGQLNGDLRKLALNLIPFPRLHFLAPAYAPLVPPGSQSFQSLSIPELTASLFDRRNLLVACDPRLGRYLTAATIYRGKLSSREVEASVQQLQAKNSSSFVEWIPDNVSVTLCSVPPIGKKQAGVCLANTTAIQEVFKRTQEQFAAMFKRKAFLHWYTGEGMDAMEFMEAESNVVDLINEYQQYQEASAEEEEYEDEVADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEN0</accession>
    <name>M5GEN0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040771757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEN0"/>
    <dbReference type="STRING" id="1858805.M5GEN0"/>
    <dbReference type="GeneID" id="63686819"/>
    <dbReference type="HOGENOM" id="CLU_032406_0_0_1"/>
    <dbReference type="OMA" id="PRNESWV"/>
    <dbReference type="OrthoDB" id="3067443at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024498">
        <property type="entry name" value="DUF2786"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055592">
        <property type="entry name" value="DUF7168"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10979">
        <property type="entry name" value="DUF2786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23771">
        <property type="entry name" value="DUF7168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2786" evidence="2">
        <location>
            <begin position="108"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7168" evidence="3">
        <location>
            <begin position="175"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="294"/>
            <end position="326"/>
        </location>
    </feature>
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            <end position="347"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU05552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="494" mass="54370" checksum="92DE829F20AF67D2" modified="2013-05-29" version="1">MSEDEDVLVISSEESASEGDYDSDSGDEFVPKGKKGTGANGTSNGKGKGKGKANGNTGKGRARGGKENRSSTDGDVKVATKAEVLSLATDAPPGGRTGNSLTGVDEAVLQRIKKALSLGTHEGTGEAEAKAAMRLASKLMAQHNVNQADVLASEDEEQKLKRAGQSTVAVRSLTGAGVLMHAWSTVVAQAVEKFFDCKSYSMSMGERVDWTFYGLAEQTVAAAYAFEMVYNLILTWSAQNKTAKGRTQKNNYCYGVADGLYELARKDRKEEERRAIQKEKERLALAAKADAEEREREIERLKHRDEEDTKVKVEEVKDEDEKVKPEDEPDEASTVVNDEEPYSDAEDFAGPVNDWDEMGEPGDDFQADFDAEEEDIDGMLRDLDATGHINVKHDPDPVPKSEPKKEEESKPAVVKLEEEDDTPWQSGQQLTLFRHNAASIADDYLRKQKIKLHKLPRVNGPNFSRGGYSNYNQGKEDAKKIDVKRKRIRGVGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFF3</accession>
    <name>M5GFF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation elongation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_73586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFF3"/>
    <dbReference type="STRING" id="1858805.M5GFF3"/>
    <dbReference type="GeneID" id="63691075"/>
    <dbReference type="HOGENOM" id="CLU_002794_4_1_1"/>
    <dbReference type="OMA" id="ATECIRN"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
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        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
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        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
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    </dbReference>
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        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="35"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="811" mass="88545" checksum="523A79633538E825" modified="2013-05-29" version="1">MSFRALLRTYSCRRHTRLLYRSLATAPNHDQSDPWLIRNIALLAHIDSGKTTLTESILHASGHLAAPGTVDTGSTTTDFLPAERERGITIQSASIPVRWKGWSFNLVDTPGHADFGMEVESASSVVDGAVVLIDAVEGVEGQTKGVWAQLDRNGVATRLVFLNKLDRVGASLRGSLLSLLEHRLHRTPLLVSLPLASASSQHYQLAEPGITGLVDLVSLEAWYWDTPDTEAGNAHQITLDPALLSKGQVQAPFEDPEHPLLQEILPARTKLIESLVDGSEPLMDELMRLSDDSDPVSPYLRIPGSSIMPALRSAVLREEVLPVLAGSAWKHIGTQMLMNFVGELLASPVDVEQKEEKREREKGGEALTKAAREEVKVMAWKVGWDKMKGWMTFVRVYSGTLTRGATLWNTTTGEKERVAKLMLIYADQSVEVDNLPFGSIGVVLGLKHTRTGDTLVSNLRTRAPLRAITPPPSVISASVVPATRNDTFPVLEALASLSRTDPSVRISEDEEEAQTLVHGLGALHLEIVESRLRDEWGVACAFGRRRVSYREGFFGLEPRRVEEHWQRDAGGKRVGALVVLNVRSLKEQEGEKDDPQWTGNAVVYNNEPLAPPAHESSSLDPLFHVAQGIQTALTGSPHSSLPVIGLHITLESVKLDYGSPPSVAASAASFALRKVLKDAGRGEIREPYMAVTVHVCEEDVGKIVKDFGEKGGEVQELGANAEAEDTYPTEGIYVPPAILTPSAMPSEDGQGTIRMKRTVQAVAPLSKLLDYNSRLRALSGGQASFEMAADGFRTVNEARRLEILREIGRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFM2</accession>
    <name>M5GFM2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20829</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631127.1">
        <property type="nucleotide sequence ID" value="XM_040772102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFM2"/>
    <dbReference type="STRING" id="1858805.M5GFM2"/>
    <dbReference type="GeneID" id="63687164"/>
    <dbReference type="HOGENOM" id="CLU_002572_0_0_1"/>
    <dbReference type="OMA" id="KYLVNCM"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF41">
        <property type="entry name" value="CHITIN SYNTHASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="822"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="879"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="13">
        <location>
            <begin position="242"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="977"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1117"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="977"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1161" mass="129273" checksum="28344FD80A80B2B8" modified="2013-05-29" version="1">MPNPNFFPLPDSSRPSLPMHTRQPTRQGGGGSIRRAKTLVKPERSVAPAPLINPPTIVGSQAVKLVDPADSWDAWRIFSLLITFWAPPIFLKWARISDTPSQQAWREKVALCFLALVLGAFVGFVTMGLDRVLCPTSASIDQSRYSKLGSTPGTLGVEGWEYNISSSTPPANFDFFTIAAQEPGQDITPYFQRGYANFPACQSLSARFANMNVCNGTTCPMGDPSQPATFQMYNLQNTSLIVGYDWDQVANLTDYMVIDGDVLNMQPYMQSNPNPITADPVDAAIRSVLRTRPGSSGRDATMLFYSRPYLKSAVPCLQERYYAGSIDKLTAGCFISTLFLYISLVMIMGIVLTRFGMACIFNWFISAELVKPPRNLSRTVISPAVMPEGANVTVDNEMGTAPWTARAAKKSGKLTKRSSKTSRPSSPSLRGPAAAAAVAAAQPLIQATQIGAELYTVCLVTCYSENEHSIRGTLDSIAGTQYSDKRKLLFVVCDGMVTGSGEKTSTPDICVGLLEADERFGDPMPLLYGAIGTGAKRENRAMVYAGHYVYGKHRTPTIIVVKCGMEKEMNGPKPGNRGKRDSQLVLMNFFQRVTYNDRMTPLDFDMFRKIQVLMGVTPDFFELCLMVDADTRVDTMSLKQLVNCMHHDRMIMGVCGETRIANKRQSWVTMIQVYEYFISHHLAKAFESVFGGVTCLPGCFSMYRLKARKAQDDDWIPLLCKPEIVRDYSQSDVTTLHQKNLLLLGEDRFLTTILLRTFPSRKMIFCPQAKCHTVAPDEFKVLLSQRRRWINSTVHNLMELVRVRNLCGTFCFSMQFVVFMDLLGTAVLPVSICLTYALIVNMVLEPPNSFEKAIPLMLLVAVIGLPAILILITTRKFIYVAWMFIYLLALPIWNFVLPVYAFWHFDDFSWGETRKVEGELKSLGHGGGVAGAYDGTSVPLRRWEDWERSRLRKLRRDERRRREFERMQFGKHLDPFSTSHSMNGLGNGSPFSGSPFQGREVMDDGYDSAMSDTVSVVSSNEDDHWGTQIGGYNENSAQYPPPPITLGADMDDDFLREAKTVGKDEMEAMLEEGFDDRPTNDFSPAYRVPPVPAMDSKYFVQAPPAAQRYRLEDSPAYRPMRPVADSSAVRSQGHARQRSGAAGKPINYGPLGPLDPGGGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFX6</accession>
    <name>M5GFX6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_47812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631427.1">
        <property type="nucleotide sequence ID" value="XM_040774785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFX6"/>
    <dbReference type="STRING" id="1858805.M5GFX6"/>
    <dbReference type="GeneID" id="63689847"/>
    <dbReference type="HOGENOM" id="CLU_000134_18_2_1"/>
    <dbReference type="OMA" id="HVVNLCG"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="144" mass="15270" checksum="6BAE1A10A67A2AD0" modified="2013-05-29" version="1">MGSVELHVHFVFGSHYAASKGRYEIGKLLVAAGADINAKDKALQLPLHRAATTGSIAFINVLLRAPPGSAKPRLNTGDRMGNTPLHLAMESAHAEAAVTLIEAGADRSRINLDGQTPEHLEGVGGQEQKRAREYVVSRVGPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG88</accession>
    <name>M5GG88_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631957.1">
        <property type="nucleotide sequence ID" value="XM_040772003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG88"/>
    <dbReference type="STRING" id="1858805.M5GG88"/>
    <dbReference type="GeneID" id="63687065"/>
    <dbReference type="HOGENOM" id="CLU_1378074_0_0_1"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="198" mass="22388" checksum="5F44BC69279A41AD" modified="2013-05-29" version="1">MNKRLVAIARFLLEQHAQVDFRGKDNATPLSLAYEWGHTDLVKLLLKHGADPTSIVLQAAGTNSRIDELMQIAKRDWTGSATKPPRSCPCFSGKTLAACHQARDHAYPLDFLCPCGKGMSYEDCCLLVASRNWVERWVEEDGYAFIKPVLIERRFSEDSQEVKQISRQLIARLEDLCKEGFIDPSFLSVVRHIKSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGH0</accession>
    <name>M5GGH0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_61974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632367.1">
        <property type="nucleotide sequence ID" value="XM_040775685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGH0"/>
    <dbReference type="STRING" id="1858805.M5GGH0"/>
    <dbReference type="GeneID" id="63690747"/>
    <dbReference type="HOGENOM" id="CLU_051989_0_2_1"/>
    <dbReference type="OMA" id="VPIDRYK"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008265">
        <property type="entry name" value="Lipase_GDSL_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01098">
        <property type="entry name" value="LIPASE_GDSL_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="28714" checksum="CB100FA43B8F13EB" modified="2013-05-29" version="1">MAGNMDAIMLIGDSLTQGGWEPGGFAQRLAYRYARKMDVLNRGLSGYNTEWALEVFKQTFPRNDGGGGGQKVKLLIIWFGANDAVLPPKVQHSPLPKFKENMHTLISLLRSPSSAYHSPHTRLLLITPPPFSSLQRGSILASRTPPEPLDRDQAVTRAYAQAVRELGEEQAIPVVDMYTLLWEGAGGKEEGLDKWMQDGLHVNAAAYEVLYDHIVSTVKTHYPELHPDNLPFVFAPWDEMIRTTDVKGTLQSRYKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN39</accession>
    <name>M5FN39_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623673.1">
        <property type="nucleotide sequence ID" value="XM_040774174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN39"/>
    <dbReference type="STRING" id="1858805.M5FN39"/>
    <dbReference type="GeneID" id="63689236"/>
    <dbReference type="HOGENOM" id="CLU_2533582_0_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="9150" checksum="F828D49BE7352751" modified="2013-05-29" version="1" fragment="single">KPAKEGYMWWATEGCHNINRYSFGEGSPAAKDEGAPEGAFVNEYPLSKYHELAERLPLSTSSFANSTVSETPPLSLRASCSRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN46</accession>
    <name>M5FN46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_112427</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623708.1">
        <property type="nucleotide sequence ID" value="XM_040769411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN46"/>
    <dbReference type="STRING" id="1858805.M5FN46"/>
    <dbReference type="GeneID" id="63684473"/>
    <dbReference type="HOGENOM" id="CLU_023205_0_3_1"/>
    <dbReference type="OMA" id="IFMRHIF"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT96810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="277" mass="30821" checksum="69F5007598E29F74" modified="2013-05-29" version="1">MAMPIYTMLDGHTIPQLGFGSGTAHYKQNAVKPILMALQANYTHIDTAQIYGNEDTVGDAIAQSGIPPEKLFVTTKLWDLPEGKTIEDSLKESLTRLKMDYVDLFLMEDVKDAGLSRSIGVSNFEVQYLERILKIAKHKPVVNQLEFHPYDYAQLLPVLKLQKEHGILTESYGGLTPLTKKTDGPVNSVLKELAAKIGGTETQVLMKWLEQKGVVAVTTTSKEERLKEYVDVYSLPDLSEADVKAIDEAGAKLHYSWLALYLEGEKKESTGKEGWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP16</accession>
    <name>M5FP16_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_18225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625043.1">
        <property type="nucleotide sequence ID" value="XM_040771344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP16"/>
    <dbReference type="STRING" id="1858805.M5FP16"/>
    <dbReference type="GeneID" id="63686406"/>
    <dbReference type="HOGENOM" id="CLU_409385_0_0_1"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF2">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="592"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="671" mass="73904" checksum="128DA6F3388A0D76" modified="2013-05-29" version="1">MSTNRPLTNITNTPSRRRRQKRDSPPTLKLEDWLHISPASSSPPDLAAASSSQSRNSAKLQSRTPPHPHSFSSLSPPLLLHANPFIDAEHTTDEWRNIVSSFGLDSHARGPYAVSLSIPTSGFPDPTFTSDRVSESSSPKLFSYDDDFSSFTPTYLTQDSPDSPLFHQLEGLPDAVYEPPDFAFSWSDSPRTSSSTSTSPVPERTRRILHSPNPFLGNFEMRSVSPVIPEARPLVEVSKPISKVQTTVIAVAETEVQVTPLASNCGHSRSSSSSSHRSGISLTAEGYLSVIPSSLKRHERVNTPVSALRSTAEWEKEDLDYVPPSPAPSSALTSLSSNDDSPENQTTSVIKRPLPYAIEEPSSPPNKRFRLSICAPTPIIAAPPIIPATSTKSRRKRLSSSSTTTSTSSRPARTWTSSTLTSLTASQHSVQGDTSSGTIKTTSSSVGSDDPHPATISSESAEEPSSPVPAERDPAIFDETGAYIRRILPPDVPIVEDFSLFYRRWPMSSLFAREDEIGHRALRQIGMTVKQPQGGWTYNEPRSVYDLYTPRLVKGMGKDKMAMCPVCIEPISRGGEGKRVAYKTKVSAYTFRTTERSVNTKNMKDTMREGRCHRCKKWIPLDGVRSGDVKVREIFWWKHAAKCHGEEDPVEDTHPLFEDALFHAYRSLSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP19</accession>
    <name>M5FP19_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623621.1">
        <property type="nucleotide sequence ID" value="XM_040774208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP19"/>
    <dbReference type="GeneID" id="63689270"/>
    <dbReference type="HOGENOM" id="CLU_762956_0_0_1"/>
    <dbReference type="OMA" id="MHEKNVS"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="363" mass="39820" checksum="3494D22CF0F2DDD0" modified="2013-05-29" version="1">MAMVRAVEEAYGSVENVIFGRDPELLTYAPYLWVFFASPSSLTEIGKGTTLEVSLPPVLPPSPGGIPLSSLSGLLRPSPDISFVRSETTDSSPDSSPESSLDSSFESPSEPPLPDKPDNAVLRITRHTGLPGGFITPKAQAKSNRQMSRLKTLDMFRSLEGWQGFGPTHTTTVVSDQTAETTIDASTATVTEAPSGHVDVVKAAREALHKIRQASKKEAERLGWDTALPVRQVPAEPAPPEAAEPAAAPMEPTKEEKPKKEKVKKPSVDASHLGAFLPPQERLSHRSKKALATRLAKLQEDRSVLAVQEQKAKEEKEEEEEKEREEGRRKVQERREMLLEKIRIAKEKIEAKEGRREEASLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP45</accession>
    <name>M5FP45_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625098.1">
        <property type="nucleotide sequence ID" value="XM_040773792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP45"/>
    <dbReference type="STRING" id="1858805.M5FP45"/>
    <dbReference type="GeneID" id="63688854"/>
    <dbReference type="HOGENOM" id="CLU_013985_42_1_1"/>
    <dbReference type="OMA" id="MEQPMAL"/>
    <dbReference type="OrthoDB" id="10264707at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052742">
        <property type="entry name" value="Mito_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE ACA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="72"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="261" mass="29316" checksum="6D8CB7450EE6EC99" modified="2013-05-29" version="1">MSAYGTIPRPAGVIPQLNPLTFAVTRKGSQSPMGFVTVVPVKRSTVPDALFEHLHMLFNGVVEEGRTYPQEFELTEQSFEDYYFSYDCFIGVLDKGFAPTRTDGSYWDPKAEAWIRTDAETIDDIVGKDVKDYKELVVGMYYVKPNYPGRSSHCCNGGFIVDPYHRGAGYGYLLGMSYLYFAPRLGYLASVFNLVYSNNVASLKIWDKLGFTRAGLIPKAGRLRKNGDDGEEFVDAVVFWKSLVEDDVWTKRLARTEGAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPC6</accession>
    <name>M5FPC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_57484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625338.1">
        <property type="nucleotide sequence ID" value="XM_040775448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPC6"/>
    <dbReference type="GeneID" id="63690510"/>
    <dbReference type="HOGENOM" id="CLU_089014_0_0_1"/>
    <dbReference type="OMA" id="ESTYHRK"/>
    <dbReference type="OrthoDB" id="17066at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="232" mass="25808" checksum="D02E185BA9F3B80B" modified="2013-05-29" version="1">MSRLASLHGPSTPSSSPRNVSRGSPVPDSPQAAPIESPFHRKLRSSLRDIAGAIEGWDEMVLGEGLRAVKGVVDNGTALDNALASNPNHRSFIATPRIQAINAHLKTLNALCWRLEKQFRLLTMSVDALESLIMSTAAARGPLFLRTPVWISWTPEHFLNALLSLPRRYHQSLITISQCVEKLKDPDISWDEGKDAVQTWADQREIRAKADELDWTEIEEIFVVEVRGWADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPC7</accession>
    <name>M5FPC7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623871.1">
        <property type="nucleotide sequence ID" value="XM_040771415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPC7"/>
    <dbReference type="STRING" id="1858805.M5FPC7"/>
    <dbReference type="GeneID" id="63686477"/>
    <dbReference type="HOGENOM" id="CLU_1250640_0_0_1"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="221" mass="24817" checksum="9E7146E96DCCDD96" modified="2013-05-29" version="1">MKVKEEEEKAPAPPELAQPTCAASGGWFGCMWGMTAATATAAEEEEPSATLDNDQRQELYNVIEYSDKDVIPQSINLLQDVMKMCMSACLTQGTFTLWPGGSDMISLMFDSLSSDLIQQPENMEFVLALGGLSVYDATLPNSVYPQIVCIKEQQPKAIDLKEQEEASNQLSKVTDTEDPFLLSKFEQNPLDKRADSTLTIRMWDMEIIYHWGYVQAIFKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPL4</accession>
    <name>M5FPL4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_101721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625543.1">
        <property type="nucleotide sequence ID" value="XM_040767580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPL4"/>
    <dbReference type="STRING" id="1858805.M5FPL4"/>
    <dbReference type="GeneID" id="63682642"/>
    <dbReference type="HOGENOM" id="CLU_476494_0_0_1"/>
    <dbReference type="OMA" id="REKWITI"/>
    <dbReference type="OrthoDB" id="2447803at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="63698" checksum="904D6AC3FE981165" modified="2013-05-29" version="1">MHRALQIPEILQLIFSHLAHDDLAILLRTSGFFFFPSASQLWASVDTEALMCLVNLFLDTEEVKNPTATSKRHYSIASRMRRFQMYAPLIQTLDLDLTSGVDEEGESEELNDDYAHLSLTAIATLTRTSALLPGLRSLHYTTLEAEHLNNVLLFLAPSLEELYVKTFHCDDQYWGNAEADWALPVGCLLEALPRLCPRLRKLSLAAHMPRTSIHLSTVISLVTKLAFLECFECDFIGLHPTLLGALARRPALQELRVGYYNVDILGEQVAYQLVCHPPFPALRSLHLSANQHIAPMFLKLIPPQLHSLTLDIGAEPFTPEALAYIASMVAAGQPHLRALSLTCRDFDYGADTSVDFDVFAPLLQIKSITQLELSYLAATRLALADTHVAAIGNAWPALEVLNLQWNDRLATGSGGLADESALTLSALAVLTTRCRRLERVELRALNIYHIPPPPPIAPVQAHVELRLTHGRVHVQPELLAAFLYTLWPRIQMTGPFISLPHAPAQVTADAVPLPPGTTDTDRDREKWITIRGMIASMRCQQIMEARKGATPERVRESFEPKYRDHLLSPATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPR7</accession>
    <name>M5FPR7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_96458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625628.1">
        <property type="nucleotide sequence ID" value="XM_040777373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPR7"/>
    <dbReference type="STRING" id="1858805.M5FPR7"/>
    <dbReference type="GeneID" id="63692435"/>
    <dbReference type="HOGENOM" id="CLU_025149_0_0_1"/>
    <dbReference type="OMA" id="PSSFMFR"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="9">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="335"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="349"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="528" mass="54941" checksum="2F201FDF7574C301" modified="2013-05-29" version="1">MSATPGLSPARAVTRTVAILKPSAVKHRLTIEPRLIEAGFEIVKERQVEFQPDDVALEALFGRDGPSLADGPVWVYVLERRRAVEVLNTLMGPEDPEIARNDAPKSLRAIYGRSLDDNAIYGSRSTDDAERQIAILFAGSPPFRGADLASELPLPASESDFSLNQSTHATPDRSSSHRVLADPASPESLVPSNYSGSQSTSPLRNGRAAMLPRQNRASLLRAGSDQLLPATRPKRIHTTDDDPVTFADVPGHKYRSVSIVVASTAPPVTAPRQNKAAALRAGLQIAPTTARERKPVQFDGTPGHKRSQTFSVVSTKPPAVAPRLNRSAALRLSTGGVPGAAAPAPPAVKPSAPSRGRSSSSMGVASNTSTTPSRSSSAVRPPSSVGSTGPTPSRPKLAGRTGSAAPPSSFRGMPTVDVPETPASRPGTAPGTRPSLSARASSASLTSGKTKEEEAPAKAPSRPASSLARPPSITPRMNRSASLRASMGGAGIMTPAQAKSKVAPSTSGKVVPKKPASSDRQGPKSIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ48</accession>
    <name>M5FQ48_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623622.1">
        <property type="nucleotide sequence ID" value="XM_040770899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ48"/>
    <dbReference type="GeneID" id="63685961"/>
    <dbReference type="HOGENOM" id="CLU_1686513_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="156" mass="17325" checksum="88C8181B88EF51A6" modified="2013-05-29" version="1">MSVATGGLALILIAGGAIILAMVVSIFFRLFRRSQNPTPDGRALEAYPPVQSQYLRSQYGQYPQYRYTPQVALALRDWQRQPPVHRIPEAPAEGEQLPSYQDAGKDVVLPVLYSNAPPALPPRRISQEEVAVPPEAMMRPRPPPPGYETASGWRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ62</accession>
    <name>M5FQ62_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624441.1">
        <property type="nucleotide sequence ID" value="XM_040771365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ62"/>
    <dbReference type="GeneID" id="63686427"/>
    <dbReference type="HOGENOM" id="CLU_1120156_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067045" evidence="1">
        <location>
            <begin position="25"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="27314" checksum="53CCBB47A0DDECB8" modified="2013-05-29" version="1">MLPAQLMQAMHGFTMICLTTVLEGLIEDDCKPIFAVQLSILLTALDVFGSGGLHVQSWGTQTAALIEWSGIGHCFLITLHEVDSEDCCSTQAALSTYEWHSNAHVLYDEYPESMALCGLSKSFFSCTQHSFVRIMCTVMPGKHFVDLLHKISGSSDPDYIYISFSTAPPMEDGRSLACISFKWECSMGFSKSSVHYSSSDTNPSVVTFLEIDTLEEDMMKFKYCASAILAMNLAASMAQSCLTAFMPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ82</accession>
    <name>M5FQ82_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623697.1">
        <property type="nucleotide sequence ID" value="XM_040769409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ82"/>
    <dbReference type="STRING" id="1858805.M5FQ82"/>
    <dbReference type="GeneID" id="63684471"/>
    <dbReference type="HOGENOM" id="CLU_342890_0_0_1"/>
    <dbReference type="OrthoDB" id="2576334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="611"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="666" mass="71019" checksum="7C5CFBED6A0F3AD7" modified="2013-05-29" version="1">MSALYPYTISLVSSSPTFIFQPFRDGFYESEGDPAGGWRGTFTNITTWPNPSTQNIGSGVPFRQTYLDGANLTLAFEGTAVYFCLTAINAAFDFTVDGSPVVTTKSPPADPGCDGTGAEIMAYTSKLEYANHTATLQVNSRGQVDFRFFGGFVTIGLAGYEPFQEGWYALQGDPTGGWRTSFSSLTTWPNPGLGNFGTGVPLRETYLDGANVTLQFEGTALYLCLLLTESAYTFTVDGSPVSTTGSAEDPACASTAAHLMAYVDGLTYGSHTATLRVNSQGNADFQFFGGVVTVGLNGTNPTIERIDDAEVGWSYQPAGVWIFSTPATATNAANDYAGTRHWMCSYGPAFLASYTFNESAAVQLLGMLDLNMGPFTIQFDGQSYVYNGSDLWHEPQQVLFFKAGLDPTKEYTITLINYDPAAPNAQQPVGPDFYPCASVDELILTKVTPGLPSTGGGGNGTAGAGSGGDTTGGAVGGATGNGSSRVGAIAGGVVGGVALLCIALFLLWFFWWRKRSAPLSDSSRSEIDPYPQNEANEEAIPYPLPRSMYSAAPTSESALPGLDLHKPEDGNYIQSPLQLLASPVPVQSPTEHRDTKQHLNNMSMRQPSAPISLSIQQSSATSTSESTPYQVATTQELVGILNQRLREEYRAENDMDPELPQYAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ85</accession>
    <name>M5FQ85_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_119248</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT97573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040770753.1"/>
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    <dbReference type="STRING" id="1858805.M5FQ85"/>
    <dbReference type="GeneID" id="63685815"/>
    <dbReference type="HOGENOM" id="CLU_007406_0_0_1"/>
    <dbReference type="OMA" id="HVQCFIL"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
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    </dbReference>
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        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
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    </dbReference>
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    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="647"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
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        </location>
    </feature>
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        <location>
            <begin position="719"/>
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            <begin position="837"/>
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        </location>
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        <location>
            <begin position="960"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
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            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
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            <begin position="839"/>
            <end position="859"/>
        </location>
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            <begin position="870"/>
            <end position="900"/>
        </location>
    </feature>
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            <begin position="914"/>
            <end position="935"/>
        </location>
    </feature>
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        <location>
            <begin position="978"/>
            <end position="989"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQY8</accession>
    <name>M5FQY8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067208" evidence="1">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="182" mass="19709" checksum="60C9840C4E667E3A" modified="2013-05-29" version="1">MLPVTSTLAIVLLASTVFSVPISNTHTAPSSGDANTLQTRDWDQAELDKRWLGFFSSTAQTIRRVATSVNGVATSARLGFANGLQAGINEGVKAGVHNVVKNAVKGTAQKAATTSLQKVLTSQKVINALRKARVEGTRGRRRGVQRDLEGLEDDEILARELLGNEVERRMGAREFEHLDMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR70</accession>
    <name>M5FR70_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_24634</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625011.1">
        <property type="nucleotide sequence ID" value="XM_040773766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR70"/>
    <dbReference type="STRING" id="1858805.M5FR70"/>
    <dbReference type="GeneID" id="63688828"/>
    <dbReference type="HOGENOM" id="CLU_035750_3_0_1"/>
    <dbReference type="OMA" id="KQHLFRH"/>
    <dbReference type="OrthoDB" id="429533at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000005">
        <property type="entry name" value="Proteasome subunit beta type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="11">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="275" mass="29602" checksum="3BFF1D2B69F57860" modified="2013-05-29" version="1">MSVDVFRKGGFDFSNARRNAFLEAKGLPLPKATSTGTTIVGCVYADGIVLGADTRATEGPIVADKNCEKIHYITDNIRCCGAGTAADTEYTTAMISSNMALHALSTGRQPRVVTAMTMLKQYLFRYQGHVGAALVLGGVDPTGPQLYTIHPHGSTDKLPYVTMGSGSLAAMAVFESSWRANMTREEAVQLVAAAISAGIFNDLGSGSNVDVCIVTKDKTEMLRNYEMPNQRVQKERQYGFRRGTTAIKSETIRSLITSETVVPVGQLVTDEMDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRC2</accession>
    <name>M5FRC2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin cytoskeleton-regulatory complex protein SLA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_119198</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SLA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624397.1">
        <property type="nucleotide sequence ID" value="XM_040770737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRC2"/>
    <dbReference type="STRING" id="1858805.M5FRC2"/>
    <dbReference type="GeneID" id="63685799"/>
    <dbReference type="HOGENOM" id="CLU_006319_0_0_1"/>
    <dbReference type="OMA" id="FMAQGED"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11773">
        <property type="entry name" value="SH3_Sla1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.700">
        <property type="entry name" value="SLA1 homology domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056996">
        <property type="entry name" value="PH_SLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035800">
        <property type="entry name" value="Sla1_SH3_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24081">
        <property type="entry name" value="PH_SLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="71"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="315"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="375"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="469"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="668"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="583"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="702"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="746"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="825"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1137" mass="122118" checksum="E956A3F16F3CC5A3" modified="2013-05-29" version="1">MSPLALGVIKALYDYEAQSDDELTVKEDDILYLLDNSDSEWWKVRHKTDSSDDEGPSGVVPATYVEEVQPVGIVKALYDYEANANGELSIKEGDVLIMYEKEDDWILVKGDQRDSKVGFVPATYVEDHNPDEAPSTEPTPAPEMPASNYVDPQERVLASVAKASPSDNIETWPVTEIDSKGKKKKGTLGIGKGNVFFASESDKTPVQQWKAGDITSVIEDKPKHVMLIIGGVNAAELHFNAGSKEIAQAIVTKAATSGGALQSGSSNIHPPKPEDEAEPFEDYAVEEGKPKKNGVHWAPSPTSPVGVSFPTPDPTEGESAIATYDFEAQSEDELTVREGDALVVVDRVSSEDWWKCRNDRGQEGVVPRSYVELEAREGAARAAAEAEEAEERARQEEAAQAQAEAESEAEAAAAVARAARERELADEQRRQAAALKRREDEKKLIEQRRIKEEDRARRKAEEARVIKAAEARRAEEASRAQTSTRRRDDGRPRSKSGQSERSKPTNTRIWHDRTGQFKVEAEFLGHNNGKIKLHKINGVIIEVPAEKMSEEDMAYISDIMNPRRKVSIRADSDDNIPLATIADQRKQPEPKDRRASIAKQGSMSKKPTVDWFEFFLNAGCDIDDCTRYANAFERDKIDQSILGDIKPETMRALGLREGDIIRVAKAIEEHRFSPKPPTATKDTAGAEDQMRRDEEYARQLQAEINGNRRSSPSATSPPNLFTGPGGALKTSQRRGRPQTKTSAPLAVDVSSIASASDRLTQSPAAASPSLIPSASPPAPAPAPKAARPLTPAQSGFDDNAWEPRPLTKPAPEAPAAPMIALSLPPQVPVPPTPPASAPSAPPPPPPAPTVTQTLAGGQIARPQTSSAALTPTQTGEFELLAKLSQMRPPSAPVSQMTPIPFTGTPPYQAGLGMGASPIPLAQLQAQQTGMYFQNNGPRGPLVPVPANQGLLNPLVPTNTGFAGFIPTRPTSTPIMQPPALMSQPTGFPSMAGGIRPQPTGFPTFTAGTLPITGLQPQPTGFSPVFAQVPQQQFTTSVTPNQFIPAPAPLPPSQPAANHSPASVFASMKSGSFAAGASDAQPADKYGALRSPNGGVGQPYQGFLTAQPTGFVPNSGTWTVPTNTSGYGQPGFAGYQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS26</accession>
    <name>M5FS26_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_36407</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625481.1">
        <property type="nucleotide sequence ID" value="XM_040774408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS26"/>
    <dbReference type="STRING" id="1858805.M5FS26"/>
    <dbReference type="GeneID" id="63689470"/>
    <dbReference type="HOGENOM" id="CLU_162151_1_0_1"/>
    <dbReference type="OMA" id="VGENMQK"/>
    <dbReference type="OrthoDB" id="274922at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.810:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="14">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT98583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="8897" checksum="4EA0520975B228E2" modified="2013-05-29" version="1" fragment="single">GGMGGGMPAQSANLDVAVAELDMITDVFNRIVSSCHSKCINPRYAEADLNKGESVCIDRCVAKFFEVNKKVGERMQTMGGAAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSK2</accession>
    <name>M5FSK2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_109156</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627333.1">
        <property type="nucleotide sequence ID" value="XM_040768825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSK2"/>
    <dbReference type="STRING" id="1858805.M5FSK2"/>
    <dbReference type="GeneID" id="63683887"/>
    <dbReference type="HOGENOM" id="CLU_1669341_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="158" mass="17653" checksum="040F55B0D76F1DD7" modified="2013-05-29" version="1">MDNSPAGTHIIIPVEAINTSSKLWGPNAREFRPERWLEGGKDETKNGLAESASSISGRGHQKVLTFGDGPRICLGKSFALVEMKCLLSKLVRQFVFTPVLSDVRVGEWEHTAPSAFDHKRTVEQEESRVWYCVFLKLNESNQTTHKRTTKSLIVAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FST7</accession>
    <name>M5FST7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the VPS35 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625911.1">
        <property type="nucleotide sequence ID" value="XM_040773547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FST7"/>
    <dbReference type="STRING" id="1858805.M5FST7"/>
    <dbReference type="GeneID" id="63688609"/>
    <dbReference type="HOGENOM" id="CLU_005836_0_0_1"/>
    <dbReference type="OMA" id="YIRSREY"/>
    <dbReference type="OrthoDB" id="10258141at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030906">
        <property type="term" value="C:retromer, cargo-selective complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.660:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005378">
        <property type="entry name" value="Vps35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042491">
        <property type="entry name" value="Vps35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="939" mass="104813" checksum="232D197C2AEA8530" modified="2013-05-29" version="1">MSSAAATGAGGPGVDGDAGSVIGGNDEGKMLAEALATVKIQLVQMKRCLENDQLMDALKSASTMLSELRTSSLSPKQYYELYMAVFDALRHLSNYLFDAHVSGKHHLADLYELVQYAGNIVPRLYLMITVGSVYMSIPDAPVKEIMKDMMEMSRGVQHPTRGLFLRHYLSGQTRDHLPIGNSEGPEGNLKDSIGFVLTNFIEMNKLWVRLQHQGHSREREKREVERKELRILVGTNLVRLSQLEGVEFETYRTTILPSILEQVVNCKDVIAQEYLMEVVIQVFTDEFHLHTLSPFLSAVAQLHPKVNIKGIVIALIDRLASYAAREAENEDPAETKRQEEEAAHRLAEKVKDQKARARAALEANGHGSPPPAVQAGANEWGGSAVNPEEKPQPAPPVNGSDAKSDKGKEKEAPPAATRKFRGIPEDVKLFEVFWEQIVNLIKARPDLSITDITALLVSLINLSLSCYPDRLEYVDQILGFARGKMQEFQESPDLLIPATTANLLSLLLAPINSYQSVLTLLALPNYTSLLQLQAFTTRRAIAHAIVSSVLKNETVIDTPEDVAGVLQLCHVLVKTQPDAIPSPLAKQMGAGRQGVDVEEMAEEQGWVARMVHLFRAEDLDVQFELLQEARRHFSEGAERIRFTFPPLINAAIKLARRYKRVEGEDDEWTNKLTSLFKFIHQIISVMYNRVEASDISLRLFLLAAQVSDDCGFEELTYEFYVQAFTIYEESISESRAQLQAITLVMGTLQQSKVFSTDNYDTLITKAALHGAKLLKKSHQATAVGLASHLWWQADIPKHAEEEGESHEPLRDGNRVLECLQKTLRIASSCYEEIISVQLYVQALDQYLYYFDRDVEAVTPKYINSLVELITSNIDAISSSDFHPTSRAPPGLIEGVHTADMITRHFRNTLLYVRSKKESGVGRWSEVDIAGALLKMNVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTA2</accession>
    <name>M5FTA2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626151.1">
        <property type="nucleotide sequence ID" value="XM_040773425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTA2"/>
    <dbReference type="STRING" id="1858805.M5FTA2"/>
    <dbReference type="GeneID" id="63688487"/>
    <dbReference type="HOGENOM" id="CLU_019611_0_1_1"/>
    <dbReference type="OMA" id="MDWDERE"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055225">
        <property type="entry name" value="DNAJC11-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22774">
        <property type="entry name" value="DNAJC11_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="31"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="725" mass="80919" checksum="023A3A023B229B7C" modified="2013-05-29" version="1">MDWDEREDEDYDNVEEHVYGQETGEVEEEVDYYALLNVEKTASTREIHQSYRHLASLLHPDKHPPKHREMAEKRFQDLTTAYTVLTDENKRHVYDTLGVRGLKFNWAVTQPRRPAEELRQDFEHFNNGMRWQQAQASITNLVALDARGIFQQYVVVSAFPAVHESEDADHGEDEHEEAVEPEETPEDSAPEETPKSDEEVKPAKIKLDVTEKPKETKEQEIELEVIEPPLLSLSRLQLSHSTTFPLAKRLSIRLLATAGTRDDRGTANFMGTAKYQFPNGLTAEVGSNLIRNRVPFAHAAFELPYLKQTRMTVRATCPTLLFPPPISLSFSRRLSSRWESSLALSTGTWVLPFWPPDQTKYALDLDESKENVRIVNMEDDPELEPGWKRMLLSRAASLALKFGVKQRPRTLSLTFTKINKETGSVDQASTLYAVLLEESNPHLQASWGGTIPARRLIYTGLAKLLPGETEAKVSDESKHANTLAPNKIAWNFMVDLGLLTGIMTVTTVSGQTGPASWGVSVDLGESGVWLRIKVGVRGQKITVPIWLIDEPDLLFGLSTVGVVATTVLSCFTASELWHLLDKRRRLKALREARAGQLAKKRQEAEGVHQMLKELVERSLASKQTTDGLAVLAASYGPAGAFDPATESAVPSPIDVTLPIQALMSEGHLHIAGGRSKSGLLGFYDAFPDLKKALRITYQYEGKKHEVTVGDLEEVSAPSEAHLIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTE7</accession>
    <name>M5FTE7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_110052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626231.1">
        <property type="nucleotide sequence ID" value="XM_040768989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTE7"/>
    <dbReference type="STRING" id="1858805.M5FTE7"/>
    <dbReference type="GeneID" id="63684051"/>
    <dbReference type="HOGENOM" id="CLU_008455_13_5_1"/>
    <dbReference type="OMA" id="VFMIWGK"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF160">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="525" mass="57701" checksum="059BAC2DC86D1DF7" modified="2013-05-29" version="1">MDLLTYDEYSRHLVHSHAHEGDIPGSVYLKAEDGDDTKGTYGQAIFPIPSDDPNDPLQWNNTKKTIILIICCLYSFISNSATLGPSVYIGIWAEEFSVSPSTSSGLLSYPNLAYGFGSLFLVPLYLKIGRRPVMLGSLVVFLAGLIAASQCTTFNSLMISRVIHAFASGVVRRFQFSWLTTYSSCTSVASALVSLCMGATGPLYAGYMLAGYMLAGGYSWRLYFYVEIAFAGALLLAAFFFVEESAYKRATPQEDHAEKPNNGTVDSPTKEKPGDTIHSVAVPMRKSFLQTLNPWSSIDHEVSFLMTMIRPFTYFVVPAVFWVITTYGICIGLGAVTFNYTFPLKITAPPYNWSETNSGLIAVASIIGYSLATLFASSSDAVAPYLTRKNDGVREAEMRLSVMLPAMLIAPAGLVLRGNGDMGFLLLFLVYAHSIDSYYANTSEMLIAMNLGKQAIAFGMAIYLLDWILQYGFAVMIAGVFTGLLLANNLLLLVFMIWGKRIRVWTSKTWLAQVHKSTITQVMGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTG6</accession>
    <name>M5FTG6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SIN1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_118096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626261.1">
        <property type="nucleotide sequence ID" value="XM_040770525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTG6"/>
    <dbReference type="STRING" id="1858805.M5FTG6"/>
    <dbReference type="GeneID" id="63685587"/>
    <dbReference type="HOGENOM" id="CLU_007847_0_0_1"/>
    <dbReference type="OMA" id="RINDDAY"/>
    <dbReference type="OrthoDB" id="241990at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031567">
        <property type="entry name" value="CRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008828">
        <property type="entry name" value="Sin1/Avo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031313">
        <property type="entry name" value="Sin1_PH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335:SF1">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16978">
        <property type="entry name" value="CRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16979">
        <property type="entry name" value="SIN1_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRIM" evidence="3">
        <location>
            <begin position="546"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="SIN1-type PH" evidence="4">
        <location>
            <begin position="874"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="996" mass="107548" checksum="9791C6A8E529FDE5" modified="2013-05-29" version="1">MSLISDPDYVIHNLRLNYLRHVDDPYGPRIISISQKHCANPLVVATGLDDPDLWPELRVPSSPKLAAVDASLANGSLSTTPPVSSGMGDGPNFGATGLRHSETIYGSSRNGAAGMRVSGRFTSNTPRNRGLGLEAAELSTSVGSQVARLRSDSAPTPSASTTVTSNPIPTVSTSPGGTERFPQTTPRRRGSAGTALTRFNNDSGRLPPSTPLAGCPVVPASNGITAAVVNLPVTQPTPSAALPSSFHAPIFARAAEMEARRRERMRQRLPLSRPLIPTALNHSLASSHTPSALVSNKPSADEIETPKSALTVDSPAMSDEEVDAEDEDEEDEDEEEFRVASTDAVERAEIGAGQHEDEFDPPDLLRADSSDHPMPTSVPSDELSLPSQPSMQSMLSTSQSSAFAGGSSHLQVAGQLVNRSRLSPVTESRFDEQRAARIAEPEDPILGKMGSPPEESFFDSGQPSSPQETVPSVMVSSASEKSVPSGQVLSPVPRPFMAGTGQGNIMIRSLTNDAHEPPELHRHSSKSSPTTQLTFAKRTIPPLAMKSALTAQLASQFMPSDNPFTDLYAAVSGRAEPSAVALALYFPHSRQNRDRPIQVTVRKDASVEEIIGFGLWTYWDKGLDPRLDEGLLPEGKSATGDKEREIHLSTVGWCLRMVEEDGEPDEDFPALDRSRPISKFAFDAYAICEATEDQVKQNEVDNAAIVRRPSRLTATRRQNTVGGLGIPESKPGTSVVTSSGITALANTAGLSGLVGPPVFLRVRMAAPDAPHFSTTIHTTSDTYIADVLDAVCRKRRLPNPKEWGLMTSDMTIAIPLDRTVASLEGKFNLVLVARVYLQENGFLAQRWKTTDPNASIYHKMADTADVKGSVETGYRKFNVYRKMPVLGRHERTLAIDGHYIHIFPSSNMRAFASSSKTSSHHITAVVSCKQSRKVPQTVKLVVMKDGVEKRYELEAENVKEAAEIVSSIKGLQKSYQLERNGTYARGTRARRSRVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU48</accession>
    <name>M5FU48_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626586.1">
        <property type="nucleotide sequence ID" value="XM_040768941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU48"/>
    <dbReference type="GeneID" id="63684003"/>
    <dbReference type="HOGENOM" id="CLU_1372176_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22683" checksum="23673FA49281F793" modified="2013-05-29" version="1">MPSDTVFPQLPYELWAEIISFCTSKRDLANLCSANSMIGFIASKHLYSHVRSSCVVKLAKLYRSVSRNLNIAAQIIALDVNLEPDHSENQAMIIHFKLQGARMRLFFRTRDLLPNLKSLDIQCIRGGSSEVWHALTKNLGYVRARLSRLTLPYARDCSALPVFRSQPDLEELYLQHRYGEHHAEELVNLPSTLLLVYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU55</accession>
    <name>M5FU55_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626596.1">
        <property type="nucleotide sequence ID" value="XM_040768945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU55"/>
    <dbReference type="GeneID" id="63684007"/>
    <dbReference type="HOGENOM" id="CLU_743989_0_0_1"/>
    <dbReference type="OrthoDB" id="3413943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42064" checksum="03D619E04E64D91C" modified="2013-05-29" version="1">MALQKIVALPYDIWKEIVGLVEDRGDLVRLCLVNSLIAPIAGKRLYSSPVLNDIVNTAMFYRTSIGNPTLAEHVTTMKLELDYIFWVGRNFLVGWQEVQAPAYLRLFFRLINQLVNLKELNLRSRESQGRTMSQALSVNLSRMRPRLSSFPFIGLFQCSARPVLRSQTSLESVHLAYCAGNDYAPELVNLSPDTVPQLRRFICDSHSTCQLVRGRPVEEFSLSDEGGYSYISPKDLSSCLAHLQLSLRPLRKLQIGIYALDSTTLVKIQGAMPHIIDLNIKTRAELEAQVRMSYLHLHATDGMQLHQIRSSSALDAFHRFSQLRAFKFTSLVFNNLHAIEISAAVDQIRLACPSLKTVVIRQPEEEDVIFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUK1</accession>
    <name>M5FUK1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tse2 ADP-ribosyltransferase toxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628328.1">
        <property type="nucleotide sequence ID" value="XM_040772861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUK1"/>
    <dbReference type="GeneID" id="63687923"/>
    <dbReference type="HOGENOM" id="CLU_113396_0_0_1"/>
    <dbReference type="OMA" id="AHERADH"/>
    <dbReference type="OrthoDB" id="10266325at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041018">
        <property type="entry name" value="ADPRTs_Tse2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18648">
        <property type="entry name" value="ADPRTs_Tse2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tse2 ADP-ribosyltransferase toxin" evidence="1">
        <location>
            <begin position="30"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15767" checksum="3C41FE6606F1AB72" modified="2013-05-29" version="1">MIGASFRPFARTIASRAPSRITRYDVFPDDMFRIQNGPQVRLREEETQQHRGRISYDIRVHKDGLVHPAVGDVYQGPNGCSDRPLCMYLLDLAQYFDETKTVAYRVPKGVQLPPRLVLLHEHTNHHALQCAVPMKLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUP0</accession>
    <name>M5FUP0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_55272</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626871.1">
        <property type="nucleotide sequence ID" value="XM_040775310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUP0"/>
    <dbReference type="STRING" id="1858805.M5FUP0"/>
    <dbReference type="GeneID" id="63690372"/>
    <dbReference type="HOGENOM" id="CLU_009063_0_0_1"/>
    <dbReference type="OMA" id="FMCHRSL"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="14">
        <location>
            <begin position="105"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="294"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="365"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="722"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="943"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT99973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1138" mass="131196" checksum="FA7E7049C7360149" modified="2013-05-29" version="1">MQAKRARTNGSQRNGHGSQRQNPRKRQQEVEEEMSEGEAEGDGDYEDIFPNGTDRRGKKNTRLTDEQLQQIKEDKEFEEEMEPKIQDAIFNRPKRQGDIAEMGIIQSLELINFMCHKNLKFHFGPQINFIIGHNGSGKSAILTALTVALGGKAMATSRASSLKTLIKEGEPAAEVTVVLKNKGPEAFNYDIYGDYISITRRLTMEGSTSYKIKGAKSDKTISSKRDELTAICDHMNIQVDNPMNVLTQDTARQFLSASKPKDKYAFFLRGTQLLQLSLEYELIRENNNRMGQVIGQKKEVIPELEKEADEARNRFQEAEKARDQRNRLDTLMEEKAWSIIFDKEKVSLMNRSAGISPDLVGFQEVKKHKERVEGAERVLPKLSTEFETADEVAPLEEKRTRVHGAVRNKKQEIMQITNDEKEMNGEKKRIDQVILELKQQLEEETRKLREDTREQHEAAQARLHVVREKLEEARTVVAEHARHHDELRNQHRKTKEELKEAEREREDVKKAIQESQNVITHMQKTKTNSMQGYGNKIPELLELIKQESNWFGQPPLGPFGMYVDAKQNAGQFVPVLKVILGHMMRGFVLTDARDRTKLKRLLDETNNRDTQIVISERDIFEYAHAEPPPEILTFLRVLDFKDEWVKRIFINSHRIETTLLCKNRAEAASLFNQYSMIGSAFCADGLQYRKYKYECSFSTRTSADTSPIAMEFLSSDDINPSASDAKEKLHSDERRYQEIVQQLQPLQRNLTQFEAELKRMQRTGEELERAVRVAQNEVESVELDMRQDEPANLDSIQQAIRETELERQNIISQFTTLEERRTEIDNEVKPLLAEQESLKEQMAKYEIRIADLQTHLGDLAAKRAQAQSNRNHYEIRLQEENKKITDLRGVLQASEQELTNWTAQVTEKYNRIEKARKTETIEKEIHGIERALKERAARGGASVDEMAIELTRTKATLDQAKKDLSDMEKLQKSLRQALYARQDKWHTFRRHIAIRAKLGFQKYLNKRGYFGKLDFNHAVNTLELKVQTEDAVGTQRAREKDPKSLSGGEKSFSTICLLLSLWEAISCPIRCLDEFDVFMDAVNRRISMSMLTSTAKEMAGVQYVLITPQDMSSIKLGPEVRVHRMNDPERGQGQLNFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUR2</accession>
    <name>M5FUR2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PH domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_101377</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626127.1">
        <property type="nucleotide sequence ID" value="XM_040767550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUR2"/>
    <dbReference type="STRING" id="1858805.M5FUR2"/>
    <dbReference type="GeneID" id="63682612"/>
    <dbReference type="HOGENOM" id="CLU_537493_0_0_1"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="178"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="55845" checksum="CA0797BB1F356885" modified="2013-05-29" version="1">MPHPLEPTVLNALNLKVLRRHCPQIKDIYDQASYVVLYRSILKHPEDPESKEREWSKKDVHVEGSMFLVEYETSPPHGFYILNREGLSDFKHVFRAGDKFEYKSDFVIFQGEGSAEIWGLWIFEEDQRKRLAKKFLYYHQLEVDPSTAAPSDPPILLPNGKPQPQTVDELFQNLLTLPPAGSTTVSSPGTVTSSISTTPIPTAPVLATGPPTRALGRRRGESVSTPSQEPQKQILTASTGPGGVRERGRDRERERTDREGREREGKGKKQRRPKSVPPQQADEPSVHAHGVPPHMHMPQQWPAQEMNGQAVVQDPSVSLKQIFGLLPGPAPAAPTPPQSSLLSQTQPPAQAQAQTQGQGQGQGSTACPGGGWPPLPGGVDKIKEGREGKGHGRKKSALQSQIQIQIQPQPQSQLGLAQAQTPTATQYIPQPGLNGESLVDPESVKEAIVEKMLLLKVNGEAEPGAAGKACSSQREFVQEVLRLIHTEREWTRELWEAYERRVGGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUU2</accession>
    <name>M5FUU2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_52736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775127.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="10409" checksum="04D0CBA6DF0E5941" modified="2013-05-29" version="1">MRKETQAGLEHDKTLDICMDMNAPIILIPKHIMAKQCAHMILDAGHIAIQSGLIEKSTLAEIDMKHSQQYSEENYKQLQSHMYNHFFLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUZ6</accession>
    <name>M5FUZ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_119591</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624009.1">
        <property type="nucleotide sequence ID" value="XM_040770828.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FUZ6"/>
    <dbReference type="GeneID" id="63685890"/>
    <dbReference type="HOGENOM" id="CLU_001592_2_1_1"/>
    <dbReference type="OMA" id="KAVFFCA"/>
    <dbReference type="OrthoDB" id="5330228at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="520"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="1398"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="623"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="981"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1647"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1704"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1345"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1000"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1019"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1734" mass="194382" checksum="198BAB6565897C5C" modified="2013-05-29" version="1">MGANLVHVHEPSLQSPHEQTTTSLGSLQFSDILASSSTSSLRIREYPHRQREMVVPLIWQESTHTIDVRPLDREACIEQSRAVRRFLDIPLLTKFIDGSYKDISEEKADKRNRFVKLMGKGNGARGTKRQREGGGDSRSSRKKAKRNSGKAAPPVAVVNDIEDIIITESVPDISMDDNTPDPVTNEHQHTSNDAVHAVAAEPAPTKPMFTLLLQVNLKLVCGTEAANFSPSSKLHKLCSLNTLHKDEEGLIALIQRLLHHTPSSSGPIELGHVNLRPWGTNLHVHGRINDKRETLPMFTFKPPVPFGGEAEDWDFPIPVYSSSSSILHAALHLCGLPEPRVRIHAILLADNAVITTWRGKQAPLGVQFYLSVSLDILPSMLSDPGSLPLPAQEAQRLLLSHVFSPPPGPPNYPGSTNIHWFYELLGPAPDLPEGEEARYQPEKLDANLLPFQRRSVAWLLQREGVLLPPTSHGSSIPPVEDACFLYQRALSPFVPAEKELWFSPLMGSLLPSPPSDLAIRAGADGIIGGMLSEEMGLGKTLECLALILLSPPPVSRGPETVRAQMVYDLSGEARETRVREVGTTLIVSPASLQQQWADEIALHAPELKVLVYKGWKKEIEGVGKERRSGGRTKGTKDEEEKENDDDTFLSTWATATHKYDIVLTTYDDIRKEFYVSQPRKPRPKRDTAVYTHPEGADAVIRSPLVSVEWWRVVMDEVQQQGDGKAASVVSLIPRRSSVAISGTPVDDEIRDLFQVLKFLRVPILSDSPRLWTRLLKPAFAPHFQELFQRIGIRTLKKKVADELTIPPQRRYLVPVELGPVERHLYNDLLDSAYSALGVDSLGNALGGSGELEVSQLRTWLLRLRQSCTHPQIGQMHRNDRVLGGALRTIGEVLELMRYQNRQIILNEKRDRLAHRVRLALMLQLDESNAARWKQSLELFLALKSDVQSLVDEVKGILDVQIFAARAERKAAREKANGLSDSYLLEDGSRPAKRKGKDVEPDGYETDDDDEWAHDEETAEESKGRGVHKENRVKTSHVRIRECFVLQHKIFFSLGDLYHKVAKQEEDAAYADAETVRRAVLKNTEDLALRAMYKLTHEVAEKGVNERELEVELCGKPGLRAGLLFDEANDIIELLNDQRELLWKWRGMIYTRLTQKLTTAEGEEASGEEYTHALDAQGEAEAYIVVYAALLADRKEALSQERTILAVHESREKKARDTRAALNAGLENTLSGAPAAMEPQNEVLMRQLTDERRSMRDAHSKRSLKNVFPEMSGLADRHDKEMEGVILRSEAMRLRRIVTDQDVLCSRLESELAIFRQAFNGRIVYFRQLQELSDSVMDFDVKELGVQSLAEAIREAEEKVHKFDDTLRTLQAKQRYLEYMDEGQTNEALGMDNTETRECVLCACGFENGCLTACGHIYCEDCLNAWLKKRGTKFCPVCRQPLSKQTIHRIVFHAGEKVDEGEELVEPEGAHIDYNVMDLELLREIDDIEAHGNYGSKVQALVKHLLYLKKKEPEAKSIVFSAWMDSLNIIARALQENDISCIRVEAGRNAAREFRLDPVCRVLLLHGERENAGLNVTCANRVFLLEPVVNHAFEVQAIGRVDRMGQTRNTEVYCYYAIDTVEKGVLDLAARKGVSIYTKGHARGTLNMSELGDEGLRNSPRKGPKGKGDFMAKTDDMMAIVFPHLAEVPHDGSVIEVDIDAEEEMQREIQRRQAAAAAERRKAMQAGPSSRQEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV35</accession>
    <name>M5FV35_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_101499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626347.1">
        <property type="nucleotide sequence ID" value="XM_040767561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV35"/>
    <dbReference type="STRING" id="1858805.M5FV35"/>
    <dbReference type="GeneID" id="63682623"/>
    <dbReference type="HOGENOM" id="CLU_074878_0_1_1"/>
    <dbReference type="OMA" id="SPFFMNA"/>
    <dbReference type="OrthoDB" id="5553476at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="9">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="225" mass="24439" checksum="86C265A0F4B7DF83" modified="2013-05-29" version="1">MSSKPPNPASSASFDEVKRSLLSQSFKSGALKFGSFVLKSGRVSPYFFNAGLLSTGSSLSPLAQAYAHTLRSLPQFDVIFGPAYKGIPFSALATYALFEQGVDVEYAYNRKEVKDHGEGGSTVGAPLKRKRVVVLDDVMTSGLAVRESLALIRQEGGEVVGVVVLLDREEVGREGKSSVEELRGEGVEVRAVLGMGDLVRWLEEKGMGDEVERMGEYREQYGVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVC9</accession>
    <name>M5FVC9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_23666</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626467.1">
        <property type="nucleotide sequence ID" value="XM_040773334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVC9"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="552" mass="62580" checksum="B3119D6D6A6A4EB4" modified="2013-05-29" version="1">MSISLFLFVLSVLLVFLGWRLNLSRFRLPSYLRGPPPESWLLGNQGQVVKFEAGVANRKWREQYGYVYRFHGCFGIEYLMLNDANAIQHVLRGQTTSWGLDDSLRQFLRLVTGEGIVYADGADHARQRRLLSPAFNPVFIKSLAPTFASCASRLVKEWNRRLDAEGIDGNWDVNAYHWLELLTMESIGATLFGLRFGALEGEEHELMKAYSGLMADTFSQPTTVGILLQNIILHIPPWIIHHAENLPLSAMRQLRAAKTTCHQFAHDLIAQKRKEIKADPTKKDRDLLTILVKAGEKNEKEAIEPMSDELIYNQLTTLFFAGYETATNTVSFALCELAQRPAIQERLYAEVSSVLGTAADDELAEGFDANNLDNMPYLEAVMNETLRMHPAANHTMRAATIDNSIPLSKPIDAEDGQHVHWIPVHAGQRVILNFDGFNRSEIVWGTDANVFRPERWLENVMSKVAPEDQCGGPYVNLANFGGGPKACIAWRFAIIEMEIFIAMIIRQFEVRISNPDYEMWRECAFINTIPMQKGRLDRGSQVPLRIQRRMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVR9</accession>
    <name>M5FVR9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627346.1">
        <property type="nucleotide sequence ID" value="XM_040768828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVR9"/>
    <dbReference type="GeneID" id="63683890"/>
    <dbReference type="HOGENOM" id="CLU_1555208_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="19482" checksum="9F12666BBB4A4764" modified="2013-05-29" version="1">MGHLISRVLVKQISEKLTEEVLRVPLSNACSHILFGRYWSDIQSISKLHIPSMELLAAITEGVWLAMRIFSVLGMSVIFSLVGGCVLMCLCDLKLAAVASVIMSAHRQAVNEREQGLHSRRCMRFPIYYFFTRFKYWMPTAVPHFAKFAPSWLQLQKESVPLRQTGPGADIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY0</accession>
    <name>M5FVY0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_89572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627416.1">
        <property type="nucleotide sequence ID" value="XM_040776919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY0"/>
    <dbReference type="GeneID" id="63691981"/>
    <dbReference type="HOGENOM" id="CLU_2209928_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="107" mass="11753" checksum="581C6BE00ECCE976" modified="2013-05-29" version="1">MWSKAWGAWHSAPRPPLPQLPPTSSLICSSFLLPLSSLVSFRGPGTFPLFCLLQLTPTPPLSCLLQLPPTPILTVTAELSPLRFRSPNRPVPCLPFPLKCPTAWKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWB5</accession>
    <name>M5FWB5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626877.1">
        <property type="nucleotide sequence ID" value="XM_040773274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWB5"/>
    <dbReference type="GeneID" id="63688336"/>
    <dbReference type="HOGENOM" id="CLU_903214_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="308" mass="33578" checksum="A2945614DDE88C0E" modified="2013-05-29" version="1">MFYTNDDDCSRSYRQHPVLALVFNSLYAPPRGEKVAEVADPVRMQDAAPGAYWAEVPRGPPPIQYPAYPFPGYWVGYPGGITPYTPFTPQRGSQPLAWPADPPVGVQGNQPYPFMPWMQPGPQMFPATPPNGYDQMQYGRSSALGNNVQEAPIPTGLVQSATGLIIPIYSEVVFNRYLAENPHVIDTRRFFPNPMAQAQAGMIMPHTPQSILPNRGVFDSNGGGQGNLFLHHERADTNQSFTSTNSFSTAASDGSPSRMPCGPPPAYGVHPLMGHAHGYPVAPPHFIPQRLGPQGGLPEYQPFHEAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWI3</accession>
    <name>M5FWI3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_116022</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629193.1">
        <property type="nucleotide sequence ID" value="XM_040770118.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FWI3"/>
    <dbReference type="GeneID" id="63685180"/>
    <dbReference type="HOGENOM" id="CLU_000777_0_0_1"/>
    <dbReference type="OMA" id="VAFCEYW"/>
    <dbReference type="OrthoDB" id="10255632at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="1952"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="956"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1209"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="956"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="2139" mass="235848" checksum="0D821BF14A375FFC" modified="2013-05-29" version="1">MPPAKTTRSANTTQATSTRNRTTSGKTVKSTNANSQGSDDVDALAGRMTGTLRLNATSSVGRKPTRTTSTTVRTENPHSKSTAENVPVTPKLELSPTERGKHAMRTVNSTMQSLVEAIQKGWKAPHAQSKPTAPIRSRALNKQEDSGEGVCTLESITSTAAKCRSALSSMRGLKDQVDIKPVDIERAAVNVAGKLLGLEMWTLVLEFLTDSRPSVLDLYEHLPLSARITKTSTPAVGKSRTGQRVPSSRSVVKESTSFGQHCELLLFPTPSDPDNIDVAALNVIASSQLYALTSLVHLVNPASIRELSQTLAAPGNMLDFVPVLQTRLGSKFYSSLALSTFRAIATRLSSSEAHSPDVLFSVRLWALRCFIQADGINGNDFWDQTMRWAASYLKTIPSGSKDQEKAASAQIMTVFSELVDRAGARPDGRDFANGASFGKMCDWWISLARRSGNLEILTTVNNILASTSTTATSIKSSSNLDTRVAANESQGMDDAGMLLSKIYARVSHVEALVSKLAKDGDDKGVEDHLDAILSDIRHLRRLYTSGVDGVHRLQRETERLRHSCAKLLEKTLEASLSGGRLRPACIAVLESLIDVAESTSTPADGDSVPNKPSAEFQKDMMSGALDSLLTLARVVLSPTQHLTYSLALGYLERAHKLTTSIPSGETVQYLRCLGAAHQNAAAVLYKHNKAEFAIRFAEQAYLISVQMFEASDGANNEGSALREQLGRRAEILASCYLKQGDRKLAYRSYCDALSWISFNTISALQSTLAKESVFASFAAQPTVSALIERVTRLAVSDLLLPPKEASLRHQLEGRAVPTEVIGGLLEYQILTMDNMLHKPECLPAISNILDELLNLYAPDIFPIRRSRVLLRNLEHLYHIGSNSSALIASDILEGFVGENKANDAGLAGYIPLYQAFTHVWLAIQSHGNADSPSMPAVVQHTDEAVRIFRQVFIPGSVPKPRSASPKSRSLGKGPSKPRPAQTPKTPARGRRAVSTKTPKVTTSLTLSNDRATITSAALDNVERLYKHLELLSDLLKFLVLSFQRIDLLEIMRHFNQHRIERSLSCDEMLRTTTELAYENARLGKTGRASHLYAQAMNCALHDDCTTPLSDSARILYLLRYASSLVIHGNLEKSSSLYQEALETAAAMETDGPNTTVGRIRTRTLVLEQAAIASSVYALIKDEQDDMPSCLNALEQSLRLWNRAMDNVMRLNPSHSPPPPSDLDNPFVDDDTTTKPKQSAAKIDTRKCVALDGLQWRVAAGMFQALLFLAEYHCRAGAPRAALLYFGKAVEMADGLAAPLPHGTALALQEELKLMCEDPVGEGFSRSDELLGQLPTAGLIEMRRIQGDQCVKEENKDLGRQIYASADTILKDLEKTYTLAMTTQKTPLKISRKRVEKPVADGELDVLLPTLQAALLRQQVWLFKEPSEAPEFEELLTRLLSLPPTRNLKAEENSLLGRVHMHDACNQFRNDLFLSSLTESIIAVPMGMISQQCLTPSASSIQVLDTLHKAEQYFADALELMLCKGRISETRSVSVNLALIHAFQTMLGKTSSNGPRLAASLLEMCAGTSLHRQMLESTDLKLQPSKHSDDLTWPSTAPKHVPAKQNQVLLGSTISDEDICSADDDDEEDLDRSYWQATRDRYIALLSDVGLQGPAQVDVLPSNWTVISINVTEDQNTILIARHRSRQEPLILCLPLDRQGKRDGEDDQFTFQSAIDELDNIIENSNKGILAAKEVAGKDATASWWSERGELDRRLGELLETIEFCWLGAFKTVLCEPPRATKESLKSLRNRLEKIFQGAIKALDKNSPASRTRLHDNILDCFASLSTKCRDEELEDMIYFVLDLYHFHGIPVAVAEIDVDMLVVDIRSALEEFAANPPVLCSSQADPHLFLILDKNVQGIPWESIPILRGRSVSRIPSISFLVDRIELSRHRRGPETEPTASPRKIDRVVVDPRRAFYMLNVSRDLTRTEQQFSPWLKEMDQIGWRGIIGRPPMAGEMLRALESSELVLYFGHGGGEQYVRSQQIRRLSRCASVMLWGCSSGALRSMGEFDRFGTPHNYMLAGCPNVVATLWDVTDRDIDRFSDSVFKKMHLDRAHVETWSASQPSMTSIVAAVAQSRDVCKLKYLNGAAPVVYGIPYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWS1</accession>
    <name>M5FWS1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_18418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624789.1">
        <property type="nucleotide sequence ID" value="XM_040771358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWS1"/>
    <dbReference type="GeneID" id="63686420"/>
    <dbReference type="HOGENOM" id="CLU_362910_0_0_1"/>
    <dbReference type="OrthoDB" id="3423247at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="770" mass="85226" checksum="061B9E2EF049A32E" modified="2013-05-29" version="1">MPPLVMTDKDAWDEVETQLALHPEDGEEAEVGMRLEGWLDAMEEVQHSSMEAGACLDQPLHKDKYKPTDEMQLQPQLHQDPQLEPQQLPPELHMSYFEPPQQLPMSKGGGDGTTCLLTATVSAPTKETDTGLLLQTEGRLLSSRGWTTSRTATPAPQYEINEVDLDEMQFGEAHELDGMEQEEEVPNKEIEINEIEKDEIPHTSLPTTVSPMTASAVDSIWETIWQSAAAPPQGTKVPAICIQSHPPLPALDDLHECLLAVKQRLAQEGAEFVVHKTTEPGCPSLQEVEDLSLFTSTVTKLSNFLKHHYSTTPTRLADALLHDICAAAATHFSKSFNAWNDWQACCTEQHPDWDGPWVKSEWAHLKEHCLPMSALWPQLCNVLHSHAVLVSGQNKDLSVPDNAGRAAAAHHMQFNNYAHAEQLEISQMEQFGIDKVIFLVSQNLQDGPQYACFILSTGAATFFDIDTWPGRWQKAVDLQSYMKTLTLVKESYYQTISLSSLPDNLPIYFELPPGYIPWAASVEHTQVQPGSRQELLMLQPLSLLQPTIMLQPTSTLQPTAMGHLPLPALEPSNPEPEALSRNAVFPVSSMPPSSSLTVFLPPSLPPLRLLGEWTKLGVRERERRYFDFGVRRMRGLMCPNRRRRDRGGCPFLASAWTSVCSAQKSQQPPVQMGSNATGAPCPCMAYGTVGHPFPRLALSTTDWGLTYSIPLPSPKEPSDDLSGGCCNGLLACEGSRSGGRAITRLPLVERAEDELEGWQHKTHSDGSQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX00</accession>
    <name>M5FX00_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_117278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MCM10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627117.1">
        <property type="nucleotide sequence ID" value="XM_040770351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX00"/>
    <dbReference type="STRING" id="1858805.M5FX00"/>
    <dbReference type="GeneID" id="63685413"/>
    <dbReference type="HOGENOM" id="CLU_015393_1_0_1"/>
    <dbReference type="OMA" id="HEDFQDY"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="3">
        <location>
            <begin position="402"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="736" mass="80552" checksum="242885E3070B28B4" modified="2013-05-29" version="1">MNSLRQTATTHEEQQALLRAQIAALQAQLDPSIAFRTPEDVAREKEKKGKRVLVGDSPVKDASKRRKIEQPQVVHKGPPFPQPVNTPALQSSTPTQHPSTSSRPPRPSNMLSSLQRLHATPEPRAPEPVQRSSAFHAPAVQVVPVVGRDEELKIIEQLDPGPRECKPSAEDPRFERLEPNSGIRLSSRRVSHEDVRSYLTGRFYLPPSLLYSVVRLSSDKQGYDVPVSGDWVTIAVVAERGEVKLSRGAVRKDGEVASSDEEGGKKKDWRARERKKLEEEEKGKGKKYITLKLVDFGNKPAGGGTGSTKGGSSRGDAMLCLLLFEANQVREEPDEEGGNKVYKGGSGGAFELWAATLREGSVVALLNPRILRPFQGGDNRPHRTDNILALTPSTEESVVVLGQSLDLARCAARRKDGSQCNGWCDRRANDVCEYHIQQRVKTLRAARPEFAVGTSGFTTSRPSSGPDYQKKQGLLPAKGRPMTAPRDSGGGPTYIMEGHVLRSNARPAPQEEFVGEKLGRERVERDLRKKKRSKMDEELKDLLDGKTTKLTIHGNRIGRVVEESTEHAKVKSAFGPDTVKKIGFNPAFMGRGGQAEADKRKAEAKNRDVHALLDRRDVHIQPKLGSRPGVKVRSGVSVPAHLADPPAPSVEDAQHSLSDLELLEGEKNDPARMVDADSSDLEIEDTGTMTTIPAIKRKTNPAEDHLGLVDGGDLCDLEIEDGGTVTTMATVERESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX16</accession>
    <name>M5FX16_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_22809</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627866.1">
        <property type="nucleotide sequence ID" value="XM_040772959.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FX16"/>
    <dbReference type="GeneID" id="63688021"/>
    <dbReference type="HOGENOM" id="CLU_000844_0_1_1"/>
    <dbReference type="OMA" id="AWTDFFI"/>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051278">
        <property type="term" value="P:fungal-type cell wall polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056261">
        <property type="entry name" value="FKS1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23605">
        <property type="entry name" value="FKS1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="605"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1247"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1297"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1388"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1414"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1503"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1546"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1582"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1686"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1739"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="12">
        <location>
            <begin position="248"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1777" mass="202476" checksum="917E6D4E36BB8C72" modified="2013-05-29" version="1">MSRPPAPNSYNAPYAPPPDPRDPFSTPSGQPQGQRYYDDDASQNGAYYDQSAPYDSYAQPRDGDSVSEADVYGQRYTPSAESLMPPRMATSESSTQTFTDYVPQGAREPYPAWSPGRQIPLSKEEIEDIFLDLTQKFGFQRDSMRNMFDFLMTQLDSRASRMSPNQALLTLHADYIGGQHANYRKWYFAAQLDLDDAVGSSQNPSTLTRMRSMRGGGPTRSQPKTASEKSLHTALNRWREAMNAMSQYDRLRQLALFLLCWGEAAHVRFVAECLCFIFKCADDYYRSPECQNRVEPVPEGLYLRAVVKPLYRFFRDQGYEVVEGKFVRKEKDHEHIIGYDDVNQLFWYPEGIARIVLTDKTRLVDLPPAKRFMKFDKIDWNRVFFKTFYEKRSFLQLLVDFNRIWVIHISLFWYYTAYNAPTIYAQPGTTTPTAPMTWSCTALGGAVSTIIMILATLAEFSFIPTTWNNTSHLTRRLLFLLVTLGITAGPTVYIAGFDRTSQVALILGIVQFCASVSATVLFAIMPSGRMFGDRVAGKNRKYLASQTFTASYPKLDVKARTASLGLWVLVFGCKATESYFFLTQSFREPVLVLVGMRVQRCSEKYFGAALCSNQAAFTLTIMFLMDLTLFFLDTFLWYVIWYTVFSIGRSFALGLSIWTPWKDIYMRLPKRIYAKLLATADMEVKYKPKVLVSQIWNAVIISMYREHLLSIDHVQKLLYHQVQSDQDGRRTLRAPPFFISQGDRTYKGEFFPPGSEAERRISFFAQSLTTAIPEPLPVDAMPTFTVLTPHYSEKILLSLREIIREEDQNTRVTLLEYLKQLHPIEWDNFVKDTKILAEEAAAFNGTASNPFGVNGDEKSITNKADDLPFYCIGFKSAAPEFTLRTRIWASLRAQTLYRTVSGFMNYSKAIKLLYRVENPEVVQLFGGNTDKLERELERMARRKFKMVVSMQRYNKFTAEELANAEFLLRAYPDLQIAYLDEESPGKEGGEPRLFSALIDGYSEIIPETGKRRPKFRVELPGNPILGDGKSDNQNHAIIFYRGEYLQLIDANQDNYLEECLKIRNVLGEFEEYSLSSQSPYAHWGSKEFIKPPVAIVGAREYIFSENIGILGDVAAGKEQTFGTLAARALSWIGGKLHYGHPDFLNAIFMNTRGGVSKAQKGLHLNEDIYAGMNAFGRGGRIKHTEYYQCGKGRDLGFGTILNFQTKIGTGMGEQMLSREYYYLGTQLPIDRFLTFYYGHPGFHINNILVIASVQMFMVALVFLGTLNKQLTVCQTNANGDVLGGQPGCYNLIPTFLWIQHCIISIFLVFFIAFFPLFLQELTERGTGRALLRLGKHFLSLSPLFEVFSTQIYCHSILSNLTFGGARYIATGRGFATTRISFSILYSRFAGPSIYLGARALLMLLYATLSIWMPHLIYFWLSILALCIAPFLFNPHQFSFADFVIDYREYLRWMSRGNSKQHTNSWIGYCRLSRTMITGYKKKRLGQRSEPLTGGDVPRASWRAVLFSEIIFPWIMAVLFIIAYMFVKSFPDPKTGLSANPIVRIAIVSLGPIVWNMAVLIVLFLVSLFLGPVLGGACVKFGAVMAATAHFLALFGMIGFFEFLWFLESWDVSHAVLGLLAVIFIERAIHKTLISVFISREFKNDETNRAWWTGKWYGRGLGHHIMSQPAREFIVKIVELSLWSGDFLLGHVLLFMCSVPMVIPFVDRLHSTMLFWLRPSKQIRAPLYSLKQKKSRRYIVIKYTIVYILVLATFVALIAIPAIFRNMLNVKCSFCESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXL4</accession>
    <name>M5FXL4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629655.1">
        <property type="nucleotide sequence ID" value="XM_040768344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXL4"/>
    <dbReference type="GeneID" id="63683406"/>
    <dbReference type="HOGENOM" id="CLU_1875367_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="136" mass="15816" checksum="7EE93A39046713F5" modified="2013-05-29" version="1">MERRLLEYPDGYLHIAIRGLHLPLRSKPVAFDPPCELIFMIAAATYLIFIDVGEDETEYTWFLRYSELGLTDFLKAFRVGQIQMERSLCYCCMLDRDALGHDEAWFDDWDVAWQGLQGGGNWIPYAVVDCLKRLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXM5</accession>
    <name>M5FXM5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629670.1">
        <property type="nucleotide sequence ID" value="XM_040772528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXM5"/>
    <dbReference type="GeneID" id="63687590"/>
    <dbReference type="HOGENOM" id="CLU_606935_0_0_1"/>
    <dbReference type="OrthoDB" id="10395768at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="50360" checksum="51D242054E620AD1" modified="2013-05-29" version="1">MSDHNTPPVAVITRPDGESFTIIDQHYEQLRADRESLNLYRSRAANYREAADKLLEAARLLEEECRPIEDRLSKTRQFCQASLSDSPPSDRASSVLSTVQQLASEALPVVQQLPAYNQGLTNGNGAVYPRHMGLQYVNAPATPPSPHREHQPYVLPERHHTHTPVSAQSYATPNGQRPLKRSRSMVEEDELEEDRKSSPRSLTSTDGMVMKMMPHEQNAAPARKQGKFTDDDRHKIAAYLATTTSRAQNGGIDWKQFALSNPKYDATGWRTQYHSRKHKIDPLIEHYRPQQAAHGQSQFQQPAQQPYVTGHGAHTPSVTAQPSPPSAYAQPAPAYAQPEQYAKIEEVRPMAPSVYAAPELEREEPRGSYAPSASVYAHAAIISYASHSPAATPEPQQPRLSDARDEPMEDRDRDRPREHQHQHEYDVERDQDHADGPPAPPIATVSVAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXQ3</accession>
    <name>M5FXQ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629705.1">
        <property type="nucleotide sequence ID" value="XM_040772543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXQ3"/>
    <dbReference type="GeneID" id="63687605"/>
    <dbReference type="HOGENOM" id="CLU_2687785_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="74" mass="7809" checksum="7261CFC3D3CEF68A" modified="2013-05-29" version="1">MHRQDKHGLNPLTPSAAPPYMLLAASSAPASHASASILVRKVAIKRPSKPMTPLRTPLLELDPPAEPVVLVPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY07</accession>
    <name>M5FY07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NOT2/NOT3/NOT5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_94109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629835.1">
        <property type="nucleotide sequence ID" value="XM_040777200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY07"/>
    <dbReference type="STRING" id="1858805.M5FY07"/>
    <dbReference type="GeneID" id="63692262"/>
    <dbReference type="HOGENOM" id="CLU_033275_4_1_1"/>
    <dbReference type="OMA" id="IFYMKPR"/>
    <dbReference type="OrthoDB" id="25391at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="192" mass="21427" checksum="11821899C081526B" modified="2013-05-29" version="1">MIRSSATQPDIALLSVGGVDLTTSLNLAVGSKDDLYPTFYSPYSAPGTPPQTVEPDFTLPSCYNVQAPMPGPQKAAAFSDETLFFMFYSSPRDILQEVAAQELYNRHWRFHKDLGMWVTKEPEYNDPSQTGPGTETSETNKRLNGAGEKAVYTYWDVEKWDKERKEDVVMFDALEERQPGMALPTAATGARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY77</accession>
    <name>M5FY77_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_108818</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627657.1">
        <property type="nucleotide sequence ID" value="XM_040768744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY77"/>
    <dbReference type="STRING" id="1858805.M5FY77"/>
    <dbReference type="GeneID" id="63683806"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="ANVWHIN"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU00760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="472" mass="53133" checksum="7505BB00A5C9252E" modified="2013-05-29" version="1">MYVPLSLGSLVLLGIAFAIRAIAAIRTQPSPQLPPGPKGLPLIGNLLQVPSRLVFLKFVEWSKEYGPLASYTVLGQPVVLISSAKAAGDILDRLSSKTSDRPRLIKLAYLTHSMEFAFANRGSFWRTQRRAAHESLNIRAAQKFQPIQEEESRIMVEDLLRHPDIDIAKHIYRHSSSIAWRVLYGHEAIDLRDDKAQVPSENFFEPLFSSAIPGGSIVDIFPFLQPLISRSRFLRRHSEAWYEKANTFFINAHTRPQVPVHLKHIFEVVYGGHASISANSHCGQSPDNDHRGARIPAFEDLEHLPQVEAIVKEILRWRPPTPTGVAHVAEEDIIYNNYLIPKGAVIIPNTWSICRDPSLYRDGDAFDPSRFLDEKGCIRKPPPDSHDDYLVFGHGRRICIGKSLAMNTLLIAVAQLLWAFDFHGVKGEQGNEIVPDPSAFWDNGVTVWPKPHQVRLVPRFPDLFERLKSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYD5</accession>
    <name>M5FYD5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795885">
        <property type="protein sequence ID" value="EJT96537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623435.1">
        <property type="nucleotide sequence ID" value="XM_040774255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYD5"/>
    <dbReference type="GeneID" id="63689317"/>
    <dbReference type="HOGENOM" id="CLU_129407_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="188" mass="20956" checksum="191B851271866767" modified="2013-05-29" version="1" fragment="single">MANPSATQNVSINIGHSFPVPQVFLPQINHALTQLETELGMASINVERAKLSVSQAVDHLNYVRAHYPTFAAPFYYLREREAQDGVNRAYEHLVQARAVERGVERRIRALRGGPSMSHGSYGYGYGYAANHPGPNYPPPPPTWPPSHSTYPPPSQHDNSQNALGGNTIHIEQHQNANDFDCMAEMKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYE1</accession>
    <name>M5FYE1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSF1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627757.1">
        <property type="nucleotide sequence ID" value="XM_040772932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYE1"/>
    <dbReference type="STRING" id="1858805.M5FYE1"/>
    <dbReference type="GeneID" id="63687994"/>
    <dbReference type="HOGENOM" id="CLU_067902_1_1_1"/>
    <dbReference type="OMA" id="YCPWNEK"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="183" mass="21093" checksum="FABFD74BAFDC1851" modified="2013-05-29" version="1">MVQYFSTAFHYDHPWSRVQVGMWQKYPNPQCAHVVSVDVIDRSVHPETGVIRTERLVGCKQAAPGWAIRFLGGTEDAYVREVSFVDPRTKKTWIHSTNLSLCEYMTVVEKITYVPSTSFPHTRTHFHQTAEIQARTKLWKTVGQKIEQMSLDRFKQNAIRGKEGFEGVLRTLFGEDNMQDISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYL0</accession>
    <name>M5FYL0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">6-phosphogluconate dehydrogenase C-terminal domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_52969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628501.1">
        <property type="nucleotide sequence ID" value="XM_040775140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYL0"/>
    <dbReference type="STRING" id="1858805.M5FYL0"/>
    <dbReference type="GeneID" id="63690202"/>
    <dbReference type="HOGENOM" id="CLU_031468_2_1_1"/>
    <dbReference type="OMA" id="WTRTTIG"/>
    <dbReference type="OrthoDB" id="3609at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF43">
        <property type="entry name" value="KETOPANTOATE REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="3">
        <location>
            <begin position="208"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="37001" checksum="1F55335A8D11F0CA" modified="2013-05-29" version="1">MSSSPQLLDVLLVGYGAVGVMYTYFLENSGRARVTAVARGNYALVKERGINIESGRLGNHPGWKPFRTFNSVAEAVDRRYHYVVVTTKALPDVLPTSMLLAPLLSLEYMFPQPTYVLAQNGLGVEEDLYAASKARFAQEPVIITGAVFLDASLTDSRDGLVQGTMEKLLAGLYRGDESPAPTPEMTASLQAYVDIMKAGGSNASVAENIQCEKFMKNRWNAVVASLCTLARSPPPAMSVTPRLEEIVEGPLHATLQELTALGQALGYPITGEDAQFLTNRTLRGFSKTSPHLPSMLVDVQRGSPLEVEVIIGTLVRWGKKHDVAMPRPVQLKPTHDFAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYU1</accession>
    <name>M5FYU1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_110626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625624.1">
        <property type="nucleotide sequence ID" value="XM_040769092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYU1"/>
    <dbReference type="STRING" id="1858805.M5FYU1"/>
    <dbReference type="GeneID" id="63684154"/>
    <dbReference type="HOGENOM" id="CLU_012597_0_0_1"/>
    <dbReference type="OrthoDB" id="2534600at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="724" mass="78190" checksum="70A82C98774D954E" modified="2013-05-29" version="1">MSCTHVIQAATQERKRQKAAQHTKSRTAAASPTPGQGTPQQSPSRRTSFNGTTIAIGSPAPTHQSLESGSSGMVEAIGSRQSSPGSTSTTSTVQLIAWLLAPDGEASTPHSQGLSGWRGRQGQSMPASESITGELSPVDQLLVEDYMRNEFALDLTETYFQIVHIRIPLLNPDLFRARLRASVPSTSLPIPPGYSSIAEALGPPSPALLATLMACGAKFSDHHLMQLDRETNGGSSRIQSRLLERAVEIAEAEKVFRTATLENVTLSMILEGMDPLTLGRPDRPDGPGGFWLKVAADHIFALGYNKDSVVSAIPDVETKGRAYFAWWITYLTDAYSAAFFRRKPALSDHDHSHAPPVAIDTTQYSDHSEFAIWLSAVYDLAVAARKLAVTAFSARSQTRGIVATELREVAALLYRWRDNHLARVGVPTTMQVDWDYLKAITCCVSDANYHVMWIIGHLAILDFDISPGGSNVAQPNTPPVDTDSTRLVQDLKAEFAYEALHAATRISALTSLLTSHGYLRLDYNVLHYAIYAAGLTLAREGAPETVNCIAGLRQYSSAYPDAGPEADHISTIFAQTTMTQHQTSARHATGLQFMPLNTTTVSSLPPLRSAESTAIDLNDPVMSGPSLGLNSEIGANHQSSSLPSAPFLDFGPNVSLLQPPDLASAVAEPFLRLGLSVAPSTQTQRGQASINDASTTTQRLQDEIMEGDVPEHLTNDAFDHLLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYZ2</accession>
    <name>M5FYZ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630160.1">
        <property type="nucleotide sequence ID" value="XM_040777603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYZ2"/>
    <dbReference type="GeneID" id="63692665"/>
    <dbReference type="HOGENOM" id="CLU_065416_0_0_1"/>
    <dbReference type="OMA" id="EFKVICM"/>
    <dbReference type="OrthoDB" id="3355826at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="296" mass="33303" checksum="08758DBF1250D15A" modified="2013-05-29" version="1">MSTTTPAPTQPHTWQDTTVHIEDRHRAGELVTGEFAKVLLDAAAVPPSTPQDLVVLDNACGSGIVTAILLGRMSEEQKRRTKVLCGDIQSEVVKYVTERIEREKWEGVEVKLLDAQDTKLPSSTYTHVLTSFGIMLLPKPILALQEIHRILAPGGLNAFSTWVEVGWVAWVERAFRAIPNCPPFPTQEQISNFMDTGRWDQESFICQVLEEQRFVDVRIQVHKEAGKIESPEFLVRVFGSMFIGLATRWWTDEQKKEYADEIAPVLLSQLQEEFGKGQQVTMPMCANLITCRKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ62</accession>
    <name>M5FZ62_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_100106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628696.1">
        <property type="nucleotide sequence ID" value="XM_040767423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ62"/>
    <dbReference type="GeneID" id="63682485"/>
    <dbReference type="HOGENOM" id="CLU_1574436_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="19238" checksum="2FC2A542FF9FBACA" modified="2013-05-29" version="1" fragment="single">MRPPAWFHTSVERDSDRRAREDTNEEFALLPPLSHLPPTAPSPPAPLSPIPEHAASRQPSVTSTRITTSASSRTISPSPLGLHPSNFRMNPPAEGKKARRVQWARSEQGDERRAGNGEGEGVREREEDGVGVIEAGPDAQNLRERRERRREEERWERERLSRELDERGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZE7</accession>
    <name>M5FZE7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arabinanase/levansucrase/invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_116455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628137.1">
        <property type="nucleotide sequence ID" value="XM_040770205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZE7"/>
    <dbReference type="STRING" id="1858805.M5FZE7"/>
    <dbReference type="GeneID" id="63685267"/>
    <dbReference type="HOGENOM" id="CLU_016508_0_0_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18833">
        <property type="entry name" value="GH43_PcXyl-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="4">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="517" mass="57171" checksum="77AA61BE281C776C" modified="2013-05-29" version="1">MALDALRNPIIPGLNPNPSCVCVSGTYYLVSASLLYFPSIPVYTSVDLVEWKNVGYVCTRPSQLDTKDCNLKPGTPWPGGICAATIRYHGGVFYVTATLVYGDKQPTDSSRWQNFLFTCTDPTKHEWSDPLQIDFMGYDTSLFFDDNGKAYLQGLSCSRAKPEIQQMEIDFATGNSPRGSPKTLWKPESGTYIEGPHMYRNDGFYYLLFSEGEDSNTLGTALMRSSTPWGPFDSSVSPLLPSPPNVLRPTGHTELVHSPTGWLALFASPRQGTEVSSLGPEAHLLPLTWPSGEWPTLGPALPVNTPTQTTTDVLALPPLASTSLPLSVLTIRAPPPASPYRRIGPSLILRSDEIPLPTAESPSLILLPQRRQRSTWHFILAWPGNGPSYDVGPIFEGGVTVYLDWKRHVDFAIIRNLVWTGQARVRIVGPQCTVSGRLDIDLPARLRVETFKDGYEFWAMHKGEWKKIDVVDVGLVSGDRYGGVAIGPFLTSHEAIEMYVQEWKVETHEELEGKTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZL7</accession>
    <name>M5FZL7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_59902</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the importin beta family. Importin beta-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623845.1">
        <property type="nucleotide sequence ID" value="XM_040775590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZL7"/>
    <dbReference type="STRING" id="1858805.M5FZL7"/>
    <dbReference type="GeneID" id="63690652"/>
    <dbReference type="HOGENOM" id="CLU_008136_1_0_1"/>
    <dbReference type="OMA" id="AQEGAMS"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000028">
        <property type="entry name" value="Transportin-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="324"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT96947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="911" mass="100588" checksum="37A5C8312D75B17A" modified="2013-05-29" version="1">MAEQWVPQAEGLHHLVELLKKSSSPVSEERQVAQQQIEQFQSIADYPCYLVYILTHGKGELETTRTVAALVLKNNARMLLKSPSPVVEYVKANVLESVRDPSSMIRTNSGTLIASLLALFEPQNWPQGLFYLVAALDSPDVGAREGAIDALDKLCQDFPRKLDVEIGGQRPLDYMIPKFIAMTSDSSPRIRQHALNAIAQFALIESQSFNANIDGFMACLFRCAGDSDPDVRRMVCTSLSILLRERSDKLVPEISNVASFMLYSMQDKDESVALEACEFWLTFAEDMDLVDALRPLLGNLVPALLQSMIYTEEDLAMLEADIDDTNVPDRDSDIRPQHYGAKSHGVGEGQSDTQPAFKSRDAGGAEEEEFEDYDYDDDDDEFVSEWNKRKCAAAALDVLAVRFGADCLATLLPLLKDRLWHQDWLIRESAVLALGAIAEGCMDPLEPHLPTILPYLCSQLQDPKPLLRSIACWSLGRYAHWCTVNIEQNQYFIPALEGLLHTVLDNNKKVQEAGCSALATLEEEAGPGLAPYLEPIVQNLVTAFSKYQHKNLLILYDAIGTLADSVGEALNRPACIEVLLPSLEQKWSALQDDDDDLIPLMECLSSVTVAAGPGFSPYAPAIFQRCLRIVHESLVRYQTFVQNPDLDEPEKSYLIVSLDLLSGLVQALGELLAPMITSSDPSFMTLLAASLQYPQPAVQQSAFALIGDLAIYCFSVLKPFLPSIMPDLISQISGEPRAEYVSVCNNAAWSIGEVAIRCGPVDPDFAQYVQPLLQSLVPILLHPKSPKSLTENAAVTIGRLGYIFPAVVAPHLDVFAEHWCQALGDIKDNAEKDSAFKGFCALILNNASGISKAFVPFCNATAKWQAPSLELNSMFQQIFSGFKSMLGENWEPQMAQVPEPTRSVIRQRYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0R1</accession>
    <name>M5G0R1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-mannose transporter</fullName>
            <shortName evidence="5">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630735.1">
        <property type="nucleotide sequence ID" value="XM_040772318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0R1"/>
    <dbReference type="STRING" id="1858805.M5G0R1"/>
    <dbReference type="GeneID" id="63687380"/>
    <dbReference type="HOGENOM" id="CLU_025360_1_2_1"/>
    <dbReference type="OMA" id="VWMLINC"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="378" mass="41218" checksum="FEE2D6A1CC677487" modified="2013-05-29" version="1">MADQKSPAVEYKPVPTKEEEKRPGSVGEKATNPVFPILSYCCSSILMTVVNKYVLSGRHFSMNFLLLAIQSIVCVSVVATLKRTGVISFRDFDMKDAKNWFPISFALVVVIYTGSKSLQFLTIPVYTIFKNLTIILIAYGEVLWFGGHVTGLTLVSFFLMVLSSIIAAWSDITNTINALTGVWSPIDQTSGTPLPEGIAAVGSVPVNLGYLWMFLNCLASAAYVLGMRKRIKATGFKDWDSMFYNNLLSIPVLIVFSLLVERWTSENLTLNFPPESRNFLLFAMVLSGGVAVLISYTTAWCVRVTSSTTYSMVGALNKLPVAASGMIFFGDAVTLGSVSGVTTGFLAGVVYAIAKQNQSKTEKAKQGEGGIPMYTRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G167</accession>
    <name>M5G167_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_116157</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629373.1">
        <property type="nucleotide sequence ID" value="XM_040770147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G167"/>
    <dbReference type="STRING" id="1858805.M5G167"/>
    <dbReference type="GeneID" id="63685209"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OMA" id="QIRLGNC"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="530" mass="60014" checksum="8A944135E34AF3D5" modified="2013-05-29" version="1">MIYLFDILALGVAAWLAYKLALYGRREKNLPPGPPTTFLLGNIPDIPSKKAFHAFAGWAREYGEIYSLKLGHKTTIVLNSPAAVEAIMEKGSRVTQDRPKMWLFDHYMYDHDHLIFSSVPSKVYQLRRVFATFLNQTTAQSYLPIQNAESCQLLYDIMFQPDGFFTGVKRFTISLMFSLTYGTRASRIDTPLAALYYEAADKTNELLADRSASLDFVLILRVMPSWMVSWRKQTDCLNAQERQLTSELMQKLSSRRKARQVGTNSFMEQILDNSKEFGLTDNMMHTLPLLILQAGADTTACAMLSVILLLLGQDDVLAKAHAELDAVVGRHRLPVLSDMEYLPYIRAIIKESERLRPTNPLGFPHAATEDQTYAGYVVPAGVTVLCNTWALGHDPTLFTDPENFSPERWLDPADRHADTWPFGISRRVCPGMHLARNSVALVITRLLWAFDIKKKIDPMSGCPIEVDTLDYAEGLVLCPNKFQADFILRGRESAETIRHELREAIPQLEMHEGSLEQSDKDHIQHMRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1L9</accession>
    <name>M5G1L9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TRM5</name>
        <name evidence="13" type="ORF">DACRYDRAFT_88387</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1L9"/>
    <dbReference type="STRING" id="1858805.M5G1L9"/>
    <dbReference type="HOGENOM" id="CLU_443443_0_0_1"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="58"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="253"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="414"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="583"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="315"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="616" mass="69699" checksum="D9280D4069422829" modified="2013-05-29" version="1">MLLSSDREDEIDPEGLAFIKDRAIELLPYDIKLTYDFWDSNDILSTILPPDVVVPNSFTSMGHIIHLNLRAHQLPFKHLIGEVFLSKSPGMRTVVNKTDKIHAQYRYFEMELLAGEPDFMVHVSESRHTFMFDYREVYFNTRLGTEHDRIVSKLSGNGLVCDVMGGVGPFAIPAAAKGCAVMLNDLNPAAIKWAKLNVEKNDVSDLIRLYEMDGVDFIRKSVIDAFKKPFPPFKPRIGRQERKRLEWLEEKKEKKRLAKPLRAPSLNRRNDGQGTSRGRKTDNVFQSPISRPQNDARPSSPTSSRTPKTPLLMNPTVSHRNPPSPPQDRSFSTLETPVTSYTDQAQRPDDESRESPSTSPADLDVVDAAPDEEPQTSDDVQSTQTTAPDITPPLSEAMSHLPTVSKLSAIPSLSDPAAVIPPSTKSVPRPKYSPSSNPQSLPDLPNGMERRTPTHYILNLPTTAIQFLFAFRGLLRPIMETHLMAQYYSPTKNMPMIHVYCFTNALDEDSMRADILKRASDQLKYPLTLDMPELELHYVRKVAPTKTGWCLSFRLPWAVAIENVSEAEIRVLQDELRKIHEDMEGLPDDDDAYEENPIFPDARKKDRKEFPKVDMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G278</accession>
    <name>M5G278_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629688.1">
        <property type="nucleotide sequence ID" value="XM_040768352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G278"/>
    <dbReference type="STRING" id="1858805.M5G278"/>
    <dbReference type="GeneID" id="63683414"/>
    <dbReference type="HOGENOM" id="CLU_1855208_0_0_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15487" checksum="4E939D745E29103B" modified="2013-05-29" version="1">MPLLFFRPADFLICICNTSFPHLDTWTPVNYPGVSSDENWISAITHGSFFWKAWTEVLMTERNMHVDTRCKFYGLKTGNMIPPSGSPFRQQTTLRPSPFLGYRRAYLGAGGKQDAPTNIKADTMLIGLPFLGCVPGHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2M0</accession>
    <name>M5G2M0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_50663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629833.1">
        <property type="nucleotide sequence ID" value="XM_040775000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2M0"/>
    <dbReference type="GeneID" id="63690062"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OMA" id="FAYWVNI"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="22"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="532" mass="58533" checksum="A93BB97EF8942735" modified="2013-05-29" version="1">MSRAATTPPETSAWANRKCLILCSIVAVANMQYGFDSAAIGSLQAMPGFLAVFGYPDPSLPTGYGIDSTVQQLIGSLMTAGAFLSSLVAGAFSDFLGRKYALWAACILNFIACAVQIASSNVGVLYFGRLLLGFANGFFVTFSNVYCAEASPAHMRGVMVALFAYWVNIGAIFGSVVDNYTSTRMDKLSYQIPIACLFIVPVLLGLGLFVVPESPRWLLVRGREAEARKSLDILRGGSTEQQWTEYEWDEMVRGVAAEKEIAQGVAWQDMFRGADLRRTLLCYGMIGCQTASGSWFIIAYSTYFFQIADITKAFQFSIMNTCIGFLGVNCGMYAIRHIFGRRSILILGAFLVGVSHLAYAIADTVHPNTEETGQIIVAFMALFQFSYNGGVGAASYPVATELVSSRLRAWTVGSATALGYILAWTTSFCTPYFINPQDLNWGAKYGYIWAASNAVCIVFFYVYMPEMKGRSLEELDEIFEARVPARKFPEYVCHISQEAAHDVATHHIPHINDKPSIEYVENTVEEKYTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2R5</accession>
    <name>M5G2R5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624950.1">
        <property type="nucleotide sequence ID" value="XM_040770665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2R5"/>
    <dbReference type="STRING" id="1858805.M5G2R5"/>
    <dbReference type="GeneID" id="63685727"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="OMA" id="IGISECA"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="32842" checksum="E65833BFB61F2982" modified="2013-05-29" version="1">MSPTDMPTRTLGHARVSAIGFGAMGIGGYCYGSDVGSDEQRFKVLDRAYELGCRFWDTANIYGDSEELIGRWFAANPDKRKNIFLATKFGIRNSAIAEQTDSDDSNPRVDGSPENVRLSCELALKKLQVDSIDLFYIHRIDARIPIEITVQAMVDLVKAGKVRYLGLSDPSSLALRRAHAVHPITAVQVEYAPTTLDIEDPKIGLLQACRELGVKVIPWSPLGRGILTGQYKSADEFPPDDYRRILPRFRPENFPKVLKAADTLKEIADNHGATAGQVALAWILAQGDDFIPIPGTKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2W7</accession>
    <name>M5G2W7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629464.1">
        <property type="nucleotide sequence ID" value="XM_040771089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2W7"/>
    <dbReference type="STRING" id="1858805.M5G2W7"/>
    <dbReference type="GeneID" id="63686151"/>
    <dbReference type="HOGENOM" id="CLU_552091_0_0_1"/>
    <dbReference type="OrthoDB" id="3419629at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55716" checksum="E12189600B5AA8EE" modified="2013-05-29" version="1">MDAPQSTNYQSQTKSFKLGQHNAVHQYKLWMPTGNSITLPAGSAPADPLVSGIICSREQQVTLSAEHCPILRSQLARQVPGSYRDMLESEDPPSEEEDVVLAASPAVEAEDQEEQEQEQEEQEQEEQEQEQEQKQEQEQEQEEYKEQEKEERQEVGQKEMSILYISDDESGKEHAVAPQQAVEDPKGKKHCAHGLSNLGELETSPVQKTPAKCQKYPTHKVDDFLGTPGKIICPTLGLVIQDLLVHQGNLQVNHLQMGSRQHIPIQSDCGQLPKSGIWQLAQSVTSWCHPLLDYMHEWYKVKPTNGEEVNTFSTLIPGGGVSDWHMDGSGVIMVIIHVSNLVEKGPKKLWLMAPQTERNNAILAKFLYARKKHMLSAAVIPFLENIQYVLVTPRTLEHTAFFLAPGMWHCMLTFDISAHVAFLIYDVRLWLQAQKVMESNIKRVSGLIGMAEQAEQVEMMIEELDAWREVGAPQRWAKEARAGLSSWLAMLKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2X2</accession>
    <name>M5G2X2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Chorismate mutase</fullName>
            <ecNumber evidence="3 12">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_21390</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13898"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="3 12"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629938.1">
        <property type="nucleotide sequence ID" value="XM_040772375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2X2"/>
    <dbReference type="STRING" id="1858805.M5G2X2"/>
    <dbReference type="GeneID" id="63687437"/>
    <dbReference type="HOGENOM" id="CLU_057757_0_1_1"/>
    <dbReference type="OMA" id="ATCDVNC"/>
    <dbReference type="OrthoDB" id="191918at2759"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.590.10">
        <property type="entry name" value="Chorismate mutase, AroQ class superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008238">
        <property type="entry name" value="Chorismate_mutase_AroQ_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037039">
        <property type="entry name" value="CM_AroQ_sf_eucaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01802">
        <property type="entry name" value="CM_pl-yst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145:SF12">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017318">
        <property type="entry name" value="Chor_mut_AroQ_eu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="Chorismate mutase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51169">
        <property type="entry name" value="CHORISMATE_MUT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="13">
        <location>
            <begin position="162"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR017318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU03044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="310" mass="34530" checksum="0787E35AAF92CF3D" modified="2013-05-29" version="1">MAQTNLLSADPLSLETIRGTLIRLEETIIFSLIERGQFALNPTIYQKGAVAQLKELGFQGSWLEWFLAEIESFHAKARRYTSPDEYPFTSNLPAPLLPPLQFPTIFHPNTVNVNPTILNFYIHFILPRITANATQALAAKKRAEGVQGAAEWEDDGNWGSAATVDVSVLQAISKRVHYGKFVSESKFRSKPSAFIPHIQAGNRQALEDLITKPEVERALLHRLRKKASLYGQEIGPDGEPLVNGKNGVNGTNGHAENEKAKAKIDADVVVEIYESWLIPLTKEVEVDYLLQRLDGLSEKEIEAFMSQPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5G314</accession>
    <name>M5G314_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_15286</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629509.1">
        <property type="nucleotide sequence ID" value="XM_040771094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G314"/>
    <dbReference type="STRING" id="1858805.M5G314"/>
    <dbReference type="GeneID" id="63686156"/>
    <dbReference type="HOGENOM" id="CLU_014931_2_0_1"/>
    <dbReference type="OMA" id="AFQNVMR"/>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="372"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="471"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="569"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU02615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="715" mass="79848" checksum="3B8B63124C908872" modified="2013-05-29" version="1">MFPFSIRVARCDDGTHSPAQDGATDKTSVASKAIEAVKQKVTPPESELRRWRRTFETHAKLTGTDGQKYLDIENFVNAIAPPQDLSKITRGQYALLFRVADVNRRGRLSFDDFHVFETLLKRPDADYWIAFQYFDADRSGAIDYDEFKNVFESCLGPEALPFNFDCDWVKLYLGRKDGAHVLGYNEFTQLMKGLQGERLRQGFAYLDSNKDGFITPDQFKRIILELAGHKLSDEVIERLPTLTTLNPGKGISYSEVVAFYNVIRDMDMVERFSSIIREAVAKSSDGRIAASDFLTAASQSTRYALFSPMEASIIFHFASRGAAGASNRLTLIDFAKLLDPRWQAPVAFNRPVDGEGSKGRWTSLAHFARDFGHSVYNFGLGGIAGAFGATMVYPIDLVKTRMQNQRTTVVGELLYKNSLDCVRKVYRNEGFLGFYRGLGPQLIGVAPEKAIKLTMNDLVRGYASDPETGRISLGWELVAGGVAGASQVVFTNPLEIVKIRLQVQGELAKSQGAKPRGAIHIIRSLGLFGLYKGASACLLRDIPFSAIYFPAYNHFKKDLFREGYNGKKLTFWETLAAAAMAGMPAAYFTTPADVIKTRLQVEARKGQSTYNGLVDAGVKIFREEGGRALFKGGVARILRSSPQFGFTLVAYEYLQEWFPYPWQDKPQRLETQYTLAAGEDISRTRARNALKILLDVHHDIGRRGTTPAEQRRSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G317</accession>
    <name>M5G317_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629988.1">
        <property type="nucleotide sequence ID" value="XM_040772387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G317"/>
    <dbReference type="STRING" id="1858805.M5G317"/>
    <dbReference type="GeneID" id="63687449"/>
    <dbReference type="HOGENOM" id="CLU_053354_1_0_1"/>
    <dbReference type="OMA" id="FALSETH"/>
    <dbReference type="OrthoDB" id="3355622at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025444">
        <property type="entry name" value="Monooxy_af470"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13826">
        <property type="entry name" value="Monooxy_af470-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18810" checksum="0DC74B62C0E83688" modified="2013-05-29" version="1" fragment="single">MAKSVDTYLQAKGWKKNAQMEGVIRNKFTAQLPPVQGEEDTPGAQGVVVFILGARINHPLGFMAPGVKELGEWAQKCYKELEDKYDEYGMLGMSTYLGTSRASGNEILTLMYFRNTYGLHTFALSETHRATWNWWLAVQKKYQHMGIMHETYDVPPRHWESVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3D0</accession>
    <name>M5G3D0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_34709</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631610.1">
        <property type="nucleotide sequence ID" value="XM_040774384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3D0"/>
    <dbReference type="STRING" id="1858805.M5G3D0"/>
    <dbReference type="GeneID" id="63689446"/>
    <dbReference type="HOGENOM" id="CLU_029507_6_1_1"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="10009" checksum="C4C639BCEF4E8665" modified="2013-05-29" version="1" fragment="single">YSFQTLVGKVVLIVNVASRCGYTPQYEGLQTLYEKYQPKGLEIVGFPCNQFGRQEPGTDADIASFCEMNYGITFPVMKKSDVNGDEANEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G404</accession>
    <name>M5G404_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627469.1">
        <property type="nucleotide sequence ID" value="XM_040770311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G404"/>
    <dbReference type="STRING" id="1858805.M5G404"/>
    <dbReference type="GeneID" id="63685373"/>
    <dbReference type="HOGENOM" id="CLU_523756_0_0_1"/>
    <dbReference type="OrthoDB" id="2447803at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="58934" checksum="C31C8B6E0EA93CFE" modified="2013-05-29" version="1">MEPSIFQQNDVLHLICGFVPPRTLPKLARVSRLLHYSVLPYIWKKLDQRTIACLTRGIDLTAQLMSHFKLHASLVQDLTLDFYLQRRFRPSLIIALDEIAEHAPATESVLPNLRRFRICASEASDLTYTHYFLGPSLYQLEVGCSGFNNQITDDGHSEKVVTELLLAIKSRCTNLHTLSFRGMPWLRDLPLVEQLLASLSTVTTYDGDGVVLSPNLLNPLARSTKLEDLKILMRPAQYDVIDPWGDLPLDGVYTDVLPLLENLRDVISPASFPYLRHIELNCDIQVATALLSFLHSTLQTITVVCSNRRGLIAQSDLDSLVDIMTTFATSLHDIDMTIIEPFDPLMRRGMPISWKTFAPFLRCSEIERFRLVYDSSDNFDFSQSSEISRAWRNIESFYLDWDPPARHRTKCVNHTGLHDPRSLSIVDMLQFAFHCPGLRNLLVAWLDASGSLTVPSNLPTVMWPLTLGVGYGQMECAPNVADFLRKVRPNVQLECRASYGPEGPRTAWKKVQELLKATRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4T4</accession>
    <name>M5G4T4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_28794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632160.1">
        <property type="nucleotide sequence ID" value="XM_040774305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4T4"/>
    <dbReference type="STRING" id="1858805.M5G4T4"/>
    <dbReference type="GeneID" id="63689367"/>
    <dbReference type="HOGENOM" id="CLU_024456_1_0_1"/>
    <dbReference type="OMA" id="GENTNFY"/>
    <dbReference type="OrthoDB" id="331341at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44414" checksum="89BB620A66ABAD4F" modified="2013-05-29" version="1" fragment="single">FEDTVDASLEVSARQAKRSINTDGYESDSTDDGECVVMSRRSGANEMGDEDDDMFAPSGSAGKEGTKNEAADDDDDDDEEYGGGSKKEKVLELGDIEGQEFGEAGGGQSDNEDDDDEPVDEDEAERRAKKGMGFELTGFNMKEEMEEGKFVDDGTFVRSRDPHEMHDRWLEGTSERDMKRARKAHEKREKEEREREAREMREQQRKGKEEYELELVQLMRRGESVMETLQRLGAEAKKAGGQKHKAKRKPAGIAAASMDIDGDTEPSTTPIERVTALASTLMELGNMDVYDDTYEQLLRSVRRSGLVSQNWVPPSQTPPRKASPPLDNTQYEYRWSPDYLAVAGGSVEGPQTFGPFQKRDLDAWRSAGYFGGYENCERVQVRGVGDSEWKSWNAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B9</accession>
    <name>M5G5B9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630324.1">
        <property type="nucleotide sequence ID" value="XM_040769888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B9"/>
    <dbReference type="GeneID" id="63684950"/>
    <dbReference type="HOGENOM" id="CLU_024327_4_1_1"/>
    <dbReference type="OMA" id="YQHSTIQ"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF2">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="403" mass="47094" checksum="190D7D4AF5AA14EF" modified="2013-05-29" version="1">MSTGSTRLPWRSNQPRRRPRRTFFLLSLFLCALLFFPLRGPLRTWIRTYNQIPSGSFSPSAYHGCAPISALHQPREKGAILLLLREKDLAQLLPTLANFEEKFNAQFRYPYVMLSSPDEPSFSAHFRAQVALSLPDGAEVEYAEIEDHDWRIPDWLNATEMREGFARQGREGVQYSGREGYHHMCRFYSGLFARQKVLEKYEWYWRLEPGVRFYCRISYDPFRFLALRNQVYGFVITIVETPNTIPTLFRTLSTYATDHSLVPGALWPFFTKSKHGSMEGEYNMCHFWTNFEIGDLRFFRGHEYQDLFNMLDKKGGFYTERWGDAPVRSMALGMLVEPERVHYFEDFAYKHDWFMHCPPKEMGCECDCPAFGDGYTDIDRDGWYSCLPEWRGVQGEAKGGKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5I5</accession>
    <name>M5G5I5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630379.1">
        <property type="nucleotide sequence ID" value="XM_040772214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5I5"/>
    <dbReference type="STRING" id="1858805.M5G5I5"/>
    <dbReference type="GeneID" id="63687276"/>
    <dbReference type="HOGENOM" id="CLU_1081909_0_0_1"/>
    <dbReference type="OrthoDB" id="3354982at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="172"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="29201" checksum="02B81DC6ADF5BD02" modified="2013-05-29" version="1">MSPPSAHAVVHDDSVSPTSASLSPLNSSMHPLEPTSGKRIYRCQECQKVFSTSGHLTRHSKVHTGEKNHICPYPDCQRRCSRRDNLLQHYTMHLTKEERDLPTTYVREALSAMQARMGTYVHPYPRGATAAGPPPQLPPMRVERSLQQHVYPIPTSYPTHRYPEHVAYARHEHHTQRPVLLTSSPSPVKRPLELDMDDDMRRPPSMRRTSSSSSGSTREPITPPMPGAPRMNMTKKEYLPQMPEERRFQVSSVRGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J9</accession>
    <name>M5G5J9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_116899</name>
    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
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        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63685343"/>
    <dbReference type="HOGENOM" id="CLU_089401_0_0_1"/>
    <dbReference type="OrthoDB" id="10261040at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="198" mass="20515" checksum="FB068B0990B7642C" modified="2013-05-29" version="1">MSLTLQSLQLHTQTPQDAPPMLATLNLLYPSSSTSLASSFSPETLTLHPPASLPPPAAATQLRGLVLAAQKVASQAIIGSVLAGGGSESDEYGDIGLWIPSPDSTTLGAQEIGQELVKQLQLTVWSGAELTPRPPSLPLPWETIPAPVSKPLLEGLAQLQEPVSFTLQLDGAEGDTPVVLLGKMEGGWGGLIAAGVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5S7</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_24166</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626010.1">
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    </dbReference>
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    <dbReference type="GeneID" id="63688641"/>
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    <dbReference type="OrthoDB" id="10332324at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="11828" checksum="FB60E0B498295693" modified="2013-05-29" version="1">MAQWLVAKILPKAVPLPRGSYSTMDGDKPSKPMNWDIPPAGVESGLEAAKADWAQRVSSRMASSGMAPSSRFPSSTGVPRSRDVSLESRRVEGSLQSVPQTRETSTERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5W1</accession>
    <name>M5G5W1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99202</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630494.1">
        <property type="nucleotide sequence ID" value="XM_040777576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5W1"/>
    <dbReference type="GeneID" id="63692638"/>
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    <dbReference type="Proteomes" id="UP000030653">
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="26556" checksum="1218C6D8A1956AC6" modified="2013-05-29" version="1">MMSLHLTPKSILKRSGFPHKPPSNSGSIRRSVSFCSEDSVRMADSYDRSPASPTTELSWSDIEELRRLQMDSDSDDSMDPIDEAKTLMDLPALLAAAPTALLPLLPPINAISRPVPTLTLPAPRNRGANGGGCWLAPPKRSASLLPVTAPIRTRPLLAFLPLLPVSDGSSPSPMYARPDPNAIPYFSPRPNRGKDADSPMTDDSSSPITPPDTRRMHPLEMAQMDAVGAGSFEITFKRRMESDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6I0</accession>
    <name>M5G6I0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acid phosphatase/Vanadium-dependent haloperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_56129</name>
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    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626270.1">
        <property type="nucleotide sequence ID" value="XM_040775357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6I0"/>
    <dbReference type="STRING" id="1858805.M5G6I0"/>
    <dbReference type="GeneID" id="63690419"/>
    <dbReference type="HOGENOM" id="CLU_019266_0_0_1"/>
    <dbReference type="OMA" id="ADDCPCY"/>
    <dbReference type="OrthoDB" id="301434at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="10">
        <location>
            <begin position="116"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="554" mass="61731" checksum="F71BC3D20E7D79F8" modified="2013-05-29" version="1">MTTLQVPTPAYAQSLLSSRSSSPSSGGEKTTTVILEPGTQPDYVYDNALPPWRAAIRRWVVKSLRWESECIANMQRVVRRPWLDTYFVYTSTLGTHTFFMTVLPAFFFFGYPTCGRGLVQILSFGVYTSTFVKDSICSPRPYTPPVTRLTIGTHHLEYGFPSTHSTNSLSVALYIFTLCLSLPPWGLAITSALLSFYIFSIVYGRLYCAMHSFTDCIAGCLIGTLIWSIQWAWQDRIEQFMAIKGPLGKPRSEPRSEWSCTVPTITILMGLLLINQHPEPVDDCPCFEDAIAFVSVVMGTTLGRWHGSQAGLDAESGFFHSLTPGWQLANLNDWLTFFGFALLKMLVGIAAIFLWRLVMKTVLLAMLPPFYRIISHVVTLPTRRFYTPATQYTSVPQENGLHLTPSLIDIPTSEPGPKHSLHASIASGSIAKQRGAQNGREKWPAPVNDVEISTDRFNVVKHYDASVITKVVVYAGIGWISSEMLPAMFEIFGWGVKSGGRQWFAICLSTRSGSSSLRFAGDGHTVWRRIGNLLHQAGYNGWLVHVFVRICTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G790</accession>
    <name>M5G790_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631493.1">
        <property type="nucleotide sequence ID" value="XM_040767935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G790"/>
    <dbReference type="GeneID" id="63682997"/>
    <dbReference type="HOGENOM" id="CLU_541873_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="503" mass="54215" checksum="4781B3466B0AC92C" modified="2013-05-29" version="1">MSGILPAPALSGATASAEVEVCEDVVSLPPPSPRTVSPMAVSPAVPTPPSLPMAGGALAPSSSIIHTDDNPSGTSASPPAVIPMDDAPTALVVLSNNLAPSSAIPLNGTDLTAVVLSNNPPSSHTGWGEPSGSPLVGWGTSSGRDSSAGWGDPADPPESALIPWDEDEEEFVDDDEDPYLVPYGVSLHPKDDRGTSYGRDAQGFPRPQTPEYAWGSTDPFYCDACAYASEPFPLLVGNPHANSRLALHSTEQLFDRLHRWTAEETCDCLALDCEDRSDELFCLCHEHINQVKGLEDALRKSKEDLVPSLEENARLSSTLDNTRQLCSTAMKMISNAQQLASQARLDTEHFHRDRDNWRSEYDYIHGHLHSSSDHTDPARAPSTMGAASMSLRLRPASSHETPDNHNVPMDDPIVKEPASAPPQPSTVAWQASRCGRAHLCTSAQSTVYIDGNGIFWCPHPEQVLQLGCVQCCWTASHSRPDNCHGNIWLLWSSYSFCVDSAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7I8</accession>
    <name>M5G7I8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Multicopper oxidase 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_109838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626630.1">
        <property type="nucleotide sequence ID" value="XM_040768951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7I8"/>
    <dbReference type="STRING" id="1858805.M5G7I8"/>
    <dbReference type="GeneID" id="63684013"/>
    <dbReference type="HOGENOM" id="CLU_006504_7_1_1"/>
    <dbReference type="OMA" id="AGAYWMR"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13857">
        <property type="entry name" value="CuRO_1_Diphenol_Ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13886">
        <property type="entry name" value="CuRO_2_MCO_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="109"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="244"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="487"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="619" mass="67152" checksum="02089567B0906601" modified="2013-05-29" version="1">MADTANVEKDSIEVLPKGPTGAPRRRYRVYFLGGALLVVIVLGLALGLGLGLGLKNRNFNSGFASGSGNSTVTYNVTVPTADNFLLPDIRNDPPQVRYFSLVVSESYGAPDTFARPMLVVNGTYPGPTLLANQNDRLIITVYNQLPNVSTAIHWHGLYQNTTPFYDGTHGISQCGIPPGQSLVYNFTLNGWTGTTWYHSHYQTQYTDGVLGAIVINPSNATVDADGRPANNPPQPANPVQWDADFVVIIQDWYHTPSQAVLALYLGPNGPDGTAGDEPTPESGTINGQGQWYGGPYANFALQAGKTYRFRLINSGSLANVRFSIDDHPLTIVSADGVDTEPLEVAGVQIAVAQRYDVLVHTNQTTGGQWWMRGTVLTDMFTYSVNDAQYDHRAILSYPVADPSSSPQPGSADPGPGVAGLQDLSTTDWFSLVPAVRQTIPEPDFQYPLEISFSVYEDTNYYGYMNSTSWVPLEGESTLTLLSTSRFISALVNGPSIPQGQLIVTTTSVQTVDLLITNLDDGDHPFHLHGHRPWLLAAGDGRYAGQALNTTDTVLMRDTHVIAHFGYAVLRFVTDNPGMWAFHCHIAWHMGAGLLMQIASQPQVALSYGMPQEILAQCAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Q4</accession>
    <name>M5G7Q4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626705.1">
        <property type="nucleotide sequence ID" value="XM_040768842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Q4"/>
    <dbReference type="STRING" id="1858805.M5G7Q4"/>
    <dbReference type="GeneID" id="63683904"/>
    <dbReference type="HOGENOM" id="CLU_010595_9_3_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="29190" checksum="9CA28A7D70DE00DE" modified="2013-05-29" version="1">MSSHGTDEETKYLLGNADTRESDRLDKQHRIIQDLVGPLLPEDLKLRKNYHVLDSGAGTGAWALELHSTLNPQTYVFITGIDINSRFFPASPSPNVNFVVHSIMVLPPAWTERFRFIHQRFLSAALSFADWRIVFDQMHRALLPKGWVRVEEFSATLCPTNVSAQKLPYSHQLLDYAGKFAKKAPLRMGPGDEYRGMRANFTNIWLYIRDSMKGHPGAMTDADFESLMANLSKELEENDVGWNLHIVTARKPGIARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Y1</accession>
    <name>M5G7Y1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633210.1">
        <property type="nucleotide sequence ID" value="XM_040767733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Y1"/>
    <dbReference type="GeneID" id="63682795"/>
    <dbReference type="HOGENOM" id="CLU_1578473_0_0_1"/>
    <dbReference type="OrthoDB" id="3173670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="169" mass="18995" checksum="F5481CEF0C45620A" modified="2013-05-29" version="1">MSHSQPPKKLPQIHLMVKTHKHTLALTLVPTQTIQDLKAQAIDALSQFSSSPEDEKEAGFPLRPELGDFEVMRRNGDEYDVLEEKETAMGLRLMAWDRLYLAWRDSKGKLLPVQHDKFSFWGEDDEEPAPSSSTKAAVNSGVGPKANAGAKGKRKMEDDYEPDEDEMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G840</accession>
    <name>M5G840_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_48318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631199.1">
        <property type="nucleotide sequence ID" value="XM_040774823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G840"/>
    <dbReference type="GeneID" id="63689885"/>
    <dbReference type="HOGENOM" id="CLU_2312738_0_0_1"/>
    <dbReference type="OMA" id="PEWIENG"/>
    <dbReference type="OrthoDB" id="3366922at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="100" mass="11288" checksum="38D5B44328F0FD76" modified="2013-05-29" version="1" fragment="single">LQQKLQNSKVVNGVTHAFLLGIGRLSYADPPEWLDPENVKRVTDMRDQARDLFEQVIEDPLEGDSVWAAYQDDGEDSTSGTESEQEPDEPEQPDIPMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8G5</accession>
    <name>M5G8G5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bet v1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_97925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633400.1">
        <property type="nucleotide sequence ID" value="XM_040777492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8G5"/>
    <dbReference type="STRING" id="1858805.M5G8G5"/>
    <dbReference type="GeneID" id="63692554"/>
    <dbReference type="HOGENOM" id="CLU_061635_0_0_1"/>
    <dbReference type="OMA" id="SYFVWAR"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="35"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="34466" checksum="065CC4455D5F3EA7" modified="2013-05-29" version="1">MSFPQPTDPAPNGYIPNPYTALLEIALAKVQTETTSSSGWSTIGTQEDVLLEKKYTDSGLPIVRGKGVVQGTLPREMLQAIALPGCRERWDARFETGFSLEKYAQSEGKFYTGQKGTWPVSGRDIVGAQATKFADDGSWVQNVQTSVPDTDQTPPVNGKVRATLDFAGWTLMRNGDDTEVTYVVHINLNGSIPAWIQDRIATEIPLCVAKARDFYLAAGAPPLVSTLKKTELCQETFTFDKKEWQAVFLSKGDEEFNIAVDEKRMFRDGWEARLEGDEAGNVQLIKRQGELVVKVAPEASGKKFELVVGPASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8I9</accession>
    <name>M5G8I9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_74020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633425.1">
        <property type="nucleotide sequence ID" value="XM_040776043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8I9"/>
    <dbReference type="GeneID" id="63691105"/>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OMA" id="MATIWKV"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="48"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="595" mass="63600" checksum="2B3217C62ED37EFE" modified="2013-05-29" version="1">MDSTVSLEKSDDRFATVRAVPLPSSGASEEGGYCARSKPKRGAAFWLIFSAASTSVFLSALDASCVSTALPRIVADLDGEASFAWVGSAYTLASAAWLPLSGALAGTFGRQPIMILALSLFFLGSILCGEAINMNMLIAGRTVQGLGGGGILAMTEIIIADLVPLKERGLFMGITSLVWALAAAIGPPMGGALSQNVTWRWLFRINLPLTFIAICLVLAFLKLKVPSGSIMQKLRRIDWLGNALIAVSTCAATIALTRGGVEASWTAAQTLVPLILGLLGIIVFFVVEATCVAEPTIPFDLLSNRTSVAGFLTTFFHSVVATAIIFYMPVFFQACFGASPIQAGVDTFGLAFTIAPAALVGGVSAVLTKRYVPQNWIGWILLTIGTGILSLLRVDTPTASWVGFEILTAVGLGLIWTSVKFPILAPLPVSRNASAMALFTFSRTFAQTFGITIGSAILQNELMTRLPTAFLTLFPGGVDVSFGAIPYIPTLPSPIRDQVQDAFADSLSILWKVMLAFCFLGLLTSLMMREIELHEETDENWDLSASETEIEMKPHVRTPSSEAVETTPLTPLENDFDQGVIIIGPMYPYDQERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G987</accession>
    <name>M5G987_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_47111</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631654.1">
        <property type="nucleotide sequence ID" value="XM_040774740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G987"/>
    <dbReference type="STRING" id="1858805.M5G987"/>
    <dbReference type="GeneID" id="63689802"/>
    <dbReference type="HOGENOM" id="CLU_004414_0_0_1"/>
    <dbReference type="OMA" id="HEMFLFG"/>
    <dbReference type="OrthoDB" id="26399at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <keyword evidence="6 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="10">
        <location>
            <begin position="113"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-T C-terminal" evidence="11">
        <location>
            <begin position="370"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU04760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1102" mass="122716" checksum="9692548A20507195" modified="2013-05-29" version="1">MQQQLLSAIRVAQDPVSDPALKTAAIEFLTYARDKADDTWPAALVLFMASDLATGARVYDPQTRYFALEVLGAFLDIEGPEELSPAVFRPLQVTFTPYIESEYINGTAESGAPYLRNKFSHTLALLFTRSYPDLWPTFITDLIGAMRTIPGSGGSQGTALNLNLCTLMLRVLNEVSGEIADQTVRGARTFSIGRQNRETRLKHNVREKDASNVITALVTVVTEGLDRLDSQGGESAEREQVQELVTLAVQTFASYVHWLDINLTVTPVTIPMLYRLINHPFLPFRVAASDALYRLISKGLQDPRDKLQLIKVLSLHQSLNNLEQQTRRPDRTDEQDDELHFRESLGKLLGIVGMELLRIPEDKTVTDESVKGEAQALVATLLPIALRFLADPFDDVSESVFPFLTQLFVYYRRQRKNLKDGFPLDSREAFFTEFMSVIIQKYQWDKDTEWGIGEDDEEPDDDDMAAFGELRKGLKSFMDGIAGLDVDLYTKATTEVVRSTLGAFVNGQQLSWQRVELALQLLYLYRELNKADKKLGKDKSGFCVMPASLPKGAKKSIDFNSLPLNPLGEMMVMLMDSQICNFAHPAVTIQWAETVCRYCDFFKLRKAYIRNVLEVFVGPLGAQNPKNNVRHRIFYLLDKFVQETSSDIPSDLISPLLASLMQVMNIRPEIPDDDSDLGEAELLFNATANSSSFNALLYLFEAAGTMIFRAPAEQQISFLQEFTTPLLVEMQQALQTPRNGPRDVLPILTVHHIMMALGNLAKGFPDMPSGGAPLMQTVLCQVFGQVAEGVLVALQSSSQYRVIRDAARFAFLRILSATGPTVQPFLPALLTTILSQIENGEISDFLNFMGLVAHSLKEDVRETVADLATPLLTHVNTVLNQPEEGTDDVVVHNEIKRAYLQYVNALVGSPLFTIFASPNNMGAFETFMIFLMRLAEIPSEPQAQKLAFIILSKAVAAWGVNPALPSTNGTSTPNGTNGIVRAPPSTQPIPGFDRFIYDQLIPLAFRVPLNPDLRFKDAETTLVLAEVTALLNTIVQVRGDEALTFLTTYIPSLGMQPEFVQEFPGKVGGDKMQFRKWFADAMRQRRHEERIGGTVTPSAPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9T1</accession>
    <name>M5G9T1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Amine oxidase</fullName>
            <ecNumber evidence="14">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_20598</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="13">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="13 14">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="14"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631944.1">
        <property type="nucleotide sequence ID" value="XM_040771998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9T1"/>
    <dbReference type="STRING" id="1858805.M5G9T1"/>
    <dbReference type="GeneID" id="63687060"/>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_1"/>
    <dbReference type="OMA" id="QDGNIEC"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000006">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 14" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="17">
        <location>
            <begin position="99"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="16">
        <location>
            <begin position="249"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="12">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="13">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU05050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="686" mass="77095" checksum="03D85A82FBD8F7A7" modified="2013-05-29" version="1">MTAVSLSIRQHTASQTEIKALKFMNTALLPPPKLQVLAYLGIPLETGQPPEPKPDKLERRAESQFINPVTGDAYNANFTLVDGAWKVDSVELLPEGTQPSITLEELCLSESVLRKDARVCALAAEVGVTPEQLHADGWSIGLDERWPRRKRLQQCLLFARYHKDDHLYAHPLDFFPIIDSNLMEVVHIDFAPHRLDPSNPPSSKVPPLDAKLERPRIPPPQERHEYLPELMQGQEGFEGMREDLKPLFVVQPEGVSFKVEGRELEWQKWKMHIGFNSREGLTLNTITYTDGGVVRPIAYKLSLAEMVVPYAEPLYPHPRKFAFDIGEYGMGTLANELSLGCDCLGTICYLPGCFVSHSGAPVIVKHAICIHEEDAGLLWKHTDYRPGGRAQSVRARKLVVSLVATVANYEYIFYWSFYQDGAFELEIRLSGVLNVYLLAEGERAGRYATEVAPRIDAQYHQHLFSLRLDPMIDGIKNSVMETDVVASPYPTGSEENFAGNAFTTNSTVIQTTSEGERQWNADTDRRWTIINPNRKHYASGQPVGYKVMNCAFPKLLAQPGSWVRRRAPFARSSLWVTRFKEDRNWPSGKYVPQSGAAPEDSLVGWMKGDEKVDNEDIILFFTIGTNHIPRPEDWPVMPADMMRVTFKPVSFFRQNPALDVPSTSAQGSMYAFGAAQEHVGVSSHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9X0</accession>
    <name>M5G9X0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632508.1">
        <property type="nucleotide sequence ID" value="XM_040771773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9X0"/>
    <dbReference type="GeneID" id="63686835"/>
    <dbReference type="HOGENOM" id="CLU_3032291_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="55" mass="6314" checksum="B365D963C0F3C9E6" modified="2013-05-29" version="1">MHLSPAAPRHRPHRPHQLRSGPFRLPLVKQGPDGLVFEMEADRHPWISATVRQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA99</accession>
    <name>M5GA99_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RmlC-like cupin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_113787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632633.1">
        <property type="nucleotide sequence ID" value="XM_040769701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA99"/>
    <dbReference type="STRING" id="1858805.M5GA99"/>
    <dbReference type="GeneID" id="63684763"/>
    <dbReference type="HOGENOM" id="CLU_045717_0_2_1"/>
    <dbReference type="OMA" id="TPWHPHR"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="185"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="33940" checksum="A5DF9A86C9579B38" modified="2013-05-29" version="1">MAAAASAVHASRSVVNKVFAIEQAEGVGARVRRSIGSAKLRNLSPFLMLDHFDLSTRGTGFADHSHRGQATITYMLQGSSQHEDSEGHSGTIEAGGVQWMTAGRGVTHAEMPVHGLGIPDPKGLQLWVDLPKEHKMTKPTYQELGKAGIPSAFPEGPDGPSEIRVISGKSYGVESPVKPLGGCWYFDVQLKKAGASVFQDIPAGWTAFLYVLSGKVKVGATPEAHEPYHTLVLSSKSNEDGVALTAEEDNTRIVLCAGEPLNQTVFQYGPFVMTTKEEIMKTLQDYSMGINGFEKAHVWKSKIAENLRRSMGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAG4</accession>
    <name>M5GAG4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22758</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627800.1">
        <property type="nucleotide sequence ID" value="XM_040772940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAG4"/>
    <dbReference type="STRING" id="1858805.M5GAG4"/>
    <dbReference type="GeneID" id="63688002"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="VYETNIW"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="31651" checksum="50C1C02AF9E653B2" modified="2013-05-29" version="1">MNNNNPDNLKPVVLITGCTKGGIGYSLCESFAPHASVVYATSRSLGSMTPFPRGNIKCLELDVTSDESVQAAIGRVLEEEGRVDVVVSNAGGMSIGPILDADIPELKRSFDTNVFGTHRLARACIPGMLNRHYGLFVLVSSVTALTPGPWHGIYSAGKSALLNYGETLALECAPFNVHLQLLIPGAVRSNLSLNESSRWPGLPPGSLYSPWEKAVRERMVVSQSEGVAMDTQLFAQRSVERMIRGWRGKKKLGRRVVEGGMCWAYWFVGMWPRAWQLAFIWWLQGKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAP4</accession>
    <name>M5GAP4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_53713</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627890.1">
        <property type="nucleotide sequence ID" value="XM_040775194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAP4"/>
    <dbReference type="STRING" id="1858805.M5GAP4"/>
    <dbReference type="GeneID" id="63690256"/>
    <dbReference type="HOGENOM" id="CLU_001265_51_2_1"/>
    <dbReference type="OMA" id="GESYWML"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="20"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="443" mass="48005" checksum="AA2E36E2FE0C850F" modified="2013-05-29" version="1">MSRLLTRGGRPWGLRWRSSVNYLTFVVSLGIGADTLIYSLPVAVIPFQLAEWGYMDLSSRTGWLLFAFASGICIGTPLAAWLSERYKTRRLPMLAAIVALIGSIIMFMLAPNYVLLVVARVLQGVSSAVIWTVGVALICDAVPPNRVGQQMGTALIGLSLGSVAGPPIGGALYAKYGFYAPFYFGVALAMLDLVTRFLAIEPQDARKWVNHLSQLPTGNDSEEKSPDASGPVIPVPESDASGETVTDEVGSQRPILEMLRHRLTWVGAFNMLAYGMVGPSLNATLPLRLWDVFGFNSTIVGLIYIAIVVPTCFSGILSGRLADKFGSKWVAILCFAAAIPWSGLLIIPNLPLDIICLAWQSFFLNGCVSPVMRDFFTVAIEIKGVGFAHVYAIFNMSYAIGTPNMYDHLSHGWLAVCIFWIACTVSGVLVTFIFSDQTEKGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB89</accession>
    <name>M5GB89_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_50281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630196.1">
        <property type="nucleotide sequence ID" value="XM_040774983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB89"/>
    <dbReference type="STRING" id="1858805.M5GB89"/>
    <dbReference type="GeneID" id="63690045"/>
    <dbReference type="HOGENOM" id="CLU_003703_1_0_1"/>
    <dbReference type="OMA" id="MIESHCH"/>
    <dbReference type="OrthoDB" id="3257613at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="1">
        <location>
            <begin position="53"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="27220" checksum="6B6FFF8D430E229B" modified="2013-05-29" version="1" fragment="single">CTWCGQPMQLTMRCRDCFQAPPLCVSCQVTSHVHNPFHWTEVWQGKFYACQSLCDLGLLICLGHNSVACPASLRPPSTLFVVIHANGIHNMLLGFCQCPRGPNHYIQLLCANLFPVTFDNPKMAFSYTVMKDFHLHMLCSKKSAYDYYAKLVRQTSDIVLASTNDHYQELLHASQIWMDLKASQCCGEAHDVNNNLPPFAASRICSPLCPACPQLSINISKEELAQADLDKLCILSESLFWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBQ1</accession>
    <name>M5GBQ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Arginine biosynthesis bifunctional protein ArgJ, mitochondrial</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="10">GAT</shortName>
                <ecNumber evidence="10">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Ornithine acetyltransferase</fullName>
                <shortName evidence="10">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="10">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="10">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">N-acetylglutamate synthase</fullName>
                <shortName evidence="10">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="10">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="10">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_49608</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="10">The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="10"/>
    <dbReference type="EC" id="2.3.1.1" evidence="10"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630386.1">
        <property type="nucleotide sequence ID" value="XM_040774917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBQ1"/>
    <dbReference type="STRING" id="1858805.M5GBQ1"/>
    <dbReference type="GeneID" id="63689979"/>
    <dbReference type="HOGENOM" id="CLU_027172_1_0_1"/>
    <dbReference type="OMA" id="WGRIVMA"/>
    <dbReference type="OrthoDB" id="2017946at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.340:FF:000002">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2330.10:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2330.10">
        <property type="entry name" value="arginine biosynthesis bifunctional protein suprefamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003802">
        <property type="entry name" value="PRK05388.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023318454" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023318455" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="10">
        <location>
            <begin position="251"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="10">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="10">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="10">
        <location>
            <begin position="250"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU03492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="475" mass="49345" checksum="9DB9FE342C7C5ABA" modified="2013-05-29" version="1">MSASASHDPVASGPSTPRRSPPSKDHLAHDIPDNAFPRSFLASGVHCGIKKRGGANDLGLVVSTAEHTSAAACFTKNVFKAAPVLVSQEVLLKFGGRAAAVVVNSGCANAVTGKQGMEDARDMVRTVDALREARTGGTDTADGVAQPVSAGAAPSKTLVMSTGVIGQTLPITNILNGIALAHANLGASFASWQGAAQAFMTTDTFYKLRARTFTLAGKKVRIAGIDKGAGMIHPDMGPPSPSTAPAPPHATLLGLIATDAAVSPSALQSALTFAVERSFNSISVDGDMSTNDTIVALANGASGMERDIDELADPELYTQFRDELTAFATELAKLVVRDGEGATKFVTVSVEGASSFSDAHTIASTISTSSLVKTALYGEDANWGRILAAVGAAPVSNPPDPQKVSVSFLPCDGSTELKLLVNGEPEKVDEVRAKQILQMEDLEIRVVLGEGGESARYYTCDLSHDYVTINGDYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC81</accession>
    <name>M5GC81_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrimidine 5-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632999.1">
        <property type="nucleotide sequence ID" value="XM_040769528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC81"/>
    <dbReference type="STRING" id="1858805.M5GC81"/>
    <dbReference type="GeneID" id="63684590"/>
    <dbReference type="HOGENOM" id="CLU_059493_0_0_1"/>
    <dbReference type="OMA" id="YPHHVNL"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="27779" checksum="1A6903FE9FEB3002" modified="2013-05-29" version="1">MAKPVTERVMADDRYIVWLDIDNTLYTRSSRIAELMIERIHAYFLSMGFTDDDAHELHSKYYTQYGLALRGLMKHHNIDALDFDKKCDGSLPLEDILKPDPKVRKLIEDIDRSKARVWALTNAYSTHANRVLRVLNLSDLIEEIFYCDYSSPDFSCKPEPSFYAQALSTAGVTDPSKCLFVDDNLNNVRAAKSCGWGHCVLYSEREEDHSMSEHPKVEGVDAVIGNLQELRELWKQVFQVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC87</accession>
    <name>M5GC87_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Actin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_21201</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630616.1">
        <property type="nucleotide sequence ID" value="XM_040772285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC87"/>
    <dbReference type="STRING" id="1858805.M5GC87"/>
    <dbReference type="GeneID" id="63687347"/>
    <dbReference type="HOGENOM" id="CLU_013085_2_0_1"/>
    <dbReference type="OMA" id="FKEPRGA"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11819">
        <property type="entry name" value="SH3_Cortactin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="10">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="591"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="701"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="313"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="479"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="652"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="659"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="760" mass="80539" checksum="5BB7DD764A95E70A" modified="2013-05-29" version="1">MSLQLNLNSPEITEAYKEVLNGDPSTNWVLYTYEGRSNDLKVQDTGSGGLEELEDSFNDGRIQYAYVRVKDPNSGLTKFVQINWCGDGVPESRKGLFHTHSATLTDFLKVVHVQVAARSDADVDPDNIMKRVADSSGSKYSVHAEQAKAPEPIAPIRGSGYQPIGKVDIGELRKGAKPAEPIAPIRPAYQPVGKVNIDDLRQGAKPEGPIAPVQGSGYQTVGRVDIDDLRRGARPEEPIAPVVGSGYQAVGRVDIAELRRGARPEQPPAPVIGSGYQPVGKVDIAELRRGAKPDVPIAPVGTAYTPARDELANFKNLANPPPPPAAPRPTPPAASRPVPPAAPRPAAGGFDPRPVIATHAPAPRSPAPTKPAEDDRIGPVGTAYTPVSLPAPRKLVNPFANRMQQEEKPVVQSPTHTGPKKLTWSERQALAKKQQEEEDARTRSLAPQTTSSSGRVADTVVAGPGVAVSGVRSAMHALTDAVSGTVSPPPPPPAAPRPPLPGRQETAEPEEEEWPEHEDAGPPMPTSVPAAPPPPPSAPRPMAVVEPEEEAAPPPPPPPPPPPPPPAPPAPEELENVTTQVATMQVAESHPAGPRAKVMFSYEAAEGNEVDLVEGEVIYGVEQLDEGWWSATTAEGKTGLFPANYVELIEDDAETEATAPPPPPPPPPPPPPAAEPVYEEPAPPAPPPPPPAASRPVAAEPAKPFAIAQYEYEAAEENEISFAEGQKITDLEFVSDDWWSGRVEGGPTGLFPANYVELHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCF3</accession>
    <name>M5GCF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_94052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630751.1">
        <property type="nucleotide sequence ID" value="XM_040777193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCF3"/>
    <dbReference type="STRING" id="1858805.M5GCF3"/>
    <dbReference type="GeneID" id="63692255"/>
    <dbReference type="HOGENOM" id="CLU_000288_103_2_1"/>
    <dbReference type="OMA" id="AMVPWED"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="110"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="415"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="457"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="497"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="577"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="660" mass="73311" checksum="E7CCB2A706F4882B" modified="2013-05-29" version="1">MDTPHTPLWAHIHQPRLAHPQPSSIPHQPPQDPLPPSHSLPLAPPTPAPSPRPTSPEPSSPLLGPSTSYLNTFPLLPTRQQRAFLTSLIPLLTSDHLRHLNALITPLLQRDFLRDLPIELALHVLRLVDDPRTLARASQVSRTWRALLLDEHMWREMCRRHGFDAHLSTADVLRIRHQEQQAAYAQEHILSPRPMPALTPPLPPHSPPFSYRRHFVLSFLTDANWRRGGRLLITHPPSPSSPPPMAGLDLAPLGAVPGIPLLPQPHLFQPQPGHVHAHHHPPQPAPQTTENVVTSLAMDDDYIVVGLANCRVHVYNARSGALFRTLVGHESGVWCLGLASATPREEFISGWKSPATPSVEKDSEETWNEEQRRNMSDPCGASRGWGNPGPVVVSGGCDRDVRVWDVESGECKHVLGGHSSTIRCLKLLHDRSIAVTGSRDGTLRVWDVQRGQSMHVLAGHQHSVRCLEVWGNLVVSGSYDCTARLWNVDTGECLQIYRGHFHQIYAVAFDGERVVTGSLDSTVRVWTARNAESVQMLTGHTSLVGQLQLTSTHLATGGSDGRVMLYALPSLAPLHRLLAHDNSVTCLQIDHRFLVSGGNDGRVKLYDLETGTLIRELTEPCEAIWRVSFGRERCVVLCKRDGRTVMEVLNFRPEEGELNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDW6</accession>
    <name>M5GDW6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_106812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629647.1">
        <property type="nucleotide sequence ID" value="XM_040768340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDW6"/>
    <dbReference type="STRING" id="1858805.M5GDW6"/>
    <dbReference type="GeneID" id="63683402"/>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OMA" id="INRACEV"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="307" mass="32903" checksum="04209A2BBBF40A4E" modified="2013-05-29" version="1">MPPSAPPPGIYVPTLTFFQPTQKQELDLQALTSHIARLAQARVQGIVLLHPIGEPHHLSRDERTHLLTHTQHFLSSIPAQLTLIVGCSAPSTWETIDLCEEAAALGGAYCLVNAPGGEDELGDSALEGYFFDVADQSPLPLLLSPSHALPLPLLQRLAQHPNIVSLLLTSPSLALQLSSTFPTKSFSPMATQSDALLPMLCAGAQGAILPLGNVAPEALVQIWESWNREDLPAAQALQRPLARCGAIERAGTRGVRAALSHVKGYGGWSRRPVLAPGEKEREEINRACEVLEGKGKSRPGMPNGVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDX8</accession>
    <name>M5GDX8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_106844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629682.1">
        <property type="nucleotide sequence ID" value="XM_040768348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDX8"/>
    <dbReference type="STRING" id="1858805.M5GDX8"/>
    <dbReference type="GeneID" id="63683410"/>
    <dbReference type="HOGENOM" id="CLU_016053_2_0_1"/>
    <dbReference type="OMA" id="FVYGHYG"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF461">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="105"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="529" mass="58037" checksum="A26CE16EC5C3D10A" modified="2013-05-29" version="1">MAESTEEDIKAPVDPEVEVTVMKRIGNKPPIEELLYYANIQRETYTEGHDEKGMSQFTKVLNWADEKKKEHSVNVTVTPLELDDTLSEREREKLNAHRALRTAGWAAMFYLITTDILGPFNAPYAFSTVGYVGGVFLYALFGIGAGYTSLLLLYMYLRLDSDRYPVRNYADLVEVVAGPIARRFATAGQSIQLIVIVATVILGNGQALFQITQSQLCFIVSVLIFGLLGMCIGQIQSLKSVAWVGSASVYLNISVILISIGFFANSPPNYVGANAAYGLPIDPPAPIEHVAIVDGTLANKVNGAMNMVYAWGGMMIFPEMMAEMRRPMDFWKSIACAELVIMIVYVMYGIVGYSLQGQYVLPLAYQGVSKYAWQSVGNAITLLTVTIAGTLYSNIGVKVAFMVIVYWAVAFVIASSIPQVQTLQGLIGATFLMQYSYTFPFAFDVIVDATKGDPTYVPGQPHKRSDTWRDISRWKRGLFTGRVWFKWMNFILALAGAATACLGIYGAVITIQVTFANGAATSFGCAAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GES0</accession>
    <name>M5GES0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RA-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_114911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630422.1">
        <property type="nucleotide sequence ID" value="XM_040769907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GES0"/>
    <dbReference type="STRING" id="1858805.M5GES0"/>
    <dbReference type="GeneID" id="63684969"/>
    <dbReference type="HOGENOM" id="CLU_016105_0_0_1"/>
    <dbReference type="OMA" id="WFIGKVP"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="6">
        <location>
            <begin position="440"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="579"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="679"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="513"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="745"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="366"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="373"/>
            <end position="392"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="418"/>
            <end position="428"/>
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    </feature>
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        <location>
            <begin position="757"/>
            <end position="789"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="819" mass="88523" checksum="D6CF36496B48F982" modified="2013-05-29" version="1">MVPLLYKAKWRTHAASGSGGEQHSPRSSSSCPSPGITRDINEWDEGAVYQWMCTLGPGFEQYEKKLKENGITGDTLVLLNQDELKEIGISSVGHRLSILKAVYQIKVAQHIPIEPDQYVPPSESIASATPPPTEPQEQPMYERILALIEQQNTRLAALEQENYRLHESLDELLSKSNGGLPSSDSAGAQEKQLRRQPSVKWAPYGSDTSPAADMPDFPHLSPEAAEHDIPGRFPGDRKTPTRADRPSSARERQFPRGERPPSRNDLRRPSTSAGHSSGLSTPVSGRPDIDRPHSRTDGRPSTSGHTPSSASLTPNTDRIPGRPSSRTDIREPERRPSTSGAALPTASLSPEYARSPQSAVSQTSGEENMLTPITTITTSGSIMSSGLPSSIPTASGLMPHSALPHSATGNGSRSKGSRRGDGMRDRVGSLHSLEDPCWKVLPAALKKYNIKDDWQQYALFISYGPAGGDRCLNYDEKPLLLFSQLKERGKNPVFMLRHIKDIKSPIAISEEKAAKRSSASKVEHGGVATNGPLPSPLPPSKGDRPPQLLRSKASMGLDQDEMEGGHGALRQGDEIETLEEPVSTIAIYPHIAEQADEFDVKMGDSFIILQRFKGWWVAQRDLSGDGVVDPTAERGWVPAGCLLELTSTRSLAFARLSRNGRTPNGDPALIPMMASSITSTQFPAFALKDYQASGKYELTLRKGDALRVFKRYNHWAYAIKDATGERGWYPSWYVARSFSSGGVPDHVSSGTLTPRNGTPATTPATGPGEGPSPLSAISTTPTTPTYASTESGSAVDEQAPSPLTITYRTLGRSQAAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>M5GET9</accession>
    <name>M5GET9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase</fullName>
            <ecNumber evidence="15">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">DACRYDRAFT_77228</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="15"/>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630477.1">
        <property type="nucleotide sequence ID" value="XM_040776257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GET9"/>
    <dbReference type="STRING" id="1858805.M5GET9"/>
    <dbReference type="GeneID" id="63691319"/>
    <dbReference type="HOGENOM" id="CLU_004844_1_0_1"/>
    <dbReference type="OMA" id="EGIMIKH"/>
    <dbReference type="OrthoDB" id="151490at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 15 20" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="18">
        <location>
            <begin position="371"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="675"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="894"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="762"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="774"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="805"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EJU03583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1006" mass="114615" checksum="6D41BA679003778D" modified="2013-05-29" version="1">MSVPPSPPASPKASAYPENHQPLQFERPPHVFNRGTSPPFTLLTALFKDLGKAKPPKRRDALSKWFHKWRTDVGNDLYPAMRLLVPQCDKDRAVYGLKEQAMAKIYITVLELDPKSNTATRLRNWKKPNFTESGTGDFPSVLYDCIKSRVTAETTLTIDEVNSLLDDLSASTKVQAQAAVMSRIAERCSAEDQIWIARIILKDLKIATKENTVFSVFHPSAFEIYNSTSDLKQVCWKLYDLHCTANNEDTEIQLFHPFQPMLCKRPRRELQDVVKLMGRKEFIIEEKLDGERIQLHKRGKEYYFCSRKGKDYTYLYGQHVGTGSLTPFIDHAFDDRVKNVILDGEMLVWDPVTEHYLPFGWLKPAALNKSDDPTKMHPCFKVFDILMLNDQRIYRWPLHKRKDALRKVFQPVPNVLEYAYETRGRTAKDVKTELERVMDDRGEGLVVKNPDKPYVLAGREDAWLKVKPEYVDEMSETVDVLVVGADYGTGKRGGGVSTLICAVRDDTMSGNDPQQVIFSVNEHADDRARSFLSFVRIGSGLSMSDFEEIRQKNWREYTPGEELDFVKLADRGTEDKPDVYIRPEDSFVITVKAAEIVTSEKYAMDWTMRFPRCRAIRRDATWEDVMTVKEIHDMRTGGRKREASSDPSRNKRRKVNQQLVLPASSMGTNVKNIQVKNDLFDGLRFVILEGMENHDKSMLEKLVHEGGGKFQQLLKGDDLIVISSRLGFPKANAAVKKGFDILTPRYIVDCVDQEEVLPRQNYLTAEQSETEADHDERATDEMEIKKDEDEDHKRLSEVQEHPEDAGSDTEISDYQEPEDHDIDEPTDDEDYSARPPLDEAVVGGVSKVQISAPQPSQEVNPRLVKDEHIIEDATGTKAQTSQEAMDEDEPAEDDTEKIFSHLVFYLDSPANAQNNALTSPETVKSSIVAKFDSLRPLILEYGGKITDDIHDTRITHIIVDKRDKTRISELRSITQTGNKYRQQVTADFVTDSIDDGALVSESVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFH7</accession>
    <name>M5GFH7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_76479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631037.1">
        <property type="nucleotide sequence ID" value="XM_040776206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFH7"/>
    <dbReference type="STRING" id="1858805.M5GFH7"/>
    <dbReference type="GeneID" id="63691268"/>
    <dbReference type="HOGENOM" id="CLU_017375_1_2_1"/>
    <dbReference type="OMA" id="CTHTKVK"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="65"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="8">
        <location>
            <begin position="167"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU04143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="343" mass="38648" checksum="CA6353B6FA8E3773" modified="2013-05-29" version="1">MSSAAQAASGSRPPALDESMTSRDYYADSYAHFGIHEEMLKDQVRTLSYRNAIYNNRHLFEGKTVLDVGCGTGILSMFAAKAGAKHVVGIDMSNIIDQAQKIIEVNGFKDKITLVKGKLEETELPIQEFDILISEWMGYFLLYESMLNTVLLARDRYLKPGGLILPDSATLYIAAIEDQEYKEEKIAFWDDVYGFDYSCIKDIALREPLVDTVELKAVVTNPYAIKHIDLTTVQVKDLAFTSPFSITATRNDYVHAFLAWFDISFGSIHKPVKFSTGPHAKYTHWKQTVFYTRDTLTVSEGESINGVLTCAPNARNNRDLDINIEYEVQGAVPSQDRIEYKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFQ1</accession>
    <name>M5GFQ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_44494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633396.1">
        <property type="nucleotide sequence ID" value="XM_040774581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFQ1"/>
    <dbReference type="STRING" id="1858805.M5GFQ1"/>
    <dbReference type="GeneID" id="63689643"/>
    <dbReference type="HOGENOM" id="CLU_067630_0_0_1"/>
    <dbReference type="OrthoDB" id="9995831at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="292" mass="32271" checksum="D84BBC0E27EACC51" modified="2013-05-29" version="1">MLIPVTVYENPLLTADSRTLILYLYALTHKLSSLGVPRLRLSSFLPFLSHDHPKPFPLLHVWCEVIETCESESFDGARMAMLEQTLHILFLPEWHTSTGRPSSTNSLVHHPGDNTGLSSPFHFQLHVITRLQFNEGGRIAMHRDFWGVCRLSALTLRAKGAMIDVRDLTEALFSFSTLFGWFARRLIAYNLIAFAWIFSLVPSFPRRASTSVPPHSFSHSAIPTPRARTRTSTYTGAGGAVSPILRTTTSFTREQEGILSAGLGLSFGAGARNMQVGDGAGQAPDTDRDSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG38</accession>
    <name>M5GG38_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_75734</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631707.1">
        <property type="nucleotide sequence ID" value="XM_040776155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG38"/>
    <dbReference type="STRING" id="1858805.M5GG38"/>
    <dbReference type="GeneID" id="63691217"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_43_1"/>
    <dbReference type="OMA" id="HFILLRC"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05578">
        <property type="entry name" value="STKc_Yank1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000639">
        <property type="entry name" value="Related to serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="285"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU04813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="425" mass="48788" checksum="F87B0BF5B9ECBD6E" modified="2013-05-29" version="1">MGAVCCRPEPIDFDGEVNLFHFALLRSVGKGAFGKVRVVQHKQTKELFALKYINKAKCVKMRAITNIIQERRLLEEIDHPFVVNLRYAFQDDENCFFVLDLMLGGDLRFHLDRNGPMSEELVRFYVAELSSAISYLHDKRIVHRDLKPDNILLDERGHAHITDFNIAVHYSPKKLMTGVAGSMAYMAPEVLTKRGYSYQIDWWSLGVVAYELMFGKRPFKGNTNSNLTQSITKDSVKFPEDAQQKHSREALHCLVTFLERDPRRRLGCKSLDDEAREVKSHPWMRDFDWDALEQKALTPPFVPDSKKANFDASHELEELLLEDNPLKARKRNANLDVNSLSSDQRTLEEQFTVYDYQKMNRRSYFNTSQQIVSQITANSSGPDSSRPPTPGMAELPMALTAEIDMSTKMMPVTRTQAMELASRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGA5</accession>
    <name>M5GGA5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="3 14">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_61546</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 14">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 14"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632042.1">
        <property type="nucleotide sequence ID" value="XM_040775674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGA5"/>
    <dbReference type="STRING" id="1858805.M5GGA5"/>
    <dbReference type="GeneID" id="63690736"/>
    <dbReference type="HOGENOM" id="CLU_037146_1_1_1"/>
    <dbReference type="OMA" id="PGQVLGC"/>
    <dbReference type="OrthoDB" id="1649088at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000006">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU05148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="519" mass="57000" checksum="BB02BFA5AB4C1CA3" modified="2013-05-29" version="1">MASASTHPVPRPKKRFIGRKAGTGRPISSTSSVVISSGIPVSILEDKSLNAAIAQLPSNYSFEIHKTIWQIRKNEAKMVALQMPEGLQMFACLISDIVERFTDALTVIMGDVTYGACCIDDYTALALGCDMLVHYGHSCLVPVDTTTIKTLYVFVEIGIDNSHLARTVRLNFPDDRAEFRRKLRDIEAAEVRGTLTAGDPITPAMQHLAITVDGEEDGRETHPAKDPTRLAIVSTIQFVAAAQALKEDLTTPLEPPKEDQTNERPAQEQAVVQRSEQQLHAGVYDITIPRAKPLSPGEILGCTSPLLPDVDALIYVGDGRFHLESIMISNPSVPAFRYDPYAKKLTRERYGHSEMRAMRGRAVDAAQKSLSWEDPDGDISNTVSTVEKEPVGWGLVLGTLGRQGNLQMLKALERQLSALSPSHRPDITPILLSELSPQKLALFPQLSAFVQTSCPRLSMDWGEAFPRPLLSPYECSVAVGGLRRWGDGAKGGEEGYRMDYYKGDAPWARSRATGSFEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGM2</accession>
    <name>M5GGM2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_75080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632627.1">
        <property type="nucleotide sequence ID" value="XM_040776107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGM2"/>
    <dbReference type="STRING" id="1858805.M5GGM2"/>
    <dbReference type="GeneID" id="63691169"/>
    <dbReference type="HOGENOM" id="CLU_014765_0_1_1"/>
    <dbReference type="OMA" id="HVIDMVA"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036121">
        <property type="term" value="F:double-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061749">
        <property type="term" value="F:forked DNA-dependent helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032042">
        <property type="term" value="P:mitochondrial DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18799">
        <property type="entry name" value="SF2_C_EcoAI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050742">
        <property type="entry name" value="Helicase_Restrict-Modif_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE IRC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396">
        <property type="entry name" value="TYPE I RESTRICTION ENZYME ECOKI R PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="311"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="720" mass="80206" checksum="FAFA8FC27D50C89C" modified="2013-05-29" version="1">MLSISWQLRRLSALFVTPIGLRVRPRCSSRCFLASAAVPEGAHDHSGSHRAVRLRPYQEECVQACFDAFSAGYSRIGVSSPTGSGKTTIFLSLITRMQPPADRLHATQALVIVNSVEQAQQTARAAAAMFPELWVEVEQGKHQATGRADITIATYQTLLSPNRLEKFTPENIKAVIVDEAHHAAAPSYRHILTYFDPALVINPKVEQGQSAVPVIEDDGSLQPPPGDPLCSKLPIIGFSATFSRHDGLALGKVFQRVVYHRDFLNMVKEQWLCNVRFTLVKAKLNLDHVQVNRTTGDFNPTSLAHVINTETINKLVVNTWLDRATGRKSTLIFCVDLQHVADLTNAFRHAGIDARFIHGGMRPVERQDVMKLFRAGEFPVLVNCAVLIEGVDVPNIDCVMLCRPTRSRNLFSQMIGRGMRLSPNTGKEDCRVIDFVDSVRRVDGVVNTPTLLGLDPDELVEDASLDETEYEIPTAEDQSDSPDEAHTLTPTSVIHIDYSDPFELAGSATGSPSLPVLSRFAWVACRKDVYVLECLGKGTVKIEPDYDEETGEISVFKGYFTPTVKRHDEDETTYYKKRLIVTGERLEATVKAADMFVVKQVLPPSMLALSYRSAAWRRQPATPQQLDFLRKRLEDSRKKLTKLAETSDSIARIVSHEENLSTLTKGQAGSIMTRLRHGSQSNWERKAISKAKLVTKRIKRKEKEAHRLAKQVVRVGPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGU6</accession>
    <name>M5GGU6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase epsilon subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_103051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in DNA repair and in chromosomal DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632997.1">
        <property type="nucleotide sequence ID" value="XM_040767703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGU6"/>
    <dbReference type="STRING" id="1858805.M5GGU6"/>
    <dbReference type="GeneID" id="63682765"/>
    <dbReference type="HOGENOM" id="CLU_010628_2_1_1"/>
    <dbReference type="OMA" id="FFCEGCF"/>
    <dbReference type="OrthoDB" id="10254730at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="297"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="547" mass="61032" checksum="D1371FBFE152D3C7" modified="2013-05-29" version="1">MAPPTLTSIEFQKKYMLALQVDAAQFILDILAEHSVGEDEVSDSLEHLAKGWMAQEYDSNLVTKPQIQRVYELLQVDSREVGGAGGAGTYALGEENELDPSQHLVFVDAFDMPRWMYSVERHTFEKSSTPPNIAGSPASRTAFLRDRYHVIKQVVLRNEHFTPAVVPGLSQGDTNKLTSTKNLLGCAGETFMLLGMLAHEPDGKLCLEDVDGKVLLDMSQAASCQGLITEGCFVLVEGEYTDEDTLKVWQIGHPPSERRGASRSIFGHIDFLGKGATTPAEDEEYARRIQDFPHVSFVVISDLWLDHPKTLIGLRSVLDRCVETGFTPFLFVFCGSFTSRGIGSGGAGIEQYTDNFSALGDLLASYREISAVSHFLFVPGPLDPWGSTTLPRPAIPEPFVARLKARLPRAVFLSNPCRVKFFGQEIVIFREDLMARVLRNLVGVKQEIEATELKRNLVQMVIDQEHLSPLPLTVQPILWEFDHALRLYPSPTALILADKYERYEETYEGCHVFNPGSFIGNSFGFSTYFPHTRRSEESMMDDVVNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGW4</accession>
    <name>M5GGW4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_112943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633087.1">
        <property type="nucleotide sequence ID" value="XM_040769534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGW4"/>
    <dbReference type="STRING" id="1858805.M5GGW4"/>
    <dbReference type="GeneID" id="63684596"/>
    <dbReference type="HOGENOM" id="CLU_009031_2_1_1"/>
    <dbReference type="OMA" id="PRTRFMD"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="280"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="709"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="767"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="311"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="737"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="787"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="830" mass="94155" checksum="F80E6652ECCE3C56" modified="2013-05-29" version="1">MAAENPGASSLTQLADSREDELWNADYVNEEHIMAFARALSAEDILEPESPVVSPLDSRRSPPEFRVRKVSAVSDFAPISTKVKRRKTPASHGRAQEWSYQIFRWPLLLILFLIIFAEFYLYVLIRQIVNVFEWVLAWRGRKRLLRRKLRSAKTYEEWKSAATMMDEYLDFNIWKHIDEDPYYDYQLVKKVRRSLRLHKERNDIRGLIGVLEVCLRPNFAGTENPRLYSETFYGTKILLESYVKEVESCLAFVRNSNEITVEERRRFFRDVNRGLGSSALCLSGGATFGYYSFGVIKAFLDANLLPRVIAGTSAGGLVAALTCTRTEEELRQLLVPRLADKITACEDPFRVWFKRLRQTGARFDTVAWARKATFFTRGSLTFREAYERTGRALNISVVPFDQHSPTKLLNYLTAPDCVIWSAMIASAAVPGILNPVVLMQKTKDGSIIPWNWGSKFKDGSLRVDIPIQSLNILFNVNHPIVSQVNPHVHLFFFAPQGSPGRPVAHRKGKGWRGGFFLSAAEQYLKLELTKNFKVIRDLELMPQLLGQDWSSVFLQRFDGSVTIWPKTRFMDWINILTDPDRKELERKMRVGELVTWPKLHMIENRFLLEREILRGRLAVRQTAVVREAGLGLTLDKVAAPNQPVNAIEKPTPDGDVLPERVRRKRQISIDSDAESGFNNEKGVLRRSRLSATSLPDDAVSVRSLPASFGSDWLNAPPVGPRKRRAGRASPAKGDNKLPSTSTTPAHPTRSPSFISRLRSPFVSAFAFHRSPHSTPPEIKEEIDETEQPLQDSSSSDTETDIAWLAERAAQASPSFMRLDDGAGMDEDDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH59</accession>
    <name>M5GH59_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_113314</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633562.1">
        <property type="nucleotide sequence ID" value="XM_040769607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH59"/>
    <dbReference type="STRING" id="1858805.M5GH59"/>
    <dbReference type="GeneID" id="63684669"/>
    <dbReference type="HOGENOM" id="CLU_004905_0_1_1"/>
    <dbReference type="OMA" id="NNRYARA"/>
    <dbReference type="OrthoDB" id="1936594at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="560"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="594"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="910" mass="103126" checksum="7D572A9878493AAB" modified="2013-05-29" version="1">MAITTQTALLVEKSLIEGKWRSEIDEFTAQLPIELAHLVVDGKFSQVLEHKEGRRFFQSPSSLNSSRSGRINDLLSPFAQGLEAELTRLAVAVACLHSFIQVNWTGPALDIKPVELLSDNSALTEEDLNRQSIEELCYGSEPAYHLAQVPTLFRLAQLLLEQPYDHITTIDWWRLRASSLHQHLLDEPVAFPTNILPHVDQLIKHLDGEPDLQGRLWIERGIAHHLVGSDTIAGENFINAARATGLQYEVSGALGRRTKFQHDAVTQLVLLAESRKRNDTVIDATSNDEEKPAVSEKPMQAEQKKDMPEALLLNDDTLLEHTKFTASSASAGALSHIDPQAQPALDPLDQCILLSLCLNVKNTSPVHGLTSEQMYAYVARVLSHPKNWTVYTMALLLRSRLEAKRTRTVERSTFQLQALIDQMPTSDSTLSERLLYFHSLILPSKWEMERELAVRYLSLGVVRSALDIFERLEMWEETVQCWQSLEKPEKGIAIVRDLLEGRKQEADVVLQRGKTTLEPQRPKLDKAREAKLWCLLGDLEKDKALEHYERAWEVSGGSSARSARSLGGYHFAQGNFKKAIPYLRRATQINPLYSRTWFVLGCTYIRTEEWVEAKMCFLRCVEIDQEDAESWSNLASMYLRMGEAGEKVELGSEDVPAEGEEEPKPEDKEALAGAIPFSNKLLAFRALKQGLRFSYENWRMWNNHMIVAVDVGELAEACRALGRVVEERAERDGESCVDMAVLERLVNAVTRVANNTVDGEDVRAARQNPNEGHGLKRRVTDLFTRIVLPRISNSARIWRMWARLLVWEGKWGEALDAHMNAYRAAVVSDERVEVDLENWKEAVGEVEEIVELMRNLGPRAAEEGKGGMKDWKFQAKSVVRTFMGRTKANFGDEPEWERLTELLVELRRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN88</accession>
    <name>M5FN88_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicle tethering protein Uso1/P115-like head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_112348</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623918.1">
        <property type="nucleotide sequence ID" value="XM_040769395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN88"/>
    <dbReference type="STRING" id="1858805.M5FN88"/>
    <dbReference type="GeneID" id="63684457"/>
    <dbReference type="HOGENOM" id="CLU_006318_1_0_1"/>
    <dbReference type="OMA" id="NICRESH"/>
    <dbReference type="OrthoDB" id="198977at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="6">
        <location>
            <begin position="456"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="6">
        <location>
            <begin position="725"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="931"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="993"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="841"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="931"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="946"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1014"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1029" mass="111994" checksum="DBBC77BB00C0D849" modified="2013-05-29" version="1">MDFLTSTYSQLRQTAQSQLSSALTPPSQSLQSTIDKLTDRLLQSSDIADRRASLLALKGLSRDAKREVGETALMALLGRLEEAEVDPEGGKALLETLLVLCERDDDLHSHPHPHPHPYPPPPNARGKGREDLGLRHTDVVLQSPEPVHTLVHLLGQSNFYVRFGALQLLGVLLQNRAVVVQGYVLTSPMGVGSLVGVLQERREIIRNGTPTPLGVALLLPRAHAPAEALLLLQNLINSNADLQKIVAFEGAFERLLDIAQQEGGMEGGVVVQDCLTAIELLLKFNVSNQNYFRETSNIPRLPPLLLFPSPPPPPTAPSPQSFALQFWDTQKLANAILLVRLVLLLLGGAGQGKEQNQLALLASGMTRALLELGLASNAPTSLKIHALKALSPLLANSKPNQELLGSLSLTPYAWAGGDEWDRLPQQASLAALVRTALSGDQGAAVLVGGVEAAREGLECRAAAVGAFDSFCQSNPAGIHLLLEELVFPPSEPSPFTDPPLPAGSLLLHTLTALPEPERAPQSLNGLPPARFNTYPTVFACHLFAHVLRSGEGAKAAARGVTLPLPPQAQQPEPEDEADHPPTLIQLLTGNVNLALREHTRAREEGREREAREWERAACAWLGVLCVWCWESAGSVREFLEEGGNVQVLVQPITQPSGIDPLVQGLAAFLLGTCYEYDTDPGEVTRCVFFSFLPGLPFLFPSPFLLLPPLSLLASPPPSLQMLAANPAHRATLHPILLKHIGADQFVNRMTRLREDDRFKQVTPDSGVVLSPGQDLHQQVQVQVQGQGQEQGREAEEEGEVWFDWAFVEFWKNTYFSVQRAITSDPNAVKPISGETQTLALISSLQGTIQSQAQDLETMQRKLDALHREREEEREALGSELDRLGAHVAEMGEELQLAAGRERSLDLRVGEREREVERLRAELVEAAFAPTSAPAAASVSPPARGGSQVSAVSSPGTETELKARLAELDRELKAAQAKLKEQEEQVEDAFVALDELSQKRKRDKGRMRQAGLVVSEDEEDEDKDEGEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNI0</accession>
    <name>M5FNI0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624378.1">
        <property type="nucleotide sequence ID" value="XM_040773910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNI0"/>
    <dbReference type="STRING" id="1858805.M5FNI0"/>
    <dbReference type="GeneID" id="63688972"/>
    <dbReference type="HOGENOM" id="CLU_1214719_0_0_1"/>
    <dbReference type="OrthoDB" id="2507344at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="228" mass="26103" checksum="BE8DF38A01DC0678" modified="2013-05-29" version="1">MSRVHSAPSLIRLGELEADGSPVFDPMLVERYLERLDRAKLSTLVAAHVTGGGVNRGTEFLSGKIHNDRLGIRNYHFMDRMVAYHTTYLKTRASGYAHDLNIRAYPERVTILFLKWSLAVKPLEEFLVNKVQGRETSLRARDYFANSEAGFLRTEHFSDTLQLMTHKHIGRTINLRQYRQIVKMILRDRVAGEDMDAFCAMDEENGRDDVDLQFNHSNSVAAQNYGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNK0</accession>
    <name>M5FNK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminomethyltransferase folate-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_84541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvT family. CAF17/IBA57 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624478.1">
        <property type="nucleotide sequence ID" value="XM_040776689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNK0"/>
    <dbReference type="STRING" id="1858805.M5FNK0"/>
    <dbReference type="GeneID" id="63691751"/>
    <dbReference type="HOGENOM" id="CLU_007884_7_0_1"/>
    <dbReference type="OMA" id="NMLVAND"/>
    <dbReference type="OrthoDB" id="191995at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="359" mass="40756" checksum="0199002930999814" modified="2013-05-29" version="1">MNRVHRFIRSTPLCRTYFTAPTVAPSAAIVPNRSLLKISSSDATEFLNGLTTRKVIPKPSAGIFSTFIHAQGRVLYDCFIYPVEDGFIIEYDRRPILSLRDYLRRYVLRSRVKFTDVTDQWSIYQLFGGYEPPMKWQWQWGPGGALEPVWEDEPAKEFPSALDRRAPGMGRRWLIPTGGKPPTSGQGYTEVDSMAYTLHRVMIGVPEGADEIVHGQALPFDMNLDMMGGIDFRKGCYVGQELLVRTYHTGIVRKRTWPVTLYRKGDEPPFTLMILPEGRRLPPPGTAIPIPGARGKGRLLCAYQNVGLAVLPLSKGEKSNGEVELALNWEEDPDWMIMPRHPKWWPTREGQHATLRSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP27</accession>
    <name>M5FP27_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Carbamoyl phosphate synthase arginine-specific large chain</fullName>
            <ecNumber evidence="13">6.3.4.16</ecNumber>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">DACRYDRAFT_102800</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarB family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="13"/>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623646.1">
        <property type="nucleotide sequence ID" value="XM_040767669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP27"/>
    <dbReference type="STRING" id="1858805.M5FP27"/>
    <dbReference type="GeneID" id="63682731"/>
    <dbReference type="HOGENOM" id="CLU_000513_1_3_1"/>
    <dbReference type="OMA" id="FPFNKFP"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000015">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000026">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="10 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="204"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="742"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="22">
        <location>
            <begin position="1007"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00074189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EJT96748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1129" mass="124021" checksum="430636BDDCAA32E0" modified="2013-05-29" version="1">MIQWSVTASRLTRLVYLKSTRAFHISRPVSIAPTKYAEAVAQSAVGGFDGDEHVLNSPSELARRISAKVLPKIPRPDVKKVVMLGSGGLSIGQAGEFDYSGSQAMKALKEEGIDAILINPNIATWQTSHQLASEVYFLPVTADYVAYVLEKERPDGILLTFGGQTALNVGMQLDRMGVLERLGVQVLGTPIRTLEISEDRELFVKALNEIDIPVAVSTAVSSVNDALNAAEEIKYPVIVRAAFTLGGLGSGFAENPDELRDLAAKGLSLSPQLLVERSMKGWKELEYEVVRDAADNTIICCNMENFDPLGTHTGDSIVVAPSQTLPDDEYHMLRTAALKTIRHLGVVGECNIQYGLHPTSKEYRVIEVNARLSRSSALASKATGYPLAYTAAKLALGYTLPELPNAVTKNTTACFEPSLDYIVTKIPKWDLAKFSGQVSRHVGSAMKSVGEVMAIGRTFEESLQKAIRQVDPRYTGFEAYVQPEDLDHALRAPTDTRLFAVAHAMYNKNYTVDQIHDLTKIDKWFLYKIDNIVQTSRQMTEAGTLQALNKDFMLIAKRMGFSDHQIADRVGCTETEVRAHRKVLGVTPFVKRIDTLAAEYPAHTNYLYTTYNAQEHDVSFDEHGTMVLGSGVYRIGSSVEFDWCSVTCARKLRDMGKRTIMINYNPETVSTDYDEADRMYFEELGWERVMDIYELEQAEGVIVSVGGQLPQNIALRLKHSGVTVLGTDPERIDSAEDRHKFSGILDKAGVDQPAWTEASSIEDAKRFAAQVGYPVLIRPSYVLSGAAMNVVYEESTLDHNLSAAASVSPLHPVVITKFIEGAQEVDIDGVAYQGKLILHAISEHVENAGVHSGDATLVLPPFSLDDGEMVRLKEIAEKVAKALDISGPFNMQIIRQPAENGQDAALKVIECNLRASRSFPFVSKVLGTNFIEAATAAIVGQNVPAPIDLMAKNRDYQAIKVSQFSWTRLPGADPFLGVEMASTGEIASFGRNMQEAYWAALLSTNGFKVPQAGRGVLIGGDTSKPEMAAVARSLVDLGFKLYCSSTEVAEFLNELPYVHCKRIFFPLKDKRKLREAFDEWEIQCVINLAKARGKDALDEDYVARRNAVDFGIPLINNARSHTAGGSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP30</accession>
    <name>M5FP30_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623656.1">
        <property type="nucleotide sequence ID" value="XM_040769403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP30"/>
    <dbReference type="GeneID" id="63684465"/>
    <dbReference type="HOGENOM" id="CLU_2158275_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="11846" checksum="020A58BA24FCAA24" modified="2013-05-29" version="1">MPVTKGSRMPSSAASRPQKKAGILGLPSLKFASTKLDSAAQVSLALTLLHLRRTGLFGFVPTVGSFSEPFDTPEPQNWWDAKKGGHEAFLTSLGKASFPALESVTLFNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQA7</accession>
    <name>M5FQA7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_82958</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625948.1">
        <property type="nucleotide sequence ID" value="XM_040776603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQA7"/>
    <dbReference type="STRING" id="1858805.M5FQA7"/>
    <dbReference type="GeneID" id="63691665"/>
    <dbReference type="HOGENOM" id="CLU_012441_3_0_1"/>
    <dbReference type="OMA" id="HYCPQVR"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="8">
        <location>
            <begin position="65"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="7">
        <location>
            <begin position="441"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="637" mass="71330" checksum="4C110FC024F1EF74" modified="2013-05-29" version="1">MPLPDSEEEEEDWPEETEIESDAGDQERQEEERRANNVATGARFGRLAPAAVLSLPSRTERVQRAKEQIASICQDIVADPENSLGLLRRLQTFTLAELPSPDVNAPAVPNDPLIRKLALLSLLSIFTDIVPSYRIRGLTEKEQAEKVSQMVARTREWEQGLVIVYKAYLGELEGAAKANNEMSDTAVRCLCTLLTDLTHFNFHTNIMSVVVARISRRSWDSNSELCRESIVRVFREDVTGQASLELVRLLNRMIKERKFRVRPNVLSTLLSLRLKTELGRPVDRREEQEKEGKGRDRDRDKGKKKGKKDKTYLSNKQRKALQETREIQKEMAEAEAQVDVEERDKTHTETLKLLFVLYFSILKSSPSAQNRLLPEALAGVSAFAHLINIDFFRDLLETLKKIARDADGEGDTEGGVTEEKEGEVRIGGAESELARKCRTKLLCVVTAFQLLTGQGEALNIDLAEFINQLYALLPVLGFVIPLEVDTVPLSTKATADNHNTKSAPPPSSVPSVTALLFRALHLLFLPSWHTSGTSSSHPPSRVLAFAKRLLALTLLLPPAPAIRTLEFLRQLRARESKLDGLFEEAEEGGDGVWRGEVDDPALANGAAARGWEVAWLAEKGEEKVREKARELVVWRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQE1</accession>
    <name>M5FQE1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin/actin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_84667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624561.1">
        <property type="nucleotide sequence ID" value="XM_040776693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQE1"/>
    <dbReference type="STRING" id="1858805.M5FQE1"/>
    <dbReference type="GeneID" id="63691755"/>
    <dbReference type="HOGENOM" id="CLU_027965_6_2_1"/>
    <dbReference type="OMA" id="MWLSRQE"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="438" mass="49376" checksum="3AB8A96F37CD9270" modified="2013-05-29" version="1">MAYGGDEVNAIVLDMGTYSTRIGYAGEDLPKVNMPATYGSVLDPDTGLFKHYVGDEGVNIYRPKMRLSNPMREGMIYEWNAVEDVLNYAFHSQLRCNTADHPILFTEPPWNNKWNREHLAEILFEKYQIPATFVVNNAVCSAFSAGKGTALVVDVGQDISSVTPVVDGYALTKSIQRQPIGMSLLTNTAYMTLTTPTLERVDAIELHSHQLISSKKPMGYNAKPIYTLRQDRLLNADQSWRNQMSRRVVEDWIEVCSGALETTFTVEEADKKGTKFYEFPTGYQAIFKGSERLHPAEIFFNSSALNRIRSYGPPPIAENHPSQGRMIPLQEALPLQNLIAHALDLQDIDVRSSLMQNVVLVGGGSMLPGFQERLLFEVSNLTRNKNYKFHIPTVPWERRFSSFLGGSILASLGTFHQLWVSREEWNEFGPDILAQRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQK7</accession>
    <name>M5FQK7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_25440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623932.1">
        <property type="nucleotide sequence ID" value="XM_040774163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQK7"/>
    <dbReference type="STRING" id="1858805.M5FQK7"/>
    <dbReference type="GeneID" id="63689225"/>
    <dbReference type="HOGENOM" id="CLU_079937_2_0_1"/>
    <dbReference type="OMA" id="CAIPCFV"/>
    <dbReference type="OrthoDB" id="4505683at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067064" description="CFEM domain-containing protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="8">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="15863" checksum="33993F0F041D26BB" modified="2013-05-29" version="1">MQIALVFLTLLAAVAAQNTTSSAAGSAPTGGIPACVLACSQQASTVANCSFLDTSCSCLNQQFQAAANNCLGANCSASDIAAGLALQNATCSGVAGSLPVSGSVNGSSASSSGSGSGSGSSTAGGSTSSPATSSPAATHSSAAGMAKPVSVTGLVSAIVAVVGMGIGAVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQP2</accession>
    <name>M5FQP2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA/RNA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_111386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624766.1">
        <property type="nucleotide sequence ID" value="XM_040769223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQP2"/>
    <dbReference type="STRING" id="1858805.M5FQP2"/>
    <dbReference type="GeneID" id="63684285"/>
    <dbReference type="HOGENOM" id="CLU_421513_0_0_1"/>
    <dbReference type="OMA" id="MFKRQDE"/>
    <dbReference type="OrthoDB" id="1747274at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46404">
        <property type="entry name" value="DNA POLYMERASE IOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46404:SF1">
        <property type="entry name" value="DNA POLYMERASE IOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="2">
        <location>
            <begin position="8"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="650" mass="72388" checksum="82B23DBCFF64CB93" modified="2013-05-29" version="1">MEPEARIVLAFDLDNMYVACERLRNPSLVGKPVGVQQKGLLATASYEARALGVDKLCSLWEAKKRCPSLILVNGEDLTLYRYYSRRVFLLVRSVLGDCPVEKLGMDELFCDVTNLVKEHLQETRDISPDPRGRWFALARAESGALTDYKGFWYNPSSECPGHTIPQYDPTVSDNATLPESILAASHLANHIRHLVLTQIGLGSSAGIAYDKTIAKLVGNMHKPHQQTTLVVSPTASEEYSTVVQTLLDPLNPHKLMGFGSKALHTLRDYISTTKYPITSPSTKEDDRDELALTVGLLRSKMTAALFGSLLGAQNGQKIWDLLEGRDNEPVKMSPEFPLTISVEDSFDQQRGTLDWSGVLTEIETLANSLLRRLEIELVDGGELETLGREAVKPDRRRKWQRYPSQIRLTIRGGHSRQIAYNANRESRSAPLPVPVFDLDIPRTERAQGLIRQPLAGLAKQILDKGGEPVEKYEFSIINIAVTNLQTTTPTKAINAFFAASPWDKQENKRIRHSHEAKEPASSNGSKRRRRTLPPDIDINMIKELPADIRDEVVREYGIIEFEEPPSKIIKRDVTEHTLELADDVNQASATPESNTVADGKKLSSVLESMSDDGCWTSDDDDKKAMTPCTLCGAVIFDWSMAAHMTYHSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQY9</accession>
    <name>M5FQY9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_59472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624112.1">
        <property type="nucleotide sequence ID" value="XM_040775563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQY9"/>
    <dbReference type="STRING" id="1858805.M5FQY9"/>
    <dbReference type="GeneID" id="63690625"/>
    <dbReference type="HOGENOM" id="CLU_107661_1_0_1"/>
    <dbReference type="OrthoDB" id="2555434at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="25492" checksum="137553C9B57E5713" modified="2013-05-29" version="1">MPVPSSSPRLQTHQSHPRHTYNAHRASSFLVTDPREEDEIRARLRTFEGAYSRTAMATLGYSVLILKLFNREFYRIGLLYVILSLLLLLVEFQRRRHARHQFADEDTTPPPPGSRQHPENPQSCPQQRRDAGETSHSVSVRLRILSGLPESSVAFSSLPEPTRPITSNYPPIRRLSLRSGSRLNERRERVWGGREFKTPGWIVVLVTGIVGIVEVTLFAFVCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR05</accession>
    <name>M5FR05_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane fusion protein PRM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_84813</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624152.1">
        <property type="nucleotide sequence ID" value="XM_040776702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR05"/>
    <dbReference type="STRING" id="1858805.M5FR05"/>
    <dbReference type="GeneID" id="63691764"/>
    <dbReference type="HOGENOM" id="CLU_010191_2_0_1"/>
    <dbReference type="OMA" id="NVFGWVN"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032220">
        <property type="term" value="P:plasma membrane fusion involved in cytogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026777">
        <property type="entry name" value="PRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31030">
        <property type="entry name" value="PLASMA MEMBRANE FUSION PROTEIN PRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31030:SF1">
        <property type="entry name" value="PLASMA MEMBRANE FUSION PROTEIN PRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0184">Conjugation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="608"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="697"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="773"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="791" mass="86035" checksum="915CA8D4351A8657" modified="2013-05-29" version="1">MPDRFRAPVDPATVDTPLPPYLRLVDHYSLTWLATPVVSLIFVVIKLVLSSYDVQDAVTAMKADVLASCQAAESAATVAASLPRYMAQGTNKGIVDAVNGTIDGAKDVLILTLQALEALIDFIVDMYRSTFLCFLELVIRGGLAVLIGAVQEVTSFLNTTLSAIGTNIANDVSAAQSAVNSAFSVINEGLSFLPGSPQIPQISLPSLAELGNVTIPTDFENSLISLSNSLPTLSTLKDMLTELIDTPFQDVIQDINNTFNGLSFNENVLAVPAQQTVTFCNATSLDSSIDDLGKIMAKIPIIAIGIALLAIVLIIVANCAWQWYRWRVLMKRVRTMKERWNADAAISGMSQDPFANERSTLTFMAESHHMMILQWLEVTLLKRMFKTPTARNNIRWFLAYITYPPALICLVIGLAGILSVELQLALIALFTGDAKNQVSTAVDGLTDAISTSINAAIASQTGSYVNATNSHILGIQQTIDGGVFGWLNTTTVSLNSTIETFYSDVVSAVNTVFGNTILGPPIQEFVACFLGGKVEHIEEALTWIHQNVQVKLPLMPEDILQLSNSSQTEISTNIRNAAVGDPNVNGGSQGLADQLIAKYTNTLYTERWMFGIFIALWVIVVLVAVCTLVWHNWGKHAVYRWKKARWEKRRALLGDVEPPQKEPMADFGASEKGKDIGPDGSLPVIVTPEPASLKNIPHPPSPMPSPGLPPFPPPRTNTRGSPIINVRPFSPPTVSPSGRVMSPELPAYSSRAVPRQLTPSVPVPEENPFLTPFDDRVEDRYPRPSFKPHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR07</accession>
    <name>M5FR07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4336 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626363.1">
        <property type="nucleotide sequence ID" value="XM_040769022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR07"/>
    <dbReference type="GeneID" id="63684084"/>
    <dbReference type="HOGENOM" id="CLU_056292_1_0_1"/>
    <dbReference type="OMA" id="IFRDVMA"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26423" checksum="76B4115B4C9F4FE9" modified="2013-05-29" version="1">MSDEIVIREVVPGLTIFSKPFARLGIVPFGGRTTAIKLNSGEVWVFVSTPLSDDTKSTLDSMGIVKYLVTPDALHTLYISEYHKAYPNAKCIGVEPLIHKKKDINWAGAYGFAEGTTYGYEDELRACYFSGFQNKDVAFLHIPSKTLIVADLLFNLPGKEQYSKSKQSGHSIFTSGLNPYSGFYKRFLNSVTSDKAAMGRDAKTVASWDFERIIPCHGDVIEGKGKEAWTRAYANLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRA5</accession>
    <name>M5FRA5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626528.1">
        <property type="nucleotide sequence ID" value="XM_040771271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRA5"/>
    <dbReference type="GeneID" id="63686333"/>
    <dbReference type="HOGENOM" id="CLU_2170985_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067171" evidence="1">
        <location>
            <begin position="30"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="110" mass="11700" checksum="574FAE05BEFD7FDE" modified="2013-05-29" version="1">METRPLCTPIALIALAVVLLLLLSSGTAAMPIPAPALPRARRRPAMSDKAMFALKNIEITRTSDPARIRCLPVTTPPTFSTEAGLVMTCIMGACPPDVEGANRSLPDRDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRQ1</accession>
    <name>M5FRQ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625316.1">
        <property type="nucleotide sequence ID" value="XM_040769136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRQ1"/>
    <dbReference type="GeneID" id="63684198"/>
    <dbReference type="HOGENOM" id="CLU_148790_0_0_1"/>
    <dbReference type="OrthoDB" id="3257409at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="13162" checksum="0A8CA364F6B47741" modified="2013-05-29" version="1">MSLPAEEPRLGQEEPELELEPELQQQQQEEEEQEWQMHDGEREGEGETSGIEELDKEIDLESRMIPDNLLAEDEKIFTTFYTKMNGHFTNAQYNTLNFTYPNIFYNLPYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRW8</accession>
    <name>M5FRW8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease</fullName>
            <ecNumber evidence="10">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_110954</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="10"/>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625406.1">
        <property type="nucleotide sequence ID" value="XM_040769151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRW8"/>
    <dbReference type="STRING" id="1858805.M5FRW8"/>
    <dbReference type="GeneID" id="63684213"/>
    <dbReference type="HOGENOM" id="CLU_055174_0_2_1"/>
    <dbReference type="OMA" id="YVMPNQV"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000008">
        <property type="entry name" value="Probable NUC1-dna/rna non-specific nuclease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067108" description="Endonuclease" evidence="12">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="14">
        <location>
            <begin position="80"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="13">
        <location>
            <begin position="81"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT98508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="348" mass="38080" checksum="3564C8D1D6489F8D" modified="2013-05-29" version="1">MPSSTILHLAAFATGCIAGAGAVWTVTRTKHTRVDVARPSDTYPQPKIAILPKPSTDVVINPPTDVLKYGHPGPISDILQRTAYAARYDRKLRHPAWTAEHLTLASLGKGPTRLGDDSGRGDRGNSQFKEDESLPEMFRAKLSDYFRSGYDRGHMVPAADAKISQAAMDETFLLSNIAPQVGAGFNRHYWAYLEDWCRRLTSSFSDVFVFTVPLYLPHQDPDGKWRVSYEVIGTPANVAVPTHFAKVVLASRPLSPVTPNILELSLGAFVLPNAPIPDNVPLESFSVPVETVERAAGLTLFSTEVKKESKHICRTAKCEVIVRRFDDAQKTVQGGGGKPLRIGPPQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSE0</accession>
    <name>M5FSE0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_23250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627228.1">
        <property type="nucleotide sequence ID" value="XM_040773173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSE0"/>
    <dbReference type="GeneID" id="63688235"/>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OMA" id="IFTTMFM"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="274" mass="30048" checksum="B80647456172E697" modified="2013-05-29" version="1">MSGNQAVNINPPNAQIDITSHGSDWLWAAFSLFTIFDLGMVAWMWLRPKTQRVLHLLPIVILTVTMVTYFTMASNLGSTPITAEFYGNHHQDQAGDPATRAIWYARYIGWTLSLPLLVAEVLLATGLSATEVSAALFMEVVFVVSYLVGALVSSTYKWGYFAIGTAALLYVISYLVGPGLIAAGHVGADVRKVYITTAPFVAFLFFLYPIAWGLSEGGNVIHPDSEMVFYGILDLLVQPVLLFAYIFQLRNIDIARFGFAPRETIIGEKPAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSI6</accession>
    <name>M5FSI6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CBS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_82605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625751.1">
        <property type="nucleotide sequence ID" value="XM_040776577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSI6"/>
    <dbReference type="STRING" id="1858805.M5FSI6"/>
    <dbReference type="GeneID" id="63691639"/>
    <dbReference type="HOGENOM" id="CLU_021740_2_0_1"/>
    <dbReference type="OMA" id="TASIHPF"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="140"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="225"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="299"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="368" mass="41008" checksum="ADD099966DC2E4D9" modified="2013-05-29" version="1">MEPHSPVRRKPSQARRARAASHLPQPQTPETHAAALLAVRKFMKSYTPYDVFPVSFKQIVIDTQLEVKKALQALLQNGNVSAPLWNSEKNQFAGLFTVLDIIHLIQYYYATATSMDSAVSDVEHFRLEAIRDIERAINVPPPPLISVHPLESLYEACRMMLQTHAHRLPLIDKDSQTSDPLVLSVLTQYRVLKFIAANCRDTSHLHMSLRTLGIGAYVQPGVKLDDPHWPLATATMDTTVFDVVHMFSARGISAVPIVDSNGKVINLYETVDVITLVRNGAYQHLDLTISEALSHRSADFPGVITCTGRDSLGALMFLLRQRRVHRLVVVEGEEVEESRRGRLVGIISLSDVLKYLVGPIEGGALQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTE6</accession>
    <name>M5FTE6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795895">
        <property type="protein sequence ID" value="EJT96516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623414.1">
        <property type="nucleotide sequence ID" value="XM_040771439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTE6"/>
    <dbReference type="STRING" id="1858805.M5FTE6"/>
    <dbReference type="GeneID" id="63686501"/>
    <dbReference type="HOGENOM" id="CLU_031807_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="38821" checksum="C1523D10AC7D418D" modified="2013-05-29" version="1" fragment="single">MAVPCLSTGCIEEMVTVSLASDTSPVILQLLECSKELNAEGDTFDPPYFILTLSDGASFITKVVLHSSVVPRLCNEEIKVYDVITLMSYESCILMPIAFPGWANIISDWQAYCHSLGYATAPYEFHYVWPQLPQAAPPPLMTQITMMGVGVVPSEYVALMLPVLPPPPVPIPTQVDHLLPINASLDHTALHIMQGTLPMFRDHSAACASANHTPCVGNNSFHCAHSNGANIPSWDKGTIDILCHDLTGKIDLVVHHPVHAKFASVEVGKVYTIFNLDAIVAVQEYCCSFHTSQLDFHHQQSDIAEVPDDGTIPELHFSICQIIQIPELPDKKCIGLHSIFDCEMCDQNYMAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTL0</accession>
    <name>M5FTL0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Maintenance of telomere capping protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627883.1">
        <property type="nucleotide sequence ID" value="XM_040772964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTL0"/>
    <dbReference type="GeneID" id="63688026"/>
    <dbReference type="HOGENOM" id="CLU_034224_1_0_1"/>
    <dbReference type="OMA" id="RIHLVHD"/>
    <dbReference type="OrthoDB" id="5594977at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018814">
        <property type="entry name" value="DUF5427"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10310">
        <property type="entry name" value="DUF5427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="46069" checksum="10E440CF3DE72747" modified="2013-05-29" version="1">MAASKPTSKAEEALQFLDDLDSFTPAAAPATTGGPTEPTTASTLPPPGEAAEVLAFLDEITQKSSETPKSTASIIAASTSRPPSATPGAAAATPSAANPNRVSPIPSARQQAIEMSAAEASEHHRTPSQTGGWGWGGVGGLWSTASSALQQARSVAEEQAKQLQSNEQAKKWTEGVMGYVKNANLDKLSQDLRTAGISTFNEILNAVAPPIAEHEVIQVWLSHDMHGYEGVESLVYRSLTKIMEQVEGGDLVVNKGNESKPRNTPAYEGERDLNAVEGYEQALKLAQANLEDMIKSHADKPTSSRAVSQHNPTTYSSVFLRIQPYFVDLSLDPGATSDNAPRKRQLQFLLHLSDPTHTLLHTQITQGVPAEWLMIWDDNEWVEDMVVEAIRLGIEVIGQEYVVARMGWMRKGEQPAKPEEETEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU78</accession>
    <name>M5FU78_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623684.1">
        <property type="nucleotide sequence ID" value="XM_040771421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU78"/>
    <dbReference type="GeneID" id="63686483"/>
    <dbReference type="HOGENOM" id="CLU_035509_15_2_1"/>
    <dbReference type="OMA" id="REMIDIR"/>
    <dbReference type="OrthoDB" id="2681239at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="287" mass="31752" checksum="AC15DF7701808561" modified="2013-05-29" version="1">MPSYEQVVQIDQQSTYGLAIGMTLWAYDWMLTLQQETQYVWYSKWTPGKILFLAVRYGGFSTLIVYLYVVAGADVTQSRCTFALYWALCNQVVAIGAASVILALRTYAVWNRNRIAAGVILAAWLAMVGCALRFLVMAIQGVTVDNLDLGLRGCSATNTSTSSTAALRMYITLGAYEGLIFAMTVARGVPLAHKLPKLTVTLYRDGLAVGNAVLTSEDYPTYYLTYFISLACSSVLPARIVLNIREATIDLDEWDVTTAKPVTVQAHVPFQRSRSRMMGDDWGLEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUH0</accession>
    <name>M5FUH0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CENP-B protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_41684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626776.1">
        <property type="nucleotide sequence ID" value="XM_040774506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUH0"/>
    <dbReference type="STRING" id="1858805.M5FUH0"/>
    <dbReference type="GeneID" id="63689568"/>
    <dbReference type="HOGENOM" id="CLU_018294_5_3_1"/>
    <dbReference type="OMA" id="YAHHRES"/>
    <dbReference type="OrthoDB" id="162969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="100" mass="11449" checksum="38A8A30356C8057C" modified="2013-05-29" version="1" fragment="single">LRKITNQYALQDIFNGDETGLFYQMPPNHTLATMACSGRKGDKTHMSYMLTTNADGSERLKPLVISHSKQPHCFQHKTPQSLGFDYHFNKKAWMTGVIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVG3</accession>
    <name>M5FVG3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_23682</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626497.1">
        <property type="nucleotide sequence ID" value="XM_040773344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVG3"/>
    <dbReference type="STRING" id="1858805.M5FVG3"/>
    <dbReference type="GeneID" id="63688406"/>
    <dbReference type="HOGENOM" id="CLU_130038_2_1_1"/>
    <dbReference type="OMA" id="AMVSPII"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000035">
        <property type="entry name" value="Elongin C transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="11949" checksum="561CE1A335D3DBA2" modified="2013-05-29" version="1">MEDNQEEGPSGWVKLISDDGFTFILPEKAAQTSGFFKSTLNSTVGFQESETKVIRCGERAAVLETVVEYLVFKSEFGDSASKTAIPDFMKRIPAALALEILMAADFLDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN4</accession>
    <name>M5FWN4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">methylated diphthine methylhydrolase</fullName>
            <ecNumber evidence="6">3.1.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_66474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42656"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="EC" id="3.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH7 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629255.1">
        <property type="nucleotide sequence ID" value="XM_040775816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN4"/>
    <dbReference type="STRING" id="1858805.M5FWN4"/>
    <dbReference type="GeneID" id="63690878"/>
    <dbReference type="HOGENOM" id="CLU_036100_3_0_1"/>
    <dbReference type="OMA" id="LVCCMYD"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061685">
        <property type="term" value="F:diphthine methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="305" mass="33045" checksum="B6C77D156643A6A1" modified="2013-05-29" version="1">MYRLIEGTPQRRVGGVVLWEVTEDGLNELSTCESAGVLDLHWARRADGTPLLLTANAEGNLNLYTYGLARSSLSSHSSISCSSTALALSLSLPPSPSTPALGETLVSLSSGELAHLIPREEGLELVGVWKAHEHEAWVVAWGAAEQGVLYSGSDDLTLKGWDLRAGTESPTFVTRRFDAGVVSIVPSPWTPHQIAVGTYDSLVRIYDTRAPLRPLESYNVAGGAWRLQFHPSAARKSDLLVAAMHGGAEIVRLSPGAGEDSQERTKFEGHESMCYAARWVTTEGAREDVVASCSFYDHRVCLWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX03</accession>
    <name>M5FX03_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aromatic compound dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_117282</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627122.1">
        <property type="nucleotide sequence ID" value="XM_040770353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX03"/>
    <dbReference type="STRING" id="1858805.M5FX03"/>
    <dbReference type="GeneID" id="63685415"/>
    <dbReference type="HOGENOM" id="CLU_046727_2_0_1"/>
    <dbReference type="OMA" id="RCVMRSD"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="53"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="133"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="334" mass="37051" checksum="C4B4BE6BBB7E462B" modified="2013-05-29" version="1">MSAAQRKAPSKAVQLAIDAGAPTIDPSTLPDVTDISPETVTESVIAINSQCKNERQKFLINNLVRHLHDYARETNLTTEEWMTAIQFLTATGQKCSSIRQEFILLSDVLGVSALVDSINHARPPNATENTVLGPFFTEDANDIDQQGSIASEGKGDPLLVTLRVLDTQGRPVPGARVETWETDAEGFYDTQYEGRTGPDCRGRLKTQEDGVCEFWAVVPVAYPIPSDGPVGSLLRSLHRHVFRPAHLHIMVDADRFETLTTALYLEGDEYIKSDAVFGVKRSLICKIDRVADEAEAKKHAKSTPFNQLKWDFVLASKEEADLVRAEKMEKMRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX49</accession>
    <name>M5FX49_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627901.1">
        <property type="nucleotide sequence ID" value="XM_040772970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX49"/>
    <dbReference type="STRING" id="1858805.M5FX49"/>
    <dbReference type="GeneID" id="63688032"/>
    <dbReference type="HOGENOM" id="CLU_065200_6_2_1"/>
    <dbReference type="OMA" id="SWIAECG"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="22677" checksum="C9F308A4E0C3CCA1" modified="2013-05-29" version="1">MRHKDTSFVKFALFFMSTAFQFYIVIYVISLSTRVGLAFVYPDIESRICTCQPSMGMILAGIFGCLLGWIGTELRAWCYKALGQYFTFHLAVQENQTLVTTGPYTYLRHPSYLGGCLEFLAVSPTLILCNPISMCWGRHLLSRGPQIEAAFMLFFLVAPWIAYPQRIAVEEKMMKAKFGKEYAEWEKKTWRVIPLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXS4</accession>
    <name>M5FXS4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_57316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625224.1">
        <property type="nucleotide sequence ID" value="XM_040775430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXS4"/>
    <dbReference type="STRING" id="1858805.M5FXS4"/>
    <dbReference type="GeneID" id="63690492"/>
    <dbReference type="HOGENOM" id="CLU_002498_5_0_1"/>
    <dbReference type="OMA" id="THEDNQD"/>
    <dbReference type="OrthoDB" id="2692094at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="161" mass="18526" checksum="767B126E353F1CBD" modified="2013-05-29" version="1" fragment="single">IHWHMVCCINYTTYDVRHAQDTIHVGKGQCDIMLLSGEDSMDSHPYWYAQMVCIFHVNLTHQPTNICTPQWHDVLLVRWLAQEDTDSTGSQLFQPLDQVSWVSGDNEDAYGFVDPSSVIHSCHLVPCFHSSPDDVSASEVTLLKRKQADVHMDWKAYYVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY13</accession>
    <name>M5FY13_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627572.1">
        <property type="nucleotide sequence ID" value="XM_040773074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY13"/>
    <dbReference type="GeneID" id="63688136"/>
    <dbReference type="HOGENOM" id="CLU_003703_1_2_1"/>
    <dbReference type="OMA" id="TECAECC"/>
    <dbReference type="OrthoDB" id="3192989at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="1">
        <location>
            <begin position="93"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="185" mass="20684" checksum="8BAB64D966BAEE20" modified="2013-05-29" version="1" fragment="single">MPALGEFSKLEKLFEDELLRREGPFKPGERCRDCLQGSAVSRCTECFGRQGFCDACIAQAHKALPFHRIQKWNGLFFERVTLTKLGAILAFCQCCGSNCNRRKITVVHTNGLHEVEIGLCAGASASPHFIQLLQHDMFPATIKSPVTAVTFDCLRDFHQHSLCSKKSAYDYVTKLARSTDNVVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYA6</accession>
    <name>M5FYA6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_18132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625434.1">
        <property type="nucleotide sequence ID" value="XM_040771335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYA6"/>
    <dbReference type="STRING" id="1858805.M5FYA6"/>
    <dbReference type="GeneID" id="63686397"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OMA" id="IHTAHAN"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="285" mass="31037" checksum="903EE5C7C638FB5F" modified="2013-05-29" version="1">MAPQIWFITGTSTGFGRIMTEHVLKNGGIVVATLRKPEMLADLTRQYDKTRLLVLKLDVTLSSEIPPAFQKAIDAFDRIDVVFNNAGFTLIGESENTPENEARNMFETNYWGAVNISREAIRVFRDINPPGAGERLLQNSSIAGLGPLVLFGHYTASKHALEGFSKTLATELNPSWNIKATILPGHQNYDNETTASLRSALAIGECPGDIDKGVAIIYDVAQLSNPPLHFPLGLDGVKVMRTAGALLAETATQYGQMSEGLLRDTMGEAAHVIKMPSSRIAVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYC7</accession>
    <name>M5FYC7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625454.1">
        <property type="nucleotide sequence ID" value="XM_040773736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYC7"/>
    <dbReference type="STRING" id="1858805.M5FYC7"/>
    <dbReference type="GeneID" id="63688798"/>
    <dbReference type="HOGENOM" id="CLU_622600_0_0_1"/>
    <dbReference type="OMA" id="EYFITHY"/>
    <dbReference type="OrthoDB" id="2535105at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="264"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="440" mass="48914" checksum="F3DCFBCE7DEA91D8" modified="2013-05-29" version="1">MTDETFKWSMKFQCERKRNHSPCKSAPSFLSLLGHSLCLPVKAHKSAYLPYKSARFPFPFLSLDPSSSLFTEALPRPLIVLPSNRPVMSAANPGYAPSPTQMDLTDDLGGLFVGMIISTMLLGMGLAQTWFYYRTFPDDPIFTKWMVGVSCFVNVLHGIMLPKCIWYWVVTNWGNTASLNYVDFSYNVNLTLTGLLSFLVQVFFAHRIYILSHRSLFLPIIILVLSLLQFAFSLASTIRAFQLVLQSSFGVFTWGVDVWMYCAAGADIIIAASVVTYLRREGKAAWGGTKGIVEKLIVITLESNLLTAILSIIVAILFTTTRNGWPNAINFVAVRMYFISLIRTQVTTARHELTKKLESSGVGAPAFHMSPVNIGPRNLGDNLASNMLSGVRIMSHTTTELDEPLPRNAGRRNGINHVELGVASKINETDEVNCEDTDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYF3</accession>
    <name>M5FYF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_16306</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627777.1">
        <property type="nucleotide sequence ID" value="XM_040771185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYF3"/>
    <dbReference type="STRING" id="1858805.M5FYF3"/>
    <dbReference type="GeneID" id="63686247"/>
    <dbReference type="HOGENOM" id="CLU_329825_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="12">
        <location>
            <begin position="604"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="549"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU00880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="870" mass="97517" checksum="9AA1206A468414E9" modified="2013-05-29" version="1">MDTTSLLILATPSIIVLLFLYITLQYLTIKEVVSLHELPGPPGGWYGPVGHLPQLLDPDVSPETHERYTRLYGPTFQTFGFGPLDRRLFSLSPPVVKYILDHPEKYQKGWQGRAYVDQAIGEGGLAMAEGTIHRVMRRLLQPVFRKKNLDALSPISSTKALELCHMLHAHSLSRPSAELDILPLLTRATFDVIGLAGFGHAFDCLSDPGRDPLYQAFQGLFSSISGFTLRMWMGIYFPWLDERFPDQRVKTIRESRALIDSTVKHWIRDRQAEIGGEKPNTPTVQEIISAAPKAPMVDELVIAQVNTFLMAGSETTALTIAWALYYLSQNAAVQFSLREECMSVNPDMPGAFVDGVDRLPLLEKVVRETLRLTPAVHSTFRQAMEDDIIPLPPTPSKGGETAGRRQGPIGISIRKGQYVRIPLEGLNTLQEVWGEDAHEWNPARWDALMFPPSGEKLREDGKGRTGWKTWAGLMSFSAGPKACIGMRFALIDLREWAKEMTGSRYSCSIWCGSLKSRVRNRSSSGMLCTVETLELCKCTAYPHGECHSRTASYTRPTSSPPTPTTYTFIHPPVPRSPPAPRTSAPLPKAKAPFSKHPAFDNPDADLILRTGDKVLFRVFRVILIESSDIFRDLFAIPHPPTPPITPSSSSSAHPMIPVLDIPEPARLLNDFLLCIYPLPHPRYTTLEELMPMFDLARKYTSQRVVDVLRGQLVNPDLMRKTVPLRVYALACKEDLEQEKRIAAAACLDIDIDKAALYMEALWPEELKDWSALDLTRLIRLRDTRFELAAELVRGLEGKGVCCVGSCRHDFQADYFPEFQEAALMELRKCPTSKVVFTEYLATSGMILAHLKRRLDMLPDNVLEISRNADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYX2</accession>
    <name>M5FYX2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_22883</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627997.1">
        <property type="nucleotide sequence ID" value="XM_040772997.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FYX2"/>
    <dbReference type="GeneID" id="63688059"/>
    <dbReference type="HOGENOM" id="CLU_000772_3_0_1"/>
    <dbReference type="OMA" id="GCQHNEK"/>
    <dbReference type="OrthoDB" id="17907at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016504">
        <property type="term" value="F:peptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="10">
        <location>
            <begin position="400"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="11">
        <location>
            <begin position="1420"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="9">
        <location>
            <begin position="1871"/>
            <end position="1957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1957" mass="223090" checksum="E31973B98D1C92AE" modified="2013-05-29" version="1">MSLPRKRTWEEKWAHDSALLPYPREPNEVMQERLDLYLRRLAQATLAKDYDPGVLQADAMIVYWMSLKYELPKEKRVAMCKLYYELIVQPGIPYPLVSMSVDRLGTLMRSKNDITIDDIRLPWKPIYAYLKKNTFLNRRQFELNSMPLQFGNLAETCKRFFHPIETDEMLDTFLPGIIGAHLDTLLEAQYYMSAFLPLTHPTSWMPMIFKLWEAFNSSVWDARSFQMLSQVAELHVDPTVSDPKRVREIPDDAREGRKQRIVWEKDPVPKGAWKGLFKDVGIFDEEQWNFMMIKCLATMSIPLADTGSLATGTSTDTQASFEIGRLPPPVWEIHSLARIIVYSMSRDGPASASSGFSTPEILTPGPSGHKTNGLLRDLFKPHHEKVKTYLAGSKALDSFARLIVSTESFFHPSNSGSWTGNLCALVRHVVNQFSKRWAEEQDPECKTPLFRRLTTDMRRELVVTVKTVVLLAMFSKDPTIFDHVMSTIKCICSMEPEIMIEPILERAADALETLVETDRTTAVISALSACGPALVSRTIFPAGAKHLLTILELCVPGIDLNDPTKTQLTTSFLLEVLQHIKIGDLTVPEMPMENGAGESDDEMQTVRSPTIPKVSLETIADGGDPMSPIVEVAGESDEDKLLRESTSRFSTWLSSFFGRVFLMMDNLPEDPEGASEDPLLETVFAVCNQICTHLSEPLFDFVLNLVFDYVTQNVRPNAAGSINSLIACVANGNPPKSMAQFLPHCERVIRSELENGASSIRSTQWGQQRSSDATFHWNLGLLRGLMDGNGKSLLPYKENLLSLLRLLRDKTYSKHGYTWTGELLSDLLLALSHTYPQNTWFVNRETWESADFKLNHHRYWGKNYAPQDVKVEWHVPNEGEVALCMQILQELVQPTLATLKSLFDESVERDAVWRNDVCRLFCFVRNGFTGIQTLWKEHVSMEEAIAVSAIGDVLDEIPEFITHGSPIESGFPLSDEQDPRWQYIANLKEDFGNFVHRASMFLRQHGDENAVDPVAMIVLSIATFFLEYGEAAEDYKTVQEKYNNEKRIARLVPVQKLWPRMVWVRRARLLHAGRLRWNSLDRRQSKLERDLVMDVLEWSLWSFPTIRAAAQNTLSLICVGFDGVRNQCFPTLYHALQPGIDADRMKGALYTLNLPNFARYACSEPQKTPEFVEALFGCQHQEKPSIQSCVAALADNAIGTIAEPNNLIYLLETPGPDNAAKQLLRVVLPEVESDVLIKKCLENRIMRMQKIEKAIQDTVDILLRVATSPNTHWKYSILAIRFLRTLTRRDQPANAVWTEWLFKAVINPNPRVRYYAQRSIQKTLRFIKFRTFCPTPYDLTISRSQNPYKKIIHPKKTNEYTAQYLQAFKTPIREDDIPYIEVQDKASSGWIAWRNDDTRYVFPQRSRHISEWEEASRPAVKAVSAAVLDEAFWRQYAAYLSEETQAESTSPDAIFCIKSIFQLIGDAPLATMRPVLDELLVADDMNKQRAAAEFLAGVITGSKHWALDSQKALWDWLRVQLPTTFKSIKTDTLGIWCSFITTIATNRDPRRQQPLVDYIVANGLEVDFNDQSSFEVVKKESFVRAIDADLGWRFSAWADNFFDRYWEEVGSQHEEVRTYISEAFTLYVKLKWRPRVSVPTAEAFVRECRDPSPQRDVMGLQSGYKLDEFLQLIAQLPKWREERLHGAMAPYSTYDKVAGTLVRFLFGMLHDINAAMAFQYILPMIPELFRMLIMEDSTDLAARSAMLLIRMNGVPMPRNTLSSVLSTLFDVIRTSTSWKVRLYAIPGLQVLYFRQLPSLSDETVEDILSVLEESLMDEVVEVRQAASDTLSGILRCSSRHSVISFKDRFVFRAEATPIPPRSDPNFAIAVRTVHSAILGISALLGAYPYTVPSWCPELMIFLEKHAYDPIPISTTITETARMFRKTHIDTWREDKDKFNEDQLSALSTLITGSSYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZB5</accession>
    <name>M5FZB5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHF complex subunit HOOK-interacting protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_59996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FHIP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623745.1">
        <property type="nucleotide sequence ID" value="XM_040775602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZB5"/>
    <dbReference type="GeneID" id="63690664"/>
    <dbReference type="HOGENOM" id="CLU_004953_0_0_1"/>
    <dbReference type="OMA" id="DHAQEFH"/>
    <dbReference type="OrthoDB" id="5350595at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045669">
        <property type="entry name" value="FHIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19314">
        <property type="entry name" value="DUF5917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHF complex subunit HOOK-interacting protein C-terminal" evidence="3">
        <location>
            <begin position="731"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="820"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="877"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="917"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="881"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="958"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1009" mass="112261" checksum="C2DC2D9AD9242AF0" modified="2013-05-29" version="1">MSYFTKVFRSTPKAEQKDSNADVASFTHSWEHIRDTLQRPDERQLTRGIGFTDIPNELRQLVNQLVLESTPDADTTGPCLEYTLKHDVLNTLVRLSSNDLPFGIKTEVVRAMLNLVVLMDEHFLVHSTVHKAVLRLLRSCVRDESRSFDGGTKARGAAGASRGRPSDYEEDLVDLMCALCSRIRLYPQLLLIFFHDKNVYHDLEEDEIVQADVNDEDDAAELSFASITSTALEIAQRSISPTPSATTITSAPTASSFYRRPEYEFLAYNYLLRFIHREGKIGDNARTGLLFLMDVAMSASELSPHKPGASPPTSDPLSEASLTFAEYILESDFPDVLAAALGAVYSLLPSKLIVRKEGSRGKEPNGTMVLGGMKSNEDESDIDEELERARAFGMDVSTSPEFKARLVHFIKMIDFIQEVVIRETTPSDNLDNSASTTIGRSIAKSILKFLRSSFLENVLYPSILECSDEDGSAVAVITYLEAILSTVKDDQMSEVIINFLTSDDGEEPAKEPSHLKKQKNRSRKSKQKSRQSTALTLLQLETGNRRKSTYYNSLGRFTVKDLLLSNLESKSQPTASAALKLLNTLLTQHGLLALPRIFTLLPETNLYLNGHALDEDELKTPRPGFLSPEDDFFSTAYSPRANASKSEDDLMALRHVPLEIDDADSWRHLVARIDPKFAAEAQRGGNTQYLQDAQDWLETQLLWSNPLLDSEADTEQILSLPDRKYRLSPTDPLLAQLLNVTQRFFSHSPDMNLSLTGVIHAIACSPQLSLADWITHSVTSHGSTQPAMYTCLSSLTAQLPKYRHQAPKFDQYLEQRRRGLLSSAQQDSDTLDTPVKHPTSSSQSAPVSEHSGPVTPAKKPHRYAGFVAYFSPSRARAASAEAEHTPPHSRHDSRESPPSPLERHYRETRAVHLTPLKGALPSAGPWSPAQRKRQQVTSPDERDEPEGGAAAWGGEDEPVSRPKTPEQREEKEVETTTLSELLDNVVVLEEGLKEISAVVQMRRVIGIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZD2</accession>
    <name>M5FZD2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628117.1">
        <property type="nucleotide sequence ID" value="XM_040768676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZD2"/>
    <dbReference type="GeneID" id="63683738"/>
    <dbReference type="HOGENOM" id="CLU_1133558_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="26798" checksum="0B0E11323F679542" modified="2013-05-29" version="1">MDLDRAVEGFKARDGFSPHLAASPTAVSSASDVGHDAIGTSKFNMPKRKAVSPLAEEPQSKRSTAGKSTITSPSSHAAAEPSSETSLAVDISPTLVREHISGDVVGIVGRLDRMFDRANQDWKSFAAEAPKVVAEQLRYSGSWHAFSMEFHEVDEYVETVVIEALSAPALNGDTDHDWDAEDADAMVRMFATAARGAELLDKLRRVCAFHVQFRRNESDLLDTALQYLSYNFFTSTLLYTLPVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZJ4</accession>
    <name>M5FZJ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">(2E,6E)-farnesyl diphosphate synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Dimethylallyltranstransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Farnesyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Farnesyltranstransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Geranylgeranyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Geranyltranstransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_72666</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623820.1">
        <property type="nucleotide sequence ID" value="XM_040775976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZJ4"/>
    <dbReference type="STRING" id="1858805.M5FZJ4"/>
    <dbReference type="GeneID" id="63691038"/>
    <dbReference type="HOGENOM" id="CLU_014015_6_0_1"/>
    <dbReference type="OMA" id="CAFLEML"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF44">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT96922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="355" mass="40317" checksum="AE1C3DB1A81B468C" modified="2013-05-29" version="1">MSRYGGAPGWEDAALDRALMEPFTYTTSHPGKDIRRTMIAAFNRWLHVPAEKLDVISRVVNMLHNASLMMDDVEDDSALRRGFPVTHKIYGIPQTINTANYIYFLAYQELFALRQGHAASAHKDVLPEVQAQDVSDSEGEEEQKQGQLAQTQLHAVQEPQSQPQPQTRSLGLDELVTEELINLHRGQGLDLFWRDSLICPTEEEYVNMVLNKTGGLFRLAVKLMMACSESNVDYVPLVNLISVLFQIRDDYANLELKEYSSNKGFAEDLTEGKFSFIVVHSVRADTTNRVILNVLQKRPTTPSTKKYAIEYMRDHTHSFEYAVEVLRSLDAQARREIERLGGNKELEGILDMLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX0</accession>
    <name>M5FZX0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626004.1">
        <property type="nucleotide sequence ID" value="XM_040769050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX0"/>
    <dbReference type="GeneID" id="63684112"/>
    <dbReference type="HOGENOM" id="CLU_1326340_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="207" mass="22429" checksum="147ACBAA012C19D6" modified="2013-05-29" version="1">MVSLDNAGEGLGEMLVSAKMKEMVLTDMVEGEGWKGKGKAPLQSEMPVTLRHKLLLTVQAASSLNNNTSTHTTLEDSEPPSLTSIYSQDIPVCLGPTKHKQALAEAPPCLPGNEEGYEDHISALTYSLLNVTKNCALKGDLPGILKMIELIHLDFEHKALARTSSSTSPPIIDEERIICPPDPNQGPVLLLGQHRLTKSAHLRVPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZZ7</accession>
    <name>M5FZZ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
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                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
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                <person name="Kuo A."/>
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                <person name="Sabat G."/>
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                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
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                <person name="Martinez A.T."/>
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                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
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                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
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                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
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            <strain evidence="2 3">DJM-731 SS1</strain>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
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            <strain evidence="3 4">DJM-731 SS1</strain>
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        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="167"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="401" mass="44841" checksum="62D30ABC4BB2F32C" modified="2013-05-29" version="1">MNGQRLAAGVRGTLNAPRQAQIVPRCIARPACNYSSSSLLISSLNDLNSPRLARHHPPRIPRARVVRSQSTDASSHRAPSSPFPSPYDEQSPPPATNYVLDDYVSRSLNANPGATARRHRTRSDRPPVAHADPFHKRSLHPIAPCTNAEVVEYFRQLLDPLEFSEQFAARLVTHTSWGGGMEGHNGRFIFLGRRFLRANMFMFLQSAEVHAPESKFVVPPWSEEIEAASQKMLETHILGRDIGSAWELERVMRWVPIMPDSTDRERIFVSSGLYKVRGATVEAVMGGILHQYGGLVAHRAFQTRIVPHLWQHLPLSYQRTAEELAERMGGPKAMLLIPPVTPSVSSGEPIEPQVEKEEKQRPPLFPDDARTVKEARGEMQRSKPAEAVKPAPSHNKMLLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0E3</accession>
    <name>M5G0E3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SMG7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_89295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628507.1">
        <property type="nucleotide sequence ID" value="XM_040776905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0E3"/>
    <dbReference type="STRING" id="1858805.M5G0E3"/>
    <dbReference type="GeneID" id="63691967"/>
    <dbReference type="HOGENOM" id="CLU_011778_1_0_1"/>
    <dbReference type="OMA" id="WIQLIVR"/>
    <dbReference type="OrthoDB" id="69928at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019458">
        <property type="entry name" value="Est1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF36">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10374">
        <property type="entry name" value="EST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomerase activating protein Est1-like N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="1">
        <location>
            <begin position="232"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="83031" checksum="627E4A67E4129D6C" modified="2013-05-29" version="1">MALPADSDPSTVLREAKGLALDLKKSLKSTPPWDRAVELQRQRLRDHYVQLIFQDLRADMAQQHLWSETSHAIIDVYRARIQQIESAIGADRAELRGNLRRSAHGPVELRKVSQSFRTFLLQEEKFWRQFSLRLVSSYGLMEVLSILAQVGISEEPVLDDDVNQPDLNSSRAMVTDEKRIDKIDMLQRSIIYLGDLSRYRDLNEAQSNSKRTKGRNGIDSMERKISRDFTTSEAYYQAAIVLAPNNGTPFNQLAILATYQSNSFDALYYYYRAACTTQPFGTVSENLERLLSKAIQTYRRAQTDEESRPPMEDHTNAVDALKQDVVILHGLWARNSRSTSAKLCHSIENRFHSLIVERTLPPEVLVRLLLMDFAVLWRTENSKVSTREPSDGGAPVESSSSTWPILCHILDLISDLFTIAQDEVSQADVQASPVLRISAILRRVLPALRLASKWMCSRFASSEWDQPPSSDLAARLTIFWASYVAFLNVMSCSFPLSDLPKPNQILEEDFTPIGFLPMLARDAVPHISAPAAAAKYHPNEEHLIRIADLLWDGITLAQAEATPLTPSDLLFGSNDPSAKWTPKLDEKPKRTGVAYVAGQADPVVLSEKDDDVSTTTSDDPVNMAMRVGLGLSSLTDAEEEEEDVVLFPRAPVENHAVELSGPTAQDLLLQVLGLPEPATPKGTPRAVTAGVAVSVKSSPRVSQPAILFGPNIWSGPGFAPQQGVQQSAISLYGPYRSGPGGVDQTFGGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Y9</accession>
    <name>M5G0Y9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_69191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626389.1">
        <property type="nucleotide sequence ID" value="XM_040775896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Y9"/>
    <dbReference type="GeneID" id="63690958"/>
    <dbReference type="HOGENOM" id="CLU_005027_3_2_1"/>
    <dbReference type="OMA" id="RIDSYTI"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF118">
        <property type="entry name" value="BETA-1,2-XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="1">
        <location>
            <begin position="288"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="603" mass="69214" checksum="8AC566060D3A65BE" modified="2013-05-29" version="1">MRLLEAAALPTEEAMVVQVPDQAPLEHPLPPPRIMQAPAIKVELQGHTYLANGLLQVNPRGRHPIYDLITRSEREWEAKLARQSRTLPDALNEYKRRYGRAPPMGFDRWWAYVQRHGVQLPDEYDQIMRDLESFWGMAPRDVRRMQSLARGKEGTYNIASSSVKGKIELSGTNLGKGEEEKRGAERAKEQLDLLHGFGETWTDERTGQATSVEREIVKATGDWEATFNLYDVPREFVSYEWDSERRMKAQSAAVIEGPQKAPGQTNLGWAAACPPNSHLRYSYPPPPELPIQFLERKTFIHSHRLTMNPCSHSSLVHLSGVLLAEGRGPEVQEPALIFGSSTMEGLYADILTVPTQGWVAEAEGDVEWEEKLDERLLWRGSTTGVLFSPEHRWAASQRIRFMEMVGVHDNFLNYSVLLPNPEDTPVGIPEPRFQSWMNALLTDAAFVRGPVQCTPSECDALWQLYEFRSYMPHTQQYKYKYLFDVDGNGRSVRFERLMRSRSLVLKASIFPEWYSNRIQPWVHYVPVQLDLSDLYDILTFFRGDVGRGGEGAHDELARKIAYSGKAWAEAFWRKEDMVAYVWRLMLEYSRVGNDAREYLDFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G134</accession>
    <name>M5G134_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HD-domain/PDEase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_116132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629343.1">
        <property type="nucleotide sequence ID" value="XM_040770144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G134"/>
    <dbReference type="STRING" id="1858805.M5G134"/>
    <dbReference type="GeneID" id="63685206"/>
    <dbReference type="HOGENOM" id="CLU_013818_1_0_1"/>
    <dbReference type="OMA" id="HYTSREM"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="4">
        <location>
            <begin position="66"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="463" mass="52383" checksum="979F6DB8E7969920" modified="2013-05-29" version="1">MEVYKWALGAQVQTFPMVSRKLSHMAAAPVDGWSYGGWGQPIANGEYEFRTLLPAVFARTEYPFIRSISLPPEPDLETRSRLIDLMCQWSFTSLNLSPIEVYHCSCLIFESVLTLPELKKLNIVDDIRRFLHTLRFLYPTNPYHNFAHAVDVLQAVYAFLEPEVVPPLAMMKRVDPTPLSPHPLPTLPFGSPWKPVPLLLGDSYFRLRPLEILAFLLATVGHDVGHPGLTAQCLANACAPIATLVYQSPLESLHYTLLAQTLRTHGLGMVLSDRDTEELMRNVIMATDMQLHAHHMRRFATELSPSKLASNSREGYLQRVLLCQAVLHAADISNPVRVFPSGVQWSCALISEWSNQARFESSHNLPATQGAWPSDMRTLEYQLKQAKGQVQFLDFATLPLFRVLEGILPKMRAFVQIGLDNREVWENRVERLSSLHHDPRDRVPRSLVPGERFPYPDGDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1I2</accession>
    <name>M5G1I2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_107017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628967.1">
        <property type="nucleotide sequence ID" value="XM_040768376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1I2"/>
    <dbReference type="STRING" id="1858805.M5G1I2"/>
    <dbReference type="GeneID" id="63683438"/>
    <dbReference type="HOGENOM" id="CLU_000384_6_4_1"/>
    <dbReference type="OMA" id="WERAEDS"/>
    <dbReference type="OrthoDB" id="2630497at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="90"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="181" mass="21575" checksum="1AE6A19694BC073B" modified="2013-05-29" version="1">MQEGDKVWLDLRNIQTTWPTKKLDDKWFGPFEIKLQVNLNAYRLKLLKHFLVHPVFHVSKLQRYFPNDIKGQTVMKPPPPIIHKDTLRSFEVEQIEDSKFQYAKLYYRVKWKGYPSSESTWEPKDNLCGAAWPIREFHQQYPEAPQQLSATDFAQLLFHPLENFTKLPKQVLFNWTEGRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1K2</accession>
    <name>M5G1K2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_59015</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624530.1">
        <property type="nucleotide sequence ID" value="XM_040775533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1K2"/>
    <dbReference type="STRING" id="1858805.M5G1K2"/>
    <dbReference type="GeneID" id="63690595"/>
    <dbReference type="HOGENOM" id="CLU_003818_2_1_1"/>
    <dbReference type="OMA" id="LPEVWDM"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00538">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="680"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="796" mass="89242" checksum="EC93074561D366D4" modified="2013-05-29" version="1">MGAVRRDQVRDLWYHGFDAYMNNAFPFDELQPLTCHGRGPDWHDPTNIAINDVNGNFSVTLIDSLSALVVLGDRARFSESVHNVLQYVPTFDIDARPQVFETTIRVLGGLLSAHIFAISEDYGMRVDLYKGELLELAEDLGKRLLQAFNTPTGMPYARVNLRHGVPAGETSESCSAGVASLVLEFATLSRLTDKPIYEKVARRAFYSIWNRRSDLNLVGNSINVISGVWVSPLMSGIGAGIDSFYEYALKSYILLGEPDFLDVWHESYAAVMKHIRGREGFWFRNTWMDSGLLASVYVDSLSAFWPGLQVLGGDIQNAIKSHLVYWNLWRRYSAMPERFNIINKEIEIKGYPLRPEFVESTYFLYRATKDPFYLDVGARVLSDLQRRTSVKCGIACLQNVETGQLSDRMESFVLSETLKYLYLLFDESHPFHVKNTPFVFTTEGHPLILPEQKVRSPAGRRHQRQAEKLSCPVYLPPLVGIREDDHWSPGIVGSVRDRVDVEIARHLVGGPETGQEWWDAEGWCELTQVEEYAFDFILSTDGKPYPEDMSPGPKKLKKVKDGFIINDLTGIRAHIVRRLDDRGYDMTKLGPHRVLTGQKVYINDSRILRNPAPVPADTAKLSLIWHPADPELSRAQWTADGWTASFGPLPVRFPEPARLVIPASPPSGFGCVPLPEIADPVPPLIWLVQRGECNFLDKLSSAKASGARGVIVLSSEVERITPSLGQGEAWEWQEGDTWLIILGRSASAGILERLAKSGQGGQMWVNVDVESREEGAGEGKYLFVDGKPLVNTVLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1L2</accession>
    <name>M5G1L2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Carbamoyl phosphate synthase arginine-specific small chain</fullName>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Arginine-specific carbamoyl phosphate synthetase, glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_76433</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631000.1">
        <property type="nucleotide sequence ID" value="XM_040776201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1L2"/>
    <dbReference type="STRING" id="1858805.M5G1L2"/>
    <dbReference type="GeneID" id="63691263"/>
    <dbReference type="HOGENOM" id="CLU_035901_1_0_1"/>
    <dbReference type="OMA" id="CFSVQYH"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000016">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000003">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF7">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="15">
        <location>
            <begin position="23"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU04106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="430" mass="46568" checksum="3EB2B32ED1956F4C" modified="2013-05-29" version="1">MINFRVQVPKFARGIVTPAAKTVPAALHLKTGQTFKGRSFGAERSVWGETVFSTSITSYTESMTDPSYMYQILVFTTPLIGNYGVPKNDAATDNWDVGVVLESKGIQCAGVVVADVAERYSHHAAVESIGDWCKRSGIPGITDVDTRAITTLLRDQGTTLGRLAIGQDALLLPPAAEEYWDPSFDNLVAEASTSDSYVLNPDGDVNIAVLDFGAKANILRSLVRRGARVTVYPWNFDFNTVRDQFDGMFLTNGPGDPKHAKAAIANVRQTLKEWDRPVFGICMGHQIIGLAAGLDAYRMTFGNRGHNQPVLALADSGSIRAGRVYVTSQNHQYALTLQDPFPKGWEPFFINCNDSSVEGIKSTAESGKKVWGVQFHPESAGGPLDTIEMFTDFVQECRADKEARKGGQVGLGDAVANAGLFAVMGGLFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1N2</accession>
    <name>M5G1N2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_55550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626664.1">
        <property type="nucleotide sequence ID" value="XM_040775333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1N2"/>
    <dbReference type="STRING" id="1858805.M5G1N2"/>
    <dbReference type="GeneID" id="63690395"/>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OMA" id="DFDKRHM"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF19">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01812)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="78"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT99766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="541" mass="60091" checksum="E63A99D86B607EFE" modified="2013-05-29" version="1">MDSDGKPTSALVEDINGSSPTTSLAEKSHTHPLPPPHLHAPPSASFAARLEETPAQLLTELPAYEIERQLLRKLDWYLVPWLSLLYLLSFLDRTSIGNAKLYNLEKDLGITDHQYLIALTIFFISYAVFEAPSNVFLKRLRPSIWLSFTMLMWGIMMTVQGLVHDYGGLLTMRWFLGLFEAGLFPGVNYYLSCWYKRSEFGIRAAVFFSAATVSGAFGGLLAAAISNMEGVGGKPAWAWIFIIEGLATVLAGAASFWIIQDFPDTAKFLTEEERAFVIRRLQEDDQFSAAGESFKFSYVWAAVKDWKTWVGMLCYTGVDGPLYAFSLFTPSIINQLGYTATPANLLSVPVYVWACILTCGVGWLADRRQTRAYFNLIFLTVGAAGYIILIASRNPALSYFAVYLAASGIYPLIPNTVAFVSNNTEGSYKRSVVLAMVIGFGNLNGAVSSNIYRAQDTPWYRLGHIIVLVYICIGFISTVVMMIGLKRENAARERGEKDEVIEGERPVGEKAVGDAKNGVYETVEDAKRDKGDQWSGYRYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G227</accession>
    <name>M5G227_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial cytochrome c oxidase subunit VIa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24782</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624715.1">
        <property type="nucleotide sequence ID" value="XM_040773848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G227"/>
    <dbReference type="STRING" id="1858805.M5G227"/>
    <dbReference type="GeneID" id="63688910"/>
    <dbReference type="HOGENOM" id="CLU_122515_0_2_1"/>
    <dbReference type="OMA" id="KLPWMVD"/>
    <dbReference type="OrthoDB" id="5947505at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02046">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="133" mass="15589" checksum="8099E1617D736D60" modified="2013-05-29" version="1">MTMLARLARTPLRAPLARRFATAELDPVHHAGVKSKFLEDREAVRHHAEQTTKLWRNISYLVCIPAIVGGYFWVMRVEGEHEAHQAHLREENGGHLPEKPHYEYLNIRRRAFPWGNNSLFFNPHTQRDMNVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2V6</accession>
    <name>M5G2V6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylose isomerase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_94154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629923.1">
        <property type="nucleotide sequence ID" value="XM_040777203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2V6"/>
    <dbReference type="STRING" id="1858805.M5G2V6"/>
    <dbReference type="GeneID" id="63692265"/>
    <dbReference type="HOGENOM" id="CLU_035063_0_2_1"/>
    <dbReference type="OMA" id="LLATHNM"/>
    <dbReference type="OrthoDB" id="5360893at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF21">
        <property type="entry name" value="XYLOSE ISOMERASE-LIKE TIM BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="2">
        <location>
            <begin position="76"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="380" mass="42282" checksum="7C37EEA3E688A8CB" modified="2013-05-29" version="1">MATFTSYGMPYRQLSEIPIAVASPSLGMNIVHTLPIKIKAAAEAKFAAIEIGMDDLIAYSRSLNPDLTPPHAKYHSTGAPTLEPDPRDPADDPLWSTLTSTALLVKSLCSELGLHVLTLHPLSQYEGWPEHTDRHAWAWEKALRWLDVASSLGAEMIQVGSNNELNASAGVDACAKDMLRLAQAAQERGVRVAYEPWCWGAYVNTWEGCWEIVQKANHPNLGLCLDTFQISGSPVYGASPTHPSGWILGYHPSVFTLSLHKLTESIPASKIFFLQISDGARLDPPLGRGNELDERWKGGWEPRQVWSAARRPLPFEDRGYLPVLEVVEAVLGTGFRGYFSYEPFEQEQEALDALIPDRYAQACRRAHEQLVAAVERKWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3H5</accession>
    <name>M5G3H5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_114103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631670.1">
        <property type="nucleotide sequence ID" value="XM_040769760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3H5"/>
    <dbReference type="STRING" id="1858805.M5G3H5"/>
    <dbReference type="GeneID" id="63684822"/>
    <dbReference type="HOGENOM" id="CLU_056776_4_1_1"/>
    <dbReference type="OMA" id="SINFLPC"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="37"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="139"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="192" mass="21368" checksum="C2BE7B628360E576" modified="2013-05-29" version="1">MAFLTSLCSCFTSQDREEEAVLAGDIHLPPAYVKRCVFCNVSREKGFDILHEVGPDPNSDDLIVFRDRAPAATEHLLAIPRHHLASVKALGKDDIQLVRNLQAASVQAFTELGFAPENQKLVLHPSFGFHVPPFNLINHLHLHCFGLPFRPSNEWKFHVALKQGGKGFSWFVEIGQVYEILGKGGKVKVLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3R1</accession>
    <name>M5G3R1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit TIM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Presequence translocated-associated motor subunit PAM18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_75865</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TIM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631775.1">
        <property type="nucleotide sequence ID" value="XM_040776164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3R1"/>
    <dbReference type="STRING" id="1858805.M5G3R1"/>
    <dbReference type="GeneID" id="63691226"/>
    <dbReference type="HOGENOM" id="CLU_017633_13_3_1"/>
    <dbReference type="OMA" id="HIMIANY"/>
    <dbReference type="OrthoDB" id="240298at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000001">
        <property type="entry name" value="Import inner membrane translocase subunit tim14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067561" description="Mitochondrial import inner membrane translocase subunit TIM14" evidence="12">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="13">
        <location>
            <begin position="51"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11662" checksum="83679E59A8764F39" modified="2013-05-29" version="1">MSTPILLGAAATLGAALVGRQLVKSGVIRFGKTASEEWAKGGFKSKMDRKEALDILGLKDNALIKNRLKDAHRHIMLANHPDRGGSPYLASKINEAKDLLEKLDGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3S7</accession>
    <name>M5G3S7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631795.1">
        <property type="nucleotide sequence ID" value="XM_040771948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3S7"/>
    <dbReference type="GeneID" id="63687010"/>
    <dbReference type="HOGENOM" id="CLU_3068622_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="53" mass="5875" checksum="D985A07DED66DC62" modified="2013-05-29" version="1">MVGAAALLFRVPQPALIWGLSDWDGRAEFSWFGLEVGKESASAVVGRRRVEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G428</accession>
    <name>M5G428_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-xylanase</fullName>
            <ecNumber evidence="9">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_117078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="9"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627489.1">
        <property type="nucleotide sequence ID" value="XM_040770315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G428"/>
    <dbReference type="STRING" id="1858805.M5G428"/>
    <dbReference type="GeneID" id="63685377"/>
    <dbReference type="HOGENOM" id="CLU_574969_0_0_1"/>
    <dbReference type="OMA" id="YIEHAFR"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF88">
        <property type="entry name" value="BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH10" evidence="10">
        <location>
            <begin position="36"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU00592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="404" mass="44545" checksum="51416824F3AD4D03" modified="2013-05-29" version="1">MHVLLLFLPALVLAQTIPNVSLLIDNPHLYSGKATIRTVLPLVSIRKGGPFHFGSTHDIFAPTAEAEWTSDKFSNVWNHIVAENGCKWYDTEPQPGVSNLTDCKGVQQYAIAHGASFRGHNTFWHSQLPSWLPGNVSASDLVNTVVPEHVAAEISGLGSYVTSWDVTNELIGDSTTMSMDAWECVQSANRWPTMTMDGGSVPLVTYLSFPYAAWSTALKYDPGKLVYNDYSTGATNDSKTECVFKLLADLHTNAHIPYTHMGVGFQSHIGAQPGSFVPKEQLETTFRRLAALGVDALITEMDMWIPTNTTAALRYQAAIWGDYIDACLYSSNCHEFIGWDTRDDVSWIKAGPGHGVAMPTLFDENGNPKPVYYEVLARFERYAAWKPEMCATALGVAECQVPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4A1</accession>
    <name>M5G4A1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_16625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040771211.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63686273"/>
    <dbReference type="HOGENOM" id="CLU_462327_0_0_1"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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            <end position="517"/>
        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="590" mass="66515" checksum="66B63C9E4E322B75" modified="2013-05-29" version="1">MEVVGSIPHQSSTSAGTAGVKRGQTASSACESSASSDWAQVELECQIVSMMHAPKENLQPSSSKAQSVDALQSWTAVHIGQYAKEVFHMWDRIAMREQAMVLHVEQRTEMNVQYWMPKLNAFLCMYGYLNISDHHPECLQNQLSNILRDCAFLHDSGIHLPTGSLGGLDLCHVPKDIWTLSAILSDIDSQLYLPPKLWGNEPDIMQLWDCTAKWFKFLEINPWPAPVKLQFLSHQNVMKMALIMFPSDLPHNSTLLNQTYTPTCFQSYALGRVPDVSMFSKSVPLENSRQPIGLLRLLDETHSKQDDWPAAWTVLSQLVRESNTENPQGHGPKRKNVAQTVASISLYTAEAKVNPFSGGNNDDEDLDMQSEQLNTSSTAKRCRPSRRNYTAHVSVREHPIQMEVDYYSLGLFSEPAWPHLPIVNRKQLLNRQRISIYTKTMEQAGHHNVVPVFLNNPEDLSAKFIREVGVVVTNWPGECSVIFQHGPFCCQDCQGSENPESKRKGGHKKVLQVHKPNEEDKPALKSIPYSVYSQPKDMYQSGNIPALTKIWQQLSHLLGWTCPWPQTRNKKKQAAKKTKQLASPELGEAI</sequence>
</entry>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <location>
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            <end position="68"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU03519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5I2</accession>
    <name>M5G5I2_DACPD</name>
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        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
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                <person name="Ohm R.A."/>
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                <person name="Rokas A."/>
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                <person name="Sabat G."/>
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                <person name="Syed K."/>
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            <strain evidence="6 7">DJM-731 SS1</strain>
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        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="23358" checksum="42D053C44A806AC3" modified="2013-05-29" version="1">MGISRSSRHKRSATGAQRPAYRKKRKFELGRQPANTKLGPKRVHTVRVRGGNLKYRALRLDTGNFAWGSEHCVRKTRIIAVVYNASNNELVRTNTLVKGAIIQVDATPFRQWYEQHYAQPVTKKGKQSEALSEEHKRSNHVQRVVESRKETAKIDPALDSQFAAGRLYASISSRPGQSGRCDGYILEGKELEFYVRKLRAGKSRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G666</accession>
    <name>M5G666_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632645.1">
        <property type="nucleotide sequence ID" value="XM_040771812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G666"/>
    <dbReference type="STRING" id="1858805.M5G666"/>
    <dbReference type="GeneID" id="63686874"/>
    <dbReference type="HOGENOM" id="CLU_025744_0_0_1"/>
    <dbReference type="OMA" id="YNTPYDA"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="244"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="564" mass="61969" checksum="373A48E2F8D914C8" modified="2013-05-29" version="1">MDACSDFDGTTVLGANDDARLSEKSTRPNKGKSVTPESSVPRNTLVPFVNTVEYLDQHRPFFVRCGEDGLIPALHKLNDQIVSAGHRSIMCKIQPMDFGREISPGQIGLVNRAGWPELLMQPGKYPGFPFRNWWARKFDGRQGVSDTVLQFQGLTAVQVSQNQAAVVSDPQNQIFVIRSGGFVALALQGTYDVLAVVDQTHLAKAITDKMTNQVLGYMQEVRMASTLGAKRNSQEYVVATFLNIPANNCAILQRGDELQQIPAGQHVITNPNVTFRSLFTRGECQIEMPAKDIMTKDQVPVSLTIYLKWQLEEPLKLTQHGYVSPYDALRDKSQSILTQIVAHLEYASMVKSRTLGPELEEHPGDSTAFLDSLRSRAMDDLHLAALEYGIVLKDLAVIDRKFKGEIAQTMDHLTRRALEAQVEAANVDRENSNRVKKEEGQLQVAQVQSKQRQAIADADAYTVVAKARADAQASAIAADARANAIRIQAAAEADAIKIKAQAVAEIRDEFAKEVELRRLEIQRVAAYGNRTVFVPASDPGMANNMTNALSVGMAAGMGRDAAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G686</accession>
    <name>M5G686_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_16077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628244.1">
        <property type="nucleotide sequence ID" value="XM_040771161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G686"/>
    <dbReference type="STRING" id="1858805.M5G686"/>
    <dbReference type="GeneID" id="63686223"/>
    <dbReference type="HOGENOM" id="CLU_044876_6_1_1"/>
    <dbReference type="OMA" id="FISAANW"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="33663" checksum="BA3AC6AF9AA23965" modified="2013-05-29" version="1">MPCYTRFAIAGASGTVGTHFLREFEHSVHGFDVTILTRREGGNELFAHEWAKKGAKIRPVDYEDETDLVRALSGIEVLISTVGASGFTLQVPLVRAAKKAGVKLYVNSHWGTPLTAEDLPEFAPLDELRTAALRVAEEIDLPWCEFRTGLFPEYCIPIPYAAGWLTRRLSERRATIYGDGNAQASWTTQFDTARYVLHVLRHLPFEELHNRRFNIQGDAKSFNQLVKLYETKHPGSAVEVIYRPLAELEEKVANSEGDDRFWEALMLAIVTGKAKHREETLDNKEYPAWHPRGVAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6J1</accession>
    <name>M5G6J1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_48216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631208.1">
        <property type="nucleotide sequence ID" value="XM_040774813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6J1"/>
    <dbReference type="STRING" id="1858805.M5G6J1"/>
    <dbReference type="GeneID" id="63689875"/>
    <dbReference type="HOGENOM" id="CLU_082772_0_0_1"/>
    <dbReference type="OMA" id="IYMGAYL"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039773">
        <property type="entry name" value="BAG_chaperone_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329:SF16">
        <property type="entry name" value="BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329">
        <property type="entry name" value="BCL2-ASSOCIATED ATHANOGENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="BAG" evidence="3">
        <location>
            <begin position="97"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20895" checksum="7AD255A933C74721" modified="2013-05-29" version="1">MEVTVKWGKEKIRVPLPPLETPLSEFRKSISDVTGLPPDGFKIIYSGAVLKDNTASLASFGVKPGRALAIVGLNEPLPTPSTAAAPVVKEKPTEQSTIERIRKELSMLTSTLSPELETFLEKGASVEKEEREATHTRLGELILQVLLRLDALMVEGWEEARKERRAAVKHAQDMLNRLDEGWKKMRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6V4</accession>
    <name>M5G6V4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_77739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630834.1">
        <property type="nucleotide sequence ID" value="XM_040776287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6V4"/>
    <dbReference type="STRING" id="1858805.M5G6V4"/>
    <dbReference type="GeneID" id="63691349"/>
    <dbReference type="HOGENOM" id="CLU_074846_2_1_1"/>
    <dbReference type="OMA" id="AEHMDYF"/>
    <dbReference type="OrthoDB" id="10044044at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="35"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="17492" checksum="21D7CF307FBCF222" modified="2013-05-29" version="1">MNCMKWVFGPCCCGCAYRGNDWQTADRKRLGPSLLAFFRQAMDFIHHLEMHHGIEEQHIFPVLQRKMPDFAKGAKHRNSHKGIHEGLDRLEALIKDYRNDPKTYSPVEFRACLDSFRDVLFSHLDEEVADLQGENLKKFCTLAEVQRLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G716</accession>
    <name>M5G716_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632930.1">
        <property type="nucleotide sequence ID" value="XM_040771473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G716"/>
    <dbReference type="STRING" id="1858805.M5G716"/>
    <dbReference type="GeneID" id="63686535"/>
    <dbReference type="HOGENOM" id="CLU_063728_0_0_1"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038955">
        <property type="entry name" value="PriA/CPL1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067549" description="Protein CPL1-like domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Protein CPL1-like" evidence="3">
        <location>
            <begin position="161"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="276" mass="29494" checksum="363C49D840F480B3" modified="2013-05-29" version="1">MLFSLLALALPLLPTALSLSLPDKRGEIDICAFVDVELIIDGIDFGIFRECVCLNIIDSIMDSNAVAQKAARKTSTGQVKNTIANTVTDSGGASQCIYPPHANPVCTETDPCAYTCIAPYAKRGGKCVLGASRRASKRDLPACASGLTQCGVWSHWGSRSYECLDTSVELESCGGCAIPYGDETPTGTDCTQIQGVSDVLCQEGRCVVLRCRPGWQVQEDGCVRSRPMAADVELAKSTLEEKQDNHTNSAARPGSSSLRNQNPLHMVADLLQSVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7A3</accession>
    <name>M5G7A3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628589.1">
        <property type="nucleotide sequence ID" value="XM_040768469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7A3"/>
    <dbReference type="GeneID" id="63683531"/>
    <dbReference type="HOGENOM" id="CLU_885732_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="314" mass="35499" checksum="E43BEC420605C533" modified="2013-05-29" version="1">MAAEFDASLNPDHLHGDRLSIMDICLSPKWPISYFTKVKVFKNLFRVLCENPIPCDMCGSNKVGQRCTGGWNYSDIDWKGDLKRVGQSCDSYWCKGYSCSFIVRNKEPAGESSKMANSKRKVTINLTGDNMKKPNKRAKSGTVKMEGELSFTIPDVVVSMEMAWRDVDSPAFLKYSGTFHKSFCHHFGSSSDTFRTVQCLHRLIHDSKRLHIAHAILSESFHVLHANIKRSGELDDDNFPIIVAPQNAREAADAIYHIKRGEPIPMVNEELEKAQAAYHHRHDNSSKKGESSCQVDKGKQWAKCEIFFFSLSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7A7</accession>
    <name>M5G7A7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_73414</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633010.1">
        <property type="nucleotide sequence ID" value="XM_040776007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7A7"/>
    <dbReference type="STRING" id="1858805.M5G7A7"/>
    <dbReference type="GeneID" id="63691069"/>
    <dbReference type="HOGENOM" id="CLU_002227_0_0_1"/>
    <dbReference type="OMA" id="QSRHNME"/>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16293">
        <property type="entry name" value="CPSF2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035639">
        <property type="entry name" value="CPSF2_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="6">
        <location>
            <begin position="300"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="641"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="653"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="925" mass="101196" checksum="5C1E0C6ECD7A2B6E" modified="2013-05-29" version="1">MIVFTPLCGSAQSTSVPNAFCYLLQIDDIRVLLDCGAPDWRLGAGEDVEGEDEAASRRETKKWWSEYLSLLTRTAPEIDLVLFTHGSLQHIGLYSYARAKLGLSAPAFATLPVQALGRIAVLEDVEGWRAEVDVDNEVPEEYSGDGDVKMESGIQLLHKAIATADVVKEAFDSITTLKYSQATQLTGKLQALTLTAYSASHTLGGTLWKLRSASSGTLLYAVGLNHMKEQHLDGTALVRPGGGGVGEGLGRPDLLITDAGRVGIISVRRREREEAFLESITNTLRSSGSVLIPVDASTRLVELLIILDQHWTQAKTRAPLCLVSRTGKECVTFVRSLMEWMGGWITREGEVPTIGKDSKKRKRRNRKDEEDIEEEDALLANMILRFKHLQIFPSPEALMDAIHPSAPKVILATPLTMSHGASRAMFESFSSMRNNLLLLVNIAEKGTLARSLWDIWQREQAETAKWGKGRLGAIVKAETDISVRMNAKVPLAGVELEEYLNAEKAAKEKAAAEAAARPQLLLEADDDDEGDSEDEASDASSELAVEEELGGGTDEGVATRHFAEGSGAKGAGAEEEEADSARQQLSFDIYLKGKVARATFFKSSSGAQATRYRMFPYVEKRRRIDEWGETIDVGTWMRRGKKWEEEEETEENQAAKEARRKRQEEEQAQHAPPEPPSKYITEQHSIDVRCKVYFVDFEGLNDGRATKMIVPQVNPRKMILVASQPEATAELMQACGEIRSMTREISTPGVGEEVKIGEHSHSYSISVGETLFSTLKMSKFEDNEVAFVSGRIAFNPNSAIPVLEPAASAKSQDSAVVPTGTDQAREEQTMIATVPAQILPQTTLIGDLRLTALKARLSTLGITADFAGEGVLICGLSQTGNGGSDTDIVSVRKMGRGRVEVAGNVSDVYYTVRRELYGLYAQVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7C0</accession>
    <name>M5G7C0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_22146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628619.1">
        <property type="nucleotide sequence ID" value="XM_040772700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7C0"/>
    <dbReference type="STRING" id="1858805.M5G7C0"/>
    <dbReference type="GeneID" id="63687762"/>
    <dbReference type="HOGENOM" id="CLU_929243_0_0_1"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="9">
        <location>
            <begin position="99"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="33107" checksum="046781355B604A82" modified="2013-05-29" version="1" fragment="single">MHDTRDLGSEKSHNSRPYGTHFLKIVTHSPTAAESRKSNRNGGCPCCSSGTAFKPRRPRPDCHSILWSLLPSISFLDSRLGPCRILSPHERYHPLPPYRAHYLGSSSPKSDPALYLSAVEALLQSFRLELQFPFLMEAENGRVSDVVPLVVNTMGWTKGLGARLLEQVEQLVQPTHVFEFPDSGETAHPLDQFPSSTLTPTGNGDDRQVYTLEPVQPSPRLSAYNAPLLRALSTMSYLHSHPPQEGQSTRWSTTPLCAQLPYEVDLRTAFDKIVLVGPGSEDVVPEELGTVLNGSLVAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G874</accession>
    <name>M5G874_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="137" mass="14503" checksum="37C3DC4AD968696E" modified="2013-05-29" version="1">MPTLDVPGASLSYETHGSGPLIVFIPGGQGTGDVYHPIATALAAKYTSVTYDRRGFSASILTSDGTAVVFGSSSGAIVALFLLLSYPESIRTVIPHEPPAIDLQDRRADSGVSEVRREYVRRNGASNVQTEVGDAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K4</accession>
    <name>M5G8K4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_54798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8K4"/>
    <dbReference type="STRING" id="1858805.M5G8K4"/>
    <dbReference type="GeneID" id="63690346"/>
    <dbReference type="HOGENOM" id="CLU_004966_3_1_1"/>
    <dbReference type="OMA" id="MRRERYC"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305:SF1">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="17395" checksum="2E00C2D60DA9D358" modified="2013-05-29" version="1" fragment="single">SPPPQAMPDVMFYDNNCHLHQYLSGQGPIQEHFSKTALVVDIFHFKNHHSTADQYCSTHCNPMAFPQLYNQQSGQWTFNSSACEQTNAWLGNFDGIVQEMLPVRYEFFLDEVIKAHNCFHVEELLHNNALPYLMDRSLLLNGLKPAWHSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8N8</accession>
    <name>M5G8N8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629099.1">
        <property type="nucleotide sequence ID" value="XM_040772611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8N8"/>
    <dbReference type="STRING" id="1858805.M5G8N8"/>
    <dbReference type="GeneID" id="63687673"/>
    <dbReference type="HOGENOM" id="CLU_662256_0_0_1"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="415" mass="45638" checksum="3DD2D2C2932CC7BE" modified="2013-05-29" version="1">MCRQSRILFRRRAEHTVDNNVGFNLVTFAMEKLLGTSATSHYDDGQNLAILARRIPIDMRTNTSAALMLTNRQLAQHMRVLYAVTDDNETLITGSPSEPIVSEGAKTAMSHTGFDVVNALGGILKSPGISVGERGEMMAELLLILASDAATVEAKGKFSIPTFFEHLLTDSSWNVLKGTSASRGAKEFHAGTFQHTFKNSYGNFNHIIKVHNNVLESKSWYRHLSRRAGISARFGERGIDGAFPITINGTKIAPDNISCLVFQIKAVEAMQRPSKLVFDKMDDPVLGTDDSDDTDSTSAKPVIRLVFSLRSHEKDVIVMKYTDDYDNELLTWDIFVLFSSLRAVKKNPKAWQTVLDMASSEGKMYGSNVTLMGMDPGAGIGDNFWPNWVTTGKKTTEDGSEAKAKASSKGKGRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y0</accession>
    <name>M5G8Y0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627120.1">
        <property type="nucleotide sequence ID" value="XM_040773148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Y0"/>
    <dbReference type="STRING" id="1858805.M5G8Y0"/>
    <dbReference type="GeneID" id="63688210"/>
    <dbReference type="HOGENOM" id="CLU_1085952_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="256" mass="30142" checksum="5713623B63AD3607" modified="2013-05-29" version="1">MFSLWPTFSRWPRLSLWLIWTTAETMLASLLKQVKSILYWDDRPVILDDDDVNIWPPNIRPRNIKRALNRRMHGRGRCVDVRYLSHGASHVVLLAKTSYKEEYVVRVTGSVYEHFQWAHPFWQTYKETSEVASMVALRRLTKIPVPRVYLFDEDRDNAVGGVWTLQDYMEGERLYEFLPELSGEALEQVRAQLANWMLQVFHLEFSQIGSLHFTRSLNEIRDVSDDDLEIRVGRLVTLRGLRMENDYRVGPPKDMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9S0</accession>
    <name>M5G9S0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">p-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_117068</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627475.1">
        <property type="nucleotide sequence ID" value="XM_040770312.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G9S0"/>
    <dbReference type="GeneID" id="63685374"/>
    <dbReference type="HOGENOM" id="CLU_000604_27_6_1"/>
    <dbReference type="OMA" id="AITYWLS"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="787"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="827"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="917"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="201"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="513"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="794"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU00578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1386" mass="154317" checksum="C11B6D765C5A3DD4" modified="2013-05-29" version="1">MVKLKRERRWEGVACLTVLVYTLHLATLRLRPSFLRPRLTWHINSLVILLSLSSLTTSLLPLLLLQPSPLTHLSPYGLILFTLLLLFIICVGLTPRYAHPIPGYPISPEQTTPPIQYFFTYLWLQPLVRLGYARKLELDDLPPLPAYDDPEVWRREVEWARKGEWLPKWIRRWVPSKQGKIRRTLLTVILCLRRNIAGQCLFALGMALFDLGGPIAMNRLLRYLETPSSAGIKPAIWVFFMFAMPVLKGACWQAYLFISTRLIVRVRLAFIQELYAVTLRAKLLARPASKEDESIVGRISNLMSTDVENIFGARDIVHISVTAPIECTIAVIFLYNIMGASSLFGFLVMLVSIPLPAFLTRQLTACQRQVLRYTDARMGTITELLHSIKVFKAFGWDPVVIERVHAVRAKELARMWMRNIWSVAIVTTADCTPMLTMLVTFFFHTVVMHHRLDSSVAFTAMAVFELLRQQFVYASNIARLCANAVASIGRLNAFLQEQADHEIAESRRAGQVIQITDDAPWIQDGTFEWPSTGFRLQKLNVRFVKGALNAIVGPTGSGKSSLLLALLGEMPIVQGQCCLPRMPRGIAYVSQSSWLRNATVRENILFGCAYDEMRYHRVLFACGLIPDLRLMEYGDQTELGEKGATLSGGQRARLSFARAVYSSAHTLLLDDVFSALDVHTVHHVFDNCIRGEILQERTVILVTHFEDLVAPVAALVLRVVDGRLEEVRLAEPAQDTSASEETVIEPELPPIHSILNGNPNAIRLVKDEERAVGRLPKTMIFRYMLQFGGWPVFILAISVACGTQLAFLSTTFWVALWTNAQNSMSHLGYYCGGFAIVLAIYVCLSATSSIILYSGAWNAARKIHMWVTIAVFRSPIGWFDTNPLGRIQNRFSRDFLSVDTLILPLLKMVVDNALRAIFRLAAITTILPVFAVPAIFTTYFAYWAGNLYTATQMSVKRIVAVEQSPIFNSIADTLRGAETIRAFDVQPMFLSQLQAALARSSRALEANFNSNRWFCVRIDWASGIVAVSAGALALYMNNPNASLVGFSLNNAVGMSLTLMTLLRGLNDFEVELVSYQRLMEYTMLKTEPTPTPQGKPPAAWPIAGRIEVRNLRVRYFDDAPDVLKDLSFTIRPGEKVGIVGRTGSGKSTLALALLRLIPKASGQIMIDDIDIDTLNLDDLRQAISLIPQEPLLFSGTTRTNLDPFDAHDDAELNVALNSSGIVESMRPSRTQSRTASTVGLESITKGSSPESPEGEKVITLETLVAEGGQNFSQGQRQILALVRAIVRRCKVLLLDEATASVDRDTDERIQASLQAEFGNCTILTIAHRLRSIITFDKVLVLDKGEIKEFDTPSNLIRSGGIFASLVEKGADADELKALAGVQGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9S6</accession>
    <name>M5G9S6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NIPSNAP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629521.1">
        <property type="nucleotide sequence ID" value="XM_040772490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9S6"/>
    <dbReference type="STRING" id="1858805.M5G9S6"/>
    <dbReference type="GeneID" id="63687552"/>
    <dbReference type="HOGENOM" id="CLU_053393_0_1_1"/>
    <dbReference type="OMA" id="REKSWSV"/>
    <dbReference type="OrthoDB" id="10262843at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000004">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="169"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="268" mass="30497" checksum="EC7ED820E2A88075" modified="2013-05-29" version="1">MSLLATLPRRALSRPSALATRGITLDAILHGSPEAKAEGEVAILQHSRLVARGKYVHELLTHRVKPEAVDEYRTHIGKYLTGIASNPEFHVKLSGSWEKIVGEQDTFVHILEYENYAGHDKSTKLIRGSALHKHFKENVLPHVRSRTSQICQEFAFLPTSPPLTKGGIYEMRSYQLRPGTLLEWEHTWRRGLDARKHFVKPVGAWFSQVGRLHQVYHIWQYADLNARKEAREQAWQLEGWSATVNQTAKLATSMDSEILIPLPFSPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA03</accession>
    <name>M5GA03_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetraspanin Tsp2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_21716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629626.1">
        <property type="nucleotide sequence ID" value="XM_040772517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA03"/>
    <dbReference type="STRING" id="1858805.M5GA03"/>
    <dbReference type="GeneID" id="63687579"/>
    <dbReference type="HOGENOM" id="CLU_030826_0_0_1"/>
    <dbReference type="OMA" id="GCKGPYI"/>
    <dbReference type="OrthoDB" id="2156690at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="49091" checksum="5A0E486371AA76C8" modified="2013-05-29" version="1">MPSLSTPPTTAGPAYASTSTSSLTPPTPPFATNLGTRPMSRPMSRPMSIQFHSRSSSIPSDPSARLSLNYIPAKFSAPYAGNSLRSRRSGLKELSASRPRGGGRAAFAQEESRMAGEGEEDDAWDEKEVDKPKPRLRWNRFKWALFVTNFFITAYTLTALVFLILTWFNTLPSADVVRTANHPELVISTVAASLGLLTSLIGWSGILLNNRAFLGVYCLLLWISFAFLCAPGYVTYKRRTFNLEGKINSLWSREIGVSGRLRIQNQLTCCGYYSPFVEASTSSTCYARSLLPGCKARILRFERNTLQNWYTVAFALVPLHLVAIVVSLLCSNHVTYRFGKGMMPNAYRLNRSSMAVLMDSYATQLAEQYNNAPSSSADGTQRKPRGNSDSQSPYHDKYAVLGPSNAGVIPGTSSGTGTSSGPGTGTSLRAPSVERSGSESESYEMEPVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAW0</accession>
    <name>M5GAW0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630011.1">
        <property type="nucleotide sequence ID" value="XM_040774977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAW0"/>
    <dbReference type="GeneID" id="63690039"/>
    <dbReference type="HOGENOM" id="CLU_006344_8_3_1"/>
    <dbReference type="OMA" id="CRAHRDS"/>
    <dbReference type="OrthoDB" id="2418900at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="16579" checksum="3E0167D467B998F4" modified="2013-05-29" version="1">MWTGNWWWRTQTQLPSGVTIIPIILSSNKTLLTQHSGDWYGYPLYISIENLPKAVRKCPSQQGTILLAYLPTDKFEGMGLSKEAAKLAHHGLYHQSLSHILKDIVLPGREGITMTTADGVVRLCFPILGACMCNYPPEQCLLTCTQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAZ1</accession>
    <name>M5GAZ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_78031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RICTOR family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630046.1">
        <property type="nucleotide sequence ID" value="XM_040776306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAZ1"/>
    <dbReference type="STRING" id="1858805.M5GAZ1"/>
    <dbReference type="GeneID" id="63691368"/>
    <dbReference type="HOGENOM" id="CLU_001013_0_1_1"/>
    <dbReference type="OMA" id="PEWYQTF"/>
    <dbReference type="OrthoDB" id="271111at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028268">
        <property type="entry name" value="Pianissimo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028267">
        <property type="entry name" value="Pianissimo_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029453">
        <property type="entry name" value="Rictor_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029451">
        <property type="entry name" value="RICTOR_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029452">
        <property type="entry name" value="RICTOR_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298">
        <property type="entry name" value="CYTOSOLIC REGULATOR PIANISSIMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298:SF11">
        <property type="entry name" value="RAPAMYCIN-INSENSITIVE COMPANION OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14663">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14666">
        <property type="entry name" value="RICTOR_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14664">
        <property type="entry name" value="RICTOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14668">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01303">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01307">
        <property type="entry name" value="RICTOR_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01308">
        <property type="entry name" value="RICTOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01310">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR N-terminal" evidence="4">
        <location>
            <begin position="41"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR middle" evidence="3">
        <location>
            <begin position="501"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR" evidence="5">
        <location>
            <begin position="894"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1102"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1173" mass="132098" checksum="668E4D2A52236AA9" modified="2013-05-29" version="1">MEDFKGALASSRGLVGQLAELGRLDDAGGGSGITVAEGARLACVGRLTEILRVNVRVRYELDISEFAQAVMPCLADACSKDLRMAVFRLLRFTIVDATALGVLKDEGLDWYMIKTLSRDNKHVEEKEQVLKLIRLFLTLRSEPQPQNSNSNPSPPPPAPPISEPLLRAFIAMCDSSEDALRLTGLETLAELVLVDIDAVCLSGGMRVLLQALAEGAEVGPALAGVFLYLIDRPRTRGYFRLGSDLESVFSVFSEVYGTRQSINTARLRACSKTISSMLRTWAGLLYFSLNDRRAIATLVNTLRFPIPESREILIDFFFELLRIRGAKWHGEFLQGRRLTLYGRGALGAPKGPNPALEPLNARLDLSDQFVALLVSIFIEAGLLDALAVVIQEKGGNEGVARRAALLMDEVLQIVSRVLPGRVSSTILSLPALFAMTTSFKDNDQRNIGIDTLASLDSLDRNRLRLQAQPQTNRNRSNSVDDAIRRGQRQAEQTRKTMAAAVDDKTFATMIVDTGVTTSRDSVRWNVDLLLEVMDGALSSSKRLEEVLKTSKFCRRLLPFFHPFAHRFSDLRSTKPNERWVKLGCKFLRVLMSHSEGQRMLTEDKLLLELMECFAQLDPFNGAPSSDPIFSKKRVEDTLTYGYFEMLGTLSQFSEGIELLQRFRIFTAFYHLSELKSREDLIKGMIEHLDYSRDGHPRIVLSKALTSSYKHIRKYATEHLGKLIQNSDEPHEWTLRLLLTQLYDPAVEVCEQAVEYLQEACQSSEVLQMVVRMRPTLEHLGELGHPLLLRFMSNQAGFRYLREARYVDREMDGWFQERNLQYVIQVEAFLAKALGQEDTEEFLNPDFDGMAPPHFYGEMAKTELGCQIIHEKGHFADFAQVIRQYGLEDEDRELITKLKSVLWAVGNIGSHHYGFQFIEEEDILQNIIDIVEQSAVLSVRGTAYFVLGLLSCTSEGAEILYEYGWEATKTPMGEPTGICLPIAQGEKMERFLDIPLWEPPLRIYMEPRMLRPPTAPVENDVLLAIANLGNSMTANKASHTLALLKTRHHKLFSSITLLYRVLHLISTHSYRFSVRKYVLDLFEVRFDPKTVAALRKAASSLQQVGPAEVEQAAPRPRDSLRSRGRTRSISDDEELGLGLEGEEEGEGVEEEQQRGVWMEPQVKVTGFDDPRVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB66</accession>
    <name>M5GB66_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22939</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the cut8/STS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628090.1">
        <property type="nucleotide sequence ID" value="XM_040773025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB66"/>
    <dbReference type="STRING" id="1858805.M5GB66"/>
    <dbReference type="GeneID" id="63688087"/>
    <dbReference type="HOGENOM" id="CLU_056224_0_0_1"/>
    <dbReference type="OMA" id="KDAYPYS"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="372" mass="40467" checksum="FC666C4D78B2EFA5" modified="2013-05-29" version="1">MATVQIPFSHRSNPSSPFAHKFSTHHKFPSPPPPSTFSHPHPNNVTSPSRWNSPAKRKHEGADDYPDDEHREQDSTQRRIAGGKRVKRGDDTIKPNESDRQAIPGSMEVKNEMEDVDVGVLLASVPQSSLLPLLNALINDNPSLKPKVISLMPRPSIGAVTAALGAAYQKVQAAYPYSSSTPTFSGGGFGMSFQPIAPSSFGFGSAFGTPLSLQASGLQQPRDSFARARLRQPLAEFVTTVLSYLPYFSLTPATSASSVSASSKQQPHAGETFTYLHQAAQYALQLLPLFGPPTPPPADLVDLIQRLHTEVTAWSQAVAVHVNKNGGMFGSDMVQTWSRGLDELAQLGGEQWGQLRDEWVQQCGWLIGRRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBD4</accession>
    <name>M5GBD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630256.1">
        <property type="nucleotide sequence ID" value="XM_040768281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBD4"/>
    <dbReference type="GeneID" id="63683343"/>
    <dbReference type="HOGENOM" id="CLU_2170980_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067732" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11894" checksum="054BB22EAB8B83AD" modified="2013-05-29" version="1">MLLVLVLVLVLVLAWARMAASGLAGWRVSGLAGWVDFRKGCASGWGVWYSSARALGHSSSGTQALGHSGTLALKHEHSSTRALRHSDTQARPSMLGLRHSGTKEHFRYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBS5</accession>
    <name>M5GBS5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630411.1">
        <property type="nucleotide sequence ID" value="XM_040768129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBS5"/>
    <dbReference type="STRING" id="1858805.M5GBS5"/>
    <dbReference type="GeneID" id="63683191"/>
    <dbReference type="HOGENOM" id="CLU_808977_0_0_1"/>
    <dbReference type="OrthoDB" id="3357985at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="57"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="343" mass="39036" checksum="A1D33498D10F6089" modified="2013-05-29" version="1">MSHAPPPSPARAPAPSRPRTPAPSHTCRPRTPSSRPRTPAPALDVQVTLPPSLRASADLVIQSSDGTQFRVHKAYLAASSRFFEDMFGDETLAFLNESREDKQLPVVELSESRYTLRTLLPCVYPGTKPRPPSLRVLRDTLVAADKYDMPSVRDSMRPHLVWPEFLSTNPLLVWAISRLLEFEEEKKIAMEALFELNEEELFALEMDGVAASDLAVVHLRRQQRADAIIRVVQDVLAKDEGDKTPANCYRPICKVCKRVPMWVYVWTKRLEIDARKRPTIDKLFSYTSLENARQKSPRCRCSPDLIMWDPKSFDDLKKIVEDSVQPVKKRKSSLRLSKRFATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBT7</accession>
    <name>M5GBT7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_113916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632799.1">
        <property type="nucleotide sequence ID" value="XM_040769724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBT7"/>
    <dbReference type="STRING" id="1858805.M5GBT7"/>
    <dbReference type="GeneID" id="63684786"/>
    <dbReference type="HOGENOM" id="CLU_037990_2_3_1"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="286" mass="31760" checksum="AEB63AC5490FA1A3" modified="2013-05-29" version="1">MPNPTDDAKCKVAADWTRDLTIQGWRKWQPEMHAGSEETSRLIINLGGIDSGMRVLDLASGSGDPALSIAHVVGGEGHVIATDMSEGMLRIAQDCAEKEGLGNLSFRVADMEQLPFEDASFDRVTCRFGIMFVPDHVRAMREMLRVLKPGGKVVLVCWAHWDQPFHAGNIAIIKRGLGPAPPPGTQALTPFRFQEAGTLGTAMRQAGLENVQEQECRVPWDFPGSAKRFWEMWYDIAAPYRSIIDGLEPKEREEFVREVLEVWTPRENGPFLHLGVRIVVGVGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBW1</accession>
    <name>M5GBW1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_73163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632834.1">
        <property type="nucleotide sequence ID" value="XM_040775993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBW1"/>
    <dbReference type="STRING" id="1858805.M5GBW1"/>
    <dbReference type="GeneID" id="63691055"/>
    <dbReference type="HOGENOM" id="CLU_019414_0_0_1"/>
    <dbReference type="OMA" id="RIDIRYG"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="426" mass="48419" checksum="975E74D2C03ACD43" modified="2013-05-29" version="1">MATYSPKPFTVHFSDDKVKEMYDSLASSHLLEHEVPSMTWDDGITLDRLKELKRKFETGFNWRKVEAEMNAVPHYTVEIEGMTLHYVHQPSPDEGAIPLILMHGWPGTFWDFAKVIEELHKPSGPCMPSFNVVIPSMPGYGFSSLPRKAWTLEDTGRVYNKLMTEVLGYKTYFAQGGDWGSMILRIMASVYPSCRLAHFNMFRCPPGGLLAYAEYIDYLAPVPLIGGYVKSMKAVARSWILSPTDVKMVRRHEDFSESGRGYALIQGTRPSTIGYAIHTPLALLAYIGEKFQAWSDPTLLSDKDILATVALYYLTNTFHSSVIVYKMSGKARNDMATSSTLWRIKCRFGFSYFPYEIGAMNYGSISRCGPLVFYKAHAKGGHFPALDVPRDFISDLREMASRYWWTKDTYMVKSINKKFDKPEGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBY7</accession>
    <name>M5GBY7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633413.1">
        <property type="nucleotide sequence ID" value="XM_040767758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBY7"/>
    <dbReference type="STRING" id="1858805.M5GBY7"/>
    <dbReference type="GeneID" id="63682820"/>
    <dbReference type="HOGENOM" id="CLU_2454695_0_0_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9540" checksum="BAE35B769F60D3AB" modified="2013-05-29" version="1">MATITEQGGIPQLNASTGTGTGIWLLDMAKSVPSSVTLVGVDIQSRLFPPAQPNMKFFVGSTFDLPTEMDCTFALVHQRLMVAAFSYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC25</accession>
    <name>M5GC25_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TspO/MBR-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_19359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632924.1">
        <property type="nucleotide sequence ID" value="XM_040771469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC25"/>
    <dbReference type="STRING" id="1858805.M5GC25"/>
    <dbReference type="GeneID" id="63686531"/>
    <dbReference type="HOGENOM" id="CLU_091805_0_1_1"/>
    <dbReference type="OMA" id="WSWLFFG"/>
    <dbReference type="OrthoDB" id="8841220at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.100:FF:000001">
        <property type="entry name" value="translocator protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="187" mass="20382" checksum="BEAD0C05818F4B11" modified="2013-05-29" version="1" fragment="single">MPIIALPPLLVELPRSPILAVGIPIVLGSLSGFPTLKVAASSWYNGLKAPPGRPPRQVFAFVWPVLYAAMGYASHIAVRSLDNSLSPVTKQAAADGLALYWGQLALNLAWTPIFFGLKNRLVGLIDLSALTGAAYYMTYKLHEATEGKTTYFLGPYCAWLTFALYLNGGVWYMNRNYELKGKGKADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC68</accession>
    <name>M5GC68_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonylcarbamoyl-AMP synthase</fullName>
            <ecNumber evidence="3">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_19699</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUA5 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633518.1">
        <property type="nucleotide sequence ID" value="XM_040771621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC68"/>
    <dbReference type="STRING" id="1858805.M5GC68"/>
    <dbReference type="GeneID" id="63686683"/>
    <dbReference type="HOGENOM" id="CLU_031397_0_1_1"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="14">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU06624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="248" mass="26881" checksum="9047CF980995A5F2" modified="2013-05-29" version="1">MPSHPIARAVISLSHTPLAAPSANASGRPSPTRAQHVLTDLGGKIPLILDGGACDVGVESTVVDGLSSPGVIKVLRPGGLTVEELQRVLGPGTKVLVHKRDYEDPEIEHVPTTPGMKYRHYSPTTPVVLLLRTTPPEGKKAESIHDILDELHDELSPQQEDFRVGVLAFSNSPITLACITTHYHTHRYSLGNRNEPSEAAHRLFDGLLTLDAEGVDIILVEGVEEDREGLAVMNRLRKAAGEVRYIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCN3</accession>
    <name>M5GCN3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628775.1">
        <property type="nucleotide sequence ID" value="XM_040772740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCN3"/>
    <dbReference type="STRING" id="1858805.M5GCN3"/>
    <dbReference type="GeneID" id="63687802"/>
    <dbReference type="HOGENOM" id="CLU_043312_0_0_1"/>
    <dbReference type="OMA" id="KKWAGAK"/>
    <dbReference type="OrthoDB" id="5390558at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04774">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01233">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="2">
        <location>
            <begin position="98"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="326" mass="34387" checksum="652B42BBF3C1FA2F" modified="2013-05-29" version="1">MSVASKNPFALLDDDETVEQTSVAVAVPASAVKPNEQPKVQENRSRQTNGRAPRTPRPERTADGFEVKEGRGERRGRGEGRGEGRGRSRGGRGRGRGGFQNMDRHSNTGITDSHKQVHQGWGGDTGAAEHAAETEGAADAIKEEAAPEAAVNGQEAPVTPAGEAKPTEEAEGKPRVEEEEDNTVSYDEYLKKQKGTPGVLDNLIPKLEVRQVGEGEGYEDGVLSRGGAEVLKKEDQAFFAGKTKKDPVSKPKKEKPVMIEIDARFAPVERGGRGRGRGGERGGPRGRGEGRGRGGAGAPRGRGVSRGGAGRGVDVDDAAAFPSLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD40</accession>
    <name>M5GD40_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S12/S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_20828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631126.1">
        <property type="nucleotide sequence ID" value="XM_040772101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD40"/>
    <dbReference type="STRING" id="1858805.M5GD40"/>
    <dbReference type="GeneID" id="63687163"/>
    <dbReference type="HOGENOM" id="CLU_115574_0_1_1"/>
    <dbReference type="OMA" id="KFRWSQR"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="145" mass="16041" checksum="73619652CD7161FE" modified="2013-05-29" version="1">MGSNKPRGLQAARKLRNTRRDNRWADKNYKKRALGNIYKTSPTGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPRDGCLNFVDENDEVLISGFGRRGKAKGDIPGVRFKVVKVSGVGLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDC6</accession>
    <name>M5GDC6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_105493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDC6"/>
    <dbReference type="STRING" id="1858805.M5GDC6"/>
    <dbReference type="GeneID" id="63683158"/>
    <dbReference type="HOGENOM" id="CLU_1408717_0_0_1"/>
    <dbReference type="OrthoDB" id="3265339at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="193" mass="20557" checksum="73BDF43C6A855FB9" modified="2013-05-29" version="1">MASSSKGVAKDTPSHSKHPGHVKWAPAPASDEHRPLLDDDIERADEEDNGQDNSSGSVSRLHRTSKIGLLLGHGRRPSYSGISEEGRQAPGSWRWWLHVFASALVALLVVAVIIAAIKSGEDDHPTGPYPEPPHHTTAATGTFSVPHVEPTGKPRNPAYMIKAIHGAVATENEKCSEMGVDILKAIGCDSSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
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    <name>M5GDD2_DACPD</name>
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            <fullName evidence="4">t-SNARE coiled-coil homology domain-containing protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_21982</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="M5GDD2"/>
    <dbReference type="GeneID" id="63687688"/>
    <dbReference type="HOGENOM" id="CLU_1475133_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="Gene3D" id="1.20.5.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21100" checksum="B5EDE92F3ED8DCD3" modified="2013-05-29" version="1">MPPLLLHRYGEIPALNNPLTLDDLRTADEYIEFVLERRDKVPRGVPLATQQHLTSAIMWKERMRTEMCNTYYAAADIHPEQEAGMGQLMQHPGQMQQALQQSLHDGLAGVHERMDNLQANMQQMFTDVQQNLDQSFAGMEARLTGIEGRLIRIEERLTNIEADGHSSKNRRGRREGHRDRRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDG6</accession>
    <name>M5GDG6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_48581</name>
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    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="306" mass="34392" checksum="745A6987935F560B" modified="2013-05-29" version="1" fragment="single">DFSRASYASIARKVGLDASFSLQDVPTFPLHRARIPTSLFKEIVGDIELAVKQYGLPHEQDNEATRSRFISSVSLDLLFARLSSHFELLLHASLDNSVQTRYADDRVQYTWRMLGQVAIILIHNKDEAISGHEHLNAIAHVIAECISCDFLNYELGYEPARIYAIYSDGTSFDFFRFDGSSNPRFARGIQTVPNAFPKARLTLTLPETASQLGSFITSLRPVCEAIFYFFMLGYEACLDTYCSEAINTTPESIIHRMRRTMPWGESTERIKSALYLALAAGEAAVRGDLETAEQTARSALKKLKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDM3</accession>
    <name>M5GDM3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_15230</name>
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    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629427.1">
        <property type="nucleotide sequence ID" value="XM_040771084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDM3"/>
    <dbReference type="GeneID" id="63686146"/>
    <dbReference type="HOGENOM" id="CLU_1948752_0_0_1"/>
    <dbReference type="OrthoDB" id="3339134at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="129" mass="13967" checksum="9EE9D842EDE31D22" modified="2013-05-29" version="1">MESQLYSLLARHDQIESIVPNIDAVVPRLVFELGGYASSTKAKVKVTGLVFMSDLEFIFEGIKKKFGGKNIGVPLVGGKCELQIVTTILALNVNFLRSGKIFAMFIGVYPGLSAANGIFTGQGQWLNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDW8</accession>
    <name>M5GDW8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629652.1">
        <property type="nucleotide sequence ID" value="XM_040775012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDW8"/>
    <dbReference type="STRING" id="1858805.M5GDW8"/>
    <dbReference type="GeneID" id="63690074"/>
    <dbReference type="HOGENOM" id="CLU_092523_1_0_1"/>
    <dbReference type="OMA" id="HTHEMAF"/>
    <dbReference type="OrthoDB" id="5599163at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="97" mass="11504" checksum="E2517BBDBCA046B5" modified="2013-05-29" version="1">MNLNATKFLWPAKVNLIKWVLHTHEMAFLWDEVKIRWFHSNYFNLVVFPTIEHTPWQHKNILLAPALLDQVIQTICKKIQAGVLIQPKRGPKYQESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDZ8</accession>
    <name>M5GDZ8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631851.1">
        <property type="nucleotide sequence ID" value="XM_040771968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDZ8"/>
    <dbReference type="GeneID" id="63687030"/>
    <dbReference type="HOGENOM" id="CLU_2158263_0_0_1"/>
    <dbReference type="OrthoDB" id="10590800at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="11498" checksum="6268C51A3A568D69" modified="2013-05-29" version="1">MSSSTESSTPASSSSSSSSSSSTSPSPPTQPMPDLPTTPSTHPQAIEPRAARLARVAEEVVAALAARQMGDPAMLNADIVRGSIRTLNEIIQESASTNASYNINVWAGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE15</accession>
    <name>M5GE15_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631891.1">
        <property type="nucleotide sequence ID" value="XM_040771985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE15"/>
    <dbReference type="STRING" id="1858805.M5GE15"/>
    <dbReference type="GeneID" id="63687047"/>
    <dbReference type="HOGENOM" id="CLU_985344_0_0_1"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053027">
        <property type="entry name" value="AGGF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106:SF24">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="119"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="283" mass="30645" checksum="910651D64FBDD132" modified="2013-05-29" version="1" fragment="single">MSLLKLPTPRRLHNPHDSPALSEDELSASASASADEDRESGEISEPEHDQPSFKGYKPEYEWPGTEADFPPSGPSDPLPTPVFDRPLATTDLRLVVLSTSGYSFLRGKTVAVINTSEGCSIGRDSAPGPRLRLREMPVSKFHASIFWDSGLASWAVVDMGSMHGTFVHTTGSEPVRLSPPRVASQPRALKHLDNLIIGSTTFLVHAHKDGLPCEVCFAPQEKEIPLYEENKNGKSESSSTTAYGPTLSSTQKRVKHKHDMSSLKSSLLSTLPTPATTPGSGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE63</accession>
    <name>M5GE63_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DDE-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_35729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774397.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63689459"/>
    <dbReference type="HOGENOM" id="CLU_018294_5_2_1"/>
    <dbReference type="OMA" id="QRNITIY"/>
    <dbReference type="OrthoDB" id="162969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="69"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="125" mass="14091" checksum="FB20AD7825A029C7" modified="2013-05-29" version="1" fragment="single">GLRGVQLQGEAASVDVEKAEEEVLHLRKITNQYALQDIFNGDETSLFYQMPPNCTLATMACSGRKGDKTHMSYMLTTNADGSEWLKPLVFGHSKQPCCFQHKTPQSLGFDYHFNKKAWMTGVIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEQ4</accession>
    <name>M5GEQ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632496.1">
        <property type="nucleotide sequence ID" value="XM_040767876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEQ4"/>
    <dbReference type="GeneID" id="63682938"/>
    <dbReference type="HOGENOM" id="CLU_1722305_0_0_1"/>
    <dbReference type="OrthoDB" id="2392202at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="17413" checksum="34CCE50887D3966D" modified="2013-05-29" version="1">MDEQPQLPRLSPHLKDAVYSHPGNGEMAQAAQAYLDISIRQWMLQFPGVEKHPQLTNWINKITSYERLAIFFDLYEMEETSIRLPVDANPSGRKSVRVHGQVFKAYMGAIVKEYGDSALYTFMGKLLKYYMNVIGADWVNWIRSVVAAGQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF01</accession>
    <name>M5GF01_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632751.1">
        <property type="nucleotide sequence ID" value="XM_040769717.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5GF01"/>
    <dbReference type="GeneID" id="63684779"/>
    <dbReference type="HOGENOM" id="CLU_056607_6_0_1"/>
    <dbReference type="OMA" id="HYLTIHA"/>
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    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="164" mass="18810" checksum="9C8BE9216FA6FDC7" modified="2013-05-29" version="1">MSALNTSLTERPQIEIIIADTEELLQQCLAVRFNVFSDEQGFPEDTEIDQYDAPQRSVHFLLRLLPSLLPIGTIRIVQNPRKLTRLAILSEYRNFSFGRALVERAHLWVKEADPGTGGERPYDVVCHSQIYAKRFYAKFGYVEEGDEFDEDGAPHQKMVARLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFM4</accession>
    <name>M5GFM4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Galactose oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_48765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="341" mass="36440" checksum="0BC9578282936073" modified="2013-05-29" version="1">MSYKATWTRVPTPEGALPELTRSSHCIHAQDDTVSIFAGELKPREPVPSPIQYVSLSSGSLSAIPSGTEGVEPSPRVGATWTQLGDALYLFGGRGGVDMNPLEPELWKFDLSKQVWEQVKDVPDGRSYHAAASTGGDLYIHAGCPASGRLSSLDIFNPCSGAWSSLGPAPGPPRGGTVLAPSVLDNKPVLLRFGGFGGPEFGELADLAVYDVASNSWSNIPQVVGKHWPQARSVHGFLALSGEREKAILFMGEGKPAPAHLGHAGAGNFLSDVWVLTYTAEGWGWEEAIAHEKPQGRGWLAFDLLAEDPGKWKAVISGGLNEKNERMGDLWVLEVVREPGI</sequence>
</entry>
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        <name evidence="1" type="ORF">DACRYDRAFT_20953</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFT5"/>
    <dbReference type="GeneID" id="63687225"/>
    <dbReference type="HOGENOM" id="CLU_162870_0_0_1"/>
    <dbReference type="OMA" id="WANVEND"/>
    <dbReference type="OrthoDB" id="2585179at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="106" mass="11740" checksum="6DD63A55EAB548C2" modified="2013-05-29" version="1">MSQSQSQPHPPTLDHSANVYLAITHNPSHALSGPLPVHLASREVALEHVGQVGALKDVQLYEMPRVEWDALGEEGRKEVMGKIKGMEGVTAVEEQVLRQRVKRDEL</sequence>
</entry>
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    <accession>M5GG01</accession>
    <name>M5GG01_DACPD</name>
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        <submittedName>
            <fullName evidence="5">DUF21-domain-containing protein</fullName>
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        <name evidence="5" type="ORF">DACRYDRAFT_48039</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG01"/>
    <dbReference type="STRING" id="1858805.M5GG01"/>
    <dbReference type="GeneID" id="63689862"/>
    <dbReference type="HOGENOM" id="CLU_011310_0_1_1"/>
    <dbReference type="OMA" id="YFIHAIW"/>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000053">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.12, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF90">
        <property type="entry name" value="CNNM TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067702" evidence="3">
        <location>
            <begin position="50"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="4">
        <location>
            <begin position="123"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="430" mass="46076" checksum="4592076AD68370DE" modified="2013-05-29" version="1" fragment="single">MVDNIRIAPLSCSSSPSNHGCRLHLHARGVPTLLALCLLLAFCVSSALASPLGAAQSSSHGVLSSPSNRLGTLGQLSSYYNGLSDSAHALVKRATGHDGCECNRSSREQAAVPSQYSSDISRVFTVFIASAVLIPVLVLLSGVFAGLTLGYMSLDETQLKVLAVSGTPKQQEYAKRIQPIRANGHLLLITLLIANMIVNETLPVLSTEALGGGIQAVVVSTVLIVIFSEIIPQSVCSRYGLVIGAVMAPYVRVLIWALFIVAWPVAKVLEFVLGPHHGIIYRRSELKELINMHAAAEHMGGDLKGDTVTIVGGALDLQEKVAADAMTPISKTFMLDIDTKLDYETLATIVHSGHSRVPVFHQIQVGDKKVTKIIGVLLVKQCVLLDPEDATPLREIPLNAVPSVPFDEPLQGILNRFQEGRSHMAIVSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG50</accession>
    <name>M5GG50_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_87113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631767.1">
        <property type="nucleotide sequence ID" value="XM_040776798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG50"/>
    <dbReference type="STRING" id="1858805.M5GG50"/>
    <dbReference type="GeneID" id="63691860"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_0_1"/>
    <dbReference type="OMA" id="PGAYVNW"/>
    <dbReference type="OrthoDB" id="300709at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF14">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="39135" checksum="965E2FBAE8D8F5EA" modified="2013-05-29" version="1">MSTLPKIVVIGGTGAQGVPAVQALSESGRFEVVVLTRNKSSESAQSLASLPHVSLFEGTYLKESDVWALFKDAYGAFVNTDGFVIGEKAEIFWGMRIFEIAVAQGVKHYVWGNLYYLTKLGHYYPKYRSGHMDAKARVAEWLLAQKLPNITVTLFTTCPYANMFWDGMFHPIKMEDGSFVFHSSIGNGHLPLIALEDVGTYVQWIFDNKSRADNLDLVAVTDIPDYPTIISAFEKVTGKKAHWVDLPYDEYAAIRQLKDDVPAAWAHGSGEYNDPAGMSLKANFSGWWQSFRDDTFGWDKVDTKLLDEINPGRIRSFEEWCRKVGYNGENRIVLKDRKDKSFWERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG66</accession>
    <name>M5GG66_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631847.1">
        <property type="nucleotide sequence ID" value="XM_040771965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG66"/>
    <dbReference type="STRING" id="1858805.M5GG66"/>
    <dbReference type="GeneID" id="63687027"/>
    <dbReference type="HOGENOM" id="CLU_316642_0_0_1"/>
    <dbReference type="OMA" id="QTPIWTG"/>
    <dbReference type="OrthoDB" id="2563978at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="614"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="685"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="725"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="833"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="907"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="921" mass="96093" checksum="2326EEE71866ED1D" modified="2013-05-29" version="1">MTRLWEKRQGSETDQPLPDYLSYSAYSTAANGERQYTVVLLPQTYYGPSIPLGTDGVYVYGGPTSPADNAAAAPTDPASILASVASQASAAVTALPETTDPAFLSTFSEASVRSTSLAEEITSAFSQLSIAEQASQSVESFFSEVSSSVSMQSTASTESTQSTASAQSVASVSMTSAIIASLSSRRESRSSTRSVESTASVVSRESTSSTASAASLTSLASAASVASVSSISRTSAIAQSTESTASAASVSSLSHISQSSQSVISTASASSSTPTAIAAGSTSFPTRNIIALAIGLFFALLLIALILICLFRWRQRRNRSLVPQQRIPAERSHSVHQSMFFGRGGPSDGRVNVQGTVFDLWTPEQRAARENAQQRRSVSSWAGRTLALITGTYGSRGSAGSGSGGSGRSRGTGSSRIGIARKVSRTAAEDGLLEEETPLVGHNSPPLSPPPFHSPPAAGGGGRVVPLPTVREPSFLSPVVPPFAAVRDSGSFSTPSAVHSANQSRLTLPLSMASRPESPGDGEHETAELLVARRVTRSPSPKMGRLSWFMRMGLIGGGGPSTSSQEGHASMTEVGPTAESEAEFAPPEMSEIRTEGGTSLKSWLEMGGNAHSFPQPPPLPPLPNQPHPRQPTSLSTPQNGARPISTISTNSVYHDALSDLPPTSSRPGTPSYTAIPAPPAPSTPPRRRPVPFVSHHRIIASGSLPGSRTDLLDSPVPSPLRRSFNAGTGSPPSAWSKQPYSPDLEDELQPPPATAWRNSRGSEEMASPIDLGPSAERKEEPHRSGGIKRFTFGYPILTDAPQPPQRVRDGEHGPFHSLPAGAAPPKVRDSMTHFDTLSSRGAASFDNPSLTADTSFNASTPTTTTPRSSLAPSHKGVTLRGLGLEDPVPMAFSACGKPKTRAGRPATPSNTSGTRVDSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGU4</accession>
    <name>M5GGU4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_60648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632987.1">
        <property type="nucleotide sequence ID" value="XM_040775639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGU4"/>
    <dbReference type="STRING" id="1858805.M5GGU4"/>
    <dbReference type="GeneID" id="63690701"/>
    <dbReference type="HOGENOM" id="CLU_015848_1_0_1"/>
    <dbReference type="OMA" id="INISQNW"/>
    <dbReference type="OrthoDB" id="3365211at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="391" mass="44152" checksum="486E0097702681C4" modified="2013-05-29" version="1">MEQEEEEHHHDEVVEHLDCIGECVSTISHLANAANTILIPPIFSSTRKPVVALPQISLLPSDSQAQLLPEHDQADRAEKGMVIGIVPGEARPDELDLHVEHVLRKRDQAKRALRGLWAFLKTPMGILTAIYGFLVAFWGAAIVLFLLHWINLHNDYYQKLWIEITCQVENGLFTITGVGLIPWRVIDTYRIVRITHYKILSRKIRKQRGMKALNDENDIPDPENGALTEEAVLPEAQQKALRYQQEKFMKSQTWYRPHETETHRAFSITTALWICLLIDGNSIFQCMLCGTMWGLNMYNRPAWTTGSLVPLSFLCGIAAAVLIWKGGDRTKKVEEVEGKFRDALGVPEKEQCVKKSSSLMRLFTKGSNSARQEANSAQQVAQCDAGPSTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGZ0</accession>
    <name>M5GGZ0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein serine/threonine phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_44563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633217.1">
        <property type="nucleotide sequence ID" value="XM_040774588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGZ0"/>
    <dbReference type="STRING" id="1858805.M5GGZ0"/>
    <dbReference type="GeneID" id="63689650"/>
    <dbReference type="HOGENOM" id="CLU_021928_3_1_1"/>
    <dbReference type="OMA" id="GEQAMAP"/>
    <dbReference type="OrthoDB" id="420076at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="483" mass="53388" checksum="A8B3CB3F38A68485" modified="2013-05-29" version="1">MFRAWVRIDSKTREFRSFPLLPHSAVHELLNAHVRSSSLVLRGGKKWSWNVAQVSSNEPCEDGHAEMIISRDEPSAKETGKDKGEMLYFAVMDGHAGPWTSELLQKTLIPTVALEMDALMKGLPSPLLPPKSTFLNISPLLPSFLRTDGTAQPALVEQALRRAYTQLDRTIVSSALALLDLPKDKRPAVVAPFLRPGLSGSCALLSVLDTQHEEVHLALVGDCRAVAGYWDEGGKRWVCEVLTEDQTAKAVKEVERLKKEHPGEEEMVARNGRVLGGLEPSRAFGDARYKWTKDQQDRINRELISPPDVLRTPPAFQTPPYVTADPVVTHRPFRIPLTTTGGNPSVQDKIPTAQLRFLILATDGLWDALSPMEAVTIASTHLSQTHAGTFPQSTSPPIQGAAGVDGKGPGMHEPDKSAETWVYDQRDTPAVCLIRNALGSTPDQVRRMLSLRAPYSRRERDDMTVSVIWWEEGKDEEVAKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH32</accession>
    <name>M5GH32_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TFIID-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_74026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SPT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633427.1">
        <property type="nucleotide sequence ID" value="XM_040776044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH32"/>
    <dbReference type="STRING" id="1858805.M5GH32"/>
    <dbReference type="GeneID" id="63691106"/>
    <dbReference type="HOGENOM" id="CLU_038706_2_0_1"/>
    <dbReference type="OMA" id="QFMFNEQ"/>
    <dbReference type="OrthoDB" id="66982at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22926">
        <property type="entry name" value="HFD_SPT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000023">
        <property type="entry name" value="transcription initiation protein SPT3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF16">
        <property type="entry name" value="TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="348" mass="39901" checksum="B006280DCCE3C2B7" modified="2013-05-29" version="1">MSKAKVKDGDIGKEYKYQQEIAQMLFVFGEVPEPLPETTQLVEDIVRGQVIEIVILARHLAVKRGARHLTAEDLMFLIRGDRGKVNRLRTYLSWKEVRREAKEASKDSGGNMEEEALEENAADLTTKSTKMTVKLPWEISTIYSDFLKHTLDYKEDYKDDEDGQEATEDMNVRLKDADEATRKMTREEYVHYSECRQASFTFRKSKRFREFINFSAYSDIKPNDDIIDILGFLAYEMVRSLCIGGLEIKRILEEAQLQTTGLKRKLASSDESPNKKARLSGEQDDEGPGLPPSVQSSLFMRPPEARRPLRSAHIQEAFARMQRDATHLKSAGMQNWRGGLVRTKITLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNV5</accession>
    <name>M5FNV5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624868.1">
        <property type="nucleotide sequence ID" value="XM_040773893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNV5"/>
    <dbReference type="STRING" id="1858805.M5FNV5"/>
    <dbReference type="GeneID" id="63688955"/>
    <dbReference type="HOGENOM" id="CLU_006462_1_2_1"/>
    <dbReference type="OMA" id="PNGEKWA"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000064">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000004">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000087">
        <property type="entry name" value="Oligo-1,6-glucosidase IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF179">
        <property type="entry name" value="NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="5">
        <location>
            <begin position="16"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="583" mass="67288" checksum="4F939248153DDD6B" modified="2013-05-29" version="1">MESTVPKWWKEATIYQIYPASFKDSNGDGLGDIPGIISKLDYLKALGVNVLWICPFYKSPQYDMGYDISDYQDVHAPYGTKADIDALISGVHERGMKVIFDLVVNHTSHEHAWFQESRSSKQSPKRDWYIWKPAKMVDGKRAPPNNWRSNFGGSVWQWDEHTQEYYLHYFAPQQPDLNWENPEVRKAVYATAVNYWLDKGVNGFRIDTVNMYSKWLDFPDADIVDPSTPWQPADKFYSNGPRLHEFLKEMHRECFGRYDVVSIGECPNTPNFHDVLPFVSTKEKELDMVIQFDLASMDHGGGELRLWHRDWSLRLFKAITEDAQKLAIPEHDGWCTTYLENHDQARSVSRFANDDPKYRVAGAKMLATYLLTLSGTPIIFQGEELGMVNMPPSWDVDKEYKDLNTIDYMVELRRMAGSDKGMLEKGIYGAQRTARDHGRTPIQWDDSSQAGFSTAKDTWMRVNDSYKEINAATEEKDANSVLAFYRQLLTLRQEYKELFIYGMFELHESEDDNTITYIKRNGDQNALVLLNFTNQDQSFVIPSTFKGQPELLLSNLPKAGKHVLRPYEARIYVNKGKRVVNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNY4</accession>
    <name>M5FNY4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_118834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624958.1">
        <property type="nucleotide sequence ID" value="XM_040770666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNY4"/>
    <dbReference type="STRING" id="1858805.M5FNY4"/>
    <dbReference type="GeneID" id="63685728"/>
    <dbReference type="HOGENOM" id="CLU_266370_0_0_1"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="219"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="595"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="674"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="464"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1228"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1244" mass="135444" checksum="EB6F20CC67E29709" modified="2013-05-29" version="1">MAHSGARKSDPRVSSLDVHIVPRKPPVSIWDMPPDGTAPHSAPRPQQVVNRKKSTREIVAQFEAREAASSGGTPNKPHYQSERAPQTTPRRQRLPGDGLGVPYTSMPRVSSNLTPPVRPHSTGLTPPRPPEEYSPPQKDRSPLRDSLRNLFAIFKKGKSPAGKEDEVVAYQRDKEVHRDTWHGDTSESAARRTVAGSMQNTPEKELPPVTPEQRKLGPAPLRSGLVYYLTVEKQWTKRQISLEPPFLFMTDPVLATPSLAMRLETLTSVHSLPRSSALTLPPIRQKDFPEEPYVFELEFEEGNRIEIFALESASTRSSWVSVFWDAVLSMQPGPSMPPPSKQDDDPFLSPSLSDPMTHHPPLRVMNGPIPASPNSNTLPSPLPMARGDSIDNVGQMAGHTSAPGSGSKLRQSSLPHDALGLTSPNSIGLVIDAPVPTGPSPRPTSRPLPSLPTDQPPSPERVQPNPTIPDVTPVPVDEQGADIIRFPSAFSRRSRTTHGSPMSHALFSPQTEPDTTPTSPASSPPPKHVLSPAADIESTETRDAIRLSSIRSPSPTVSRRTSFATKNNSPRSPSIQTLSQLSVVRMRLAKLEVGEARVVPTSPTQPQGASSPKPRPPQSPPKPVQARQPDTPKTVTPKSSILTPNRRLSNMSFHTPPLTVKKRGTILLSRFPLPSSIGEVSSGGEESSAESDIGRAPPSNATRSSPTRRSQLHVVYESHRDSSASGQTYFTTARSSQHPEGYPVEWPDSSTDSGSWSGEGPRKDSGSSVATDRSSIVATPVDLPPQLDLEPVIAMLEPLPAHYSNLSEKMDGVRNGLGNVAGDVQKALMGIAELRTDIATTAPPEKATSALDEEAWQHVRRQLSELILLVSESVAGKGITKPESQEAENVQTMRNLGKRGNDASVVDDGAPELMDTEKPVIAEAVPNGLPKEELVASLEPLLEQQKHLHLQQTDTIRYLNELNPWLQKLALTAEKGDEVPAELQRIAKALGIERPKPQDGEEVAKEGPSFVTHVIDKLDGIRAIVDANQQSREAMNAVLKTLAEQRQEQEKLLRSVAAELSNDIRGERLRFVDAMKEATTLNVQVHLEEFKKQLNHEVFRMTQDVGHLRDDKMKLEQAIAELFAIKAKHGDHLYQMQQAAHQAQQASMQTQVSQPKVAPPPPVQQFLHPQHVPGMMYNLPGGYASIPSQQQQPVRHSIPPANARINMPPPLAVQQPIRQGAHASRPLPSTGGRTAAAGGPRSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP08</accession>
    <name>M5FP08_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623586.1">
        <property type="nucleotide sequence ID" value="XM_040769432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP08"/>
    <dbReference type="GeneID" id="63684494"/>
    <dbReference type="HOGENOM" id="CLU_461520_0_0_1"/>
    <dbReference type="OrthoDB" id="10676744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="591" mass="62263" checksum="9F43273A17D7B544" modified="2013-05-29" version="1">MTTTPPFPFSPTPPPSTDLPDPPSLLLHPITPISPHRTSPSSPQGPTPTNPPPPALSQRPMTPREPTSTPSSSSSSISSPLTIPPVSTLTTLRPLGGRRRSSLRPGFWIPQGSLLRNESKDPSLPGSGAQTPMSADSLKIRDPAAMSVSSDSRAGSDWGGDGGDQDQDQDQEDVFGFGERETEGMSLDEQETLRAAGREERRKLEEIFGHPREGEGEPMSPDISSSSHPRLPYLARVTRLLTLETSPMPEIESEAALQRLMSSASLPPTPLSSVFRKSHSGVHNRFPESAVLEESESSESSDEEEMEMAKAAVVDELGLGLGLGLGVGANATGGSGTSASATSSTSLPLPAISTGTGTGAIPIPSAEEDFPDDISMSEGSIWGMRASPILERAMWARSGGMDLDVPLQNLPSPYRLTPPPYTRKRKRSPSPSLSTQSQPPTQNQTQNQQQKETQTQPIPIKRPRLSHLSTPTNTPLTPHSLLPPFLPSSPTTTTTTTAAAAAANNNSNSATNSTTGSTTSTPGPLRPLALNGVGAVANSSPRWARAGLGGGLGLGLGLGLGGRGKELGEKDRERERELEAGEGVRRLSLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP38</accession>
    <name>M5FP38_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623686.1">
        <property type="nucleotide sequence ID" value="XM_040774179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP38"/>
    <dbReference type="GeneID" id="63689241"/>
    <dbReference type="HOGENOM" id="CLU_2170987_0_0_1"/>
    <dbReference type="OrthoDB" id="10463231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12250" checksum="61707E67AE179849" modified="2013-05-29" version="1">MPCQVADDHPAVLQLIAGQCPNLRSLIWDWPIASRNLPTAVTLAELANAAPTLRQLAIPANLTFAHRCPTTAHKGLEHLMLTSDTVYIEEERAHEWLERLYPNADISDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPG0</accession>
    <name>M5FPG0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_91956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623946.1">
        <property type="nucleotide sequence ID" value="XM_040777033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPG0"/>
    <dbReference type="GeneID" id="63692095"/>
    <dbReference type="HOGENOM" id="CLU_2589702_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="80" mass="9416" checksum="7DB69168BBF11E5B" modified="2013-05-29" version="1">MREIRTNSRDSKVECDRGSPRFCHHHRDYKYSCPAYRRSDNSPMGGNWHRRNKAGGDGSKDTMRSFHDESMDRHLAAHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPL8</accession>
    <name>M5FPL8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase I associated factor A49-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_25276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624056.1">
        <property type="nucleotide sequence ID" value="XM_040774097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPL8"/>
    <dbReference type="STRING" id="1858805.M5FPL8"/>
    <dbReference type="GeneID" id="63689159"/>
    <dbReference type="HOGENOM" id="CLU_034953_2_1_1"/>
    <dbReference type="OMA" id="DVYPFDE"/>
    <dbReference type="OrthoDB" id="532500at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="410" mass="45373" checksum="1C8B4B7404F727EE" modified="2013-05-29" version="1">MVSVVNANSSTHSRGAIVGSFPALVPASSTTFKCYHEPASHESRAVAASSEKSILFGRSTEIDFLSVNQDAAAINSGSFSEYMVAVYDQPANKLVIQPAPLYIMSREVKQKQVSTIDRSIGRRVQARNALGQTFGSKRSKAAIQAAERNRVDVAAMKGIAHHLQEDIRMNTRALPNISEQEAIYHNRPGPSPNMEANDPAGVYSINSVVPDSELKACPTRELVAAQSNDERTNILPYNRSTWINQRLILAGQESKISKLHLRLLFHISCMLCFRQATMNGGDMDKMNGRMSRIPSLVQEGLRARYSEPSRLSKTSRVTSEMDVKLLAHMFVLCLIVDNFAADVGTLASDLHLPPARVMKIFRAIGCKVEIPNVDDRTRLGLPKEAHLARRAFLRVPLDFPKPRRGRTQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPN4</accession>
    <name>M5FPN4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_59476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624081.1">
        <property type="nucleotide sequence ID" value="XM_040775564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPN4"/>
    <dbReference type="STRING" id="1858805.M5FPN4"/>
    <dbReference type="GeneID" id="63690626"/>
    <dbReference type="HOGENOM" id="CLU_1081917_0_0_1"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="29309" checksum="7525669D9F51F2EE" modified="2013-05-29" version="1">MRAHSERCSSRCKHHLFRSTSYLYQPSLSAKREHRPLRAVRKLVHLLYASHLRWKPVGAQAALPDYLAEAPSVAKPDIILVKLRRGQELNIEMHCVKSCGRDHAKYSPVATATSRLLPYVRIFKSIPEQLQAKFTQSFSPGVIGSRRNKQWEWEVFVKDARKDTMSRNVFLYPEFEGAVKLTRVRDRFLFTVESAGQMAPNAILPEAIAVFTRKLRTVSKALDELMHEDVEPEVQEGGWSLALSVGRDGCTNTILCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQF7</accession>
    <name>M5FQF7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626018.1">
        <property type="nucleotide sequence ID" value="XM_040769051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQF7"/>
    <dbReference type="STRING" id="1858805.M5FQF7"/>
    <dbReference type="GeneID" id="63684113"/>
    <dbReference type="HOGENOM" id="CLU_1767991_0_0_1"/>
    <dbReference type="OrthoDB" id="10510344at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="16804" checksum="D728CC8B826DD5B9" modified="2013-05-29" version="1">MDILCTHVPAVTLSLTSFDQWLTIQEQLAGHWNKTDPTFANDYQAMQQYFASITSESNGWMWDGRRCGDSEFVFDLATRLRNIVVEQVDTAVNRPTQFNRRGEMVCYFAAFAIVSLIQRFVVCAHGTMGHQQIESLLAKRFSKVDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQU3</accession>
    <name>M5FQU3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_72456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624047.1">
        <property type="nucleotide sequence ID" value="XM_040775969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQU3"/>
    <dbReference type="STRING" id="1858805.M5FQU3"/>
    <dbReference type="GeneID" id="63691031"/>
    <dbReference type="HOGENOM" id="CLU_009961_0_0_1"/>
    <dbReference type="OMA" id="VISCRKC"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="85"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT97149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="435" mass="49151" checksum="F08E6364CAFA5A07" modified="2013-05-29" version="1" fragment="single">MEQCNFFYAPTHLRLLRESQSEALPYTPKGRPTPSKIKGKGKATFDPDFESEREWLLLKIGADKLKADEELAEKLNEEEYVANGEGLECGCCFGEYAFDKMVQCAEGHLFCRDCARRQAEERLGLRQTDLLCMDQSDCNAPFPETEIARFLTEKSLNLYHRIKQGKEIEKAGLVGLESCPFCDYACVIENDEEKLFRCENEECLVISCRKCKKTDHLPKTCKEAEDDLRLNARHMVEEAMSNALMRKCPKCHHPFVKEGGCNKMTCNQCRTLSCYRCRRVIQGYDHFSERPGQPRYGEAGAVRDPSKCPLWDIDLEKLHADEVTAAARKAQEEILSTDDNIQIVKQDLEVDLPKPPPPPPGPGPGQPGYNGGVLPAEFMEHVLPMPIPQALPIVVPPPIHHAPFPAQHQYHYHAIVQYAPMHAVAVIHQGIQPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQZ5</accession>
    <name>M5FQZ5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_25318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624127.1">
        <property type="nucleotide sequence ID" value="XM_040774115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQZ5"/>
    <dbReference type="GeneID" id="63689177"/>
    <dbReference type="HOGENOM" id="CLU_1299672_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067209" evidence="2">
        <location>
            <begin position="21"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="212" mass="23890" checksum="B43CC2FA70162514" modified="2013-05-29" version="1">MHTHLVFLIALFATTIIVHALPLPLPSGVEEGCSQQAGFPCPPPTSFAAMQSRWRPGPSVVRPGVREAELKADLAWSEYGHAALHVEITQAQYDVAEEEQERLHQTVLPVLEHQLKQAKMDLADAHNKAKELEKKNLEHPDRIMGPKPHEEWKIAHVLHVKIHEQLTATQNDHHRRLKFAVKKAIKGDQLPHPVMLHRAVYGIHSTSTLETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR61</accession>
    <name>M5FR61_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625001.1">
        <property type="nucleotide sequence ID" value="XM_040770676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR61"/>
    <dbReference type="GeneID" id="63685738"/>
    <dbReference type="HOGENOM" id="CLU_1204729_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="24916" checksum="0072AC3E36B83FEB" modified="2013-05-29" version="1">MGPSHVRSYFASQATYTPLSCPAVKFKDWLCVIGLMIGGAAGLFVLFFIVVGCLACCFAIFEGCCRCCGPRRRRPVVTLPRYTTRDPENPAVIPDQNPQVIPDQNPQVIPEENPEVVPDCPPPYLERAPPTAVPVPQPGAILLSVLPRPAVPAQTHHSIRSSASSTRMTISTTPDAVPPSSSRISQPPRAHPSSHRVPSSNVQSHHTPSSQRTRLVVVRSQHTSVTLTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRP2</accession>
    <name>M5FRP2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_111718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624572.1">
        <property type="nucleotide sequence ID" value="XM_040769282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRP2"/>
    <dbReference type="STRING" id="1858805.M5FRP2"/>
    <dbReference type="GeneID" id="63684344"/>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_1"/>
    <dbReference type="OMA" id="MVPGFKY"/>
    <dbReference type="OrthoDB" id="10260828at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF79">
        <property type="entry name" value="ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="505" mass="54852" checksum="CABC21D8516AA72C" modified="2013-05-29" version="1">MYRQSALAAYRSRALTSTLARLSVRASSSSSGPCTKYTDVTHPEDPASLDPAIQRQLHRLESCTANTYARPPLIFTSGRGSHLFTSHPTREYLDFSAGIAVNALGHSDSGFIQVMADQVGSLAHASNVYWNEWVGELASLLVGLTRKEGGLGYAPDDSYTFYQRDSGPHLFSRTYTEPEPEDLPAPSPTGAKVFISNSGTEANEGALKFARKYGKELWARKTGKPWEESTKTRFLCFENAFHGRSMGALSATTNPKYQKPFGPLVPGFDMGKLNDMSSVKFITEDHCGVILEPIQGEGGIFECDIAWLKAIRKRCDEVGAVLIYDEIQCGLYRTGTMWAHSRYPTTAHPNVITMAKALGNGYPIGAILVKDEIAKAVTVGSHGTTFGGNVLAARLAHYVLTRLSTPSFLEHLALVTTTLDTRLSSLAGYFPSVVSSVRGRGAIRGVGFHKPEDAAKLVKMARERGVLFLSAGKDAVRFVPSLNIALKDVEHAMDVLESCLAVMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSF7</accession>
    <name>M5FSF7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625012.1">
        <property type="nucleotide sequence ID" value="XM_040773767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSF7"/>
    <dbReference type="STRING" id="1858805.M5FSF7"/>
    <dbReference type="GeneID" id="63688829"/>
    <dbReference type="HOGENOM" id="CLU_059017_1_0_1"/>
    <dbReference type="OMA" id="NIMFATR"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34244" checksum="B0EA34FC3B197A72" modified="2013-05-29" version="1">MANSWTKSFSAGLGQINLSSVSSGASRIAKGFNNSVQATRERLGQISPDDITELPAEYKELESRVDALRTTHLALLKITQAYGTETYDYPTQISESVSELSQSVAHNLTAFAATNLKGTNIPAPHVTPAVKVPPKTLNHALSRAAGVGAAVEGPDERLGKALKIYAEVNEKIGDARLQQDHTIRELFLTPWQATLSTSLTVAMKARAAVKQSRLELDAAKQGYYRMKNASPQRQEQARLEVENAEDDLVQKTEVAITLMKTLLDNPEPLKNLNELVKAQLVFHSTAAEALQGIQGDIEELTVAAEGDYRKSRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FST6</accession>
    <name>M5FST6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625227.1">
        <property type="nucleotide sequence ID" value="XM_040773668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FST6"/>
    <dbReference type="GeneID" id="63688730"/>
    <dbReference type="HOGENOM" id="CLU_2386093_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="94" mass="10675" checksum="24AB510EF0DEA6FB" modified="2013-05-29" version="1">MDEEIVYSASIQDQLILTMLIKLAGRGQTLVDRGAVSATIHCMPRKSLKSDLEYTTVSFFREDDSFITKVHVLPDARIFRDEDELSSDVKLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSX1</accession>
    <name>M5FSX1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625956.1">
        <property type="nucleotide sequence ID" value="XM_040773563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSX1"/>
    <dbReference type="STRING" id="1858805.M5FSX1"/>
    <dbReference type="GeneID" id="63688625"/>
    <dbReference type="HOGENOM" id="CLU_1079889_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067207" evidence="2">
        <location>
            <begin position="19"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="27205" checksum="8B6B2CA76F68BD83" modified="2013-05-29" version="1" fragment="single">MQITSVVILAALAASIAANPLPEPQGGLSGAPIRRIERKAERRGGALGERKEENFLRANRPRDLELMKSNLEIRSPTLEFDLEARQEVEEPASAAATPATPHAQKGAGKHAGRKARGGKRGRRTRGGKRGRRTRSGRGAHGRGGSRRGGRKSHKKVVEEATSPAPGAEATSPVPDAAPVTPGSAPAARSFDDDFELEVRSPQGRRGGGGRGGRGSMGRGGKGRGRGGKGRGSRKMQPQQQSESEEAPPSARDFSLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSX2</accession>
    <name>M5FSX2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-ribosomal peptide synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_57397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625307.1">
        <property type="nucleotide sequence ID" value="XM_040775438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSX2"/>
    <dbReference type="GeneID" id="63690500"/>
    <dbReference type="HOGENOM" id="CLU_005562_0_1_1"/>
    <dbReference type="OMA" id="TWIVLPW"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47799" checksum="BEAB06CBFDF8946F" modified="2013-05-29" version="1">MVRRKLCTIVAIFNAFAIFFASIGRFGYATSHPGAFIVGNLCIAVLVRNECFLRSLFLILNTLFAKWSPLWWRLSISSMLQHLGGIHSGCASSGLAWMIWRTVQLVQLSGWSGPAANAFGIITCTCLGITFFAGWPVVRNRAHNVFERWHRFLGWTSLVMTWVFSIVATQFNTTTRQWEYNPMAVPHAQEFWFVIGMSVWIVLPWTMTRRVPIEIEIVSPSSTTAVIKFRRGMQQGLLGRISHHAVWEYHLFGLISVSPKADCHYMICGVQGDFTRSLVEKRPKYIWTRELKIPHVSNTSRLYQRGIRVCTGTGIGSGLSTIMQSPNWFLIWIGSDFRNTFGDTIVDLMEQNVGEERRIIWDSKARKSRPDIMKLIKEAYDSWGAQVVFITSNYQGNMEMMEGCKRLGMPCYGTLWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUT9</accession>
    <name>M5FUT9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_17463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626177.1">
        <property type="nucleotide sequence ID" value="XM_040771287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUT9"/>
    <dbReference type="STRING" id="1858805.M5FUT9"/>
    <dbReference type="GeneID" id="63686349"/>
    <dbReference type="HOGENOM" id="CLU_413888_0_0_1"/>
    <dbReference type="OrthoDB" id="10652347at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="663" mass="71048" checksum="3ED5703A8811D80D" modified="2013-05-29" version="1">MSISSITAFDDSLHYLTNVNIFDALAQKSTRNPWDTWINSMDDHADRPARHLVDGSESDRSSVPLPSDQGSDTSINDAGSSRRSSVVSHMSVESVRLAHTSAESGQLDHISAEAGHLARNTRHSGYSAGSELSASTGNWGSPVISGNSETSPSSPISSRITDSGNPARNSTSRLSAAVLDPDCNHDDSEYWASTEGSDASAPSPGSLVSSDHRMSMLPGESIIPTRVAEHTVADGVNNGGIGSMTGAMPEDELQRLTRATALAPDGTLDDWDQALFAQYLDAQVLETSSSSLSPNELPPQLPIPRVFLPPWLSQSSFPNTIPALQMTPPKLPFLPVPRDRHGRRMGMSVVLGGPNIATAVAPHQLVLPAPSQFPPTLAALLGQSPLSSSPFSPPSFAPSPAASSWLPGSDSSSPAAMEPMSEFLVYRTIPHLMNGRAPHPINGRTPHISSPLSTSDSNSVLSAGDRGSPTFYREPYSARKKGNERRAGRTRRTCKSNGHEVTFDTGELVYFLCGLPSSPSCLGKACAYAFTDRGALDRHVTNSHAMREWEELWTDQVTDPGKLVFGGFMAPKGQGCDCNICGKRLSRPDAARRHEALHTESDRKAAARGKRTATSKRKTPVQLAKWFTLEDSHLRVDSTVGKEKGNVLRPYTFTGLGRGMGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV64</accession>
    <name>M5FV64_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyltransferase family 18 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_117734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626392.1">
        <property type="nucleotide sequence ID" value="XM_040770443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV64"/>
    <dbReference type="STRING" id="1858805.M5FV64"/>
    <dbReference type="GeneID" id="63685505"/>
    <dbReference type="HOGENOM" id="CLU_337070_0_0_1"/>
    <dbReference type="OrthoDB" id="2113294at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030144">
        <property type="term" value="F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026116">
        <property type="entry name" value="GT18_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15024">
        <property type="entry name" value="Glyco_transf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase family 18 catalytic" evidence="1">
        <location>
            <begin position="687"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="845" mass="95215" checksum="34221C68ADE9B837" modified="2013-05-29" version="1">MLPLPRLRSLLLILLLALLILIPTLLYLEWPPLLSLSPHLRALSQPIEFPWRTKQQEYDYPDPDREPGEDDACPFDPFLAPGMLYFGTSANETRWVPFPLSESAYTPGSLGLLEDLDQEQQLTEREMQELGTAERLMLGMAEGGGEWARGKGVLFVGSSHDRNNVQNFCDAVGGVHTSWGMHTGGFCKLARLEFTIVYWFMYGIPDSESYDWHAPNEPRPITPARRVKEVFLPQMEQVGLRGWTPDLVVVSSLFWDTDHLFDKYFTHMGIKRPWEQGLTWQEVRPSVPSLRSLLPPSCSSANPLPQVRWHQTSSSSLLSLLRSTYPPLTPLMYRSRHIRASNDKGQMLRVQQLDMAWRAVARRAGVRVFDWGGRLEGYTPYYDGNQHFPNGPATWLFGEPGQRSATGHNLHMLALLQRVLLLAGGSTLLLLSIFFRPLTLSTSLPLPPPRHRPDSAHFESLFPPLPGSAAEERTRAENARTVRALVGCLARGDCGENQSSVVILASPQFGPEIEAHNNPDGAWALSVQDALDQLGYTYLWFPSLSSALPTYVLFPDLVRLVLASPPDVSHCFASQDCIKSPSNPLGPPIWKLFAFSPQGSTDTPLGAEWSLSPEEYGTGARVLGYSIEDSCRKVPYVPPSAREAHVYILGDRLSYWYHRDFAWEDGVLWGLRDAFFLEVSLVGGLVNDTRWETYWPPYMNNYGLMAKEDYYSLLSHSQVLVGSGIPANSPAAYEALCFGVPFINPILRWDEKRPFHRESWVTQHDALKHLEPPFVYHVRKMDGEGLIKAVRAARGSPIGRYIPANMHQSALRQRVSDLVETDWRSKAQEVLSRRVAAFESPLFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVB1</accession>
    <name>M5FVB1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626452.1">
        <property type="nucleotide sequence ID" value="XM_040773332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVB1"/>
    <dbReference type="GeneID" id="63688394"/>
    <dbReference type="HOGENOM" id="CLU_1938090_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="130" mass="14500" checksum="448F246E0CB9D679" modified="2013-05-29" version="1">MVRHLHPQPDSPQSTICAAGSTCPLPVMVMMLYLAHQFLQSAMDPAALVHEMERCFPILTSAYQWTDCPSSPDSTPQSYQSQSLMQFTGDLVPVLHLSLSHNMFTQSMWSRYIPPDCFGNVETTSGAYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW15</accession>
    <name>M5FW15_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HOOK-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_24950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624454.1">
        <property type="nucleotide sequence ID" value="XM_040773930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW15"/>
    <dbReference type="STRING" id="1858805.M5FW15"/>
    <dbReference type="GeneID" id="63688992"/>
    <dbReference type="HOGENOM" id="CLU_017588_0_0_1"/>
    <dbReference type="OMA" id="DAKYRKC"/>
    <dbReference type="OrthoDB" id="49395at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008636">
        <property type="entry name" value="Hook_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043936">
        <property type="entry name" value="HOOK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05622">
        <property type="entry name" value="HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19047">
        <property type="entry name" value="HOOK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HOOK N-terminal" evidence="7">
        <location>
            <begin position="38"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Hook C-terminal" evidence="6">
        <location>
            <begin position="290"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="840"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="230"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="517"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="659"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="840"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="913" mass="102815" checksum="6F6C70F2ECFCB0FD" modified="2013-05-29" version="1" fragment="single">MADVELSHSAQSVPDPAPVAEDAEAEEADLPPQDAELSAFLAWLSLLSLSPPNTPSPTLTSLTDGTLLLSLLSRASTTHFPLPARQLSPSDPWPLRLTQLKALYRRVAQWYAERSDTLLGLGEKDGSGEEWVPSLQLLVDTSSPSPSLAEREREVLKLLRLVVGVAVQGEEKEEAVGAIRELRTDQQTLMMRAIERVMAAFPPRAEGAAEDADTSMMTDDDHYYSLQSARSRLQSENTQLHSALQALQVQVDQLQTQASDLQAEKDDALQTARELRAQAEERRGREVEAGLRGEIERLKDTLRTSEDTISSLEGQVQRQERDLSDISRRALELQEKADSAGRLKDQVDELRHAAERAQKNENVIEKYKRKLEETADLRRQVKTLTEQNTQLVNTNSQLEAQSSKSANVKPLLDAYKQQISELESKASARAAEVEGLRVKLEEERRARVELDRLREQERREAEGYAERVRELESGMRVKLREGWGGEEPLSPGLGLGEAHETEGEALTLDDALSGTTMTDLKLRIRALERELLDAQQENGTASRVLVLENLLEDANRLKARYEKEYLAAHREALVLRREVEEIRAGKGGAESGEMVIAVRKRLNELVEELDGTKKSLEEKGVELDSVLRELTVAKSDLNLVNKDQLEILASLRASVSSDNAGLSAELDRLKQVERELREKNRMQMEQVNGLLMEKIELQGEGIGQREAMLKRERDIGDLRASIAGKDLPEETKRRLIDLADENARLKEEIKLERQKLVKARQFIKDQDELFSKQHAGKVDPGTFTEAEKAYKSQIGTLEDKIALLTRTIKENAAAYDREKQQLQSSFRVLGSQQRQTQLRTAASRTGTRLQPQSWLAQQREHTDDGQPLPLRVERLVIPRPLRMGWNLTTHSMPARNVGRAIEYLAYTYTRHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWB2</accession>
    <name>M5FWB2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_55301</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626872.1">
        <property type="nucleotide sequence ID" value="XM_040775312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWB2"/>
    <dbReference type="STRING" id="1858805.M5FWB2"/>
    <dbReference type="GeneID" id="63690374"/>
    <dbReference type="HOGENOM" id="CLU_005417_3_2_1"/>
    <dbReference type="OMA" id="WILNTRI"/>
    <dbReference type="OrthoDB" id="4096at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057644">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23769">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="300"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="WD repeat-containing protein 75 second beta-propeller" evidence="9">
        <location>
            <begin position="405"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="637" mass="69165" checksum="457F351972F76427" modified="2013-05-29" version="1" fragment="single">MVGVEDTDGAEKVKEKKNVKGKAVEREGKKWDWVSLLDAKTSDHPAVFTKDSRFFFLPSGTSVNIHSAATGDVVSTLTLPTPTPGKASKHRITSLALNPSNAFQLLVSHLDGSIRVWDFLDGVLLRTVELESGITHMCVSEKLKNQVLVAVNEVGKKKGDSDGMSVSDYSNRFMLKNFPAPAKPQYVLYRVSLTTQAKTYIGKLPPASHLALSQSAQHLVASSGSTCYVFTVPAEGKASVMKCLSTDRITSLAFHPEEEWFAAGDEIGTIKFWYCSESATGNTAKGQERASLPNASHLWHAHAVRSLSFTPNGAYLLSGGEEAVIVAWQLHSGRKEFVPRVGGPIRWLCVKNPVQGGEEEWVAGLADRTLVWVNAGNLKVSRSVARVKLDISATSSEVPPALPLAVHPATGNLLLPSSHPSFLQIYSHPTRSLLSELEVHPSNRVSKRNPDAPSLPAARVERVCVSPQGKWLATLDVRRGGEGEGIVSRLKVWRWDARRGAWALNTRVESPYGVGEVTGLAWMPDPQGSSSKTELGCLLATSGKDGLVKTWRTRVERGEEGEEEISWVNRSAFSYRAHVPHCCAFSPDGSLLAIGQGPCVTLWDPVTNVMQRVLAGQGAAIVEQVEFVSSEGRWLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWL3</accession>
    <name>M5FWL3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1771-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_100788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627671.1">
        <property type="nucleotide sequence ID" value="XM_040767491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWL3"/>
    <dbReference type="GeneID" id="63682553"/>
    <dbReference type="HOGENOM" id="CLU_583971_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067287" description="DUF1771-domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="51080" checksum="2D21611705B4B601" modified="2013-05-29" version="1">MIISKTVLLTWLFAAFIVSASPLLYLAPRGNWLEAGDAPALLGRAPPASGHPKSSMHASVSSTPLPAYSKKDPNPGNTPEKKSTSSVHDDTAYSKKGPNPGNTPEKSRGLIRDFFHKTFGKKSGQPTSPVHEDTDYLPAYSKEDPDPSPPYPGKKSKGIIRDFKTVLLTWLFAAFIVSASPLLYLAPRGNWLEAGDAPALLGRAPPASGHPKSSMHASVSSTPLPAYSKKDPNPGNTPEKKSTSSVHDDTAYSKKGPNPGNTPEKSRGLIRDFFHKTFGKKSGQPTSPVHEDTDYLPAYSKEDPDPSPPYPGKKSKGIIRDFFHKTFGEKASDRPWYTTHLKQLAKQHAEDGNHKLAADAHRALGDLHAKSAQDYHEQGDLEAAAQLREASKKSLQKAENADLEAKRNPAQQPISKKAEELQNQVTLGHSLEAVVEHQIKRPDYRGTTLDEAYFKKNFGKLSAAYHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWV6</accession>
    <name>M5FWV6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_22095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629355.1">
        <property type="nucleotide sequence ID" value="XM_040772672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWV6"/>
    <dbReference type="GeneID" id="63687734"/>
    <dbReference type="HOGENOM" id="CLU_141735_0_0_1"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="157" mass="16161" checksum="3908CCAED984A149" modified="2013-05-29" version="1">MSIKGAAFELDGNPSALASTALLYSLLLPALLPSSTMQSFVFVLALVASSMAYVLPRQSATLTCGTANLQCCNTLALASEPLIANALGLENLQIPGPDITVGLNCTTPPDDGTPVTAQCIGILSCCTSINIGVNSDISEDCTMTGIGTKRDVAYEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX70</accession>
    <name>M5FX70_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_67801</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627931.1">
        <property type="nucleotide sequence ID" value="XM_040775860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX70"/>
    <dbReference type="GeneID" id="63690922"/>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OMA" id="LTAHCIM"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF319">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="204"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="394" mass="42771" checksum="E3D62CEEE7492EE3" modified="2013-05-29" version="1">MTVAGSWFISSICFGYVNAFGVYQTYYVETLLPSYSASSIAWIGSLQTYFLFAMGLVTGPLFDHGYFWHMMIVGSVLYVGTLFAQAQVQKDSYYQVFLSQAVGQGIAMGIIFLPSMAVIGHHFQKRRALAMGLTVTGSSVGGIIFPILVNNVFNDRGYVWGVRAVGFFVLGACVLGNLLMRPRYPPRHTKPPTPSIFKLLRDPPYVVSIGGLFLTALGLFFVIFYIQLYTLTQGISENLSFYTLAILNAASVVGRTLPNILADRFGILQVMIPTVFLSGAIVFAMFGVKSVGAVVIFCIMYGFSSGAVVSLLAPLMAALSDHFWEMGMRMGFAFSLIGIAALIGTPIDGALIGNGPVFDWWKAEIFSGIVMLAGCALLVVAGYLLAKKRGLHFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX93</accession>
    <name>M5FX93_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624994.1">
        <property type="nucleotide sequence ID" value="XM_040769169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX93"/>
    <dbReference type="GeneID" id="63684231"/>
    <dbReference type="HOGENOM" id="CLU_2145772_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="112" mass="12127" checksum="0A30E9BBD3DD5F2E" modified="2013-05-29" version="1">MPPSLSGAQTLSPADSLPPLGSPLPSSHSSPNYPSPSASPSRILQQHVAKCKRHREELDAAAKRTKIEGCTFCSSGKHVGRALTLFGNVEKILRDGRECFEVEDVEEINEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXM8</accession>
    <name>M5FXM8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_54113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627442.1">
        <property type="nucleotide sequence ID" value="XM_040775232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXM8"/>
    <dbReference type="STRING" id="1858805.M5FXM8"/>
    <dbReference type="GeneID" id="63690294"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OMA" id="ILPTGWM"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08286">
        <property type="entry name" value="FDH_like_ADH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF4">
        <property type="entry name" value="NADP-DEPENDENT ISOPROPANOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="7"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="348" mass="36911" checksum="A751C240CBEA1386" modified="2013-05-29" version="1">MKALIYKSLKRVAIESRPIPRVTAATDAIVKLSRTTICGTDLHLIQGDVPTCQPGRILGHEGVGRVHEIGAGVNRYKPGDHVVISCISACGTCDYCRKGMCSHCTTGGWILGNTIDGTQAEYVRIPHADTSLHPIPEGADERALVMVSDIFPTGFECGVLNGKVQPGSTVAIVGAGPVGLAALITAQLYAPSTIIMLDQDENRLRVAKQLGATHTVNPATNANAADTVKSLTEGLGCDTVIEAVGIPQTFATCQDLVAPGGTIANVGVHGTKVDLHLENLWDRNIAITTRLVDATTAPMLLKLIKAGKLNPSQLITHDFAFKDIEKAYDTFHAAAQHDALKVVINFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN8</accession>
    <name>M5FXN8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628146.1">
        <property type="nucleotide sequence ID" value="XM_040772816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN8"/>
    <dbReference type="GeneID" id="63687878"/>
    <dbReference type="HOGENOM" id="CLU_1796410_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="144" mass="15532" checksum="A74B3DB100FACEE6" modified="2013-05-29" version="1">MPSVPTLPTTPPDSSPPITSSTLLRLHRHSNSLSGHGNAIELLPLTAGSSDEHLHAPAEPPTSTTSEYYDHRMELRLGERDVEGMEGFSREENIFMAGSFGAVVVLSVVSGLITLKVICGGREGNIWIYPCLTFSFATTDDHPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY34</accession>
    <name>M5FY34_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_42811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629870.1">
        <property type="nucleotide sequence ID" value="XM_040774524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY34"/>
    <dbReference type="STRING" id="1858805.M5FY34"/>
    <dbReference type="GeneID" id="63689586"/>
    <dbReference type="HOGENOM" id="CLU_2984468_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="58" mass="6365" checksum="7C3283F5BD7EE300" modified="2013-05-29" version="1" fragment="single">WHLNSTVTGDFLGSLPLVIGMKVMIIENIALQYKAVNGAEGTLTNIKYDITDGIRYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY38</accession>
    <name>M5FY38_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627597.1">
        <property type="nucleotide sequence ID" value="XM_040773082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY38"/>
    <dbReference type="GeneID" id="63688144"/>
    <dbReference type="HOGENOM" id="CLU_2339103_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="98" mass="11112" checksum="F1B0B62F4EA7E862" modified="2013-05-29" version="1" fragment="single">MPILLYRIQNLHIPRTRLRRALRQFPPAWWTLFLPLPFPINPRRLRTRLILRAGTLFFLLRSWVVLVVIALQGAGYWPSPSPSSTGTTAPGAPGMGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY73</accession>
    <name>M5FY73_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_16686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627652.1">
        <property type="nucleotide sequence ID" value="XM_040771219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY73"/>
    <dbReference type="GeneID" id="63686281"/>
    <dbReference type="HOGENOM" id="CLU_1204727_0_0_1"/>
    <dbReference type="OrthoDB" id="2959771at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="230" mass="26386" checksum="5BA800663E4997CF" modified="2013-05-29" version="1">MKYKVGNQMPCLSIGHKPDDQTLLWPDFSQDINTAPNWLLQIHAAMLVLEQERDHPGNVPKQYQEKWVMSAVLMELAHATWPHLKQVFLNQHNAEKDGGREQRKKKSLHMTQMCGAITDFCIKHNLDHIALPATLVYDDWVWEWYQSVHTRYMRKVAVNGKPGCRAGKHINLGHTSSLMLKVKPFNSMLDSNWLQTDLPRCPDCIHHPGLPAGLSLGIMQLIRPSIEPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYG5</accession>
    <name>M5FYG5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tf2-1-like SH3-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_53535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627797.1">
        <property type="nucleotide sequence ID" value="XM_040775180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYG5"/>
    <dbReference type="STRING" id="1858805.M5FYG5"/>
    <dbReference type="GeneID" id="63690242"/>
    <dbReference type="HOGENOM" id="CLU_132807_0_0_1"/>
    <dbReference type="OMA" id="WENYENC"/>
    <dbReference type="OrthoDB" id="3158924at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tf2-1-like SH3-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="149" mass="17385" checksum="25EDCFC4BDCE978D" modified="2013-05-29" version="1">MHNLAVPKNWAVKLLPRNIRPFHIRKVMDTDNCLLALSESMKKCGIHPTFHTSLIRPYIHSDDVLFPGRDPDTIYGNAPDGKQIIELIDDHHWRQCKLQFHFIWSDRDQSWESASKADQLTQLDEYLELQGMKTPEDLPKRDPQGQCHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYH9</accession>
    <name>M5FYH9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_57265</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625499.1">
        <property type="nucleotide sequence ID" value="XM_040775427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYH9"/>
    <dbReference type="STRING" id="1858805.M5FYH9"/>
    <dbReference type="GeneID" id="63690489"/>
    <dbReference type="HOGENOM" id="CLU_010811_3_0_1"/>
    <dbReference type="OMA" id="PYNYQYE"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000135">
        <property type="entry name" value="Related to KRE6-glucan synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF15">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="10">
        <location>
            <begin position="107"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="523" mass="58250" checksum="ACA645F5DD3A34CB" modified="2013-05-29" version="1">MYLWDAKDPDLDDALHNPDPEMDKRLDRRWTIASLRGWVNMTMLLVLILALLMLFIGYPAIYFFSQPKIVRSGFNLGGINSTGQVPDIPGTWQMIDPSTPSSAMQHTGFDGQQYDLVFSDEFEVDGRTFYPGDDPYWEAVNLNYWATVDYEWYDPSAITTKDGKLVITMTEELIHNLNWKSGMLQSWNKFCFTTGYVEVMVSLPGSGDVPGFWPGVWMMGNLGRAGYGASTEGVWPYTYAACDLGTYPNQTTKGGEPAITKTDGDQYNGNYLSFLPGQKLSACTCPGSDHPGPSVTTGRGAPEIDILEAQVNVWENQGSVSQSYQVAPFNDFYQFDNTTTTLYNSAPTTVYNGYRGGVYQQSVSAVTLVSNANYNNNQYGVFGVEFWSNPSNRGEGYVTWVADGRRTFNMPASAVGADPISEVSERLVSEEPMSMVINFGMSSGFQGQDFTRLQFPATFYVEYIRVYQRTSVSGNPDYQSCDPAAHPTLNYINSHLNAYMNPNLTTWDAAGYTFPRNSQFDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYK8</accession>
    <name>M5FYK8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_108298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627857.1">
        <property type="nucleotide sequence ID" value="XM_040768627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYK8"/>
    <dbReference type="STRING" id="1858805.M5FYK8"/>
    <dbReference type="GeneID" id="63683689"/>
    <dbReference type="HOGENOM" id="CLU_1586423_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU00960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="168" mass="18465" checksum="5985E20C8CFBD54D" modified="2013-05-29" version="1">MKKDRVEFVVVDEHAEARIDDIAHLLQEYPSLSHAKIIHLCAPSADFLNRRPGAKAGVAIEAVAPEMHTYIHGGLIARMAKPARTQKFLRILSRMWDARSGYTNGSTLRDGLRGNKISADMTSRSVAYAGNVLVAEDNPIARNLLVRQLQRHGSTVTAANNGEEAIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYM3</accession>
    <name>M5FYM3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF500-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_100545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627882.1">
        <property type="nucleotide sequence ID" value="XM_040767464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYM3"/>
    <dbReference type="STRING" id="1858805.M5FYM3"/>
    <dbReference type="GeneID" id="63682526"/>
    <dbReference type="HOGENOM" id="CLU_015320_2_2_1"/>
    <dbReference type="OMA" id="TQNDWWT"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11842">
        <property type="entry name" value="SH3_Ysc84p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="515"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="326"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="456"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="574" mass="62402" checksum="81CD5DE195F5580B" modified="2013-05-29" version="1" fragment="single">MPLIKLNSPIPVPLPKEVQKCAKILESFVDSSNNGLDGVIPRQVLQNAKGFAIFTVFKAGFVVSARAGSGVVIARLNDGSWSAPSAIGTAGMGFGGQAGAEVTDFLVVLNSRSAVRSFMSAGSLTLGGNMSIAVGPLGRNGEASGSLNTNGKLATMYSYSKTKGLFGGVSIEGSILVERQDANANAYRADVTAQQLLSGAVPPPYWAEPLIRALEACTGLPGGRKWINEDMDDWIASPNPYNPSRMGGGYEFGGIGTPPPDRHNRRRSLSSSLSRKSHEDEYFPEVPDHDFTAVSPRPGVTRRRSLFGSKGSRNNAYFNKQLEIDGYSVPNRGHDNDVDSKPSSESFGSSESSARGPHARERAGSLSRFCSLSLRPRSRSSRSTPGLPRDRDDDDPWNEEGYFLNEKDEGRRRSEGNEWDEWEPEPDPNYSYKIYKPRSRVDKAVVDEFDPYAPSKAYTTPSAHPPTSQLHPPPPVNDFSETDEATPFGDELELESKPRPTRQLSNKTDLKAPDLGLGKGIALYNFEAQQSGDLGFRRGDVIVITKKSQSTDDWWTGRIGGKAGMFPANYVEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G092</accession>
    <name>M5G092_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Delta-sterol C-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_21912</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629066.1">
        <property type="nucleotide sequence ID" value="XM_040772601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G092"/>
    <dbReference type="STRING" id="1858805.M5G092"/>
    <dbReference type="GeneID" id="63687663"/>
    <dbReference type="HOGENOM" id="CLU_039068_5_3_1"/>
    <dbReference type="OMA" id="AFNKAMH"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003838">
        <property type="term" value="F:sterol 24-C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000232">
        <property type="entry name" value="Sterol 24-C-methyltransferase erg6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="4">
        <location>
            <begin position="46"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="344" mass="39082" checksum="F53F211CD18DD5EC" modified="2013-05-29" version="1">MGKEGDVRSQGRMENYTSYWEKDSKTDTEAEKDHRLNNYTELINGYYDGATELYEYAWGKSFHFSRFYKGEGFYQSLARHEHYLAAQMGLRPGMRVLDVGCGVGGPAREIARFSDVKIVGINNNDFQLSRARKYTEEAQLSQQIRYQKGDFMKLEEIFGSNSFDAVYAIEATVHAPSFEGIYGEIMKVLKPGGIFGVYEWTMTDRYQPNNLAHKRIATDIEIGDGIPEMRTSADAREALKTVGFDILHEEDLADRPDPIPWYYPLEGDLSKAQTTWDYFTVWRSTWSGQIVTHSALWILELIGAVPKGTVEVGESLKRAGRGLVAGGQIKIFTPMLLFISRKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C5</accession>
    <name>M5G0C5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribokinase</fullName>
            <shortName evidence="9">RK</shortName>
            <ecNumber evidence="9">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_89278</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="9"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628492.1">
        <property type="nucleotide sequence ID" value="XM_040776902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0C5"/>
    <dbReference type="STRING" id="1858805.M5G0C5"/>
    <dbReference type="GeneID" id="63691964"/>
    <dbReference type="HOGENOM" id="CLU_027634_2_1_1"/>
    <dbReference type="OMA" id="DIVLIQQ"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="10">
        <location>
            <begin position="6"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="41"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="224"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU01595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="320" mass="34249" checksum="F4FA936512E17AF2" modified="2013-05-29" version="1">MAGTCLVRGSINIDEFFRVPHIAHAGETLSSTGELTRRAGGKGANQAAAIARAGGNVQLVGAVGTDGDWVKQQLSEAGVDVKGVHIHPEISTGRAIIQLTPEGTNHLALHPPSYHLAPPITHLLLQNEILQETTLEFLKYAKEKGIRTIYNPSPLLPKEEIAKFPWGMVDYLLLNEHEAAALADATAPHAHAHSLPPTSKAPQIATVLTRLQQPLFQHCTVILTLGGQGVVAHISKDEIYYLPAATLRGTVRDSTGAGDCFTGYFVEGLLSGREKEQDGWKGLLRRCVVAAGMCVERSGAMGSIPTAAEVDERLNELGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0E7</accession>
    <name>M5G0E7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT99306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626204.1">
        <property type="nucleotide sequence ID" value="XM_040773443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0E7"/>
    <dbReference type="STRING" id="1858805.M5G0E7"/>
    <dbReference type="GeneID" id="63688505"/>
    <dbReference type="HOGENOM" id="CLU_433462_0_0_1"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="3">
        <location>
            <begin position="92"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="631" mass="68493" checksum="EB84C16B9FE91E67" modified="2013-05-29" version="1">MGYSRSQSYSESQSQSQSQSFSMSQGNSQNLGDLDFDDMMADLEVPGIPQATDLMDFGGLGEITESYAEKAARWGIEDDGANEGLSDPADLRSISFQRSKGENRRFADEVGFLLEGLKASQPLAVRRSSALQFVENVLDHEFIRKLKVIDGIARSWNFLRQAGAGDGDHVVDGALFLFLALITKDIRNFDPLLPKIDDVVSAATKTLSISHEDDPLIGARVPKSERGLINTLKSLLRKAKIDTEDAAMSTRRLVSTSIKALAALMPTPLSLPILEPVIASLLQEIKTFTERLKSFTAGEPLEQEDADNGSSLVDLTHTDNCLRVLEAFTMRGNRYEHASAAMDIVRGQANELTQQLLSLSLGCQVLMGTANEKKAVTAATCLISALRVPVNLSSSDVFWCRAILSHPITLPGTIRIIIQSEREAAKTSPVGGRESVHDVLCLGLALLTNLVEQVPGARESVREITYNPSCPGKPACTFDCRCPKRISALRCLVELYERKTEEAESCVTDGQAIQGAEAAFVAGHCSVLLGILGLDNAANLKIIVKALPGKHRQEKIDQLLTAVKDFSEVQSGAKQALDTTKTHACEPGDMEEAEDMREREPADTTDDGSEDKSGMIISQIITMLEELRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0G9</accession>
    <name>M5G0G9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626224.1">
        <property type="nucleotide sequence ID" value="XM_040768986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0G9"/>
    <dbReference type="GeneID" id="63684048"/>
    <dbReference type="HOGENOM" id="CLU_131496_10_2_1"/>
    <dbReference type="OMA" id="PQMLEWI"/>
    <dbReference type="OrthoDB" id="10011777at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11302" checksum="3A7F29B24E72B5CB" modified="2013-05-29" version="1">MSSTPSLIKGRITVIGALTVKDGKLQELLGLLGAIKEHLHNESGTLHWEVDRFENEIGLIEKYRDSGALEVHMSSPQYQAFAAKASELIVEGSISVKYYGSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0H3</accession>
    <name>M5G0H3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630640.1">
        <property type="nucleotide sequence ID" value="XM_040772292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0H3"/>
    <dbReference type="GeneID" id="63687354"/>
    <dbReference type="HOGENOM" id="CLU_1042143_0_0_1"/>
    <dbReference type="OrthoDB" id="3406764at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="29284" checksum="B14C6578A0F2A9A5" modified="2013-05-29" version="1">MRLVGIRAALSCVAVFGPGIDQQTLSNDWQTTPLQHIHYILFSVGINEMNCQVASGGDLATLCVVHDLIYQFMDVYIHHHRTGQLLQLSVPLTIPTCEQMLAYLAAVCQGVLNPDPSSTSSMDTSSTLTFSPAVELPYISHLPSPILSPDPNKSMLLIQHLLEDVSVPNTLCYLTTTCHLTPPLAFVSAPSMEMSLPHPEISWHPSHLSKQSSDEAFLEQYVGPCLPVTMLLPAINKMLPLAFLVYFYELGSQDATLLTLDISLVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0S4</accession>
    <name>M5G0S4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_52165</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628617.1">
        <property type="nucleotide sequence ID" value="XM_040775085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0S4"/>
    <dbReference type="STRING" id="1858805.M5G0S4"/>
    <dbReference type="GeneID" id="63690147"/>
    <dbReference type="HOGENOM" id="CLU_008438_2_1_1"/>
    <dbReference type="OMA" id="WAPYILE"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="242"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="626"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="349"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="434"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="503"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU01720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="791" mass="89579" checksum="31BBE134C60ABCD1" modified="2013-05-29" version="1">MASLHGPSQFRPRQAYTDPLLSPPPPPPPPGPAPSSPFPATPSYKARPVGPRYSQSRGKPHPPGGIKLHKGEWKLLLLVCAVAVVVRFWRLGWPDSVIFDEVHFGKFASKYVKSQYYVDVHPPLAKLLITFAAFVSGYDGNFDSKISESALYEHVPYVAMRSLPATLGVLLVPITYLTLRALDCRADTALLGSLFITFENGLLTQSRLILLDSPLLFFTALTIFFWVGFANENRAAPFTHSWWVWLTCVGLSLGAVVSCKWVGLFTIATIGLCTIRQLWVLLGDTRVSIALWIRHFLARALCLIAVPATFYMAMFELHFLILSNSGDGDGFMSAEFQHTLNGKKMADTYADVGVGSKIVMRHWNTNGGFLHSHDHSYPGGSKRASLPFSSPHANRTRRTTNHPYPHLDVNNGWRILNATWDNHSPGYDWETEPFRALADGDMIKLQHIAISKMLHSHDIRPPVSEVDFQNEVSGYGFTGFSGDANDYWVVEIAEGDRRDRASSKRVRTLRTLFKLKHALTGCYLFSHKVKLPDWGYEQQEVTCNKNAVRANSLWFIELSEHNKLPATSPKVNYRKPGFLSKFLELQQVMWTTNAGFTERHAFDCRPNTWPILRRGINFWVKDHRQIYLLGNPVVWYLSTLAVALYFFARGMLILRAKRGYKDFNNSGLVFYDNLCSFLVLGWALHYAPFFLMARQLFLHHYFPALWFAVLLSAAVYDMATSKLKPRYRVQVALVLVGLAVWTYSHFNPLVYGSVWTRGKCESSKWLKTLDFACGDFYPNVSLCQPSARRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0V2</accession>
    <name>M5G0V2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication factor-A protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624315.1">
        <property type="nucleotide sequence ID" value="XM_040769316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0V2"/>
    <dbReference type="GeneID" id="63684378"/>
    <dbReference type="HOGENOM" id="CLU_2026652_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13323" checksum="D74180672B2101C2" modified="2013-05-29" version="1">MSATDILTAGTCQNLLDSVPPVGGMVQCIGIHPVLMPAVEEHAVRLCLTISDGNNCLDVVASFNLASDVVQGYLRLYDIIRIISYETFVCYEHKIVILKHVTGPYLSMGIIRQPTMLSVQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G108</accession>
    <name>M5G108_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Hydrogen voltage-gated channel 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_59339</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624365.1">
        <property type="nucleotide sequence ID" value="XM_040775553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G108"/>
    <dbReference type="STRING" id="1858805.M5G108"/>
    <dbReference type="GeneID" id="63690615"/>
    <dbReference type="HOGENOM" id="CLU_076372_1_1_1"/>
    <dbReference type="OMA" id="WEDEELH"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="16">
        <location>
            <begin position="55"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJT97467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="232" mass="26460" checksum="CC7CDD90BD07E2D5" modified="2013-05-29" version="1">MSSSRETQPLLSTVEAAPPADIEAAHPEDETLDEVAENEKFTWRMWTAEKLESKRMHWFILTLIIIDSSLVVADLAYTLLQTQCPPPEERPLPLELSEYASILISSIFVLEIPFSFWALGWEFYDPFYGVAHAPLHCVDAIVILGTFVLEVVLRGRDRELAGLFVLLRFWRIVKLVGGVAVGVGEIDEESAKRLAKARIRIRDQDRQIDRLIRENVDLKRRIAYAEQDLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1B9</accession>
    <name>M5G1B9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_82030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626519.1">
        <property type="nucleotide sequence ID" value="XM_040776545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1B9"/>
    <dbReference type="STRING" id="1858805.M5G1B9"/>
    <dbReference type="GeneID" id="63691607"/>
    <dbReference type="HOGENOM" id="CLU_005049_5_0_1"/>
    <dbReference type="OMA" id="AREPCIH"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="31"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="344" mass="38275" checksum="E1CBD13E9A572C51" modified="2013-05-29" version="1" fragment="single">MPVSMDTMRSEEPSNKTLVTNGHAQYSASARRLIVCFDGTSNLFDEANTNVVRFVSYLKKDDMDQQQVYYQTGVGTYIKPGMFMPLTVKLAELIDDGVAWDLSAHIMGGYRFLMQNWTPGSKISIFGFSRGAYTARALAGMLQKVGLLPRGNDEQIPFAYNFYANDSAEGYRMSTGFKRVFCHQVTVDFLGVWDTVASVGLFSARDLPFSTQDHHIRVFRHAVSLDEHRVKFKENLWHFATGPPDSTPAGHPSLWTTSTSLDRCAPTPFATDSEEVWFSGGHGDLGGGAVKNYVQSSPNRIPLVWLIREVVLANTGIQFNQAALDADGIRLPVMNPPKDGRDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Z1</accession>
    <name>M5G1Z1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translational machinery component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_58594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624675.1">
        <property type="nucleotide sequence ID" value="XM_040775506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Z1"/>
    <dbReference type="STRING" id="1858805.M5G1Z1"/>
    <dbReference type="GeneID" id="63690568"/>
    <dbReference type="HOGENOM" id="CLU_072439_4_2_1"/>
    <dbReference type="OMA" id="RPYYLHA"/>
    <dbReference type="OrthoDB" id="1654884at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10215" checksum="3CD0C2A8E384DBAD" modified="2013-05-29" version="1" fragment="single">SGGTVGFKKVNRESYEAGYQCGLRMIKAIETLLDKQDVRLEIHLDGFGQGRDAVMQSILGSEGLRMRTCVRAIVDTTKIKFGGVRAKKLRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G232</accession>
    <name>M5G232_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624720.1">
        <property type="nucleotide sequence ID" value="XM_040771356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G232"/>
    <dbReference type="GeneID" id="63686418"/>
    <dbReference type="HOGENOM" id="CLU_1085953_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067448" evidence="1">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="256" mass="28162" checksum="44D961E408EE709D" modified="2013-05-29" version="1">MQLLTFTTVLLITLSSLLVAATPIPVPDSTESRLALREADDPWSIDDLYSRTIDSDAEYVDYGLTLRDNVDDNGVFDVRDLLDDVNELEERQGSQAVHTNIKHGMQKVGKTVKKAIIGAYLVATKPSTDLYFEPGTTAVAAEQPLIVNSEPESKEPSAAFTNEVEQMIRPLSACAYPWRACTMSIPGPRTTNRGLWHHSLSQRHDSPSSRMLVIVIESGIALWTGYVIALLPPVGETELPLSWHGCSHGQRETFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G236</accession>
    <name>M5G236_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624725.1">
        <property type="nucleotide sequence ID" value="XM_040773851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G236"/>
    <dbReference type="STRING" id="1858805.M5G236"/>
    <dbReference type="GeneID" id="63688913"/>
    <dbReference type="HOGENOM" id="CLU_987024_0_0_1"/>
    <dbReference type="OrthoDB" id="3239894at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="28213" checksum="DD023DA287FEA0A2" modified="2013-05-29" version="1">MGEQVRRFGPVHGFWTFMFERLNKLLKGVEVGTLANVVVHAQREVQELIELEKSPVHGTAYNRRLDSTMQDKLLAWYHRQYPDQALFKATDAKALPGSLYLVLQATHYPQLRVGSYKLYATEVDRPNKSNALMQICFERRVQWVGELCDIFQHMQPGIGKCLTFALVDWLVPLQDLPSYADLYHPYPELEVDFWEPGQYLQDTEWAPPALILAEDICGVAARCTMEFEGRRMWITTGMSKDGKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2P2</accession>
    <name>M5G2P2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_115262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629858.1">
        <property type="nucleotide sequence ID" value="XM_040769968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2P2"/>
    <dbReference type="STRING" id="1858805.M5G2P2"/>
    <dbReference type="GeneID" id="63685030"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_3_1"/>
    <dbReference type="OMA" id="WTFMQIF"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF64">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006528040" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="495" mass="53841" checksum="DB4F3A5C2E52757D" modified="2013-05-29" version="1">MQLRVLSLLLPASGALASQIPRIDDIIGGVRTIAPLRNTVAIPKNQYFQAGVAPLRYIENSGICETTPAVNQAVGYADIAYNQTLFFWFFEARNDPYNAPLSIWLNGGPGSSSMLGLFQELGPCRVTLDGSNYTLNPYGWNEYSNMIFIDQPTTVGFSYGTANVGTAMEAAEGVWTLLQMFLSDPKFAHLQKNQFAVWTESYGGHYGPAVSYHILQQNALIEAGMLHGIKLNFQTLGIGNGLTNPLVQYPQYLAYALNNSYTVPLVNTTVSTNASIHLYESGGCLDQISACYDSTLLNGSPNDTACSAAQSYCNQYVLSPLVGKYNDYDVRVVNPDPYPPDLTNLLNSPWLTSKIGIPSFVNWTETSYAVYENFAATGDWMTNSAPYLEAVINSGIRTTLYDGDTDYICNYKGFEAVTANLNTKFSSIYAAKNFTPWTVEGYPAGMIKNAGTFSFVQVAGAGHEVPAYGNGPLQAGQAALVFFTQTMKGLPITST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2V1</accession>
    <name>M5G2V1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_33129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629918.1">
        <property type="nucleotide sequence ID" value="XM_040774366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2V1"/>
    <dbReference type="STRING" id="1858805.M5G2V1"/>
    <dbReference type="GeneID" id="63689428"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_57_1"/>
    <dbReference type="OMA" id="TPLACPK"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF76">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="36243" checksum="A9C657EAF23D8AD5" modified="2013-05-29" version="1" fragment="single">PKPTNDEDGQVVGDYTLGRVIGTGAFSEVRRAVNNLKGTVVAVKAIRKGQTPSSGTGGCQELAERESALWFGLSHENILPLFATFDTPYTVYLVMLYCPAGSLLQLLNDTHRPGAGSGLPQPEAERLFAQIVCGVTYLHRTAQIVHSDLKLENVLLDSEGRCRIADFGLARHIGDPAMELAHAEQEGERNAAGGLVRARTWQARHSSPAPGKRRPLAGGRQTFHPGSLEYAAPELLRPAPSFTSVSASSSTPHNPEDVANPAQDIWALGCILFALLTGLLPFTDSFQPRLQMKIVRGTWSVPADIGRRAEELLKGCLCMDVQERWDVGAVAECAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3F7</accession>
    <name>M5G3F7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630098.1">
        <property type="nucleotide sequence ID" value="XM_040774989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3F7"/>
    <dbReference type="GeneID" id="63690051"/>
    <dbReference type="HOGENOM" id="CLU_013084_0_1_1"/>
    <dbReference type="OMA" id="DAYYWIV"/>
    <dbReference type="OrthoDB" id="2676448at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="17695" checksum="FEC893FE77469E6B" modified="2013-05-29" version="1" fragment="single">LDKLEGLVVQHLFEIEKCNLCGTGYKMCTSISKVLKQRSTTIQGALMRYNKLAWDLSWPMLSFQEVLDYSFLSDFALLQYSQNDILKQKWASPKVCQATIKWLHMECMKQEIKWLDVEIQPVWTSIHIEPPCLKHKVKEAQAQGDKLLTCKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3R8</accession>
    <name>M5G3R8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_100667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627394.1">
        <property type="nucleotide sequence ID" value="XM_040767477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3R8"/>
    <dbReference type="STRING" id="1858805.M5G3R8"/>
    <dbReference type="GeneID" id="63682539"/>
    <dbReference type="HOGENOM" id="CLU_1357486_0_0_1"/>
    <dbReference type="OrthoDB" id="552194at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="202" mass="22300" checksum="EE247B6250961C1E" modified="2013-05-29" version="1" fragment="single">MANRAAPLGLKFAKRISPAITHFVIDTLDLSSEKLYVSLMACAEIVNHAWWEEVCTRASTPRGEEGSWEDEFVQLERTARWTPELEDGFTEAFLEVDERRRSLFDGLTVVLLSDASTQSEVISQLNLGGALVETIDLLEAETTAVSLLPQLLSMQKTAVAGLQISTSANNGTQSSGLRVVLAKDSVKEALRRTWVKYEKIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Z2</accession>
    <name>M5G3Z2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627459.1">
        <property type="nucleotide sequence ID" value="XM_040770308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Z2"/>
    <dbReference type="STRING" id="1858805.M5G3Z2"/>
    <dbReference type="GeneID" id="63685370"/>
    <dbReference type="HOGENOM" id="CLU_022672_2_0_1"/>
    <dbReference type="OMA" id="WTFDTWN"/>
    <dbReference type="OrthoDB" id="2527403at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018803">
        <property type="entry name" value="Ish1/Msc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10281">
        <property type="entry name" value="Ish1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067460" evidence="2">
        <location>
            <begin position="19"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="499" mass="56378" checksum="D655B04E2BFD21D1" modified="2013-05-29" version="1">MRVHNILLLVILATSATAGWFGGDKDASAVPEFSSWDGEKLASHLKEQGISVPHGFTRDELVALAKANYDAVNSWEKAHVEHAQKVFSDAKESLVDGWTESQLREFLLEQGIIAPASRSEQLRLLAKTRYKALSSAVSSYSAAFSTAIHGDATAQASKSLNSAAAAASRSATAAAAEASRNIQRAMDESKDFIWSEWSDSDLRNWLEEHRFVKTKAELKREELLEKMKHAYTTVYNPAYEAWSTSYIHEWLVANGVIKSDYQQARDKLLHLMKENYYSTQDKVYQAWSDSDLKVWLVEHEVIKSDAQIKREKLIKLMDDHYNHARDIIWSSWKDSDMHDWLIDRGYLRSEAQARRDELEGLMHEKYDQVQQYAAAYLTWPDARLRAYLRNNGVDDTKIPGMDRTTLLQETRIRWVQTTSALDDILATIRRYLMTGTEFAEDKVEDLKELLGLGKASLEREFKKEKKAAYDAASDTAKSASSAASKLSSVASSASAKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G420</accession>
    <name>M5G420_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_49842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630318.1">
        <property type="nucleotide sequence ID" value="XM_040774943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G420"/>
    <dbReference type="STRING" id="1858805.M5G420"/>
    <dbReference type="GeneID" id="63690005"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OMA" id="PKPFIEH"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="259" mass="27329" checksum="514DB87925EA5B22" modified="2013-05-29" version="1">MPATYPELKGKVALITGSSRGIGKEYALALGAQGVNVVINYHSSAETAAAVVDAVKQAGGDAIAVQGNVSNVSDIAALFEQAKKHFGKIDIVISNAGVEHFSDLDKTTEDDFDRTFGTNIRAQFFVAQQAYRHVTHNGGRVILTSSISKEMSIPRHSVYASSKGAVEVMVRNMKADFGPLGVTINAVAPGGTMTDMAAQSARDYIPGGKDKTDAEILALIKRMSPLGRPGYAKDISNAVLFLVSDEAGWINGQTIQVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4A8</accession>
    <name>M5G4A8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629954.1">
        <property type="nucleotide sequence ID" value="XM_040768228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4A8"/>
    <dbReference type="GeneID" id="63683290"/>
    <dbReference type="HOGENOM" id="CLU_1660694_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="159" mass="18312" checksum="1C12594EE2F57CC4" modified="2013-05-29" version="1">MDSQDIKKIRRCNAELQCQHDEIVADIEELRRGLLDAEDEVRRRRSRLEQAEKRAVRIKKDMARTKQILSQIEQAKATLALINRGELPGLDVPVRWEARARPMPRIGGMESLDTPRVVSEFKSKTQEWNRSAATQTLRLCLRTTMLKTRSTSTELSATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4K4</accession>
    <name>M5G4K4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_54053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627669.1">
        <property type="nucleotide sequence ID" value="XM_040775227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4K4"/>
    <dbReference type="STRING" id="1858805.M5G4K4"/>
    <dbReference type="GeneID" id="63690289"/>
    <dbReference type="HOGENOM" id="CLU_017716_4_1_1"/>
    <dbReference type="OMA" id="ETGNEHE"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="1">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="18380" checksum="C8DFDAF89797D5BF" modified="2013-05-29" version="1">MSLPAIGTRLSLSSHLGTVAYTGPVAGTSGEWIGVEWDDPSRGKHDGLHKGVQYFTCRVEGAGSFIRPGSGIHYGESFISALVKKYADPSTSTAPETGNEHEEKEETVLLGSSLGLITVQAPNIGKVRQRLAQLDRLREVSLDGEGVSHPGGAQELRERCPSKPIRGYSCYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4P8</accession>
    <name>M5G4P8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632120.1">
        <property type="nucleotide sequence ID" value="XM_040771659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4P8"/>
    <dbReference type="GeneID" id="63686721"/>
    <dbReference type="HOGENOM" id="CLU_2739954_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="71" mass="7322" checksum="DA80C1EE190B4433" modified="2013-05-29" version="1">MTALAAYPHRAGLFSCHPSHSPGRSVHSYVVTVNDASMCGLLLSVIFSQDSILTSGVADQGDGTDSELAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B0</accession>
    <name>M5G5B0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Replication protein A OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630314.1">
        <property type="nucleotide sequence ID" value="XM_040768298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B0"/>
    <dbReference type="STRING" id="1858805.M5G5B0"/>
    <dbReference type="GeneID" id="63683360"/>
    <dbReference type="HOGENOM" id="CLU_807880_0_0_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37278" checksum="E5F52123371F1056" modified="2013-05-29" version="1" fragment="single">MSWGYRVITVTAAVPYFEPTEIIGDPKEISLQLDAVVSAPLSIEEREGVTAHPSASSVSRRSVSNSLLYRTFTHDPSESACQNLHDENASTDCPNDVDAPLKPATTQAGPTNEETLGREGKGKEKPETGPRHLGWSGIGPAKTPLLSSIGSSVNQFLTDHPSLSFLAALEDKSKVNILGVILQVGKLVTKPIAMRSASVALDGSTQQASTKQKSRMLCEVQVVDKEGHVVRVTMWNSRAKIFSGKHGQVLHVMNSVVEHRGGVTLNSSEKTEFPLNPKIEEADELKQWFTDGFDEAALKHISCGYSKEGGLTSTTLEELPKVLTKAQVRASRLGHGDCIDYFNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5I8</accession>
    <name>M5G5I8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEBP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_82927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatidylethanolamine-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625920.1">
        <property type="nucleotide sequence ID" value="XM_040776598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5I8"/>
    <dbReference type="STRING" id="1858805.M5G5I8"/>
    <dbReference type="GeneID" id="63691660"/>
    <dbReference type="HOGENOM" id="CLU_035836_1_1_1"/>
    <dbReference type="OMA" id="FRTQWDE"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001858">
        <property type="entry name" value="Phosphatidylethanolamine-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01220">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="387" mass="44320" checksum="850F211929A379E4" modified="2013-05-29" version="1">MYITARRTASLCRRQLQRRLFSSQTYTRPLPAGALEVYDHALLFLAQDRDVKLARISSLQEELPSLTGEAAEGSKKEIARLEVEAWINDPEVRWMHNMGLWDMSKPVYRHLREQQWRKEGVLDLLMERLWQMHIIPDVLPWVDPTLDMRLQFPTERTEEVVKIKGKDDVVCQEGDIEPGTFVLPSQTSKEPQLYVTAFHPEERFYTLVMVDPDVPSPETQSYSTLLHWLVPNIPLSCLSPSSPIALPPALLPYIPPHPQQGSGYHRYTTFLLPQRALLTELKTPLRRNFNLRDFVRQYSLSGSPVPGAPKPILPGHGKKRNGVGEVTSLHTGAEVGGGGVHMFREVWDESVTALHERVFGVGERRFGKLKQGDPYVDEEGRRPRRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5T6</accession>
    <name>M5G5T6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SLY1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628054.1">
        <property type="nucleotide sequence ID" value="XM_040773017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5T6"/>
    <dbReference type="STRING" id="1858805.M5G5T6"/>
    <dbReference type="GeneID" id="63688079"/>
    <dbReference type="HOGENOM" id="CLU_016216_3_1_1"/>
    <dbReference type="OMA" id="VNDLRAW"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="677" mass="73967" checksum="028FD4C855D61E6D" modified="2013-05-29" version="1">MSTMKQQSLQELQTASLLAVLNLNEEPVASSSGEKSAPSGPTVWKVLVLDDHSKDVLATVLRVQDLREVGVTLHVQLHSQRPVIADVPAMYLVAPTLTNVQRIAQDLTDTLYESFYISFLSPLPRSTLEELASLVARDGTSELVQQVLDQYLDFICPSPSLFSLLPMTLPSQGNQLSAPAQTNGAGAHASAPSTYALLNSPATSEQTLEALTDHIASGLFSVLATMGVVPYIRCPRGNAAEMVSRKLETKIRDSIAGAGLGGRGGVFGRTDVGVMQRPLMVILDRNVDLISMLSHSWTYQSLVHDVLEMNLNRVTVSTPDHGKMQKKSYNFDRSDFFWEKNAGNPFPQVAEDIDIELNRYKQDAAELTRITGVSNMDDVSQMDLANNTAHLKEAVTQLPELTARKATLDTHMNIATALLQAIKSRALDEYFQAEENVTRQSMGAILEMLRMQKEGVQPTNEDKLRLALIFYLSSREDDKVDLGELEKELKKQSCDISAMEYVKKIREISRMTNLAAAAPAAQPSNTTNELFRGFSSLSNRLTDRLKEGGLAGVPGFDNLLSGVKNFLPARKDFATTRLVEALMDPATASTQALQDTDDFLFLDPRARVSAMGAGRGGKRMASQEGIVFVVGGGGYVEFGNLMEWAGRSGRKVTYGATELVRPGDLVKVLAELGSQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6P9</accession>
    <name>M5G6P9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626335.1">
        <property type="nucleotide sequence ID" value="XM_040773486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6P9"/>
    <dbReference type="GeneID" id="63688548"/>
    <dbReference type="HOGENOM" id="CLU_1320861_0_0_1"/>
    <dbReference type="OrthoDB" id="3415466at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067622" evidence="2">
        <location>
            <begin position="20"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="208" mass="22911" checksum="12FD5693FBAB9FB8" modified="2013-05-29" version="1">MHASTTSILIAALASSSLAAPIFPDPEALNARNLAARNVLYQLATRDTPTADHSKQNQNEHPISARSVEQKDELDERDLEDFPQFDERDEDNSLDKRSPINVFATSKAFARSALGKGRAGRSFVTGVAKRGSKHLKALVAGVVKGNTDTVQGVKENVGNQDQQQRSLDDIDDDMDVYARSLPAEEFEWQTWEARTFLPEQVETSNGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6V1</accession>
    <name>M5G6V1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631328.1">
        <property type="nucleotide sequence ID" value="XM_040772170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6V1"/>
    <dbReference type="GeneID" id="63687232"/>
    <dbReference type="HOGENOM" id="CLU_2120991_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="114" mass="12627" checksum="99A5DC7F19B135EF" modified="2013-05-29" version="1">MTEIDCFSVACACMLNRKQPTQPYSHWCLLILSSIIGGVLLQVHQSWEEEVVVVYELLGVTRFDGSRGRQQGRAPVRRHARGPAHAQLIECALTGASTYEQIHPNPVGKASRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G774</accession>
    <name>M5G774_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_39017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628564.1">
        <property type="nucleotide sequence ID" value="XM_040774453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G774"/>
    <dbReference type="STRING" id="1858805.M5G774"/>
    <dbReference type="GeneID" id="63689515"/>
    <dbReference type="HOGENOM" id="CLU_070882_2_1_1"/>
    <dbReference type="OMA" id="RVFYFNR"/>
    <dbReference type="OrthoDB" id="9936937at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058841">
        <property type="entry name" value="HTH_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040554">
        <property type="entry name" value="KPWE_PEX14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855:SF1">
        <property type="entry name" value="PEROXISOME MEMBRANE ANCHOR PROTEIN PEX14P N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25871">
        <property type="entry name" value="HTH_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17733">
        <property type="entry name" value="KPWE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEX14-like helix-turn-helix" evidence="3">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisomal membrane protein PEX14-like KPWE" evidence="2">
        <location>
            <begin position="94"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="142" mass="15710" checksum="02B24DE322FCD5EF" modified="2013-05-29" version="1" fragment="single">IDAFLAYPFDIDQEFQEGLQSILSTAPPEAELSNTILRAQLFYFNRKTGLSLNPHELAASESSNKQEEAVETEKSESQQVEPHTAAPPSAGDAPYPLSFAQLAELIQSNRTDLIPNNDIIPNTVLEGQSSESRTPARRKPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7D9</accession>
    <name>M5G7D9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20741</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630999.1">
        <property type="nucleotide sequence ID" value="XM_040772060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7D9"/>
    <dbReference type="STRING" id="1858805.M5G7D9"/>
    <dbReference type="GeneID" id="63687122"/>
    <dbReference type="HOGENOM" id="CLU_961547_0_0_1"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU04105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="290" mass="32555" checksum="9199B5EAF86BCBDA" modified="2013-05-29" version="1" fragment="single">EDDNSSAVDDNESFASVDDLDADEEAHKMDLESLKEVDPKFYKYLQENDKELLEFGNEPEEIKDAEDVDVEVDEAGIAMEEEEDEITVPSTAKEVMKEMLHAWQRRLLLAFRVAVHMNEEDGTQYAYSIGSSAVYNKLVVAALKYTSIVLSHHLPYKTLPDRCYKPPAQTKKHSTLQKMTLSFFGNVLHLLSQLPDGDMKLLILSESTKVIPYIVSSRKVVKDYLKQLLAGSMTDLCLSRPLFTGNDGAHLPSINLMKNSAMELYTLDHEAAYQHAFRISASSPSTSGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7Q2</accession>
    <name>M5G7Q2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Uricase</fullName>
            <ecNumber evidence="7 10">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_62965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 10">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 10">Belongs to the uricase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="7 10"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631668.1">
        <property type="nucleotide sequence ID" value="XM_040775719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7Q2"/>
    <dbReference type="STRING" id="1858805.M5G7Q2"/>
    <dbReference type="GeneID" id="63690781"/>
    <dbReference type="HOGENOM" id="CLU_048151_0_0_1"/>
    <dbReference type="OMA" id="ATMYKMS"/>
    <dbReference type="OrthoDB" id="9992118at2759"/>
    <dbReference type="UniPathway" id="UPA00394">
        <property type="reaction ID" value="UER00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004846">
        <property type="term" value="F:urate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.270.10:FF:000001">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4 7 10" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU04774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="313" mass="34026" checksum="63AB3052A5F652A8" modified="2013-05-29" version="1">MAELTAARYGKDKVRIFRVVRSVKGDPQAWHDVVEYNVKALLEGDIAASYTKADNSVVVATDSIKNTCNVFAKTSPHVLHPEQFALDLGVHFVTTYAHIHKAFIDIEQLKWSRITVSKDGQPHRHSFVRDGDEKRLTSVEVDATKGKNAITAKVTSGLSGLLVLKSGGSAFEGFVRDEWTTLVEVDDRIFSTEVDLSYTFALPVEALTAAGIAALQDKVGFDKASESAKQITLDLFATDESASVQATLFKMCSEIIAASPSVESVSYRLPNKHYIPVDLGFKGLANLKPVDAEVFCPVAAPSGLITATVSRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7T7</accession>
    <name>M5G7T7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628844.1">
        <property type="nucleotide sequence ID" value="XM_040772767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7T7"/>
    <dbReference type="GeneID" id="63687829"/>
    <dbReference type="HOGENOM" id="CLU_3068625_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="53" mass="5750" checksum="5D4D122DB331BBC8" modified="2013-05-29" version="1">MKKSFTPMALAFAREEEDLVDKLGHDEVAERAGPGDSEALVPVIGAKCSWCGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G877</accession>
    <name>M5G877_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_98713</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631863.1">
        <property type="nucleotide sequence ID" value="XM_040777543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G877"/>
    <dbReference type="STRING" id="1858805.M5G877"/>
    <dbReference type="GeneID" id="63692605"/>
    <dbReference type="HOGENOM" id="CLU_028760_2_0_1"/>
    <dbReference type="OMA" id="TCYGGRL"/>
    <dbReference type="OrthoDB" id="9972683at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="75"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38586" checksum="776B28B2AD038BC7" modified="2013-05-29" version="1">MPRKLTPEQEAMKVERFELGDFELECRAQTTDWFLMYRCIGDAKNPAILKPTCFGGTIRGSDVPVGEEHTITPARYYIIFVGMFGGSESSSPSNTNAPFNGGNFPPISLADQVNAQKKLCDFLGIKKLFAVAGFSMGACQAFQWGVQYPDYMDFIIPVCGSARCSPHNYTFLEGPKNALLADQNFKGGHYTTDALPRLGTKGFARAYSGWGYSSAWYTQGKFLDLGFKDLDDYLVQAWDGSLGTTDANDLLCLTRTWQTANVANIPPYNGDFEAAMKAIKARALVMPCTTDQYFEAEASEIEVSLMSPGIGMYKPIVSIYGHQAGANSNPTDTKFFNEAVAELFAEVEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8A2</accession>
    <name>M5G8A2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631269.1">
        <property type="nucleotide sequence ID" value="XM_040772147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8A2"/>
    <dbReference type="GeneID" id="63687209"/>
    <dbReference type="HOGENOM" id="CLU_1496159_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="19355" checksum="B6508BF4FB03CEC3" modified="2013-05-29" version="1">MNQLCGSSTSTSPNLPGGRCRSNLSHSGALLSYTIRSSTIPTLIPGHARICSLKASTSRSSVCPPCRSQNTSSLTWGNNTLYSNSRHHVLSLFVPSLRSLPIRGHAAIQLSIPRFCHLRSEKGSMKLGESTTSSSSSSNWPSTPGQKWQSRTRRAKSCTTRRRLSVGPRAENSGASSLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8W7</accession>
    <name>M5G8W7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_95557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627100.1">
        <property type="nucleotide sequence ID" value="XM_040777302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8W7"/>
    <dbReference type="STRING" id="1858805.M5G8W7"/>
    <dbReference type="GeneID" id="63692364"/>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_1"/>
    <dbReference type="OMA" id="PCLSWED"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="9">
        <location>
            <begin position="52"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="368" mass="40232" checksum="69AEFA294DF88D57" modified="2013-05-29" version="1">MPVSDYDTVDKWIVDRRILGYDPLVQPALLKHEIPLSRSSQATIARGRWEAAQVIQGSDDRLLVIVGPCSIHNPESAMEYAKKLKSRLHTWDNLLIIMRAYFEKPRTTVGWKGLINDPNIDGTYQINKGIRIARQLLADISALGVPVGSELLDTISPQYIGDCISWGAIGARTTESQLHRELASGVSFPIGFKNGTDGSMTIAVDAMKSANHPHAFMGVTEQGLAAIVKTKGNQDVHIILRGSNTGPNYEQEFVKKATASVIKARPGFHPAIMVDCSHGNSSKDYRRQPIVTESICEQLRAGDMNLVGAMIESNLCAGKQDVPPEGPKGLKYGVSITDGCVDWETTITMLDKLNEAVATRRKVNASNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y2</accession>
    <name>M5G8Y2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632073.1">
        <property type="nucleotide sequence ID" value="XM_040769617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Y2"/>
    <dbReference type="GeneID" id="63684679"/>
    <dbReference type="HOGENOM" id="CLU_868841_0_0_1"/>
    <dbReference type="OrthoDB" id="4738875at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35829" checksum="FEDA1FAA8AA6A890" modified="2013-05-29" version="1">MMVSQGGRGKDTNTSWIALRILEEQEHLTRTDRRDIQFTMSSVPSVEAASSSSTPASVPEPEISIRRLLSPTPSEVQAALEVLRISFSKSAFFAAILGGNVSPERMAAAHELFLRAALVRGEGEVWIAESFFPEEPEKKEVVGAVLWFLPGTEFLATEKQRKAARWEEFARMLGVQSRWLTDYYLPRIDAFWTRALPYGPSHLESYELCKLAVLPNSHNAGIASLLVWPVLSRAVREGKRVVGETTSEGNVSKYLRVGGQQVGEERFYAFDARGRPTEEGEPAFRIWGLEFQLGQVGNGHWSRTNERDEQNEKGITRACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9E1</accession>
    <name>M5G9E1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF572-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_33173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631744.1">
        <property type="nucleotide sequence ID" value="XM_040774368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9E1"/>
    <dbReference type="STRING" id="1858805.M5G9E1"/>
    <dbReference type="GeneID" id="63689430"/>
    <dbReference type="HOGENOM" id="CLU_050402_1_1_1"/>
    <dbReference type="OMA" id="CNNCENI"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="216" mass="24781" checksum="E1E05F273111BF0F" modified="2013-05-29" version="1" fragment="single">MQGFNKYYPPDYDPEKHKNLNAYHGKHALGDRARKIDKGILVTRFELPFNIWCSTCNAHIGMGVRYNAEKRKVGNYYSTPIYAFRCKCHLCGGWFEIRTDPQHTRYVVESGARQKDEEWDPAAAGGYAVHDPEAAGEADPLAALEKTTSALKRIDQVERPRIDSLQELSERRTADPYTVSSKLRKTFREEKKLLEAQRLADEGLKDKYGLNEEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9I4</accession>
    <name>M5G9I4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_19946</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 7"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632348.1">
        <property type="nucleotide sequence ID" value="XM_040771730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9I4"/>
    <dbReference type="STRING" id="1858805.M5G9I4"/>
    <dbReference type="GeneID" id="63686792"/>
    <dbReference type="HOGENOM" id="CLU_013615_12_1_1"/>
    <dbReference type="OMA" id="HDEICVE"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="20"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="11706" checksum="D5965982FB92AF81" modified="2013-05-29" version="1">MGVTIQTLVAGDGVTFPKPGESVTLHYVGTLTNGKVFDSSRDRRLPFTVEIGEGRVIKGWDEGVPQLSLGQKAILTITPDYGYGDRGYPPIIPPGATLFFEVELLKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Q5</accession>
    <name>M5G9Q5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_114309</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631909.1">
        <property type="nucleotide sequence ID" value="XM_040769795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Q5"/>
    <dbReference type="STRING" id="1858805.M5G9Q5"/>
    <dbReference type="GeneID" id="63684857"/>
    <dbReference type="HOGENOM" id="CLU_015166_14_2_1"/>
    <dbReference type="OMA" id="HARRYCS"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="34"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="132"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="236"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="327" mass="36211" checksum="F209DF10477697A1" modified="2013-05-29" version="1">MDEDLIPLTGQTAPPPLPPSPPHVPQRWRESESYQVLMRIPLAGVSNMFSSALTNPVDIIKVRQQLRTSPSLPGTFWAIGSQMIRTEGPLSLTRGILAGVMRESIYGTIRLGTYEFWKETWKRLSAGRLDERGLPLKVMSALTSAVVGASLANPTDLVKIRMQAPYPPGHPPPYRSTLYAFRSVYLEGGGTLLGGMRSLWRGTGPTVARGIVISVSQIVGYDQCKQTLKYGMGWGEGLRLHLAASLFAGLLCSITSNPVDVVKVRIMNDSNRQYRSILHCVGTILRNEGTTAFYKGFMMCWARLGSHTVVTYLIFERLRMWAGVRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V2</accession>
    <name>M5G9V2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629551.1">
        <property type="nucleotide sequence ID" value="XM_040772500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V2"/>
    <dbReference type="GeneID" id="63687562"/>
    <dbReference type="HOGENOM" id="CLU_2621977_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="78" mass="9348" checksum="641CE022BE7E5143" modified="2013-05-29" version="1">MRRNLALACWNQDTWQACTDLSENASQSGDQSLWSLDMDRMYKNDPLSKIVKRSCIGSVILRRMRRRFRQRRLGRVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA64</accession>
    <name>M5GA64_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_66006</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629731.1">
        <property type="nucleotide sequence ID" value="XM_040775801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA64"/>
    <dbReference type="STRING" id="1858805.M5GA64"/>
    <dbReference type="GeneID" id="63690863"/>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_1"/>
    <dbReference type="OMA" id="KGMTAHY"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="16"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="339" mass="36545" checksum="66D0DC0D95C9CA16" modified="2013-05-29" version="1">MSLPKTTKAILVQKTGGPEVLALGEVATPTPSADKVLVKVEWAGVNYVDTYKRAGVYTLPLPLVLGEECSGTIVALPTSESVLNSEQYALRNFHVGDRVACTVSGSFAQYAAASWEKCWKLPVNVETKIGALCVLQGLTALTMIRETYTVKKGDYVLVHAAAGGVGLLLCQACSYLGAHVIGTVSTLAKAQLARENGAEHVIISKEQNVIQEVMKLTDGKGCHVILDGIGKDTWEDDFEMIRRKGTIVTYGNASGVVPPFAPLKLAGKNIKVARPTLGNYIVTAEESAEYFSWLFELIDKGVLKFHVHDEYPFTADGVRKSQTDITSRGTTGKLVIKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAF3</accession>
    <name>M5GAF3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63684772"/>
    <dbReference type="HOGENOM" id="CLU_717661_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="385" mass="43326" checksum="C6C264F1D6BE94E9" modified="2013-05-29" version="1">MPSKRRHATSQRSPMAASEFADLKDTEAFHDYLCSVHADCMYIREGAGDTGVPWADMPDVIRSDFISLPEGHRGPFLPQTLKNWSEDTHISERDVRFARALSELDESVWIPPSSTSTSNIGPADIPHLSVIYTHIHQVEEVKKIGVHPSELMMRGPIDFMLRICCDDKLNSQEDQDAFNVAILMEQRRQRAALGLPKRVQYGLACGTAHIAVIACMLNSDNGCNLGPAQCWRSSPMLLLCPCCRKSSRSCCDELDLAIDRLTTVPRELWWRAEDEPPQWESPASPRAKKRKTLKKSLSGRAPPQKPQPFVVPAEDFFHVCNTLFSTKGVMSAADEARWLELSEAREKLESDIKPTESYIRGSDDTQSRIEAWTRQIQPVIQDPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAN3</accession>
    <name>M5GAN3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632319.1">
        <property type="nucleotide sequence ID" value="XM_040771724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAN3"/>
    <dbReference type="GeneID" id="63686786"/>
    <dbReference type="HOGENOM" id="CLU_1348881_0_0_1"/>
    <dbReference type="OrthoDB" id="10619386at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="203" mass="21724" checksum="F79855E701EE33C2" modified="2013-05-29" version="1">MLAARAMVPVSFELHSTPSTSEASSVTSSAQISPSPSMDRIHLITPSGRALKTARGVLPHPGELTPEESEDEQGEEGDGGRKRSPLVPVRGRFVLGADEEDAVTSKDMIDTEPVSAVPLVRLPFTLHITLSIDLLQPSAFFDTCYFLHSLFVIGIGEGFYQRGVCGGVYAHTSSSPFQLSSPQAVLSSSLLSLWPRTSPARAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAX2</accession>
    <name>M5GAX2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras GEF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_77997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630026.1">
        <property type="nucleotide sequence ID" value="XM_040776303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAX2"/>
    <dbReference type="STRING" id="1858805.M5GAX2"/>
    <dbReference type="GeneID" id="63691365"/>
    <dbReference type="HOGENOM" id="CLU_002632_2_1_1"/>
    <dbReference type="OMA" id="KIWAFKP"/>
    <dbReference type="OrthoDB" id="28357at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF354">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="4">
        <location>
            <begin position="48"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="249"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="524" mass="58770" checksum="0069CF74824C579B" modified="2013-05-29" version="1">MPSFTSSVEDTLESGDLAFQPQPKLSPGHVNDWIIKDDDEPADVLLNPDETVIGGTLPALVKRMTPHVVTPELSFSSSFFMTFRLFTTPLDLADCLVKRWDMQVWHDRMLVPIRLRILNFVKNWLESHWQAGTDAPALVHLQFFVDQVPDGILKAASRKIGDLISTRRLRPESIHNKYAAVTISQATAPRSLDRTKSFDRMRSATPLPFGNGAASYASANPPPAPMVGRSLYSTLRAGTFSAINVTDFDPLELARQLSVMENKLYIAIQPQELLQLGKSGAPPAVNVKAITTLSTAITGLVTESVLSEYDIKKRTNLLKYYIKVAERALELKNFSLLFSILAALTSSTVLRLNKTWAGLNSKYRTKLEELRKVTDYTRNYGEYRSRLRETEPAAIPFLGVYLTDITFCNGGNPSHRPSPVRSDVQLINFNKYRKLARIVFDMQRFQKAYNLLEINEAQHFLQFALRESRTSGDHKDLYRRSLLIEPRESSAEPASADTVKSRTDIFGWAARSLGQTNTANTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBB2</accession>
    <name>M5GBB2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycosyltransferase family 49 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_113733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632569.1">
        <property type="nucleotide sequence ID" value="XM_040769689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBB2"/>
    <dbReference type="STRING" id="1858805.M5GBB2"/>
    <dbReference type="GeneID" id="63684751"/>
    <dbReference type="HOGENOM" id="CLU_601315_0_0_1"/>
    <dbReference type="OMA" id="SGQYRIY"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067620" description="Glycosyltransferase family 49 protein" evidence="7">
        <location>
            <begin position="28"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU05675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51241" checksum="0D4AE16250BD0BB0" modified="2013-05-29" version="1">MARPNTLFTLVAVAVFVLYLLHNPSRTSTPITAIVEPQQPEAQVQSAIHHVLTLPHHLHTYSSDDVLDLPSLPSGPHNAAFSPPTWYQELSTESIEQAIASLLAMDNPDAPSNKNNSAPIQVLPFYYRAARSPDPSAITITTLVTPSRYPVLSRLASHYNGPISVAVPFQSPLSLPSLHEFYTSNPAIVEHVDIHLILNSPPRAFNTWRNVARAFARTDTILMLDVDFYPCTPFAQRIQGSQIALNLLENNAMLVLPAFEYASIDAGKYTSLFPVAKRDLLPLLENGEIGQFHGAWRPGHAATNYSRFANATSGEIYKVKDYHPSYEPYVIFQRENAPWCDERFIGYGANKAACLFEMYISGRSFYVLADDFMIHQSHQYLESTRKAERQLNKKLYPSFREEICLKYLKHYVESAIMGSQITHNARNECMKIAKIRKKFPMMLAGKRLQVNGMMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBS7</accession>
    <name>M5GBS7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633338.1">
        <property type="nucleotide sequence ID" value="XM_040771581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBS7"/>
    <dbReference type="GeneID" id="63686643"/>
    <dbReference type="HOGENOM" id="CLU_2426976_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="91" mass="9308" checksum="CC65D77E486DC537" modified="2013-05-29" version="1">MGYCVGCGRGACRMMGQQFTLKSCGYTTGGWICLILVFATVVIGLIYYARSGGVGKWAHEAMDAAFPTGTGAAGAGSAVSSSTSSNRTTHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCA1</accession>
    <name>M5GCA1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_19417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633019.1">
        <property type="nucleotide sequence ID" value="XM_040771500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCA1"/>
    <dbReference type="STRING" id="1858805.M5GCA1"/>
    <dbReference type="GeneID" id="63686562"/>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OMA" id="TGDDWNP"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU06125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="382" mass="41564" checksum="205AC25008C4EE67" modified="2013-05-29" version="1">MAYGATSSAPTVLVTSSTSFLGAHTVLELVRRGYLVKAGVPSVALARQFLKQHPACAPALEWTILPSLTSPRAVEEAVRDVDYVIHVCAPFAMEYEDPMDVLLPAVEGTHALLAAAARQPRVKHVVLTSSLGAVLDPSRGLAPGITYTPSSWNPATWESALAASDSVELHLASKTLTERSAWDFLSTFNPSFALTTFCPPVILGPPAQPLADLSPQSLGESVGQAWQILSGAYDPLPPTRFPLFVDVRDLARMEVAALGRPETMGRRFLAVGGEFSNSQITALVRLQYPSEPRLPRTPPTKPGRHSRVDVINTEAVFGTEWTSLAQSVRDMAEVLFSRERELRKEEKGRVWWSRTTGGRTSPDDTDRLEITHVEGMMTVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCA8</accession>
    <name>M5GCA8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_61496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633563.1">
        <property type="nucleotide sequence ID" value="XM_040775673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCA8"/>
    <dbReference type="STRING" id="1858805.M5GCA8"/>
    <dbReference type="GeneID" id="63690735"/>
    <dbReference type="HOGENOM" id="CLU_110781_1_0_1"/>
    <dbReference type="OMA" id="VNCKGRP"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="12201" checksum="8598C3EEA6957263" modified="2013-05-29" version="1">MSADDAHLQLLYQPHLAHNAASLSTLKWLCTSFAGSVAGVLGLENYWGFALFFASILLTTAVVWSIQCKGDVDRYVQGGWWEIINPGQENIASFILFWTLFYGLVHVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCS5</accession>
    <name>M5GCS5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_92416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633289.1">
        <property type="nucleotide sequence ID" value="XM_040777072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCS5"/>
    <dbReference type="STRING" id="1858805.M5GCS5"/>
    <dbReference type="GeneID" id="63692134"/>
    <dbReference type="HOGENOM" id="CLU_1111363_0_0_1"/>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="28595" checksum="15162887548E6E34" modified="2013-05-29" version="1">MNRAVTYYEVSAPSTVPKTPKWRRHSFTTSDGYKELRHVAVDRLKTDVDLCQALLDMRQREDALLHTLATLRSIVYAQRDATAAVRGDLKDQRAKLDSLRDKARQLIVDPAIRRRPGDGIEPTLLRIQRVGDELGRLKYTYEVTDDRLREVEGMVWGLTRRINDSGVRDMLEEEEHKQRAKGVGPDGRKLWMKGGQRLRSRLVDWAMWSGNLWSWLTRRKVEVIPPSGAGTPTHGRSRAPSLTLTLPHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCT0</accession>
    <name>M5GCT0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_89000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628850.1">
        <property type="nucleotide sequence ID" value="XM_040776887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCT0"/>
    <dbReference type="STRING" id="1858805.M5GCT0"/>
    <dbReference type="GeneID" id="63691949"/>
    <dbReference type="HOGENOM" id="CLU_003896_4_1_1"/>
    <dbReference type="OMA" id="VSWLPRQ"/>
    <dbReference type="OrthoDB" id="610608at2759"/>
    <dbReference type="UniPathway" id="UPA00771">
        <property type="reaction ID" value="UER00766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="25"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="469" mass="53145" checksum="DA80DE701E73ADC3" modified="2013-05-29" version="1">MIDLCHILDPISCKTGVFTNWAETYSCRPLSIFEPQTAFQCECIVELGKREGRQLRVAGSGHSPSDLTCTEGFMIKTDRLDQVLEINESEKWVNVQAGAKLHQIHAVLGEHGLAMSNVGSISEQAIAGIICTASHGTGWNFKPMSSSVLELEVLLADGSRVVCSNENNIGLFKATLCGLGATGMILRVKIQVEDAFRLAEKKEAVPFGSVIGDLENIAKSGEHVRLWWYAQADEIHVMRADRTKDAPNPPPHSFFWDRLLGFDALQLMLFLGLYVPSILPSVAQFACWLRRPHGTTVDDSWKIFNLDVFIKQYTAEWAIPQENAKDCIMALREWLREEHDNPRGLRPHFPLEIRWTDADDVWLSPSYGRKTCWIGMIQFKPYGFDVPWKELFDKFDKIMYSHGGRPHWAKTHSFGPPQLRESYPHFDEFVNLLKEIDPNGMFRTEYVNRHMYGLPAAGKTAVELYESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCY7</accession>
    <name>M5GCY7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_114533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631026.1">
        <property type="nucleotide sequence ID" value="XM_040769839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCY7"/>
    <dbReference type="GeneID" id="63684901"/>
    <dbReference type="HOGENOM" id="CLU_2061407_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="12871" checksum="94647C8D5DA40F82" modified="2013-05-29" version="1">MDSDDIDGGTWGSGVSASDRDQRSTQPLLPFGGMGGTTTEEVERGRSCYGTRAEQVILLQHPLVSPVSVQVRRLDDAQISHTARGETCNTPTPRSQRTARLDRIFPRAFVTVAALADLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD21</accession>
    <name>M5GD21_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633464.1">
        <property type="nucleotide sequence ID" value="XM_040767771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD21"/>
    <dbReference type="GeneID" id="63682833"/>
    <dbReference type="HOGENOM" id="CLU_927559_0_0_1"/>
    <dbReference type="OMA" id="MARNGMG"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="29818" checksum="B4ED9615F0F2932F" modified="2013-05-29" version="1">MVFGRRREPLANATNYPVGTGAAVNDPVMTDNDPYLAGGKRHSLFGGRRNRNSLTNPPPADAVGNPAYGAGQGTAANDNYGGASGTGMARNGMGTGAAMGTGASMAGPRTDPQTGVTIPGSAGVSGPTTTASGHPVTPTSSNARSLRKSGKMDSLMGTLFCSQRLKMEGEMKQEQAHAMAYQAAELNEANRLEEEATARRERAVAHGAHPAHGTLGGADQGVGMGMAGGGLGTGAAPGTTSFGRTGNLEEPGMAGVGAYGVGPGGYQPLAAPGAGMSGTFGHGPMGTTAYGETAPVNRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD39</accession>
    <name>M5GD39_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_29757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633484.1">
        <property type="nucleotide sequence ID" value="XM_040774322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD39"/>
    <dbReference type="STRING" id="1858805.M5GD39"/>
    <dbReference type="GeneID" id="63689384"/>
    <dbReference type="HOGENOM" id="CLU_020826_2_0_1"/>
    <dbReference type="OMA" id="TAETWAH"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="12"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="386" mass="41566" checksum="4391E0BB104B5022" modified="2013-05-29" version="1" fragment="single">MSSLPPELVLCVFIHGFKGTDGTFCGFPERLKHVLNETLQGTKVECVVFPSYETRGDLAEATARFVSWLTELTVNLESSHNLRAGGAKVVLCGHSMGGLLAADALLGIAGAESKDADRQGKMIWPRIVACIGYDTPYLGLHPNVFKHSMNQMNTYIDAAKAVASEFGLFGLAASPVPTSATGASPQAQAQAQASGQVQKHARAQSEGQRPGSRTEKERLLAPPPYTPTPKPLDTSSWTKQLSSLSISPTYVAAAAGTLLAGAAAGTAYYKRQDLAGGWQWASEHLQYVGNLWDEKGLKRRLELVISTGVVFRDFYTLLPASALHPTERTFSILPPSSSPSHPHFVPQTNKVAKDEIEAHIGMFEPKSNDGYYEMGLEVVRVIGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA8</accession>
    <name>M5GDA8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_103628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633574.1">
        <property type="nucleotide sequence ID" value="XM_040767792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA8"/>
    <dbReference type="GeneID" id="63682854"/>
    <dbReference type="HOGENOM" id="CLU_001265_23_3_1"/>
    <dbReference type="OMA" id="AAFNILW"/>
    <dbReference type="OrthoDB" id="2105912at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="47"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="481" mass="52033" checksum="469B09555AA4A8BC" modified="2013-05-29" version="1">MIAGADADKGDSSTNSAQEHNRDFGVFPIPHQLRHDTARPFEFSLLLNIVFAVTGTFTGANLYYCQPILIQLASAYQVDYDRIANVPTLTQAGYAAGLLLVTPLGDMVRRRELLFALLFCAGSVTLGLALTQSLVAFETLSFIAGLVAVTPQIIMPLTVDLAPAHKRGTALSIVFEGLLLGILVARVLGGVIAQFSYWRNIYWMSMGIHYSLLLILYFILPDVPDKKLGLSYIQILYTVLKFAVTEPVLIQSAIIGLCVNAVYASFWVTLTFLLGGSPYYYSTLDIGLFGLVGILGVATGPLVGKIVDRLNPWFGVLFGILGLMLTFAIDTAAATRSIGAIVVVAFLIDVFDSMQQVSSATRYFAINADARARINAVYIIAIFLGQFIGTSAGTRIFTAHGNYANGGMNLAWVGLALVVLLARGPVATTWLGWSGPKERWLRDQKSDQSDGKSLKALHDAEPPEPMVPITVAEPEINTETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDQ0</accession>
    <name>M5GDQ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FUN34 transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_99693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629502.1">
        <property type="nucleotide sequence ID" value="XM_040777614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDQ0"/>
    <dbReference type="STRING" id="1858805.M5GDQ0"/>
    <dbReference type="GeneID" id="63692676"/>
    <dbReference type="HOGENOM" id="CLU_051062_1_2_1"/>
    <dbReference type="OMA" id="GIYMAIW"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="25591" checksum="90582D47B8CA36C8" modified="2013-05-29" version="1">MSQEKNLKINTDDSEGSYEPHTPGGHAADASQPTMPVYHRQYGNPAPLGLLAYGTVFLAASLFNINARGIHNGSLVLLFAMFYGGIMQTLVGMWEMFLGNTFGATVFATYGGFNMSYGALYLPGVGVQALYTDANGVLSPDFEQAVGIYLLIWDVITLLFLIGCLRSSAPVVWTFGTTVVALTLLAANSFTGIQSLAVAGGVFGLCAAAGAYYAALAGFYSPTVTFKWIKLPPMSLAYSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDU7</accession>
    <name>M5GDU7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_51047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629587.1">
        <property type="nucleotide sequence ID" value="XM_040775026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDU7"/>
    <dbReference type="STRING" id="1858805.M5GDU7"/>
    <dbReference type="GeneID" id="63690088"/>
    <dbReference type="HOGENOM" id="CLU_004966_1_0_1"/>
    <dbReference type="OMA" id="NVKICAV"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="256" mass="28621" checksum="B60B283303EBA2ED" modified="2013-05-29" version="1" fragment="single">ITDGITIGHPCCSVHNCSEDLPAITARFCNTHKELQNICSIQGCFQPVQQGCLTCSDPEHLYVQTMYEERGKSMLHLTHCLAAHTTIQPSTLLLETGHSKLGQSWTHNEQLIVCPCGIIVAHVTLFGGEAISSVADMLQVVFPMKTSVPDVLFYDNNCHLHCHLAAQGDQHFTGMVQPVNMFHFKSKHSENDAYCGQHCNLLLFPALYNVTTKSWVFNSSAAEQCNVWLKGYDAMVHDLDATCFNFFLDEMIKERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GET8</accession>
    <name>M5GET8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_92905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632566.1">
        <property type="nucleotide sequence ID" value="XM_040777113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GET8"/>
    <dbReference type="STRING" id="1858805.M5GET8"/>
    <dbReference type="GeneID" id="63692175"/>
    <dbReference type="HOGENOM" id="CLU_030671_3_0_1"/>
    <dbReference type="OMA" id="LHYRADG"/>
    <dbReference type="OrthoDB" id="7108654at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="215" mass="23726" checksum="6B18722211FB19EC" modified="2013-05-29" version="1">MKDIVDLSHPMQMGMQIYPGDPKFICYPAAELSRNGYNVQRLQMGSHTGTHVDVPYHFFADGKKIDELPIELFVGRAAALDMSYKGAKGKINWEDMAIFEDLLKPGNIVLIRTGWSQYWGQNEYFDHPYLTRAAAVEILKRGVKVIGVDTLSPDATLDGAGDFGVHDEVLGSGGVIVENLNNLAAIQEGEWMVSLVPLRLAGCDGSPVRAFAWKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEV2</accession>
    <name>M5GEV2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_41033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632601.1">
        <property type="nucleotide sequence ID" value="XM_040774499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEV2"/>
    <dbReference type="GeneID" id="63689561"/>
    <dbReference type="HOGENOM" id="CLU_2203190_0_0_1"/>
    <dbReference type="OMA" id="PHFLANV"/>
    <dbReference type="OrthoDB" id="4085451at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="108" mass="12054" checksum="8966280CC2A2A45A" modified="2013-05-29" version="1" fragment="single">AVIKQDAQDPHLLSQLNRIGPVTVNPQNMPFQTAQSARIAKIFQTRQATEEASEVPQRNRLPVQAVTDMLNERKSAKTQADLANLAKDYSVDVEVLNRLAERFNSPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF68</accession>
    <name>M5GF68_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630787.1">
        <property type="nucleotide sequence ID" value="XM_040777587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF68"/>
    <dbReference type="GeneID" id="63692649"/>
    <dbReference type="HOGENOM" id="CLU_1194847_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="232" mass="25032" checksum="DCB9ABB8D91035CF" modified="2013-05-29" version="1">MATSRSMDSSYSSLFTQGLLNSSTPRASLHLPLPAFPTKSHSLPLAERRRTPPPTPLIIPPARVTPAKQSPHTFSASRKTPRSTCAGARRRSSVSSPAHALLKSPTRAELLRTRELHLIQAKTSRRSHGENMALLRDEASAGGRMSSVWTAPAAVISRLRRRALPISAPSPPPMKPLPALPGQNPADAYPSPLSLNIAVTYPSSATTPPLTIEIPQPKVESFSMEDEDEDMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFG1</accession>
    <name>M5GFG1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6 18">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 18">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_19494</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 18">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6 18"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633146.1">
        <property type="nucleotide sequence ID" value="XM_040771534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFG1"/>
    <dbReference type="STRING" id="1858805.M5GFG1"/>
    <dbReference type="GeneID" id="63686596"/>
    <dbReference type="HOGENOM" id="CLU_006714_0_0_1"/>
    <dbReference type="OMA" id="EDNEPHT"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000006">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000007">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000003">
        <property type="entry name" value="3-isopropylmalate dehydratase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012235">
        <property type="entry name" value="3-IsopropMal_deHydtase_ssu/lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001418">
        <property type="entry name" value="ACN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="19">
        <location>
            <begin position="13"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="20">
        <location>
            <begin position="538"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU06252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="760" mass="82730" checksum="26D1B17230A2E936" modified="2013-05-29" version="1">MPAPVLPPRTLYDKIWDDHVVDVQEDGTTLLYIDRHLVHEVTSPQAFEGLEKAGRKVRRPDCTLATVDHNVPTTSRKTFKSIKTFVEEPDSRGQCEALEENVKKFGLTYFGLADRRQGIVHVIGPEEGFTLPGITCVCGDSHTATHGAFGALAFGIGTSEVEHVLATETILQRKAKNMRITVDGELHEGVTAKDVILYIIGLIGTAGGTGCCIEYAGSVFRNFSMESRMSVCNMSIEAGARAGMIAPDQVTFDYLKNRPLSPKGEEWDRAVAYWKTLPTDEGAKFDIEINIRAEDIVPTVSWGTSPQDVVPITGTVPDPANFTDPMKQNGISRSLKYMALQPGTLMEDIKVDKVFIGSCTNSRIEDLRSAAKVVLAVKDAKVADTVNAMIVPGSGLVKQQAEAEGLDVIFKRAGFDWREAGCSMCLGMNPDQLKPGERCASTSNRNFEGRQGPGGRTHLCSPAMATAAAITGHLTDVRKLMGGASTTGVTSVEQIKQTNSKDYLTDPVLPPPAPQPETVHHNTVPSGTPAVHESKVHKFTVLTGITAPLHMPNVDTDMIIPKQFLKTIKRTGLGNALFHTLRKDPATGKETDFVLNKAPYDKAVIMVCDGPNFGCGSSREHAAWSLMDFGIHAVIAPSFGDIFRSNSLQNGLLPVQLSQEECSQLCADVEAGGQLEVDLEKQEVRRPGGKGAFHFDVDPFRRYCLLNGLDDIGLTMQKADKIEQFEERRSEAWPWLDGFGYVKSGGRVDAASKGGKKMDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFH4</accession>
    <name>M5GFH4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631032.1">
        <property type="nucleotide sequence ID" value="XM_040772069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFH4"/>
    <dbReference type="GeneID" id="63687131"/>
    <dbReference type="HOGENOM" id="CLU_2133420_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="113" mass="12986" checksum="DA013C21A8EC3771" modified="2013-05-29" version="1">MQRSGIDTATRLYHLPTSCTFLAAVHYAAEYADGKTKYSHENTGDPMPTDYEVTLLKAYAARIIRRHALVMMDNGHEIQAALRPARMVVELKLAPEMRRRRIWWSPLEATQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFJ0</accession>
    <name>M5GFJ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_63803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631057.1">
        <property type="nucleotide sequence ID" value="XM_040775740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFJ0"/>
    <dbReference type="STRING" id="1858805.M5GFJ0"/>
    <dbReference type="GeneID" id="63690802"/>
    <dbReference type="HOGENOM" id="CLU_013023_0_2_1"/>
    <dbReference type="OMA" id="ESIMRHY"/>
    <dbReference type="OrthoDB" id="5419821at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="GmrSD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="GmrSD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GmrSD restriction endonucleases N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="360" mass="42214" checksum="7DC9BC6D5A9FBCF4" modified="2013-05-29" version="1">MTASDLHALIHDGFIDLEPEYQRDVVWPEKKQIMLIDSMLNNFYIPAVIFSIRKEWSKEKGMELERRVCMDGKQRLTSMVRFMDGLIPYIHGNGIKYWYNLPNGETKRNQQLPDRLKREFDGKPISCIQYQDISEDDEREIFARVQLGVALSPAEKLQGMSSPFAAFVRQLQKQYIDADGTLGDAIKWQKKRGVDFACVAQIVFALYHLPNFTWPGLSKLEKFLKKKEVPTKTFKLEVLQIFSNYVALATDPRYYYGFQGIGDRVSPVEMVMIGLLLGYMKDYKSEDKAYHIKQLRLETRKQFKDIRMNDRVTKFMWSYIQSIKVPTKYVPSREETSSVSRKRKAARADENEFRPHKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFN9</accession>
    <name>M5GFN9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633371.1">
        <property type="nucleotide sequence ID" value="XM_040771587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFN9"/>
    <dbReference type="STRING" id="1858805.M5GFN9"/>
    <dbReference type="GeneID" id="63686649"/>
    <dbReference type="HOGENOM" id="CLU_066901_0_0_1"/>
    <dbReference type="OMA" id="HVCVFQT"/>
    <dbReference type="OrthoDB" id="269496at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="13"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="206" mass="22553" checksum="19C1A15834051B45" modified="2013-05-29" version="1">MAAAAAKIVAARTAFLLCDLQTAFRTAIYSFDDVEATAGKMLRAAKIFEIPVLLTEQNPKALGTTVATLPLEALHDSKLLHGPWPKKKFSMVIPELQACLKERGVQDVVLFGIESHICVLQTALDLLRESYSVHVLADGISSCNKGERSIAISTMREAGARVTTSESVLYQLMEDASDPRFKTFVTLIKDEKARTQQTSANLLEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFU6</accession>
    <name>M5GFU6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_44589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633491.1">
        <property type="nucleotide sequence ID" value="XM_040774593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFU6"/>
    <dbReference type="STRING" id="1858805.M5GFU6"/>
    <dbReference type="GeneID" id="63689655"/>
    <dbReference type="HOGENOM" id="CLU_000288_118_0_1"/>
    <dbReference type="OMA" id="MPYHRNQ"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="101"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU06597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="563" mass="63504" checksum="0F9785615868D3FC" modified="2013-05-29" version="1">MTTEDLFVAIPEGSEGYEDVPADVAYDGGEIDEDNEVPQSDPVWASEEGSHDQQMWNETDEPADEDEEELSFLMRPPSEQAEILAEIEDVERTMPRLSEDYRLVDRLGEGTFSSVYKAEDIKYDEHLNSYWLGYHPRWSSAYYQTLPPQKTSRGKAYVAIKRIYVTSSPARIENELLIMEELRGCRHVAQLMTAFREEDQILAIMPFHRNQDFRSFYRVLPLPKIQSYFRCLFRALKDIHARNVIHRDVKPANFLFDPAAEVGTLCDFGLAQRTSSPKLKCLHSSPTTTHPHGRFSWQDTSGQRSDKLAKAKQQYLNAPKRIAQGPEKVGYPTQDERPSVRANRAGTRGFRAPEVLLKCPDQTLSAIDVWSAGVILLSFLTGKFPVFNSNDDVEALMEIAAIYGAESMAKCAFLHNRTFLTNVPSADHSGTSLSELVRKLNPSLFITPDVDQTLLAGALDLLPRLLHLDCTHRITSANALEHSFLADPKIPERTVVPHVIGQGVCGHAHWQDDMDESHCVRVDGKIVRLRAGEGIPIGEDPCEIHKDWWTDEGPGSDHGRYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG59</accession>
    <name>M5GG59_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="5">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF6</name>
        <name evidence="6" type="ORF">DACRYDRAFT_20504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <text evidence="5">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG59"/>
    <dbReference type="STRING" id="1858805.M5GG59"/>
    <dbReference type="HOGENOM" id="CLU_071894_0_0_1"/>
    <dbReference type="OMA" id="WCAFCGM"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="245" mass="26436" checksum="9F9552368B5F887A" modified="2013-05-29" version="1">MAVRTQFENSSEIGVFSKLTNSYCLTTIGGSTNFYSAFEAELGDVIPIVQTSIAGTRIIGRLTAGNRHGLLVPQTTTDQELQHLRNSLPDTVALQRVEERLSALGNVIACNDYVALVHPDVDRETEEIIADVLKVEVFRQTIADNVLVGSYSVISNQGGLVHPKTSIQDQDELSTLLQVPLVAGTVNRGSDVIGAGLVVNDWCAFVGLDTTATEISVIEATFKLQGQETSAVITDMRDSLIDTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGI7</accession>
    <name>M5GGI7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632452.1">
        <property type="nucleotide sequence ID" value="XM_040767870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGI7"/>
    <dbReference type="STRING" id="1858805.M5GGI7"/>
    <dbReference type="GeneID" id="63682932"/>
    <dbReference type="HOGENOM" id="CLU_129959_0_0_1"/>
    <dbReference type="OrthoDB" id="3034157at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="177" mass="19945" checksum="000038FFDCAADF9B" modified="2013-05-29" version="1">MPHERQHTTLPAIAYQHDEIGHGCYHPRPAEQEEEDKEDEEDEAQEEEDKAQDEAQDEAQDKAQDEQVQLQVQFPDDGEMLLVGARPAKGKEKRKEKGSKAAAKPKYKGLHFGRCRTHNKQLVVHPCSVILAWATFYGSEGMSSVAPFLMSVFPTCKAMPEVLFFDNNCTLGQYLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGP5</accession>
    <name>M5GGP5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent RNA helicase SUV3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632742.1">
        <property type="nucleotide sequence ID" value="XM_040771847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGP5"/>
    <dbReference type="GeneID" id="63686909"/>
    <dbReference type="HOGENOM" id="CLU_2190149_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent RNA helicase SUV3 C-terminal" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="12338" checksum="285D14AC7143509D" modified="2013-05-29" version="1" fragment="single">MASPWPKRSIWPLVAASADDLLAAYITNPEIVQIQPVLEKHGLYDPFTVIHLGKKTIKAGQAGPAMQRLLTNPRTLVYLESAHRVVTFYLWLSYRFPVSFGEQLKAFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGQ9</accession>
    <name>M5GGQ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632812.1">
        <property type="nucleotide sequence ID" value="XM_040771856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGQ9"/>
    <dbReference type="STRING" id="1858805.M5GGQ9"/>
    <dbReference type="GeneID" id="63686918"/>
    <dbReference type="HOGENOM" id="CLU_950018_0_0_1"/>
    <dbReference type="OMA" id="YGSKGPQ"/>
    <dbReference type="OrthoDB" id="2563669at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="293" mass="31038" checksum="B4AD45AE1604E92C" modified="2013-05-29" version="1">MVNITLDDTSPFISYSDGWGVQSPQDPNLEYYLQETYHGTQTIGSNATIVFSGSGVYLYGSMGPAHGNFEVSVNGARQTFSGYSSTPLFQQCLFSSMLDASYNEIILINIGGSGGSFMDLDYIITTVPENTTFPAPPSLAPITPSGGFPSASPTSTSSSTGGSSLSTASSSSTSTTVTTVLTIVFAILTVVLLSIIAFLYMRHRRRKQVEQEHLFRYGRGPAVSPSPQPDLMTNLHWTSQAHTQGPAGGGSPNMGYPPRQSPVTSSLGASYQLQAGRSKGKNPPSTFLPGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNG2</accession>
    <name>M5FNG2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624288.1">
        <property type="nucleotide sequence ID" value="XM_040774032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNG2"/>
    <dbReference type="GeneID" id="63689094"/>
    <dbReference type="HOGENOM" id="CLU_131088_0_0_1"/>
    <dbReference type="OrthoDB" id="2574468at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="166" mass="18162" checksum="5CB75EC9E8D7E34B" modified="2013-05-29" version="1">MVPSLKRKSTDDEVERPNKTAKVDLSASVLFSVLPQCLQMEETMDVDMDAEAMTPVSADSSPVTHHAPVLPSYPHLQIYTPLKSFESSPPIDIPLVQSPFFESVPVTPSDQVYPEKSVQLLRPLISPTSSCSCERIPKLQLSCKKPNGNRSLWSYCDSCGAVGIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNP9</accession>
    <name>M5FNP9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_111296</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RRP36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624678.1">
        <property type="nucleotide sequence ID" value="XM_040769205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNP9"/>
    <dbReference type="STRING" id="1858805.M5FNP9"/>
    <dbReference type="GeneID" id="63684267"/>
    <dbReference type="HOGENOM" id="CLU_048802_1_0_1"/>
    <dbReference type="OMA" id="HMKSKQR"/>
    <dbReference type="OrthoDB" id="448446at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 9" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="161"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="310"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="368"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="449" mass="49538" checksum="11114B8B9595DE42" modified="2013-05-29" version="1">MPRRPRPENRRPPKSVLENAAALKRNAKGQAAKAPSAPVVQQSLKRKRDDEEKEEEESDGGFFEDASDEKPRGMLRGNAVDEGDDDDDESDDDDEDIGFDGIDEDDLSEDDEEDAGLAMYEDDDMRDVGSADSADEGDDAGQLKKLRSNLSSLPLGLLAKAQNSLHQAESGSDAEDHSDDDSDSAPSEHGPGGKPVVKTGEKKVRKEIQHRSTKHAPTEATSKRPVPRLRSSLPSLAPQPRDPRFTTLSGTLSLPHVRQNYAFLSDVQSQEVGQLREAVKLAKRRLPSTPEEKRDEAEAELARLAGALKRAESVRESNTRQAHEASVLRKLKKEEMTKRAQGKGEWHMKRSEKKKVLLEAKFERLKEEGGQRAVGKALRKREKREGEKEKKSRPFVRGEAGEGRSEGREEEVRLDILGEAGLVVLVEVDLGVQGEADLEELGGEGEAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPV8</accession>
    <name>M5FPV8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624246.1">
        <property type="nucleotide sequence ID" value="XM_040769305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPV8"/>
    <dbReference type="STRING" id="1858805.M5FPV8"/>
    <dbReference type="GeneID" id="63684367"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF35">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="35559" checksum="6368C0A9165E0349" modified="2013-05-29" version="1">MSIPPLSLDTTLQGRSVLVTGANVGLGFSAALLALQLGASPVYITCRSAEKGNKARDELVADPLVKEKNPHAIVKAYELEMLTWDGVTSFAKKFLDDREVAGEGLDVAILNAAIVNLKYEVAPTGNEMVLQVNYLSTALLSLFLLPLLKKSTTAEHTARLTFITSGRQLFTPLKHCPPEDVNYLASLNAKNTFGVLDRYGLSKLLVVLFLRHICDNISSDKIIINNVCPGIIQTRLERKLPWIIAPIVGLFKTTVGNTVEKGAECYIAAVASVGPESHGLWYQLMRLKPYSDVVTGPEGKKIQERIWRETVELFQKVSPGADTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ04</accession>
    <name>M5FQ04_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623552.1">
        <property type="nucleotide sequence ID" value="XM_040767674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ04"/>
    <dbReference type="GeneID" id="63682736"/>
    <dbReference type="HOGENOM" id="CLU_940163_0_0_1"/>
    <dbReference type="OrthoDB" id="10403525at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="296" mass="33759" checksum="32EF61EA3435E081" modified="2013-05-29" version="1">MSFGTGVTGDARARDILVPEAGNIPLDQIRNPNEVLQFVIRRMAAAVRTNATREDLVAKHLVLKGLRQTIVPLPLSGQPNTSSKVEEQLDSSRREIHKVEQKLQRYYIEAEVGWRQLGLTFALGHLPSLAEVRDVEGVRVWIDGIKNDIGRYLEVRMQDDLRRAEARVVQAANAPRPRDDEMERRIFEISKAQEDIRIEQAKQRRLDNAGVLHRLEALEREMHDRRQMDADAHTEIESVTKRLTDLEDVFGYTRADLDTLIEKMDGMAAKEDRIDDVEKELRGIIDSAIAWLGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ26</accession>
    <name>M5FQ26_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_70078</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625833.1">
        <property type="nucleotide sequence ID" value="XM_040775916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ26"/>
    <dbReference type="STRING" id="1858805.M5FQ26"/>
    <dbReference type="GeneID" id="63690978"/>
    <dbReference type="HOGENOM" id="CLU_017408_2_0_1"/>
    <dbReference type="OMA" id="LNYVHRW"/>
    <dbReference type="OrthoDB" id="3944240at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="301"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="579" mass="64485" checksum="AA92748EC00DE0E1" modified="2013-05-29" version="1">MSDPGPAPVLAPPPGQQDDVYLIDPGYAMIFTYTWVSVAAAAILYRLPKLYRRMRHAWRRDGLQGWGLYEDLSPLAPEEEKEALIRGSAIKRTDSFRWVTVSTPVRLVRAGEALFRNTFGWEVKYLRLNVGQLFLLVGFTVTLLLCLTLNSELVLNSNRAGFMVLSLIPPVFLLSTKNSPLAFLLSIGYEKLNFLHRWGGRMMFLLAWVHGALWINNRLVNGQAYLLLTEDKERRGIATISVLTLIVLTSLRPVRIFAWQFFFTSHVALYVAWFVCLNYHTPYAIPWIYPALAFYGWDISVRLLRFRVKDASLLPIDDQMTLVHIPDAVGGWRGGQHVRLRILAGDLAFQAHPLTILNAPASRADTTRTQGMLLGARVNGDWTRALNKLGKTGAWVMLDGPYGGVCMNPKERVLLVAGGSGVTFTLGVMDELISAVEGGDRRLREIEFVWYIRSYDCVSWFVSHLQALALRAHSMSFLDLRVRIFLTCPCGDPPLLLSSIPDCAVSTSKPSMRELVLPLLEFELEDAEGVKPAMGGGVGVVVCGPERLVRHAQNAVARISPVGAARAGGVEIHAERFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ36</accession>
    <name>M5FQ36_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624406.1">
        <property type="nucleotide sequence ID" value="XM_040769260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ36"/>
    <dbReference type="GeneID" id="63684322"/>
    <dbReference type="HOGENOM" id="CLU_1570604_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="170" mass="18879" checksum="137384D56A654FFC" modified="2013-05-29" version="1">MPRVWKCSVLEEWRRDIEKCLGVRRNVGNDDDVVVLGERIHIILTKVMFSDEGNPRTKAIDPSQEPRSHMHVVFPEKLLDGPTDMDVRSRQTSRVVFADLISAASRHAGTKVPTPVQVVNPFSRKMSPKRETAKVALGRCDIYVESRGVLHRGSAVLPAGGCLGLVGENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ83</accession>
    <name>M5FQ83_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623702.1">
        <property type="nucleotide sequence ID" value="XM_040771425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ83"/>
    <dbReference type="STRING" id="1858805.M5FQ83"/>
    <dbReference type="GeneID" id="63686487"/>
    <dbReference type="HOGENOM" id="CLU_847368_0_0_1"/>
    <dbReference type="OrthoDB" id="3364670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="328" mass="37583" checksum="875852BD390005E5" modified="2013-05-29" version="1">MTLEFGLSKTSGILACLQEQQHELQGYGDALFANMRLDRAFLQLTGVSAQFLHYLLLAQEEKSNIRTRVVEHLGELSWLKHTRGRGHDPVGTKVQDAILKGWAPCWHAMKAAVEQHNCYIDLLMKIPIPGLVISLPKKLEPEDLKNLSEDHPLWQDVWWPMFTPPSLWEEEEGLLWECKNMEWWWIDEMKALMGTQARALDLPDKIALEQKAREDDWFQHHWHCPPLSPHQWRKIKDSLQTDPTADEPSANSTTPIILEWSEPLINQSWANTNGKNSSTSSASNPYEHVMANLDVMVEELGAVVIDKRDLRSEPEQDDVDSVSEVKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQK3</accession>
    <name>M5FQK3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624686.1">
        <property type="nucleotide sequence ID" value="XM_040773841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQK3"/>
    <dbReference type="GeneID" id="63688903"/>
    <dbReference type="HOGENOM" id="CLU_694488_0_0_1"/>
    <dbReference type="OrthoDB" id="3360997at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067144" evidence="2">
        <location>
            <begin position="21"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="397" mass="40637" checksum="98464153C9816471" modified="2013-05-29" version="1">MDTIKRAIFVAGLTATSVLAQCSAPEFFSSSQILAIGQRAFSVVTGGDGGCTDGGQSGNVFLVRPGDSSFSAIPMGFFDATSSTNPNNTILAPSVSNPGYGYRIIIGPDATSTPVALSPTFALVTADWQSQSFDGVALVFPNPQSDSTTWTSSGQQLIAYQAFENLGISSFTALLYNAEDVTQSPTTVTDSVPIPSIDQTTDEYFFQIQNSLPTGSNYQLVLVPSSGETDKVLSMSGLIQIQAGSGGPNPFPFTFTQVRTINGDAALPTATLIATVTSNSNASSAISTSASNTTSSSSTSTTTTSASSTPITIITDGTTLIITATAPPSPNAGLPSGSVGNNGTLPNGLSTSGAAPVSHSGGTTLALTLAVSQRWDDSRAHTRFFRCIVSSGLIANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQS9</accession>
    <name>M5FQS9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Malate synthase</fullName>
            <ecNumber evidence="2 8">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_23897</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the malate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 8"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626213.1">
        <property type="nucleotide sequence ID" value="XM_040773446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQS9"/>
    <dbReference type="STRING" id="1858805.M5FQS9"/>
    <dbReference type="GeneID" id="63688508"/>
    <dbReference type="HOGENOM" id="CLU_018928_3_0_1"/>
    <dbReference type="OMA" id="WHLPERH"/>
    <dbReference type="OrthoDB" id="186072at2759"/>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="10">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="9">
        <location>
            <begin position="157"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="11">
        <location>
            <begin position="408"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT99315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="521" mass="58131" checksum="AB98F8B34B20EE07" modified="2013-05-29" version="1">MSIPVLKIHTQLTSDQAFILSPPALNFLVALHRAFEPTRQALLAARKTRQAELDNGGTLTFLPETKHIRDEASWRGAKPAPGLQDRRVEITGPPERKMVVNALNSGAKTFMADFEDSTSPTFSNLVNGQVNLRDAIRRQIDFELGGKLYALVQNPAVLLVRPRGWHLDEPRVTYEGSPLSGSLFDFGLYFFHNAEELVKRGAGPYFYLPKMEHHLEARLWNDVFNFSQDYIRIPRGTIRGTVLIETIPAVFQMEEIIYELREHSAGLNCGRWDYIFSFIKKFRTNSKFVLPDRSSVTMTVPFMQAYVNLLIQTCHKRGVAAMGGMSATLPIKNDKVANDQAMAKVYEDKLREVKAGHDGTWIAHPATVQIALDVFNEYMPGPNQYYNYRADVKVKPEELINPQVPGTITLGGVRANVSAALAYCGAWVSGNGCVPIANMMEDAATAEIARMQLWHWVHHKATTEDGQVITAELVGKIIDEEGEKVPGVKADQVGIAKDYLKSQVNAKLASEFLTSDLMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQY7</accession>
    <name>M5FQY7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_71084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624916.1">
        <property type="nucleotide sequence ID" value="XM_040775933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQY7"/>
    <dbReference type="STRING" id="1858805.M5FQY7"/>
    <dbReference type="GeneID" id="63690995"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OMA" id="EEVAVPW"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="24"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="407" mass="45661" checksum="A5A03710461473B2" modified="2013-05-29" version="1">MILEAAPAIGEVGAGIQVTSNVSRLLIRWGLRKQLEALGVVPAGFCFRRWENGEMIGYTSFEHMFPDYGSHYYHLHRADFHRMLYDLVVDAGVEIRLGSTVVKIDPEIPSCTLQSGEVVKSDLIIGADGVKSMIREVVVGHEDKPVPTGDAAYRVILPTELLLKDPDLAPFVNEPQMTIWMGPHRHIVAYCVRGRRDFNLVLAHPDDGSVESWTAQGSADKMRKDFEGWEPRVQKLLDLVPSVLKWRLMDRMPLEKWVHDSGKVVLLGDSCHPMLPYRAQGAAMAIEDAAFLGNIFSRLEDKSQVPVFIRGYETGRYPRTSEVQASARLNQKINHLVDGPEQLARDTVMKTAMEKPGTNQDEWNQWSDKRKGDALYGYDADVAADQFWAETLAKDVQVKAANGHARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRN8</accession>
    <name>M5FRN8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3 14">2.4.1.258</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dol-P-Man-dependent alpha(1-3)-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_57430</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyltransferase ALG3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3 14"/>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625291.1">
        <property type="nucleotide sequence ID" value="XM_040775442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRN8"/>
    <dbReference type="STRING" id="1858805.M5FRN8"/>
    <dbReference type="GeneID" id="63690504"/>
    <dbReference type="HOGENOM" id="CLU_035382_3_0_1"/>
    <dbReference type="OMA" id="DWETYMI"/>
    <dbReference type="OrthoDB" id="20028at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU364047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT98393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="433" mass="48562" checksum="8F358E37DF8C437D" modified="2013-05-29" version="1">MSPRPSLDLRQPIQSLTTFLTHPAYFWHVAALLLLGDAVLTQLIIRFVPYTEIDFSTYVEQVAIYDKGERDYVLLTGSTGPVVYPAGHVYIHSFLSQISHAGQDQFLLQQIYGALYLLTQFLAMAVYRTAGGVPNWVLLLLAASKRLHSIYVLRLFNDCWNVLGMMGSILAFARGHYTVGSALFSLALLVKMNALLYLPAILLLLYQSLGVVGTLLQLCTLILPIQLLPALPFLLFSPYSYLTSAFDLGRIFLYKWTVNWRFVPEATFLSSQFARLLMTAHLGMLGVFLIEKWSKKDGGVMGLVERGLRRPFKPAQLVRPSSDYIVTLLFTTNLIGIVYARSLHYQFYSWYALQIPFLLWRTPFPVPLKLSIWAGIEYAWNVYPSTVPSSIILVAGNALILLGVFFGTSNGKEQMQPRIARDSAPAGADTKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR1</accession>
    <name>M5FRR1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_25048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624597.1">
        <property type="nucleotide sequence ID" value="XM_040773982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRR1"/>
    <dbReference type="STRING" id="1858805.M5FRR1"/>
    <dbReference type="GeneID" id="63689044"/>
    <dbReference type="HOGENOM" id="CLU_035750_8_0_1"/>
    <dbReference type="OMA" id="NTQVYGK"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000016">
        <property type="entry name" value="Proteasome subunit alpha type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="299" mass="32172" checksum="EC5CFA18416ADFBD" modified="2013-05-29" version="1">MFRNTYDSDNTVFSPQGRLHQVEYALEAVKQGSAAVGMRSKTHAVLLALKRSSGELASYQQKMFRIDDHVGIAIAGLTSDARVLSNFMRQQAMASKMTFNRPVPVNRLVSAIADRAQVNTQEYGRRPYGVGLLVIGQDQSGPHLYEFSPAGNSYEYYAMSIGARSQSAKTYLEKHFELFENASLEDLIRHGLHALRETLQQDKELTIHNTSIGILGPAGVNEQANIASLGKEGVFRILEGEVIQPYLDSMQPKEVPAPVTSVAAAAAAAAAAGAPAAPAAEAPAEEMPGGLPDDDVNMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRR7</accession>
    <name>M5FRR7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_24501</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625341.1">
        <property type="nucleotide sequence ID" value="XM_040773700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRR7"/>
    <dbReference type="STRING" id="1858805.M5FRR7"/>
    <dbReference type="GeneID" id="63688762"/>
    <dbReference type="HOGENOM" id="CLU_030571_4_0_1"/>
    <dbReference type="OMA" id="CKERARF"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT98443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="255" mass="28160" checksum="CF5217BC6FDB37F1" modified="2013-05-29" version="1">MRVVPVPNQADNYAYLLIDEATKRAAVVDPYDVSKVARYAQKEGVEIESVLTTHHHHDHSGGNLEYVREYPGVPVFGGSTAVPALTKKVADGDEFSVGEDISVKCLATPCHTQDSICYYATSKSKPEQAGLVFTGDTLFQAGCGRFFEGNAEEMHKALSYLGTLPDQTIVYNGHEYTNSSMKFGKHIEPENPAFGKLDNLVKTQEMTCGKSTIGDEKSWNVFMRLGSTEVQKATGETDKVTMMRKLREMKNSFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSD2</accession>
    <name>M5FSD2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_100904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627213.1">
        <property type="nucleotide sequence ID" value="XM_040767499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSD2"/>
    <dbReference type="STRING" id="1858805.M5FSD2"/>
    <dbReference type="GeneID" id="63682561"/>
    <dbReference type="HOGENOM" id="CLU_343230_0_0_1"/>
    <dbReference type="OMA" id="WERENLQ"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="3">
        <location>
            <begin position="467"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="797"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="825" mass="91669" checksum="4682E8E1F20F63E4" modified="2013-05-29" version="1">MFTLTFPSEPSFDGYRGHPGLARRHTHASGRRHPTALYEIEPELPYDIDYASMNRRPSAPASRTWGSAYQNCGYEDYDGYYRQPAAPHFGRRQSMNVFQLRGLIAQRQQQQLEEERQRQREQQRQRESERQRQIEQQRVHRQRQLARLERERAQVEKEISSAQLFASQQLASMFSAPDQQLHRQNAIRRKSEDERLAELEVERTRLLAKKAEREAQEAAETQRAQAIAEQERQAKIQKMKLVRERHEAERLAQAAAAGAQAPDEPETAEDFEQQRRNAQRLVVETFLGELLGRFIDFNDSTPDVPATTSTSVDVKGKGKAPEQPQPEVQPKQERKVRFRGEYAGPSYSQQEEAPPAPVQVAIPIPTPVPVEVPVIVETVPAPAVPIVADLDSPAMHVDVPPVEPIVSEPTRSESPARDLALQQVQLLLAKFESLTYAFAFPRVLTFAFLDTPELAYTAQNAPIHSYEHALNSLLQELDGIDSEGDKEVRRARRESVRKVEKELGWVEAEIRRAWERENLQEELLSSSESEVEAIEPIEQSVVEPTPAEVEITNGATQSITEPVSETVEPALTHADDRASTKALLNEFLTEDTVTAQVPGAGINDEPVVTTTTEETDKEATVEKTVEEPTAESDPVAAEPATEQAPLIEVAVDERGIGDHVVEHLAIEEPNVVKSVEIADTPESAIVDHHDDATIMTTEQFTAEPTNESTLVIPSVESSAGLVADSVGEPVLVKTEPRALQLAESATTPGVEEDHAPSTVGVVPLSEPVSENASPLLSRAFVPVPISDELSHKVQFEDEVLAQSSSPDIESSGKEEGKSDDEFELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT58</accession>
    <name>M5FT58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_109909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626081.1">
        <property type="nucleotide sequence ID" value="XM_040768966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT58"/>
    <dbReference type="GeneID" id="63684028"/>
    <dbReference type="HOGENOM" id="CLU_1147167_0_0_1"/>
    <dbReference type="OrthoDB" id="2884925at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="27495" checksum="E03E57F95C2B621D" modified="2013-05-29" version="1">MISIPAAPVWPNGTWTPPSTIRERCALRHELKREIELLPIEHMRSDTAYKLRLKLLRAQYESDSRLILAKRLQKHCQFWSIAGISTLPDELLCDIILIATEQSDFISKMTREFAHVAPLVCRRWRDVCATMPQLWSTLVISDTLRHPTCDSVGTQRWSNIVKELPRLLFRCQGAPVTFRFTTRDLDAQATIPTVFATLQTSLASIRSVDIQLSAPYVRDVSKCIATSLPALESLSIQNAGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT88</accession>
    <name>M5FT88_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795931">
        <property type="protein sequence ID" value="EJT96471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623369.1">
        <property type="nucleotide sequence ID" value="XM_040769488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT88"/>
    <dbReference type="GeneID" id="63684550"/>
    <dbReference type="HOGENOM" id="CLU_146837_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="18131" checksum="1395F7ECF27CE88E" modified="2013-05-29" version="1">MEAQLPSLHHVISESIAAVPLDHAHSDADRKSMILQHKDLSREMDEPMEVVSEMEEMKAELEQVTQELEEVQQRQKEQQQQQLQEQDSWQVWQQLQESLQLQQEKLWQAQEQEWQEKELWGEEDIFLEQENSLEQDTIMDVKVAAIVEQEGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTJ9</accession>
    <name>M5FTJ9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623469.1">
        <property type="nucleotide sequence ID" value="XM_040767675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTJ9"/>
    <dbReference type="STRING" id="1858805.M5FTJ9"/>
    <dbReference type="GeneID" id="63682737"/>
    <dbReference type="HOGENOM" id="CLU_319846_0_0_1"/>
    <dbReference type="OMA" id="WTHAIAF"/>
    <dbReference type="OrthoDB" id="3260408at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1048" mass="111487" checksum="92DF1E5019F11205" modified="2013-05-29" version="1">MSRQSSASVSTPPPPGPSGSLKEEIDEKKPLVDAKPTTRVTRKPLAGPEFSDNVTFATPKSKSPNAVAKSTTKLAPKRKGRPKVRPSLLSVLLRLSFLTLAAYTFLCPITSPTPNQPITGPCTLLARAHTDIYSPFISPHLQSAWSSVLSHPQGGPYAQHLENTFNYVAPYVSSTRSVARSRLIPVFDKAQELILQTFTEAHIAAKPHIDPYLTHVSDVVNPYWTHAIAFQRQHVGPRILALRAQTQYAIRTATPYALRARIALLQAYQKVKPHVYTAWLYIKFFAMKASVAIADVFDAHIKPQWDMIMKEVGHIQAGAGEKASPVIQQAHATFSVAAESAASMAAAAHTEAASVVSVAHSQAAGYAAAARESVLAAAFAVHSVASEYVSIVQDKLSSITSAAHATANAAAATASQEAADVITDEFVAVSASATQYASKASAVSSTFSIAASAVVDAASAVSDTQPQAASHVNEAAATSSPSAPENGASVAEVMSSSLSEHSFTPSSAMSHATAAAAPADDAELEAPAQIMFKAASMVSSAADVMPVASATSDDAGLVPTLLNEAYQSQAAFVASLAESSAAAAASVAGKLEQPFALHQDAQAAAELLGQTTPSEPSTEADDQAGGDEFECWFTSLLTDQTPDEVGTETVSTTPPIEAESPITVPDTSLPKYHPPTAEELAQKRKGIEDTHTKWEEMLHAIGQGAIERLQREIERARESSSDKLLGENGGDWGRDVATYEKDAGRVAERVEQYAHELHAEDRPAHEKTEMLLNVITKVRAQVERWASDIETKLKDWWVGSEAGIAADVDKARQDVMDIAHQAQNELGMQYAWLEDVTVQDWTRYHALVNEAKRYGKTYSDLMSLTEDSALYKALANLTAHIQDVLLGFEARLALIHPFADAPVSGADDADSLVSPDIAEEEAQAPLFIPGVTAQADALPYLQRSQEEVEHALKAANAASEFTSSITSTTSEHAVTTGSQVSNPVEAERGFSLVLDSVPSEIGQTFTQSTDSIKSPAEAETAPPVLDRASLSLTSVASSISDHLNRQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTS9</accession>
    <name>M5FTS9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_97537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795882">
        <property type="protein sequence ID" value="EJT96631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623529.1">
        <property type="nucleotide sequence ID" value="XM_040777464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTS9"/>
    <dbReference type="GeneID" id="63692526"/>
    <dbReference type="HOGENOM" id="CLU_1081919_0_0_1"/>
    <dbReference type="OrthoDB" id="10437799at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="28701" checksum="B02E0901C05EFF8C" modified="2013-05-29" version="1">MCYPLLLGIKYTSCQCFLPLRKEFVDCLSETCTSSLCHPYECVGYLCTCTRVWEGEQLRVVRWEEGVCAACWEGEVRPFSPQRIYHKRVLSPALHEMSARYSTMTPSYPPPTPTHSRPLTRPRAPFQTSRSSSQSSKSPTTPAPPPPPAANRSRLTPLSRNTSRTSGRSASLADYGYSFPPVPRLGEIREELSPPSSPSDDNDYGERMGAGAGVGVYKGDYEVRPDRKRRFGFGYVREAVERSLSSGQSGGRRWGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU89</accession>
    <name>M5FU89_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626651.1">
        <property type="nucleotide sequence ID" value="XM_040768956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU89"/>
    <dbReference type="GeneID" id="63684018"/>
    <dbReference type="HOGENOM" id="CLU_1885696_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="135" mass="14451" checksum="3EE7E2792B64E644" modified="2013-05-29" version="1">MLRELAQQVLLPPSTSLGPSSIPLNSILGVSIMADVVWGLTSPLGVHMHLTFALSALCTPMPIALFLKVFGMALTGLLVLIWVYVGGRMAVLAMGGSVVWAALLVEGEEVLVQDDVLREEMMHVGERTREGLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU98</accession>
    <name>M5FU98_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0183-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626666.1">
        <property type="nucleotide sequence ID" value="XM_040768959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU98"/>
    <dbReference type="GeneID" id="63684021"/>
    <dbReference type="HOGENOM" id="CLU_032056_0_1_1"/>
    <dbReference type="OMA" id="YRKNDQK"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="402" mass="44486" checksum="4CF4F71EBBC586DA" modified="2013-05-29" version="1">MSTIELDVRPGQGVGPFDIGASLWNVLDTLREGKAQFPQVEIKFDNEDKAPATSPIIITLPPHVSLLFTGRTQRLHTILLHPITPVPPYSGLRLTYKSQTISSPSQHFKRSDVNAVFGPTYKGKRRLIFPGIVFEFERAEGEDGEARRAGREEQVDRIVVVQREKERDGVEVDQEDGLRECQAMVGELKRADITMHQGVTLHFVPSLTSTTPPEPIRVTMHQTTAEDLLADLGPPLRVHYKTDERMSIHSAASGMEEDNNSYFYNYFQHGLDFLLDGETHRVTKIVMHSNVVGSALFQRYKRCPWQLIPAQPSGSPSSNDAASPVPITVASPPDTLIRYLSPLPLSNDTDSRTDAPPSMILDRASESRDGPLLVGQTTRLLGFDGCVLEVGDGGEILALVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUE5</accession>
    <name>M5FUE5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_81422</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626741.1">
        <property type="nucleotide sequence ID" value="XM_040776509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUE5"/>
    <dbReference type="STRING" id="1858805.M5FUE5"/>
    <dbReference type="GeneID" id="63691571"/>
    <dbReference type="HOGENOM" id="CLU_074407_1_4_1"/>
    <dbReference type="OMA" id="WQWFTRR"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047859">
        <property type="entry name" value="Ribosomal_bL17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="309" mass="34754" checksum="3339D58D83549146" modified="2013-05-29" version="1">MRHGKAHRKLSRPSAHRMLMLRNLVSSLLQHQQITTTLAKAREAQPLAEKMITLGKKGTLHARKMAEQFVLNPKDTLPLLFGPYATRYAHRPGGYVRIHKSGNRFGDNAPLAILELVDNPRDLRFAMTARAVGRETLGWRGLPGLDIAGEGQTREQEVVAREPDLAGKEVDRLLREKTRLNRAKVLRYRGKQGREELNAAARGYVDELLAQPEVLGGPRRLKPAPPDAPAGGAWVGKKVWAGERTTGMGTSRVGLGIALGTLGRRKWVKPVMRGWDKERERKVDSELDEMELLERREREVKRKEEGMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUG0</accession>
    <name>M5FUG0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Six-hairpin glycosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_91856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623774.1">
        <property type="nucleotide sequence ID" value="XM_040777027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUG0"/>
    <dbReference type="STRING" id="1858805.M5FUG0"/>
    <dbReference type="GeneID" id="63692089"/>
    <dbReference type="HOGENOM" id="CLU_024197_0_0_1"/>
    <dbReference type="OMA" id="KFHMEMY"/>
    <dbReference type="OrthoDB" id="3534988at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="72047" checksum="853E6F5517CA909E" modified="2013-05-29" version="1">MASNCLRTAYLSVIDRKAIVRQFNPVRNASNLVTPMQVGNGNFAFGTDVTGLQTFIPYAIMSSWGWKNDSLPPGQIPSEYHGVNWTTHGREVAYDMPDPNLPALSQWMIANPNRMNLGAVGLLWKGAGVTEDDLDGKRQEIDLWSGAMKSTMTYHEAEIEVQTSVHPSDDTVGIIITSDLIGQGEHGIFLDFPYHNGLSKFEAPLVGIWNATSNHTTSLSQGKNIATINHTLDGASYFTTLTWPGKTNVSVSRDSPEAHRYSVWPSTKGNKIEFSVTFTPQPVRQALDAKTVMAESSRWWHQFWSMNGFVDVITGSSDPRAWEMQRRIIVSQYNLMVNEAGKNPPQESGLTNNGWYGKFHMEMFFWHMSHWALWGKWDILNRALPTYARHPIFFAELDYRAHLTNETLQKWNANVTSTADFMADYSWWNTSTGVYDLGPPLYPVSENTPLNSTMNTAFELVYWHWGFEAARTWLMRQGQTPPDSWGHVADNLAPLPQYNGTYVIYEGIGDMWSVQEYKMDHPELVVDMTIMQQTTDTVWAEWNITDCWGWDFPMLAMNAARLGNPSKAVDWLLDELLTFDDAGMPTGGVKVPTPYWPGAGGFLYAIAFMAAGWDGAPNVSARGFPQDGSWVVNWEGLSPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUL5</accession>
    <name>M5FUL5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623844.1">
        <property type="nucleotide sequence ID" value="XM_040774138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUL5"/>
    <dbReference type="GeneID" id="63689200"/>
    <dbReference type="HOGENOM" id="CLU_723661_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="382" mass="42376" checksum="64C3A9BAB5D4C67E" modified="2013-05-29" version="1">MKCVPDVINYTSETTSSSRIRSRSTDRLGYTTLSVDDSSMFFNYCELTTRRPHTPATLARTRQPNLSLCQLLRLQLRRLPSSLASPEPITSIPPNDTSHTLILVVNVRLHGTFHPTSVIRVYDYSQLEPSVILLGPQCTSPVFHSDISDAAFWIRMILSITGCVHSFSILLGNLSDQLPCSGITRGSFPLYVVPRSSASLWNQLTARLVPSSLPQVYIFPPCPCTLPHFTVHRAVSGTTGAVEFCLPRFMPPLTNCNLYRLRSGLSSKLECNWLAGRYVVHSETSDTIFRVVVHFPSPLPIVTFSHQPLRFQKTRRSSSYGSLPRILNSPETRYTQDPVSHPPLADDHALAFLSIAPSMTILVQSYTPQSILGNISASTCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUR8</accession>
    <name>M5FUR8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623914.1">
        <property type="nucleotide sequence ID" value="XM_040774157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUR8"/>
    <dbReference type="GeneID" id="63689219"/>
    <dbReference type="HOGENOM" id="CLU_2542537_0_0_1"/>
    <dbReference type="OrthoDB" id="10391812at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="9076" checksum="E08B07C2C1C7E62F" modified="2013-05-29" version="1">MFARQVASRVIAQRAPMFARRSIHVARDVKPYGVLSQLPPNGLYMLFGTAAVSAVGIGAGVRAWLMTPEELSKARHGSSVFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUU3</accession>
    <name>M5FUU3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626182.1">
        <property type="nucleotide sequence ID" value="XM_040773435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUU3"/>
    <dbReference type="STRING" id="1858805.M5FUU3"/>
    <dbReference type="GeneID" id="63688497"/>
    <dbReference type="HOGENOM" id="CLU_012066_2_0_1"/>
    <dbReference type="OMA" id="QDRHEFI"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="94"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="622" mass="71397" checksum="D5068C9835F99155" modified="2013-05-29" version="1">MTQTHSQRGLALAAAIRAKQNWPVKLLDEQRGVDQKWANEGKLLHQIDPDDVDRTIRELKREASRILSLDPVIRNEINIPADTYDWTAIDADIEAARERMRQFKYAVREPALKEHVGVRTADDLVPPSLHRVLEGELNRLADVGVKDFHPGSDGKVQDLIHPSLYPYVRGITRILDTHHPLNHAEIFQTVTRYPVDEYSEGMTEHKSTYAWLPSLFAISDEGKVTIDSPINALGPRFEHPALYKALERLFELALPQIEESMFYQWKYETSPSFRRWEERSEERQSGDIKKLQEKIEEQKKEKSLENQTRAERERIMKDEMEWEKQGTGLGGLQEKSKFAGKKLKVIVKAANYVLLPGQEYEGSWHVEGAPHEHIRASLIYYYSCDADISDKGLSFRRLRTEEDQPNCAKEHGSDFDMWNQETDDSYTDYPSDIEDVNSYPYTLPRNIELGTVSATGIDTEGGTRTGRMLSFPNWLQHQVTGLKNTRAEGNSPAMRKILCFFVVNESWPTLENEVELHFPGFVYSGPHVGPNAPPVLTTANVLPQQRFRIFPYVYNVLDMVCKRTTGGRGLPIELAIYVCDLADAGMTRADAEEHRRRLMDDRKAADRKVNRVWEESYGLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVI2</accession>
    <name>M5FVI2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ser/Thr protein phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_107554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628718.1">
        <property type="nucleotide sequence ID" value="XM_040768498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVI2"/>
    <dbReference type="STRING" id="1858805.M5FVI2"/>
    <dbReference type="GeneID" id="63683560"/>
    <dbReference type="HOGENOM" id="CLU_014743_2_1_1"/>
    <dbReference type="OMA" id="RYEATIM"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF27">
        <property type="entry name" value="ACL091CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012903981" evidence="3">
        <location>
            <begin position="16"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="250"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="669" mass="72934" checksum="24DEFFC07925D349" modified="2013-05-29" version="1">MALLLSLSIAATALAQTPALPPYLQTASAAFTGQPYFPSSLFAEYWPGFEPTQTSVQPQPKITDPVSGTIYPMELTDPDTIPDANPYVIPPSLLFPDAVTGPLLPNMNLFTPGSLALAAQTLQSILEITNSSQIEGTCGKCLAALGVVKMLATTAPWEVSGVIIELCNIFGYKSYGTCAEQFAVITDGQIATQVLALADVTSQDGEYLCALWLGSSCSLPAVNTLDLTGYFASPKPANAAAPPPSGKRVRVLHVSDFHLDPRYSTYSEADCSSGLCCRSCSNNLASPNTTVFPAPRYGAFLCDTPYDLAGVAVEAIPVLAGAGPTGREFDFAIFTGDLVSHDNDHQLGRAYVEYEETSIYSMMKQIIGYAPLYPTLGNHDTWPQAYNSPLSLQPEYLANQFSWDYEHISALWAQQDWIDSTAYQYASVHYGGYAYTTWRGLKIISFNTDFWYRDNWFNYLNTSDPDISGQFRWMADELQASLTAIPRIVITEIFFGHTHEDEFSIFYANNGTTMSAETAVATGWTAPSLTPLTNLSSGFRAYDIDPVTFNILDSYTWFSNVTAAPALDNQSAVGATYTFEYSAREAYGANISWPVDAPLNATWWHLVTEQWEVNPSLVEKFTIYEGKSSTYTTNCTSTACVQSKICYARSGSVPLAGLCPYGSTYGSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY6</accession>
    <name>M5FVY6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627421.1">
        <property type="nucleotide sequence ID" value="XM_040771205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY6"/>
    <dbReference type="GeneID" id="63686267"/>
    <dbReference type="HOGENOM" id="CLU_980125_0_0_1"/>
    <dbReference type="OrthoDB" id="10520097at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067353" evidence="2">
        <location>
            <begin position="25"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="284" mass="30498" checksum="60091378767181A7" modified="2013-05-29" version="1">MATRPVCVLLLLLSLLSLPMSVASQRCTRPGYSTDPVCIHGANPYCDGTRCLYASCSAGYYASQVHEEGVIYDTQTANLCTRCPGQGQTTDAHGQTGLTYGIGECYIPCGPAKCYVPSSGGLSLTASQTGMTQCVNSRKGICESTCTVDGTLPIPDAYTLGTVCHKTRSKKRNLPLAPRASARHVKKSAIVPPDSLLQKKAVLPRPAPVAAVGHAGAGEKRRTSGERERERAKAEKKYKVKLDERETVQEPKLEKAAAMGAKLRGAASYEHEKGPYARALDYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW43</accession>
    <name>M5FW43_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626777.1">
        <property type="nucleotide sequence ID" value="XM_040768861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW43"/>
    <dbReference type="STRING" id="1858805.M5FW43"/>
    <dbReference type="GeneID" id="63683923"/>
    <dbReference type="HOGENOM" id="CLU_108110_0_0_1"/>
    <dbReference type="OrthoDB" id="162969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="25337" checksum="842E7501BC89FB46" modified="2013-05-29" version="1">MDAGIIQNFKANYKQAHCEQALDQEMAGVLDIYCIEQKEAMGLAWIAWEEVTVETIANCWHHTWIVSPCGPDGCLLPTEEPAALPEDYANDDNLCAAVEWLHILIQELQDHGILPEAHRMEVNEMLSFAAEENTAQELTDKEIIEQVQVPEESEAEEEEEEAHVEPVISHHQALESVRALSRYFLQREEPEFAQAYWLCPPMLCAICLSVVKNMLQTSITDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWG7</accession>
    <name>M5FWG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_117631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626932.1">
        <property type="nucleotide sequence ID" value="XM_040770423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWG7"/>
    <dbReference type="STRING" id="1858805.M5FWG7"/>
    <dbReference type="GeneID" id="63685485"/>
    <dbReference type="HOGENOM" id="CLU_028760_5_0_1"/>
    <dbReference type="OMA" id="LGGCQGT"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="71"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="483" mass="52971" checksum="F317B0C35214E2B8" modified="2013-05-29" version="1">MDPPAALATPPQASSSSPSPPPSAFVNPFEALVAGQTITHVPSFELESGHVLRDVPVAYKTWGRLNEHKDNVMVLCHAFTGSADVEDWWGPLLGPGKAFDYTRYLVICFNVMGSPYGSASPVTRNPDTGRSYGPEFPLTTIRDDVRLHKLVLDSLGVRSIAVVIGGSMGGMATLEWTLCTPPSYVRHIIPIATSARHSAWCISWGEAQRQSIYSDPSYADGYYTPDDRPETGLAAARMAALLTYRSRDSFESRFGRRAQGGGKAVVGLATPPESPRETGPETHLAVHNDGHKGSRRAQTPGAVAERAVEMISAADVERSIAIRPAPQIFSAQGYLRYQGEKFTSRFDANCYIHITRKMDTHDIARGRTDLADESAALAQVLKTLPPRTLVIGVESDGLFTPYEQREIAAHIRDSELVIIRSPDGHDGFLLEFEQLNTHILRFLKRELKEVYEAEPTYSGEERAGFGIEKSSLFGEAEADVARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWI0</accession>
    <name>M5FWI0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626942.1">
        <property type="nucleotide sequence ID" value="XM_040773288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWI0"/>
    <dbReference type="STRING" id="1858805.M5FWI0"/>
    <dbReference type="GeneID" id="63688350"/>
    <dbReference type="HOGENOM" id="CLU_582686_0_0_1"/>
    <dbReference type="OrthoDB" id="3261505at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067318" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="48931" checksum="99437842B695DDD7" modified="2013-05-29" version="1">MHRPSILLLLLISLGAVQGLSYVRDHTRPPREAPLPVAKRELSGGIAAAHVARNNAHHHGRMIRRRTVQANVERDIITSLFPPNPAGNAAPTPTGNATSTSSDTTSSSSSTTNSTIPTDSLSSTSSSSTTTTSTTSTSATTSTTSTNSTTTTSSTTSTTPTSSDTTLPQATAPAPDNNQDNQVSTQYQYVTTGSRPSISSSPTSSAGASGATTSSTSIAKNTLIAIIVIASVVGVSAAAFTIIRKWKFGPSSKFEERMQPIDFSPGGGMEEVEEKAHNRGTSGGSWEAGSGEKNDAGLAAGGSTYPDASPSEAYASYPQAHDYTSNGAYPAHDFTAGSTGEYGYSGQEQYGYADMQRGGDPHAQYYAEQQHYADPSHQGADLARGPSANYGQHAQYVQEGADLTRGPSANYGQHAQYAPEGADLTRGPSANYGQQAHYAQENAYAQQFPGYGNNGGYPSHGQQQFHGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN0</accession>
    <name>M5FWN0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629250.1">
        <property type="nucleotide sequence ID" value="XM_040770127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN0"/>
    <dbReference type="GeneID" id="63685189"/>
    <dbReference type="HOGENOM" id="CLU_804156_0_0_1"/>
    <dbReference type="OrthoDB" id="3413923at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="345" mass="38112" checksum="CB1F4EA02733ACCB" modified="2013-05-29" version="1">MQRRWRIPVEPTGFTSALTIDEDCQHAIWLYHVSHLDDEEFDMVKSTIMQLPLDAANSANSEAIRAIPVFWAKSEYPLLHCDIIAAKNPTQSILVAQKYSTLAFILQFGEEEGATTGISTRDSFPVTNELNPLPSEGCDDQSQESTSKDLAWSDPRGSNSWAMKNVKALNTVELGSVIKWGIDMRYCPSPSLARRRGTRVKLELNEMPEQYSSNASITQSFFFQAGDSAFGALVRGYGVPGLPSPSGYCVPGIGMLAGIPFDGYSLIYDIEEGEWPCEWSVDVSTRMDGSGILSPSTPIPPCCQINMDNMRGDRARALDQEDAVRFNDANKKIAALFRFGLNKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXB4</accession>
    <name>M5FXB4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_111096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625014.1">
        <property type="nucleotide sequence ID" value="XM_040769172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXB4"/>
    <dbReference type="STRING" id="1858805.M5FXB4"/>
    <dbReference type="GeneID" id="63684234"/>
    <dbReference type="HOGENOM" id="CLU_1992565_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="125" mass="13473" checksum="BDF4D3E8283DE983" modified="2013-05-29" version="1">MQNQPVSDEQPANDASGDRKGAPTRAVIAKKVGNSVDDLRNAIGHISPDDITQLPAVQDTRVPCRCSPHEIIQPYGSQTFDHPTDISKTTGKFSQSVAHKRTAIVANDLKRSNTPAPYLMNEGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXW7</accession>
    <name>M5FXW7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Transcriptional coregulator SSA1</fullName>
            <ecNumber evidence="5">3.6.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Immunoglobulin heavy chain-binding protein homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">DACRYDRAFT_23038</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with transcription factor HSF1 on chromatin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="5"/>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627522.1">
        <property type="nucleotide sequence ID" value="XM_040773065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXW7"/>
    <dbReference type="STRING" id="1858805.M5FXW7"/>
    <dbReference type="GeneID" id="63688127"/>
    <dbReference type="HOGENOM" id="CLU_005965_7_0_1"/>
    <dbReference type="OMA" id="VQRDIKH"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 20" id="KW-0732">Signal</keyword>
    <keyword evidence="11 21" id="KW-0346">Stress response</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067312" description="Transcriptional coregulator SSA1" evidence="20">
        <location>
            <begin position="41"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="625"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00062310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00068399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EJU00625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="671" mass="73721" checksum="D2AAD78AAE620313" modified="2013-05-29" version="1">MAVRRPARSPRTTRSVASYFTLIALVVLAILFFCPPSAAAQDDDKNYGTVIGIDLGTTYSCVGVQRGGRVEIIANDQGHRITPSWVSFSDEERLVGDAAKNAFHTNPKNTVFDAKRLIGRRFDDPEVQKDMKHWPFDITNKGGKPVIQVQHKTELREFTPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLTVLRIVNEPTAAAIAYGLDKRGGERQIIVYDLGGGTFDVSLLSIDEGVFEVLATAGDTHLGGEDFDNRIIEHFVKLHKKNTGRDVTQNLRAMGKMKREVEKAKRTLSNQMSTKIEIESFDEGEDFSETLTRAKFEELNMDLFRKTMKPVEQVLKDANVKKEDIDDVVLVGGSTRIPKVQQLLKEYFGGREPSKGINPDEAVAYGAAIQGGILSGEEGTEDIVLIDVCPLTLGIETTGGVFTKLIPRNTVVPTKKSQIFSTAADGQTTVLIQVYEGERAMTKDNNLLGKFELSGIPTAPRGVPQIEVTFEIDANGILKVAAADKGTGKSESITITNEKGRLSQEEIDRMIREAEDFASEDETLRKRVDALNQLQNTVWSMQSQLGDQEGLGGKLNDADTKTMTAALRDATQWLEENSSSATIDELEEKLQEIRSELDPIVAKLYQSGSDGAQEPFSSHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYB9</accession>
    <name>M5FYB9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_112683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795891">
        <property type="protein sequence ID" value="EJT96522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623420.1">
        <property type="nucleotide sequence ID" value="XM_040769469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYB9"/>
    <dbReference type="GeneID" id="63684531"/>
    <dbReference type="HOGENOM" id="CLU_2638022_0_0_1"/>
    <dbReference type="OrthoDB" id="29558at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="77" mass="8383" checksum="97C5F2F26ECFBE96" modified="2013-05-29" version="1">MAPRKRKNGEPATALVEKVEAHGTIEVTLAESEPVKINNAHLREVKDALDGALIERTRDAYPPGPVQAEPSTRRAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYJ2</accession>
    <name>M5FYJ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_108285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627837.1">
        <property type="nucleotide sequence ID" value="XM_040768622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYJ2"/>
    <dbReference type="STRING" id="1858805.M5FYJ2"/>
    <dbReference type="GeneID" id="63683684"/>
    <dbReference type="HOGENOM" id="CLU_035735_0_0_1"/>
    <dbReference type="OMA" id="PYESHAY"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="68"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="54277" checksum="5FDA4594A9182E01" modified="2013-05-29" version="1">MEGDLSLEQRISDEPSTDRTLGSANGHDAEADHLEPPASDADAAQETDSPTKGGYGGRWKAQREAKPNKVYIGGLPETTRDEDLQNCFGKLGNVVNIELKLGYGFVEFDNVKAAEEAVAKYNEGYFMGSKIKVEQSHGGGRTSKYSNDPGACFKCGQHGHWARECPNGGTSIPGRKYGAYGRQDSLLTRMNGTKDYGAPPRDAGRFDDRERYPPPPPRDGRYDYGRPPPPLRDTRDYREPRDIRLPPSPPRDYPREYVGAPPPRRDYYDDYRRPEGRAPPPAVPPPRYDARPYYPEAAYAPQAAGYPPRIPDYPSVARPPIGDPYAPRPYERRDSGPGVPPPPAGDKYGYPPVPPPGRPRSPPPVRTGPPRDDYERAPPRDYARAPDYRARSPPLSANSAARYPEYPPRDATANGYRRRSLSPRAGSYRGYPDPKTAGGVPPYPPTNGYSEQSYGGAASAGSRAPLPREALPPRDRDYRGMPPSDPNYRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYW3</accession>
    <name>M5FYW3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_60115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623575.1">
        <property type="nucleotide sequence ID" value="XM_040775615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYW3"/>
    <dbReference type="STRING" id="1858805.M5FYW3"/>
    <dbReference type="GeneID" id="63690677"/>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="IIWREAL"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="392"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT96677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="434" mass="49006" checksum="004E68F63AB30416" modified="2013-05-29" version="1">MSHRHIFNALNQTFIVDSEYDFVKELGQGAYGCVVAARHRRSGEGCAIKKITNINTKRILTKRCLREIRLLHHFRGHKNITCLYDMDIVYEPNGDYNEVYLYEELMEADLHAIIRSGQPLSDAHFQSFIYQTLCGLKYIHSAKGLHRDLKPGNLLVNADCELKIGDFGRARGWQPGLGIQQQNNRGQEGFMTEYVATRGYRAPEIMLSFANHGPPIDIWNVGCILAELLGGKPIFKGRECVDQLNQILHYLGTPSEDTLRRVDSPRAQDYIRSLPIKPRIPFQSLYPHANPLAIDLLSQMLCFDPAKRISCEKALEHPYLAVWHDTADEPLCSQTFDFAFEKVDDMPGMKQLIIEEVNSFRALVRSQARQQLQARKQDSLPIPIRDDILASPVNENEGTSGYTFPHPSAPGPSGGMVEEPGAELDKELGGYGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ72</accession>
    <name>M5FZ72_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAM1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Outer kinetochore protein DAM1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">DACRYDRAFT_115523</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630235.1">
        <property type="nucleotide sequence ID" value="XM_040770023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ72"/>
    <dbReference type="STRING" id="1858805.M5FZ72"/>
    <dbReference type="GeneID" id="63685085"/>
    <dbReference type="HOGENOM" id="CLU_066250_0_0_1"/>
    <dbReference type="OMA" id="YGLKMNA"/>
    <dbReference type="OrthoDB" id="5586015at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990537">
        <property type="term" value="C:mitotic spindle polar microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013962">
        <property type="entry name" value="DASH_Dam1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08653">
        <property type="entry name" value="DASH_Dam1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="111"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EJU03341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="29549" checksum="2669D519D836B55B" modified="2013-05-29" version="1">MAPPTSRTPLRRVSQSSLRDLHRSSLSQAHPAPTTALDFLAPVLSDLTDEADALQHNLEQLNGLYDALGTFNEAFASYLYALRMNAFCVEWQQAPSEDSFVRAKEAATRAAAALARQAHHPSSPTKDPPHGLSDKTRTTADNGNTTYATTVGSPNVSEVKIGIPKPGLKKRAPAKKMSPAEKKKRDADIEKIVVVMPIEYRGNDPDTRKLMEGVINKLMDAPNGLKIAELVKAPDLTQARVNKCLIALVSKKIVRKTSQNGAAMYIFTGVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ76</accession>
    <name>M5FZ76_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_116254</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628711.1">
        <property type="nucleotide sequence ID" value="XM_040770168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ76"/>
    <dbReference type="STRING" id="1858805.M5FZ76"/>
    <dbReference type="GeneID" id="63685230"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="HEPNWQL"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="490" mass="55435" checksum="952350C84779A19F" modified="2013-05-29" version="1">MREVRKDDTVLMKWSEEYGSTFGARVVLGNYKVYTVDPRALSHILNHTDIYPKPEYLQNILASMVGGRGLLLAEGEEHKRQRRIMNPSFSLGHIKEIMPIFFDTAHQLRDSLNSILAKVSESEGTEIDMFSWVTRAALDVIGQAGFGYRFNALHDESNELFCAVHDMIEAAGKSPLLGILMGRFQLLRHLPLEYNRKMTEARATTRRIGMALIRKEKAAVQQEMQGKLEKSNVGRRDLLSALIRANMSPELALHQRMSDDEVLAQISTFIVAGHETTASGLAWTLYSLSLSPRVQDKLRLELQQASEEAPCMEELSALPYLDAVLKESLRLWCPVRSTVRVATRADQIPLSTPLVDRQGRRHDYVQVQAGDVVGVESVVVNHAKEFWGEDAHEFRPERWEEGLEKVKEIPGVWAHTMAFLGGARACIGYRFSVMEMKAILFTLIRAFEFAPIEGQEIGMKDVIVIRPFVKEQKEKGIQLPLRVCKVHRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZI3</accession>
    <name>M5FZI3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_101582</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625874.1">
        <property type="nucleotide sequence ID" value="XM_040767569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZI3"/>
    <dbReference type="STRING" id="1858805.M5FZI3"/>
    <dbReference type="GeneID" id="63682631"/>
    <dbReference type="HOGENOM" id="CLU_000288_67_4_1"/>
    <dbReference type="OMA" id="KLRVDQF"/>
    <dbReference type="OrthoDB" id="18472at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05600">
        <property type="entry name" value="STKc_Sid2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000141">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000319">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000109">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF417">
        <property type="entry name" value="CELL CYCLE PROTEIN KINASE DBF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="140"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="441"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="546" mass="62211" checksum="13BF03718257E72F" modified="2013-05-29" version="1">MAAQTGAPGLSGAAQMVKDVHMSTAKGFVNLSTSPDIHMETARTLFSGRTGQALPFWQKEKLESAEVKRKATLAQMYFLDYYFQNLGYLAARRARRSKFDVDTAERQLPELEYITELKSYLSRERALLRRRRTRLRVEHFRIVAQVGQGGYGEVFLARKVDSGEICALKKMRKKTLQKMDEVRHVLVERDILTATRTPWLVALLYAFQDADHVYLAMEYVPGGDFRTLLNNSGVLKEEHARFYICEMFAAVNELHRLGYIHRDLKPENFLVDGTGHVKLTDFGLATGALNPTRIDSLRRKLEDARDDEIISRSTMERRSIYKSMRIQDPRYADSIVGSPDYMAPEVLRGKAYTYSVDYWSLGCILFEFLAGFPPFSGASSDETWANLKNWQRVLQRPHYDKPEDLIFNLTDTAWDAITRLIAPAQTRLSNLRDLAAHPFFALSPWSDLRSKQAPFVPTLDSDVDTGYYDDFTNADDMAKYAEVKEKQRNVESVQEKEEPGPRGVWVGFTFGKNGLGPRARGSQKELEAATRAVKDAFDEGHMATIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZJ6</accession>
    <name>M5FZJ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LsdA family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630350.1">
        <property type="nucleotide sequence ID" value="XM_040768118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZJ6"/>
    <dbReference type="GeneID" id="63683180"/>
    <dbReference type="HOGENOM" id="CLU_045147_0_0_1"/>
    <dbReference type="OMA" id="MVNGGAI"/>
    <dbReference type="OrthoDB" id="5293813at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067363" description="LsdA family protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="38930" checksum="EF3D7B069850EC3F" modified="2013-05-29" version="1">MFTQLLAAAFFGSAITAYAAPQPRDTNSSDPLPFPDGFPNPSDAQLQQIFIDAHGTLSNSTPPANISAQGLVNLRLLDFAERIEAVYFEEFLSNVTTGVAGYELPSWVDYNYFVNFLNVTQHVEELHNLDAVTALAHFNQTAIQPCTTYNFPVSNFNESVTLAMTFTSNVFGLLGEIAQIFAQNGDVGLTRHIVQIVANEGEQNGFFRYLLGKVPDELPFTTVSTREFSFTALQGFVDPTSCPNIDIIAADLKTFDALTLLDTPEAKTETIRFAVASDKYVNGTNYSVVYTNQLNVPVVEPATYVSADNTSVTLSATFPYDAQLLNGLTIAAVVNGSGPFADVDAVAAAAIWAPAFIVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZN1</accession>
    <name>M5FZN1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628866.1">
        <property type="nucleotide sequence ID" value="XM_040768517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZN1"/>
    <dbReference type="GeneID" id="63683579"/>
    <dbReference type="HOGENOM" id="CLU_1669339_0_0_1"/>
    <dbReference type="OrthoDB" id="3354877at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="158" mass="17622" checksum="33C4DEE9081C49A7" modified="2013-05-29" version="1">MHLPFLPAVHIVINFDGHKILHSLSVRWRAFKALLSLSAQVESTEREMRRAVKCVLQQAMQDGADKAEVGRMLAELAALGDRAARSAHNHSSHNPFRLAQVAQTRHNMKELENEVMLAGAVRKIRNIAAACRLGELDELKEPMVIAERAFRGDKLSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR5</accession>
    <name>M5FZR5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_59657</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the TIM23 complex, at least composed of TIM23, TIM17 and TIM50. Interacts with preproteins in transit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion inner membrane</location>
            <topology evidence="1 14">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the TIM50 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT97002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623900.1">
        <property type="nucleotide sequence ID" value="XM_040775576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR5"/>
    <dbReference type="STRING" id="1858805.M5FZR5"/>
    <dbReference type="GeneID" id="63690638"/>
    <dbReference type="HOGENOM" id="CLU_023309_1_0_1"/>
    <dbReference type="OMA" id="NLRQPYT"/>
    <dbReference type="OrthoDB" id="287041at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000019">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10 14" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="16">
        <location>
            <begin position="173"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="454"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00065975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJT97002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="482" mass="52343" checksum="692B6E3375992888" modified="2013-05-29" version="1">MATAQSGNGNGNGKKRKGQLGGRPNIPPLPKEPQAQATPAAEEASAQEPSAPTPTPAEAAAEAEPTALPSLDITSPSITPDQRTGAKAASTQTSIDRQRRTFARLWTGIFLLSAVGGVAYLSRGWTEAEEAAGVGEGVKDAWWARIWRRGGEAMDYFNRPQWKELLPPPLPFPHGRPYTLVIDIDDLLVASTWDRQHGWRTAKRPGVDYFLAYMSQFYEIVVFTTQYVYSAQPVLESLDPFSTFIQYRLFRESARTLPSGQLVKDLSYLNRDLSKVIMLDTVKDYAALQPDNAIVLPKWRGTPGDKGLVGLIPFLESIAIHKVPDVRPILHKYADQDIPTAYAAIEAAQKQKAVEEWNATHSSASGSMGSFTLSSMFGGAPAAPKMPMSYLEQKRAEAQAIYLEEQKYFKEHEGEMKRLMEEDRQRQLGEMRGSLLGYLGLQGPQAPGALAEGAGAATAPVGQGSTGQTPPVVGVAMGGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX1</accession>
    <name>M5FZX1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_38770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630460.1">
        <property type="nucleotide sequence ID" value="XM_040774449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX1"/>
    <dbReference type="STRING" id="1858805.M5FZX1"/>
    <dbReference type="GeneID" id="63689511"/>
    <dbReference type="HOGENOM" id="CLU_001324_3_2_1"/>
    <dbReference type="OMA" id="REECTID"/>
    <dbReference type="OrthoDB" id="3366231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="13456" checksum="157F2387ED0CAE81" modified="2013-05-29" version="1" fragment="single">LSQVGRCVILPSSFVSSGHFMYQLYQDSMAIVCWAGYPDIFLMLTANPKWCEIVKNLLPGQTAQDQPDLVAQVFHLKPNEVLELIYKGNIFGKAVVQVYTIEYQKHSLLHMHLLVFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G015</accession>
    <name>M5G015_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_72431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624010.1">
        <property type="nucleotide sequence ID" value="XM_040775967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G015"/>
    <dbReference type="STRING" id="1858805.M5G015"/>
    <dbReference type="GeneID" id="63691029"/>
    <dbReference type="HOGENOM" id="CLU_008479_0_0_1"/>
    <dbReference type="OMA" id="FNNTCIQ"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12565">
        <property type="entry name" value="RRM1_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="252"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="432"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="543"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="649"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="743"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="766" mass="84644" checksum="63A1D9363590064E" modified="2013-05-29" version="1">MSRLIVKNLPVYITDQRLRDHFSQQPFISRHAGPGGYTLTDARIARKPDGTSRKFGFVGYKTREEADRAREWWNRTYIDSTRITVEVVEENHEPRKRRAGDENDPPPRTTANGDKNLAAKHESKKDTQKDKFVNAMTSKSTTRTWADDLLPPPEPTNMEKLRTVDSVTVTSEENKNAQADGEPTTEGLSDMEWMRRRMTKTLDADAEWKGFEQSDDEDGAADQPNSGAIGVQEQSSKEAERHQTAETILSTGRLFLRNLAYTCTSAELQEHFSRFGEIQQVHLPLTPSRTPSGLAFITFADPSCALAAYEALDTSPFQGRLLHILGAVDKRPAASVTSAPKSLKDKKLDERKKSSGHGWDWAMLYLNPDAVAAAVAGKLGVEKSEILNAEEGNAAVKLALAETSVVQETKLFLESNGVDISAFSGRPQRSPTTILVKNLPAFTTPQAIRELFQPHGKLKSVVVPPSGAIALVEFDDESEAGVAWRNVNYRRFGGSIIYLERGPVGLWKPSGAAATAKGTGPEREDRVIVLPEDEQPPEAAPGSTLYIKNLSFTTASSTLSSLFSTLPGFVYARVQTKPNPKDPAGRLRMGYGFAGFGSREQAERARKAMDGATCEGHKLSVRFAGRGKEEDEQPAGPVGVFALGNKKTAKVIVKNVPFEATKADIRSLFQGYGQLKSVRLPTKFDRRTRGFAFLEFVSRKEAENVMAALKHTHLLGRHLVLDWADDEQGMDNLRERTKRAFGDGKEVPTKRRKLNIAEDMEEDGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0N6</accession>
    <name>M5G0N6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629206.1">
        <property type="nucleotide sequence ID" value="XM_040772633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0N6"/>
    <dbReference type="GeneID" id="63687695"/>
    <dbReference type="HOGENOM" id="CLU_2263634_0_0_1"/>
    <dbReference type="OrthoDB" id="354769at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045145">
        <property type="term" value="F:single-stranded DNA 5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11560" checksum="726A2F1582024D90" modified="2013-05-29" version="1">MVKQESLGGQAPDTPIARPVALPLQSKLDEAVILGCHRFSYSETQVDAHIDKMLALWTGDREPIGVDVEDVNRCWRCPYEEGCEWREMKAKEFTSKTGVHISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0X2</accession>
    <name>M5G0X2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_107526</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628687.1">
        <property type="nucleotide sequence ID" value="XM_040768493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0X2"/>
    <dbReference type="STRING" id="1858805.M5G0X2"/>
    <dbReference type="GeneID" id="63683555"/>
    <dbReference type="HOGENOM" id="CLU_000288_82_0_1"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="14"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="238"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="333"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="401"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="610"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="736" mass="79306" checksum="CA602579DDBE6773" modified="2013-05-29" version="1">MFPASEERIDRKYGKWGRVLGKGTGGTVRLIQGPPRSGGKVFAVKEFRKKKGKETEFEYRRMIATECCFANGLKHVNVIETVDIVRNKSRYFQVMEYAPYDLFSVVMSGKMVQPEVYCVFRQICDGVCYLHSTGLAHRDLKLENCVMTNSNVVKLIDFGTATPSFHPDKGLILSSGLVGSDPYVAPEVIRGEMYDARKADVWSLGIIFLAMMLRRFPWALADPRKDLNYRKFASTLHELPARPRTPPSPRRRVSTGIKSSANGTNGKGPANGTAANGTANGTIKLPVPKPRQRSAEEGFDSSASSGYDVPAPSLWGAGEGSITTFTSVESSLVLTPSDTGGSRASGPSAPDGEGNRDGEREGEEGDADADSLDGVEDDNDNWVEPRLESYENWEEVIERLCAERESSSSSEASSRSSLRSSLSPREVTRNGTGYVQPPSTGNGFLRPPEPHVRRETSEPALNVNGNSNGLRPPSGLQPNRLPRPAISTNFNFAPASGTLSAHPVLGEGLSASPLSAFPPKSAPPEQHPFAASSPTLPSQLRTLPALVFPHSQGQSQKGDEREQEPIIVSPDNTLSYLPAETRWSILCMLQIEPNSRCGIADLLYPTPAQAQREEKVPSGLQMTPARRATTPLTPTPTPAPAPAPTSAAGRRREKGIQEMGREWLKSVVPCSGHDQIPGTPGTARTPQAPTTARGNGIGIGIGEGAWGAGTGSGVGVGHVHVRLKTSQKEGKWWKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1A0</accession>
    <name>M5G1A0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PH domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_81999</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CDC42SE/SPEC family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626499.1">
        <property type="nucleotide sequence ID" value="XM_040776542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1A0"/>
    <dbReference type="STRING" id="1858805.M5G1A0"/>
    <dbReference type="GeneID" id="63691604"/>
    <dbReference type="HOGENOM" id="CLU_015385_0_0_1"/>
    <dbReference type="OMA" id="EYNQDRK"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008092">
        <property type="term" value="F:cytoskeletal protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035023">
        <property type="term" value="P:regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00132">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000281">
        <property type="entry name" value="Actin associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000010">
        <property type="entry name" value="Related to Neural Wiskott-Aldrich syndrome protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039056">
        <property type="entry name" value="SPEC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13502">
        <property type="entry name" value="CDC42 SMALL EFFECTOR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13502:SF9">
        <property type="entry name" value="CRIB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="14">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="13">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="238"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="263"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT99601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="338" mass="36057" checksum="805853CB43954428" modified="2013-05-29" version="1" fragment="single">MPGISSDDKAKIKSTLPTSTNKVSTAALARVYYAYPDPSYWSYAGFEGGLALVFDKGRNSNWFKLIDLSGTRGVIWEHELYEPFQYNEDRPFFYSFEGDECSIGLVFSDESEAKTMRKKVEGRAKSSKKAVAPVQQAAPVPSSPTGKKSKKKKGGKIDKSMISAPTEFKHLAHMGYDTQKGYSSTGVDPSWTTLLETLGNMGIGASSIKGNEAFVKQFVDARGGVDAFKQEAAVKAAQADEQRIKRKAPPPPAPRRQVTVVPPSEPTRAPPPPPPPTAPPAPPAVPIMAPPPPPAPPAPSVPPPSRAPPPPMSPPPPPTSALYPPPAPPPPPPPTMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1T2</accession>
    <name>M5G1T2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626749.1">
        <property type="nucleotide sequence ID" value="XM_040768855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1T2"/>
    <dbReference type="GeneID" id="63683917"/>
    <dbReference type="HOGENOM" id="CLU_1594483_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="167" mass="18239" checksum="806B5648EA9D9473" modified="2013-05-29" version="1">MFTSSAAQTSASSRSAKIARLQGHLPNAPSPTLLPNSLSLDILPPSPSWEGRFPCLSDDSLFLETCPGFPFPDPLFPAEYAYDALHPLLPAHSVPLGEASTTHICAMISRDAKRDFDRRQTPLSDRGPSRPSRRAYTPSTRMCPKPDAAKETTRVQRIQSGRAYSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1Z3</accession>
    <name>M5G1Z3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631095.1">
        <property type="nucleotide sequence ID" value="XM_040771032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1Z3"/>
    <dbReference type="GeneID" id="63686094"/>
    <dbReference type="HOGENOM" id="CLU_946721_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="294" mass="31945" checksum="8511C85F3333C780" modified="2013-05-29" version="1">MSGTEPMTMHILTRLSPLAGNGELDGIDNNEELGQACLDIMCAAHLPVDVSIAANVTVTPAIDVMEPSLAEHQGVPKGEHGAIQVALEPKDEEQLDGEPEVSSSTSIIDEEMLLLPHKEEAAHNAGDAPAPSVDSSLISNTSEPQPLLSLHTAEHDFPQQEHQPQPQPKTHPPVPIVQNPPQQQQVQPTAHSAMVLALEEHLRGLQLDDIEFWLLAAEHLKRGLTGDLDEIMGPAGRLAMEERQYSHFPRASERNQAHLTNQWDTGMSGASSAPERRAAVTLTPEEQLQQEICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G211</accession>
    <name>M5G211_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G211"/>
    <dbReference type="STRING" id="1858805.M5G211"/>
    <dbReference type="GeneID" id="63688313"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="WGQIGRL"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="39204" checksum="0AA63BA3A2964810" modified="2013-05-29" version="1">MAPQVEYRRLGKSGLRVSVPILGAMSFGSDKWDAAPWVINEDQALPLLKGAYDLGITTWDTSNNYSNGESERIIGKAIKHYNIPRSKLVIMSKCFNLVAEDMDGSVRTAWRPELKNQAKYVNQSGLSRTAIFNQVEGSLKRLQMDYIDVLQIHRYDPNTTFEETMEALHDIVKSGKVRYIGASSMWTWQFQQYNQVAEKHGWTQFISMQGHYSLLYREEEREMNKYCEYHGIGLIPWGPLAAGQLAKPVSATSLRVSSAVGTPFEMKKSDADKEIINRVEELAKKKGWLMAQVAIAWINTKVSSPIIGFSSVQRIEEAIIPNKTLTDEEIKYLEEPYKVKSISGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G267</accession>
    <name>M5G267_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_21745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629678.1">
        <property type="nucleotide sequence ID" value="XM_040772533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G267"/>
    <dbReference type="STRING" id="1858805.M5G267"/>
    <dbReference type="GeneID" id="63687595"/>
    <dbReference type="HOGENOM" id="CLU_043419_1_0_1"/>
    <dbReference type="OMA" id="DKLITCC"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="447"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="57686" checksum="A992342010AA0836" modified="2013-05-29" version="1">MATTSTATAPNAHTQNHLDTKPGGSKAAPSAGARQDGGPPGPPPVGPVPPTPAKQINGASKSPAPASTHATATPGGGSTAQNTPGKGKKKPDPPDVMAMYESVKSRIAALESEEVHGEEEEKKITEEARNSIKDQTESAIQQKYIELFAEMKRLEREHAKERQKLTKDKDAAKSQLTKANQGRTKLENLARELQKDNRKLRDDGKRLAGSIEEVQEELAHMKTQVERRTAALMRRRDPSRLAPNGQAPSDLVVKVVCKYRAELFFKISRKTKLSRLFSAWTDRMASAEEATLSQQEKGKGPVVTSVDGKEAKGKKREPPPMTFLFTHVGRSLEPDTTPDEAGMEDGDEILAVELMDLTGPEVEKELPDGKRVLLQKNWTDSPAEARKAVEELFDGMVRERLKDVLRQYELREKHFDCVIRSKELEVLLAQARVDESRHAADGERRIATVAETQNQQLRLQMEEMQNSQARLMDKLITCCKEPTGERTQKLFAFLREELERRGTKVLDMMPPATPDLSGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Q3</accession>
    <name>M5G2Q3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoplasm protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_24590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624940.1">
        <property type="nucleotide sequence ID" value="XM_040773748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Q3"/>
    <dbReference type="STRING" id="1858805.M5G2Q3"/>
    <dbReference type="GeneID" id="63688810"/>
    <dbReference type="HOGENOM" id="CLU_002157_1_3_1"/>
    <dbReference type="OMA" id="HAMTVSV"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049517">
        <property type="entry name" value="ACX-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19278">
        <property type="entry name" value="Hydant_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="266"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Acetophenone carboxylase-like C-terminal" evidence="4">
        <location>
            <begin position="611"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="788" mass="86059" checksum="13224A71D61EF462" modified="2013-05-29" version="1">MGDSYTVPDRSIRICADRGGTFCDVHASYPDPQHPSTRKELVVKLLSVDSGYPDAPTEGIRRVLEHVEGRSIPRGQVLNTDKIDYIRLSTTVATNALLERKGQKHALVITHGFRDLLLIGTQARPKIFDLAIKRPSPLYTAVLEVDERVTLVGYTSDPESAENSVKFDREGKVVGGKMDDVGPGEEVVQGLSGEAVRILRRPDPSKILQDLRSLRSQGYTSLAVVLVHSYTFPAHELLVGQLAQEAGFEHVSLSSQLLPMIKLVPRGISCTADAYLTPILQSYLDGFFKGFDSKLRGHPHSSSPSASPSHSQSESESRSRPQDQDQLQLPAQGPRVEFMSSDGGLLDLENFNGLKSILSGPAGGVVGYALTSWDEEEKVSVIGIDVGGTSTDVSRFAGRYETVYETTTAGITIQSPQLDINTVAAGGGSCLFWRNGLFNAGPESAGAHPGPVCYRKGGMLAVTDANLFLGRLLPEYFPKIFGPGEDEPLDGAASARAFEALAQEIRRDTNRDMGLDEIVYGFVKVANETMCRPIRALTEARGFSTAKHILASFGGAGGQHAVEIARLLGMKKILIHKYSSILSAYGLALADRIYERQEPSSVTYSPSSLVQLRQRIDTLEADVRAELSRQGFAAENILTEPFLNMRFDGTDTALMVPAPADGSWDFERRFKEEYRQEFGFVLEDKGVVVDDLKVRGTGKTYTSLGPSVHQEMKTLRTRLVGEEKISMHTKVFFEQTGRVDTPVYELDKLEVGDQIKGPAMVIDNTQTIVLDSGSKATVTSGHLYIVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2T8</accession>
    <name>M5G2T8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631435.1">
        <property type="nucleotide sequence ID" value="XM_040767925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2T8"/>
    <dbReference type="GeneID" id="63682987"/>
    <dbReference type="HOGENOM" id="CLU_1539994_0_0_1"/>
    <dbReference type="OrthoDB" id="3355624at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="174" mass="18892" checksum="34604E92DBE3BA94" modified="2013-05-29" version="1">MAPKVMSVWQAALLVYLEPIGFSILGAIPVVMDPATFQAGHAPANQAPSSLTLANRVVLYQYAALLVVVGLSSTLVMHTALHLDDPTGRSQRRLIAAMQVALMLGDWLFASASIVPYFEAGLIDYLNPFKVFTGQTPYLMAPFLGVWLSAALTCMRIAWLSGVGQQRITEKKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G315</accession>
    <name>M5G315_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Brix-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_18227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625045.1">
        <property type="nucleotide sequence ID" value="XM_040771345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G315"/>
    <dbReference type="STRING" id="1858805.M5G315"/>
    <dbReference type="GeneID" id="63686407"/>
    <dbReference type="HOGENOM" id="CLU_026936_1_0_1"/>
    <dbReference type="OMA" id="KRTHAQI"/>
    <dbReference type="OrthoDB" id="10261452at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Brix" evidence="3">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="321" mass="35557" checksum="6E2FDEB0CBDCBAB0" modified="2013-05-29" version="1">MARRRKHRTHDKGAAPDADDASTPKSFIIKHGQVGSSLSGLVRDMRKVMEPNTASRLRERTRNKLKDYLTLAPALSVSHLLLFTLSERSPYLRIVRTPSGPTATFRIERYSTMADLRSGKRKPRGEGTEYRTSPLMVLSQFPQEPPNGLVAKLLQSLFPPLSPLSLKPSSARRVVLLSYDAETGTIQLRHYLISIRSYGVSRRVRKVLKPGLDLGNVKDVADWVLGEEGYESASSAGSEGEEMDLPVLAALGGRTRKGEGSVREGSTQGDRKRAVKLEEVGPRMELRLVKITEGVPGKEGGVIFHEFGTRSSVLFWSECLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G375</accession>
    <name>M5G375_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_83928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625085.1">
        <property type="nucleotide sequence ID" value="XM_040776651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G375"/>
    <dbReference type="STRING" id="1858805.M5G375"/>
    <dbReference type="GeneID" id="63691713"/>
    <dbReference type="HOGENOM" id="CLU_778498_0_0_1"/>
    <dbReference type="OrthoDB" id="3357985at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="64"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="356" mass="39096" checksum="D2089CF0CED20EDC" modified="2013-05-29" version="1">MARNAVAGVCATCDVHWAFMEGWKELQSMCMPGKITYFVPPSRTVSPTETNTSSIASTPAFDQGDVVLRSSDGVSLHAWRRILSESSPFFRALFDLPQQDTFPADSPECDSSLPVIDCQEDTSTLTSLLQLIYPLPNPTFLTIDELVPALEAAHKYDVPSAVSTLVTLLRSRKLLASDPVRVYALAQRYTLPSLSRAAASACLHTDLDDTSESSVLHLSASAFTRLLAWRNAHSQAIRKALTDTPFAYTCGVCRERWTARWLTLALYEVARRPVGEVIFSWEFILQAMDMERPASVGGHYVSGFGTGPTAATWGGVAVGSGHYCANAVTEGDREWMRALNMRVADLEEEMPEMMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3K3</accession>
    <name>M5G3K3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_57369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625235.1">
        <property type="nucleotide sequence ID" value="XM_040775435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3K3"/>
    <dbReference type="GeneID" id="63690497"/>
    <dbReference type="HOGENOM" id="CLU_008724_1_1_1"/>
    <dbReference type="OMA" id="MAHKCIP"/>
    <dbReference type="OrthoDB" id="79687at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14011">
        <property type="entry name" value="PK_SCY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="895" mass="97257" checksum="D82B6BB647556874" modified="2013-05-29" version="1">MAGIFAAATSLIRGTAISQNYTIGQPGASSTALPESTLTPTFNVGPWKVQAATHKVTAKQVSVWSFEKRSVDKMGAAGKERIVEVLKHEASSLSRLRHPCILEMVEPMEETRGEIIFATEPLTSSLALSIPVSRRSGGSGADSGELDEVEIQKGLLQVCRGLEFLHTSARLVHSNVCPEAILINSKGDWKLSGLGLTMPLSQPDGTPTRWEFPEYDNRLLLYAQRKFDYLAPEYAIDEQITVASDMYALGCVLYSVHNYGRPPFATHGSMNTLRENAARLGSGNAIQNAMMGGDLLDLVNHLVTRSPANRLTTATLPQQPFFSSLAISTLNFLERSTFSAKPKEEKATFMKGLLKVLPRFSEGLKRRKILPSLVEEMKDTWLLPFILPNVFEISKSLSKEQFAQIVLPNIKPLFQIRDPPQNMITLLDNLKLFQEKTTPAVFKEHVMPLIYAALESEHVNVQERALTAVPEVDETVDYSEVQSVLFPKIALLFTRTRVLSVKVNTLMCFLHLVKVLDTTTLTQKMVPLLARIRTKGVKIHRMATLDVHEAMGLKVDREAVATLVLPQLWSMSMGPLLSVDQFARFMKIIRSLGDRVEREQMQHLRENQRIEQQTSGGISGSQSVMAANGEMNFEDLVAGGSSPRPVAAMNGTSSTQPSTSSWDEVDPWDSIFAEAGAAVSSPKYSQRVTLISAQSTPASTTVSTFASPATTFPPLPQTSFTTSTNPRPAAQVSSPPLRSASLTSPPISQRTISSSSIPPLSSVNRYAPPVQRASSPLAASSWAPLQTQPISAHAQTPSGSFQTSKPNYNISMALEPPVSLGGSPFPMQPPSFPTTSLSFGLPVAPANPPSYGAAPIPFNIPPLAQSSTGILVPTKVGASTGDAKKTDWKDFDPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3N1</accession>
    <name>M5G3N1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625265.1">
        <property type="nucleotide sequence ID" value="XM_040773679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3N1"/>
    <dbReference type="GeneID" id="63688741"/>
    <dbReference type="HOGENOM" id="CLU_1610703_0_0_1"/>
    <dbReference type="OMA" id="AIPINGR"/>
    <dbReference type="OrthoDB" id="3349613at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="179" mass="18918" checksum="0EABD59563C53DDE" modified="2013-05-29" version="1">MASNLTQTLSFGVHEGAAFNDATTLGGFPNTQGIKSIKQIRLMAGWLIDGMEVTYQMNDGSTKADNHLGTGKPNVTINFNDDEVLVCVTGKTTLPGYYQNKPYLCYLKFVIVNTASGNIRVEGPFGNGAGDAKYTGKTFSVAGPILAFAGQSISGNEPANALTLSFLKSEQLALGKGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3V7</accession>
    <name>M5G3V7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Repressor of RNA polymerase III transcription MAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_93330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631825.1">
        <property type="nucleotide sequence ID" value="XM_040777146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3V7"/>
    <dbReference type="STRING" id="1858805.M5G3V7"/>
    <dbReference type="GeneID" id="63692208"/>
    <dbReference type="HOGENOM" id="CLU_037043_3_0_1"/>
    <dbReference type="OMA" id="NERFLGW"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037240">
        <property type="entry name" value="RNA_polIII_Trep_MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="36516" checksum="3FDD43E8C1F95963" modified="2013-05-29" version="1">MKFLEFPELFTLSNALTYDSPECAIRTRIEAYSCKSINREKKMFKALEHSYAEDIAFNLSVSPPEEALASPFGRLDQPSARKVLYLLIATLNVAFPDHDFSEVRPDAFKKEESPAGVLHSLSNTLLSLRPTPGSVSEYTPRSYSSYPPPLDVPSSPELSASYPPGSRKKTQDELLTGTHPTFYRILDNIITLKDCDVYSYTPGNEWDPHAVDSDDEDEISSDEDLDLDDWDAFDFELDTPADEGFATPTKPKPSKRLEETEIHYPRRRLGGLLWSANWFIHNKKQKRILFVSVWARKRIGGWMETRRTEWSAASARSLGLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3W4</accession>
    <name>M5G3W4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_30783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625350.1">
        <property type="nucleotide sequence ID" value="XM_040774341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3W4"/>
    <dbReference type="STRING" id="1858805.M5G3W4"/>
    <dbReference type="GeneID" id="63689403"/>
    <dbReference type="HOGENOM" id="CLU_045011_1_0_1"/>
    <dbReference type="OMA" id="TAPNGFW"/>
    <dbReference type="OrthoDB" id="1694274at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="257" mass="28622" checksum="F508608168E578BD" modified="2013-05-29" version="1" fragment="single">QYKAVVFDIGGVLLSSPVAVIRSYSSELGLPADYLNVFITNLGATSAWARFERAELSLWEFYDLWSQELSDAERGKVAYSQWLAKRGQPAEELKIRVYKVDGRELFGRMMREAAKFDPWILAAVQKLRALGKYKVLALTNNYTAAYDSLLAESASSPGAAVELRFLGWTSGPAPESMRALFDDFVDSSFSGCRKPEEGIYDLLLERNGLKGEECVYLDDIGENLIAGKGKGMRTIRVVVGKTREAVEELERVLGVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3X3</accession>
    <name>M5G3X3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629804.1">
        <property type="nucleotide sequence ID" value="XM_040775010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3X3"/>
    <dbReference type="GeneID" id="63690072"/>
    <dbReference type="HOGENOM" id="CLU_1975745_0_0_1"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="127" mass="14381" checksum="12268E7AEF021C55" modified="2013-05-29" version="1" fragment="single">FRTDDSSDSTNGRSWCALEYQDNWKGAAIPYAVMNQSYDSDLALEKAMYCGLELEVHNPANDRVVTVWVVDAFDQSWVHTNASLDLTVSAFQELNGTFNGDKDAVIKNMTWVFTGWLVLTWVVSTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G432</accession>
    <name>M5G432_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629864.1">
        <property type="nucleotide sequence ID" value="XM_040768208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G432"/>
    <dbReference type="GeneID" id="63683270"/>
    <dbReference type="HOGENOM" id="CLU_565012_0_0_1"/>
    <dbReference type="OrthoDB" id="3041441at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53665" checksum="067BB72A537FA8ED" modified="2013-05-29" version="1">MPRPQRPHRVWIVEDVICDVMSYCAPRDICNLGMTCHCLFQIYLDVVFGELDSLGPLYGVLPDPSLSPAAPTGLRSLISRSHASKKAHNPKTHSVGRITMYTARVRSLTIGQGGEDDAHRINNLRSILGPLPLQTCFPQLQSLRIIADDPRTVANSIPLALPMLRSFALIINFEDRKLDLSVKDSYESSGLPVYFRHLRSLSRLDSLTITCANTSRRPVSEVEAHGLLYLTRQFPRLSTLDISNLILTDTLVHNLSKLPMLERLFVCLPNGKESVLTPGPLAFSNLHHLTINCDATELSWFMHGLQAPHLASLQLHAGCRALCPQTAPKFSELVGAKFRNLRVFGLHVWSEDGSDTCWTFASFHGMLRCRAMECFGVMLPSLVIATDEDVQLIVKAWPRLRDLQLGHSQVTSDFERPSPGSTSLFIQGPGCVAFTNAKLPLTVAGVMLARPSNDETILNFHRRNCSCYPSFIPSNPVIHLHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G490</accession>
    <name>M5G490_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625465.1">
        <property type="nucleotide sequence ID" value="XM_040773591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G490"/>
    <dbReference type="STRING" id="1858805.M5G490"/>
    <dbReference type="GeneID" id="63688653"/>
    <dbReference type="HOGENOM" id="CLU_460803_0_0_1"/>
    <dbReference type="OMA" id="ALWERYS"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="592" mass="66642" checksum="1E3F409978007AF7" modified="2013-05-29" version="1">MESYDKLALDVFKQLVGEGYIPESAMMQQVEKVPTEAEGAPSISDAEHFTFVVIGTLVKMCLHYGYDQLAHDFMQSLQSTAMFDPVYRAAASKVIGTLLLSGTEKDAELLAGLVTSWAADVASVQPLRDDIIWLLYDFCHHVLRPDLIAFIHGRLSTPVLVDVYPVPQNHALVALLTELNHRNNIIQARNLIRTIFRNNYRVDPFHRANVIYQASQMGFATEARALYERYEHRAHSERVTGSAMLATELVAHFVRISEDQSQKLDKRAQDDARAFAQRVTSNLVASRAEMAKIPRTALNAIAHCHFLLGDLEAGFRTLRVILRRREVPHDNDVNVLLTAAAKYSPRAAVTLLKKALDDNYRASARAYAVLLHYARKSGDDELAEEVLRLAEDRGKMAHLDTTVKNSMIRTQLLPLISGVIQPPDTVRQALQTSFETMTWMKNQHRKVNDSLVHLAIRAAVANYRLSVAFAFWNDFFRGRVFEENDPWFSWEERLLVRIERAVQSGKLPRDKGFAMLNQLKENGITQGWVTDEEGLKREIMPFALPPLPAQEPDVGVQSGDEARSQQLPDHSADPVIPGDVADVDTMNDSLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G559</accession>
    <name>M5G559_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22811</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627869.1">
        <property type="nucleotide sequence ID" value="XM_040772960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G559"/>
    <dbReference type="STRING" id="1858805.M5G559"/>
    <dbReference type="GeneID" id="63688022"/>
    <dbReference type="HOGENOM" id="CLU_073661_0_3_1"/>
    <dbReference type="OMA" id="RMDLGMT"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidyl-tRNA hydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Bit1"/>
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    </dbReference>
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        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRK04322.1"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
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    </dbReference>
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        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
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    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="20670" checksum="B430D964E9C89231" modified="2013-05-29" version="1" fragment="single">MSFASGGSWNPVAAYASVAVAAGTVGYLLGSRQRLSQVKIDHSSKSQCDVLEDENESASVSDDDIGDEDLAAVKPGIMEECKLVLVVRSDLGMTKGKIAAQCSHATLACYKALSKSNAQLLRHWEKTGQAKIALRCDSEEELLLLQAQAQSLSLCARTIQDAGRTQIASGSRTVLGIGPAPVRLVNQVTGRLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5A7</accession>
    <name>M5G5A7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_67774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775858.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G5A7"/>
    <dbReference type="GeneID" id="63690920"/>
    <dbReference type="HOGENOM" id="CLU_061221_2_1_1"/>
    <dbReference type="OMA" id="DLIFNWQ"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
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    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="85"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="216" mass="23332" checksum="668A484B93142F28" modified="2013-05-29" version="1">MIHAVLIFNNTGLPRLTKYFVPPSQRAHISPKAIFSLVSQRAPQLCNFLDVPHQSPLRRTSSGLGTATGDEKSGWENGRTPVEVDRVIYRNYATLYFVFVVDEGESELGILDLIQVFVESLDRSFENVCELDLVFHFDEAHAILSEIVQGGVVLETNVDAIHEATQAAAQARRSSFAAANPLALGSGSGVSSRGAGEGLVTPLGWVTGKLLGGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5C0</accession>
    <name>M5G5C0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632345.1">
        <property type="nucleotide sequence ID" value="XM_040767847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5C0"/>
    <dbReference type="STRING" id="1858805.M5G5C0"/>
    <dbReference type="GeneID" id="63682909"/>
    <dbReference type="HOGENOM" id="CLU_1740467_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="150" mass="17270" checksum="C9E20911FA343C4F" modified="2013-05-29" version="1">MDDINPTEPLDRGYLLCFWKYAAPKAYGAFAFCECWLAEEAEKRLNSTEEETHSYWATGAELEETHIYQRIAQAYWRSGAALKTTLPLMKILNLGLPQAKKIGEHSVFGLQRGFDSFEDTLRYLADVEKVLAERYPRFDSRALVDEECAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5N5</accession>
    <name>M5G5N5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_806587_0_0_1"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="344" mass="37981" checksum="55DB781F1063A578" modified="2013-05-29" version="1">MAPSKSRKRPLPIDNNDKEMVQQPPPRRACINSGNLGSAGNAGNAGNPSLSPNPNAYFPNNDMAKEVAFLDTLYGPSGNYAPHHSSHLSTVSNALSTAGSAPPSCTGSSNAGNAGMAICSPPAQSTSQWEKELSKPPPGYEEDETFRARQEEADAEMAREMQDFLDGGGVLEEDMVKPPPVQAPTMPAWDKEKDFFDVLLEVETYSPAELQAIYKLKHPNPYIPAKAMHNAQPESRVAPTYSKPTMLPTFTFDFQQYMHGIECNSPIHFGPYQLVMCKKPDDYSDEVKHIRNAPIDTAALLEDGLDVPGINCYPLAEAFCHHNRRWIFWNVYLHDLFCMPQPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5S6</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_22917</name>
    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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            <taxon>Dacrymycetaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5S6"/>
    <dbReference type="GeneID" id="63688077"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="51" mass="5697" checksum="3F58569E4969ADDD" modified="2013-05-29" version="1">MNDPSGPPQSHDPLEESSSILLDSPRTRLQLVAFQIQDLNVQCRSQSLGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G608</accession>
    <name>M5G608_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">DACRYDRAFT_22468</name>
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    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63687877"/>
    <dbReference type="HOGENOM" id="CLU_2454698_0_0_1"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="89" mass="9817" checksum="C9A6150B5A7E74A3" modified="2013-05-29" version="1">MPEDLQPRAKAQFLELGCRVLTGGRLSRDAAAYEWRGGCLTGEGRSASVQYGKPHEGSYRTYSVSQDPRSSKRSNRPTDPYASSPVYTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6J0</accession>
    <name>M5G6J0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S17e</fullName>
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    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_22578</name>
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    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040772865.1"/>
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    <dbReference type="STRING" id="1858805.M5G6J0"/>
    <dbReference type="GeneID" id="63687927"/>
    <dbReference type="HOGENOM" id="CLU_112958_0_1_1"/>
    <dbReference type="OMA" id="HTEHIEV"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU01437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="146" mass="16514" checksum="790A7CD5A82B5137" modified="2013-05-29" version="1">MGRVRTKTVKRASRILIEKYYPRLTLDFHTNKRLAGEVAVIPSKRLRNKIAGFTTHLMKRIQRGPVRGISFKLQEEERERKDNYVPEVSALDVGEAGLEVDAETQALLVALNSDIKTTLLQPVTAFVAPERPRRERRTVPGAAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6R2</accession>
    <name>M5G6R2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630789.1">
        <property type="nucleotide sequence ID" value="XM_040772330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6R2"/>
    <dbReference type="STRING" id="1858805.M5G6R2"/>
    <dbReference type="GeneID" id="63687392"/>
    <dbReference type="HOGENOM" id="CLU_018327_1_0_1"/>
    <dbReference type="OMA" id="EAWQNST"/>
    <dbReference type="OrthoDB" id="79367at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="696" mass="74580" checksum="3C534368FADF8260" modified="2013-05-29" version="1">MADLQEFEKVLKDVVNAKRLSASRINTLTELCLKLIENDVQLVSLLYRTHKSLPSSQKVFSLYAFDALARAARHAVVKNKITVDPMGTKGNCATFLNKVEGVLDSLISDMLSSGGKEQREKTKKIVDIWTSNNTFSKEVLIGLSAKVKAAEDKATARASIVPQSTTPPGAPVANAAQAAGVQQALLALLSQAAAAKSSTPPATTSAVVPPPAAPTPGLVIDAQRLLQQLAGQVQNQTQLVMPTVPAVMPSAVPAAPSPPPKPLPIYAPNLPPPPDQMAAQRALAVPQMSLTTDNSRFDSRPGGSRPPQWGDARERSPPPRDERDNGRRDDYGEDNRGRGRGRGRGSDRNGWDRRGGRGRDRSPPYGGRERSRSPPYRGPVNNRFDDRRPPPVNDGRIPRRDSPVRNRSPPHYRSPPPRDTGLMAQSMARKDEFGRDTRPGDDRTLNNASEGAQLPRSEFNPVGSKITSTSSPPSSSSVAPIPTVLDVPNRIGLDKFDWSTFNFGSPESWDALGKAFQVTNGHLPSQEEVMTIVMQSQMGGMMGNMMGMQTGGATGPGNDEFSNTATNGQSWQNGDNEGYRGGGRGGRGRGRGRGGRGGYGYGRGGGSGDNAEYGGYQGHQASFDSNYGGGWGNGAQKWNNGDQAWAGDDESNGYVIQPSAPVTVSNQTDEDTSPLMKKQGGQMVKIGDRWQWVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7P4</accession>
    <name>M5G7P4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626695.1">
        <property type="nucleotide sequence ID" value="XM_040768841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7P4"/>
    <dbReference type="STRING" id="1858805.M5G7P4"/>
    <dbReference type="GeneID" id="63683903"/>
    <dbReference type="HOGENOM" id="CLU_743988_0_0_1"/>
    <dbReference type="OrthoDB" id="10542849at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="372" mass="38866" checksum="857CF4F283F0D7D5" modified="2013-05-29" version="1">MDASTVVVGATDPGMSFLPQGTWNLTNADTVTLMQGGYPSQILYSFPSNASGFQWSGCKSGSGDAALLCFDCDCSSGSPGPSATVLSVNFSDFSLGNSLLPPTVLYETQLEWGRHNVCISNAFERMEQVAGQEEGVWGWIFHYEFRVNVTDPGAGTGTSTATTSTTSTVTGTPTNTLPPASAPATPDPTPSPAPTGAITGGVIGGLAFLLVASLTMIYYFGHYCNIHLPFLPAYRGPVRRARLALDDESPPGTPPTGSGWSASTPGSERQILPLNAVPGRGLQSHSRMLSDEGRSPSLSPAISQAASPRRPYPHSPSPSRSSIAQTEGGAPSSEESETGRASGSSDIRSRVTTEPPSYDEVLGMEPARTGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G825</accession>
    <name>M5G825_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626810.1">
        <property type="nucleotide sequence ID" value="XM_040768865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G825"/>
    <dbReference type="GeneID" id="63683927"/>
    <dbReference type="HOGENOM" id="CLU_1503388_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="179" mass="19159" checksum="8E9F632F988A47A0" modified="2013-05-29" version="1">MDIGSENTLFANNEGPSDRYSRSLSNLINSIASASFLTIPLPASPKHPQLVSPVSASPAINNVPLINIPIPAAPSPVQSAPQELPVLEIQSVLQLLSVPQVEPAPQVQLVTEPQPMPELHLTPEIEPALEVQPTPQVQPPAETQPVTTTQPSREPSVETGTTPPDIQPNLPTWLRNILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T6</accession>
    <name>M5G8T6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Superoxide dismutase</fullName>
            <ecNumber evidence="9">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_81089</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="9"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627075.1">
        <property type="nucleotide sequence ID" value="XM_040776491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T6"/>
    <dbReference type="STRING" id="1858805.M5G8T6"/>
    <dbReference type="GeneID" id="63691553"/>
    <dbReference type="HOGENOM" id="CLU_031625_2_0_1"/>
    <dbReference type="OMA" id="DHHGNVG"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000002">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="10">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="11">
        <location>
            <begin position="116"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="219" mass="24234" checksum="C19053459D6A6354" modified="2013-05-29" version="1">MLPIVRPIVRALTRPATRAFAGMRLEHTLPPLPYAYDALEPYISKEIMTLHHDGHHQAYVTGLNAAESSYAATDDIRERIRLQSALKFNGGGHINHSLFWPGLCPASSSSAKLAPGPLKEAIEREFGSLEALQKEMNAKTAALQGSGWGWLGVNTSTKKLEIVTTANQDPLLTHVPIIGIDIWEHAFYLDYKNVKAKYLAAIWNVINFEEAAKRHEAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T8</accession>
    <name>M5G8T8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">XAP5-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_92589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632043.1">
        <property type="nucleotide sequence ID" value="XM_040777090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T8"/>
    <dbReference type="STRING" id="1858805.M5G8T8"/>
    <dbReference type="GeneID" id="63692152"/>
    <dbReference type="HOGENOM" id="CLU_037985_1_0_1"/>
    <dbReference type="OMA" id="DFIWVFL"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="207"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="39863" checksum="DF1111E6A3F17D31" modified="2013-05-29" version="1">MASNSGEPWCQGALEKKRQEMLAEFERQKDLIRQETEKARPGQNRFVGVQDSTEDALKKSTVGLVQLEEFQSARRALEELKAREAARTDELGKEVKKVKKKRKAVKNNLSFAMDDEEESAGPSGRSTPQPKAVSRELTSAPTPNTDANDVATPEGDEERPSKRPKLGKAPGVDTSFLPDREREEAERAERESLRQEWLQRQEDMKQEEIEVVYSYWDGQGHRKSVICKKGDEIGKFLEKVRQQWSELRGVTTDNLMYIKEDLIIPHHYTFYDFIINKARGKSGPLFNFDVHDDVRLLADATVEKDESHAGKVVQRSWYNRQKHIFPASRWEVYDPEKDYGKYTIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8U5</accession>
    <name>M5G8U5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_116012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629179.1">
        <property type="nucleotide sequence ID" value="XM_040770115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8U5"/>
    <dbReference type="GeneID" id="63685177"/>
    <dbReference type="HOGENOM" id="CLU_1294365_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="213" mass="24127" checksum="27A8C71C56C74EF0" modified="2013-05-29" version="1">MDFGILTFVHNSAPRRGDPRANQENPLSASCLETTNAQWDTTAQISASDSPAPPANEQLMDRLAQIQQTLIDGLARVDQRFDGIEGTLTGIEGTLTRIEGRVTHIEDTLTRELPVPRDGLRRVECMTAKTWNGRCNKKGVPRYARVPRDDHVAYNEIPDIQDFNRLRDADNVQVNQWLRFYGRSRHGTLAKKKFRLGRYIGLDRLQCNILLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Z1</accession>
    <name>M5G9Z1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629596.1">
        <property type="nucleotide sequence ID" value="XM_040772510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Z1"/>
    <dbReference type="STRING" id="1858805.M5G9Z1"/>
    <dbReference type="GeneID" id="63687572"/>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OMA" id="CACHKDY"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="313" mass="35099" checksum="CFA64F5CAFBF7C79" modified="2013-05-29" version="1">MSVPVPTYNGIPAVGLGCWMGQPGASEEAYHMVREALKIGYRHIDTAFGYENEEAVGRAIRDSGVLRSEIFVTTKLPNQAHHRVVEGFENSFKNLDIGYIDLYLMHWPCAADDSGRQLSPKEGRDFVEVWEDMENLLETHAGKVKRIGVSNFSITLLEVLLPQVKVVPAVNQVEVNPYHPQIPLKKYCESKGIQIVAYGPLGQTRRTFLEDHEVVAVANKYGISPAQVCLSWAVQRKTIPIPKSSNPERLKQNITLVTLAEEDFDRIENLHKEPGKHRSSDGMTLKVPGSVWGWTMQEMGWHVNLDGTIAEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA18</accession>
    <name>M5GA18_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629661.1">
        <property type="nucleotide sequence ID" value="XM_040772526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA18"/>
    <dbReference type="STRING" id="1858805.M5GA18"/>
    <dbReference type="GeneID" id="63687588"/>
    <dbReference type="HOGENOM" id="CLU_023205_1_1_1"/>
    <dbReference type="OMA" id="WNDAYFN"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="38081" checksum="830F30BC9A3246D6" modified="2013-05-29" version="1">MPEQKSELNIVMGAMTFGEEGKEQARVHDLKDVEAILDVFQAHGHTEIDTARGYCGGTSEEYLGKIGWQQRGLVMMTKLYPTGARNRLGSADAITHSAEGVRKGLEASLKALQADKIDTFYLHGPDRGVPYEETLKAVNDLHKEGKFKRFGISNYMSWEVAEMVLICRANGWIQPTLYQGIYNAIHRAVEPELFPCMRKFGISFYEFNPLGGGFFTGTYSSKDQFVEAGSRFDPTKNQGQSYRKRYWNDTYFQALELVKAVADKHQLTMAEVALRWVSHHSLMKREFGDSILIGASSLKHIEQNLIDLEKGPLPEEVCKVLDEVWDLVKAVAAPYYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAE3</accession>
    <name>M5GAE3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_78824</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629811.1">
        <property type="nucleotide sequence ID" value="XM_040776363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAE3"/>
    <dbReference type="STRING" id="1858805.M5GAE3"/>
    <dbReference type="GeneID" id="63691425"/>
    <dbReference type="HOGENOM" id="CLU_030284_2_1_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU02917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28998" checksum="901A9B967F0CD58C" modified="2013-05-29" version="1">MGRTYSEWWMHGHQDLPPNFGDYLELHVGNKFMVQMACDKGATDYYASSDGGDIRDGNWPCPNASSDEWHTRDINDTKGCGFGIAYKSDVSTVGPEDITIFSVNYTCPWYRYQWFDVPADLPPCDDCICTFNWIHSPDDGSMQMYQNGYKCKVINSMPGKQLQIPQLARRCGDDPDFNKPPDPTNCTGGLKGGAKQGLYWLQQDGNNMFEGYYAPPYYNALYDFSNGAQTDIFISNGVPTGNSVSSTLSADSSVTTSTSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAZ0</accession>
    <name>M5GAZ0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_45083</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632968.1">
        <property type="nucleotide sequence ID" value="XM_040774623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAZ0"/>
    <dbReference type="STRING" id="1858805.M5GAZ0"/>
    <dbReference type="GeneID" id="63689685"/>
    <dbReference type="HOGENOM" id="CLU_012062_4_2_1"/>
    <dbReference type="OMA" id="FADEWEG"/>
    <dbReference type="OrthoDB" id="3341165at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="164" mass="18054" checksum="B4E24A97EB42BD78" modified="2013-05-29" version="1">MDVEIGGEPAGRIIIRLFSKDLPITCRNFMELARGVHGFGYKGTKFHRCIPNFMIQGGDFTTGDGTGGRSIYGPRFRDENFKYKHTKKGLIAMANTGPNSNASQFYICCQKTSHLDNRNVVFGEIAEGMDVVHKVEKCGSAPGDVSPDCLIVDCGSIDWTPTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBF8</accession>
    <name>M5GBF8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Large ribosomal subunit protein bL28m</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628235.1">
        <property type="nucleotide sequence ID" value="XM_040772838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBF8"/>
    <dbReference type="STRING" id="1858805.M5GBF8"/>
    <dbReference type="GeneID" id="63687900"/>
    <dbReference type="HOGENOM" id="CLU_064548_4_1_1"/>
    <dbReference type="OMA" id="LWCEALG"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.40:FF:000003">
        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_bL28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_bL28_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="129" mass="14843" checksum="0A0F60BD831AFC0B" modified="2013-05-29" version="1">MFRTLARLYNIQALRGPTTHLFEGRTTLSGYNVPHSKHKTKRKWKPNVHTKRLFSESLGGTVKVRLTASTLRTIDKYGGLDSYMLRNKNLHEFERMGGSAMALRIRIREAEKEKVDKALAEEMHKMGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBJ2</accession>
    <name>M5GBJ2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630321.1">
        <property type="nucleotide sequence ID" value="XM_040768114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBJ2"/>
    <dbReference type="GeneID" id="63683176"/>
    <dbReference type="HOGENOM" id="CLU_741902_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="42035" checksum="02644A5F0C41D38E" modified="2013-05-29" version="1">MFQCATSKPEPFFIAQKFCNRSWERFQLYSFHIRTLLLTRDLVKQASQTTTLACFGAIMDYEQRNLTIAFPSLRQLAFDVKGDRMLKILPDLLSEKLQILDISFFSYHDRSQQVKFFPSLDQLLEFPSILGAKCPNITELVVRNMPDEFPKQARLLKGLMLATPKVKALHLLPPWSSSGLYPGVFTTSSAVHVGLEALSVVFCDNSSEAIAQLRAQPRASFPCLRSLCIRSLGRTAVVTALSACAMSPLQNLRVEIGEYSYSHRPYNRGSFDMKNDVDGSFQSRLLEVTTAICSLSSIHLDELSLEVHHPRLGATARISKLSNVVSFGDNMKPLLQHFHHISKFCLTLHFRATFAEGLLLDIRDEDFSLVPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBU6</accession>
    <name>M5GBU6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UBC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_38569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="GeneID" id="63689506"/>
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        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBV7</accession>
    <name>M5GBV7_DACPD</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19300</name>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="421" mass="47350" checksum="C6E6F8369AC45A8B" modified="2013-05-29" version="1">MAPATAEAIAARAKEHQDILDELATLEYAPAALRDNEAAIKSLTERIDASSQQIIVLHKKTNREHKDFAKLQNSAGRRLWVKIKHGGKKDAVEKKLEKEEREFLEALEQEQAAEEVRAAMQTEKDSLASKNPELQQKAGRHKQLKTKLELLYRSLFEGFTPDYPYEDEAEERVRQAEDANTNFQTIVNRESQVMTLLTSAKTCLNNTTDLLHTAQGWNYNNMFGGGLFADMFENNALIDAKAYACRAQALVQEAKKKQPMVADINDVDVAQLDFLVNIVFDNVFTDIMFAERIQTSLATVHYGLQRVQNDLNQSNQRLTVANSNMRQAASTLTQRRKELDEIRRTILQSLLNHQPLPVIYTEGQPVGGGEQLPAYERVEGGKPQSIHLLPVHLQALALAPLPGRRLPSPKAGRYRQTLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBZ8</accession>
    <name>M5GBZ8_DACPD</name>
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        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_92181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
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                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
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    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
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            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040777049.1"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_009161_2_1_1"/>
    <dbReference type="OMA" id="AMYKTYK"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21638">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="65"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="199"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="544"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 C-terminal" evidence="10">
        <location>
            <begin position="683"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="516"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="623"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="725" mass="81963" checksum="05FBCA26A5138C3F" modified="2013-05-29" version="1">MTRAHSSRGPLLTSNLPQLQNLIKRDPAGYKEEFLQQWNHYQSVMLIFEHRPAEHAEQFRELVTFIAQVSQCYPVETATFSSQIASLLLRSFSTLAPDTRKSLVQNLVLLRNKGVINSIELLQTLFPLLSQTTSTSLRSFIRRTILLDIRTANQKAQNHKLNRSVQAMLFGMLERGMGAEMIGDKGKLRERLNEAPRRSTDEAVWAIALTKELWKRGVWKDEKTVSIVALGCIHPSAKVQKAAYYFFLGSEDDDEPCSEEEDEGPDIKQLKHQRLVKKKTRSEDRKIAKAVKIAKKKTKTNDDAKGNTNFWAIQLIRDPQTFAEKLCDHLQRYDKRMSLDHKVLIMQLLSRVMGYHKLCVLGFYGYVVKYLTYHQLRVTVILVALAQSVHDLTPPDVLTPVIRKLAHEFIHPGVGSEVIAAGLNAIREVCRRQPWSMEEDLLGDLVEYRKSRDKGVMVAARGLLQLYREVNPGLLKRRERGKTASMANSSVTPLPYGHAPKPAVDIEGIQLLQEQNHSVSDDRGEDNWEGWEVESDSDESSSDWIAVSSEDEGDIVISDSEDDGDRSTRPPAPKEYSATPHPVESIATTKILTPADFALLKKLKSESSPHTSEGNRGTKRKANSTSAAIESEQATFVTEADIMGPRKRVKADYEERMASVREGREGREKYGSKKGKKSKDVPSSTTNRQKARNKPVMMILSSNAVRSKKRASLREKQQRLRKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC91</accession>
    <name>M5GC91_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_60685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633009.1">
        <property type="nucleotide sequence ID" value="XM_040775643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC91"/>
    <dbReference type="STRING" id="1858805.M5GC91"/>
    <dbReference type="GeneID" id="63690705"/>
    <dbReference type="HOGENOM" id="CLU_045495_3_1_1"/>
    <dbReference type="OMA" id="PMEQFIK"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="31"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="292" mass="34342" checksum="A5E1196ADDDC5C8C" modified="2013-05-29" version="1">MNVVKEIQKINEHELQLGTRGSWHDQYKDSAYIFIGGLPYELTEGDVISIFSQYGEPVNVNMPRDKVTGKPKGFAFLMYEDQQSTVLAVDNLNGANIVGRTIRVDHVSKYKNLERGEDGKMKEAEEEQFNAMPQMIEDGGDESEESVSDAPSIDPEDPMRDWLLQRRKEEKAATKTEKKKKRKREHELPEERVARKERKRLKKLGIKADQNVKSISMTDRLTAREPDDHDRKRRHYGEDRKWEDSGRGATYREDRNDRPRDRDTYDDRERRSDRSPRRSPTQRGRSYRDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDB1</accession>
    <name>M5GDB1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_115963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629115.1">
        <property type="nucleotide sequence ID" value="XM_040770103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDB1"/>
    <dbReference type="GeneID" id="63685165"/>
    <dbReference type="HOGENOM" id="CLU_1981538_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="126" mass="14633" checksum="364EC2883A6B6889" modified="2013-05-29" version="1">MDALIRLGTTLRSNSLPLKKVYRNAQHDWVDFIDHRSGDWEWNAAKRGDVNCVMPKLVKLRDFIQVWLDEWMKKPTIETSVLTFLPCCLCLAGIQTRFAVTVGHPDNIQLLTKAKLFDWYASRLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDG4</accession>
    <name>M5GDG4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_21024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631406.1">
        <property type="nucleotide sequence ID" value="XM_040772192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDG4"/>
    <dbReference type="GeneID" id="63687254"/>
    <dbReference type="HOGENOM" id="CLU_799312_0_0_1"/>
    <dbReference type="OMA" id="RVVILWD"/>
    <dbReference type="OrthoDB" id="3354157at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="347" mass="38815" checksum="191F982818194ABB" modified="2013-05-29" version="1">MSVALVLDATDVANAFATSYIEAAAMTALIYDHLLTLAEEIELIWKSSFSLVKILFLINRYSVLGVMLVQTWSMAGYATGLNDHVCRNLFFAVSTWQLIAGGGISPFLLFLRVWSIYGRTRTVQVVVGGLCAANFIAILISATLNIWILLGNIYYAPQINRCVCTQRPEYVWVIWVTPLIYETVIFGMIAYKTWTHMREDIQTPIITALWQDGILYFTVLVAVRLYTILAWIVAPPSLFFMGIYLMLATITTMASRTILHLRAAARQRDSGYITPSWVAEESGLPPMSEWLGLRVITWTDGINVVDGDAVARGAMSIQAGNLVHSRSTSTLRRDVVSVRRETEVVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDJ9</accession>
    <name>M5GDJ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_75451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631481.1">
        <property type="nucleotide sequence ID" value="XM_040776137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDJ9"/>
    <dbReference type="STRING" id="1858805.M5GDJ9"/>
    <dbReference type="GeneID" id="63691199"/>
    <dbReference type="HOGENOM" id="CLU_054794_1_0_1"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="OrthoDB" id="539398at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="253" mass="28095" checksum="A5AFF16648AC8FCA" modified="2013-05-29" version="1">MPTYYPSIPEELGEWAMRQPLFWVASAPRAGQHINLSPKGYATFAVLGPNLAAYLDHTGSGAETAAHLYENGRITLGWCSFEKGPRIMRIWCKGRVVEVQTKEFDDLMRKIKAVQKRLGVDLGYGEQADGVRAIVVLEVFRCGTSCGYGVPLFDGTFSERPTMDDFVTKLVAKNGLTKYRTEWNVRSHDGLTGLRQARREGGKWLPLGEMVAWMRMMWGLRDAVLLGIVLGVLGMVLLGKVQAMGGLRALMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDX0</accession>
    <name>M5GDX0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629657.1">
        <property type="nucleotide sequence ID" value="XM_040772524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDX0"/>
    <dbReference type="GeneID" id="63687586"/>
    <dbReference type="HOGENOM" id="CLU_1845017_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="139" mass="15781" checksum="84772CC6C32FCF7B" modified="2013-05-29" version="1">MTRENLPVLGVSDERNFVFNHSWGKEMLWNDLVSPHQAHIACWLFGRHHDTELEQDTERFPTPVEFGDTALQLDCRSQGAGKHSSRSSKCGSFDVRKTQQISLVCSDDHPTLHHRAPCRVLPGKRDEPCSQYRLAAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE32</accession>
    <name>M5GE32_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_65062</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629827.1">
        <property type="nucleotide sequence ID" value="XM_040775771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE32"/>
    <dbReference type="STRING" id="1858805.M5GE32"/>
    <dbReference type="GeneID" id="63690833"/>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_1"/>
    <dbReference type="OMA" id="WAEVPDP"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="11"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="337" mass="36274" checksum="4CA02BFF290C8C7C" modified="2013-05-29" version="1">MRAVLIKGGIGSADDLYIGNYENPTPSKGEILVKIVAAGVNRLDIMQRSRGPPALPSASKDILGVEFSGRVEGLGEGVSDFQIGDEVLGLAPGAAYAEYITVRSGTVMKKPADLGFVEAASIPEVWFTAFQAIVLIAHVTANDTVLVHAGASGVGLAAIQLARFLGVKTVYATAGSDEKANFLSSIKNGASHAVNYKKQDFAVEIDKATNGKGVDVIVDFVGQDYFSRNINLLRTDGRLVLLATLSGKEIPNVDLGPILYKRIHIGGSTLRTRSLEYQAKLTSRFVDEVLPYIKGETVEESPLKTYLYTVYPWQDVAEAHKDMEANKNTGKIMLRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE44</accession>
    <name>M5GE44_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_106141</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU02963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629857.1">
        <property type="nucleotide sequence ID" value="XM_040768205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE44"/>
    <dbReference type="GeneID" id="63683267"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_3_1"/>
    <dbReference type="OMA" id="ITECYSG"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF64">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006528054" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU02963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="519" mass="56102" checksum="73AF448E9757A155" modified="2013-05-29" version="1">MASTRCRWLWVLALLLHTTYARHLPVIDGVIAGVAGLVPRSPTVWTPLPVVSLLASLKLGIVIRSPPTDPGTFGTVGTLRYVENSGVCETTPGVYQASGYADIAQNQSIFFWYFASRKGEEGAPLTVWMNGGPGSSSMLGLFQELGPCRVTDDALNYAYNPYSWSNASNMLFIDQPVGVGFSYGTAKVNNSQAAAEDLWTFIQVFLSDARFSRLANSSLGIWTESYGGHYGPTFANYILQQNTAIDTGLVHGIKLNLSTLGIGNGLTNALVQYPHYVTYAMSNPYNVMLANDTVLTNANTSLYTPGGCLDMIEDCYASQTRNGMANASVCAEAQQFCNKFVLTPIVGNYDEYDVRLQQPALYPPDILHLLRDPALLSAIGVPSYVNWTQSSKQVYNNFARAGDWMTNTAPYLENVINAGIRVTLYDGDADYICNYQGFQAVADALNTRYTSAWTAEEFNSWKVGGQAAGVYKNAGPLSFVGVAGAGHEVPAYGTATFAKGQAALALFEQTLQGLPITST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEH2</accession>
    <name>M5GEH2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF862-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_78156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630142.1">
        <property type="nucleotide sequence ID" value="XM_040776316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEH2"/>
    <dbReference type="STRING" id="1858805.M5GEH2"/>
    <dbReference type="GeneID" id="63691378"/>
    <dbReference type="HOGENOM" id="CLU_033441_0_0_1"/>
    <dbReference type="OMA" id="VTLQMAC"/>
    <dbReference type="OrthoDB" id="21221at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="7">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="174"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="6">
        <location>
            <begin position="316"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="611" mass="66048" checksum="37E1328D35FE05A2" modified="2013-05-29" version="1">MSKVELYVYDLSSGMARSLSLQLTGRQIDGIWHTSVVVFGKEVFYGQGISVVSPGTSHHGRPLQILDMGLTHLDEGTFQEYIDELSSHYTADKYHLLEFNCNSFTNDVVGFLTGGSIPGFIKDLPADFLNTPLGAALRPTIDSMFRGPPTAPPTPGPSLPSGTSPSPSSSPLASLVSRPPPVPETATLTAPLQLATNPSSLRSLLNSHKAATVLFTAPATCAPCRVIDPFFSELAQLRTAEGLAYVKVDLDVGLGRAAAQEWGVSATPTVMCFLKGKKRGEVRGANVREIRTQVDLLICELYPPHPHTRQDLPAIQGISLSPILFSQIPKLDSALSKFLSFVNAASASEGDKKRYQFLFRQVLLLLEPQAKLPPAQLRSTLQAWSAATVDLAALLPEGELFPLADFWRLAVLSSPVAHALSGNIEGIKSLLSLAYYSGASTPRPYLLTTLRLCANLFAYPDLARLVFPSEGEKQDLVSFLVCTLLSDDAGIRTATASVTFNLGALHQQAVRQALEKHTRPPSEDWIIEVVSALIEALSRETSSEEVVHRLVASLALFVFRAPGWEELRELLQVLQAQEVLLDKLLPGGCGEIGVRQKSVQVLVKELAGLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEW1</accession>
    <name>M5GEW1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_20129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632631.1">
        <property type="nucleotide sequence ID" value="XM_040771807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEW1"/>
    <dbReference type="GeneID" id="63686869"/>
    <dbReference type="HOGENOM" id="CLU_000960_27_0_1"/>
    <dbReference type="OMA" id="VWTLYMQ"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="619" mass="66388" checksum="B0E2B1C356B18BB9" modified="2013-05-29" version="1">MGLGEYFQEKLREPTPEEAEYAEHEKEHDDDATLGAHHGPSLTSWKAISIVGVTSTAMMLNICGVTSMNIALPSVGRDLGIPTSTLQWLMSAYSLTAGCFLLLFGRLADIFGRKHVFLLGDIWLIAFTIACGFAQQGVTIILMRAFAGMGIAATIPACLGILARTFPPSRARSIAFATFSAGAPVGAAFGLVLGGILTQYAAISWRAIFFVMAGIGALTLIGAWFSFPPDAPLAEDRRVDWTGALLITVGLVLFTFVLGQGEIAPQGWRTPYIIALLVVGLMMIFLFILWEYHVEFRTSRPPLMRLSLWARAGGRFAAVQLIGFLAWSAFATFSFWATLYYQEYLGLPPIQTMLRFLPMAVAGFSVNVVFALVSGHVPANYLIIIGCIGTGLANLLFAVINTGSPYWAFGFPAAILSVFGADFIFASSTLYGAKIARHHEQSLAGGIFNTVTQTGTAFGMTITTIVYDTVVWSQSAKEGVVLDQDGTNASPAAQLFGQRCAQWTSFGFAMASLAVAVVAPRGMGIIGGSGKKSAPSEEDPAEKEKDLEASPESAETSEDADVRRNVAETAEPQSPSAVRAATPHPANNTLAIQRGSPLMRVMTEDTVVDEDMDNDKPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFK2</accession>
    <name>M5GFK2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Molybdenum cofactor biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_113105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:31331"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the MoaB/Mog family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633286.1">
        <property type="nucleotide sequence ID" value="XM_040769564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFK2"/>
    <dbReference type="STRING" id="1858805.M5GFK2"/>
    <dbReference type="GeneID" id="63684626"/>
    <dbReference type="HOGENOM" id="CLU_010186_2_2_1"/>
    <dbReference type="OMA" id="ESPYPMI"/>
    <dbReference type="OrthoDB" id="4349954at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.980.10:FF:000001">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="entry name" value="MoeA, C-terminal, domain IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.10">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.190.11">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192:SF5">
        <property type="entry name" value="GEPHYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="MOLYBDOPTERIN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="MoeA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="MoeA N-terminal region -like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="7">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="MoaB/Mog" evidence="7">
        <location>
            <begin position="428"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU06392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="671" mass="71415" checksum="BAE2E5B96016270F" modified="2013-05-29" version="1">MPYKVAVLTAAADASADKSGPLLRDILASQGGDFNIAKSSIVPDDKEQISNIVKEWCSSGQIDWIVTTGGTGFGVRDCTPEAIAPLIERHAPGLAHAMMAHSLTQTALAALARPVAGTIDKTFIVTLPGSSKAVKENMDVLLGNGLVLHALDLIAGGSGKTVHAGMGTGHASTSTQPTDSVQVHHHHHHHHEHVSQNHTHHVPIPRTLLSHDPTQPVSLRHRESRYPLLDLDAAIDLVIKHSRLLEIVEKPFSVALSGHVLAEDVYAPQDVPNTRTTNVDGYAVRASDEPGIYRVLSPLLVPRNKNVPNGYIYRINTGSPLPPNMDAVIMVEDTKLISSVESDGDDNGEEVEVETLAKMEVGENTRAPGSDVKKGALVLQKGLVLKSGGGELGTVAFVGQKKVLFLMASATLYPSIVQVQVIRKPVVAILSTGNEIADVSGIGPGTDGEDWTGIWDTNRPSLQALLQGMGYDVVDLGIVKDDIKSHVDALTEGLLSADIIITTGGTSMGSTDLLKPVIERYLNGTIRFGRVKVKPGKPTTFATLEHHGKTKSIFALPGNPASALVCFYIFVVPALRTMGGWPASERKLPTVTVTLQDPCPRDPRPEYHRVHVHATSDGLNAFSTGGQRSSRVASLSGANGLVYVPPGTKEDHAPLPTGSKARAVLIGELYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFS2</accession>
    <name>M5GFS2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631272.1">
        <property type="nucleotide sequence ID" value="XM_040768088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFS2"/>
    <dbReference type="GeneID" id="63683150"/>
    <dbReference type="HOGENOM" id="CLU_2399629_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="93" mass="10272" checksum="2BD8020344632F0A" modified="2013-05-29" version="1">MLNNVLPPLVDNVKQSFVAVFADTNSPTPDILHRVKPLKASACNKFSQQGGLFDQRPTFAISSPVQGMLELFSPAFKWSMSSTKMHNHLQSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG07</accession>
    <name>M5GG07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631552.1">
        <property type="nucleotide sequence ID" value="XM_040771884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG07"/>
    <dbReference type="GeneID" id="63686946"/>
    <dbReference type="HOGENOM" id="CLU_1038366_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067731" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="27768" checksum="0D17932B17F444AE" modified="2013-05-29" version="1">MKFTSLVALAIGLTGTWAHKLPARGIHSVSKSILAGRADERPVFRRQLSATQCVTPCSGQTAQLNTLSECTTVDCVCSGMNTLSSDCQACLLQVDGLTAADWGATCADPGSLGDSQPTGVATSSPAQSPDPGSSSNTICGSSCSSASDSNDLTTILSCNPTDANCICTGLNQLSSGCLSCVLGTLGATQAQVQQQCTAELGGGGAVGAGAGAGGGGAAGPVGTTTAAVPEASGSVNDNTGGINLGSAAGGGSSGAAGSLPSTLAAKSGAGRATIGGLVSALVVVGGVVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD7</accession>
    <name>M5GGD7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thiolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_103801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632202.1">
        <property type="nucleotide sequence ID" value="XM_040767820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD7"/>
    <dbReference type="STRING" id="1858805.M5GGD7"/>
    <dbReference type="GeneID" id="63682882"/>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_1"/>
    <dbReference type="OMA" id="MSRVPMW"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="293"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="417" mass="44514" checksum="02CC1DFA5942D706" modified="2013-05-29" version="1">MLPLTLRRVPTLARALSSPVRRHAHSAAVERLLEKKDDDVVITFAKRTAMGRYKKGQYANVTIDELLYATFKATLEATGLPPSSIDDIVVGTCHPPSPLYVSRAAALAAGIPETVPIQTVNRLCSSGLMAIRTVANSIKAGEAEVGLALGAESMSQNPRPTPEISETVGRNAQAHDCIEPMGWTSEMVAQHYHISRATQDTYALRSHQRAEKALQAGIFAEEIMPILVGDHFAREDDMIRLGVTAESLAKLRPAFPGWGGEHSTAGNSSGIGDGVAVCVLMKREKAVKTGARIIGKWVGCSVAGVEPRYMGVGPIAAIPKVLALHGLEKEDIDIWEINEAFASQFAYCMDTLGLDGDRVNVHGGAIALTHPLGMTGVRLAVTGLHELQRRNGDLLCTSMCVGSGMGAAALFVNEAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGH2</accession>
    <name>M5GGH2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cupredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_103969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632377.1">
        <property type="nucleotide sequence ID" value="XM_040767855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGH2"/>
    <dbReference type="STRING" id="1858805.M5GGH2"/>
    <dbReference type="GeneID" id="63682917"/>
    <dbReference type="HOGENOM" id="CLU_053381_5_0_1"/>
    <dbReference type="OMA" id="ILEFHYH"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067713" description="Cupredoxin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="20149" checksum="EB217A0591DD1D2B" modified="2013-05-29" version="1">MHFSTVFAVAAAAFLPAAVVAQTTGANHQIIVGLNGTLTYTPANITATVGDSVTFVFAHGNHTVTQSTFAAPCVYTQNATAGTVGFQSGFQPIASNQSLVPSVTMLVNTTAPIWFYCQQANHCQQGMVGAINAVEGSAKSYDAFKALAMSGGTGTSASGGSSASSAPTSAPSQSTTSGSMVKAVCNAGVMLAAVGAMVAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGQ1</accession>
    <name>M5GGQ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_113898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632772.1">
        <property type="nucleotide sequence ID" value="XM_040769721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGQ1"/>
    <dbReference type="GeneID" id="63684783"/>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="IEAENEW"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="258" mass="27506" checksum="3E9EF77C8A1722B4" modified="2013-05-29" version="1">MSSTTPTVWLVSGANRGIGLGLVTELAARPDTIVFAGARSPSSVDALQALVTEHPGKVHISELISGDVDGNRAAVKEVERIAGRLDVVIANAGICDFMGPAMETSPEVMKEHFEVNVVGTLVLFQCTYALISRSSPQPKFIPVSSGAGSLKDGTRFFLPVMAYGASKAAENYLARRLWFEYPNLICFPISPEAVKTDLPTKALIANPRVADDPRLAALPLQSVETVASDILRRVDEAVRGGEEGPGFVKSDDGSVRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGZ4</accession>
    <name>M5GGZ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_92385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633237.1">
        <property type="nucleotide sequence ID" value="XM_040777067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGZ4"/>
    <dbReference type="GeneID" id="63692129"/>
    <dbReference type="HOGENOM" id="CLU_2326295_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067738" evidence="2">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU06343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="99" mass="10762" checksum="7D35A33949F2E35D" modified="2013-05-29" version="1" fragment="single">ARCLHLSLVHSLFPLSLQRPPNPPATKVLFPALPHRPQHVPRTLRSAQASLNRPSDIDISLNGRSTARRHRPSTAASDPQSAATTNTTTILLHKPQVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FND6</accession>
    <name>M5FND6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UbiA prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_111806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624158.1">
        <property type="nucleotide sequence ID" value="XM_040769289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FND6"/>
    <dbReference type="STRING" id="1858805.M5FND6"/>
    <dbReference type="GeneID" id="63684351"/>
    <dbReference type="HOGENOM" id="CLU_063928_0_0_1"/>
    <dbReference type="OMA" id="SKICTIM"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30958" checksum="A1E11099512D53E6" modified="2013-05-29" version="1">MASIRTLYLFTKADYHTLFFPITMFALVAGPIQQPIHILTTAVWIWMHQLQCNINNQLVSISEDKDNKPWRPLPAGRITASQAQQLHIVVASLSFLLSAVGGYKMVIASIAMNVFDVLYDQGRGSARWMSRIPLVVVMYGLFEYGSTRVITGFSELDDTARAAIMSSLAVIGTTAHIGDFQDVEGDAADGRSTVPIAFPRSSRIFTPLLVLGWSLFMANVWGLGVCSACAFVGLGALVAGRNWFYCDKAHDKNTYKLYSLWLLTLHLLPMNARWGVLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNQ7</accession>
    <name>M5FNQ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_119041</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624708.1">
        <property type="nucleotide sequence ID" value="XM_040770708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNQ7"/>
    <dbReference type="GeneID" id="63685770"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OMA" id="KWAMYLF"/>
    <dbReference type="OrthoDB" id="648285at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000119">
        <property type="entry name" value="MFS monosaccharide transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF73">
        <property type="entry name" value="METABOLITE TRANSPORT PROTEIN YDL199C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="25"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="509"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="564" mass="62249" checksum="78623BA740AEFA96" modified="2013-05-29" version="1">MSLEEGEQHQENKLRLVGDTLLYLITCFASLGVFLFGYDQGVMSGIITGPYFKAYFNQPTSAQIGTMVAILEIGALITSLLAGRVGDIIGRRRTLFWGASIFVLGGAIQSFTPTYGIMVLGRIVSGFGVGLLSTIVPIYQSEISPAEHRGKLACIEFTMNVGGYAFSVWTDYFCSYIPSHLSWRLPLLMQCLIGLILSLGSLLIPESPRWLIDTDQDVAGMSVLVDLHGGDVEDETAQMEFQEIKERVLEDRQNPERTYAIMWRKYRSRLLIACSSQAFAQLNGINVISYYAPLVFEEAGWIGRQAILMTGINAIIYVLSTVPTWYLVDRWGRRVILISGGSIMGLALALTGYFMYLDQPLTPNTVVLCVIIYNAFFGYSWGPIPWLYPPEIIPLPLRAKAVSLSTATNWAFNWVVGEGTPVLKDWIGWRLYPMHAFFCASSVILVYFLYPETKGVPLEEMDAVFGEESAQAASEPESETSSLVSRDRTDWATRATSLDGHPRGRGHEGDEDGDGQGEGGEDQAGDAGTEGDGDGDGEAYKPPARYTLWDRVLGRGQYRPVAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP35</accession>
    <name>M5FP35_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_25475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623676.1">
        <property type="nucleotide sequence ID" value="XM_040774176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FP35"/>
    <dbReference type="GeneID" id="63689238"/>
    <dbReference type="HOGENOM" id="CLU_927567_0_0_1"/>
    <dbReference type="OMA" id="CAPQPSY"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="28149" checksum="79FC34E1F411FAE6" modified="2013-05-29" version="1">MSNFFNQMKDQVEGAISNYAQNQGGQGNQNQGQGQNQGGQGGFGSSNNDDYGSNQSQAQSGQGGFGGNQGGDSGFGGNQGSQGGQGGFGSSNNDNYGSSNQGQGQGGFGGDSGSGNQGGFGGDSGSGNQGGYGGNQGGDSGSGQGGYGGSGGEGKHHHAHGEHGQGGQGGQGGQGGQGGFGGNQGGDSGFGGNQGGQGGFGSGNDSYGSSNQGGQGGFGGNQGGDSSYGGNQGGQGQGGFGSSNNDNFGSNQGGQGGFGGNQGGQGGYGSSNNDNFGSSNDSYGSGNQGGQGGYGGNQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPH6</accession>
    <name>M5FPH6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WSC-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_91746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623981.1">
        <property type="nucleotide sequence ID" value="XM_040777022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPH6"/>
    <dbReference type="STRING" id="1858805.M5FPH6"/>
    <dbReference type="GeneID" id="63692084"/>
    <dbReference type="HOGENOM" id="CLU_014722_3_2_1"/>
    <dbReference type="OMA" id="GVRWGCH"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF3">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067109" evidence="2">
        <location>
            <begin position="25"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="357"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="540" mass="56747" checksum="0AFA6AA530FB2DA4" modified="2013-05-29" version="1">MRSSGGIHTGLLGLLALAARPAAAFFRMGCGSSLVIERADPIVSPGKPSSHLHNIVGGNGFDFNMTYDDARASTCSTCEIVEDLSNYWVPTLHQQAANGSFIQVPLVSPMTVYYLQRYNSNNTTLKAFPPGFRMLAGNPNLRSYTDTLAQQAVSFVCLDYSGTSDQTNVFPTKNCPDGLRTQIFFPSCWDGVNLDSPDHMSHVAYPSGMDNGDCPITHPVRLVSIFYEVIWHIALFWPWPTDTPPFVLSCGDPTGTAFHGDFMNGWAEDVLQSAIDQCTNLSGLVSDCPVVTVRTSDQMNDCAMPSRVEETVGGYLDALPGCNPVTPGPANAVPVANCPVPAILPKGEASFLKPVPGWTALGCGLDEGPRILPNRYTNGAMTVEACVDICATNGFTYAGLEWAQECWCGNTLDTTRLGQYACDMPCQGDPSEFCGASSRLAVYSKGGAAPVSTSSSTASTVAAPTSSSTPASSSAAGSALSNVVSVPASSNVPAPTSSSSSSVSKPSNTPSAPSTPNNNGCPKPAFSEFGGDVHGRSHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPH8</accession>
    <name>M5FPH8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625478.1">
        <property type="nucleotide sequence ID" value="XM_040773594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPH8"/>
    <dbReference type="GeneID" id="63688656"/>
    <dbReference type="HOGENOM" id="CLU_1758748_0_0_1"/>
    <dbReference type="OrthoDB" id="3342035at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="15323" checksum="064E247BCAB0FFB3" modified="2013-05-29" version="1">MVLWTVPAAGVNNDQSAISQGIWADEGAKITSTVNFSGGQWTQTANVVSGGGSGNSKTEYFNMDGATDSHANFFVIESELDGQQTGDWNFDVTFTDISLTAATTDGVSALCSGATSHSDGNGFITISGYSLSSDGKTCNWGTMTLSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPJ9</accession>
    <name>M5FPJ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_118445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625518.1">
        <property type="nucleotide sequence ID" value="XM_040770582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPJ9"/>
    <dbReference type="STRING" id="1858805.M5FPJ9"/>
    <dbReference type="GeneID" id="63685644"/>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OMA" id="QELAWEN"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="110"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="408"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="60212" checksum="08359397B0A75841" modified="2013-05-29" version="1">MSALDIPGTDSEKEPFLPGIPLRERKATWKASRCAWILLLGLNAFYLASRVWPSNTSRCSPTTRICWAPCGPNIDCSQLIVPLDYTNLSSPSISLSLARYRATAPSLGSLIIEPGGPGGSGTQMVWNSGAKISRVVEGRYDIIGFDPRGINNSEPKIECWATEEERAVFHRAILKLPSDAKSSLAEVDAWYEVWAKGCSERSGEAIKHVSTAFVARDVDQLREALGQEKLMYWDACEYPVDGRSAIMWGKTSLDDTVHAFEAFLDTCASVGPSRCPLVKVEGTTAVDLRLEVEGLLMDLSHRPLPVTQGEHRGIVTRFGALSYLYSSLYRPNAEWPRLAEVLDALITQRNGSLLLQELAWENGLPPHDEEGTAVLCSDAVPANMISLEEWASQTREMVEKSFISGEFRSLYTLPCRTWLGRPKERYVGNFSQKLAHPILLIGGTHDPATPLRNARRLAHDMGDSARLIVHHGFGHTSTRHVSNCTTQAVRDLLLKGILPEAAETHCFPSKELFPVGNEFDVADVEEREILRAMRDIGMSVAARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPK5</accession>
    <name>M5FPK5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBD9-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_120069</name>
        <name evidence="3" type="ORF">DACRYDRAFT_95710</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795916">
        <property type="protein sequence ID" value="EJT96489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623387.1">
        <property type="nucleotide sequence ID" value="XM_040770931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPK5"/>
    <dbReference type="GeneID" id="63685993"/>
    <dbReference type="HOGENOM" id="CLU_118665_0_0_1"/>
    <dbReference type="OrthoDB" id="3385708at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011944829" description="CBD9-like protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="18689" checksum="60BAFA6C7135E083" modified="2013-05-29" version="1">MLSNIMTWIVSAMMLAWASSCAAIDIPPEPTRGSIDLNWNATSSSYYISLSLAPGPNIYSSTSGGALIGGVESYTSVDMFFNYTGASTGWTLWAVPTSYGGHVIDQPLTTVWEFGDIPVPEACAYTPITQIDQLTYPADFEWWGDCGMGGFPVFHSAAYGFEVSLNEPVTVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPS2</accession>
    <name>M5FPS2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DUF323 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_57088</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625638.1">
        <property type="nucleotide sequence ID" value="XM_040775414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPS2"/>
    <dbReference type="STRING" id="1858805.M5FPS2"/>
    <dbReference type="GeneID" id="63690476"/>
    <dbReference type="HOGENOM" id="CLU_006921_0_1_1"/>
    <dbReference type="OMA" id="FKHWHPT"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="8">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="8">
        <location>
            <begin position="237"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="DinB-like" evidence="9">
        <location>
            <begin position="469"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="7">
        <location>
            <begin position="673"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="7">
        <location>
            <begin position="815"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="981" mass="109357" checksum="CE9C479189182876" modified="2013-05-29" version="1">MNSGSEYAPTITDVRALSPLAGLALSSQIRAGLTQPKGKRTLPTVLLYSGSGLRIYDSLTAESKVYYPFSEEEALLTHRADEIVSRMGLHAQEGVMVELGAGALRKTSLLLRAMAKLASTQSEDTVPFTYYALDLEQEELERCLRLLMSTYGPELRGKVAAHGLWGTYEGGIEFIRTGGIDRCLDVPNHCGNDSSTVRSSTPPLSTAGSSLNDSSRPSTPPLATPSPCPRALSSEGEHPPLHLLFLGSSLGNLTRQAAAPFLASLPLRPGSRDTLLLGLDGRNEQWRVESAYSAKDYWTNEFLMNGLTNTARELGGPEFERERWQYVGRYNVEEGRHEAFYRAKKDMQVVLPGTPEEGELSVDIARDEEINIEYSYKYSSADVATLFSAANLRIIESYHSPNLNTETGQPLYTLYLLERPAFHFPLLPTLHPSADSQALFKRVPTGGVPTLDEWNELWKAWDIATVGMIPEPMMHRKPIDLRHKCLFYLGHIPAFLDIHLSRLFQEPHTQPEYFKHIFERGIDPNVDDPSVCHDHSIVPEKDEDWPTLDQILAFRDAVRMRVAQLYEHMETGEKACLRRVGRILAIVFEHEIMHLETLLYMLIQASGEPNGSLPPPGFATPPFASLAKEWDAFPPPSNPVPTFLLEEGSISIGHDDFEAEDYATADESWKETHEFGWDNETPRRLVRHGSVRIEVAPITNAQYREWWEGSGRTMPASWVLVDGEIHVRSSPTPIVRARTLHGPVAFSVAQHWPLQASYDDIAAFAASKGGRIPNELELRAFLDRTDAGEAANIGFKNWHPIPPQWDSIAQRGHNGGVWEWTSTVMDRYEEFLPSGVYPGYSNDFNDGTHQVVLGGSFATHPRIAQRRTFRNFWQHNYPYAWVGARIAYDMPQDIDAKPVAFAVGTDIHVDGAVLGQDESEGKANITVVVDGNADEKLESTPNVAPVVGVGIGDVLRATLDFVWWVSCRLVPDAFRKLTTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPS9</accession>
    <name>M5FPS9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_112619</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623477.1">
        <property type="nucleotide sequence ID" value="XM_040769452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPS9"/>
    <dbReference type="STRING" id="1858805.M5FPS9"/>
    <dbReference type="GeneID" id="63684514"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067178" evidence="11">
        <location>
            <begin position="26"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT96579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="467" mass="53247" checksum="366D796B59295383" modified="2013-05-29" version="1">MPLNLFFIAAGLIACLLILRRRADASPPGPRGVPLLGSALELPSKFPFRKFNEWSKLYDGWFVFSAIGQKFLVITNYDIAVDILEKMGTQTADRPTVPMAIYMARHIAFTLENYGDRWRRCRRLAHENFNIRALDQYHGIYELGTAKLLRQLSNIDPLKVPEELLQFSGTLTYEAMYGPESGGENVKQNIRKVWEMAETLGDAMSPAKFIINLIPALGMLPERISPWKQYGTRYFNEHDRFLMEMAQPGLTGQSDSGFVASCMRMRDRTEGISDAEIAWTSFALYGAGVETHINGAQDEVRTVAGDSPPTFEHRSKMPYVMAVMKEVLRWRPVLPAALPHTASQDFHYNGYRIEKGTYIFYNQWNMCRDPAVYPDYDVFRPERFLADPPAPDPPVFGFGRRICPGRNFARDLLFLAISNLLWAYHFEKATDADGKTITPSPEDIDGNILLHPKPFQFIMTPRREIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPT7</accession>
    <name>M5FPT7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625668.1">
        <property type="nucleotide sequence ID" value="XM_040771318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPT7"/>
    <dbReference type="GeneID" id="63686380"/>
    <dbReference type="HOGENOM" id="CLU_1917012_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="132" mass="14805" checksum="B014BCE39C684B3A" modified="2013-05-29" version="1">MHHDEIETALSCTMQLFKKMGSPGNAMPQRELHKRAEQFFTKGVQEPHEGGITTEGTLSDALFQILLGNEDLYEGDVNVVDINNDCAEHQDCHCMHPVKRARDVPEEEESGTTTPTCSRWDTSKEKDWSGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQG3</accession>
    <name>M5FQG3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626028.1">
        <property type="nucleotide sequence ID" value="XM_040773584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQG3"/>
    <dbReference type="GeneID" id="63688646"/>
    <dbReference type="HOGENOM" id="CLU_2073062_0_0_1"/>
    <dbReference type="OrthoDB" id="3024574at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067142" evidence="2">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="118" mass="13157" checksum="0C76D3DBD07BF99B" modified="2013-05-29" version="1">MFARIHLPLFLLALLLALMVLANPAPGQESLTNAQRFARGLGPKAPKRLFVPSNSDAKRAPAPEEENLTNAQRFARGLGPKAPRRLYIPSISDSAFVPHSPHAMPIRIQLPRKHERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQN5</accession>
    <name>M5FQN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040773415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQN5"/>
    <dbReference type="STRING" id="1858805.M5FQN5"/>
    <dbReference type="GeneID" id="63688477"/>
    <dbReference type="HOGENOM" id="CLU_557786_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="491" mass="55174" checksum="B887C36BBF304628" modified="2013-05-29" version="1">MSYGAQTVMDDRSRREPLFSREVSGYDSLQSTVGQTDVQEGARPGAPSCQFIRQYDSLHNTEYGTHFWTAEPHPQPKNTKFDLHSTTAHAGHSATNAPSHPGQQHTTLPSGHLLNPMVFPGIDRITHDPLPPYTSQEPVSRLENWWRQGGPSNFNPTNHPYPAQPPFDGESRIGGVPRFLKEDRRLPPPIPSRPMGFLGPRATNDRYVLPPLPELHPVPESSRRYTTQQKSSSWNQRPSSSNAFYPPPVTAPVAAYNHRVHEVIDLTRDDDDAGPAQPRDPPASELRSLNAATTSCQRRKEGKVKGKPKSKPKQLEYTDLPSIQTGFACPYPSPDDPRQRCHVLFSSRDVLQRHLGGHLKEERAMLRLGGEGFDQNSLVFGGVFAPGFPCQLCDYPFWRKDSRDRHQKIDQITNAVSCPKLGNPKNHGNWEQRHEEKREKYGLPEREVLRNAPMREGEGSQVARSTNTQHPGDHPPANNVPRARYTWAGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQW3</accession>
    <name>M5FQW3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle SRP19 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_110100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EJT99380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_052871_0_0_1"/>
    <dbReference type="OMA" id="SVWWPLS"/>
    <dbReference type="OrthoDB" id="2527451at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="272" mass="30404" checksum="A428C6705A2D0F44" modified="2013-05-29" version="1">MPPRAFIEEEFDDDTDLPLPTHSLPNTGTRGPLLQEIDSEEDEDVADEDDEEEYDPREEVIASGSGSRTSVPAQQQSGKGPLMNRETTKTWTTLYPIYIDAKRPLHKNERRIPRAKSVWWPLSSDMGEACARLGFNTLHDQGKRHPKDWENPGRVKVQFKKDGRLVNPSIPTKKKLLLHVAAYVQSKRPQFVPTPESLVPRKNARGMTKVPLPPSPAPAIPQRLPANSPIVETGMLVESMKQTLANEKTQQAQAQVEGTGGKGKRKVIRVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQZ6</accession>
    <name>M5FQZ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_111009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624926.1">
        <property type="nucleotide sequence ID" value="XM_040769160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQZ6"/>
    <dbReference type="STRING" id="1858805.M5FQZ6"/>
    <dbReference type="GeneID" id="63684222"/>
    <dbReference type="HOGENOM" id="CLU_028734_0_0_1"/>
    <dbReference type="OMA" id="DMADNTC"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051157">
        <property type="entry name" value="PDH/Transketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF1">
        <property type="entry name" value="TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="328"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT98028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="643" mass="69825" checksum="691D0496D17AF672" modified="2013-05-29" version="1">MADAESKFPIDLASYKNIALDPTKPSLTAQEKEAIQYNIHLLRDAIILFTATGAARGVSGHTGGPYDTVPEVVICRALFHHAATVPGSPQFVPTMFDEAGHRVATQYILSALNGDLPPEHLLHYRAAYSKLPGHPELGLTPGVKFSSGRLGHMWGHVNGVAFANKDKTVIMLGSDGSEQEGDDAESARLAVAKGLNVKLLIDDNDVTIAGHPSEYLRGYDVGRTLEGHGLKVARCLGEDLDSLWTGITTILATPGPAALITKRKMCPGVKGLEGSTHGHDVIPVKTAVEYLQGRGYGTAITDILLNIKPTTIPYVYEGSSRDNNANRVVFGEAVSDVLDGLSKEEAAEKVMVIDSDLEGSTGLKVIHQRHPEVFVTSGIMERGNLLAAAGFGFDKNKFGVFSTFSAFLEMCISEITMARLNDCNLLCHFSHSGVDEMADNTCHFGINHFFADNGLSDLHSYLYFPADAAQMAAVIKKVFFQHGMRFVFSTRSKVPYILNAQGQRYFEAPGYEFVPGKDEVILEGTDGYVVSFGEMLYRSYDAVLRARKSGVNVGLINKPTLNLVDESVLRKIGTTKFVLVVESQNQKTGLGSKMGTWLLERQLTPRYGYMGTVKEGCGGLQEQIPHQGLDPESILAKIKVLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRI5</accession>
    <name>M5FRI5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_39706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626653.1">
        <property type="nucleotide sequence ID" value="XM_040774466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRI5"/>
    <dbReference type="STRING" id="1858805.M5FRI5"/>
    <dbReference type="GeneID" id="63689528"/>
    <dbReference type="HOGENOM" id="CLU_000288_57_30_1"/>
    <dbReference type="OMA" id="YANCAEF"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9378" checksum="81A0ACD89B533AE6" modified="2013-05-29" version="1" fragment="single">ESTGWVCFVIEGHNFWVNSVMFSPHGSQIVSGSHNNTNKVWNMQMGAAISLPMEGHTSIVYSVMFLPNSSQIVSGAGNKTIRLWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRI7</accession>
    <name>M5FRI7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_58896</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624502.1">
        <property type="nucleotide sequence ID" value="XM_040775526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRI7"/>
    <dbReference type="STRING" id="1858805.M5FRI7"/>
    <dbReference type="GeneID" id="63690588"/>
    <dbReference type="HOGENOM" id="CLU_025866_1_1_1"/>
    <dbReference type="OMA" id="QPFSEFH"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="124"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="342" mass="38276" checksum="2197F0E12F986853" modified="2013-05-29" version="1">MRLSDLSPEPIRRGSSVLQHPSLVPVVRPLGQRINCIIHSYHFKAYPSPDKQSLVNAVIANLTVDGMISNLQKFTSFRTRYYRSETGKESQKWLLNRITEYASPSLKHLVNLTEFIHPWGQNSIILRIKGASKAATAEKGTVVIGAHLDSTNYDPFLPAPGADDDGSGTMTILEAYRGLLASNYTPVQDVEFHWYAAEEGGLLGSQAVAQSYAERNVNIQSMIQFDMTAWVKRGTREEIGIITDYVDADLAEFIRTLVNMYCSIPYVDTKCGFACSDHASWRKAGYRWGFCLGNALFNQDWTGLPTIPSRIDISDEFSFDHMLEFSKLAVGYIIESAGWANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRJ6</accession>
    <name>M5FRJ6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_117939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626673.1">
        <property type="nucleotide sequence ID" value="XM_040770495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRJ6"/>
    <dbReference type="STRING" id="1858805.M5FRJ6"/>
    <dbReference type="GeneID" id="63685557"/>
    <dbReference type="HOGENOM" id="CLU_063514_2_0_1"/>
    <dbReference type="OMA" id="IRNTVEP"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT99775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="226" mass="23946" checksum="9DE226ECBE7CF003" modified="2013-05-29" version="1">MTDLPPLKLDLGELSRVDGSARFASGSVIALASVTGPIDVRSGWEKPEEAFLEVNVRPLEGVPGTQAKSIAQTLKSALTPSLLLGRAPRTLIQLTLQALSPSSLPSNFAQPQISLCGKAAMMNAATAAFLDAGSVSMRGIVCACAVGTRNGGLVLDPTEKEETGAFGFLFRGTVSGELVWAEWEGEEGDWEKVAREARTGAEIVRDFIRAQFERAAGLAQEDEVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRM9</accession>
    <name>M5FRM9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein COX16, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein cox16, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_24439</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625276.1">
        <property type="nucleotide sequence ID" value="XM_040773683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRM9"/>
    <dbReference type="STRING" id="1858805.M5FRM9"/>
    <dbReference type="GeneID" id="63688745"/>
    <dbReference type="HOGENOM" id="CLU_131611_2_0_1"/>
    <dbReference type="OMA" id="VNMKDEY"/>
    <dbReference type="OrthoDB" id="5516033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130:SF14">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="130" mass="14928" checksum="05AB61A06278638F" modified="2013-05-29" version="1">MAAFTSRRRSNHLPFTGAIRKQPFLLFGLPFLTLIVFASFGLQTLTQTRYDYQRNKTTKVTKEEELQMSKNRKKVDIREEYFRLQAGESKIDLDNWEPVRIQRPEGTPEWGVPPSAPPSDPANKDASGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRS0</accession>
    <name>M5FRS0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">THO complex subunit 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_72082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624617.1">
        <property type="nucleotide sequence ID" value="XM_040775960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRS0"/>
    <dbReference type="STRING" id="1858805.M5FRS0"/>
    <dbReference type="GeneID" id="63691022"/>
    <dbReference type="HOGENOM" id="CLU_459750_0_0_1"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="594" mass="66126" checksum="908BF8F496C3B96F" modified="2013-05-29" version="1" fragment="single">MDILSITQEALKNWSDEAQRAKLLSGLSAHLTDISQSSTLASCLCAMLNALSSGAPGKTASLTPTQLAAFLAEIKQSFPSSSSEDGAAVTPEKSEYSELIIDLIWTLDTSLEDELAEITAAIKAEWQTAKDAVKADAMEVDVKEAKPAVVKDDKPPEKSSDPQTERTRLMCEAHKRALTQLLKELVMKSVITHTLAVERLDQPLLIAAGLVRNGAMYEKKTRQIRTSLFYKQTKFNLLREESEGYSKLIVELLSHHDQPASYTWHRMISLIGFFDLDPHRVLDLIFDVMESSIMTKWQWFLDLLREAGWAKHPIVPEGKGKERESEGAGEEWIGPSRFEGMTLEDILKRYEPCDSLHSTVDEKIMDVPAQLLGFKFCSHIYNQPNTPTAPRKELYLMVAILIREGVVSLPALYPHLYPTEDDMKLLEERHQKNLKELSVPKRTTNALTRAAPLSEEPDRPGGYRPRTTTAAATAAPAVAPTGPRKAEPPNHKMGLLRALLSVGALRPALWILTKHPWMFGPYSALADLYLRLLQCSLEPLYSRISMETLHNSVVVDISTPSNNSGSSANPKHTITDLAPEPPRTAGTTFDFFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRS3</accession>
    <name>M5FRS3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626813.1">
        <property type="nucleotide sequence ID" value="XM_040767514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRS3"/>
    <dbReference type="STRING" id="1858805.M5FRS3"/>
    <dbReference type="GeneID" id="63682576"/>
    <dbReference type="HOGENOM" id="CLU_035260_1_0_1"/>
    <dbReference type="OMA" id="WYYAVEP"/>
    <dbReference type="OrthoDB" id="205403at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107:SF1">
        <property type="entry name" value="WHIM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107">
        <property type="entry name" value="YALI0D24453P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="561"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="72236" checksum="EA8AD56F3C73443C" modified="2013-05-29" version="1">MPSATAPPPMSTPLTPSPPPSAHAPAKSQPAQGKPKAHPQEPEHPRDRWETAYVWAFLSRFCTAVIQKTQGLESVMDLEDAILMPEHTPLLETVFISLIRMCKPNTHTRLDAQTIPKTLLALMTERKMECMWYDIRNKVLRNPLDGVEDVFKAPWGLKLDILRQLVDWALVTDSGVRERIRAVRDATKYQSKPKEPTQEGEPGESIVLDPIGLDLERRRYWVLDHSGRMYRSLNPWKNVCPFTALTSSSTELRAEIGRLENELEEVEAARQLEASREQGRSRSEKPRHPVTKWENSMRTMVTRLKDEILPKVEQEEIRQTKKRKQLEVRQNYIALHELRESRTRRQRNKPRYVYDGVSEEEDNGDDFVEEDEGDNYENDTDEEPLPKRLRTSVRAPPVPTRSSGRLSAAQAAREAEGRKEWRGERRSSRLGGPSFDDAASVVEPSSPGNASEHTTATEQGTVNGTENGNTNDNDNGDGNGMSSSEKHPSDEPITPALLDADEVGAQQLFESVRLAKERKQDALRHIGGVSRVKDTEIIVEAPKGKKSGKFWFYAVEPVNHLGSLEIPDPPDIRRRPRKNSKRASSGKDNTAQREGSEEQPIMKDEDVDMDGGEEGSRTMTNGSGSRHDASEITTSPLPMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSP1</accession>
    <name>M5FSP1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxalate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_111204</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625132.1">
        <property type="nucleotide sequence ID" value="XM_040769190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSP1"/>
    <dbReference type="STRING" id="1858805.M5FSP1"/>
    <dbReference type="GeneID" id="63684252"/>
    <dbReference type="HOGENOM" id="CLU_030515_2_0_1"/>
    <dbReference type="OMA" id="GAPIMAQ"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067269" evidence="4">
        <location>
            <begin position="21"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="5">
        <location>
            <begin position="123"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="5">
        <location>
            <begin position="301"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT98234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="452" mass="49365" checksum="CC3D42F14B00A01A" modified="2013-05-29" version="1">MRILLSVVLTAAFTTPRSLAAVMEKRITYAEASAIAASNIAPALAATPTGAYASDDPNDSYYDLFQEETPEAVRTRVGLGPLGADILGPQNIPMEEQYPDLLAPPSTDAGTVLNSKWSFSQSHNRLQSGGWARQQTETDMPIATTMAGVNMRLTAGSIREMHWHTAAEWSYMLAGSARITAINADGRNYIQDIYPGDLWYFPAGIPHSIQALNDTNPEGCEFLLVFDNGAFSEDSTFMLSDWLAHTPKEVLAKNFHTDISMFNHIPENALYIFPAPVPPSIEVDCELADGPTGTTPSPYAFHLSQIPGTPLEGGSVKVVDSRTFTVSTTISAAEVTVNAGGLRELHWHPTQPEWTFFIEGEARITSFASSASARTFTYQAGDIAYIPPSYGHYVENIGNSTLKFLEIFNSPYYQDISLTQWLALTPPEMVSAHLQLPIDFVMSLNKTKAVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FSY6</accession>
    <name>M5FSY6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photolyase/cryptochrome alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_23046</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627538.1">
        <property type="nucleotide sequence ID" value="XM_040773068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FSY6"/>
    <dbReference type="STRING" id="1858805.M5FSY6"/>
    <dbReference type="GeneID" id="63688130"/>
    <dbReference type="HOGENOM" id="CLU_010348_2_1_1"/>
    <dbReference type="OMA" id="YTVFTPY"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000003">
        <property type="entry name" value="Deoxyribodipyrimidine photo-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="71"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="348"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="393"/>
            <end position="400"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="491"/>
            <end position="493"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU00641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="590" mass="66860" checksum="A3F45F6B5823ABF4" modified="2013-05-29" version="1">MNTNKNGKRPAPASSSPNKRARTIHGHSDPPEVKDKIASASAAAAVDAHSPLSILERALDRRPPGKLEGECVVYWMRMEDMRLKDNRAFSLAASIALEGKLSLMTVFLFSPGDYEAHDRSPRRIDFMLRNLRSLRASLSSLDIPLYTASIEPRHSLPQKLVDLLQEYSAVTVCANMEYEVDELRRDERALRLALEKGIRCEFIHDKCIVQPGKVLTKQDKPYTVYSPFLRNWISVVQGDSATLECATPVKKNTVSLTPKLEDLLKNPTPIPEYIPGFECKDKEKMALYWPEGEDVASEVLRRFLHTKARKEQLGGGKGVLASGEVDDLKHSRIMEYGEGRNRADKDSSSRLSPYLASGVISARECLRQVLALSGRKKLEASNREDGAQMWTQEVAWRDFYTHVLAAFPRVSMGRPFLEKFNTVKWETDAKNLQAFKDGKTGYPIVDAAMRQCNEMGWMHNRSRMIAASFFVKDLMLDWRLGERYFMQSFIDGDLASNNGGWQWTASTGTDPQPYFRIFHPVSQAAKADPSGDYIRQFVPELSKLKGNVLYAPWEHMPHAEFEKLGYPAPIVDHKEARERALRRYKNPGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTH7</accession>
    <name>M5FTH7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_53381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627843.1">
        <property type="nucleotide sequence ID" value="XM_040775170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTH7"/>
    <dbReference type="GeneID" id="63690232"/>
    <dbReference type="HOGENOM" id="CLU_2941661_0_0_1"/>
    <dbReference type="OrthoDB" id="3234349at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="60" mass="6741" checksum="196C8DFE4118DDB3" modified="2013-05-29" version="1" fragment="single">LITITPGPKEPNAKQLQPFLQPLVNNLLQLWQEGLVVKMPKHPEGVHMGNTTILQIFTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTJ4</accession>
    <name>M5FTJ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_25598</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795883">
        <property type="protein sequence ID" value="EJT96566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623464.1">
        <property type="nucleotide sequence ID" value="XM_040774234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTJ4"/>
    <dbReference type="STRING" id="1858805.M5FTJ4"/>
    <dbReference type="GeneID" id="63689296"/>
    <dbReference type="HOGENOM" id="CLU_001570_2_3_1"/>
    <dbReference type="OMA" id="YVNAFIA"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067165" evidence="11">
        <location>
            <begin position="27"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT96566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="485" mass="55455" checksum="A6E897B81BBB5C0F" modified="2013-05-29" version="1">MSVSWLFIPAALFACLLLGLQRKAEPSPPGPRGLPFLGSALDLPTKFVFRKFDEWSKLYDGWFTLSAAGQKFLVITRADVAVDILDKMSVQTSDRPALPMVRYMLRRMSFPFDNYNDRWRRCRRLAHENFNIQALDNYRTLYEHATAKLLRRLPDVDPMQLREELTQFSGALAYEALYGRDAGGVNQRRNIHRVWKLLEVLGDAASPATFLINLMPSLDILPESLSPWKQFGTRYFNENDKFFMEMAQPGLTGQSDSGFVASCARMRDRTDGISDAEIAWTSFSLYGAGVETTPYTLHWFVMAMVLFPEVYQRAQGEVSTVAGNRPPTFEHRSKLPYLVAVMKETLRWRPVLPAGLPHTASEDFLYKQFRIRKGTYVFANQWSMCRDPAVYPDFELFKPERFLADPPPPDPPVFGFGRRICPGRNFAQEVLFLAMANLLWAFHFEKATEPDGKVIIPSPDSIDGNILLRPQPFPFVITPRQEIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTL1</accession>
    <name>M5FTL1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625632.1">
        <property type="nucleotide sequence ID" value="XM_040770594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTL1"/>
    <dbReference type="GeneID" id="63685656"/>
    <dbReference type="HOGENOM" id="CLU_950019_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067301" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="28662" checksum="330296D6DBAE1CFC" modified="2013-05-29" version="1">MRLFLLLLAVVLPALASTKLQRAAQLSRSPLPLPIPEPLLRTHNHARQISSCGVNCTSTSACVPVCSSPSDVATINATSMCGSADAQCLCTGGDALTYSCLQCLLQSEDITPEQWDAVCAAYMPGGTTTKGATTAIATATAGAAQGTASAGTACVSACSSSSDQVGLAQIIDCPTGSTTCICQASYTFSNACLTCTLQATGISPAQWANDCQIATGLGIGGTSTSTTKLVAATATGAGGTRITSGGSGDGSTSGSSTATLPTGGTSSAGSRMAGDGLGLLFLGGLGLGLGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTW9</accession>
    <name>M5FTW9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_90564</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625812.1">
        <property type="nucleotide sequence ID" value="XM_040776960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTW9"/>
    <dbReference type="STRING" id="1858805.M5FTW9"/>
    <dbReference type="GeneID" id="63692022"/>
    <dbReference type="HOGENOM" id="CLU_1652099_0_0_1"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17858" checksum="701C9C51E373ED44" modified="2013-05-29" version="1">MLELTLGDYGHQAMDHLSSFYLGSTFNTRGGILTLILVILVTAHCLRRKRNSASRFPPGPTGVPLLGNVLQLPSKFFWYQLDTWSKLYGPVYTFWIMNRPIVVLSTVSASADVLDRQSGITADRAQSIKGAFYGIDQILSNKMHSYGCVHFCVFVTHIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU12</accession>
    <name>M5FU12_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rgp1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625877.1">
        <property type="nucleotide sequence ID" value="XM_040770555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU12"/>
    <dbReference type="STRING" id="1858805.M5FU12"/>
    <dbReference type="GeneID" id="63685617"/>
    <dbReference type="HOGENOM" id="CLU_005984_0_0_1"/>
    <dbReference type="OMA" id="VLGHDLM"/>
    <dbReference type="OrthoDB" id="1918at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="760"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="831" mass="89752" checksum="37A06298F7ADF0D3" modified="2013-05-29" version="1">MSSSDAGIQVTVTPAQSAFFAGETFTVSVTFTNAHRAAPPRSQPRSASAAQTHRRGVQSVSSVPLARPPTSPGSPQTANALTAGFLALEDTPQRKRRGLVGHEGLQNPRVFAVATESSARRRRFTPKSLSVSITANELVERLVGRTGNSTPSSPECEAGGAASLRGSNAPFASHNLSSRARNAALPIHPAHPHARKQSVQDFQAQEVSTPFSLSLDPIAEHSAATPPTPFAPSPLPPTIPVLDNNVHQQRDAFTARQIRPNARLGQSKRSGLANATTDLGLGKPSSIDISGGHQPRSAFSSTFSPPGTEVLLWAYVQLIGRIELDEGVVPFHIVDKLKDGLSANSAVGRGSMDIGSSHSPSTSFLTSVLLQKTPRSPFMRHQRASPSLFSSLPSFGLSSLFSPSRSSPFSSPSVNRDEEDALPTLDLQPSVLAVDLVLSPGESRTYTYTLALPPSLPPTFRGKAVRFNYELLVGTCHTASMTAGISLPSPGIFEEHRKKKVMKIPVRVYNFVSVENPQLCYDLMWSSHADKSIRQGRVDEHVPNMKKTRDMRHSSECKTPASVVAKQLVDEMTRSDRLHFAPEEEELWSCREAVEILTRNSRKVSYDIGKDGEQVAVLTLVKSSYRVGETISGVVEFNNSSRARVLKFSAFLEAHEQLPTAFVNARHLDLRRVHAEYHSTLTTNTAQLPFSLDVPSDASPAFRFAAVDFSEGEGGLRWRVRVCFLVVIAAGLSRHLVPEGYEDDWGTAWRASSTLTPLASRGMPSPSSMTSTPLPGSWNSSAGSPSSGGEARNGGSVDWQEVKAETVECDIPLAIWPGNTLFRPVETIFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUH4</accession>
    <name>M5FUH4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626781.1">
        <property type="nucleotide sequence ID" value="XM_040773241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUH4"/>
    <dbReference type="STRING" id="1858805.M5FUH4"/>
    <dbReference type="GeneID" id="63688303"/>
    <dbReference type="HOGENOM" id="CLU_503448_0_0_1"/>
    <dbReference type="OMA" id="IRRVGEW"/>
    <dbReference type="OrthoDB" id="3362817at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="541" mass="60667" checksum="7A8DF7BC1DE55DA8" modified="2013-05-29" version="1">MGADGSDLLRLSHTYQARLTPIPNPLRLRAFGRVDSLEAMAAEILDRTSRMRSHTVKLQCAAGVRPDLIQTISRISGAFIENSRESQVQITELDEESGEIARRLAERAGIEARDAERRPISAHISEEGETSDEAHSPFFTGHNYALYPFLVPGVLPWNMGYSNPFRVRRVGDWLPEDQRPKSSPLISARLASRNGVSKTLRETLFGGLPPLPLGFSRTVSATAGYHLISAPESRSLARVSLMPPIRDSFDLDTFFEWLKAGKGSTTFLPGVPPDIRAETLKPRRLIAMEDILIYRLRYQAREGSKEASRSPSRATPSDITDILDVQINFTLWHSHTSTNQLSETSGLEKAPLDRFTSECSTIPPRVMVARRGTTSSLDVLLPDRQFDIRLSVLDLIRITSRDLPQDLIEHLIDCRQAFSANGKLPESPFSVVVDGVTYFLMANEVVRTSQREESNVSRVFDGAAPHGETAVTIVEKVADRDVLDQQILQCCVHSSEPRLDIAWDKFLSQCDRITGYDQEEVLSFQHFTLPRHEETKQRMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUS1</accession>
    <name>M5FUS1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_90072</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626901.1">
        <property type="nucleotide sequence ID" value="XM_040776943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUS1"/>
    <dbReference type="STRING" id="1858805.M5FUS1"/>
    <dbReference type="GeneID" id="63692005"/>
    <dbReference type="HOGENOM" id="CLU_042324_0_1_1"/>
    <dbReference type="OMA" id="SCNYSSQ"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000015">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000107">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="54"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00070186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU00004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="343" mass="38438" checksum="216C70B7F89F3055" modified="2013-05-29" version="1">MSSSSKGKEVANGKATEPGYEMPWVEKYRPRVLDDVVGNTDTIDRLKVIARDGNCPHIIISGMPGIGKTTSIHCLAHALLGDAYKEGVLELNASDERGIDVVRNKIKTFAQKKVTLPPGRHKIIILDEADSMTAGAQQALRRTMEIYSNTTRFALACNQSNKIIEPIQSRCAILRYSKLRDQEVLKRLLEICEAEKVKYNDEGLTALIFTAEGDMRQAINNIQSTWSGFGFVNGDNVFKVCDQPHPVLIQAMLRSCHKGDVQGTMDKLDELWGQGYSAVDIVVTLFRVTKTFNELQEYSKLEYIREIGWTHMRVLEGVGTKMQLAGLVARLCKMNMKPELFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUS9</accession>
    <name>M5FUS9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA mismatch repair protein MSH3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 9">DNA mismatch repair protein MSH3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_89247</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628418.1">
        <property type="nucleotide sequence ID" value="XM_040776900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUS9"/>
    <dbReference type="STRING" id="1858805.M5FUS9"/>
    <dbReference type="GeneID" id="63691962"/>
    <dbReference type="HOGENOM" id="CLU_002472_7_3_1"/>
    <dbReference type="OMA" id="KMTMLYK"/>
    <dbReference type="OrthoDB" id="276261at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000870">
        <property type="entry name" value="MutS protein homolog 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF21">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="11">
        <location>
            <begin position="651"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU01521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="795" mass="88092" checksum="8863588AD3FF8CA1" modified="2013-05-29" version="1">MFSQGGSQRPQRPGTAFSRPSTARPPTRMSNTTVYREGEYGGNFVIAVIEGRGVAREVGIAALDRDTGRTVLLQVADCQTYVKTLHHISLHQPTTLLVLDTALSDRTTGRYGTGGGGPSLLVQALQDEFPGAAIEPVARKYWNENAGRDFIKQLIVEDEECPATLVAVHEKYFALSAACALFKYMESRRNAIFAIHSLRIQYIPVEGTMLIDADSARNLELINNLTHKKSNHSLFGILNDCFTPMAARILRANILAPVTNLNAINQRLDAVQELTDMEDRFTSIKESLRGLKGVDLDKLITALIVSEARPTTNVKIAEQRVGQMLTLRTAVRALKAVREALGGCRSDLLKAVERLINDDRIDQLDSLIAEALNEDAGIAKNGVHNKNMKVYAVKANYNRLLDVARETYKEDITEVYALHQRISEEHDMPLDLQWTENGFHFTVKKDEAPNGRLPKGFVDVNAKGPKWMCSTMELKKWNARVKDALNETMLISDQIIQDVLAEVIEYVAVLWKASEAIALLDMLWAFANASIIRPEFTSTLAIKAGRHPILEVVQPPGMLVANDVYCSDGTSFQLVQGPNMSGKSTYIRQVALLVIMAMIGCFIPAEYASFRLHDALLTRLSNDDDAERNLSTFAQEMATSAMILGMATENSLILVDELGRGTSPHEGIGICHALAEEMIQSKAFVFFTTHFNDLGATLGKHPTVTSLHLEVNTTRQTTSTGFNMVFQHKIRDGPMEEQNHYGLELAKLADLPDGLLATSARMAEHLAERERVRRAKSEGGKINTRRKLLIKVNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV24</accession>
    <name>M5FV24_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_118145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626327.1">
        <property type="nucleotide sequence ID" value="XM_040770532.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FV24"/>
    <dbReference type="GeneID" id="63685594"/>
    <dbReference type="HOGENOM" id="CLU_239257_0_0_1"/>
    <dbReference type="OMA" id="CHSSYVM"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="423"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="644"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="747"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="785"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="823"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="859"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="902"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="945"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1031"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1159"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1242"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1284"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1327"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1370"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1412"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1501"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1544"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1672"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1689"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1738"/>
            <end position="1749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT99429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1755" mass="193098" checksum="616C77D78143F986" modified="2013-05-29" version="1">MRWMKVGHRMNEGKCWKSSRTEGRNFLDTSVSCSYRESRRISTLFSAQRPVSTWNECQRSKMIRIFSQICSHTFGTFYAKGTILQSLRRCQRISAKIWREELLVCFTAMRYERLLKRPDKGLDYLYRAVLEDAFEPRTPALPNPNDSEEDAADHLEFFRALMGMVLTSFKPLPIGSITTLIELAQPSAPAAWREMLQSLSSLLSGVNVPGEPIRPLHISFSEFLQDRKRGGKFFIGTTGHHERLAVACLKLLKTRLHFNMGDIKTSYLSNMAMRSTNRFENKVPEELEYACVYWCYHLSRSTKEVEGDWPEMNKLVHHLFMEKILFWVDAASVANVTRDLSPGLTAVMTRLPEDMRPIAREARQFLLRFGRLIAESSAHIYISALPWTPRSSKLADLYQYRYPQIARLACPESTSWPALRHVIPNPGGYVSYLAFTPDDALILCVSTEGTIYVWNAATGHAEREPLRGASRWPTWINSSHDSTRVVSKSDHGTLRVWDLRTGVIISDIPIQPSAYATSQAIFSTTSHVMYASAEHMIKLWEATTGKFMWQSLTEHMHMVDLVAFSHDAAHIILHCQGTVVVWNAKTGETIGSREWGFVTSLAISNNGLHAVAGYFDGGVGIWHLENDEGSGLREARTTSSMKTRAGHIEQLASVAFLADETQIISASEDNTIVMWDAASGEKMGHSLCCRPGLGSAIRLWHDGGRTLIPSTMIILTLWNAETGKAMRKVLIDYLPISTSVPFALSCDATRVAAACDDGSIRVWDVATGEMVYACRTADLQEYWRIILSPDGSRMVTFSHDTRIRLWNVRNGELIVQPFSEEMVATVVFSDDSSRIVTGSAYGTIRVWDASTGEAIAEAMTGHTGLVGSVAFSRHGGWIASGSYDCTIRMWDASTGQGIGRPFVGHTDDVTCVAFSLDNSRIISGCDDGTVRMWDVSTGRAIGDPLTGHTERVDSVMFSRDGTRVISCSKEGRVKTWLAEGGDPTGIMVSIPGDIMSGIGVTSTGICAVATCSPSSVVVWDSETGEDVGQPFTGHTHRVRSARFSKDGKQVISVSKDEVVRIWGTECGDEIGAPFIAPAGPAVVGFWHDNGGTIVASAETSIKVWDASTEAPTSKVVCSLNHRVTQIVLSGDGTRIAAICRYGTVMVWAVKTGKAICLPLIDHGDDKLVLTFSHNGSRIVSKYWTGKVRLWNADTGESIGEPQYYPQFGSVAFSGDSNSIVFASEKAVKLLNADTCEILGDPLIRHADYVTTFAFSQDSTCIASATNNEIRVWNVDPNDGISQTLNHHMSGVTCVAFLPDDKRIVSGHYDSTIMMWDAKTGQPIGRPLTGHTKCVTSVAVSRDVTHLVTGSWDKTVRIWDVATGEAMGEPFTGHTSRATCAAISPNGKRIAYGSEDKTVIVWDVESGQPIGEPHRHTDEVLCVAFSAAGTHITSVTCDWKLWLWDVDTGQTVEKPLNGRTESRIPFTFAALSDDCTRLVSVSEKDTARLWDAETGQSIKYLLTGQASNIYRVAFSPDCKRVVSGSRENTVRLWDAETGQPIGTPLTGHTGWVSSVAFSGDGKRIVSGSWDGTVRVWSAETGAAIGQHAFTRTSGGEQELYATPPRSHGITSSALESLAPWHGPSEAGHGGGQLWRTVVRSQSSNAGVVHTNQFATLDACAAGDEITRSELKMAKEDEEAAADEEGRTQNEENDEENEDEEQEQHEEEQEEQEQEQEELNLDVVTFSKNNLSLSPHDEQQMTQPYVPTTEGNDGIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV83</accession>
    <name>M5FV83_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628578.1">
        <property type="nucleotide sequence ID" value="XM_040772691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV83"/>
    <dbReference type="STRING" id="1858805.M5FV83"/>
    <dbReference type="GeneID" id="63687753"/>
    <dbReference type="HOGENOM" id="CLU_2527405_0_0_1"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="84" mass="9580" checksum="F4FB21E2ACAC0AFA" modified="2013-05-29" version="1">MLTVMGVVIGFVISYGASISRLIWYHVPPRYCAPRDGVTGRIALGLVEAYAVALKHHLRGEMGVYYKDLYRLVWPESETLNPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVB3</accession>
    <name>M5FVB3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_94784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628623.1">
        <property type="nucleotide sequence ID" value="XM_040777242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVB3"/>
    <dbReference type="GeneID" id="63692304"/>
    <dbReference type="HOGENOM" id="CLU_1496162_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="180" mass="20044" checksum="089D90E303B054C9" modified="2013-05-29" version="1">MICQRSSSARIGADYRDTRWRTGSRCRGAAVEHPRARLRSEPCTSLRSNPVHLCLLFLLFPNLFQLSSQRSPTCSQRSPTCSQSSAPSSLLPTSAHAPLLHRLLDIDHCKQMEAGVSESEEGGPWKRLDSSVTGGRDRAEGWRRVGRTGSLPEWCCDLIPDQRAAVWRGRGRLWSSTIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVX9</accession>
    <name>M5FVX9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_55428</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626677.1">
        <property type="nucleotide sequence ID" value="XM_040775326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVX9"/>
    <dbReference type="STRING" id="1858805.M5FVX9"/>
    <dbReference type="GeneID" id="63690388"/>
    <dbReference type="HOGENOM" id="CLU_015166_14_1_1"/>
    <dbReference type="OMA" id="TTRFGAY"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="34"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="122"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="235"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="323" mass="35924" checksum="A10D121A6A1B6795" modified="2013-05-29" version="1">MSGRQVEDSTTDPKGIETSTQPPLARGPKKKKPYPFWLGGLAACSAAVITHPLDLTKVRMQVSGDKHMISSIRKTMQMGGGLRGLFDGLTGTIFRQATYSVTRFGVYDIIKREIHDGPEREMPMWKLIFSGCSAGAIAGLVGNPAEIILVRMQADKAKPAEQQLHYRNALQGLGRMIRDEGLSSTFRGVAPNVVRTILMNGSQLAAYDWFKQQLLRLPWFEDNIVTHFSASFCAVSVVLFREVREVARAVCSPADVIKSRIMSASGKGGSVMSAISNSFKTEGPMWMFKGWLPSWTRLQPQTILIFIFLEQFKKGVDWYRGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWD8</accession>
    <name>M5FWD8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_84732</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624599.1">
        <property type="nucleotide sequence ID" value="XM_040776695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWD8"/>
    <dbReference type="STRING" id="1858805.M5FWD8"/>
    <dbReference type="GeneID" id="63691757"/>
    <dbReference type="HOGENOM" id="CLU_018994_2_2_1"/>
    <dbReference type="OMA" id="WKRRVPT"/>
    <dbReference type="OrthoDB" id="406287at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="403"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="458"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJT97701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="474" mass="53856" checksum="717AFADADBE435CD" modified="2013-05-29" version="1">MAELKLPPPPRPGLIKTLSGTAINSLTAPFNEDGIGDWQAAFTLLDTIETYFDSHFDLLERRFKKTSDRLRSKASEALAARGPGRTPFEKELRQFRVKIAGRISSLYDTWHSSKVVRLKGKVSFFIGVQTVLISALIFGMAPEWIPFVYTVQMAYSFPYRVYTFKKKAWHYFLFDLCYYVNLLNMVFIWFMPQSKFLFQSCYLLSHGPIASAVITWRNSLVFHDAEKIMSLFIHFYPPFVFTVIRHYYPHAEERFPALVGLDTLSPWKALLLSGFIYTVWQGLYWKFIVIDRGAKISAGKRTTSFSYMLNDKRGIIGRMLRNIPPAYKEPSFMGGQLVYSLLTELPAVFLMYNSRRWSAVFLMIIFSVATWNGGGYYIEVFGRKFERELEALRKELAEASAAASNVSGSPGPSSPPSEAESQLTSPVIVASDIGFSPVNVPSDVKGEGEGEVETLDLSELHDERQVAQELKKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWU1</accession>
    <name>M5FWU1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_111436</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624814.1">
        <property type="nucleotide sequence ID" value="XM_040769239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWU1"/>
    <dbReference type="STRING" id="1858805.M5FWU1"/>
    <dbReference type="GeneID" id="63684301"/>
    <dbReference type="HOGENOM" id="CLU_044121_0_0_1"/>
    <dbReference type="OMA" id="APERMIN"/>
    <dbReference type="OrthoDB" id="5987198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289:SF6">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEKL-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="78"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="438" mass="49858" checksum="0F3B8DF63EEC8447" modified="2013-05-29" version="1">MLVNLTMKKQHPVTQDPTGDPGTSEPPVDLYVPPYGRTEAELNWSAVQPYLQSRGYMLRPRYHPGWVGSWVGTKKKPEKCVDSIGISEHGVVINAIRMRDGAPVLLKIWSSTSAQDGNELAVLQYFSDPARSGDPDNRCVPLLDTIDMTEWQERGVDYVLAFEVGGDAFVANPDFERFLQGLAYMHSHNVFHGDIHPGNIRMDAKNVFPKGIPGPYNFHPDHPLLMKQAKRFNTMQAPPKYYYIDFGSSTMFPSYEERKLVQFNAAAFIPPECKNDADALYDGFKADILQLGATITILIRACDRPELNWVIYALLSRMLKRDPEERPPIEALATAFREVLRDMSNREMRQRLSWTKKASPPFPLKVRYWFDYLGLWWQSFRYGLPDDILLNDPSELTPTRPTRRQAANTADREAKQRLGCIRETRTGSSASPTSNRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXQ4</accession>
    <name>M5FXQ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628171.1">
        <property type="nucleotide sequence ID" value="XM_040768543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXQ4"/>
    <dbReference type="GeneID" id="63683605"/>
    <dbReference type="HOGENOM" id="CLU_2223179_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="106" mass="11644" checksum="86756C4D026EFF3C" modified="2013-05-29" version="1">MDTDLLGPPTRIKTPRMGARGLGPQPSNAQQDNTSLLAPNLTYFLNGTEFCIPSTGNPEWDMDIWFLAYLKTHPHVLQHVEVTATQQVLASVPVGHGLKPWLQAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXV1</accession>
    <name>M5FXV1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625264.1">
        <property type="nucleotide sequence ID" value="XM_040773678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXV1"/>
    <dbReference type="STRING" id="1858805.M5FXV1"/>
    <dbReference type="GeneID" id="63688740"/>
    <dbReference type="HOGENOM" id="CLU_785323_0_0_1"/>
    <dbReference type="OrthoDB" id="5231159at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="353" mass="39764" checksum="225BE5D923C42AA4" modified="2013-05-29" version="1">MYNKAASNGLQTFGVARCQLRLGQIALKRREVPSAISHFGEARGIFQAFKFDPGTAEALEGLAFADWLRYKLPEARKHAEWSLKLREAQPDQLVISRSLMLLGDLDNTEFHVQEAEARYTRALEIRRGLATERPLAECLDSLSKLYAGRGELDRAELMLKESLKLKTDVDDEIGCAVTQFSLAKIACRRNQIPDGIQSMEKVLAAAREEGNKELSGSVLLFLGFVNRQLGKTELARNHLEEGTKIFLEELGHLKLLKLMAVAGLTILASIDVKENRLTKAEKWIHLAQDLADNTRSKPALQAVYAVRLELCSAQGNHREVEKMEKKIEQLKQETGNVLIEFSLRSFLRTFGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXZ2</accession>
    <name>M5FXZ2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_67296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628291.1">
        <property type="nucleotide sequence ID" value="XM_040775841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXZ2"/>
    <dbReference type="STRING" id="1858805.M5FXZ2"/>
    <dbReference type="GeneID" id="63690903"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OMA" id="HWEDDAW"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="300" mass="32778" checksum="276CC5D3DCE5CDAB" modified="2013-05-29" version="1">MSTKLVAVLGATGTQGGSVVTSLLAHGGYSVRAITRDTTSAKAQALKAKGIEVVSASLTDAPSLVKAFEGAYAVFGVTVPFTKDSEVLQGRNIVDAAKEAKVPLLVWSSLFSTSEASHGKYTTIYHFDQKSEVDKYARSSGQPTVIIHTGGFMENLIKFGQLQKDPSDANKWNIVYPVLRPDVLMPLVYITADLGNIVVAIIDHWEDDAWKSRLTKDVVVAAPYLASINDIVTLLKKLSGKEVVYVERPALDFEKVVYGFANEGYFRYPEQTILQELGVKTHSVEDYARVEVLPYIESAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYQ5</accession>
    <name>M5FYQ5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_106337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630060.1">
        <property type="nucleotide sequence ID" value="XM_040768247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYQ5"/>
    <dbReference type="STRING" id="1858805.M5FYQ5"/>
    <dbReference type="GeneID" id="63683309"/>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OMA" id="YFFDPAM"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF18">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="59"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="559" mass="60855" checksum="FBD61A1A834C51B1" modified="2013-05-29" version="1">MATPLTEKPSNGESKDVETGKHYNEKTFAALTSNIVVQDGEGEDFQETKVLKQGLKQRHIQMIALAGTIGTGLFLGSGGAITSGGPAGAFMGYLFVGILVSGVVISIAELSAFVPLSGGIIRHSNYFFDPALSFAIGWNTVYSTLISLPAEITAAAVIIDFWTTNVSNAVWITILGALLFITNLLFVRVYGELEFTFATLKIMLILGLIIMGLVVDLGGGPDHTRIGLYYWQNPGPFVQYLNIPGSLGQFLGFWATFSNAAYAYSGIEGISVAAAETRNPRQAIPKAAKRIFFRVLLFYVISILIVSMIVPSNDPDLLNAQGPGAAASPFVIAANRAGIKVLPSIINAVVLTSAWSSGNSGMLTGSRALYGLALEGHAPRIFKMVNRFSVPWVAVVSIGVFLCLAYMSVSSGAATVFGWFQDLVGSAALVLWIVITMVYLRFYYGCKAQGIDRHTELPWAGPFQPYAAWISCIMFSIILLTGGFAVFIKGNWDPQGFVGAYFNIPLIFILYFAYKFARRTKIVPLDEMPIREFIQIYKDNPEERDPPLRGWARLGFLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ09</accession>
    <name>M5FZ09_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_94788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628636.1">
        <property type="nucleotide sequence ID" value="XM_040777243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ09"/>
    <dbReference type="STRING" id="1858805.M5FZ09"/>
    <dbReference type="GeneID" id="63692305"/>
    <dbReference type="HOGENOM" id="CLU_009746_1_0_1"/>
    <dbReference type="OMA" id="KKGGWDT"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="283"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="618" mass="67815" checksum="1B4DBC45AADE676E" modified="2013-05-29" version="1">MAEALTLNPMSFRPNPSPPLKQRDRSGSRDSNSSSERLARPQQTFRSISGSWGVSGVGRGFDWRWDHDREDDANVVEDDEQSSSASKSPVSETAVLGVKDIDISPPSTSPRSLPPIETSHLPDQEPSIRTADTITPGSITATPTSPGIRPSRRAPSRRISLISGRHMPPPSDLNPEELPPVSPRISLSRTNSTASLALSVMMPLSRRNSDAEYLMNDQDPRTPLEKQEITYSPIYTPFNNKSPVLTRNASVSSTFSARSASAPSVASEYDDDSYDDEAALAGFGIEADAGRGAYGLVKRARRVDANGLPFGPPLIIKYVIKSRILADSWKRHRQYGTIPIEIYVLLFLTNVPNLLIPRPWHPSRKEFPPDLTREPVQQRGHDNIGKLLEFWEDAHYYYLVMPFEEPGTDLFDLVEANPAGLSPYDVRSLFGQIADGVEFLHSKGIIHRDLKDENVVLGPNGTCYLIDFGSCASGWREGKYWDTFSGTLDYAGPEILRGERYTGKPQDVYALGVIGYVLLVGECPYATATEAQAGLAPGSKAAAALEARCGPGFEEGHRDVEAGREGEENDGGGTLEDAGDLVRRCLSIDVDDRPQASRILEHRFLAGRKGWVGKEKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR4</accession>
    <name>M5FZR4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_16097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628277.1">
        <property type="nucleotide sequence ID" value="XM_040771162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR4"/>
    <dbReference type="STRING" id="1858805.M5FZR4"/>
    <dbReference type="GeneID" id="63686224"/>
    <dbReference type="HOGENOM" id="CLU_004591_2_0_1"/>
    <dbReference type="OrthoDB" id="2246127at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="627" mass="70551" checksum="AFCF852EA1593681" modified="2013-05-29" version="1">MQFYPVVGSTELREFWHGSLWAYKSSDACMTPMLQHESRPWFVDELVMCEDGNFFLPKRWVQIGSVNGEMGAFGHNIRLELIGPFSPIGESYIVPSVLHPDLAVRKFRLAKTFTYNWYELKDYIATGVLSFEEQYSELACRMPNPWRQKANGRHVYSLPLMIWEDDVSGNRSKQWYKHYNVCASNLAMPRQDMEVSSNILFLGTSPHATALELMEGLVIMLEELNLDGREAFDAVVEAPVLFTAWIAVLAGDNPMQSDLCSHRGLRANHFCRQCHAGGSQEFKRTPEGYASLFKTLAQCMPFILWDLVSADVLEAWVVIGLAGALLWQYDIEVKETYLDELRLAVTTLVHAMARLNPIKMISKPKMHILLHIVDNVRRFGPAVGFATERYESYNSVFRTRSVNSNHQAPSRDIATSFAHLDRVTHIINGRRWQDKQTGEYRAASPALLAELTVLRPLMKAIGCLVDEAPDARGFIQSSQPHSVIRLRDSAAHQHRPSLRGGDSRVSRGQSMIALNGDKVPVGAFVIFFSSVRRDKGLARVTEMLIPDTQDPAASGLPRPGMILLEIFGIGSPHESLGCPRLVSTGDFQVCIPQTSNRRSCAASMSSTTVLWEGVDRWTFDHDCKNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZX2</accession>
    <name>M5FZX2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_16138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628342.1">
        <property type="nucleotide sequence ID" value="XM_040771167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZX2"/>
    <dbReference type="GeneID" id="63686229"/>
    <dbReference type="HOGENOM" id="CLU_801732_0_0_1"/>
    <dbReference type="OrthoDB" id="2796825at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39113" checksum="588257654A3AE84D" modified="2013-05-29" version="1">METALAYLFAIWINALLHGIYLTLFFYWLSMPKDNGLALYFTVTSWLVFVFTNIDAARCLIMLIQGFWQSLDGEGPQGFFNSSAGWQFTLQEFNYLLLILVCDALMVYRVWRLYGSSRWIVTFPVVLLIAETVLRFVGDTYLALSIMAPFQETIAASLGTNTAVQVVITILLGYRLLFTEDLRLLPPEQRSRRFRLTRAIVESGLIISVCLIFNLAFFANGQVIHWAFNLSIPHLYAITSVAIVVRLRVAQKRQKEWDTVLHTVGHSSGTGYRRSAVAVRALQQTSVHEEDESEVGKPYPSRIRTGSGESLELGERPFGGRKGTTDFGTLRDGIFVHTEETRDSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G091</accession>
    <name>M5G091_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624090.1">
        <property type="nucleotide sequence ID" value="XM_040774111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G091"/>
    <dbReference type="GeneID" id="63689173"/>
    <dbReference type="HOGENOM" id="CLU_2183855_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="12038" checksum="BE4A36EC698BF12E" modified="2013-05-29" version="1">MIGWGDGRKGMRYCGFVRSLSINPPIFRLYPERRDLSTMGLSYLSRPVHGAVLPCVYYHVPMKMLLASVVACVGGWQSTNGGDPCLGSFRASAWFAPAFGKTMTCKVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0P1</accession>
    <name>M5G0P1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_79098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0P1"/>
    <dbReference type="STRING" id="1858805.M5G0P1"/>
    <dbReference type="GeneID" id="63691437"/>
    <dbReference type="HOGENOM" id="CLU_038526_0_0_1"/>
    <dbReference type="OMA" id="WDSTLHI"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU02314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="334" mass="36566" checksum="41CD209772FB4497" modified="2013-05-29" version="1">MSSSVEIELDNAPVDMVSSLHFSPATADHLLVSAWDGSVRLYDVTKDDQLVSVQHRAPVLDIAYPEAARAYSASLDGSVRIVDIEKGTVHTLGTHGNAARSVVWSESYNFLLSGSWDATVRAWDVRSPTPQILAAPHPERVYSMDADKERLVVCMAGRHVRVWDLRMLRERTGHKEPAQVRESSLKFQVRKVACMPEGEGFASSSVEGRIAIDYYDHSENAQAKKYAFKCHRTTVDGVENIFPVNALAFHPTYATLLSGGSDASISIWDIGTRKRIKQLPKFRSAVQAIAVSRGGERIAVGCGDGLEEGDKPVNASVFVRMSGDEAKPKPKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1D1</accession>
    <name>M5G1D1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_99657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629433.1">
        <property type="nucleotide sequence ID" value="XM_040777609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1D1"/>
    <dbReference type="STRING" id="1858805.M5G1D1"/>
    <dbReference type="GeneID" id="63692671"/>
    <dbReference type="HOGENOM" id="CLU_032339_0_0_1"/>
    <dbReference type="OMA" id="LMATHEH"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="572" mass="64304" checksum="76122028D0C71282" modified="2013-05-29" version="1">MSSLHLHPYAGSTTPRKNSGGSSELEPLRRVPSPAGIPPPTFTRPHSSMHPVRRATSPLPARPSSPLDFPAPGTGGRRTFRPRRRLLQAVACFALFCLLGALLSVDRRHVQKYIPATPSYGLGFYGWRAKRPKVASEGALRMRGQKSSIRTNLRTDNKYITAWFHAGWTNDVMMAFNLIHLAKLTGRIPILPPFPPDNAHLVGGHGLAAGFITFSQIFDLPRLAHDIGTPIVEMHELKSMQPHTIKIYGVEEGLLEEPPEMDVIGCWSTWLSTCDDGCIHARAAEEPGVYMLNVHYTPIPPSFRRAMPWEPITFENMTNIARPQPNPLLQYYLKPSNELTDFVKQRHIPLANPAPDEHIACFDFLYFVSETGLEVHQEYTGRTEAGRWAGAWGDVGRYARWTPELEDLARGYLRRAFKLPDRPGVTIPPFIGIHIRRGDFGKLCPQEQPDCLPTVADHVDRLSLIRGNLTERLGHAPEYYLMTTDETDKGFLYEAVRAGWTLVDHEKERTVERFGMWYPTLLDSVMLSMSTGFLGTSTSTLSIMARRRVEDWNNGFGLFQPFPGGMGPQFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1L4</accession>
    <name>M5G1L4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoesterase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_23755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626634.1">
        <property type="nucleotide sequence ID" value="XM_040773375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1L4"/>
    <dbReference type="STRING" id="1858805.M5G1L4"/>
    <dbReference type="GeneID" id="63688437"/>
    <dbReference type="HOGENOM" id="CLU_027977_4_0_1"/>
    <dbReference type="OMA" id="QLPQWAF"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF8">
        <property type="entry name" value="ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012045354" description="Phosphoesterase-domain-containing protein" evidence="3">
        <location>
            <begin position="16"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT99736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="48257" checksum="EA4DDEF65C8C685B" modified="2013-05-29" version="1">MAAVVVLAAATAVLGATAPAFAPPGAGPQFQTANYTGFSNGTLQNGPVVPGLAFDRFIQIWFENTDFAVANSSAVFQQLATQGILLSNYVAVTHPSEPNYAAVVGGDFWGMGDDNLHYIPNNISTVADLLDAKNISWGEYQENQPYDGFPGYNYTQANYLNASAPPYTYYVRKHNPLILYDVVANVPSRASRIRNFNDFAVDLGNNTLPQWSFITPNMVNDAHDTTIDFAADFITYWLIPLISNPNFNTNRTLIVLTFDENETYGDVNNVWTLLFGGAVPQHLWGTVDNTFYSHYSCISSVEANWGLGNLGRGDVNKTMSNVFNFMITEYNVSYTNEDVTNPPLTNLTGNIPGPLNPQYWIPFTAPVNSTGAGGGPTLFLPGTNMNQMAANSPAPVNLTALGEALPGSTPATSAAAGGSSPSPSAGTSGAVELRMGAVSLLLALTGVAAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1U4</accession>
    <name>M5G1U4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adaptor complex subunit medium chain 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_84734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624605.1">
        <property type="nucleotide sequence ID" value="XM_040776696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1U4"/>
    <dbReference type="STRING" id="1858805.M5G1U4"/>
    <dbReference type="GeneID" id="63691758"/>
    <dbReference type="HOGENOM" id="CLU_026996_6_1_1"/>
    <dbReference type="OMA" id="INVHFTI"/>
    <dbReference type="OrthoDB" id="870at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09252">
        <property type="entry name" value="AP-3_Mu3_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14837">
        <property type="entry name" value="AP3_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="194"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="442" mass="48212" checksum="8F9AFC192148FD00" modified="2013-05-29" version="1">MPLPSLPGLIILDSLGKPIIQTTFRTTPPAFPLLHIGAFNDALSRASEKEGEAGKEGVENVLYVPGAGGKGSALCWKQDGDLRFLCPVNEDLDPLFVFSFLNTFLSILRDYIGDISASRVRDNFDLVYQLLEEMLDSGHPLTTEPNALRDIVLPPSLLNKLLSAAGASSLPGSTTAMPFASPIPWRRPGVRYNNNEVYFDIVEQLEAIVGRNGAVLSGDVWGEVKCQCRLSGTPDLLLTFSNSRLITEPSFHPCIRFQRWTRDRALSFVPPDGHFTLLNYMVAPPPLAPHQVPLQLRPHISIGTNTGSFEIVFVSRAGKTLEDVKLLWPLGEGATSVQASMSSANGPANEKDRTSWGLDPLSKSLEWRIPVLPASASLTLKGTFSSSETHPRTSPAIQITYTMSSSTISGLKVESLKLVGAESYKPFKGVRGSGRGNVEWRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1X7</accession>
    <name>M5G1X7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99901.1"/>
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        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="111" mass="12876" checksum="9C69D7FE186EDBC3" modified="2013-05-29" version="1">MISCGRSPVLMDVHVYRVEEWERELEETEEMLPKWHSTLPSAQTESVCLPSIPFDNMWPDDELRLPLFAKKSFVGGVDFNKPLDDEKNSKMEDGPVRKWWFAEGSLDSMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2F0</accession>
    <name>M5G2F0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_71620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT97942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040775949.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G2F0"/>
    <dbReference type="GeneID" id="63691011"/>
    <dbReference type="HOGENOM" id="CLU_018398_6_0_1"/>
    <dbReference type="OMA" id="EWDDWME"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000077">
        <property type="entry name" value="HemK methyltransferase family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
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        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
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    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="227" mass="24690" checksum="53D28807063D55CB" modified="2013-05-29" version="1">MLPTPDLSHLTQDDFTVVYEPAEDTFILLDALEQDADLLQKTDPAISLEIGSGSGCVSAFIGQILGKRSAYFCTDINADAGRCTMATGEQNKVLLNVVLTSLVGGLLPRLLGNVDLLIFNPPYVPTDDEEASQAQMGRSISGAWAGGAHGMNTTQEVLRIIPTLLSQNGLFYLVAVRENNPVAIAHQAKTELGLTCDIILERRAGIERLFVLRFSRKNRNNSNIFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2S7</accession>
    <name>M5G2S7_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">DACRYDRAFT_21364</name>
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    <organism evidence="2 3">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2S7"/>
    <dbReference type="GeneID" id="63687421"/>
    <dbReference type="HOGENOM" id="CLU_2183850_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="109" mass="12304" checksum="53DDE98252D3B729" modified="2013-05-29" version="1">MLLAASILREDIPAAYGLLLLGFLSAEILCIPSLSYLRRIENVDIFSLRCTRTPVGWYSQRSFGHPFWSTSSFSRYKCKSSFLSTFGRYHGIKPSVPTSAPWTSAYLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5G350</accession>
    <name>M5G350_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_13856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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        <lineage>
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            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040771004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G350"/>
    <dbReference type="STRING" id="1858805.M5G350"/>
    <dbReference type="GeneID" id="63686066"/>
    <dbReference type="HOGENOM" id="CLU_311689_0_0_1"/>
    <dbReference type="OMA" id="ASMEESF"/>
    <dbReference type="OrthoDB" id="3246510at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="392"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="682"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="787"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU04646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="942" mass="107812" checksum="FC169945CEE6775C" modified="2013-05-29" version="1">MDDILEIDNEDLSWEKTRRHAPVPWNPNNSSALNGGGRPLQPPVRPAHSGTHSNVPPAPKPPPPRVPPGKGLGDYARGREQRVAETPRPNPPVSNHAMYARPSPGSPTHRAQVVHTSEFEGSGAIPDFPGSGYSFTTTYTEGMDRFPAASQFLLSGINRSGDVSYARPPPQPFQSNPATSGRENHPKADGPYDDRRNGRNSREADYEEEPDHSRHSNIDEHTNNDTSERNSHTRDYSDPRYLRDGSLVQTRRNSGDSTREPHVTQHASSAHQQPAGRRSDVRSDPVRSHNDNMPSHTTTRSSATAYPDSPIQTSGPVPFALPRADQSRANPVPSDLPLSPRARSPSFTSDISFEDNPRDLTEIMPAKDPLSYLIPALRAAKRREKELRSVTNRDKNTRLAKLQLERDDLEKKLEKATQDLADTKLKANEKMKRGSQLFNDMKKDLDNYKTISNLVESDFRKTHSIMPELQDLRRQIKDSLDVISPYIETGENSLTEQKLKTKILLAELKNAKEMVDHDYMEAKSTIGLLRDEMAHDKCMLASMEESFQNLIRLQGEDNGAVQEVKALREKIIEHDLEVRKKQEQKIIDTLLKGAELELTNKNLEEEIETLRALQKIAEDDLKLVITRQETKLLEQQQQLLRNEFQIKEGQRELEQSAERWKEEFKVIRASERRERQGKNDAILDKERRVLQLESEIRSYEETSQQVKLQLSEQSITRNTSNICLYRYTRLQDEIASLTERRKTSEAAKQKAEELLQAMSDQFDLRDAGAIADEDLSNRRAMELQLVVQDLTHKLDVAHNKLDELQKQLDKQRSEEAIKLAEVENELSHRREELQQQKTEYQTNYAERMDACEKQRDELLRRSTTMRERYWTKDLTSAEMEFVEVIKDDIEKAHELEGTRTRNAIKKLQSENEKHIVKIADLERSLKIEMAKARESLPLTRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3A4</accession>
    <name>M5G3A4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768249.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="194" mass="21472" checksum="368631B60000D92C" modified="2013-05-29" version="1">MPRISDLTDTPSLSIFLKQAPSPESSDSPPSDSLFLNFFNSCFPPLCSHPLHTSPRMAGVHHTHNHNKSNAMITDVLLPTNTSSKKGKGNKENLPALFHDATSVVLALSTEDDLNEDPIETLVEPKKHALSVSDIEEDKPPPKHTKKQPLKQLNNGLDLQKFLSKKKSKKEELIEANVRIVEFGAIIMSMKDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3L8</accession>
    <name>M5G3L8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_106434</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630163.1">
        <property type="nucleotide sequence ID" value="XM_040768267.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G3L8"/>
    <dbReference type="GeneID" id="63683329"/>
    <dbReference type="HOGENOM" id="CLU_000604_27_6_1"/>
    <dbReference type="OMA" id="CHIRPKE"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="568"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1045"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1084"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1177"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="339"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="751"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1364"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="428"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU03269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1621" mass="178585" checksum="A348E4BCCD8209D3" modified="2013-05-29" version="1">MSELDALERLLARVSQSGMGSMHAFDSGDGCSAKSIWLDPRFIPAYASALLLLLFSNRSRKPQPAPLSLSEPESSLLNRANEFVKLRGGWVIYVFNVARVFGASALVGLTIAAVVLSSGQRPEVVSGTDAQFPLGGGQRWDRMWDCTGRAEVALLVAYAYATLLSLLALVLTGAARASCSFHASWILFIQFLVFFWRNFLPLTTFTGIPADNTLPWLLWTRGSFVALVGLAIPALVPRMYVPFDPSNPAPKPAPEQTASIFSFMFFLFLEPIVFTAWRVPQLPYDRLPPLPDTDWSDNLRARAMDKLDPVRRRDMGKRERHIFFGLMDVFRWEYTRMSFFLVLEVMCRFLGPIGINRLLTYMEHDGEGATMRPWVWILFMFLAPTLNTLAFNLYIFTSTRMTVQAENVLTQIIFEHALRVRLTDESIISASPAPTPGTSTPGAPEDGAETPAAHAPSASGTETATLVDTERDAEEGSSTPPSAPPAAPASTNGTDKGKDKDPGKDKPDAAAPSAPPNTATHLSAKINNIFGTDIGNLIDGRDFLFMILDCPFEVILCIWFLWVILSWAAVVGMLFIIITLPIPGMIASRIQDAQRKMMQKTDLRVQAITESLGIIRMIKMFGWESLVRGQVGTVRDEELYYVRLRKILGMLNNIISGMLPMITMIITYAFYTLVLGKELDAARVFSSVPVFDTLRHDMAGAIMMLTNIIKAKVSLDRVSDFLRSSRLLDRYRPKTAETALVVAPAAETDVVGFHNATFTWTDPADGSLKPGQRNFRLHIQDLVFKSGEINVIVGPTGCGKTSILMALLGEMHFEPQGVDSWFSLPRGRGLAYAAQESWVQNDTIRANILFGNPYDEVRYKKVLYQCGLEPDLTMFNAGDAAEVGERGLTLSGGQKARITLARAVYSPAQTLLLDDVVSALDVHTARWVVDKCLQGDLIKNRTVILVTHAVALIAPIATNVISLSTHGRILSQGPLAATLTSDAALREELKESKDAMNVIEALPGDEQKPADKSSDGKLIIKEEMAEGRIKWASVKLFTDAFGGPVYWILLTLGYVIILSLDIGGTWWLGRWSAAYESPSSGVNVIYYLTVFILVIIFQECTWLIMQLVHALVSIKACRRIHNALMDSVLASTLRWIDSTPVGRIVSRFTQDVREIDGSLTGLAQVILQQSVSLIMKFIVIMVISPIFSIPGALIIVAGLTLGQIYIAAQMCVKRLRSNWRSPLYNHFNAAVSGLISVRAYGAEESFKAELRQRADAYSRPSRTFYNLNRWINTRADLLGAAFSSGLATYLLYVRARIGASTTGFSLTMAIEFSSMILWWVRVVNMVEISANSLERIRDYLVIDHEPEITEKGKPPAYWPSSGSLQVEDLSARYSKDGPLVLQNITFEIKSGERVGIVGRTGSGKSSLALSLLRLIPTEGKVYYDGQLTEGLNLDALRNNLAIIPQEPTLISGTLRFNLDPFSQHDDAVLNYALRAIGLLTENGAADGTNLTLDSTVANAGSNFSVGQRQLIALARASLRGTKVLILDEATASVDAESDSVIQTSIRTELHHATLITIAHRLLTIMDYDKIMVLDAGKLVEFDSPMALLQNEKSYFRSLVEESGDKEKLISVAERGRSSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G431</accession>
    <name>M5G431_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase/thiol ester dehydrase-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631915.1">
        <property type="nucleotide sequence ID" value="XM_040771992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G431"/>
    <dbReference type="STRING" id="1858805.M5G431"/>
    <dbReference type="GeneID" id="63687054"/>
    <dbReference type="HOGENOM" id="CLU_028690_1_0_1"/>
    <dbReference type="OMA" id="IHYDRRY"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039569">
        <property type="entry name" value="FAS1-like_DH_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13452">
        <property type="entry name" value="FAS1_DH_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1-like dehydratase" evidence="2">
        <location>
            <begin position="99"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="340" mass="37414" checksum="EBECE25B51AEEBED" modified="2013-05-29" version="1">MHLPRPTLAPLFSHPARVNALRPQALLRGAHQPSGEPAPISAAAVAAWAESVLEVPHHAHDNITLSTALKLYATLPTRSGPIYSTPPPTVAGLPFGPGHHLVLFPPIAPEAELNPDGTEPMFTPPLPWSRRMWAGGEMEWVPDNELRIGDAVKCESAIDTVEEKGWRDDKPKLFVWQRHKISNNKGVALVDRRAHVFQPMGVDGEVSQPRDKPNPDLPDPDFSVSFTPSDLTLFRFSALTFNAHKIHYDAAYAKSEGHPGPLVHGPLTALLLLEAANFLLPPSGRFLRFRYRAVRPLVVGKEITFLGSWRPGARGELTLWAQDDEGRVGMWGEAHMTGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G459</accession>
    <name>M5G459_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630358.1">
        <property type="nucleotide sequence ID" value="XM_040772205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G459"/>
    <dbReference type="GeneID" id="63687267"/>
    <dbReference type="HOGENOM" id="CLU_2831142_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="66" mass="7024" checksum="20B7B6A7FFFFE327" modified="2013-05-29" version="1">MGMSCPPCGPVAPMGILPRLRRRAEYAHAACDPRAPGASLFPSRRGLGPARLLAIYERALLPPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G464</accession>
    <name>M5G464_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_104944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631950.1">
        <property type="nucleotide sequence ID" value="XM_040768003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G464"/>
    <dbReference type="GeneID" id="63683065"/>
    <dbReference type="HOGENOM" id="CLU_787597_0_0_1"/>
    <dbReference type="OrthoDB" id="10486129at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="352" mass="38328" checksum="C2A15FC85BA29885" modified="2013-05-29" version="1">MAGNTRSTPDDVLPRRPSSISHIQQFLRKRFSLKEDFPVRTRRASGLTEHFNFFRSRGPSKTAPSAMETVASMSPITPSSPMTAADISLRRRSVSFAPKTPSRLAQSMLPLSPPITPNKESFSDAQVDDRISIELPHHATALSNAPRPLSFAASSLKRGRKPPPAALDLSPRKVLTPATRTKQDVAEKKKPGRLNVKILESIARRGGQVPPAAVADQNALSATSPPNMRPVGTPKEEFGAQIGMLGLGMVASPLPLSALSPRPPAARSGTANVSHGQASAAAPITAIHMGRQMTFAPLPPEPDELGRCTLIDEEGEPSMVFPREIQDWIYMPWVYWGMICGRPFNLWFEPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4B0</accession>
    <name>M5G4B0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_90725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625480.1">
        <property type="nucleotide sequence ID" value="XM_040776968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4B0"/>
    <dbReference type="GeneID" id="63692030"/>
    <dbReference type="HOGENOM" id="CLU_1054045_0_0_1"/>
    <dbReference type="OrthoDB" id="10362352at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="271" mass="30160" checksum="05F76A0AEC113EED" modified="2013-05-29" version="1">MGLIKISGDYSDLLTVFPLPKTLLKSILPKDVYDGLLPVPANYGLRADEHLVMLHLGRQKTGPPFYRFNAQEAKVEIPFIAPPFSSSREKAVPSVYKHSLWTDSLLLATSARMTMGLRTEKAVFDPPNAPGDAGSLRSLTDGAVEAKYEVKGKVSWFGRKDKWQGELYAQEKETVSTAGIWWFGEYAGGSLCQFPMTAKRENVPYKATIRLHLPSIQLGSSPLPASPALRENYRIEGEWLVLQGVTTWWNDASWELNGPHKAAEVEKQLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4K5</accession>
    <name>M5G4K5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YEATS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_110576</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625570.1">
        <property type="nucleotide sequence ID" value="XM_040769082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4K5"/>
    <dbReference type="STRING" id="1858805.M5G4K5"/>
    <dbReference type="GeneID" id="63684144"/>
    <dbReference type="HOGENOM" id="CLU_395344_0_0_1"/>
    <dbReference type="OMA" id="GSTHEWS"/>
    <dbReference type="OrthoDB" id="1741717at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055127">
        <property type="entry name" value="YEATS2_3HBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058706">
        <property type="entry name" value="zf-C2H2_AHC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22951">
        <property type="entry name" value="3HBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25909">
        <property type="entry name" value="zf-C2H2_AHC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="4">
        <location>
            <begin position="373"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="697" mass="76611" checksum="73647532A94168D7" modified="2013-05-29" version="1">MPSVLGKRKRGSVQFDRGGSRPVAAGVGKQDASKAIVRAVEEQLDLERAMKLREIKATEARIAWAQTVVEGIEQGAGSSFSDGSRVKAAALLSYWSIGSAYYTWTRPRAPNHAPVSTNLPGVPLLPPPPPVDFPLLSPDLRASVQSIISKGHKPLLVKYVLDTCSEFVLLVLACPVCKRADLSTVQGFYNHCRLAHQLTYAGHSECIEASGQRVTKEDILSVGLDDVEIKGTGIPSIQRLFQRAVGMQPSAPAPVPQALDQIVQAHTPLSPSPAAVDTDLNKTLGLHDETPALAQFLGTTARRRQIKVFDTGEEIDVVTELPEPRRFRWLYRPRGVPPEEEMLDTAIPHRVDNPPPSTIPQAPIPTVTNPHEKQSRFHISRRIIIIDRSRFIPLSRRHGNVDGSTHEWSLSIIAPSYMPHLSTFLQEAHITVPSNPQTHTFSDAPYTAHGKSSAPFLAQVRLTWAGTQNKDTNTTHWVELDSAKSGAWVLGEQQVLDIKLDKETVFLPVREDTEREKQREAEERAEAAAAAAAVAAAAAVLDKPKLLVQKTLESLLPSFPLTMSDVKGKKAPLVPYTVTTTRRKFRTFTIGRQRAIEWQRARCLRLAAQQDLLNNSEFEARASLTTGFVLQWLRDRAGFRRMPIPDPSKAKPNANGRVNAINGKRANTKIQEFSFPSIGFIGGQSGSSIRPTVQGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4P3</accession>
    <name>M5G4P3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627729.1">
        <property type="nucleotide sequence ID" value="XM_040768755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4P3"/>
    <dbReference type="GeneID" id="63683817"/>
    <dbReference type="HOGENOM" id="CLU_1796411_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="144" mass="16692" checksum="E1B0E433FCFDC39A" modified="2013-05-29" version="1">MTLPCIVLLLTPTRLRTRRSALLSRINTLQDIISALLKEKALPQSDGDRALVGLAEISTALEHSEGSRVCTLWYLWQAESRLDALEEQHEAAITAWRRWTGREVNAETLPYLDRRLSERVTREKGRRDRRDEDEKDFEEEMGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4W6</accession>
    <name>M5G4W6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_21188</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU03689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040772280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4W6"/>
    <dbReference type="STRING" id="1858805.M5G4W6"/>
    <dbReference type="GeneID" id="63687342"/>
    <dbReference type="HOGENOM" id="CLU_060400_1_0_1"/>
    <dbReference type="OMA" id="GHIQLNL"/>
    <dbReference type="OrthoDB" id="1109245at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_eS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="24"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="244" mass="27471" checksum="EEBE87D2578F8352" modified="2013-05-29" version="1">MLDKLSGTYAPRPSPGPHKLRECLPLVIFLRNRLKYALTGREVNSIVMQRLIKVDGKVRTDTTYPAGFMDVITLEKSGEHFRLLYDVKGRFTIHRITPEEATYKLLKVKKLAIGAKGVPYIVTHDGRTIRYPDPLIKVNDTVKFDLETGKIVDFVKFDTGNVAVITGGRNMGRVGTIVHREKHIGGFDIVHVKDVLDRDFATRIGNIFVVGEGVKPWVSLPKGKGVKLSIAEERDVRRKQREAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Y1</accession>
    <name>M5G4Y1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627809.1">
        <property type="nucleotide sequence ID" value="XM_040772945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Y1"/>
    <dbReference type="STRING" id="1858805.M5G4Y1"/>
    <dbReference type="GeneID" id="63688007"/>
    <dbReference type="HOGENOM" id="CLU_1767989_0_0_1"/>
    <dbReference type="OMA" id="TERDAWY"/>
    <dbReference type="OrthoDB" id="544277at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="17191" checksum="9AD383D0665F56F3" modified="2013-05-29" version="1">MWLPADRDVGSTWLALRSGLWKSWFRWGWTGIQRMDYQYTPRCEKVFRQEMERRGLEMKDAWYLVNICVDPAEQGRGYTSLLMSAANSRWPEKPMLLESSTPKSRDVYLHLGFELLEQVNLGRGEVTPEGVLGEDREGITLWCMIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5A0</accession>
    <name>M5G5A0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_115161</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630743.1">
        <property type="nucleotide sequence ID" value="XM_040769944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5A0"/>
    <dbReference type="STRING" id="1858805.M5G5A0"/>
    <dbReference type="GeneID" id="63685006"/>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_1"/>
    <dbReference type="OMA" id="NYNFLVH"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="36"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="277" mass="30817" checksum="ACEC5F5029739921" modified="2013-05-29" version="1">MSSLLTISSSIKLSSGYLIPRLGLGVYKNDDPTLACEAALAAGYRHVDSALGYKNEKAVGEAVRRSGIPREEVFVTSKVHSLRHEYEEAKAAVEESLSNFGLPYLDHLIHDPKSGKEKRLETWHALVEKQKEGKLRSIGVSNFGVNHLEEIKDAGLPTPAVNQLELHPWCQQRDITEYCAANGIVVEAYTPITRGKYFDNPTATRISQAHNKTPAQVFLRWSLQRGFVPLPKSSQPDRVRAKAQLYDFDLTEEEMNTLDDCDMGEAGAVTWNPVNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5A6</accession>
    <name>M5G5A6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625835.1">
        <property type="nucleotide sequence ID" value="XM_040773522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5A6"/>
    <dbReference type="GeneID" id="63688584"/>
    <dbReference type="HOGENOM" id="CLU_2440810_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="90" mass="10744" checksum="0744A84B0F702CDD" modified="2013-05-29" version="1">MEEIQVFCMNYENPAVFTMIRHRIVNFTAELTASRSGRVSQRYRSDLAELRNLHAQGYCGLHHRLHQRRKMVFVQRCQMLNNVQHRIPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5H6</accession>
    <name>M5G5H6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627964.1">
        <property type="nucleotide sequence ID" value="XM_040772988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5H6"/>
    <dbReference type="GeneID" id="63688050"/>
    <dbReference type="HOGENOM" id="CLU_103877_0_0_1"/>
    <dbReference type="OMA" id="YIHYRIT"/>
    <dbReference type="OrthoDB" id="2538281at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067488" evidence="1">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="239" mass="25815" checksum="21F9265AAC2737A6" modified="2013-05-29" version="1">MFTDLTLFVLVLGLMGQKNLAAAVTTLGDGTAYESGKVEGMTWQASGILTQGCTDSVSKIDDCYEMTLSSNPNDNLDPGNWTARQRNELHFPPQADGSTWNYQWKHYLASGVGSTTHFFHMMQVFSTMDDGPLVTLDPISGAVRITDYERGCNPCGPTYSPLSSWEGRTTMHEMTLTSGSNGNLQYAVSDASTGAALISYSVSGYMGGQTYVKFGTYRATEDITTGVTAYVGDFASSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5P1</accession>
    <name>M5G5P1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_22898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628014.1">
        <property type="nucleotide sequence ID" value="XM_040773004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5P1"/>
    <dbReference type="GeneID" id="63688066"/>
    <dbReference type="HOGENOM" id="CLU_2009344_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="13496" checksum="8A392B27BEC67D2C" modified="2013-05-29" version="1" fragment="single">MGCVSREEFAAVKEENERLRGMLQTLSSRMELLERSEDSNSFSRDTTLASPILPTSPLGSHHSRSPDHVLKTQDSAFGPSFSPSSSSLLTAASALENSRAYTDRSILAFGRALSTELNLAIHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5X5</accession>
    <name>M5G5X5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_108518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628084.1">
        <property type="nucleotide sequence ID" value="XM_040768669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5X5"/>
    <dbReference type="GeneID" id="63683731"/>
    <dbReference type="HOGENOM" id="CLU_1234987_0_0_1"/>
    <dbReference type="OrthoDB" id="10427906at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="224" mass="23054" checksum="B2992F3167C01BED" modified="2013-05-29" version="1">MSNATASSTLDVLASDPSITYLPAGTWNTTNFYGNLTYAYGNVQILYTFSEPATGIEWWGSKSGSGGNAEVCIDCPLNSTSGVLVDYTDPSAGSYVPEPGMIAAWTNLTYDIHNITIYNIYDPQASNGQGGYGYIYFEGFELTGTDGTNAGNGNQPSFVSAPATSTSASATSSSPATVTVTDFVTVTPTASPSATSSSAAKVNSNRLGLCFAVLAIIGAVCASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G606</accession>
    <name>M5G606_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632575.1">
        <property type="nucleotide sequence ID" value="XM_040767885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G606"/>
    <dbReference type="STRING" id="1858805.M5G606"/>
    <dbReference type="GeneID" id="63682947"/>
    <dbReference type="HOGENOM" id="CLU_1069655_0_0_1"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="16"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="260" mass="29729" checksum="FBB9000FD5F77FEE" modified="2013-05-29" version="1">MSVPFEVPAVFLDPDADLTLKSSDGVIFKIFKGILVFGSQFFRDMFKHAHPGHGNDDEPVKWDEPADLIVLLLYQLYPMPKPTLIDLDQVSRVLIVAEKWGMASATECVKVELLNFLDQRPIQVIKLASRLELKDIHEKAIHEFVKQHDPMDKRFRADLEDIDVTELARWYDLRQSCIQEFKGAMSANLFCNSPSVSSLMKDITRHLEGALSSSLIVNVFGTQYMDMVWNSGSKYCDCWHCSQKTIGERLTKFKREVDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8B6</accession>
    <name>M5G8B6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_14105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631898.1">
        <property type="nucleotide sequence ID" value="XM_040771015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8B6"/>
    <dbReference type="STRING" id="1858805.M5G8B6"/>
    <dbReference type="GeneID" id="63686077"/>
    <dbReference type="HOGENOM" id="CLU_990515_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052751">
        <property type="entry name" value="Plant_MAPKKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011:SF84">
        <property type="entry name" value="KINASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="281" mass="31339" checksum="EE482F1A36753553" modified="2013-05-29" version="1">MSISSWSSAGSTPSLCRSGTDMGDQGAPTVSLAEHVARLGVNLAEWLGRGGQAKVYAVKGGKDVLKVSKSKEYSPEAMSPRYLCNARLYIQLYRMVYNLKDDRIEEIYQILDVLHGLCHIHAHRFEHCDIKGENILVNHRGEAVISDLDSLATAMVERSWVPRTPYWRPPELWSSPDGGPKPGAVGTGDIWSLGCTIIELYTGRMPFHHVEYKKLLQYLLESGYRTCPELARKRGLDPALWALVLDMLDLDPSKRPTAHQALARLDNLIDTESNAWLPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8L0</accession>
    <name>M5G8L0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631978.1">
        <property type="nucleotide sequence ID" value="XM_040772013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8L0"/>
    <dbReference type="GeneID" id="63687075"/>
    <dbReference type="HOGENOM" id="CLU_1532499_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="175" mass="19804" checksum="1633903F36B9D567" modified="2013-05-29" version="1">MPKNDALLGTMRAFLLPAQLASSNMLHDLHKCVYERFVYESEDHPQQPDGKPFPSSPDELGQRCGVQQEREDLQSAIRRADRMTEDDEREFGVVRTLRQVGRATKMVYVVVHQNAKHGREDQVQPHRDPGREPKVELADAVVARSDRGHEHRHDLGVDETQTKIGVPGIEGGDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8M6</accession>
    <name>M5G8M6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_17156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627020.1">
        <property type="nucleotide sequence ID" value="XM_040771262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8M6"/>
    <dbReference type="STRING" id="1858805.M5G8M6"/>
    <dbReference type="GeneID" id="63686324"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_10_1"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="58"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="415" mass="46582" checksum="ECB5C9DC0E53279A" modified="2013-05-29" version="1">MQSNSAFLLLHGDSLTLPNDQTFRVSYKVPLPLRPESLRGLLSGGQTGSAAIGNGRYLVNSTELGNGTFGSVHLAVDMIKGRQVACKIIPLKSKDDSSDIERSGKYAAVMREVDILKKLSHPNINEVLDVCETSARTKICVVLGLSTGGDLFSHLVRRTRLNEMEAKYFLLQIFYGIKYLHQKGVAHRDLKPENILLVTPPPFPRLQIADFGLARMFPRDTQAKMNNRSLTVLGTVDYIAPEIAELMQIGQEKLITPTRGDVIAMAGDSWAIGCIAYQMFTGFQPFYPYEYMDSRDHDEDYHEVIPPAQPFDVPPAPETIEDDRMMPLPPLSGAAVKSKDGTRDELVRKAIMECKPDMSHDIWDSVPNARTMIEKLLDKLPQCRWTAKRALECGWMKADRKAMDEMYEKTIDMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Z7</accession>
    <name>M5G8Z7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_22020</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629241.1">
        <property type="nucleotide sequence ID" value="XM_040772643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8Z7"/>
    <dbReference type="STRING" id="1858805.M5G8Z7"/>
    <dbReference type="GeneID" id="63687705"/>
    <dbReference type="HOGENOM" id="CLU_062828_3_1_1"/>
    <dbReference type="OMA" id="YWARRTA"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="25"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU02347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="15324" checksum="D09B8610A670C651" modified="2013-05-29" version="1">MSSAAGGKSGGKAGGKAGGKAGASTADAKNLSRSSKAGLQFPVGRIHRLLKRGNYAQRIGAGAPVYLAAVLEYLAAELLELAGNAARDNKKARIVPRHLQLAIRNDEELTKLLGHVIVADGGVVPHIMPELLPTKTKSKKGAEPSQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G930</accession>
    <name>M5G930_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_54392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627190.1">
        <property type="nucleotide sequence ID" value="XM_040775249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G930"/>
    <dbReference type="STRING" id="1858805.M5G930"/>
    <dbReference type="GeneID" id="63690311"/>
    <dbReference type="HOGENOM" id="CLU_1959514_0_0_1"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU00293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="128" mass="14051" checksum="71457A71799EFC78" modified="2013-05-29" version="1">MRLLEREKDKEKDKGKGGAVPASSGSSTSIPVKKSWASPESREGKELQPSTFEPGDGSASEDNKPSTKKARKLWTKEETQMLIDGCEAHGVGNWTTILNDPSYSFQSRSATDLKDRYVLMLSDLSESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G957</accession>
    <name>M5G957_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UFD1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_46014</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040774679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G957"/>
    <dbReference type="STRING" id="1858805.M5G957"/>
    <dbReference type="GeneID" id="63689741"/>
    <dbReference type="HOGENOM" id="CLU_037790_1_1_1"/>
    <dbReference type="OMA" id="VCMIETD"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="9"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="109"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU05284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="378" mass="40934" checksum="6FE26BEAB4C512EA" modified="2013-05-29" version="1">MPRPPARAFDEYFRAYSVAMLNQKERANVSYGGKIIMPPSALASLTRLDIEAPWMFQLRNPSNSAATTHSGVLEFIADEGCVYLPYWMMKTLRLAEGDAIRITGAVLPKGTLVKLQAQTVDFLDVSEPKAVLEQSFRNYSALTMGDIIEIAYNGLTFELLVMEVQPLGQAINIIDVDLSVEFAPPKGYVEPERPAPKPVPTMASKLGIDTGKQETVAEAAGFEAFKGVGQALNGRRTKGKGKSGRKIQEVDEFSRIIRTDKPKLMTSDTVDAERKVPAALNLPFGKLFFGFPVTPLRPVAESTQTAPAAAEQEQTFQGQGQTLSGRRPRGDRPPLAPAGTAAAGAGGAGQGEKKPEEGEKWKGKGRSLTGKREVIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G962</accession>
    <name>M5G962_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">DACRYDRAFT_109065</name>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627225.1">
        <property type="nucleotide sequence ID" value="XM_040768801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G962"/>
    <dbReference type="GeneID" id="63683863"/>
    <dbReference type="HOGENOM" id="CLU_1758747_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="15012" checksum="FAB0B15DF975F66D" modified="2013-05-29" version="1">MLLDNAILPWKGAEGTDTISIPITTNTTPDVPPPTLSAPPSSPPPAPPSSPPPPSSPPPHASTPMAKIEDPASSATPPLLVVSLASSNGLLNTKHMNAKHANVSKPKRALLSPSLSASPPSPSPLPFLLPTQPPAWGIGFLVVNAAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G991</accession>
    <name>M5G991_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_29558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632233.1">
        <property type="nucleotide sequence ID" value="XM_040774316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G991"/>
    <dbReference type="STRING" id="1858805.M5G991"/>
    <dbReference type="GeneID" id="63689378"/>
    <dbReference type="HOGENOM" id="CLU_063278_0_0_1"/>
    <dbReference type="OMA" id="SQCFNIN"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33698" checksum="5047734840CD5232" modified="2013-05-29" version="1" fragment="single">GWAPLDLSEDAPPIGGVSVHDFVQAYSGLFEASASFFNSPLSYKEQFIRGTEGSEDGYNRVTGEKEMITIRTADTTPEDLRQRAAICWELCGRIMLDVIQDISSSLCLENDDLRDMVAPCATLPPSGQRVATLLRMFRYERGAGTPLGNEPGLRDRRIVAERHRDLGLLSLVVGSSHGLEVWDPYANAWYAIEEHQAAPGRLTATILAGETLARLTNHKYNPGGHRVVVSNLDDSPYRFSLVYALRAHHPVQVDTDRLTTSITGTFTRPLAALTAGELYSQISNAHFNINADMAQRRKQEERLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9P5</accession>
    <name>M5G9P5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_80747</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627440.1">
        <property type="nucleotide sequence ID" value="XM_040776468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9P5"/>
    <dbReference type="STRING" id="1858805.M5G9P5"/>
    <dbReference type="GeneID" id="63691530"/>
    <dbReference type="HOGENOM" id="CLU_063262_0_0_1"/>
    <dbReference type="OrthoDB" id="5325112at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="71"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU00543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="45461" checksum="C8F78678959CC23B" modified="2013-05-29" version="1" fragment="single">MDKSQVPPFQLQPLVTFQQQEDIINLSDSPAPSLRSSTNAPQNALRAFISGSGSARGLANLTGAAPAVQEKVEIRCAEAFESNLYIGCSDGTLLWYTLNESDSAANPYILQEKHTLPSRKAVSRIALIPRLSKALVLSDGTLYFFLLPSLEPIPISLINHIRGVLTFALDDADVFAHPEDVDATGLCVLTRRGVGLWSLRERLLPIKEVPLPYRGLIAKRYAEHMFIASEELYHFVDLSSSQSTEFAPIPTNQYSAGGVVVPPRPSIITVAQHEFLIALDGGAGAMGLFLKNGDPVRGTLEWEHLPRALAVDWPYVSALLPNGTVVVHSIETLKVVQTVDVPVSLGARTMSSSMDGLYAPSTANNRNLELVTMQIIPPFPETPPEEPEPEEEDSAAPQSGSGLTPPPSPPPKPAGKAAPPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9V7</accession>
    <name>M5G9V7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Taurine catabolism dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_20034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632493.1">
        <property type="nucleotide sequence ID" value="XM_040771769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9V7"/>
    <dbReference type="STRING" id="1858805.M5G9V7"/>
    <dbReference type="GeneID" id="63686831"/>
    <dbReference type="HOGENOM" id="CLU_036005_1_0_1"/>
    <dbReference type="OMA" id="HYQPAFN"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="322" mass="35545" checksum="DE8379E6B9D9AFE1" modified="2013-05-29" version="1">MLASLRIPVLHGVRGMATSASLQGSLAALVSHDLTPHIGTRFPDPLVQLSKILADARSSEMVKDLATLVSHRGVVFFTKQDLDIQQQKQLVLKMGELTGRPETSGLHKHPVSEDSSELGADVSVISSIGGIARAGVDLTGRASNGWHSDISFENVPADFSVLKMHTLPAVGGDTLWASGYEAYDRLSPAYKKFLEGLTAVHDGNFFHETARAQNVPIQSLRGSPLNDGEDLRAVHPVVRTHPITGFKALFVNRSFTTRILELTKEESDHQLDYLFRHIAENHDLQGRYRWEKDDLAIWDNRVVLHTATNVYADVRPNAVYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Y7</accession>
    <name>M5G9Y7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_20063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632528.1">
        <property type="nucleotide sequence ID" value="XM_040771778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Y7"/>
    <dbReference type="STRING" id="1858805.M5G9Y7"/>
    <dbReference type="GeneID" id="63686840"/>
    <dbReference type="HOGENOM" id="CLU_090389_11_0_1"/>
    <dbReference type="OMA" id="WRESGRI"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="25"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="145" mass="16170" checksum="E112063D9A838E02" modified="2013-05-29" version="1">MSIFAASRRLPTALSSSRLATRSFASTSRKLERFENADVNVFKKRVMDEGSSKLMIVDFYAAWCGPCRMLSPLLEKLTTDTTLTNGKEVDLMTVDVDKQTQLAGMFQVTSLPTVIIFKDKKAVQRFVGFIPMPKLQQIVAEAADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA74</accession>
    <name>M5GA74_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_113402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632119.1">
        <property type="nucleotide sequence ID" value="XM_040769624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA74"/>
    <dbReference type="STRING" id="1858805.M5GA74"/>
    <dbReference type="GeneID" id="63684686"/>
    <dbReference type="HOGENOM" id="CLU_061199_2_1_1"/>
    <dbReference type="OMA" id="REDSYCK"/>
    <dbReference type="OrthoDB" id="3348095at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="232" mass="25788" checksum="492F4EF2A62075E3" modified="2013-05-29" version="1">MQAALSILGFAPCHHMASLFETPARSVAFLDALNGKATDFRALMAGFRATVDNPGCDLVPELMAAFPKAKVVLGLRDSPEVWWKSCSETVYCMSYTSYQALVYPIPFLGLQSRVVTAILENKWLARYGVLSGPEVYTRHRAFIRDIVPPDQLLEFNVKEGWEPLCKFLGVPVPDVPFPHTNDSAEVNANIRMAKLMGVAAWTGILAVLGGAFYWGVREEVWKTTFGFLRKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAB7</accession>
    <name>M5GAB7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RabGAP/TBC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632658.1">
        <property type="nucleotide sequence ID" value="XM_040771817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAB7"/>
    <dbReference type="STRING" id="1858805.M5GAB7"/>
    <dbReference type="GeneID" id="63686879"/>
    <dbReference type="HOGENOM" id="CLU_004457_0_1_1"/>
    <dbReference type="OMA" id="WWREQRG"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000077">
        <property type="entry name" value="TBC1 domain family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="451"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU05764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="795" mass="90588" checksum="7C5D31DDFEBBD245" modified="2013-05-29" version="1">MGGGPAPFSRSQSSLSMKSTGSMVEITRDLENTNLENTPVLTVPEPQKEDEKFRLLYARSKVYIYPTAYARDNVPGWVALVKQEAPQPVYLLSWLPESLLQRKGHEELEKYVHVEAEEYDEQDGVLISPPVPRGELYAFSVPLSMIYSIIMSAPTLSAWYGTMTLNLISGSTLPKLYFHDDESRSLHERPREGSLTPKWGGEALLHRLRSYCTVLKSSLQSGLYLIDPSLSDKEAHSTILFDDGAVDDIMNPVPKHRRPSKPSKSGQSQSAPPSQRNSILHEGLSGSSSSNSTFERGVLTAFSHITQQARHAAQTILSHPLAQPIVPHLPEPVKSLVHADGEWSGWVEKGGVGEYESARVYLARWARIVAEAGERARQQESPADPDSSLLHVSSDLGVFEVLATSNNLPPPKPTRNPKAPIQEHEWDAWFSSTGRPTVEWSFVRTEIFRRGLTPEVRPKAWPFLLGVFSWTTDAIERATLFAKQKAQYNQIKSLWKDNEEVLQREDVVEERHRIDVDCRRTDRTHPYFAMPEEWTGSMSEFPQSPVGQSPANEHVQNLMSVLTTYNFYEKELGYVQGMSDLCSPLYVVFEGDESMTFWCFTRFMERMKPNFLRDQSGMKKQLLTLQQLIAVMDPELYRHFEKTESLNLFFCFRWILIIFKREFSFDEVMSLWEILWTDCYSTQFVLFVALAVLESHRNVILRYLVEFDEILKYCNDLSMTIDLDSTLAQAEVLFLSFQQRVAAIEARRKEQDASVDAVEGIRKRRGSKAPEDKLDAVELPVLSENLMELLENERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAS1</accession>
    <name>M5GAS1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair protein RAD14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_80488</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627925.1">
        <property type="nucleotide sequence ID" value="XM_040776449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAS1"/>
    <dbReference type="STRING" id="1858805.M5GAS1"/>
    <dbReference type="GeneID" id="63691511"/>
    <dbReference type="HOGENOM" id="CLU_053731_0_0_1"/>
    <dbReference type="OMA" id="EFGEDTY"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21077">
        <property type="entry name" value="DBD_Rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.530.10:FF:000003">
        <property type="entry name" value="Dna repair rad14 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022656">
        <property type="entry name" value="XPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022658">
        <property type="entry name" value="XPA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00598">
        <property type="entry name" value="rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05181">
        <property type="entry name" value="XPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00753">
        <property type="entry name" value="XPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="XPA C-terminal" evidence="12">
        <location>
            <begin position="206"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU01028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="338" mass="38783" checksum="1C126A8F3F5B3CC6" modified="2013-05-29" version="1">MSRPSTPPPRVAAPAAVPITPPPRPGVTERNVALTPEQVKQVEINRLKAKARLKKSERQRSEAGPSTTPNSNNKRPLTVTPWNSTSPTVPSKFQGPSTSKPEAPLPRDSWLGTYYEYDLSKMVNTKGGFLTEAEKGEAEKAQETRRKELERERERMKQNFDPPVFMNASKNPRCEQCGTIDIDHQYNKVYGVRVCAQCKDKFPELYSLLTKTECKADYLLTDSELRDETAMPHLLKANPHSATYNNMMLFLRKQVEAFAWEKWGGPKGLDAEWARREEGKKAKRGKKFEEKLRELRRRTRGNVWQKRKDQEHKHVFGLVVEGEQRCEECGFKVEVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAY4</accession>
    <name>M5GAY4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_22885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628000.1">
        <property type="nucleotide sequence ID" value="XM_040772999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAY4"/>
    <dbReference type="GeneID" id="63688061"/>
    <dbReference type="HOGENOM" id="CLU_786555_0_0_1"/>
    <dbReference type="OrthoDB" id="3380644at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU01103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="38837" checksum="CFD9A1F1C48FBF81" modified="2013-05-29" version="1">MDELTEMTTYTTAGAVVGQWLLGITTMDTIMLVFILSYVRGASAQGSRRLFGWLPPELLGQAGIAIGLTFFDYLYFVFRDMRFVSGVVWNAQTNVTLAMYYIDATNWRFTASVVVWLCKTAFADCVMLLRAIKLFHNNERLGGQFGYYSVLALLSLLYLGTVASGVVTWVGLLRPEAATFDTLLEKSATFFMSIHCGYNTLVTLLISFVYWRAMSHEFKMMTVAQLALRSFSAGNMMYTLLITVLVVLYQRQILFVYFWYDITQPLMTMSFTVPMLLTAFARILPAVGTMKSTNMTPVRGPGSGISVAVRREEILEDNYTTDSMPMHSLSPGEGDKQKAFESDEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB07</accession>
    <name>M5GB07_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Golgi-body localization protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_97695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632988.1">
        <property type="nucleotide sequence ID" value="XM_040777476.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GB07"/>
    <dbReference type="GeneID" id="63692538"/>
    <dbReference type="HOGENOM" id="CLU_000202_1_0_1"/>
    <dbReference type="OMA" id="FAHFWSW"/>
    <dbReference type="OrthoDB" id="1562405at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019441">
        <property type="entry name" value="FMP27/BLTP2/Hobbit_GFWDK_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019415">
        <property type="entry name" value="FMP27_SW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019449">
        <property type="entry name" value="FMP27_WPPW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01214">
        <property type="entry name" value="Fmp27_GFWDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01215">
        <property type="entry name" value="Fmp27_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01216">
        <property type="entry name" value="Fmp27_WPPW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMP27 SW motif-containing RBG unit" evidence="4">
        <location>
            <begin position="1311"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit" evidence="3">
        <location>
            <begin position="1431"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 WPPW motif-containing RBG unit" evidence="5">
        <location>
            <begin position="1844"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2675"/>
            <end position="2772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2862"/>
            <end position="3030"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2016"/>
            <end position="2043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2685"/>
            <end position="2697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2712"/>
            <end position="2722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2756"/>
            <end position="2765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2865"/>
            <end position="2874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2879"/>
            <end position="2891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2895"/>
            <end position="2912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2931"/>
            <end position="2947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2966"/>
            <end position="2977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3019"/>
            <end position="3030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3030" mass="339941" checksum="A9AC60E7B5DD6974" modified="2013-05-29" version="1">MSTVITAGIVILITTLLILVVRYGSPIILRGIFPQLQVSSVSPRSVRGLRWDGGAFRLSVERIGFGLHRPSAERTSWISIQVEKFDLQVLKRRRTLNRSKPNIPRFLTEAVPTEHPEFQNIADKEQVSAPVSLVKLLDADEEYAPPLAILSWVLPISYIQSIDRFLRPFFRVLLTQTLRTLFRALPSVTQLVQFEMDLCTITIEELNGAGVTISDVKVNTLVELQQMEDVPIDDLECDQGSAAAASGASRLTARMQSGMARLWNRAWGNAKGLARLKVSVRNVKAFCGDSEESSVERSSSLTPIPTATPTPFTSTTQSFSDMSTSTATGFFPKPVSSPSSPSSASIPPTPRNGPAIANTPLCLLFPPNLLFITHEEATVVMSMTLEPRRGIIGEGSISIDVNVPPAYMSVGALRRVGNALKKDSDEIGQQRDDTFSPALSPELSPTDSEDGQMPNWSTGFRTPITPGGSISRRLRSLAQSARKRAKVTKPKARPIAWRISQLLDYVHVHLQTVDMAFDLEDSTHGDNMTMSLKISELQTHLEMSDPTRSDHREWLGKKGNRGDGSDFSAFAFSVNAESFAVDRVSTFGILDGPTSLIDIRGVAFDLLTTAVPGQRAEESLFAQDENASFVICTTVVESVNVYDELDTLQRTMRLLNPAKPPRPLSPRSDLHNLPCVVLGLEVRTFGVHLGISPHEEGNDLDRRLFISLRNSGLSFNAQSAYVDLCTRAGLYQPGKAYCGEDPRRLDREELYSLRYDFTVDSAIAPFTVQLCHSKTDNVKEPLQIEGEIFSIGAFELGVVGHTLGSTSLAPSKYTSSLDISSTMSDIRIAVDYIAIDIWKPSVVDALRGAMDRHRPTPSTIPRLSGGSLLDKLPIGVCFYSSIGYITVLVAGEDPTISENINISRGVILRSGLVLQYCFYQTLRHTTRTKKQLGLTHSRQQLSLQEDLAAQAAAVANDVNYPDEFAALSGISLWDTSLRPVVNAEKDSPLYRTSKVPANAYPKLKDAVICSSPRLTIRVLLRKQRTTSSATHPHDESCDVMVEGPMLSIHAKLLHVFCLLLAWKNVPVRRHNRPEKEPKARRMASGKLEISFRANIEVVDMACHLHSKDRLYFRLGRLASEWKEGITAVRWASLYAWVPSPELEGKWEEFLRLRDWNLSITAASQSRPRMFDVSGKGARIHIPYRYVVYELTQGITISIKAIGHLLRCMRAGTFHEPPIPTAKAPRQVPDIRIHIDTLTMEAVDAPFESRLNLIWRTGHKEQLARMERELAFEAKVQAVNGFFEERPGSRASTAASTVGYTFSGQHSVSVEEAYNRLLLYNSQAWIKRHKYTKAERDRKEDGVYKSIHGTPYHFGPFSLPISVHTPDKAAPLLRIIFNGLDLSLAKPSFPLEQLPQFLQDVGRGIPLDTEYTLLIPMSVRWDMEDARITLRDYPLPLFHVPSKGNKGEPRWSLTSNFVIAEQVGPPSCITFIKTEVVPADTGLDGTPGLWFSMPKTCMPIKTLAEPQVYIRTSAVTEFAWGVSYNPAIHDVMRMLDSITSPPKDPSPTLGFWDKLRLVFHWRIKLDFARSGVHFHIKGSRDPYHVSDVGAGFALCWQGSPSISIGYSEQDQELIQVSSDRMSLVIPNLTHLDIQDQPPPETPNMPMSEDHPKRFRKVCAKFTNGVRWGIGFKLERTCRTEECDKCKGSIFHRQCRFFYFRPHWTVHLRAPPQGEKPEGGWPDSYAGFRSDFIHMGLSITSPTRNATMQGTSARTNGAGLSGYNSAHLTPKGFAHFFSWWRLFDGTMSVPIRQGKLFPSIKPPSKKFGKHLATIKYRVSLSPLVISHNYRQDSRSQWVRGETGAVGIKAMVEQFQADLHQRLQEVVIFHEKLQTTKRRVRKRFCAADVTLTNVEMRTMAAVFSEPEKTTVVDGIDDDDSAEAESHFSFVCDEVEPGWFDLDDFVDVDWSPSDHKPKIRLLRIGTCPRFSFSKRANARRLNRRSSDHSSNSGMEVTKFGDEDTHICLAGQADDAYQVQISLTSKRVAELESELEELLRTKRESKRVHQINDDSIDKPGSSLMDREADLLMKIRLLREYITRLKSAEQQAGADGGINHSFFEQGAFVPSNSDTNNGASTSQDWKNFDNVYEAHFPTIFLNNDTRNVLISDIPLESPALDEDLQVLLDYYYSSRAHRGLEYHMTERAIKFIRDHAKPVNDIPPEADEFRASSQPALGTSSQTGRVQGAAQGLFRLFTHDGRASDDSPRWRPHHTDDIFEDPHTGWLDDVLIRKSHIARLIKPQVVLRSDLNADSITVVAIRSVYIRNFTVLDREHLDDPINGPIMQRNYFSLSGLQAFYPARDQVLATSHVFVPLEVLLDLRSETRDFERLVPYTDAKLHYDKFNQLRLRKNMRTASVDNLSRRNEHLKLNMDRLVIGIPSFSVSADARNFTAVYNVATDLLLYRDPAQKARSQKLKTFLYSYDFTDLDSAADVVSGLQRRMRYLAEVENANILKPPHEGAMQEQLAIRAEMQNLAEELSFIFEAIKLKQDKAGGRTVEGDSSAVRVETYVSDISWMMLDPRHALLAKLSVKGIVFSWLNRKDGSADSTLELDDLLALNSTPEALFPEILCKYERPATHPMVRSGKFVRASWSTLAPVSGISIIRSFELHFHPIRLQIERKVGRQIMDYIFARSARRKEIEGPDRPVARSNGSGTSASTPRSSVFPLSKRHSSGPQEVERSTDEVGKLQKPRVILNRPSSFQDVTRAGSGPHPKSLKHVSSSEALLSASSPTENRDALEMRTRAAQNRTFLEINVASSVLVLSYKSEKTKSITDLYDFRFQVPSFQYHNQTWSFEDVVQQLRRDVIKAAWQQKGALFKEVVTKSRRPQHLLQQSRQNSEASRKSQSSIDSHQSIDSLNGKKSRASKLWHALQKRGKGKASGQPEPRLPSSLPPTLPASSRSSSLSIIQSASTNSDNEGRREHQNDGGTIERWIEDDKEEHFRSVSPDPLGSDTSSPSVTFPEEEEEVDEFDRRISLDMPQGRRPSVRRRTVSNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB39</accession>
    <name>M5GB39_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_98274</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632504.1">
        <property type="nucleotide sequence ID" value="XM_040777518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB39"/>
    <dbReference type="STRING" id="1858805.M5GB39"/>
    <dbReference type="GeneID" id="63692580"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="PLIKVYM"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="282" mass="31106" checksum="9D1B223EE751CF99" modified="2013-05-29" version="1">MGDWFKGELIGTGSFGPVYLGIDANTGTLMAVKQVELPTGSTSNEERTKSMISALEREVEVLKTLQHVNIVQYLGKAFACLHCSASDEKFFNVFLEYVPGGSIAKLLHNYGAFEEPLVRNFIGQVLTGLDYLHERGILHCNIRGSNILVGNDGVVKISDFYASKQVKENNGGERTAPRPSFQGSVFWMAPEVAMQKAGAYNCKADIWSIGCLVLEMLTGQHPWAELDQMQAMWKIGSKDKPTFPTDISTNAVDFLNKTLDPDPDNRPSAKELLQHPFTSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBV8</accession>
    <name>M5GBV8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_21108</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FIS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630451.1">
        <property type="nucleotide sequence ID" value="XM_040772236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBV8"/>
    <dbReference type="STRING" id="1858805.M5GBV8"/>
    <dbReference type="GeneID" id="63687298"/>
    <dbReference type="HOGENOM" id="CLU_104368_2_0_1"/>
    <dbReference type="OMA" id="QFNYAWG"/>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU03557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="155" mass="17549" checksum="8735BA2B508D5FA1" modified="2013-05-29" version="1" fragment="single">MPTDLPYAADAEISLSWDELDVLRQQYNNELEKSHVTVQTKFNYAWGLVKSPQREHQVEGVKLLQEIYRAEAGRRRECLYYLALGHYKMGNFDDARKFNELLLQKEPGNLQAQSLRDLIDRGVAREGYIGMAIAGGVAAVGTLLAVGLVRRAIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>M5GC04</accession>
    <name>M5GC04_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_21143</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630506.1">
        <property type="nucleotide sequence ID" value="XM_040772254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GC04"/>
    <dbReference type="STRING" id="1858805.M5GC04"/>
    <dbReference type="GeneID" id="63687316"/>
    <dbReference type="HOGENOM" id="CLU_007340_4_0_1"/>
    <dbReference type="OMA" id="ITERMWF"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="800" mass="88757" checksum="D9283AC96B9AFF18" modified="2013-05-29" version="1">MTTHPLFPRSPIKTLTTNGHAAVEKARRRPALSCAECRRLKLKCDRVWPCGQCKKRGCAQICPDGHLVPGKGNRFILANTEELHDRIDALEEALQKTVPGHPLLKASLYPYRTSPVETSPHASSAGNSSGTAGSSSPGSMHSHPEDLIDNIGTLAVGDDGHYKYFGNGAGSEFFAPEEAGSPFSPSSLPSPVSTSLSLFAGTGPTQSKQQLCAYLPPVDEARALCNNFFQHAAWLYDVVNQQQFENEIFVPTFYGNTTPSAHRLSLLFMILAVGALFDLSRPLHNPQADQFYEVAQECLRCDGGAYSNTTLPAIQAVQLMTHYVSNSPRKTDAETGWAQLGVLIKLAQSMGLHRDAARWDFPPEELEMRRKVFWEIHTHEVYTALCFGRPYSMHRSHIDCALPNDPTARMNPDGSVGFGFHTIKYFLCDKVMRIIDEVFCVTPPSYDTILALDRDIRDFQKTLVPEYLREPEDGHHPVDEDVTTLLQRQVITCFLNEALLYLHRGCFTRAIVENPSDPTATRFSPSFVATHRSSCTIIRAVLDLALLQPALVKRLSVYWFHAFSAAVVLATICIRSPRCALAPSAFRDLTAACDFFAAAEPQSRVAQGLPLLQRLHAKAVRAMAEAGFMADPGLVQDMSSDDEQELNTPGPTIKKESPDECALLGYRTRLDRTSPPRSRDGPLRLNGNPLVNIDALDWSSIVQPPQPNPRPFTNAHPSLLEYLQSFNNMQSQPTAMSTFNQQTYNMEPYTTRSDLSVQQPYLDSYGQISPQQQSAFSFTPTPSVEVTSWENYITFGRQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCA9</accession>
    <name>M5GCA9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_105922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630661.1">
        <property type="nucleotide sequence ID" value="XM_040768167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCA9"/>
    <dbReference type="GeneID" id="63683229"/>
    <dbReference type="HOGENOM" id="CLU_162139_0_0_1"/>
    <dbReference type="OMA" id="IRAGQKW"/>
    <dbReference type="OrthoDB" id="3237970at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="113" mass="12872" checksum="F3E531E5BEF9F640" modified="2013-05-29" version="1">MVNGSISSHASRDFYLDVDVSEAIMRPTPASLARILPRSSVPRKLVRPELRPQPNKANAPTLISKLLEQKRETIRAGQKWPANLRIEEPLTRKDWVGVPRDLRAELKKLVKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCZ4</accession>
    <name>M5GCZ4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_48717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631036.1">
        <property type="nucleotide sequence ID" value="XM_040774862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCZ4"/>
    <dbReference type="GeneID" id="63689924"/>
    <dbReference type="HOGENOM" id="CLU_174933_0_0_1"/>
    <dbReference type="OMA" id="VCCMIDR"/>
    <dbReference type="OrthoDB" id="2564984at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019317">
        <property type="entry name" value="BRI3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10164">
        <property type="entry name" value="BRI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="9500" checksum="FAA7D896EC1EB2FD" modified="2013-05-29" version="1">MVGAPHLDAGRTVYYYTNPMNGATITSFLPPDHPRSLCLQQGHVPMTTHGVLGILAAIFFFPIGVVCCMIDRRSVCARCGEVLSDGCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD61</accession>
    <name>M5GD61_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629045.1">
        <property type="nucleotide sequence ID" value="XM_040772593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD61"/>
    <dbReference type="GeneID" id="63687655"/>
    <dbReference type="HOGENOM" id="CLU_2469034_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="88" mass="9964" checksum="0184E063BF5BCA08" modified="2013-05-29" version="1">MSLTPIPPLLLNKKLALHAKGLAQSRPLGYHRPVRGHTWILHLMLIEPRLVHNEEDRLTMSTTRLTYLSTIAHCAYNLTQTSSLPNPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDR6</accession>
    <name>M5GDR6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631651.1">
        <property type="nucleotide sequence ID" value="XM_040771919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDR6"/>
    <dbReference type="GeneID" id="63686981"/>
    <dbReference type="HOGENOM" id="CLU_2800898_0_0_1"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="68" mass="7408" checksum="EABD2B8CC276190C" modified="2013-05-29" version="1" fragment="single">MAAVLIRVATQDLWVANLGDCLVVKGHDRGGDPSGSWDVGRLTEEHNTHNANEVKRIQDAHPGESCIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEX6</accession>
    <name>M5GEX6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Surp module</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_98382</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632681.1">
        <property type="nucleotide sequence ID" value="XM_040777524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEX6"/>
    <dbReference type="STRING" id="1858805.M5GEX6"/>
    <dbReference type="GeneID" id="63692586"/>
    <dbReference type="HOGENOM" id="CLU_013259_1_0_1"/>
    <dbReference type="OMA" id="HAYYRHR"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000002">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="10">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="10">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="684"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="627"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="328"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="771" mass="85601" checksum="CC70079BF112AE1A" modified="2013-05-29" version="1">MADVAMQSAVSTAPNGINAHPNGHEHTNGTEEPKFATGMIYPSPEIRTIIDRTALHVARSQNPQQFEDRVRESQRTDPKFAFLAPTDAFHAYYRHRVERIRAGEDVNADTGAAVKTLPSENALEPELVKKPSGRPRAAPPEPPEMEFVAPTPKVPPLELDTVKLTALFFAVRGATFLQALSVREGQNPQFEFLRPNHPLFNYFSRLVSQYKAVLLPTREGRETLRLEAGSEGRTRLLEKAKARADWERWKREREKKRAEDQEAERKAFAEIDWHDYAIVQTIEFTVADAQAELPPPQSVQDVENMTLAQKRMTKLINESTTEEIKAANERDVREKAEAEELRVREEERLREEAQEMQVAGVKRKALEAENEQDVEVARLAQDEAERLRREAMAQAQAQLPGQMKIRENYVPKGIQRGAKKMTMCTICGQQVPIDELEEHMRIELLDPRWKSQRDTLEARRTQANELQFGANVASSLRTLARTRVDIFGAEEDEALRKSEEEAEKARAKEREKIVWDGHTASKESTAGKFQTNVNFEEQIAAIHRAKGLGVMADSGGPSIGPALGPGITPSSSAALAPTLPEYANAVISAAPQPATAPVYGGPGASSLQTSTFSPAAATAAGFVPPGMHPSRLAALSTPSGPTPEGSETPPEGQPPAKRQRVERYEGHTYAENDWISLHPEPISLQVQLPKLDRLPEYHFDGQVALIPDLPLTLLVSTLRDRILTQVDSACPVGRIRLTYGGKTLTNAQTIASYNLEEGDALYLTVRDVKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFA1</accession>
    <name>M5GFA1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_45356</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632981.1">
        <property type="nucleotide sequence ID" value="XM_040774638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFA1"/>
    <dbReference type="STRING" id="1858805.M5GFA1"/>
    <dbReference type="GeneID" id="63689700"/>
    <dbReference type="HOGENOM" id="CLU_009665_20_0_1"/>
    <dbReference type="OMA" id="VGCDGTR"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="48233" checksum="4F51644D1759EF6D" modified="2013-05-29" version="1">MTLPAEVDVLVVGAGPTGLTCASSILTHGVPVNRMAIVDAPDAGNMIYSRALVVHSKTLEAMEKIGCTEGVVAAGHPHQLFHFNSLSSPNGPLITLKASLLQPWTKYAFFLVIAQCDTERVLMGRLKELLGEEDIRWGKRVVDVRETEEGWKVASFEDGQQVRARYVVGADGGHSVVRQSAGIAFPDPYNHTAQSTPEPADIDHPSKADEVFCLADVRITSPISSGNVEEFNAYLTPSGVALWIPLGDGVYRMGGQVLSGSAPKEPDQAYLQQLLSERILIASGATITEVLWSSRFHIKFRLAERYWVEHLPGTAVQRDGKTGVILVGDAAHVHSPMGKCLGMNLGIRDSITLGQALSHALSPAVSPTEARTLLTRWARDRHTEGSHVIALSGRLTWVSIWGSALGAWTQKARDWLLWGVVRVPGVMRVMVWNLSGLGEKDTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFG7</accession>
    <name>M5GFG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_12987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633166.1">
        <property type="nucleotide sequence ID" value="XM_040770955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFG7"/>
    <dbReference type="GeneID" id="63686017"/>
    <dbReference type="HOGENOM" id="CLU_503447_0_0_1"/>
    <dbReference type="OrthoDB" id="3267789at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="541" mass="54724" checksum="CB3576B507DD56CC" modified="2013-05-29" version="1">MPPQLAISTAPSSLPSTNGSGAGRGKSYYRGRRGARGVNSASASDTGSATESSGPSLLSRIGPRTDGTVEAASPTTPRAEGRGKSALSIRGTGLPPKPVHGSGNATGNGKRGSGARKVPSSISLSASSVSSVEVIRDPPPHSVADPPPMLSSANSSKDRRVAQSAPPERPVFDNVESDRPASALVVSATKEASLRSVSPTPRLNWADETDDDSLPDLDDWMTPALTAGLGYKDETAPGEEDDHATPVATNAPAGPLRERRKRGAGKKNKQLAAKAAENAAAAAAAATSDATPGGTANAQDPPASGLDESITNLSLGVSGKEEENKGNKVKPKEKETEVTTPKADWRSVLPDTGRDGALQLLSALAGSISTSKPAYRTPAQRHAEAAVTVVSSATLDPPVISAPEPSKPATVSAGPSTRVRAVPSPAPIGGVSSRGGPQSFPSRVSPRVNGVHHSTVSGGGFRGPYRAEPGDTPVTLPKKHARPVITADAITRLARGLMATPKHDHSGAGNGGGSMNGSEGGSTAGDGDNDAKENKADSVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFK4</accession>
    <name>M5GFK4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_92417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633291.1">
        <property type="nucleotide sequence ID" value="XM_040777073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFK4"/>
    <dbReference type="STRING" id="1858805.M5GFK4"/>
    <dbReference type="GeneID" id="63692135"/>
    <dbReference type="HOGENOM" id="CLU_275833_0_0_1"/>
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    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000428">
        <property type="entry name" value="Related to WHI3-involved in regulation of cell size"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="928"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="255"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="786"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="799"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="842"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="875"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="886"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="916"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1063"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1156" mass="120215" checksum="A5F2B513D41B1AE9" modified="2013-05-29" version="1">MATYSGPQLALPPPHESYAAYRLNSLSYAPSALSPGSEPFDPVRGGPRFDQFDDEHMTQLPNTGAAFGNLAPGAPSVNQMLGRGSVQLHSGYTRPRAPQNATITTTYPDSMNRIGSVPNLMSPVGGPSEAFPGRQGPKDILSPQARAFELSGTGGAGALQQKLLLQQQSSNQQQQLEAQRALQMQNVQALQLERHRQQQQMVQQQAPAQGNQGGFGANGLSNANGQPINLGNISSMNGVVVPGVGAVKAASLPSSTPAFQQQSQRVQRGQDTSGNAPYANQQSLGNAPGSLHVPPGFTNSTTPQSSGAATGNTSGGGLSSAAAAPPLAAEEISTIFVVGFPDDMQEREFQNMFTFSPGFEAATLKIPNKDLTSYGPGALAPGSSAAAAVNVLRQAGFASSYAGGGAQAAGDPYSLVGLNAQGGLIDSREISSGLAAAAASGWQIPEDPFARNSASGLMGIGGNPTDLTSHLALPMPRKQIIGFAKFRTREQASEARDVLQGRRIDVEKGAVLKAEMAKKNLHTKRGVGPLGGSSAAGNAGANDPMSLASPPGMNGPNGAVGLPGYAGVQGSGLPPLGNTMSNDGSIPLTQRDKDMQTIVAMGLNPSSQRIMDTDRVKDRQQRLEMEGAYQQGLQGPTRSRMTAYDAFHSVADPEVQQHVPGRQPSIVGRGSISAGSGPGLVSRGMLSPTFESMSPSATDPYAPFGLLNGAGDHGLPGGISTRAGLPSSMLDRRMSHSHGQVQPSRQDPMAATQDMWESLPNTNASDPYNQGMLKGLSHMNIAEDPEEDAGAAPRSAAVPSSTSSNRSQPSPPADKDAVGHRSNGSPPGMIQGNRIDARPPGRESSPPRGMMSGQSMSSEGSPSREESRLGNIDSLIRRDSGDSDLTRSSMTGIHTNTHGEMTSPPLSSPGSGGSYIRTNSSDQNPPINTLYVGNLPTTPPASLSSNPLEENLKTVFSQCPGFRKLCFRQKSNGPMCFIEFDDVDYATKAMHSLYGHTLNGLVKGGIRLSFSKNPLGVRSGSVSAGSSSAHGHIGQESVGRYGRHGSLAELRGPSRQSSLDMLSPTGSSFSFGSSPPSRFFSPPPPGQMGSVSPPIGSGRNLPGGYFRSSQAFADTTFSPFAVPVASGNLLGPSFSEEGFEEFSYALAPSPDPEANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG81</accession>
    <name>M5GG81_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_114321</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631922.1">
        <property type="nucleotide sequence ID" value="XM_040769797.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GG81"/>
    <dbReference type="GeneID" id="63684859"/>
    <dbReference type="HOGENOM" id="CLU_008262_0_0_1"/>
    <dbReference type="OMA" id="KINDAEC"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022702">
        <property type="entry name" value="Cytosine_MeTrfase1_RFD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12047">
        <property type="entry name" value="DNMT1-RFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="498"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="684"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="86"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1321" mass="149074" checksum="A866615F7A5FF15A" modified="2013-05-29" version="1">MSSGLKRPYANDESDLDSESGTVFFGRKDGPTRNGKALRVSATNSRASSITAITSPITLKCAQLSTKDEFFTIPEDCLQEQDHLLPEESLPAKTTLPDESLRDDSSATSSVSDWSRENPPAQAHDRSQEKNLYDKESSEDPPNSESLPIRVLTDFILYDENNNNRIVSLEALYEPGTSLRAYGFVSSLPVDPENEEELEIADEDAESETSDENTYELNLSAIFSLQIDPNPTEPMFWLRTSFAWYILDRPDPRCLPVYVPYWKHLYLARLALSKTRTVTRRYKLTYDSIMQEELGGAVSLFSTSFTDEEIRGLDVCSESDFYDLINDVNDEDNEKTRTALELAYTELLLSRVKNPKQRKITKGLPKRTVARHVTRDGRHPELNLMGSRNTKKHVNIEFEVLKHRNPTYATPFVRSLASDLCFRLYGQSIKEEDGEESAINLTCDPETVLDGAFSFSSEPDTSLVWKLSDHRDEEYVNEEAVNSYLSAASGSATGRKGLSLRAGDLVVVRGDPRDEDPVGASKRLVGKGAANDWVYWFAQVIFFYKNPRDRESEAHVRWLAHSSRTQLGEAGHPRELVLRNLCSSINLSTILNKIKVQYIRPWEEEPSGFPYRAIDRDNFFYRYAANHEGDLLCASRFMFPTETEDTDSIHAYGCFTCHLRQSIEEDNIPRMPKPDSGLLLYKGVTYHLFDFVYFGWTDKNHVNKAYRIGQIVKINRQAINPSMTLTLFERYDEVVCAVGEEYRDHKRLVATQRKVSIYAERIRGKCYVMHRDAIRDFASWMLADDRFFVDHAAPISNGNATWSPTALTPLPLSDVRYCHDVDCNIQRISKQNPRPTRKLRALDLYHGAGGLSHGLEKSGAFETCWGVDLSPSAHMTFKKNFPNAIAIFQCANEVLRHAIENAQGADHDSLYPIGGGDVACPPLPNPGDPDIIICGPPCQGYSVLNSYRRTDDIKNTLVANALSYVDYFRPRFFLLENVQPLLNSRGKVLKPGDIDERIIENAVRKFIVRFLTARGYQVRVTVLQAGEFGVAQHRARVFFWAAKRNEALPEFPLPTHTWARTTPSRRDALGGAPLPCVTVKDVIGDLPEWHWINPKKLMPRPVVPKPAGPHFDAVTYDRKTRTCGYAGFVPYATLPATAYQKELRGNRKGVRYHSTLTYVGESVERVCNVPRPKGDKCLDAGRDYRELDGRFSVWHLTCPHSRAARGGYGEGKYARVYPDRPARTVLTRNEPTGKQGRVLHYNQNRVLSAQENARLQGFADTFTFISGTDDLRDIMRLIGNAVPIPLGYHLGRQLASAALAKEAECAAELAIKGERSPSPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGD1</accession>
    <name>M5GGD1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CipC-like antibiotic response protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_45962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632172.1">
        <property type="nucleotide sequence ID" value="XM_040774674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGD1"/>
    <dbReference type="STRING" id="1858805.M5GGD1"/>
    <dbReference type="GeneID" id="63689736"/>
    <dbReference type="HOGENOM" id="CLU_1272721_0_0_1"/>
    <dbReference type="OMA" id="MHAYESH"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="21948" checksum="666F54D20C20B3D5" modified="2013-05-29" version="1">MQQAEQLHGQMYAYQGYVQPEHKASWTHEAIAAAAGFAAMKAWESHLRATGQQPTHETMKEILAAIAAAEVDRLAETKGLDFIDRERAKHQAVAQAHAFANERYRGGTGAEYAQQWGGPAQEYQWNGGYGQYQGWHQQYQQGPWGGYGGGGYGPPGGGYGPPGGGYGPPGGGYGPPGGGNGPPPGEWEGGERHHHHHHHRENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGJ6</accession>
    <name>M5GGJ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-methionine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_113675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632497.1">
        <property type="nucleotide sequence ID" value="XM_040769677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGJ6"/>
    <dbReference type="STRING" id="1858805.M5GGJ6"/>
    <dbReference type="GeneID" id="63684739"/>
    <dbReference type="HOGENOM" id="CLU_007946_3_6_1"/>
    <dbReference type="OMA" id="TYWVISF"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000042">
        <property type="entry name" value="Similar to amino acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="571" mass="61723" checksum="CACFF7950573D8A5" modified="2013-05-29" version="1">MSYQPLPSPAHGDHESTFASPRSSTESLRALEYSDGLQAIRPGRSRGYSISSVATFDFQNNLLPLSLTTELDDEKEVVGERTIGLFHAIALVVSLQIGSGIFSSPGVVFANVGSVGASMIVWLLSGILAWTGASSFAELGAMIPLNGGAQAYLAYAYNPVVSFMFSWTAIAVLKPGGNAIIALIFGEYMNRLFYGQTRPDSPPDAIPIWATKLTATVAVALVSLVCLINPKSGTGAALGFTLMKILALFAISIMGIVQLARGKASPSLLTDIFEGTSPNPSSWAIAAYSGLWAFDGWDQTNYVAGEMKHAERNLPRAIHISMFTVIILFLWANVSYFIVLDKVTVGRTNTIALDFGSVLFGRVGGIVFSIMVALSCFGALNGSFFTSARLIYVAGKEGHLPSLFGKLHRTRKTPVNAMILQAILTCGFILVGGGFRSLINFYSVAGWSFYGLTVMGLIVLRVKEPHLERPYKTWIITPLTFCAVALFLLSMPVIAAPLEALAAVGFILLGLPVYFITQRPNERIQEASSVLSRMKNMVASCLSCFSRGQSKERVRTATNTTEERVEMIERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH55</accession>
    <name>M5GH55_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633542.1">
        <property type="nucleotide sequence ID" value="XM_040771628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH55"/>
    <dbReference type="GeneID" id="63686690"/>
    <dbReference type="HOGENOM" id="CLU_1735780_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="151" mass="15976" checksum="0D0C41BDC8643DFC" modified="2013-05-29" version="1" fragment="single">MDAFKDLWDNAAPAAAAAQAAKSQSLNAAAAQASARSYNRPDTFALLSSAPGSRTLTPSLPAQRPTSAASVTRPASEPRNGDAFSNLMSFSSSAAASSNLSLSDRQAKMEAEKKERERQQHEEYKSQGAFWDKFGGDDLLQPTPVPAAPTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5GH58</accession>
    <name>M5GH58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_103609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633557.1">
        <property type="nucleotide sequence ID" value="XM_040767790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GH58"/>
    <dbReference type="STRING" id="1858805.M5GH58"/>
    <dbReference type="GeneID" id="63682852"/>
    <dbReference type="HOGENOM" id="CLU_2432825_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="91" mass="10423" checksum="36C1D8ABDE0B6701" modified="2013-05-29" version="1" fragment="single">MPIIEEISKGPEVGTIDAFDEAIELLSKDLPIPTEFMADDVPTDPEKVAKLKEWKNATEMHLYKLQEYLRTKPELELEQRTRVVISAGLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FND7</accession>
    <name>M5FND7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_18685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624163.1">
        <property type="nucleotide sequence ID" value="XM_040771376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FND7"/>
    <dbReference type="GeneID" id="63686438"/>
    <dbReference type="HOGENOM" id="CLU_801733_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="38802" checksum="D6D8959E4FAEB980" modified="2013-05-29" version="1">MTKTMTPKQNQSTNSKTPGGKAKNKEQEVPMSPSSAEDHVPTMKDTQCRRDVGSIMLNSDGSHRYKTVGARPLIHVKGAEWAWELNHWELCEKMANRHKPMVLFECQLDEGSKDSQGMGDEGKGIETGRFYYILQEMEIHSATYNEIAKLPEISKEMLRCAWNTCKIAKPGEESGNSPAPHELMVEIVGHFEEDNGTEESVDFSEVTNILSTDILELEFFVGSIFSTPMFFDAVLASVHNHMYPYSGTLREWDAPRNTELVTLFFFLDVDAEKVVHWIELHAQASTFIFDRVSVPGGPNHRTVPVTLKENASPSWSQTGVLGFQEPLAPGALERAVQAQLQKVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNP4</accession>
    <name>M5FNP4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_58346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624663.1">
        <property type="nucleotide sequence ID" value="XM_040775494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNP4"/>
    <dbReference type="STRING" id="1858805.M5FNP4"/>
    <dbReference type="GeneID" id="63690556"/>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OMA" id="THRNIRG"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="320" mass="33851" checksum="CCB02B5C456B518B" modified="2013-05-29" version="1">MSPVAVNKTRTLKAGVHVPVLTFFESTAAQDIDIPVYENHVRRMAAAGVESIVVLGSTGEAVTLSLEEKKQLISVTRKVLDGIGFEEMPVIAGLATQSTREAMASADAFAQAGADYLLALPPSYYAGAMTKAAIKGFYTDLADASPIPVIIYSYPGVSSGLELDSEDVLEISTHRNIRGIKQTDHNVGKMARIAAGSPDPSSFAVLGGASEYLIGSLAVGAIGCITGMANLTPVTCVRAYKAWQAGDYKEAQRLQGLIATGEWAFGKNSLPGVKAGMNQYVGYGGVCRKPVPEASADIKAWTNKQLEPLFAQERAFTTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNZ9</accession>
    <name>M5FNZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795881">
        <property type="protein sequence ID" value="EJT96673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623571.1">
        <property type="nucleotide sequence ID" value="XM_040769428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNZ9"/>
    <dbReference type="STRING" id="1858805.M5FNZ9"/>
    <dbReference type="GeneID" id="63684490"/>
    <dbReference type="HOGENOM" id="CLU_789934_0_0_1"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="39760" checksum="A068FB058C886FBB" modified="2013-05-29" version="1">MPTSSTDTDLTAVVGSPSPTAAAQGGQERKASSFGTSDTAADLETFTDAAFDVDRMKYERKKRKMCTEKRSVGRSSWLEEMPANIMLEVFSCVEPIDLFKLSYINKNTRAVLITAESKAIWAQARKNVPGLPGLPPDMTEWFYAALLFQQTCQMCGIDAMARSETPFIRMRLCSACTSKHLKLDKTAKEMGLFLTHLLNASAKQQTQKCNEFARRMKELGHDARDLERIDIKQFVREETWDQVLPRIGMIANANRDRRLREQFVARNQSKARAIFVQLYYALPTELEKNSFLPVKDFLTLRSVRSLLASRAPDDEFDTCARSALPHISAESNAFCARMRRDLKADDDAWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPA5</accession>
    <name>M5FPA5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623826.1">
        <property type="nucleotide sequence ID" value="XM_040767651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPA5"/>
    <dbReference type="STRING" id="1858805.M5FPA5"/>
    <dbReference type="GeneID" id="63682713"/>
    <dbReference type="HOGENOM" id="CLU_041942_1_0_1"/>
    <dbReference type="OrthoDB" id="2748701at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT96928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="358" mass="40477" checksum="533052A16E2EB3FF" modified="2013-05-29" version="1">MVPQLPVELHRRIYAMACTDDGTTACALSLVSHAVREVVEEFRWFSLAVAGERQVQTLLETLQDVPKDRLKVAHLFVSDLRRPLSYRRREKRMLSLLEREELSEEDETFLRTTMGSLDFSIGSKIVIHLGSIECIEPPSRTASQYIMWLLRLLAPDLITLSLVVFSDQDDAFESTPLRINPSRLTSFPPLVFCALTPAPSSGRRMSHFRSGTASSSKPSRTHPSPNFKTIKRLLVAMGLRPPTSMEEEAIRNNEMDLFPHGVERFCLVEPGPTNFTSRRNKGSSRGRVRSPGFVPRSYLNMVMELEDVADELPNFALLPKHSGHNKQIEAEKSRQQWMERIEGGQGCWVTPAEFIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPJ4</accession>
    <name>M5FPJ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-terminal Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_120076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795929">
        <property type="protein sequence ID" value="EJT96474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623372.1">
        <property type="nucleotide sequence ID" value="XM_040770934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPJ4"/>
    <dbReference type="STRING" id="1858805.M5FPJ4"/>
    <dbReference type="GeneID" id="63685996"/>
    <dbReference type="HOGENOM" id="CLU_659811_0_0_1"/>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="3">
        <location>
            <begin position="316"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT96474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="417" mass="45417" checksum="0B6BBD2D66EA0263" modified="2013-05-29" version="1" fragment="single">MECQQQPTAHALRIPSCQLSISTIASSQRNTMTPQQASPVRSTLLHSSPARNHVAASYRTASSSTISPSSTGAPTPVTAPPTSAHVPGLGEDCFLDLMGMPTPPPSVRARAGRVGYSDGRTASSAPPQGVAELVALSPRSRLDGRWEPIEPFSEDRSSLELDHAHILCLQQLAEGTLSVDGGPALRGSHSFDSVLTARVDPQSPDLEHTPTAITPPGAIHSPTLEITPPTKNSFIASYHALVFDVLQTFDGSALSSPSNRTSPVPFENGDAVNPLPPDDPRFILWSTPTPPVVPTGPPRQSAFINVQPPTPTQGPVRRNLLACTLERWIAQLTSSLDYDILLDTLISYRPFLPPAALARLLIMRFMWTLQQPPADYHPTEIKRQEVVRKIVRLRTMLVMRCWLQVFFRVDFVHNKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPK8</accession>
    <name>M5FPK8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_33239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625533.1">
        <property type="nucleotide sequence ID" value="XM_040774372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPK8"/>
    <dbReference type="STRING" id="1858805.M5FPK8"/>
    <dbReference type="GeneID" id="63689434"/>
    <dbReference type="HOGENOM" id="CLU_904774_0_0_1"/>
    <dbReference type="OMA" id="ERNTIWA"/>
    <dbReference type="OrthoDB" id="2587928at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Right handed beta helix" evidence="1">
        <location>
            <begin position="145"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="308" mass="32816" checksum="C321280F6101CF19" modified="2013-05-29" version="1" fragment="single">LSLCPGQTYKLDYPLNFTAQDQEILTLGFPTDHTRATLVVAGHLSGVNANHSTAINGQCRGCDRVKVRYIQVDGQRDPDADILPGGGANIALGGSNTGQLVEFTRSYDPRSWSCLHFHEGQHACSKATVVNNDIGPCGFSEYEEWADGISLSCKESYVAGNLIRDATDGGIVVFGAPGSLIERNTIWAVNRTLLGGINMVDYDPWEGDYSGTIVQHNLVVGGVPGRDPADPKELDAFVKVGIAVGSRIWFGDKYDSERYVAHGSVKNNVFTGAFGYAIAISGAKQFSVHANVLSGPTSFVGSPGPTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPT6</accession>
    <name>M5FPT6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_36572</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624201.1">
        <property type="nucleotide sequence ID" value="XM_040774412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPT6"/>
    <dbReference type="STRING" id="1858805.M5FPT6"/>
    <dbReference type="GeneID" id="63689474"/>
    <dbReference type="HOGENOM" id="CLU_015166_10_9_1"/>
    <dbReference type="OMA" id="YKMSVPK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="104"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="206"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJT97303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="298" mass="32386" checksum="E13827228BBDD6EC" modified="2013-05-29" version="1" fragment="single">EILTFFIAGGCAGAASRTVVSPLERLKILQQVQPHQSGRALAYTGVWSGLVKMWQEEGFKGFMRGNGVNCVRIVPYSAVQFTSYEQLKTASSRLWFTNNGQTKLDTPTRLCAGALAGITSVVTTYPLDLVRSRLSIVSASLDSHSHAKDKIPGIWGMTAKVYREEGGIRGLYKGLVPTAVGVAPYVGINFAAYELLRGIITPPEKQTTLRKLLCGALAGTISQTCTYPLDVLRRKMQVNGMKDNVLGVKYKSATGAVISIVRTEGVVGLYRGLWPNLLKVAPSIATSFFVYESVKEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPZ1</accession>
    <name>M5FPZ1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_111965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624326.1">
        <property type="nucleotide sequence ID" value="XM_040769318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPZ1"/>
    <dbReference type="STRING" id="1858805.M5FPZ1"/>
    <dbReference type="GeneID" id="63684380"/>
    <dbReference type="HOGENOM" id="CLU_010194_8_1_1"/>
    <dbReference type="OMA" id="FWKQIEV"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT97428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="35055" checksum="5B0FD5ADB5222470" modified="2013-05-29" version="1">MADLDIKAIHTNVYPSIDPSNFPNTLSGKIAFITGAGRGIGRAIAIAFAQAGVKGLALLARSTGELEETAELCKKEREVQVCICTADAAKTSELDAAVDKAVKELGEIDILVNNAGANRLRPFHMTPPDEWWSILEVNLHNPAHLMSRVINPMRARNSGQYIINISSRAAVMASRGFASSYTSSKTALTRMTACVQAELTMDNIDRVCCFSLHPGGPKTKMNYGLVEPDVDAAYPGMHERVRKFVDIQEDTVELCAWTVVYLCSGKADKLRGRYFDVEQDVGAVMQHEEEVLRDNRGDLKVDMAGDWTYLTSSTNQMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQ98</accession>
    <name>M5FQ98_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucocorticoid receptor-like (DNA-binding domain)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_24979</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624496.1">
        <property type="nucleotide sequence ID" value="XM_040773945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQ98"/>
    <dbReference type="STRING" id="1858805.M5FQ98"/>
    <dbReference type="GeneID" id="63689007"/>
    <dbReference type="HOGENOM" id="CLU_139869_2_1_1"/>
    <dbReference type="OMA" id="FGLCRNQ"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1480:FF:000001">
        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11464" checksum="A5BB90BA57436D5C" modified="2013-05-29" version="1">MPNIRVLRDNAVRKGVKAHEIVRRAYLYVARNQTLPSPLRYQAMLQLNNFGRYSRPTVVKSRCTVSGRGRGIINEFGLCRYQFRLKALKGELPGVSKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQZ9</accession>
    <name>M5FQZ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_18936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JH795878">
        <property type="protein sequence ID" value="EJT97239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624137.1">
        <property type="nucleotide sequence ID" value="XM_040771411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQZ9"/>
    <dbReference type="STRING" id="1858805.M5FQZ9"/>
    <dbReference type="GeneID" id="63686473"/>
    <dbReference type="HOGENOM" id="CLU_789933_0_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF10">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="6">
        <location>
            <begin position="254"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJT97239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="351" mass="38687" checksum="BBE5CE889D9FA36F" modified="2013-05-29" version="1">MAATWDLDLVGEVAAKILAPECKLKAASMLLGPTCNIQRVNRDLSRTLLRLMNREGISACIKHLVGNEQEQERRGSDSLNSDRPLQESYLYPFILAQKNSKPWSYMTASVISPPIVERSLISIVQRVAEFVKKVATSAPEILDGDQKERTYDTRADAALLRKVASNAIVLLKNNGAILPLKAENIKTLAIIGPSAKQMYCACGGSASLNASYVVTPTDGIVAALPKNVNVVYAEGCQGHKRAPILTDHELTTPKGTPGMKGTFYLKQTDNGQYSEPTDSFLLDNMNSKMHDSDIFFAKEEWYMVLEGRIRPVQEKTEFRLGPSVSGRARLFLDDTLLIDLWSWGPGTAQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR58</accession>
    <name>M5FR58_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_111078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624996.1">
        <property type="nucleotide sequence ID" value="XM_040769170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR58"/>
    <dbReference type="GeneID" id="63684232"/>
    <dbReference type="HOGENOM" id="CLU_2250045_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="104" mass="12042" checksum="AA82F510602D6A9F" modified="2013-05-29" version="1">MDNFSMELGKLSHQQVKEYYRRASKIDYVEKVSKVECHIGKMEHTAQYMSAEQLQMEAPSKENLVGMGDPATSYHMASMSHAWSLISGWELEDPNDWSHQVRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRY9</accession>
    <name>M5FRY9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PTR2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_18396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624752.1">
        <property type="nucleotide sequence ID" value="XM_040771357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRY9"/>
    <dbReference type="STRING" id="1858805.M5FRY9"/>
    <dbReference type="GeneID" id="63686419"/>
    <dbReference type="HOGENOM" id="CLU_004790_4_3_1"/>
    <dbReference type="OMA" id="EKDIGYW"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJT97854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="65676" checksum="B919E4BCB621F709" modified="2013-05-29" version="1">MNVDYESAPVGPKGLPPMNSPTEEKSALATALSHGEGDTDEGEEPTAEELLTLRKVPAGMPWPALAMCLIEFAERASYYGCTGVFSNFIRGPLPKGGNGAGAVAPGPLGYNESAGALGMGVQAATALTTLFTFLAYTIPILGGIVADTKWGRFKTICVGTAVGAIAHVLLVIPALPVVIAGGKAIAAFIIAMLILAFAAGFIKPSLAPLLCDQSPAHHAVIKRLPSGERVILDPQTTVQRYLLFFYWAINIGAFFSVATSYAERDVGFWLAYLLPGIIYMLMPIVLVVVYKRLYRAPPQGSVVLECMRVFKRLLSHGGWKRMWKGGDDFWNHAKPSYIEHTEGSVDLKVVFWDDKFVDEVRQSISACKVFLLIPIFALADGGFGSTENAMSAAMRVNGVPNDVISNFNPLTIVVVAPILNFGFYPLLRKFNINLAPMTRMSIGFILASINMIIAAILQWKVYQGSPCGYYATSNCQIGDGVANISLWAQVPLYSLPAIGELFVNVTSYEIAYTRAPARMKGLVYAMVLFTSALSSALTEIVNPALVDPYLIWPYVALAVATALAAIAFPTLFKHLNDPVEFNDIDRMEGRQQPLAKAQAAAESGDAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS97</accession>
    <name>M5FS97_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phospholipase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_24271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625576.1">
        <property type="nucleotide sequence ID" value="XM_040773617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS97"/>
    <dbReference type="STRING" id="1858805.M5FS97"/>
    <dbReference type="GeneID" id="63688679"/>
    <dbReference type="HOGENOM" id="CLU_008770_3_0_1"/>
    <dbReference type="OMA" id="TDGPWRY"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042578">
        <property type="term" value="F:phosphoric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16014">
        <property type="entry name" value="PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF1">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067247" evidence="2">
        <location>
            <begin position="18"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="647" mass="70625" checksum="3E7DB4DA2B3FA043" modified="2013-05-29" version="1">MLAFATFALSLIGTAFAQAATSLADIEHVVFFMQENRAFDHYFGTLYGVRGFQDPNAQINADGKSVFYQKVNSSLSNATDYLLPWYINYQGGDYLNGTQCMDGGSNSFENNHAAYANGTNDMWALDNNPASIAYFKRQDLPIHYAIADAWTIGDMYQEAQMASTWPNRVHWITGTVNIPGGPTNSTQGPVLDNNDTPGSCSHLTFTNFITDKTYETTTNVSCFPYDWVTVPEILQDLGVSWFVYQADDNFGCNELAAFKTFIEGAASPLNDTDNPLIVNGMTYSWSDNNDWQGGFTRFKNDAMSGNLPQVSWVIPTTELSEHPPYTPRQGAWLQQEIINAIQKSPIYNKTVLFISYDETGGWADHVLPFHSPAGTPGEWITDPLAGLSTFAGPGFRLPFYAISPYSRGGNVFTEVSDHTSQLLFLEKWAAARGTPFTTEAISSWRRTHMSDLTGMFDFTTFNSTPVVLPQGELPFTDGLTGLLAGAEYCQAKYEGNVNAHVPYGLQSETEALAVESGFRSVRGSVTEGRYLVFESAGVALAAADGLGVAAPLAQKETDATQRFVIHASNPLDADATVFSISSNGNYINAQLELDSAANAAVWNITFSASTMSYNIQDTNSGQYLSLTSAKPVLGSTAAPFKIYSVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS98</accession>
    <name>M5FS98_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_96687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624937.1">
        <property type="nucleotide sequence ID" value="XM_040777394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS98"/>
    <dbReference type="GeneID" id="63692456"/>
    <dbReference type="HOGENOM" id="CLU_024804_0_0_1"/>
    <dbReference type="OMA" id="PTGPEEY"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="633" mass="70399" checksum="425789BE0A25F808" modified="2013-05-29" version="1">MSAPFRTNHLSLNPKHARDHVEDNLEEYVKTAEFDKECAEKARKSALSSDKHSDSSSSEFDSLWSSSESESSVTTVESSPHAPSRIEAHLYYSGIRENGRGPKLIYRDSSDVYVEPTGPEEYKRLMRLVAVPDHHEFGNDGLWEKVRDKFVELLDDKEIRTTCIDFVKFTWLEKKKDGEVEVDEDEGENEAYQDGDRHFSNPTIWVGVAPNTLTADTAFEATKAIRAFLNGLNVTDIDIAYRETVPKSSVSPALFAPVGIVDHRKDFIDPVSVALSLPIAGLKTTMQGTIGPYFHVGNTLYAITVRHNLFLADRGNAEFRFKTSAPKIQVVLMGNPAFTNYLASIQAEIGTLIDPVDAIEKKVKTLTSNVHNGIGLPQSQIELNTHVAEHDRLRGKINALKDFFVDIKKRFGKITQRVIGHVVWAPPIGVGVAPHQYTRDLCVVQLHKESFSNLLGNVLSLGPEYTSTKLKSLLYERDDVDPTFKYPTDGLLALRNILTSQQISNPDNKSVAGDPIRRAIKRGFATNTTVGTISRFMSFSRKYFPIGNMESIESPILSHENETSTFSKGGDSGSTIVSPKGEFISLLTGGTNKGTDGSDITYSTVFEWVWELVREQFPGANLYWDDIPAFLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTH9</accession>
    <name>M5FTH9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aquaporin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_69850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626286.1">
        <property type="nucleotide sequence ID" value="XM_040775910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTH9"/>
    <dbReference type="STRING" id="1858805.M5FTH9"/>
    <dbReference type="GeneID" id="63690972"/>
    <dbReference type="HOGENOM" id="CLU_020019_6_1_1"/>
    <dbReference type="OMA" id="ILCSFPN"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF14">
        <property type="entry name" value="AQUAPORIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT99388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="35917" checksum="AA9FC01CF41D9E2B" modified="2013-05-29" version="1">MSRDIRHDVVFLNDLAPVPSHVTRWERIRYRDAHLLVQCLAEAMGTFLYCFCGIGSQAANTTGNINKLAGLGSVLQIGFAYAVGIMLALLIAGPTSGGHFNPCVTIANIVFRGFPLRKAPFYIVAQILGAFVACLVVYLQYRDVILQMEAGLAAAGELDAINFTAQGPAGIFGLYVTPGTNLGIVFWNEFSCDFILGLAIWACIDPTNFFAPPAMAPMIISVTYATIIWGFSPIGLAANSARDVGARIMVLCIWGTKAAGGPYAAIAALANIPATLLAAAFYEYVFRDCDRVVPSAQREYFGAMDSYAKRKEEGPTSFVSSDPELPIVASSEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU00</accession>
    <name>M5FU00_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_24069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625857.1">
        <property type="nucleotide sequence ID" value="XM_040773529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU00"/>
    <dbReference type="GeneID" id="63688591"/>
    <dbReference type="HOGENOM" id="CLU_3050274_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="5885" checksum="F9650EE23786384C" modified="2013-05-29" version="1">MSQPRILANESIAFGQNAETRSSLDLSLSHRSSYWSALEKAAVTNIVHELIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FU56</accession>
    <name>M5FU56_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_56513</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat UTP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625922.1">
        <property type="nucleotide sequence ID" value="XM_040775379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FU56"/>
    <dbReference type="STRING" id="1858805.M5FU56"/>
    <dbReference type="GeneID" id="63690441"/>
    <dbReference type="HOGENOM" id="CLU_011055_2_0_1"/>
    <dbReference type="OMA" id="DLNRATY"/>
    <dbReference type="OrthoDB" id="1935146at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="486" mass="52605" checksum="D7B76790A48CD068" modified="2013-05-29" version="1">MEAASEDEFPGEEEEEFHGFGSASSSGPEEDDNDDTDLSKPSPAPLSAPAVSSRKKAAWTDPSDSTLTVSLSSNRLRKLRQSAAEDSLSGQEYELRLRREFEKIQPAPEWAKPKRNKRVSEGEEGEEGIDSLLHGTADIVLPSSKSTSLPSGELQLTRLADANLSSPSSSSCMTSFHPSLSILSTASDRRLKLFSIDGARNPLLQSIHLPDLPLTKAVFNPQGTAVLCTGPRPFWYSYDLLSGQLLHSPRGLWGSPSAQNYEDGERSLEMCEFSPDGTLLAVGGRRGNIYFVDMRAGGASGQVLGSVKLNSAVTALQWTQPEGKEILAVGEEGEVYVFDVAARRCVRKWKDEGAFGASALAVSADGQGMALGARTGIVSLYDSSAMNTGMGQGNPKALRTVMNLTTRISCLKFNRSTEILCLASKDQKDQLRMVRIPVNTVFFNWPTSGTPLGHVTSVDFSASDEYAAIANTRGKVLLYQLRHYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUT7</accession>
    <name>M5FUT7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_69680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626172.1">
        <property type="nucleotide sequence ID" value="XM_040775905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUT7"/>
    <dbReference type="STRING" id="1858805.M5FUT7"/>
    <dbReference type="GeneID" id="63690967"/>
    <dbReference type="HOGENOM" id="CLU_001882_4_1_1"/>
    <dbReference type="OMA" id="EVYWVTH"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000007">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="244"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="712" mass="79128" checksum="D443428971FDA945" modified="2013-05-29" version="1">MAQSILSRAHAHSPSTSPATWREALEATKGVPDSFELLKVLVFKPRTAKNVAPVPVIVIAREETETNSTALGKKLNLKEMRLATEDLLVEVFGVNKDGISPLSLTAENFPKVLTVLDGSLASAAGPFAVHANSDKETVFLHGQEIVGYLRSLEVTDTKITEVDFVALKADATANAPLKDAIPAQAKTATTSRKEDAKIEGAVQIAVGIQKELDFPGWYTNVLIKSDMLDYYSVSGCYILKPWSYSIWEAIQQWFDGEIKEMGVENAYFPLFVSAKVLEKEKDHVEGFAPEVAWVTRAGNTELEEPIAIRPTSETVMYPYYAKWIQSHRDLPLRLNQWNSVVRWEFKNPQPFLRTREFLWQEGHTAHLTKEGAGEEVLQILELYRRVYEELLAVPVIPGIKSEKEKFAGGLYTTTLEGFISTTGRGIQAATSHCLGQNFSKMFNIVVEDPNAGTGENASKIFVWQNSWGLSTRTIGVMVMVHGDNQGLVLPPRVASIQVIIVPCGVNAKTSDEMRKRVPEECDALAKKLKKAGIKAKADLRDGYTPGYKFNDWELKGVPIRLEIGPADLEKQQTVAVRRDTGAKTPLKMATAVEDVKQLLETIQSDMYNKAKATYNSRVKIVTEWKDFVPTLDSKCVVIMPWCEIEACEDDIKERSGRVPAGEQVDERAPSAGAKSLAFPLDQTKYPKIEHGKTKCPACGENAKRWMLFGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUY8</accession>
    <name>M5FUY8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC1-like cysteine cluster associated with KDZ transposases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626257.1">
        <property type="nucleotide sequence ID" value="XM_040770522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUY8"/>
    <dbReference type="GeneID" id="63685584"/>
    <dbReference type="HOGENOM" id="CLU_315680_0_0_1"/>
    <dbReference type="OMA" id="HERWTEN"/>
    <dbReference type="OrthoDB" id="2505969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="925" mass="104364" checksum="98065A5AC6D22DD5" modified="2013-05-29" version="1">MASTSGSLSTGSPHTLEEHLLSRPTPNPRPRSTTTRSRLGGSLVSGPVQRATGPRRAAGPIRISVAHSHLGSQADLQAPSLEELLQQPIPPPPPLRRGRKRRDTYSVAALDRRSTQIRAQEDERLAADPHEAEAIRFVQDKFSMSLAEDSAGGAWEDVEMGDGGEEEETLYREWVEVTRQTYTSGEGLYARRILQQATTWSLLMDELIPPESRRTFELQVVSWTGLERRVFGAVDRHASPVRILLRHGFLARSPEVPRMAVNIRILEVYHQARLRGYMSLEAWTRVVCDLHGAPYEPSFRRRMADAYDAYTLLLVAVEKRVSQGFGRDTPDWRVKHTCPACSYKLQDEPSLPFSRLLCGDGNNSSKRFAYAGHQDLRVYESDYILPIEHVERFKNDVRSHQTSRQNRRTSREGDPTDGLRPEEGTKIGLDETLGACADKWKPSQARESGQIFQQALAETGHFLTVCRHAFICYSVDMIRSGELAKYSIASLDRLIDIYGADIAFGYDIGYWFYHTWDSDRRAVLGEFIFQNYRQALKIIQTEGPAVGTLLKNLNLTSNDLDQFCLDEKNFFSNLQREPEMDEKAFDYLDVLKLLQSARDDLAASQAQSFNISTPEQWSQGAIQNQGRSNERLHLQKLRKVLELDAIATNSEENLNTERWTPDHPSWVHYSRAAQHQEFQRALDHLESLVVQRLFEMEKVNARGTNYKMRTSIAKALQSRSTAIRTALGNYNPVLDHAFLGEFTILRHGSEASDASRRWMVPQVWEVVVKHLLLKCAREEIRRLDVEVRRVLTAVEDKLQDMQRHVDQIALSGNAALAAKMRSRVEERSSINTRVLKRLQDITRLPGYSGSYVRGVPVSGMYGDAGPGQGTRCDGEEVESPCPERSGALRSTVHGPDASGEEEDCSIQDIEALAHAFAVGVSFPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV04</accession>
    <name>M5FV04_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_22674</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628498.1">
        <property type="nucleotide sequence ID" value="XM_040772918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV04"/>
    <dbReference type="STRING" id="1858805.M5FV04"/>
    <dbReference type="GeneID" id="63687980"/>
    <dbReference type="HOGENOM" id="CLU_035750_12_1_1"/>
    <dbReference type="OMA" id="MKRDHDK"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU01601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="195" mass="21984" checksum="811A75E6BB37CC0F" modified="2013-05-29" version="1">MAECSFGLVGKGYVLIASDTSASRSIVKMKENEDKIKGLGPNLMMAYGGEPGDTIQFAEYVERNLRLYHIRHNHTLRPASAAAWIRRSLADSLRSRHPYSVNLILGGYDHTSSMPNLYWIDYLGTMVEVPFAAHGYGAYFALATLDRFHDPEATLEEGLETLKRCINEVEKRLIISLGKFMVKIIDRNGMREVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVD4</accession>
    <name>M5FVD4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Creatinase/aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_59274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624184.1">
        <property type="nucleotide sequence ID" value="XM_040775549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVD4"/>
    <dbReference type="STRING" id="1858805.M5FVD4"/>
    <dbReference type="GeneID" id="63690611"/>
    <dbReference type="HOGENOM" id="CLU_2580319_0_0_1"/>
    <dbReference type="OMA" id="GIYFPPH"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT97286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8015" checksum="C85FA7286740DF5B" modified="2013-05-29" version="1" fragment="single">TVEPGIYFSPHQLAPIRSSPYIDHPLLSTYESVGGIRLEDVVLITEEGCENLTGCVKGLEEVERLASGAWGAGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVG5</accession>
    <name>M5FVG5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_119444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624219.1">
        <property type="nucleotide sequence ID" value="XM_040770790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVG5"/>
    <dbReference type="STRING" id="1858805.M5FVG5"/>
    <dbReference type="GeneID" id="63685852"/>
    <dbReference type="HOGENOM" id="CLU_015429_0_0_1"/>
    <dbReference type="OMA" id="QTWQAAN"/>
    <dbReference type="OrthoDB" id="3358963at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="674" mass="75157" checksum="14B456A86D9ECAC9" modified="2013-05-29" version="1">MPKVTHRKSAAIHHNVDDNIGNTSATVVADGGKTLSKECDADIFVDPMLGGPLPMFVERDVSDAPKLIDLIMKHGGQVSSGYSNVNYIIVNPLSNSGKNLARQYAGKKGKVVLASNWITECIRKGELLTFKSDWAGFRLDGYDSNERPQTAANILSSVSRPMEPIDTPVTVPPRGKKRPRQSEPEVPAVPPPPLPQAPSPSLPPNVYPLTVSQIATQQPLGSWQLPQNLPPPGMAPPPMQRMPGYPPGAIAPPPQMQPATLRPPWETFSAPPPPGYAFHYPAPGHWDENPYYPHFQAPPPPPPAYPPEEAYVGQPFTTPPSDAAEHDAAAEVERGRSIHRASRTSTSRQSIAQSGASRTFRKPLARSPTPPTRIMKSTFGGNLFTSEDILYLKKYIDYCQQQGLILSLREICERLAIRAPHHTFYSWRRFCNKHQIKLGAYDMSVFKASVEPDVDGEESGESGLERDGEEQDDDEDEEVRNAILGPTPILSPLAPGRGRTVQAPAASGYLEQSRDRSPTPPKTLYRSTTGKGVAFTEEDVRYLLRYLQYAQGQDMVQVWRDIALKAPHHSRASWMKYWRRHKHEFDTDRPPTLPQAGPDEPATKRRRYDREDDIKLARLMLGKPAGTSDQIFQSFAMLPENAHHPWKGWQEHHRIHKAKIDHVLQQMELGTFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVJ1</accession>
    <name>M5FVJ1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartic peptidase DDI1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_54541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627216.1">
        <property type="nucleotide sequence ID" value="XM_040775271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVJ1"/>
    <dbReference type="STRING" id="1858805.M5FVJ1"/>
    <dbReference type="GeneID" id="63690333"/>
    <dbReference type="HOGENOM" id="CLU_003921_0_0_1"/>
    <dbReference type="OMA" id="PNTTIMI"/>
    <dbReference type="OrthoDB" id="5596707at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181149" description="Aspartic peptidase DDI1-type domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="24873" checksum="C60D03AF7A631862" modified="2013-05-29" version="1">MLNVLMTLTFRELLAVSPDVRKMVNYQTSVHWTQCGVQPVFLQEDTDSIDTMAVTDGTCCKAVQAKDVPTWAHTLHISSNDAPASMVIGKTIVPLCAIKLLVSDNDMKMHGCLDSGSVLVAMNYNMWKDLKVPYYPDSVINMESANDQASSTLGCVHNLCVTIGPISLFLQVHIVCKSPFDLLLGQPFLTLLKCQSLDLLNGDQQLMLTCPNTTIMIIIPTQNWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVQ7</accession>
    <name>M5FVQ7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_33231</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ORC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624344.1">
        <property type="nucleotide sequence ID" value="XM_040774371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVQ7"/>
    <dbReference type="STRING" id="1858805.M5FVQ7"/>
    <dbReference type="GeneID" id="63689433"/>
    <dbReference type="HOGENOM" id="CLU_012774_5_0_1"/>
    <dbReference type="OMA" id="QPIINGE"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000199">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="40"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT97446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="251" mass="27687" checksum="5A952D822CA84A52" modified="2013-05-29" version="1" fragment="single">PWMRALATLHVSATPDDLPCREQEFESVLGKVEGLLEEGEGGCIYISGVPGTGKTATVHAVVRTLHARAQASEIPPFTFLEVNGLKLTGAREAYAELWRVVSGEEKRVSPGEALRRLVGYFERSGKRGPEAGCFVVLMDELDQLITTKQDVVYNFFNWPTLPSSRLVVLAVANTMDLPERVMAGKVRSRLGMERINFAPYTRDQLKEIVLSRLRGGILQAEELMHPDAVQIAAMRVAGVSGDARRILDISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVQ8</accession>
    <name>M5FVQ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">DNA topoisomerase 2</fullName>
            <ecNumber evidence="5 15">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_54567</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5 15"/>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627326.1">
        <property type="nucleotide sequence ID" value="XM_040775274.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FVQ8"/>
    <dbReference type="GeneID" id="63690336"/>
    <dbReference type="HOGENOM" id="CLU_001935_1_1_1"/>
    <dbReference type="OMA" id="TWTQDFK"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 14 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14 15" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="17">
        <location>
            <begin position="542"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="18">
        <location>
            <begin position="792"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1252"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1257"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="14">
        <location>
            <position position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU00429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1365" mass="153952" checksum="A41F1EBC5C33CD16" modified="2013-05-29" version="1">MASDDEFDMDVTLDDGDESDFVPAAKKKTAPKAAPKPKAAPKPKVDSSKPKSATKPKAAPKKKKEPLHPIDENQMDSIVMDEEFDFGPPDPIEDDMPSVSAPKPKQKKNASEIYERLDAVEHVLKRPDSYIGSVERKTDLIWVLDPETKRMVNRSTKFVPGFFKIVDEILVNAADHKVNEAAMDTLKVVIDREKKSISVYNNGAGIPVEMHTKENMYIPQLIFGNLFSGSNYDDTEKKLTGGRNGFGAKLANIYSHEFTVETADSKNGKKYKQMWKDNMSICGKPSITNYSKSDGWTKVSFTPDLARFGMTEIDDDTYALLCKRVYDLAGTIKDVKVFLNDERLRIKNFKQYIDLYLNSVAEANVESGATAQPKQTVVYEQLNPRWEVGFVVSDGQFQQVSFANSISTIKGGTHVETIASQISNKLLTAIQKKNKSAPVKPFQIRNHMWLFVNCLVENAAFDSQTKDTLTLKSTSFGSRPTITDEFMKKVAKSGIVENVLEYAKFKADQAHKKTDGTKRSRLVGMAKLVDANNAGGRNASKCSLILCEGDSAKTLAEAGLAVVGRDNFGIFPLRGKLLNVREANHEQIMKNAEIQAIKKIMGLQHNKVYDSVDSLRYGSIMIMTDQDFDGSHIKGLIINFLDHFYPSLLKIPGFLVEFITPIVRVTHKRTRKRTTFFTMPEYEEWAEQHKHDKHLYEDPKYFKGLGTSGPEDGMEYFGNMETHLIPFHPTQEGERELIDMAFSKKKVEARKDWLRNFKPGTYMDHSVDEITYDDFINKELILFSMADNIRSIPSMCDGLKPGHRKVLFGVFKRNLKNEIKVAQLAGYIGEHTAYHHGEQSLHSTIIGMAQNFVGANNLNLLIPSGGFGSRSMGGEDAAAARYLNTNLMAITRSVFHSADDNILTYLMEDGKRIEPEFYLPIIPMVLVNGSSGIGTGWSTNIPSFNPVDIVANIRRYMRHEPLEPMSPWYRNFLGSFEKVSEGKFVCHGIIKKVDDYNVEITELPIGRWTQKYKEMLESWIMGDDKTAATIKDYKEYHTTRHIRFTVQLSGTEMQKAEAEGLEKYFKLLEAISTTNMMCFDADGKMRKFNSPEDLIEDFCPLRLKFYQKRKDYLADQLMVELEKLNNQARFVKMIIDRELVISNRKKVDIVAELRKKELKPFPKVSKAKEEGETEDVVEEEEPGSVTDFDYLLGMAIYSLTQERINRLLLDCERKEGELKALLKQSPQDIWNNDLDVFLEKWENLLEDDVAMQNNENRKKKGKQGATIRTRKSVGKGKKRADDHSDDDFIPAKAPSKPRKPAAPKPAVAKPTAPPPKAEEISDDSLMDVDSSPVAARAVGKGKGKAAVKRGSYVSYCRTPSGANPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVT6</accession>
    <name>M5FVT6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Het-c2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_112012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624374.1">
        <property type="nucleotide sequence ID" value="XM_040769328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVT6"/>
    <dbReference type="STRING" id="1858805.M5FVT6"/>
    <dbReference type="GeneID" id="63684390"/>
    <dbReference type="HOGENOM" id="CLU_079400_0_0_1"/>
    <dbReference type="OMA" id="EMHGAEW"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="22206" checksum="8836560129BE9C2C" modified="2013-05-29" version="1">MPTYFDTIAMNFANVEVGPDGIETVQFLQAAEALSNMFTLFNSTAFSVVQSDINGNIKKLRERYDATGEKSRTIEMLVVNEQGEKNRTATQGLLWLNRGLRFTYVGLKHSYDHADSALSESFNISYGETLRAHHSFITRGVFSVAVRAVPHRASLLKSLGEPEDRVLQQLDEWLNALGQLTQRIDKFFETSDYAKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVU2</accession>
    <name>M5FVU2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_100200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628858.1">
        <property type="nucleotide sequence ID" value="XM_040767435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVU2"/>
    <dbReference type="GeneID" id="63682497"/>
    <dbReference type="HOGENOM" id="CLU_783082_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="354" mass="38414" checksum="CFF258F90B221DB7" modified="2013-05-29" version="1">MSAVVMEEAPPSSAIALHPLGPVDEAKLCLVTAELITALNDTRSAKKIVKDTRKAGGKAPVIEVVEGEQGSSLVGRKDKQQQLLKDGLADAARMRVEEVRAGLETALAQKQTVERVDQASSSFCALTTCRSFPSRSSSTPSQPLLPFPVAPSHLGPPRPQILRSKSTPTPVPLTFSSSSVVLRLIFAWRPKKRCWQRKERIAPLETTLGYRRVAEKRAEEELEAREGILLAHKREFEAQGHKLRGKAAKEFHAAQPKKKVSEKLTFERNRLRFKRSQVKESVKTGGKKVWTFTKKVPGLLRDNAQAIANGVAECAAHFCGHIVRVTLGIPPVTAAIPGALVGAAAALKAAAGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWK0</accession>
    <name>M5FWK0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_111307</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624689.1">
        <property type="nucleotide sequence ID" value="XM_040769208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWK0"/>
    <dbReference type="STRING" id="1858805.M5FWK0"/>
    <dbReference type="GeneID" id="63684270"/>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF51">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="64"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="552" mass="60844" checksum="A14D12888A96ED23" modified="2013-05-29" version="1">MSTVQDKKPGRDSQYIEESDIIEKGGPSSNNNAHDARVLAKLSADDKSLNTVAAIRKYWVAFLWAMYASVGSAIAGYDITVSGAVVAIPSFRRDLGTFIDDQWVISAAWQSGFNAGSNIFQALGAFATGFIGEKIGRKGSLLVASIISIAALFLQFFIRPHDFVMFFFGRSINGFAVGIYTTIASSYCAEVSPLALRGVTTGAVNFWILVNCGFISYKGNCTHRTVQLVKLDHPGNREPRRLLRVSYSTCRAMVLPGIRLGLPSLRAESPWYLVRRERMVDAKKASERLFGGTGLDIDLHLIYIKETIELEERIAGQGKWVDLFRGTDLRRTIIAGMVFICQEMVGVQFVLGYSVYFFDLAGFNDANAFHLGVGTMALAIVGNLIGIGFTNRLGRRPIFFWGMVACTIDTLMIGVLSLVPGNGALWAMGVFTMLYMLTYQAGIGPLAYCIFAEISTARLRSKTVAWGVVINQIGALIIQVINPYLINPDEANMQGKVGWLFGGLGVIFTIWSWFGVPETGGRTIDEIDILFEKRIPARQFRSYVIQDADRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWN2</accession>
    <name>M5FWN2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspergillopepsin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_91302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624734.1">
        <property type="nucleotide sequence ID" value="XM_040777004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWN2"/>
    <dbReference type="STRING" id="1858805.M5FWN2"/>
    <dbReference type="MEROPS" id="G01.002"/>
    <dbReference type="GeneID" id="63692066"/>
    <dbReference type="HOGENOM" id="CLU_066466_0_1_1"/>
    <dbReference type="OMA" id="SLNWAGY"/>
    <dbReference type="OrthoDB" id="2862635at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067324" description="Aspergillopepsin" evidence="2">
        <location>
            <begin position="19"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT97836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="28133" checksum="0B5398AF5E34CF06" modified="2013-05-29" version="1">MVAITLLTSALFATAALAAPSSRSRLEQRMARRSLGAHLSTPNQRITAATDFTGPKTEATTAYSSNWAGPVYNANAGTYKAVTGTFTVPTPSAPSGGRGSYAASAWVGIDGDSCDTAILQTGLDFTIDNGKVSYDAWYEWYPDYAYDFSGISFSAGNEVRVTVTATSTTSGTAVIENLTTGETVTQDITSSSALCEQDAEWIVEDFTEGNSLVPFANFGSVAFTSAEATTSSGSTQGPSGATYIFDIEQNNKVLTSVTTGTSTTTITYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWY2</accession>
    <name>M5FWY2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cyclin-dependent kinase 8</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">DACRYDRAFT_24881</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624869.1">
        <property type="nucleotide sequence ID" value="XM_040773894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWY2"/>
    <dbReference type="STRING" id="1858805.M5FWY2"/>
    <dbReference type="GeneID" id="63688956"/>
    <dbReference type="HOGENOM" id="CLU_000288_181_6_1"/>
    <dbReference type="OMA" id="YFKNGGP"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="34"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="406"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EJT97971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="482" mass="53443" checksum="7D9526C2219A1C46" modified="2013-05-29" version="1">MAVSSTATGLDTNPLMAAYKRRRDTSRLGVASKYESQGFISSGTYGKVYKVLLLPQAVAAPRPGDLKGEAGAFYAVKKFKPEKEGGEGYTGLSQSACREIALNREIGHENVIALREVILEMKAVFMVFEYAEHDFLQVIHFHSTSHPRSVLPLGVLKSLLYQLLNGVAYLHSNFIMHRDLKPANILITDDGIVKIGDLGLARVFHRPLVPLLNGDKVVVTIWYRAPELLLGAKHYTTAIDMWAVGCIFAELLSLRPIFKGDEAKMDASKKLPFQKDQMMKIMDVLGAPTVDEWPLLSWMPDYPQLQAMERERARQDPSKPRFENNMGIFLNRYMRSMDTGRAALQELFTWDPDKRLTAADALNHPFFTTDAPAPTKNAFAYATKPYPTRRITADEGGLFAEPAAHAPPAQTANTSATSQRPAAPPAPLAGQPQASTTLVGTSAVGLPGARMWTTQQQAQQQQQQQQQQQQQRGMARKRPRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX59</accession>
    <name>M5FX59_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627222.1">
        <property type="nucleotide sequence ID" value="XM_040773171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX59"/>
    <dbReference type="GeneID" id="63688233"/>
    <dbReference type="HOGENOM" id="CLU_2704749_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="73" mass="8303" checksum="208BDC5D4671F937" modified="2013-05-29" version="1">MHLRRPHVIPMRLGLRVGCRRTHPLQLIQRCRFLVKSGISMQIFVPDSPYEFDGLCACFTADATIGVTFLAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX71</accession>
    <name>M5FX71_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_99681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629475.1">
        <property type="nucleotide sequence ID" value="XM_040777612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX71"/>
    <dbReference type="STRING" id="1858805.M5FX71"/>
    <dbReference type="GeneID" id="63692674"/>
    <dbReference type="HOGENOM" id="CLU_073647_1_0_1"/>
    <dbReference type="OMA" id="DYICASH"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="27889" checksum="8C2400E1E68E3A2F" modified="2013-05-29" version="1">MIPLDHRQPVLFDRSRADEPYIPLPSHHDNIRLTPWRVEDVDAVLPILNHPDVYPRLVGPAYPYTREHAQLWFEGQSKLFEPDRGYFTGDEAAPLRQGKFFDYTPMCVIREVQPDGSQIFLGVVDLVRSSFGGETDSATKEQLIKKNRGKTAGDPTIVYMVGDYLAASHHGKGIMTAAVRELIRSWGVPYMRIRLVHAAVMEGNVGSRRVFEKLGFSFSGFIEGSVPTQGKRDEVMGEWFFQYTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXD2</accession>
    <name>M5FXD2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627332.1">
        <property type="nucleotide sequence ID" value="XM_040768824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXD2"/>
    <dbReference type="STRING" id="1858805.M5FXD2"/>
    <dbReference type="GeneID" id="63683886"/>
    <dbReference type="HOGENOM" id="CLU_015676_3_0_1"/>
    <dbReference type="OMA" id="PARDEYK"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="616" mass="66776" checksum="E7B612720E242320" modified="2013-05-29" version="1">MEPAEALPFPQPPIPANLNPEAIAQHWLNGLNTAIRGVSVAGPSITITTVSEAVSQLFSDQPKAFWKDHLALSLDLRTMHGHTQIITLLLRCCSPEAGMHIGSFAMPGEGEGPRAAWVQPASGYVELWFGFQTRVGECKGVAKLIPTLPPGQAELKWKAWTVYTELVSLRDLPFDRTRLEKRSATEGLAGPRDVDVVVLGAGQSGLQVAAHLLALGLSVLVVEREAQVGNQWDGHYAALKVHVTKWFYQFPYLNFPPEMPTYPSGEEMASYLRLYASKLHLPVRTATQVLSASFHFIHSASTDGKWELSMKPSDGPAENWTCRYLVSATGLSGKVPNMPEIPARDEYKGIVLHSSQFRTGEGWAGKKAIVVGTGCSGHDIASELYRCGAKVTLHQRSPTMVLPPTFVHITQDSIFTPDADLDAADREWNATPLQVVARLGPLLPTGDKAKEIENGLVKRGFQMKEIDFTKAVYERIGGLYIDVGASELIVDGKIAIKSGMPIVSYTPTGLAFADGTTLDANLIVFATGFNISVMRSTIVSIVGSDIGSTLKSPWGLDREGHLLGVGKFSGHPNIYYMAGEAQMSRTSAKLVALQLTLAKQGLLNRVDIPYDIATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXI2</accession>
    <name>M5FXI2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD/NADP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_50706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629610.1">
        <property type="nucleotide sequence ID" value="XM_040775004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXI2"/>
    <dbReference type="STRING" id="1858805.M5FXI2"/>
    <dbReference type="GeneID" id="63690066"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OMA" id="MTGWMGP"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU02716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="478" mass="52854" checksum="1724E6A2D5DB3271" modified="2013-05-29" version="1" fragment="single">LGGLAAAFALQKAGHRCTILEQAPAIGEVGAGIQVTPNVSRILLSWGLGPQLERTAVIPGAIVFRRWTTGERVGYTSWADITKTHGAPYCHVHRADFHKMLYDLALGAGVTIRLGSLVTSIDPDTPSVTLRSGEVLPCDLLVGADGVKSGIRQVIVGSPDAPVPTGDAAYRATIPTSLMLSDPELAGFVQTPEMTAWMGPGRHIMGYCIRGKKEYNLVLLHPDDGSVESWTAEGSADKMRADFEGWEPRIQKLLAFVPSTLKWKLMDRGPLETWIHKSGKVVLLGDSCHPMLPYRAQGAAMAVEDAAVLGSLFTHLSSPSQIPFFLQAYEQLRHARCTDTQAQARLNQKIFHLPDGEAQETRDADMCRAMEAELSGEALEAEGSQNQWADRKKSRVQFGYDAEGEAERWWNEEGKQDLQRLQELKLKELENVQEEQAQPHEKAEGIEMETVVNEPEKEHEQERTHEPEREIEQAQEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY16</accession>
    <name>M5FY16_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_24503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625349.1">
        <property type="nucleotide sequence ID" value="XM_040773702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY16"/>
    <dbReference type="GeneID" id="63688764"/>
    <dbReference type="HOGENOM" id="CLU_3050275_0_0_1"/>
    <dbReference type="OrthoDB" id="10423017at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="54" mass="6534" checksum="FFC86F921892AAA0" modified="2013-05-29" version="1">MWEEERLKAFEWIRLKKVSRRVALAQQVQAIRRRSSSNPEDEEEAETETKEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYA1</accession>
    <name>M5FYA1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylacetyl-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_25695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795902">
        <property type="protein sequence ID" value="EJT96507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623405.1">
        <property type="nucleotide sequence ID" value="XM_040774262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYA1"/>
    <dbReference type="STRING" id="1858805.M5FYA1"/>
    <dbReference type="GeneID" id="63689324"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OMA" id="PEFWIAG"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="487"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT96507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="602" mass="66159" checksum="5E8CCBC34D74E6F1" modified="2013-05-29" version="1">MADFQPLMSHPHPYPHDLTIPQFLLDSPSHPLRPTRLAGSRWLVDDDTSRAYGLEEIRERVERVARGIRAQFGVGEGDVVCLFSQNHIDYPIVIWALHRLGAVVSCANPSYTAGELTYQLRETSSKLLFTSPSALPTALAATAEAGLFSQERVVVFGPPPPEPQLDGQGCFFSSQPEPTWDTKDGQFLTVQQISLLGWHSPPNYVEPRGPMVGDSVAFLSFSSGTTGLPKSIAIAHRNLIANVIQVVAHNRTNEEGLSREDRFAMPGEVALGVLPMYHIYGLVVNLHVVLFSGLALVVVPRFVFKNILESIVRHRVSHLYIVPPMVVMMLNNPLTKSYDLSHLRFAMVGAAPLSREVTERFKKQFPRVRMGQGYGMTETCTVVCQFEFQKESVNGSAGKLIPHTQARIILPSGRPAGPGEPGELWVKGPQTALYYPNNKAATEETFLPDGWVRTGDEALITKEGDVYVLDRLKEFLKVNGFQVAPAELEGHLVVHPYVSDAGVVGIPDDMRGEVPIAFVVLSPEGKAAASGAGAAGEGNASEEIKKWVRDQKVRYKWLEGGVVFVDAIPKNTSGKILRRLLRDQAKEIVQARKKGMVVLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYC5</accession>
    <name>M5FYC5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_60363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795889">
        <property type="protein sequence ID" value="EJT96527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623425.1">
        <property type="nucleotide sequence ID" value="XM_040775627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYC5"/>
    <dbReference type="STRING" id="1858805.M5FYC5"/>
    <dbReference type="GeneID" id="63690689"/>
    <dbReference type="HOGENOM" id="CLU_130521_1_0_1"/>
    <dbReference type="OrthoDB" id="2847449at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="71" mass="7539" checksum="4E7DB3AE4C103267" modified="2013-05-29" version="1" fragment="single">YAPNAMNSLLSAGHFDDIGGKISFSAAKCELRDVKGILVGTGQKTNHLYLLNAKAELVQSSGDQTHQAAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYF7</accession>
    <name>M5FYF7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_21407</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629975.1">
        <property type="nucleotide sequence ID" value="XM_040772381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYF7"/>
    <dbReference type="STRING" id="1858805.M5FYF7"/>
    <dbReference type="GeneID" id="63687443"/>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_1"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11610:FF:000009">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="645"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="971"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU03081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1017" mass="114006" checksum="01D35119A231605F" modified="2013-05-29" version="1">MLARQLGRRAVRKGVRSSLVRSFTSTAGRSLATPSAAPPSPNDPFANGTNAYYAEEMYRHWKQDPKSVHISWDIYFSGMDKGLPSEQAFQPPPRPGAEEEELKLEGPSPPTLSLGGGTQVSDHLKVQLLVRAYQVRGHHIANLDPLGVMDADLDTSVPAELTISHYGWTEADLDREISLGPGILPRFAVGGRNSMTIREIIDVLKGIYCGAVGFQYIHMPSREECDWIRERIEIPKPWDYNVDEKRMILDRLMWSESFEKFIASKYPNEKRFGLEGCESLIPCMKALIDRSVDHGVKNIVMGMPHRGRLNVLANVIRKPIEAILHEFSGDVAADDSAGGDVKYHLGANYVRPTPSGKKVALSLVANPSHLESEDPVVLGKTRALQHFDDDEVSHNTAMGLILHGDAAFAGQGVVYETMGMHSLPNYGTGGTVHVIVNNQIGFTTDPRFARSTPYPSDIAKSIDAPIFHVNGDNVEAVTFVAQLAADWRAKYKKDVVIDVVCYRRYGHNETDQPSFTQPRMYQAIEKQPTTLTQYTKSLIDESTFSEKDIDEHKKWVWGMLEKAAAAAEHYKPSPKEWLSSAWNGFPSPKELAEKNLPQSETGVSEDILKRIGQTISSTPKGFHPHRNLARILATRGKTVEEGKNIDWPTAEALAFGSLALEKVHVRLSGQDVERGTFSQRHAVIHDQETEQQYIPLNHLGSDQAMFKVCNSHLSEYGVLGFELGYSLVSPDCLTIWEAQFGDFANGAQVIIDQYLAAGERKWAQRSGLVMSLPHGFDGQGPEHSSGRLERFLQLCDDNPYIYPSEESISRQHQDCNLQIVYPSTPANCFHVLRRQTHRDFRKPLIFFWSKSLLRHPMARSSLDEMTDDTQFQRYIPDPHPESLAPPEEIKKHILCTGQIYYQLLKEREDRGIKDVAISRVEQLAPFPYDLLTPHLDKYPNAELQWLQEEPLNNGAWTHVAPRLRTACSKTEHHQGKDIAYGGRPPYSSVATGSKSVHKKETQNYLNQAFGEDTAVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYJ9</accession>
    <name>M5FYJ9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24229</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625519.1">
        <property type="nucleotide sequence ID" value="XM_040773601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYJ9"/>
    <dbReference type="STRING" id="1858805.M5FYJ9"/>
    <dbReference type="GeneID" id="63688663"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="OMA" id="DIYPKSI"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF12">
        <property type="entry name" value="L-ARABINITOL 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="44"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="385" mass="41781" checksum="0481F7B8903F4396" modified="2013-05-29" version="1">MAAPINPFYDPATTLNSSQFHIFPHGQFPPRDGKQNLGAFTNPGHELHLVQKPVPVPGKGQVVVHVRATGICGSDVHFWKHGRIGDMVVCNENGLGHESAGTVFSVGEGVTKWKVGDRVAIEAGVPCSLPSCDFCRTGRYNACPDVVFFSTPPYHGTLTRYHLHPAAWLHRLPDNVSFEEGALLEPLTVALAGIERSSLRLGDPLLICGAGPIGLVTLLCARASGAEPIVITDLAASRLEFAKQLVPSVRTILIKREETSKDVAKRVRATLGIEPSLALECTGVESSVHAAIYSVRFGGMVFVIGVGKEMQSMPFMHLSANEIDLKFQYRYANQYPKAIRLVSGGLLNLKPLVTHRYSLEHAMEAFDTASDITKGSIKVQILDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ46</accession>
    <name>M5FZ46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_106475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630210.1">
        <property type="nucleotide sequence ID" value="XM_040768274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ46"/>
    <dbReference type="GeneID" id="63683336"/>
    <dbReference type="HOGENOM" id="CLU_1111366_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="250" mass="28130" checksum="1A9F0DC91AEF04FD" modified="2013-05-29" version="1">MLDVSRLVHLTLECCREVGIPTSINSTPFITFFKRLTELRSLSIDCFALPPTFPHEGDQEIIYLPNLTTIKVCNTTRSNSYAWLAQFLMPSLRSVEMAPSFPNVRVPSAAQYFATMRTFFSIIPNVANVTMTVRGGDSATTGIFQLLLEEVLPRLQTFKLRVQDEEYGSSSVDQDSVPWSKNNPRDLKLLVNERWQQGRMLSELRVDPPLFPGDNVGKNYALELLRPMAEIGGEAEFGLEDLFGRCTSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ60</accession>
    <name>M5FZ60_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_101515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625759.1">
        <property type="nucleotide sequence ID" value="XM_040767562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ60"/>
    <dbReference type="GeneID" id="63682624"/>
    <dbReference type="HOGENOM" id="CLU_1343204_0_0_1"/>
    <dbReference type="OrthoDB" id="10503831at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013869">
        <property type="entry name" value="DUF1757"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08560">
        <property type="entry name" value="DUF1757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="204" mass="22328" checksum="9385BDCEED81BF01" modified="2013-05-29" version="1">MSNQFEPRTFLRLHARDPDDDPSPGTARATNYVILQGHVALKGAHAGALLGPLATFIRYWGRPTTTQMLRGSVAFMGWTAAIATIAGVARVWSAEPYAIFDRAYRLNNNLSQNRVDRISLFSAGLGSALGSFFLPGIIPLRTRILGGFATGLAGGVLVHVISASIWAEDEEMTRRVQLERQAFKEKIMALKESKKGEEAKEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ77</accession>
    <name>M5FZ77_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_56618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625774.1">
        <property type="nucleotide sequence ID" value="XM_040775381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ77"/>
    <dbReference type="STRING" id="1858805.M5FZ77"/>
    <dbReference type="GeneID" id="63690443"/>
    <dbReference type="HOGENOM" id="CLU_004624_7_1_1"/>
    <dbReference type="OMA" id="WMLPAEW"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF42">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="419" mass="46560" checksum="3355EF085C651E20" modified="2013-05-29" version="1">MGLTYVPPSTPFQLLSTCLQLGSWLVFEPWMAVGEWQSMGGEYCDDCSTCLGSEWSLANYLGQEKTNAVFKEHWYTWLTQTEVDDIVRFKLNTVRIPLGFWIVEGIVDRSLEPYAQGGLQQLASRFSMLKAANIAVVLDHHALPGVATPLQMFAGNCTTIVEFYTDYNYQRGVTWTAVMTYLSHVHPAFSTVFAIEAVNEPIMDYTQTPDYSRYQVNFVMAVRAVEAALGILGLEAPLLSSLLPSPQGYGSLSHLLNEHGAECLVTNFMNRDWQYSNDPSDPVANPADAAKGPATYDNHLYFSYGGVADPNAESYLQTICNMNRTLQSAAIGDAPMWFGEWSLAVNFNTTNSFLQQWSDSQKFIYSQSAGWIFWALKIANDATAPPTQWSYIDAVNAGIMNPDPAALFNSSICDPYINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZB9</accession>
    <name>M5FZB9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="2 11">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_24031</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="2 11"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625814.1">
        <property type="nucleotide sequence ID" value="XM_040773512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZB9"/>
    <dbReference type="STRING" id="1858805.M5FZB9"/>
    <dbReference type="GeneID" id="63688574"/>
    <dbReference type="HOGENOM" id="CLU_095024_0_0_1"/>
    <dbReference type="OMA" id="LDYEWQP"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000033">
        <property type="entry name" value="Histone-lysine N-methyltransferase, H3 lysine-79 specific"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF0">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU271113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT98916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="26659" checksum="B763C68321796B7A" modified="2013-05-29" version="1">MPGLHHEVVRHICEEVHHRTVGPHARDLNQYKAWSNKVYGEFSTSFVTELAYVTEMKPTSKVLDLGSGTSHALLQACLLSGCTSLGIELREDASAIADEQVAECEKRARMWGVSWGGGVTAIQGDFTDSAEVRKWISEADVIICNNYAFKSDLNNTLRQMWMDCKLGCKIVSLLPFKSKNFKVRLDSMDDPQSILAVEERKYRKGAVSWTHEAGKYYLHTCDRTELWEFARKHGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZD6</accession>
    <name>M5FZD6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">NAD(P) transhydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="23">Nicotinamide nucleotide transhydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">DACRYDRAFT_67068</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">In the C-terminal section; belongs to the PNT beta subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628122.1">
        <property type="nucleotide sequence ID" value="XM_040775835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZD6"/>
    <dbReference type="STRING" id="1858805.M5FZD6"/>
    <dbReference type="GeneID" id="63690897"/>
    <dbReference type="HOGENOM" id="CLU_003376_0_0_1"/>
    <dbReference type="OMA" id="EQCREVD"/>
    <dbReference type="OrthoDB" id="37244at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05304">
        <property type="entry name" value="Rubrum_tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000028">
        <property type="entry name" value="NAD(P) transhydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000002">
        <property type="entry name" value="NAD(P) transhydrogenase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026255">
        <property type="entry name" value="NADP_transhyd_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00561">
        <property type="entry name" value="pntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006942">
        <property type="entry name" value="PRK09424.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="18 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="13" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 24" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="579"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="658"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="719"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="755"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="780"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="810"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="838"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="26">
        <location>
            <begin position="54"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="25">
        <location>
            <begin position="202"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
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            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00054910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00061558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00074145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00079255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EJU01225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1063" mass="110811" checksum="7F56CC6F5A734CD7" modified="2013-05-29" version="1">MSALLCLRATQGTRPFHSKQAAALLLRAFHRSPIARAEETATPAGTPYSKLTVGVALETFPDERRVALTPQNAAALLKKGFSRVLVETGAGREAQFLDDQYKAAGATIVNKDDLYAGTDILLKVRPPLFGQTSTEVDKMKKDSTLVSFLYPGQNKQLIEALGKKEINALAMECIPRVSRAQVFDALSSMANIAGYKAVLEAANHFGRFLTGQTTAAGKIPPCKVLVIGAGVAGLSAIATARRMGAIVRGFDTRPVAREQVESLGAEFLEVTGIQEDGSGAGGYAKVMSKEFIEKEMELFMDQCRNNVDIIITTALIPGKPAPKLITKEMVAAMKQGSVIVDLVAEAGGNCELTQAGKVVQNNGVTIIGYTDLPSRLPTQSSTLYSNNITKFLLSISSTPGYFNIDHSDDVVRGALILEKGKLMWPPPPSAVAAPPPLPPKIEAKEEVTAITPWQKASREVALTTAGVGGVLALGKATGSAFMDNFFTFGLASLIGYRVVWGVAPALHSPLMSVTNAISGMVAVGGLFVMGGGYFPGTIPQALGALSVALAFVNIFGGFVVTQRMLDMFKRPTDPPEYPWLNFVPAAVFTGGFITSAATGMSGLVQAGYLASSVLCIGALSGLSSQTTARQGNAFGILGVGSGVLASLGAVGFATPVLAQFGAVAGIGAVVGTWIGRRITGTDLPQTVAALHSVVGLAAVLTSIGSVLGNLTHVSTLHMVTAYLGVLIGGITFTGSIVAFLKLAGKMSSKPLVFPGRHLVNGGMLAANLGLMVPFLSAGPAAPLIAAGCLLGNTVLSFIKGWTLTAAVGGADMPVCITVLNSYSGFALVAEGLMLENPLLTTVGSLIGVSGAILSYIMCRAMNRSITNVLFGGIPPMPAHADGPKITGTVTATTVEEVAEVLKNAESVIITPGYGMAVAKAQFTIAEITKDLAAMGVKVRFGVHPVAGRMPGQLNVLLAEASVPYDVVLEMDDINEDFADTDVVLVIGANDTVNPIALEPGSSIAGMPVLHVWKAKHVIVMKRSMSSGYADVPNPLFYMPNTRMLFGDAKTTTDAIKKAIEEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZG1</accession>
    <name>M5FZG1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitobiosyldiphosphodolichol beta-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.142</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_82809</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.142" evidence="3"/>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625854.1">
        <property type="nucleotide sequence ID" value="XM_040776594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZG1"/>
    <dbReference type="STRING" id="1858805.M5FZG1"/>
    <dbReference type="GeneID" id="63691656"/>
    <dbReference type="HOGENOM" id="CLU_012079_1_1_1"/>
    <dbReference type="OMA" id="CWLCARI"/>
    <dbReference type="OrthoDB" id="614844at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004578">
        <property type="term" value="F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026051">
        <property type="entry name" value="ALG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036">
        <property type="entry name" value="BETA1,4 MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036:SF0">
        <property type="entry name" value="CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="456" mass="50655" checksum="73BC5890F03B8324" modified="2013-05-29" version="1">MYHAESFAAMGWETYIVGYKGAKLIPSLLQVPHVRELYLPQPPAFIANLPRLLFLLWAPYKILFQALTVLSTLLGELPYAPEFILVQNPPSIPTLALVQLCARLTGSKLVIDWHNLGYSILALRLGASNPVVGLAKMFEKTFGRKAYAHLFVTHAMKGVLVRDWKLLGIKAVLHDRPPSHFHACEPTEIHDLFSRLDLRPAGEDFLPPSSPPLSTPFTRLRDLPPSSLSPAFAATLPDRREDRPALVVSSTSWTADEDFAVLLNAMAFYEKRARAVNSPPKENPQKGDKHDRLPKMLVIVTGKGPLREKFTQDIDECQKLWQWVRCVPMWLEAADYPLLLGSADLGVSLHLSSSKLDLPMKIVDMFGCGLPVCALGFDCLSELVGEGNGRVFKDAGGLAAECETVLKGFPHAPELEKLKQGLVLQKSPTAGEKWNTWAEEWDRVVKPIVTHRPGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZM1</accession>
    <name>M5FZM1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Helicase SWR1</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Helicase swr1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">DACRYDRAFT_25392</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623850.1">
        <property type="nucleotide sequence ID" value="XM_040774142.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5FZM1"/>
    <dbReference type="GeneID" id="63689204"/>
    <dbReference type="HOGENOM" id="CLU_000315_24_3_1"/>
    <dbReference type="OMA" id="AFQQWFG"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000051">
        <property type="entry name" value="Helicase SWR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSA" evidence="22">
        <location>
            <begin position="329"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="845"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="21">
        <location>
            <begin position="1378"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="143"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="456"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="660"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="782"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="660"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00040599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00074297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EJT96952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1619" mass="183773" checksum="30D3567DE498C1C5" modified="2013-05-29" version="1">MSGRNIRQPSSQTASSAQTKRRNSSRLQPTRADAPSPDFNAFLYSHHHLSSNPIENRRQVLIRERQNNLRIVFGEHDALVREAFHLENFVTMVGYEPEDAKQDKSSVYHEFESQFNLLNAIPSNPPRSTRHRASEGAELLAALTSMSSSRSSKSNGTAAELESSELSAPTGLTNNRGTHARHATDDFANGHELRRLSSRHQPHDLALSSPLSNHALSTSSEGPTLPLVRPLKRPRPIELNSTFAKVKRIRFTVKLPPAEYTNPDQKPSRPKFARSVDDYLDSYFTVGDEEVTVSELEASASRDAILYDRITALQAKGRLRAQPERPVAAPVSFEAKRPLSHWDVVISHAAIQMKRMQDELRAKQNVTRRISRAVAAHFDRIAQTEERERLGEEKRLRALAKFIVREVIKKWREAINHVREVRSVLEKEELARQGKKQLNAILEQSTQVLEAQQMDLTRGGRSGSASTPASWTDSSSQSEEGTNYGSDVDGDTDDEDTNEEVQSDGEMAEDHSPEEPHEQLEDTDGDGQYVDDETDHSIPEHVEGPALARVHTNHLQAGDGFISPSTEMVNSDAKTIVLKSHGWRRPPRRSDEPTLANLDTFEEWKQTHFQNDGQQNIATANLANPLNGRVQAEPVSPALVLHEEDDGDFNMEVSSDIEEQDREMEHAMEEEDNKNDDSDEEIGGLQQDADIPIEALLRQYGYTVLEDDVNSDHCGDFDTAEGQMTALTAENGKMFLLEDRTVEALSSTGSSTVKQVVPEDSVASESSTTVHTVHFHEEAHPAALASMGDRTDAAEESISAKDEEMEEASEAESSIDKAVDGRIRPPFLLRGALRPYQHAGLEWLVSLYNNGLNGILADEMGLGKTIQTIALLAHLACDRGIWGPHLIIVPTSVLLNWEMEFKRFLPGFKILTYYGSIKERREKRHGWNTEFHFNVCITSYQLVLADQHIFRRKQWRYMILDEAHNIKNFRSQRWQTLLGFHSQRRLLLTGTPLQNNLMELWSLLYFLMPSGLSEEFSAGTFAGQKQFAEWFSNPMDKAISNTDGAQLDDETLETVNKLHTLLRPYILRRMKSEVEKQLPAKYEHIVECRLSKRQRLLYDEFMQRASTRETLATGSFLSVVNLLMQLRKICNHPDLFEVRPILTSFAMGKSRSAIADFEIKELLIRRRMFAEEEFQPVDLKVTGLVFTHNENISAHACHDMCLLDATSKLPFIADLPEEPPPHDIVGMEAFNKHIEWQEREATRARWQHIGYLNSRRCTQHPVYGFELLRQVRKMHYQVVPLEEAELNRRFLLKKLDRVHAAVQSYHQRVCSLAKSIDQFAFVTPAAVALDLPRIALPGVQLEEHPDLAEPAFDTLHDVSVKLQIAFPEARLLQYDCGKLQELDVLLRERKAGNHRVLIFTQMTKVLDILEIFLNLHGYRYLRLDGATKIEQRQLVTERFNADARIFAFIASSRSGGVGINLTGADTVIFYDSDFNPAMDRQCEDRAHRIGQTRDVHIYRFITKHTIEENMLLTANHKRTLDDVVIRQGDFDWRRILVDDLQMEQALAQVEDQADAEAARIALNEEKEDAADFDDRISRTNVPFEDSGALGPEEEEDVGGTTIDYMVAFVEREWEYFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZP0</accession>
    <name>M5FZP0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_90643</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625929.1">
        <property type="nucleotide sequence ID" value="XM_040776961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZP0"/>
    <dbReference type="STRING" id="1858805.M5FZP0"/>
    <dbReference type="GeneID" id="63692023"/>
    <dbReference type="HOGENOM" id="CLU_073125_0_1_1"/>
    <dbReference type="OMA" id="ANRRSYY"/>
    <dbReference type="OrthoDB" id="2138173at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.109.10:FF:000001">
        <property type="entry name" value="Nitroreductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035:SF1">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="7">
        <location>
            <begin position="51"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT99031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="242" mass="27352" checksum="81B2C6F0ECE92381" modified="2013-05-29" version="1">MSHSSSPVTMFKAMIRRMSTKAGISEKEWFEKRPNMEPPAQPSQTFLQAVETRRSHYSIANSSPISDIRIVQVVQHAVTHVPSSWNSQSSRTIVLFGNEHAWLWDTVISALKRITSGSKFEAASGKVTASMKAGHGTVLFLEDDEVIRDLQQRFPTYKDDFSTWSEQTSGMVQFITWVALEEEGLGANLQHYNKLIDAEVRDHFKIPNSWRLVAQMPFGEPTAEPGEKAFQPIEPRVKVYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZR1</accession>
    <name>M5FZR1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_118335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625949.1">
        <property type="nucleotide sequence ID" value="XM_040770564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZR1"/>
    <dbReference type="GeneID" id="63685626"/>
    <dbReference type="HOGENOM" id="CLU_1129025_0_0_1"/>
    <dbReference type="OrthoDB" id="10353375at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="246" mass="29622" checksum="1DA08AD7315C8926" modified="2013-05-29" version="1">MWSTNTYLPPARGFSDPTKPVPNLPSAQDYKDDDILLFNLLANKPPTIEDLRKYKARDWDKLEHLESFVRMRKSQHVDELSVVHAARAKAFAELERQLFLATPSRDTSDSELLAAVEEEKAREKEVLDRRWRRIEQIVNETYWREVLEKEKKIEQIIADPQPKNYPPVRVPRSWDELKMYPEYMKLDLARLLYRHAENKLFKAQLRDSKWHKDKEVADFDTARDLYKKERVFKEYLERNYKVIRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZY3</accession>
    <name>M5FZY3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Small nuclear ribonucleo protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_99184</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630470.1">
        <property type="nucleotide sequence ID" value="XM_040777572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZY3"/>
    <dbReference type="STRING" id="1858805.M5FZY3"/>
    <dbReference type="GeneID" id="63692634"/>
    <dbReference type="HOGENOM" id="CLU_002242_0_1_1"/>
    <dbReference type="OMA" id="LVMNYVW"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000073">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000088">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000329">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="223"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="986"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="128"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU03576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1206" mass="134578" checksum="4C5EE088BF34B014" modified="2013-05-29" version="1">MRTLDAVMMAFKSKGEDVDNCGDWFKMSSPERQELQSYTAPKDVLEEFAAMAEEEDVDPFAETALKRQVLQRGSEYQRKGAERAMERGNEAIRADPFAQGAEGDGDSYKDAMRLQMLEREEERVRRAIVEKERKEKEEGKVAQDLDKTPPAELLALMRGDQTPPRLGMDLDKTPPKAQPAASSTRRKRRWDIKDDEETAVESDSTAVATGEWSEKALEEAAPPKKKRSRWDETPAEEAAVKAEETAPAAAAAPKRSRWDQTPVGLPPMTASGGLAPIIMPNYHALSEDKNNRYMSDDELDIVLPPSGYVIVTPPPGYERVAPPKNISNPLTGFQIQEEGSGATAAIAAALGPEAPTEIPGVGNLAFFKPEDATYFSKILKEEDETEMSVEELKERKIMRLLLKIKNGTPPVRKTALRQITDKAREFGAGPLFDKILPLLMERTLEDQERHLLVKVIDRVLYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLSKAAGLAHMISTMRPDIDHVDEYVRNTTARAFSVVASALGIPSLLPFLRAVCRSKKSWQARHTGIRIVQQIAIMMGCAVLPHLRNLVDCVAHGLEDDQQKVRTMTALALAALAEAAAPYGIESFDNVLKPLWIGIRQHRGKGLAAFLKAIGFIIPLMDPEYASYYTKEVTVILIREFQSSDEEMKKIVLKVVKQCAATEGVTPAYIKHDILPEFFRAFWVRRMALDKRNFKQVVETTVELAQKAGVAEIVGRIVNDLKDDSEPYRKMVMETITQVVAKLGASDIDEKLEEKLIDGIIYAFQEQTSEDQIMLDGFGTVVNALGVRVKKYLTQIVSTVLWRLNNKSAKVRQQAADLTTRLAVVIKQCGEDALLSKLGLVLFEQLGEEYPDTLGSIIAAEGAIANVVGMTHMNPPVKDLLPRMTPILRNRHEKVQEASINLIGRIADRGAEFVPAREWMRICFELLDLLKAHKKGIRRAAVNSFGYIAKSLGPQDVLQVLLTNLRVQERQSRVCSTVAIAIVAETCGPFTCIPAILNEYRTAELNVRTGCLKALAFVFEYVGPQSAFYVDSVVTMLEDALTDRDLVHRQTASTIVKHLALGVAGLGCEDSMMHLMNLVWPNCFETSPHVIGAVMDAIEAMRVSLGPGILLSYTLQGLFHPARKVREVYWRVYNALYLGAQDSMVPFYPDLAELSDKRNTYDRHALQMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0A0</accession>
    <name>M5G0A0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RhoGAP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_49664</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630570.1">
        <property type="nucleotide sequence ID" value="XM_040774924.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5G0A0"/>
    <dbReference type="GeneID" id="63689986"/>
    <dbReference type="HOGENOM" id="CLU_001321_2_1_1"/>
    <dbReference type="OMA" id="QCSAKFF"/>
    <dbReference type="OrthoDB" id="20689at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09391">
        <property type="entry name" value="LIM1_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09392">
        <property type="entry name" value="LIM2_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000058">
        <property type="entry name" value="Rho GTPase activator Lrg11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF10">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="112"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="961"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="715"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1207"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1288"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="755"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1258"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1325"/>
            <end position="1346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1352" mass="151150" checksum="47F411CDCF7D585C" modified="2013-05-29" version="1">MSPHTRPADVQEELEHAHQRTGSPGAAPQAQYDPHGHQTRVQFPPPNIRHKSERASSPTGSEASREPDDGHPPYVQAQVPPESQPRPRPPSSSGSDGSVPNRTVTPSTLQQPICHVCNLVMTGQFVRALGNVYHLDCFRCRDCDRPVAQKFFPIEGSDGRQQPLCERDYFRRLNLICGKCGEALRGSYITACNKKFHVEHFTCSVCPTLFGQSDSYYEHGGDVYCHFHYSTRFATKCVGCGSAILKQFVEINRNQRNECWHPECYMIHRFWNVKMTSRLLPSEVPPLPPDPNPDGSPPELQPTYQKEEATETAVSLRNKQRQMEQQVYRIWNTLSQFEESSATCIQNMLNNVANGHWLEAIRFAEKFILHVEVLFAVVDDLEAQFIKFNAKGMSHIREARMLCRKTVDLFTLLSRTEHTVDRRMRFTEELLAVVTGLAHYLKILIRIALTGSLKLEREYEDRSAGSNMLDKLQTLVREGANPSARRATRATGSGATPGTQGVVYGYKCLAPEYAGESPFSPNATDSQQMDPPSDLCVECSQTVEEDCVRLGTYTRWHSQCLKCERCGRNALASPKKESAVTSGEEGAPSKISSSRRPPALVQEFVYRPGQKKPKQLGEPQPAVILCITDREPDCQVGFETVTKLEQFAFLLNVALRRLYDLLRRKGWMALPSSSAASDAFSETKSLSESYRDSTEIMRLKSVHLDRKLSATARLPKRSTIVESPSGRIAQPTDATFHSSVPPRSQQPAELSQQRPQPPVSHRPQPQPHAPIPTRVAPPPAVLAQQQLPQPPSLPAGRLQSPSPGPVTVGPDGSSIIRPNFARNNTSVRIIAEADDSSTAVESSTGRVATIHEAPNENDGFNVEEDAITLADIPHMMEAEQAREQQRSLPRQAGKPMISELSSLELMILKHFSALVLNKSPLRDQFDLDEILDLIEVKNKGLFTKLFKGEKKNVKKKGAFGVPLELLVEKEGVDSLLGASRTALRVPSFIDDVVSAMKQMDMSVEGVFRKNGNIRRLKELADHIDRDPSTVDLTTESPVQLAALLKKFLGDLPEPLLTFKLHKLFTATQKFSNADDRRRYMHLVSMMLPKSHRDTAEVLFVFLKWVASFSHVDSETGSKMDLQNLATVIAPTILSARSRDPAKDEIFLAIRVVAHILELQDELYAVPDEFIPILHDMDYFMSCADLPRKEILKKCELYWKLKHPKPGANGLPPSNSYRDGLARPDQYRGESQTRLLTRRSDPAMSNRPGPPHVNGTRTPQALPPQSQQAPANYPNEVMSQSIGSWVDINAPEGVYGSPPNGQPMQQSRNPIYQPVPQQARPPDQRWIQQERPSTGSRPTSYIRTEQYPQGYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0B0</accession>
    <name>M5G0B0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_109982</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626159.1">
        <property type="nucleotide sequence ID" value="XM_040768979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0B0"/>
    <dbReference type="GeneID" id="63684041"/>
    <dbReference type="HOGENOM" id="CLU_023630_1_1_1"/>
    <dbReference type="OMA" id="FQLEHRC"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56469" checksum="5FD7BE5A6C148B53" modified="2013-05-29" version="1">MPDLDAETEVYGMDGTKLKPLDTVYTFDQLIDHSNPSLGTFKQRYYFTYQYYLPGGPVVMMTPGENSVDGFYSYLTNGSMVGQIAQQQNGAAIILEHRFYGKSNPYPDLSVKSYQVHSIDQAVNDLVYFSQNVKLAMPGGNQIRSQRNAWILLGGSYSGALTAWTVNSNPDAFWAGYASSAVVQAINDGWMYFEPIRTHMPWNCSADWQALIGHFDKIAFNGTKEEQQSLKTQLGFPNVTYLDDVASALRDPIFMWQDMDPSSGPGEPFYKFCDALETDGNGKVSGPQGFGLNSTIKNFAAWVSTWNAESCGEDDQDACYGSRDPTNPAYSNTTIDQDSRSWQWTTCNFAGWWEVSAPNHYPSLVSRLITPKYDERDLCQNFFPEAYPTLHSANVSYVNNAYGGWHMNADRLIFLNGNRDPWKFATVSSDYINRTSTPNQPITVSDGFHCSDLLTANGEADNTIYKAQQLVLQYMEKWMDDWYTAHPSYPNPTGSALKKKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0D3</accession>
    <name>M5G0D3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626189.1">
        <property type="nucleotide sequence ID" value="XM_040773436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0D3"/>
    <dbReference type="GeneID" id="63688498"/>
    <dbReference type="HOGENOM" id="CLU_2812289_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT99291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="67" mass="7319" checksum="1CCA875A030229C3" modified="2013-05-29" version="1">MWAVSCWGFGGDPLGIEGAFPFSYLPPISVFHLPSPDSTPSHLLNNHTPSVPSVIVTATVRTTREYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5G1M2</accession>
    <name>M5G1M2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631010.1">
        <property type="nucleotide sequence ID" value="XM_040772064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1M2"/>
    <dbReference type="GeneID" id="63687126"/>
    <dbReference type="HOGENOM" id="CLU_2454696_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="89" mass="9671" checksum="18909235C360A83F" modified="2013-05-29" version="1">MIGKPAMPGDRLTFSEIGTGTGTGTGTVKLLVGLSATSIPVQLHHNPPHFDQSARTPKSAHHQHTQQRYVRLPDRCICIWSTSCDPVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G208</accession>
    <name>M5G208_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_40663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631115.1">
        <property type="nucleotide sequence ID" value="XM_040774489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G208"/>
    <dbReference type="STRING" id="1858805.M5G208"/>
    <dbReference type="GeneID" id="63689551"/>
    <dbReference type="HOGENOM" id="CLU_004966_2_1_1"/>
    <dbReference type="OMA" id="NDANEWF"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU04221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18799" checksum="43270B781AA43973" modified="2013-05-29" version="1" fragment="single">FGRCRMHNEQLVVHPCGIVLPQATFYGSKGMSSVTPFLMSIFPTCKAMPEVLVFDNNCTLGQYLHFKETALVVDVFHYKMKHADNNVYCSTHCNLASFPELYDPASKTWMFNSLACKQTNAWICKYQGQLQEMSAIRFKFFLDEVIKVRNEVIIEGLEHRGFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2M8</accession>
    <name>M5G2M8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_116148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629364.1">
        <property type="nucleotide sequence ID" value="XM_040770146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2M8"/>
    <dbReference type="STRING" id="1858805.M5G2M8"/>
    <dbReference type="GeneID" id="63685208"/>
    <dbReference type="HOGENOM" id="CLU_037525_0_0_1"/>
    <dbReference type="OMA" id="DWTQISI"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="220"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="302"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="379"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="417" mass="44338" checksum="8F4C3457A3D3EFA3" modified="2013-05-29" version="1">MSHIRRNSSVRFPPSPASLRSPSLPLADLPPSPQQPSSKFQEYLVSSPLRAIHLIDEPAVVVSGDAAVEDACAELLKAGPGACLVVQSSDAEGVHQDGLFDYADANSFLLLGLNARSLSSPTDPRVSQIILASRQGVVPIRLACNISQKNPMEVREEDASLETLLQIYSTGTHRVVIQPQPPTQPPKGLATDLSLISHLLHTPDPSVHSLLSLPLQSLLPDPPNPVIATSTDSTILDAMTLMDSEGVNSVAVLDANGNLHSAVSVTDIGRLVIPSLSKDVLSTKLGEFVQRIKWSAGETDGRDHFPVYSVLTSSTLEYMMEKLVATKAHRLFLVDDPLVPTSPSRYGNLRGVVSVVDILSIFARLAGLPDVDPFHLRRKRRTSSTSSLSSTHSRSSLGLLGTGGSSVTSLGEGGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2S3</accession>
    <name>M5G2S3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_99424</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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            <begin position="23"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="311"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="778"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="969"/>
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        </location>
    </feature>
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            <begin position="1037"/>
            <end position="1063"/>
        </location>
    </feature>
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        <location>
            <begin position="1280"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
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            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
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        <location>
            <begin position="778"/>
            <end position="790"/>
        </location>
    </feature>
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            <begin position="791"/>
            <end position="808"/>
        </location>
    </feature>
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            <begin position="809"/>
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    </feature>
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    </feature>
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            <begin position="969"/>
            <end position="984"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU02994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5G376</accession>
    <name>M5G376_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_81228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040776499.1"/>
    </dbReference>
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    <dbReference type="STRING" id="1858805.M5G376"/>
    <dbReference type="GeneID" id="63691561"/>
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    <dbReference type="OMA" id="HERWTIC"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF54">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="76"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="336" mass="39050" checksum="03878604509032ED" modified="2013-05-29" version="1">MFTSPSSLDLPTGPRQIFEKSTFFLRNPRAQLPTPAQVRAECKAQGGNYGSARPLPVRFPHLGLIVKFGFVVSITEGQCLLWLKQLGVVRVPEVYGWTTDRVGYNLEVFLYLELIPAVSLKDRWRWLSRSNKEHIARELRVIMDKVHSIPPEPGEVYIGSIGKQPVQEDIFASYTEAKPGPFTSLSSFHEYLLCYFRQPPQWVDPDRHLLPDDVPIQFTHSDLHMGNILVSPPLPWSKESLWMAWQEWSRNRWSLIWVWRALWWGTWRRMECGEPRVVAILDWQQSGWLPSYWEYCKAMWTADFQPRSWGNKYLPMILDKNDVFCVWGDIAAAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3C3</accession>
    <name>M5G3C3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transglutaminase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_75589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631600.1">
        <property type="nucleotide sequence ID" value="XM_040776144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3C3"/>
    <dbReference type="STRING" id="1858805.M5G3C3"/>
    <dbReference type="GeneID" id="63691206"/>
    <dbReference type="HOGENOM" id="CLU_031058_0_1_1"/>
    <dbReference type="OMA" id="AWDKPRL"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="5">
        <location>
            <begin position="197"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="369" mass="42660" checksum="5C22E11C62798973" modified="2013-05-29" version="1">MDEIVERLSAIAILHYERRSHQTHVPTQEEVLCIQEIATQVFRPPTSDASSQPEPPLLLAPSAAFREFEELVWGLNRNMDVYEKHDLLDKAMDEIPIQELHEKAEQLSAQSHKNHSSLAFEDALAEPLVQWFKHTYMRWINSFPCPICSGPTTVIGATPPTPEERVGRANRVELHKCQTPNCGGLHRFPRYNDPAMLMKTREGRCGEWANLFTLFLRAVGLRARYIWNREDHVWNEYFSPTEQRWVHIDSCEAARDKPTLYERGWGKKMSYIFAFSVEGALDVSRGYTLNWPAMEERRNWVPIDELQRVMQSITSTRRASLSSNQRAHLEAEDRVENARLQRGPDWTPSPEQGRQSGSTEWTHRRGEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3F9</accession>
    <name>M5G3F9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_118609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625195.1">
        <property type="nucleotide sequence ID" value="XM_040770619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3F9"/>
    <dbReference type="STRING" id="1858805.M5G3F9"/>
    <dbReference type="GeneID" id="63685681"/>
    <dbReference type="HOGENOM" id="CLU_041217_23_1_1"/>
    <dbReference type="OMA" id="ANGVMQY"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001072">
        <property type="entry name" value="Rab family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="222" mass="24434" checksum="EA4EC477EF6FA44A" modified="2013-05-29" version="1">MSDLTWQFIIKFIIVGDAGVGKSSILIRFTDSRFLANPDPTLGVEFGSKLVHLADEDKTIKVQIWDTAGAEQFRSITRSYYRGAAGALLVYDATSRTSFNNAKSWLQDVREHADPNLTCILVANKLDLLQEGEEGDRRRAVTKEEAAAWANEEGLLFLEGSAKTGENIEEAFESAVRDILDKIKRGVFDHHKPSGIKPARSAPGSTGLSLETEEKPPGYCCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3J7</accession>
    <name>M5G3J7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630143.1">
        <property type="nucleotide sequence ID" value="XM_040772419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3J7"/>
    <dbReference type="STRING" id="1858805.M5G3J7"/>
    <dbReference type="GeneID" id="63687481"/>
    <dbReference type="HOGENOM" id="CLU_076803_0_0_1"/>
    <dbReference type="OMA" id="CEASNCP"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="319" mass="35888" checksum="1082C6C1EAFB072B" modified="2013-05-29" version="1">MLGAPNTILCEPFARYAARLCQTSDPEKYPDGFAACVQLLMQKASIIDAGRDEEDDRRKRLEPGMQQILKCELEDIQDHHSESGAEGHSRVTLSKFGHISADILVVEYKSEVGAGPAEPSFQVQLTARKGWAQETNALLCEASNCPVLLITLIGPFLQVSGVVFQPAASVNQFTDNLSLTLDTDDFQRIDRLCHVLWCTQQCAEDLQTYYSELEPPAENHAISVLPYMPYSRRCGDYEIRYVSHLENTRHQQPMYMAKATGSDGQETEVVVKFTRRYSCLCTKRWRELGSLLRCLRSSGLQEGRSSWVSSPALHYGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3X1</accession>
    <name>M5G3X1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_21558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630268.1">
        <property type="nucleotide sequence ID" value="XM_040772447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3X1"/>
    <dbReference type="STRING" id="1858805.M5G3X1"/>
    <dbReference type="GeneID" id="63687509"/>
    <dbReference type="HOGENOM" id="CLU_029499_3_0_1"/>
    <dbReference type="OMA" id="MPVPNWW"/>
    <dbReference type="OrthoDB" id="285674at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03356">
        <property type="entry name" value="LbH_G1P_AT_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06428">
        <property type="entry name" value="M1P_guanylylT_A_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="7">
        <location>
            <begin position="284"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="409" mass="45078" checksum="A65BC2807D6CEE0C" modified="2013-05-29" version="1">MSVSSKAVVLIGGPSKGTRMRPLTLDTPKPLFPIAGRPLMWHHIRALSMVAGLTEVFLIGFYEDAVFAPFLKDVSREFKNLSVKYMREYQALGTAGGLYHFRDTILRGNPGQIFVLHVDICCSFPLKELRDFHGTHRGLVSMLGVRVPTETALKYGCIVPDPRTKQVLHYVEKPEGFISDLINGGVYLLEAQGFFEAIRVAMVRKSQQQAEDPYMYQDDLLRLEQDVIVPLCDTKKVFVYETPDFWRQIKSAGSALPATALYLNQYHTTNPEMLAKPTPSGPEIVEPVHIDATAQVDPSAKIGPSVSIGPGVVIGAGVRVKESIILDNVTVEKNAIVSNSIIAADCRIGPWARIEGEPLKPTSVEDSSTKETITILANNVNVARDVLVRCCIVLPQKTLTSNCHNEVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5G411</accession>
    <name>M5G411_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630308.1">
        <property type="nucleotide sequence ID" value="XM_040772458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G411"/>
    <dbReference type="GeneID" id="63687520"/>
    <dbReference type="HOGENOM" id="CLU_1384120_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="197" mass="22149" checksum="BDEA921127F75B9A" modified="2013-05-29" version="1">MAAADGADASIVAAPVVDKGEREKFLRKLTNKDSLGGLSTNFLIRYPDFLGCELRELSTGDILQMLRIIIEVKKDERKLSSALTQTSEYHRRALLKRHSKHYLTILICGIYTIIWTRSLPSAEVVIDSRDVKTVLRFIMYTTNGEDVQSALPTHHAVALPIEDDEFMPDEDSDEDSDEGESGSGSEEYEYETEEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G458</accession>
    <name>M5G458_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Amine oxidase</fullName>
            <ecNumber evidence="14">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">DACRYDRAFT_76109</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="13">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="13 14">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="14"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631945.1">
        <property type="nucleotide sequence ID" value="XM_040776183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G458"/>
    <dbReference type="STRING" id="1858805.M5G458"/>
    <dbReference type="GeneID" id="63691245"/>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_1"/>
    <dbReference type="OMA" id="RYWQNYF"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000006">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 14" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="17">
        <location>
            <begin position="146"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="16">
        <location>
            <begin position="294"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="745"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="747"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="762"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="12">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="13">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EJU05051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="778" mass="86448" checksum="8DF7369D6DE48DC9" modified="2013-05-29" version="1">MTPSANIIPVSPVNGTTTATTDGHNPVKAPAKALKPHPLDPLSPEEISAVSLALRHHIASNTPVKAVKFTNAYVLQPPKRDVLAYLGIPLETGKEPEPAPESIPRRAEADFIDAVTGDVYVAQLTFVEGEFKVDDLTKLPEGTQSIITPEELCLCEYALRKDERVCKLAAEVGVTPDQLHADGWALGWDDRWPTKTRVQQCLLYARYGEHENIYCHPMDFFPVIDSNSFEVLAVDFAPHRLGGIQPSTRVPPLHAKLERERIPPPQTKHEYLPDLLEKNPNFKGMRDDVKPLYVVQPEGVSFTVRGRELEWQKWKMHVGFEPREGLVLNTITYNDDGMIRPIAYKVSCCEMVIPYGDPQFPHPRKFAFDVGEYGMGTVANELSLGCDCLGTICYLPGCFVGNNGEPIKIKHAVCIHEEDAGLLWKHTDCRAGGRAHSVRARKLVVSWVATVSNYEYIFYWNFFQDGMFELEIRLSGILNVYVLGEGEKQSRYTTQVAPRIDAQYHQHLFCMRMDPMIDGIKNSVMETDVVPSEFPTGSEQNFAGNGFYTKNTIIKHTGEGERQYSAENDRRWTIVNTSKPHYSSGQPAGYRIVTHSFPRLLAAPGSWVRKRAPFARSSLWVTRYAPGREWPAGKYVPQTRAAPEDSLEYWMKGDENLDQEDIIVWFTIGTNHIPRPEDWPVMPADHLKVVFRPQSFFQCNPALDVPSTSAVGSCYAFGTAAAPVPGTHAVAVTTEGEAVVEETAGHLNGGANGHGTNGNGTNGHRSNNNGTNGAACCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4G6</accession>
    <name>M5G4G6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_108774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627604.1">
        <property type="nucleotide sequence ID" value="XM_040768731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4G6"/>
    <dbReference type="STRING" id="1858805.M5G4G6"/>
    <dbReference type="GeneID" id="63683793"/>
    <dbReference type="HOGENOM" id="CLU_616802_0_0_1"/>
    <dbReference type="OMA" id="ITPYRIS"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="339"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU00707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="444" mass="47697" checksum="036336BEC89F6531" modified="2013-05-29" version="1">MAVIHDLHANLKRKPSELALERRAIPRATAFATPDGAQVLEVRAGPSTSSSHHLAITPGASPASPAPTPNASSGTGSSSRGTPVFVPVLATVFSVLGVLLFGFLLFLLCRRRKKTTSATKVEAQKREKWGARWRQRGQDSSDAGSPPFMGYMGPASSDRTSSPSFLSPNTGAQLVNAPTSPSGWGPFHITPYRISFAVRMPLKSQPSKQKQAAIVGPKDLVLPSKPSRFYDRRSPPGGSQVSIFTRPSYRSRRTEGTPPPSYNSRGTSGRTLATLATNGSRSTSGRTPPSLPPVVTGPALNLIPPAPQSGEELSPYQPIPSAVLTPFDQVVIFPTTNLPLPRKMVVVSTFTPALSDEMSIQVGQILKLVEEYDDGWCLVERKAVNGQKAEQGAVPRFCLDEIHPDEPGTGSFSVRSMATPLSTGPTKSPRRKGSLRRRMRYSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4I0</accession>
    <name>M5G4I0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_110552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625545.1">
        <property type="nucleotide sequence ID" value="XM_040769077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4I0"/>
    <dbReference type="STRING" id="1858805.M5G4I0"/>
    <dbReference type="GeneID" id="63684139"/>
    <dbReference type="HOGENOM" id="CLU_051542_1_1_1"/>
    <dbReference type="OMA" id="GRQIGTH"/>
    <dbReference type="OrthoDB" id="2094832at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32543" checksum="CB2E0C1F00BB0630" modified="2013-05-29" version="1">MAANTAGHPVAPTKFNPSPDDLLFLHKTTGIPTVPELKAHVLGIQHQALQVHPYPCIARFSFTSPTVARFVGYKKALLLERERKGALLLDIGCCFGADVRKAVQDGFPPAQIVASDLHPEFLELGHRLFRDDERTLPIKFLAGDVLDPSFLSLPPPTPPPPPPVPVGVQALTSLTQLHKRVSAIHASLFFHLFSHFQQAHLAHLLGSLLLPKPGSVIFGHQIASAIEGTGKERGRWAHSPKSWRRLWEETFLELGWEGDVSVSATMLPMKGERALLAQGLGIGEGIMFWCVELTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4N7</accession>
    <name>M5G4N7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_86362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632105.1">
        <property type="nucleotide sequence ID" value="XM_040776771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4N7"/>
    <dbReference type="STRING" id="1858805.M5G4N7"/>
    <dbReference type="GeneID" id="63691833"/>
    <dbReference type="HOGENOM" id="CLU_000960_27_0_1"/>
    <dbReference type="OMA" id="YLSWKWV"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="548"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="572" mass="60993" checksum="0E8D7CE7D6619396" modified="2013-05-29" version="1">MASPQLPPEESEKVAMEADDLPLPAHEIVDAHQEIPVRLLPMPDPTDTDWLQSSSIQALVIAIPSIQQSLSINSASPQWLVTAYALTSGCFLLLFGRLADIFGRKRIFLAGTIWWIAFTIACGFAKSGVGIIILRALSGMGGAAVVPSAVGILAHTFPLSQARTVAFATFQAGAPTGGALGSIIGGLTTQYAPIGWRAIFFVSAGIGGVVFVLVWLAFPNHRGHYEDKRVDWLGAALITSSLILLMFCLGQGEIAPQGWRTPYIIALLILAALLFAAFVGWEHYVETRLTLPPLIRLNIFKRGQGKLAAILLVAFLIMGAFSSWQYWATLYYQDYKQFAPIDTTIRFIPMQIVGISINVLFALVAAHVSGYVLIVVGCCGTAIACLLFAIIDPNDSYWAYGFPAAVLDVFGADTTMGGGALFVAKVALLEEQSLAGGVFNTIITLGVSFTTTVTTIVYDTAVREEMSSMGLTLNADGSNASPDAALFGYQRAQWACFGFAAGAAMVALVLLRGIGVIGVKAVQNAEVLAPDTAGETIAAKHEEHIAEPVASLCTAEETKSRPESQKSDRTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Q9</accession>
    <name>M5G4Q9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_110623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625620.1">
        <property type="nucleotide sequence ID" value="XM_040769091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Q9"/>
    <dbReference type="STRING" id="1858805.M5G4Q9"/>
    <dbReference type="GeneID" id="63684153"/>
    <dbReference type="HOGENOM" id="CLU_044614_3_0_1"/>
    <dbReference type="OMA" id="WISIVRT"/>
    <dbReference type="OrthoDB" id="3357408at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29565" checksum="A4B6DCB31FC7897E" modified="2013-05-29" version="1">MLGLTLSNVLDAFVYLGQADPIAFLEVPFYWKSLTLQILGLFICLFADAILIYRGWLIWGQSWTAIALPVVMFMTSIAVFIFIVVELTRTATYLPSDALKLYHGLDAFIVLTMVQNVTVTSMIAYRLWRMDAATATYRSFTGLLPIVWIMVESGLLYTATLLVFLVVNFVAPWVSVIMSAILCGTIGITFSSIIVRCGISSWKRSIRSDDESHNMQPIPINISRRTEVDVMKEANVSMGTRTASTDSLPKRDPASKDSKFGQYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5W6</accession>
    <name>M5G5W6_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_110469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626050.1">
        <property type="nucleotide sequence ID" value="XM_040769056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5W6"/>
    <dbReference type="GeneID" id="63684118"/>
    <dbReference type="HOGENOM" id="CLU_677966_0_0_1"/>
    <dbReference type="OrthoDB" id="3365157at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="406" mass="45557" checksum="7A65636959BD3B68" modified="2013-05-29" version="1">MTSASNIEDEGRVVPLFINGDKIVFRMEGGIVHQIRVDLTNTKTHPNFPPSTPYKKLKARIVKEWRSTRARSSKVNISILDNPPCTGSSHPIPRDRPHGKCRQQATEPGYRIHEDGTLSGKKLPALPAGRAYTLAYVNPPLLSEVWRPSEPRSSTKFEWRGPHRTSERPVSNPSVLGSKGKKRARMSDYFKCSHRKSNDTHGTKTGTRALPFNPSKKRKRRDVLSHMDRKSLTVRIRGTKLTMAPKTMEKYYDSSDSDSESEVEEPLACWSTTHMYPLTERYHTMYNCDHEEAKLRLCSISSADGLNIHDISLYPSIPSHISARLPEEARECIPTETEMTEMAILAALAAMEQSFTNTYDFPHSLGLEDSGRNGMTPLTSAFNHCSPLVRFGTNQHLLGASLVTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6B2</accession>
    <name>M5G6B2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_62461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632690.1">
        <property type="nucleotide sequence ID" value="XM_040775698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6B2"/>
    <dbReference type="STRING" id="1858805.M5G6B2"/>
    <dbReference type="GeneID" id="63690760"/>
    <dbReference type="HOGENOM" id="CLU_005230_0_0_1"/>
    <dbReference type="OMA" id="FYLWFFL"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="775"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="696"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU05796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="841" mass="95537" checksum="C74310DC2E5F50E5" modified="2013-05-29" version="1">MPGYPSLFRSAAMSYVQLYIPTEVAHDTIAELGELGMVEFKDLNPGVNAFQRAFVTEIRRFDEMARRVRFFESQLDTASISTRPLEDSAPIISVGPRAAQTFDELEVTLKEHEDRLVQMNESYAMLNTRSRELHEARHVLRETAVFFEKAESQEHDRRHSLDEPTQPLLASEEAEAGHYHHPDAATSSVGLTIDLEFVAGTIDRQRLPTFERVLWRVLRGNLYMNYTDIEEVFVDPQTGEETRKNVFIIFAHGAALLAKIRRVAESMGATLYPIDANSDKRREALIEVTSRLEDLNTVLYNTGATRRAELTKVAESLAVWRDVVRKEKMIYETLNLFSYEARRRGFVAEGWVPTRDITPVQLALRQAMEVSGTSAPAILQEMRTHKTPPTYHRTNKFTEGFQTIIDSYGIATYQEVNPGLYAVVTFPFLFAVMFGDLGHGFIIFMAALMMVIFERSMAKAPLDEIVATFFFGRYIILLMGAFAMYTGLMYNDIFSFSMHLWRPGWYWPPTNGTAQAVRLDRTYPFGVDPTWHGTDNGLVFTNSYKMKLSIILGVIHMTFAICLQLPNHLHFKKPLNIIAEFIPQILFLQSIFGYLVICIIFKWSVDWTKSPTSPPGLLNMLIYMFLSPGKINPNEQLFPGQGPLQVFLLFLALICVPWMLCLKPYMLWREQRKIKGQGYQGVQMGDGVSDVRQMHDDDDEEEGAGVPVAEDEEGEHEEGMSDIIIHQVIHTIEFCLGCISNTASYLRLWALSLAHAQLSEVLFNMTLRLSFGRPGIMGVVFVVIMFSVWFFGTVGILCVMEGLSAFLHALRLHWVEANGKHYMAGGYPFQPLSFARVEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6G5</accession>
    <name>M5G6G5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_23914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626255.1">
        <property type="nucleotide sequence ID" value="XM_040773460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6G5"/>
    <dbReference type="GeneID" id="63688522"/>
    <dbReference type="HOGENOM" id="CLU_1250639_0_0_1"/>
    <dbReference type="OrthoDB" id="3388414at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="221" mass="24628" checksum="D667F161794BD9C7" modified="2013-05-29" version="1">MSGNDINPSTWEKRKEKWSANRARQDKAHQEVLRIVAALDESICRGAAASGVSEEGLREVIFGTQNLARFRRKRAPNLKNVAVHLTKVDLQAKGLEFDLHLAKPDWELCLAQLQEDADAAASGRDVLKARRDAETQQIRVSRKAREGDQTATTWALWQEAHAFNVRTRGHIFGFTVKGSPLDYGAAQFFGDDVGEAFLRQVLGKSGEELAKEFEIFAIHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6S4</accession>
    <name>M5G6S4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_102916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU05956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632850.1">
        <property type="nucleotide sequence ID" value="XM_040767684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6S4"/>
    <dbReference type="GeneID" id="63682746"/>
    <dbReference type="HOGENOM" id="CLU_2960689_0_0_1"/>
    <dbReference type="OrthoDB" id="3332563at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="Carbohydrate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="7179" checksum="84CAF5C0DA6C0CF8" modified="2013-05-29" version="1">MPENRVAFVWERNKLYFPGDRVGHRGGRWECRKGHVGDWITEPEIGLYWDSYWKKIEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7A5</accession>
    <name>M5G7A5_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795869">
        <property type="protein sequence ID" value="EJT99647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626545.1">
        <property type="nucleotide sequence ID" value="XM_040768935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7A5"/>
    <dbReference type="STRING" id="1858805.M5G7A5"/>
    <dbReference type="GeneID" id="63683997"/>
    <dbReference type="HOGENOM" id="CLU_005049_5_0_1"/>
    <dbReference type="OMA" id="GWWVLEF"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="168"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="477" mass="52975" checksum="33A2EFFD91260D5F" modified="2013-05-29" version="1">MTTRTSQPATYGLLQTGDKHGQVVVEDVALTDSPTVGSPTAIHPLPPPKQLILCFDGTSDLFDSANTNVVRLVSYPKKDDSMHQQVYYQAGIGTYIKSGWMMPFMVHLAKVFDMAVAWDICNHIMGGYTFLMQNYALGDKISIFGFSRGAYTARALAGLLENREGWNMSDGFKHTFCNEVEVDFLGVWDTVASVGLFRSKDLPFTASDHHIRVFRHAISLDERRCRLKANQWQEPYAPPNSNAPDEPGTLHPHSRTRRTKRSTSPCPYGTLPPGQSLAGSVDIGGGSWSTDVSDVWFAGGHGDVGGGCAKNVDLCAASRIPLAWMVREIVLSNTGITFDEAALSLDGISLPSPEFGPSILVKNPDGELNTRRVLAEENWVENLDKRYAEDINAPVGDQLKQAFYWWMLEMLPFTYRVPKSKKGPGNWKLSPRLTQFGSPRTLQGEKIRMHVSVQSRMKNSDYSPKVKYGNAQIEWVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7F2</accession>
    <name>M5G7F2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_20320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631553.1">
        <property type="nucleotide sequence ID" value="XM_040771885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7F2"/>
    <dbReference type="GeneID" id="63686947"/>
    <dbReference type="HOGENOM" id="CLU_1038366_0_0_1"/>
    <dbReference type="OrthoDB" id="3366144at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067555" description="Extracellular membrane protein CFEM domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="26475" checksum="C0A0E00C368242BA" modified="2013-05-29" version="1">MHFLSSSILLLALAAVGAQARPQEVAVRGLSGHVDPRNKVRDSLISKRQTEQCTGACSGDTNTLNAMAACASSGSADPIGSGECICQQMALLSSGCETCILNEDQITPADWAQTCAQLSSLPPSVLSTAAGSTSTGSSSVCTSQCSSAGDASGVTALLSCSTEDTACLCSAASGLSSTCLSCVLTYANLTQSQMEQICSSGTIAGGPSGTSTAGNAANTSSNKASNTGGASSPSTSATHSGTAKVAFGIKGAFVACTFVFVGGLMTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7N1</accession>
    <name>M5G7N1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sucraseferredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633090.1">
        <property type="nucleotide sequence ID" value="XM_040771524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7N1"/>
    <dbReference type="STRING" id="1858805.M5G7N1"/>
    <dbReference type="GeneID" id="63686586"/>
    <dbReference type="HOGENOM" id="CLU_048934_1_0_1"/>
    <dbReference type="OMA" id="VICYINE"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF14">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44654" checksum="43196E2CFD8C758D" modified="2013-05-29" version="1">MSLFSATGLFKEEKEQDDISTDLDEKCVPFSLDACRFCAEPCDEDHLEYPAKLDVDQTPGMFGSVKPYARQIVISTGKTDWPREITEEEDSLAQHVAQVNAWRTLERQVNAASEAAHGAEKQLVNGLAKLSLDDGTTAVPTPTDAHPPILEPSPVNHDEHPKWDGVWQSQDPSASRLSILNGSHTASEDGMANVLIFPDYKMVRVEEGREGAETLWENALNPDLRLAGKGSEHESKSYLLPYSCVILLCSHKRRDNRCHIVAPKLLQAFTSQLEYEGWQVDHNIDENYDDWGDSLESITGLTQDEREMIVEKRLADPERRENKRVLILRSSHVGGHKYAGNVILAFPTRAMVWYGRVTPHEVASIVKNTITDGKVLPKLMRGGMNLSRKCGKRTLLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8A4</accession>
    <name>M5G8A4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MBOAT-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_47492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631888.1">
        <property type="nucleotide sequence ID" value="XM_040774759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8A4"/>
    <dbReference type="STRING" id="1858805.M5G8A4"/>
    <dbReference type="GeneID" id="63689821"/>
    <dbReference type="HOGENOM" id="CLU_021430_1_1_1"/>
    <dbReference type="OMA" id="GWHRSYN"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051085">
        <property type="entry name" value="MB_O-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285:SF18">
        <property type="entry name" value="PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU04994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="563" mass="65128" checksum="E1C1BD113D6D5695" modified="2013-05-29" version="1">MRATTQSGPAKHAHHSITELTVRVPASKPPANYIPGPPRWRTPEFIFYITCFVFIVPWMPYIPWAYLNTPQNPNYPSFRPLLSDSYIPGLLVDDSDAQYRSFRSNIPALLGLAGAYLLLRGAFARYLVPSQPQGRSHLTSFHLLSSFLLLSALHGTSIIKIYTLLLTNYCIVKALPPRSPILAVYTWAFCAVVLFANEIYEGYSFAALHPSLTPLDAWTGFYPRWHISFNITMLRIISFNLDWRWANFSQPGDTSSTLLDPKTRVTQPHTLASYTLGNYLAYILYPPLYIAGPIMTFNDYLHQVRSAPTPDTHLDYVKKYLYRFIFCLVTMEFVLHTMPVVAIKDSHAWQGNTPVELALIGFWNLIVVWLKLLIPWRFFRLWALADGIDPPENMVRCMANNYSALGFWRSWHRSYNLWIVRYIYIPVGGSERALLASLLVFTFVALWHDLSFRLLTWGWLVVIFLIPELAARQLFPYSKYGKNWWFRHICALGSAMNILMMMTANLVGFVLGTDGTEYLWWELISNWNGLVFMLFAIFCLFLGTQIMFEYREEELRQGIYRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8I2</accession>
    <name>M5G8I2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="12">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20996</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631369.1">
        <property type="nucleotide sequence ID" value="XM_040772185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8I2"/>
    <dbReference type="STRING" id="1858805.M5G8I2"/>
    <dbReference type="GeneID" id="63687247"/>
    <dbReference type="HOGENOM" id="CLU_125186_1_0_1"/>
    <dbReference type="OMA" id="VPPINCI"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000013">
        <property type="entry name" value="Small nuclear ribonucleoprotein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU04475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="93" mass="10634" checksum="4EBC510555C2A27B" modified="2013-05-29" version="1">MSGRQQRVMVQPINVIFKNLQQRVPVQIWLYDNVEMRIEGRIIGFDEFMNVVLDDASEVFVSEESKSPRSLGRILLKGDNITLIQPSSHSSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8N1</accession>
    <name>M5G8N1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_55071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
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                <person name="Martin F."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="137"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="164"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJU00128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32241" checksum="59DF5DC7A3570040" modified="2013-05-29" version="1">MSYFLSHRILADIGQEGCETAAQVAEEAIKAERLCPIALSVSVAGSWFIGVIYLLSLLFSVQSIASVQNTSYALPITQLIYDAVGRELAILLIVIILVAQWAAALTAWTASSRLFFALARDRAFPFQKTFMTLSQTGAPYAGVWLSVFVGCVIAAAYIGSAIAFNGILAAAAIGVLLSYSVPIFCRVFWPNTLDERGPFTLGRYSWTLNLLSLLFCLFSCVLFILPTSTPVTSLNMNYAILAIGAILILVALQYLIWGQWIFRGVVTTYGATSLAEGVDITGEEKGNYISVRGTISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8Y1</accession>
    <name>M5G8Y1_DACPD</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_15630</name>
    </gene>
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        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067671" evidence="2">
        <location>
            <begin position="26"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="175" mass="19721" checksum="DDBD0045B172443F" modified="2013-05-29" version="1">MPAEHRVLTILCMCSQHFMVAGVAAAKEEEVGHELSDMEEGKASKGDGNHWSNVIASALWQHAAAGLLVWDKFCGHADGFEDGWEAEAAREKAEKLKELKKSRSWGGWFWTGMMIVLRWLVWVLSHIFNSKEYNDAMVKHKYKWLAFTFVSIIAIACGVNPIDVLLKVINSWAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5G943</accession>
    <name>M5G943_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_109047</name>
    </gene>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627205.1">
        <property type="nucleotide sequence ID" value="XM_040768797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G943"/>
    <dbReference type="GeneID" id="63683859"/>
    <dbReference type="HOGENOM" id="CLU_146837_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU00308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="135" mass="16122" checksum="9E224B7EE374EF82" modified="2013-05-29" version="1">MSTTPLLLVTSQWKHDHPPFAMSYPSLKSMILQHKDLSREMDEPMEELEEVQQRWKEQQQQRLQEQDSRQVQQQLQKSLQLQQEQEQERQEKELWEEEDVFLEQEDSPKQDTIMDVEVAAIMEQEGPEQTSVVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G983</accession>
    <name>M5G983_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribophorin II C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_66539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629321.1">
        <property type="nucleotide sequence ID" value="XM_040775821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G983"/>
    <dbReference type="STRING" id="1858805.M5G983"/>
    <dbReference type="GeneID" id="63690883"/>
    <dbReference type="HOGENOM" id="CLU_051361_1_1_1"/>
    <dbReference type="OMA" id="VFFMYYT"/>
    <dbReference type="OrthoDB" id="432292at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="8">
        <location>
            <begin position="134"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU02427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="231" mass="25186" checksum="A4DB41C4F2FCAED4" modified="2013-05-29" version="1">MLTPNAPELPTLAVSAADTFKLSFTVEDEKGNAVVPVQSMLRLWDEESGEDTLLPFKVSLAGKGRFELNMRRPPPQLPPTPTKTPLNVSLVLASPPHAPVQLNLLHLQLPLSEPAAEHPEEHLYHLQPEIYHTFRPEEKVPPRIISLLGAGAVGAPWALLLILLASLRPSFSFATSPRLLLFLTTLTAFDGLLITYWIQLTLGQVLLYGSILGGITVITGVSALNARKFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9Z6</accession>
    <name>M5G9Z6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_23053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627565.1">
        <property type="nucleotide sequence ID" value="XM_040773070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9Z6"/>
    <dbReference type="GeneID" id="63688132"/>
    <dbReference type="HOGENOM" id="CLU_2066948_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067609" evidence="2">
        <location>
            <begin position="20"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="119" mass="12835" checksum="3423A931E4BD7BF8" modified="2013-05-29" version="1" fragment="single">MPSTKQLLFLAIAASTVLAAPMQMKKTEATINTDLTMTEAPSAASAPISGDGVVPPSPAKVVPPSAPTFSQRRKHDGAYRRQGRRGCVHKNCAHLTHRKKRMYKHSYQSLENGPASPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAC4</accession>
    <name>M5GAC4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-demethoxyubiquinone hydroxylase, mitochondrial</fullName>
            <shortName evidence="8">DMQ hydroxylase</shortName>
            <ecNumber evidence="8">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ubiquinone biosynthesis monooxygenase COQ7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ7</name>
        <name evidence="9" type="ORF">DACRYDRAFT_75155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="8">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the COQ7 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="8"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAC4"/>
    <dbReference type="STRING" id="1858805.M5GAC4"/>
    <dbReference type="HOGENOM" id="CLU_071892_0_0_1"/>
    <dbReference type="OMA" id="WSTAVMG"/>
    <dbReference type="OrthoDB" id="275371at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237:SF4">
        <property type="entry name" value="5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="COENZYME Q10 BIOSYNTHESIS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="223" mass="24555" checksum="4B2B281B37D47A79" modified="2013-05-29" version="1">MLPIRRLSPLLVRASRAAATTTTNLSSRYVNLQPSDPSTSTTPHLNAAERSQLGQIIRVDQAGEIAANWIYAGQMAVLGRDKKTRPLIQEMWDQEKKHLLVMDRLQAQHRVRPTILAPVAQIAGFGLGAVTALMGRDAAMACTEAVETVIGEHYDDQLKALESMPRHPSLSLLKDVIVELRDDELEHLGTAVENNSQRTPQHALLTTIVETGCKVAIELCKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAG7</accession>
    <name>M5GAG7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinyl-CoA:3-ketoacid-coenzyme A transferase</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_19881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate</text>
            <dbReference type="Rhea" id="RHEA:24564"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35973"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.8.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 3-oxoacid CoA-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632239.1">
        <property type="nucleotide sequence ID" value="XM_040771700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAG7"/>
    <dbReference type="STRING" id="1858805.M5GAG7"/>
    <dbReference type="GeneID" id="63686762"/>
    <dbReference type="HOGENOM" id="CLU_019942_1_1_1"/>
    <dbReference type="OMA" id="QITRAIC"/>
    <dbReference type="OrthoDB" id="1933379at2759"/>
    <dbReference type="UniPathway" id="UPA00929">
        <property type="reaction ID" value="UER00894"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:succinyl-CoA:3-oxo-acid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046952">
        <property type="term" value="P:ketone body catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1080.10:FF:000001">
        <property type="entry name" value="Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014388">
        <property type="entry name" value="3-oxoacid_CoA-transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF60">
        <property type="entry name" value="ACETATE COA-TRANSFERASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000858">
        <property type="entry name" value="SCOT-t"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="5-glutamyl coenzyme A thioester intermediate" evidence="4">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000858-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU05345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="516" mass="54898" checksum="68956E9AA9D5CEEB" modified="2013-05-29" version="1">MLSRLASRALVIVPRVRNYSSPLDLGVPKASKVWDNVDDAVKDVRSGEVLLSGGFGLCGTPDTLIEALSRRPQVRDLTAVSNNAGVGKRGLGLLLHTGQISKMIASYIGTNKHFESLYLAGKIGLELTPQGTIAERLRAHAAGIPAFYTPTGASTAVEHGTIPMRYKAGGFKEGVLDEGRKRESREFNGRKYIMETALAGDVAFVHVWKADESGNCVFRYTANNFSSVMARNAKLTIVEAEHIVPVGSLDPNAIHLPGIYVNRIVQASAPKQIEFKTLSPSTSAAASVSAAAVEEPTEAQKRRDRIVVRAAKELRNGDYVNLGVGMPTLVPGHLPPGVSVWLQSENGILGMGPYPTEETLDADIINAGKETVTLLPGASVFDSTESFAMIRGGHIDVSMLGAMQVSQNGDIANYMIPGKMVKGMGGAMDLVSNPDGTKVVVVMDHTAKDGSHKILAECDLPLTGARCVSKIITDLAVFEVDRKAGGLTLLELAEGATLDEVKAKTGCDFKIAPRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAU7</accession>
    <name>M5GAU7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632913.1">
        <property type="nucleotide sequence ID" value="XM_040767698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAU7"/>
    <dbReference type="GeneID" id="63682760"/>
    <dbReference type="HOGENOM" id="CLU_966503_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="31072" checksum="F95CCAB8A0583DE1" modified="2013-05-29" version="1">MGLGLELELELGLELELGLGLGLGLGLGLGLGLGLGLGLGMGAHYSLTPPPPPPSSQLHEPQLSTPAPDILDLAQFGVDGAGGGMGDGSKTRADRNVDLVRLVFQDSSILLRLPINLILDPDLNLKFFKSDATLSHPIQSQYLIQSQPPSRPISTSISSDLNLHLNLHLISSLPFPSLPLPQPDPISRANRLCTSLRSTRTHLPTHDACPVLASGVWRLAGMSLLHGRYTDVLRLRFSLFFFTFRSRLFSLRTNFPTNRVSEIAARCTLRPLIIRPSAAVSSRMSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB14</accession>
    <name>M5GB14_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Signal transducer</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_113661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632479.1">
        <property type="nucleotide sequence ID" value="XM_040769674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB14"/>
    <dbReference type="STRING" id="1858805.M5GB14"/>
    <dbReference type="GeneID" id="63684736"/>
    <dbReference type="HOGENOM" id="CLU_041217_21_2_1"/>
    <dbReference type="OMA" id="RTKRTCI"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032506">
        <property type="term" value="P:cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000678">
        <property type="entry name" value="Rho GTPase Rho4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU05585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23477" checksum="DEFDD7D0A335C8D7" modified="2013-05-29" version="1">MEYEHDQSSAGGFPGRRPDFKKKLVVVGDGGCGKTCLLIVYAENRFPEAYVPTVFENYVTTVPYEGKTVELALWDTAGQEEYDRLRPLSYPESDVILIVFAVDFPVSLANVQDKWYPEVAHFCETTPKILVGTKIDLRQDDHTRRMLAAQGQVPVTPDQGAGVAREIGAKYVECSAKTGQGVREVFNLALKESMRGKWGKVLKKRSGGCVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBK6</accession>
    <name>M5GBK6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_95041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628285.1">
        <property type="nucleotide sequence ID" value="XM_040777265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBK6"/>
    <dbReference type="STRING" id="1858805.M5GBK6"/>
    <dbReference type="GeneID" id="63692327"/>
    <dbReference type="HOGENOM" id="CLU_060788_1_0_1"/>
    <dbReference type="OMA" id="KCVEYDP"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="235" mass="26103" checksum="02A149C1A0C11C18" modified="2013-05-29" version="1">MAGYKSGVSFDTMGESTTELFSYTLQAKSENYERSRKTRIYLCAASPDESGQEALDWSVETLAQDGDELIVLRGFDTEDAGKQDLLRSQAHQLLLDILERNTQLSDGTRSLNVTVEFVAGRITDTIERLIALYRPDSLVVGTRARKGMKALGAALGAPGMGSVSRWCVSHSPVPVIVVRPERKVKKTLDKRRNDPKRAQDHWERVCRPTSGKYPAGPQALMPLRTLGNGYQIFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBN3</accession>
    <name>M5GBN3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BFR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_114869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AATF family.</text>
    </comment>
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        <property type="protein sequence ID" value="EJU03472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040769896.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="63684958"/>
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    <dbReference type="OMA" id="IVAYREH"/>
    <dbReference type="OrthoDB" id="5783963at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025160">
        <property type="entry name" value="AATF"/>
    </dbReference>
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        <property type="entry name" value="AATF/Bfr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012617">
        <property type="entry name" value="AATF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565">
        <property type="entry name" value="AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565:SF0">
        <property type="entry name" value="PROTEIN AATF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13339">
        <property type="entry name" value="AATF-Che1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRAUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="13"/>
            <end position="154"/>
        </location>
    </feature>
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            <begin position="272"/>
            <end position="356"/>
        </location>
    </feature>
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            <begin position="164"/>
            <end position="192"/>
        </location>
    </feature>
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        <location>
            <begin position="206"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
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            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08164"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU03472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="398" mass="43626" checksum="1D64C41AC06C47CE" modified="2013-05-29" version="1">MASPPPTNNSTTLKGNAITQQHTLHAALLSSRIALQKSVTIANRLPLPDAIVAYREHDAARDAVKELEEELRGLEEELASVQEVLCNLNGMNAEERPLKRKRPTVEVDEDEANDRASIEHDFATHLHTAHAYHSQLTAHTHAYTLQTLSKWSSKVLAVHPTLFQPQGQQGTGTSKFAQQMRDGNGTGAGETPRDVVQAVEMALANDGLKRKTRGRVHGERRIGAKHDALAGPSVGSQDRQAQETDVDGNEEGGNNTAQTSDEQETFSDGDFYGSLLREIIDSRRLPGTLSSEALTQLLPNRRSKQLKPRVDTKASKGRKIRYEVHDKLRRFMMPSMPVVVRGWGEAQVDELFGSLLGGGGETGLGPVEEGTHPTTLDKQHDKTQNDTDIPVGQLRVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCM7</accession>
    <name>M5GCM7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FIT family protein scs3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_63532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="EJU03962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_048143_2_0_1"/>
    <dbReference type="OMA" id="FTSWFFG"/>
    <dbReference type="OrthoDB" id="5579088at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034389">
        <property type="term" value="P:lipid droplet organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067624" description="FIT family protein scs3" evidence="9">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31157" checksum="F2824FA4E04B290A" modified="2013-05-29" version="1">MVTIFLGTLLSHLLSLTQSESLVALQTPSSATHSYFANKHNVFNLWFVKYAWGWTSFVFVLHWLAAPKGVRRPASWVRYTLATLAFLAFTAWFFGPAMMDRLRILSGGECVLPVPSPPASTGTSLSPPSAPYLLRVPYTLCYTRTPLSPSTHPELFAQPDIPAPPAGFRLTPRLRKGHDVSGHIFLLTLAVLFLVDEVALSWGLIWFARTRGVKPTWTHLWATVLVSALLVLWGWMVLITSVYFHTPEEKFSGFVIGLAAYAFSQIPLPFLDRWLDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDA2</accession>
    <name>M5GDA2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Allantoicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_20934</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the allantoicase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631281.1">
        <property type="nucleotide sequence ID" value="XM_040772151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDA2"/>
    <dbReference type="STRING" id="1858805.M5GDA2"/>
    <dbReference type="GeneID" id="63687213"/>
    <dbReference type="HOGENOM" id="CLU_018495_0_0_1"/>
    <dbReference type="OMA" id="SVYRCKP"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000059">
        <property type="entry name" value="Probable allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00813">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02961">
        <property type="entry name" value="allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="7">
        <location>
            <begin position="195"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="563" mass="60476" checksum="241A81C8A95DAC3D" modified="2013-05-29" version="1">MAHERVPLDKFQEVFGGTTELSSVALGGKVLSFSDEFFADASNLLKIEPSASLKGQFGPKGSLFDGWETRRHNPAHDWVVIALGAPGTVLGFDLDTAHFNGNEAPAASVHGFYSNDGKIPGPEDEDWVEILPKASLGPSSRHLFLLPSASGPYTHLKLSQYPDGGIARFRAYGSVSPLFPSNPQTPLDLAHVLSGGQVVSVSDAHFSRASNILLPGRGYDMRDGWETRRSREKGHTEWAVIRLGAPGYLTQAEVDTAFFIGNFPESVELLATSSDAVVPEEDATWTTILPRTKTGPNKQHFFKLENVEGQVYSHVKVVMHPDGGMKRVRLTGTRYVPGYPPPSLSRALPALPALPAPSEVRTIPAEPLTSAAFAPFGQVLQAWADPANAPEGIVHTLANGGTAVKYHRLAPITSSYPEGSAAFTGISVYRSTPAEGAVLGATWPVKVLERHPHTNQAFIPMGRTAHPEGEEALSPNGYYLVAVAETGEDDKPNLSTLKAFVASTSQGVMYNQNTWHHPMCVLGSAIDFACIETQIGTKSEGLDCEIVRYGEGEVGVAVQIPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDD4</accession>
    <name>M5GDD4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631341.1">
        <property type="nucleotide sequence ID" value="XM_040771038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDD4"/>
    <dbReference type="GeneID" id="63686100"/>
    <dbReference type="HOGENOM" id="CLU_060803_1_0_1"/>
    <dbReference type="OMA" id="NANVIIC"/>
    <dbReference type="OrthoDB" id="2562239at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="325" mass="35313" checksum="B86885C8A2E88D49" modified="2013-05-29" version="1">MSNSTGSFSFASFPALSGGLPTSPDEAPSIIFTIAYVALLPLAIWRTWTYRHPGTLLFTFVRLCLFISIRVATFALRAAEGASAQIPDNPVPSEGIFIAEQILLGVGFIVLVDLIVELLKSHIWRTDVQVVDETLFAQEGQRNVLQRIVRLMHVALIVSIALGIVAGTQYSDALTDPSTASNVKTLRTASTVIALVVSALCAIVSLFLMLQYSHLGQSRSVYLLVTSCIILVVPAYRLSTTLASQPSLEDLVSTDIRVKFYILQGLAEWLVAGLLVLVDVRVWFFAGGEKQMMLERGGLIPQGSAEEMRLGPVRGWGDRTPGSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDG2</accession>
    <name>M5GDG2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631401.1">
        <property type="nucleotide sequence ID" value="XM_040768108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDG2"/>
    <dbReference type="GeneID" id="63683170"/>
    <dbReference type="HOGENOM" id="CLU_122941_0_0_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="1">
        <location>
            <begin position="37"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="190" mass="20195" checksum="5149C337994818A2" modified="2013-05-29" version="1">MAIGERAMVDGHPVIVLLETANMAMDRTTIINLGMAMKFTGAVDWIPIGTQFMWTNPASTRFVQASSSSSATLTSSGSPHDDWLVLMNLLGAQGPDSAGNYLIPCGSQMTWNFAGTEGRNYTFSLIQDGTNDGTGFCQPAANDAGDTTNWITGVPFLDQYYIAFHYEANTVGFATRNLGASAASSAPFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE69</accession>
    <name>M5GE69_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_77875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629922.1">
        <property type="nucleotide sequence ID" value="XM_040776292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE69"/>
    <dbReference type="STRING" id="1858805.M5GE69"/>
    <dbReference type="GeneID" id="63691354"/>
    <dbReference type="HOGENOM" id="CLU_008455_8_0_1"/>
    <dbReference type="OMA" id="GNYFMRY"/>
    <dbReference type="OrthoDB" id="3066029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="68"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU03028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="537" mass="58001" checksum="A50DCA14024BBFED" modified="2013-05-29" version="1">MKKSPTSDGPSKRKSTDEDQRTLAEVPREGAAVGEGEVEDEPDPTLAHAQERKGDVYDRFSRRRKYAIVGIVAYSALLAPFASSSFLPSIPTISNDLSCSGDVINYTVAIYLVTIGVAPLAWAPYARFYGRKPIYLVSLPLFCVGSMGVALSQSLVQLIVTRILQGIGASSVLSVGAGSIGDIYRPTERGRAMGLMYGGALFGPALAPLVAGLLTQYVANGYGWRAMQWLLCAMGGLAAGLVLFLLPETAHSRGVVAELEKRKREGKRSRFVWVWLDPIKPVWLLRYKNVLVISIVSSVVLETTYAILVPLTYTIGPRYSITSVAVLGLLYLAPGVGNLIGSRVAGIQSDQAVKHSLRLRNGIFHPEDRLRATLIGSGIILPVTVLAYGIVVQFWMGPGGLAVALILIAASGFGLMTILAICNTYLVDSMQTRSTEVIAINNCLRYVACAASSSYCLPLTNAIGVAPMNAISSVLAWIGFALIAWTIRDGSKWREDQERKEGVKMMVEEGVKIENEGKGDRETEKEGNAEPEKKEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5GED3</accession>
    <name>M5GED3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_19863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632211.1">
        <property type="nucleotide sequence ID" value="XM_040771691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GED3"/>
    <dbReference type="GeneID" id="63686753"/>
    <dbReference type="HOGENOM" id="CLU_2263632_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11197" checksum="9E2C087E5BC4CBF3" modified="2013-05-29" version="1">MDAKFKAQAETHAARMVYTNRMLAASEEQNDALKARVAELESALRDADIKARRNDAIIDRLVAMDDPSNALPSPAQQTGDSPASSKSRPALTNRGFTRRAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEH0</accession>
    <name>M5GEH0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DACRYDRAFT_115454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630137.1">
        <property type="nucleotide sequence ID" value="XM_040770006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEH0"/>
    <dbReference type="STRING" id="1858805.M5GEH0"/>
    <dbReference type="GeneID" id="63685068"/>
    <dbReference type="HOGENOM" id="CLU_002893_0_0_1"/>
    <dbReference type="OMA" id="HQDFLMR"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="7">
        <location>
            <begin position="16"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="8">
        <location>
            <begin position="449"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="6">
        <location>
            <begin position="823"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EJU03243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1175" mass="128936" checksum="87216EAF95E6F05E" modified="2013-05-29" version="1">MRYVVTHHQPTAAVDSIRGDFTGSGSVQLVVAKVNRVELYNLSPEGLKRVCDLEIWGTITNIAEVKREDKQSHILVTTDHPDPYLLSLAYSPTPNPQFEVVHSASLKARAGRIAEYCQTSIVHPSGRVAVTSAYTGSLKVTVFGEDGKGKDIDVRIREQNLLSFAFLPLSTSSPFTLALLHIDQNGKRHLVTRSLKHVPEPGSTKSLASLDISEPTAHIPDINLDDEWEATSVVGVPPPRPGARAGVMVFGEGQARWYAVKEEGAPDPKGKRRSSTAGSPTQEKKGKSKPPRVEEAKVGLPWGRIAATCAIDEEKLLVSDEYGKLYLLALHRRQSEGPVVSIQREALGEISSPSSITHLTSSYFFVTSKCGDSQLISLTPSAICGTGNIAVLDTHLNLAPISDFVVTDPEKIGQQQIVTASGRMNTGSLRVVRSGVAFEELGLLEQVMNTRSIFPLKINFDAEYHLYLVTSSLHRTTLYSMRGDDSSPQFEEVDESEARGIVRQVPTLAAGNIREDDIFVQVTAGSVVAIDLITWEQRSIWKPHVEIVCAAVNGQRVVAGLKGGYLVHLIPQRDQFIVANDWKSPGSWGLTEISCIALDPTLSAELGNYAAIGFWGTNQVKIFYLGDETHRFEELKLAEPISPEDHLPVSTILTTFGTSNRPHLLVGLGNGTISSYALKTEIVLGEPSVRATDKKIFSLGTKPIMLNACTDLGRESNIFACGDRPALLFLKNDRLTASPIKLRDIHAGSVLHIPQFPSSFIFASASTLLIGQIRESQKIDVRTISLGLDTPIRLTYHRGLRAYGVVCQRKELNREDDREIYSSSFKLFDDITFEYLNNFTARPDEQMMCVTTIPDSTGEEDSDFLVVGTYEATGAEEDVSKGRILIFEEVPNRKLKLVVSHDVGGCVYAVTNVGANLAAAINGTLQVFSLHRSHDDIRIESVAKWSSAYVASSLICRGNTLLVGDAMRAVCILRWTGAKLETLYHDYASLWIQTLESIDEGGVIGAELNNNIVTWRKDGKLERDGMWYFGEGINRFRRASLNAAAPGAGGNNAGRGNLVFCTNTGRIGIVASLDEDLSMQLSNLQRNIGSVIQGPGKVEHSRRRAPQSTPGLPTILTQNTHAVGFIDGDFVEKFLYLDPSSDEVMRILEGKNKYEQLGNRYHDIVQMLEELQRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEH5</accession>
    <name>M5GEH5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactan 1-3-beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_50228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630152.1">
        <property type="nucleotide sequence ID" value="XM_040774980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEH5"/>
    <dbReference type="STRING" id="1858805.M5GEH5"/>
    <dbReference type="GeneID" id="63690042"/>
    <dbReference type="HOGENOM" id="CLU_016116_1_1_1"/>
    <dbReference type="OMA" id="TEITYEW"/>
    <dbReference type="OrthoDB" id="9970295at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04081">
        <property type="entry name" value="CBM35_galactosidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18821">
        <property type="entry name" value="GH43_Pc3Gal43A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU03258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="513" mass="56863" checksum="FA96CE9E8FACFFC2" modified="2013-05-29" version="1">MVDDKVLLPGPAQRSAPTVLFKATNLLLLCLLLCALPVLSNASFILDLLFRAISFFKHETVDPSFSLSEPSAAPRWIVPGARWLDTEGNSIQAHGGGMLKVDDVLYGYWFGEDKEHHASTFRAVSCYVSADLYTWTRLPDALVPLVGTSVSNESIVERPKVLHNSLNNDYVMWFHSDNLNYNAAEVGVAVSPTPEGPYTFLCSFKPFGADSRDIGLFVDDDENAYLLYASDWNNNFKIAQLTPDYRNVSNITHVFYGGGYEAPGIIKKNGTYHLFISGLTGWWPNANRHLSAPSLSGPWSEPEDIAPPLLRTYFSQNTYDLVIERGESEGRSMVSLFMGDRWKSNRLGRSSYVWLPMMWHENATVWLDWVDVFSMDLKTGAIVIPNGTTYHAAHGILSRNARVGKCASCTSKLAVYRLGAGGCVTIHGIQGNGAEHWVSLYYANPDRNWRETTVSVNGGPTQTVEQPDTQDSGAFLSVPVRLMLMKSSKNNITIGHNQTSYAGNLDKIIVYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5GEY2</accession>
    <name>M5GEY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630562.1">
        <property type="nucleotide sequence ID" value="XM_040772275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GEY2"/>
    <dbReference type="STRING" id="1858805.M5GEY2"/>
    <dbReference type="GeneID" id="63687337"/>
    <dbReference type="HOGENOM" id="CLU_399020_0_0_1"/>
    <dbReference type="OrthoDB" id="3269353at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="690" mass="77109" checksum="1D9E4C18B885A167" modified="2013-05-29" version="1">MSMRSSVIEDWTLEEEPAISSPSEVATTWGPPSPIDWPESPAVPMFHSPELALTVEHVPSKPTERLLSPPSSPMQSVQFLDGDEEAKTTSASDSLPEETRPVVWPFCDVPSFAAGSSRWANGGPHLYAEEQRPLAASQAYGFFDLYRAVYPHLRPYPPLACAGRDNPPPSHPLNKPDNSSFGWPYMKSTLHHEDWTPVGLATSLSLSMMPQSVTWPRAIDAFAQGWLFTQKSKSSSSATWSPSVDAFAQGWPYTQRPNKIPVLLDNHYPALTIYKPVYPHIEIYLSCIQSFSRPTSFSRVEYPHFDIYATVPSFQKVACRIPVALNLAIYPTIVVYPDVAQTSHAPTSIFPHSSSEYPWLVIYASVYPHIMPYPEAVPRMIPKPTFDMNVSLWNCYPYSAQRMYAPGYPDNLEIYPATSESWQLSHEEKAISIQTALQLRYPFMQIYAPQYPHFDIYPSVQHRVCNIADAPKLRILIGSKAPHPAVVAVQNHHHPTDTTHRHRHRSSSKDIPPVPPLPVDVLVKLKSTSSPNSPPQLISSTHVRINGTPQQALPSVASRSSSPLKTRKWKHSHQDLVRQVQEQQGLHLSSARQSSASSSPVNKKKWKHTHRDLVIQVFGSESQHHEVKTTTQILPPHEMSSEPVIRAGRPHSFYQAPRGCSGSVVGRPLSMAAHPTIPVGRLNLSKYPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF49</accession>
    <name>M5GF49_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_105995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630732.1">
        <property type="nucleotide sequence ID" value="XM_040768181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF49"/>
    <dbReference type="STRING" id="1858805.M5GF49"/>
    <dbReference type="GeneID" id="63683243"/>
    <dbReference type="HOGENOM" id="CLU_1758739_0_0_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF881">
        <property type="entry name" value="FI07970P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="148" mass="16994" checksum="0B99EFA28E1EB51B" modified="2013-05-29" version="1">MRDTVLCCLKVPKEQFDTRKWLSLPGACQQPLPPYLEENRDFLDEFKRECAALGCRVLGCLARAWGLEEEFFVGQHRYDEPSMDNFQLMHYVPYTPEYAEKDVFRLGAHTDWGSLTLLFQPSPGLQVRPPHYAHHLPPSAGEQGSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFD0</accession>
    <name>M5GFD0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_19446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633056.1">
        <property type="nucleotide sequence ID" value="XM_040771513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFD0"/>
    <dbReference type="GeneID" id="63686575"/>
    <dbReference type="HOGENOM" id="CLU_2739951_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU06162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="71" mass="8208" checksum="34E9994FE32B7764" modified="2013-05-29" version="1">MYDCSARRAVSAVLSVVHAVPLRPRQPKRADQIPFLSQSDMLVARPQSRYCRKLYASRWEGIYRGGRLLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGT0</accession>
    <name>M5GGT0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_19355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632917.1">
        <property type="nucleotide sequence ID" value="XM_040771466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGT0"/>
    <dbReference type="STRING" id="1858805.M5GGT0"/>
    <dbReference type="GeneID" id="63686528"/>
    <dbReference type="HOGENOM" id="CLU_140672_1_0_1"/>
    <dbReference type="OMA" id="NKGHKTE"/>
    <dbReference type="OrthoDB" id="9616667at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000001">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU06023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11778" checksum="07B63A64B30EA0E2" modified="2013-05-29" version="1">MAVTRTNLRFGANTGRTTTAIEKKPKPSHRKGVKNEKSKFVYSVVREVAGFAPYERRVMELLRNSKDKKARKLTKKRLGTLLRSKRKLEELLNVIAESRRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGT1</accession>
    <name>M5GGT1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_102981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632922.1">
        <property type="nucleotide sequence ID" value="XM_040767699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GGT1"/>
    <dbReference type="GeneID" id="63682761"/>
    <dbReference type="HOGENOM" id="CLU_1618957_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU06028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="164" mass="18130" checksum="570DFD5304D2D925" modified="2013-05-29" version="1">MQTYEADGREDYMADESIGDLETWGWQRRERASPPSRGKAGGGPVSVFRTSEAGVNRLGHDRLDDEVTPSLVQDRLSRIALIHATDSTPILPLFPTSAILRSDRIELPKLDNIRSIVYQDNMAVFTTQAAKMDVERCEKRTRRGSAFGEGDGEANTVVSAHALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN43</accession>
    <name>M5FN43_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Heavy metal translocatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_91987</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795880">
        <property type="protein sequence ID" value="EJT96795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623693.1">
        <property type="nucleotide sequence ID" value="XM_040777035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN43"/>
    <dbReference type="STRING" id="1858805.M5FN43"/>
    <dbReference type="GeneID" id="63692097"/>
    <dbReference type="HOGENOM" id="CLU_001771_0_2_1"/>
    <dbReference type="OMA" id="AMHRRHQ"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="857"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="885"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT96795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="910" mass="96362" checksum="7CE08BF4B9CD1C54" modified="2013-05-29" version="1">MFTQLSIGGMTCSSCTSAITFALTALPGVSGVDVSLISHSAGVTHDASVTSAAKLADEVEEIGFESQVVSSKPVKKAEEPKRIKSYFAVGGMTCSSPDLFTLSYLPSSALSIRTILSSLPPGLSGTLYRPPTLSELARVSQLKELNHRLLAFSLSFLFALPTFVIGIVGMLLLSSTNPLNKWCMSSAWGGATIGTLFLFALATPVYFVLAARTFHYHAYTALRTAVRRRPFRLSHLISFGNMDTLVSLSITVAYWSSLGMMARDTSLGKGNGTGATYFDSVVFLVFFILVGRCLEARARVMTGDAIALLGTLRPETATLLYSDAVASDMSEDQPAFRTRSIPVSHLEIGDRILLRPGSLPPADGILLSRSTTFDESSLTGESVPVPKLVGDEIWTGTTNLSSACVVEVTALGEETMLERIVRAVGDAQGRKAPVELLADRITAVFVPLIIWLSLAVLVIWLACALTNAVPGSYLSASDLGGSMGANVDTKANRVFFSFEFMIAVLVVACPCGIGLAAPTAQAVGAGLAAKMGVLAQGGGEAFQLATQVDTVVFDKTGTITVGETKVEDALFLDGEEKGWVRESVRVIEEGSSHPLGAALRTFCASGEAGVELLRSEEVAGRGAKGTVNVRGNQYEVIIGNEAFMLESGTNWPEGTDMRTEIQQWKAEGKSVVLVATRGIPNGDSTKAFTMAAVFSISDSPRPDSADAIATLRKLGKDVWMLSGDNEITAKAVADRVGIDEDHVIAGVLPQEKADHIRRFQAGGQRGRRAAGWTTAVLHRLGISSHQKRGDKAIVLFCGDGLNDSAAITAADVGVALGHGSQITVAAADFIILSSSLSTLPSLLHLATRVYRRQKQNFGWALIYNCAALPLAAGVFYPAGHTRLPPVWSALAMALSSVSVVLSSLALRWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FN62</accession>
    <name>M5FN62_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_112230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795879">
        <property type="protein sequence ID" value="EJT96890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040623788.1">
        <property type="nucleotide sequence ID" value="XM_040769377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FN62"/>
    <dbReference type="GeneID" id="63684439"/>
    <dbReference type="HOGENOM" id="CLU_1266859_0_0_1"/>
    <dbReference type="OrthoDB" id="5311491at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="23509" checksum="42321E5BB873B98D" modified="2013-05-29" version="1">MSFTWSTADLGVVVDGDDPITLRYGDTSPERSATPPYTTIIALHGSGFNATIRTHVASIILFEPPGLVYGIPLSEPLWEEDSRPAKVGRSFVDGLLRPLAAERVHLVYASVDKFELASQDLFTWDGVSTPDREAVSKLAFERIPPFLGLGVVYCSGTIIACIDGSKHVIDQCGNQVNVTTTVIPDGDHFLMATDPEAFNRAVISTIRELAAKVSDASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNI1</accession>
    <name>M5FNI1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_58833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624383.1">
        <property type="nucleotide sequence ID" value="XM_040775521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FNI1"/>
    <dbReference type="STRING" id="1858805.M5FNI1"/>
    <dbReference type="GeneID" id="63690583"/>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OMA" id="IKEHMAI"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF4">
        <property type="entry name" value="AMIDASE C550.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="85"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="235"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="545" mass="59647" checksum="21D2D0F84864F5AE" modified="2013-05-29" version="1">MSVNLVEATGSPVYMEQVHAIKQRRDSQIPASLRLPKEVIDSAPLDVTSIPASCGLLTDKELAITELDATSICQKIAAREITAVETVTAFGKRAIIAHQLVNCLTDIFLDEGISRAKELDEYYEREGKVVGPLHGLPISIKDHVPLKGRWASAGFLATVEVSQDDCLMTSTLRNLGAVFYVKTNQPQSIMHLETNSMYGRTLNPWNTSLTPGGSSGGEGALIAMKGSCIGVGTDIGGSIRGPAANSGIYGMRPSSKTLPMKGYLAFQFGADGVLPSTGPMCRSARDIDLFIRNVLASKPSLIDVSLVPVVWDVPTSFEKKLRVGIMEHDSVVLPHPPILRALAAAKAKLAASGLVEVVNYKPFRHDLGYDIIRELYFEDGGKIVRDLLSQTGERMLPLTEWVISPPYTKDHDATSLRALRTQRDEYRDAYSDYWNQTGCDVVLCPPFPGTANPHDTAKYWSYTAIWNILDYPGIVFPSGARLNPSVDVLESRTHFLSDADKLNEELYHATKMVGAPVSFQLVARRFNDCLLVAAQKVIEDILKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5FNY5</accession>
    <name>M5FNY5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_25579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
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            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EJT96643.1"/>
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        <location>
            <position position="95"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT96643.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="95" mass="10432" checksum="522866E6BED9E545" modified="2013-05-29" version="1" fragment="single">IVVLLGMHMNERPTPCRTRTNALFKTFSTQNSLLARSAENVLYFTIIITTSSPLARDLTATHATPSIGLELSGASLGEYADTPHIMVENWTILEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FP84</accession>
    <name>M5FP84_DACPD</name>
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        <recommendedName>
            <fullName evidence="9">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_25350</name>
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    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
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            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic initiation factor 4G family.</text>
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        <property type="nucleotide sequence ID" value="XM_040774127.1"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
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        <source>
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        <source>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="1692" mass="179482" checksum="942C8BE78B76DC7F" modified="2013-05-29" version="1">MSKASTASLPKTQPSTPASGSSTPATAASSTQATRPVSAWSRGPPLTARTAPTTAPLSAVPTSAPASAPAPAPAPVPSSAPAQKSAWNTPAQASQPPSGTVTPTGTGTGTHARKASSVVKDGIAAVAGNGASKPGSAMSFGSVGENARSTPTAAPASAPPTATVADAKTFGSLPATAKKDESASKKDAPAASASSEKPAEKPKDHKPKKKVDLNALFQVVPQPSSSAPSPSPSTTAGPSLPPTSPPPAGTPVTGRPPTGQGQSNIYNSIPMRPPPQNMPMMQNMPMMPGNMRPFVPSGPGRGGPPGQGPNGVPRPEPAGAGRGAGPGPGPGQGQQPGSPPPHGRGMMSPMMGMMSSGPGQQWAYYPGLPHPYYPEGQPMPNSPYTYWPQVQVPHPGMPMQGQQYPHPMQQQQGMVPVPVQMQFQGGPGPGQGPGQQLLVPQHTMSPGAHGRPLPGPGPGAQQQPLPGPGTPISISGLPSPLPSHVHPPGQPIPQGIQQLPPTPLPHPSTPSTLRSALPGPNPPNNPNFRYPAPTPTPGAPGPGSLTGPPTPGGASQLNSRATEFVPSSARKTIKITRDDGTPVSLSAFSTHSHGRSASVIGSGASARGSPAPGTLELKDTKEVKRVVVRLESEADKARREREAKEKEEKEAKEREAKEKEEREAREKEEREAKEKEEREAREKEELERKKREEEEREKERLLAEEKEKEKARLAAEAEAAAAAKAKAKAKAEAEEAEEKARKEEEARVKAEALAAAALVAAAAAKAEEQQKELERRQAQAEELAEKADTLSALPSAGASASQTPTSPSTPDLSAASISLKPLNGGFSDAKIRRPVPGALDLKSALNAAAKSAPPLSSAQASALLSARPIEDINAIQYPAGIRTPNPDLNAHGPPGKFRYDRDFLMQFMNVCKDRPETLPPLDAIGIENSDAMTQQYPQGGGRAPGGPQDRRNRASVSGKLGLGITGNPGAPFAGKGGFSMGNFQAPVRAGAEGDRYRSVSSFAGPAGVALVGRPVAMTRTASGSGLSGQVPGSPGGGNRNRSLRGRQRPESRQPSQMIPPPNTPGFEPIEPLQKSENRWKPQLAVPRSQRDREPADTPEMVERKVKALLNKLTLEKFDSISDQIVGFANRSEQETDGHTLIHVIKLVFEKATDEPAWSEMYARLCRKLMERISPKVFDVQVKNAEGTLIVGGQLFRKYLLNRCQEDFERGWAARRQLAEENAGGHGKEGEEAIFSDEYYAVQKAKRRSLGLVKLIGELFKLQMLTERIMHECIRKMLANVENPEEEEIESLCKLLTTVGQQLDTEKAKAHMTIYFQRMKEMVKILRERAERKEVSSRMMYMLQDIIDLRERYNWQPRQKGSAPGPMTIAEVHQAAEREQAQKEAEKVRQAMSRGGSRRGDPREYGPDGWQNVPSGPAARAPAPAKAGDLSKFGNISKQSGPIGGFGPSNVFKKADPKVARSEAAATPTRTNMFNILNAADGTAETEAMAHKAPSRKPSVDLSAGAAAQEAGGQRKRLKLLPRSIPLAKDEESAPPSAVESIDEVAGMSEQKAEALIKEDIQEFWQVGDLGEAANYFKDLPSNYHDKLIDKFVSDALNKKDADIVMVAGVFSRCAAAGTVSPESFKKGLLPTIEFLDDVAVDVPQAYPFMAKLLKGTQLSQADLEELASKISVEGSPLVAPKDKLLKEVAKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPS1</accession>
    <name>M5FPS1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_59118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624171.1">
        <property type="nucleotide sequence ID" value="XM_040775540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPS1"/>
    <dbReference type="GeneID" id="63690602"/>
    <dbReference type="HOGENOM" id="CLU_1481871_0_0_1"/>
    <dbReference type="OMA" id="QFPWMTR"/>
    <dbReference type="OrthoDB" id="4791183at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067122" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT97273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20092" checksum="F650BBA714D3CB4A" modified="2013-05-29" version="1">MLSSLLNALLLLVWANQASAAHANFHVQFPWMTRTQYPKTQPELQRFVPFCGDIIHNPQRYGRIYRNFLSFSGHPGDLVSARYTRTRVPRSAEDFPHAIFDDVPIAPSGQLCVNVTLPFDTQEGEYGVMYFQAVAPTGGVQYWCLDVRMSDIITLPEDHPAMCAAGNETLIPMPDEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FPY4</accession>
    <name>M5FPY4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_96207</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT98855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625753.1">
        <property type="nucleotide sequence ID" value="XM_040777353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FPY4"/>
    <dbReference type="STRING" id="1858805.M5FPY4"/>
    <dbReference type="GeneID" id="63692415"/>
    <dbReference type="HOGENOM" id="CLU_021483_0_0_1"/>
    <dbReference type="OMA" id="VWDKPDG"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000131">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000236">
        <property type="entry name" value="Vacuolar protein 8, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000128">
        <property type="entry name" value="Vacuolar protein-like protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="91"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="132"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="173"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="214"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="257"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="339"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="532"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJT98855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="593" mass="63393" checksum="6CCBDC47619A3184" modified="2013-05-29" version="1">MGNVASACKTCCGLRSPKAQGYEPLLLENEREAVADLLQYLENRTTTNFFTGSPLAALTILSFSDNVDLQRSAALAFAEITEKDVRPVGRDTLDPILFLLGSHDTEVQRAASAALGNLAVNVENKLLIVKLGGLEPLIRQMLSSNVEVQCNAVGCVTNLATHDENKTKIAKSGALVPLTRLARSKDMRVQRNATGALLNMTHSDENRQQLVNAGAIPVLVGLLSSPDTDVQYYCTTALSNIAVDANNRKKLAQTEPKLVQSLVALMDSPSLKVQCQAALALRNLASDEKYQLEIVKADGLPPLLRLLNSSFLPLILSAAACVRNVSIHPANESPIIEAGFLLPLIDLLSYEENEEVQCHAISTLRNLAASSENNKGKIVEAGAVDKIKKLVLDAPLLVQSEMTACIAVLALSDELKPQLLEMGICEVLIPLTNSSSVEVQGNSAAALGNLSSKPENGRSTADDYSAFNDVWDKPDGGLHAYLYRFLSSTDATFQHIAVWTIVQLLESGDETLLRNIKSSKLIMPHIQQLAVSQAPTPASGSPGSDAGGYSEEGEGEGTGEIATLSRRILELTDAADEDLRKSVHSALGAAKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQA0</accession>
    <name>M5FQA0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_24120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795871">
        <property type="protein sequence ID" value="EJT99040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625938.1">
        <property type="nucleotide sequence ID" value="XM_040773555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQA0"/>
    <dbReference type="STRING" id="1858805.M5FQA0"/>
    <dbReference type="GeneID" id="63688617"/>
    <dbReference type="HOGENOM" id="CLU_022828_0_0_1"/>
    <dbReference type="OMA" id="PMFMSFA"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="126"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT99040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="495" mass="54085" checksum="23BEC65D47CE9FF7" modified="2013-05-29" version="1">MSATLMHNNQTASNPWDLPASFAGLNDSDFLAMLEKQVNTDSLTQQSYTLTPPLSEEDSSPSPPHSELERTQTGTPEEMNHKRKLSPDDEDDLDDEAPAHKSHRDSMDGTENKKNRRKSTGGQKDETRVMKRKEQNRAAQRAFRERKEKHVRDLEDRVAVLEAEKAETANENENLKDLLNRLQTENQLLKQGQFTFSMPGSNKRSASDGSTDSSPDASSSTGQEPVFSQSSPPIDMSHNNPVFSTAGASEPSLTSASDSNLSMFGSFPVTPTWTTLATAPQYTSYRDPIYDRIFGGAGDISPYATRGDEEGEGGLVNLEELFGEDFGDLMPIVGDFSPAAEAVLAPIDTTMKDDHAAAASLPLVHDGHSAHDEHGDGCPRTRQDIINMMATSEPKTFGPPVAVPPAEPPKDQSPCTHAADLGLVEPLGKADPNLRNVPISEAWKQVRSNPHFEDCDIDELCLLLKEQARCGGGQPVIEEPNFNNILQHMGNQRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQS3</accession>
    <name>M5FQS3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_58247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624816.1">
        <property type="nucleotide sequence ID" value="XM_040775489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQS3"/>
    <dbReference type="GeneID" id="63690551"/>
    <dbReference type="HOGENOM" id="CLU_2413222_0_0_1"/>
    <dbReference type="OrthoDB" id="3364670at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="92" mass="10130" checksum="F574D457CA768CA3" modified="2013-05-29" version="1">MNSSQYCVHGIIAIVCCHNVLLHLTNLVDTGEKHFYTVALVQKVMDQLHTAATVGILYDIACQLHRSVRKVCTNSIPKNNTHSITAQADARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FQX7</accession>
    <name>M5FQX7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_118140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626313.1">
        <property type="nucleotide sequence ID" value="XM_040770530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FQX7"/>
    <dbReference type="GeneID" id="63685592"/>
    <dbReference type="HOGENOM" id="CLU_966506_0_0_1"/>
    <dbReference type="OMA" id="NGALHCA"/>
    <dbReference type="OrthoDB" id="5346979at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="288" mass="31027" checksum="40F7FF1A7AECA123" modified="2013-05-29" version="1">MTEHHDRSSTSYSSLTSGIIDTTKEHAASEERARKRSLAKVLFGASAVFFVTGIAGALVYARRAQVRMLEEDQRSKSETSTVEEPPSPTETRVLLQGTNATGPQPLVLPSRISTSSTGAPRLSLPRRPPKTAPANPLAISPIGALGAFGLATLTVVGVAGGVVWAVKKSIGVDDMEGFTGKTRLMLRSLFPGLSERIHRAITPRDNPSSVSSHSPSSTFASSSSHPLNVEEEAREWNVVDSQQRLTDAFAQGGIMRWAEQAGSELEAERVLEARKRAVRKEKRKDGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FR11</accession>
    <name>M5FR11_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PQ-loop-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_102407</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624167.1">
        <property type="nucleotide sequence ID" value="XM_040767633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FR11"/>
    <dbReference type="GeneID" id="63682695"/>
    <dbReference type="HOGENOM" id="CLU_019699_1_0_1"/>
    <dbReference type="OMA" id="DMCIFIQ"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJT97269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="278" mass="30431" checksum="9522F8980C4466AF" modified="2013-05-29" version="1">MALNDELSSVAGWMSIACWIIVYTPQIYENYTLKSGEGLSVLFVVIWLAGDLCNLGGALMAGLIPTVIILAVYYTLCDLTLLGQIYYYRHVHPTHIARVSPTPSETDPLLSPSSSELVATAKPTSSVWKKVLIYVLAVCFVLASGAIAWAVTRGKEVGTPGPGEGEGDVLEWKSQLIGWCSAVLYLGSRIPQILKNRETKCAGLSLALFIFAVAGNVTYVLSICIKSMQWRYLLANSSWLAGSGLTVFLDFIVLGQFFYYRKERLALVEDPVLESEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRG2</accession>
    <name>M5FRG2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_24717</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625156.1">
        <property type="nucleotide sequence ID" value="XM_040773811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRG2"/>
    <dbReference type="STRING" id="1858805.M5FRG2"/>
    <dbReference type="GeneID" id="63688873"/>
    <dbReference type="HOGENOM" id="CLU_071893_2_1_1"/>
    <dbReference type="OMA" id="ILETAWI"/>
    <dbReference type="OrthoDB" id="338231at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21692">
        <property type="entry name" value="GINS_B_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="8">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="9">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJT98258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="237" mass="26625" checksum="441613F24E7F5DF5" modified="2013-05-29" version="1">MSDWNTGTSWSNGQSHLPSPSPEPQEDTFPDDLDNDRTDPISLLVKAWMTERCSPDVMSFEGELVGKIMGYMDAQAKLIGVLKIDGASEEDHEKIGLVQMELDRVGWLLRSYIATRQEKIMRYASYINSTPAMQTRLSVAEQTLIESYQQIFEESLIRDVVGNLPAELQALDEILPDGRGMVSTPDLDKAVFIRTKQDCGPVLMPDGTPLEIKKRGIHLISYRLVEQLVLRGEVELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5FRQ3</accession>
    <name>M5FRQ3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="8">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 90 kDa subunit homolog</fullName>
            <shortName evidence="8">eIF3 p90</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF3, p90 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRT1</name>
        <name evidence="11" type="ORF">DACRYDRAFT_68793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJT99885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FRQ3"/>
    <dbReference type="STRING" id="1858805.M5FRQ3"/>
    <dbReference type="HOGENOM" id="CLU_011152_4_0_1"/>
    <dbReference type="OMA" id="LWGGPQF"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000419">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="39"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT99885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="729" mass="84596" checksum="611F411EA9B1845E" modified="2013-05-29" version="1">MPVPEPSVNGYHHDADEDIDYTDIDEKYAVHYDESFLDNIIVVDGIPIVKAERKERLVTKLGQDFNRLGASFKPGSLHMPWDDENGQNRGYVFIEYPTVDQANSAIAAIHGYRFDKNHAFAANRFADIEKFTNMEETYVEPGQEEFKAREHLRAWLGDPQGRDQYVILRGDDLQVFWNGRNGSSALVIGRPRWTESYVAWSPAGTFMATFHIQGVQFWGGPSWTRVRRLVHPHVKLLDFSPGENYVVTWSNEPIQIPENARTGPDIFSSDDEGNSVAVWDLKSGFVLRTFPSGQQGEDSATKKMVWPMLKWSGDDRYVARIQPGQQISVYELPGMHLVDKKSIKIEGMQDFEWCPWGDRDRDDQDGKTKGKRARENILAYWTPEVVNQPARVTLMSFPSRTQLRSKNLFNVSDCKLHWQNQGDFLCVKVDRHTRTKKSLYCNLEIFRMREKDFPVEVLEIKDAVISFTWEPRGERFCIITTNDPNFGNAAPGITIKTAIHFYQLERTKGDFRLLKTIENKTSNSVFWSPKGRHVVLATMGSQSKFDMEFWDLDFTGDDAPRSDKDPGANIQLLNTTEHYGVTDIEWDPSGRFVASSASAWRHTLENGYALWDFRGQELSKQVLDRFKQFLWRPRPRTLLSKDQQREIRKKLREYSKQFDEEDAAEESTVSAELIASRRRLIDEWNAWRIKVKRELKEEKGKRPQQRHLQEKVEEYVDEIIEETIEEVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FS33</accession>
    <name>M5FS33_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TauD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_111455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795875">
        <property type="protein sequence ID" value="EJT97934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624832.1">
        <property type="nucleotide sequence ID" value="XM_040769241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FS33"/>
    <dbReference type="STRING" id="1858805.M5FS33"/>
    <dbReference type="GeneID" id="63684303"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
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        <property type="entry name" value="AtsK-like"/>
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        <property type="entry name" value="TauD-like_sf"/>
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        <property type="entry name" value="TauD/TfdA-like"/>
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        <location>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT97934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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    </evidence>
    <sequence length="365" mass="41825" checksum="0394FB8DF26C2EE3" modified="2013-05-29" version="1">MSTETKLLPEHKMFDHESYQYKELLPTWPKYNYDPHVELDVKDKGLLADPEMKALLGAATHRDDLTPALGTVLDGIDIRQLSDDQKNELALLTAQRGVVVFHKQEATIHEMIKLAEYFGPLHVHSTTGIPEDPALKGAHVVWNDGTKPQDWINFNRDYFGWHSDQTYEINPPSLTSLKVVTAPKTGGDTLWASGYAVFSSFSPQFQRYLETLSALHSSDMQKQLAIQRGVHIRRPQTDCIHPVVRVHPVTGMKFLFINTAYTRQIVGVPKAESDAILAFLFSQVSACTEYQCRVRWGKDTICFWDNRCCWHTATFDFYPMKRHGLRVMPMGEKPMSVEQYEAKTGKKAKDWYKEKMRLLGEEMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT42</accession>
    <name>M5FT42_DACPD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_23085</name>
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    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="63688152"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="103" mass="11415" checksum="27BA48620C05DD07" modified="2013-05-29" version="1">MGSWILEIGGQEILKRNAEGRSLPRVDQCLMHVFGHDIMPYEFGYPAGLNVWVVARVGASDIPLRQLLWSRAFVAADSPGRDIASTLLQCISKRDSCKFVPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5FT68</accession>
    <name>M5FT68_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_109918</name>
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    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FT68"/>
    <dbReference type="GeneID" id="63684032"/>
    <dbReference type="HOGENOM" id="CLU_1704188_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT99193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="154" mass="16719" checksum="7E63F04514CEA446" modified="2013-05-29" version="1">MELGKKAPVSDDSPLEGPTWDLEETGSGQERESAGKNKDKSANESADVARPSHPQDDANAAEPRSRYSHYSMSAPSTAPHATQFLLPRTGERLAIVIIAAVILLRSWVLAALFKRRNHGHAEKGAQSANPPNLLLLRPPPPRPSSPPHRLRLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTP0</accession>
    <name>M5FTP0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_110678</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795872">
        <property type="protein sequence ID" value="EJT98784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625682.1">
        <property type="nucleotide sequence ID" value="XM_040769101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTP0"/>
    <dbReference type="STRING" id="1858805.M5FTP0"/>
    <dbReference type="GeneID" id="63684163"/>
    <dbReference type="HOGENOM" id="CLU_663965_0_0_1"/>
    <dbReference type="OrthoDB" id="10486808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067280" evidence="3">
        <location>
            <begin position="20"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJT98784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="414" mass="44397" checksum="1F8E0F6F80DB13C9" modified="2013-05-29" version="1">MECIPSLISVLLYLHTSFALPLQQADLLLDRRQVTAAFPDVFAGLPGSTSFRPAPTSPPSRVLPLTPGASAATPTSTSLAGVELPNQNTITNLFVPGTRFFPLGVVIICLIVITGLTVLMVIFVVWSRRRKRYIPPNVPISRPIPPKTPPAVKTPKTPPPAKTTETPLGLLEKSKRMTRMGRTSVILITSSFNYWANKRKSSALPALPYSAKALSFSSFGTTISSALPTPNVPIELQAEPMSAMQRQVSNASGLFSAGPLSVWDGRSLAYGPDSAVSRVPPTPLPMNFPAITPIEPKSSYIEQLETPVQGPGGVPRLPVIAISPVVSWPPPLPGTSIPPVPEIPPQFGRPQLSRLTIPNPIVISKRRTPVVAVAPHLDRLEEEEPEPAGRRPLPKVPPPPPPPHGPLPAPPDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FTS4</accession>
    <name>M5FTS4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytosine-purine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_22861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627953.1">
        <property type="nucleotide sequence ID" value="XM_040772986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FTS4"/>
    <dbReference type="STRING" id="1858805.M5FTS4"/>
    <dbReference type="GeneID" id="63688048"/>
    <dbReference type="HOGENOM" id="CLU_026016_2_0_1"/>
    <dbReference type="OMA" id="ARWGWET"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU01056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="489" mass="53651" checksum="B6FA36004AC8C8E2" modified="2013-05-29" version="1">MDNKALHSGWEEAQIEKVRHRSWVYRLLLSGIETRGTLPVALEDRTDPQFSKAFFIWLSANSNILSFSAGTLGPLFYGLGLRDSCLVILFFNLLCVSFPAYLATFGPKMGMRQMVHARYTYGYWPIAVPCILALASMMGFNILSAILGGQTLASVSDGSVSWTVGIVIVSVLTLALSFCGYKVLHFYERYAWMPVWIVYLVVIGIGAKSIAAPPPTEPATAGGVLTFGATIAGFVISFCGMMSDYTAYMKPEVPSWKVFTYTYIGLFLPIVIIQILGAAFAIGMGNVPEWQDAYNTNSVGGLLEAVLRPAGNFGKFLTVLLALSVTANTAPTIYSFCLIFQVFIPPARYVPRYVFSILGFAIMLALAIVGAHSFYETLSNFLGLIGYWSASFCSAIITEHLLFRHNDFANYDASVWDTPSRLPSGIPALAAGILSFALVIPSMNEVWFIGPIAQAIPGYGDIGFELALVVTMLLYIPFRWIEIRFRGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUB7</accession>
    <name>M5FUB7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_44073</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628208.1">
        <property type="nucleotide sequence ID" value="XM_040774554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUB7"/>
    <dbReference type="STRING" id="1858805.M5FUB7"/>
    <dbReference type="GeneID" id="63689616"/>
    <dbReference type="HOGENOM" id="CLU_078855_2_0_1"/>
    <dbReference type="OMA" id="WGRVNIY"/>
    <dbReference type="OrthoDB" id="2432613at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045328">
        <property type="entry name" value="Kre9/Knh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154:SF1">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067327" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="187" mass="18875" checksum="BA51BA18CFDB713D" modified="2013-05-29" version="1" fragment="single">LALLLAAQTALATIYATNPVASTTFTGGQTATISWEDDGTSPSLTQIGNASVGIYAGNSQQQTLLQMIIGSVNVATTASIQFTVDPTIGPNSNAYFIRFTALTVKDTTNPTYPYEQFSARFTMTGMTGTFNASVQAQINGATGAAAVPGASSIAPVSQTSTHPASNTPSPTASGAKTNATAAAKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>M5FUY4</accession>
    <name>M5FUY4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626252.1">
        <property type="nucleotide sequence ID" value="XM_040771290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FUY4"/>
    <dbReference type="STRING" id="1858805.M5FUY4"/>
    <dbReference type="GeneID" id="63686352"/>
    <dbReference type="HOGENOM" id="CLU_047855_0_0_1"/>
    <dbReference type="OMA" id="CAILLEH"/>
    <dbReference type="OrthoDB" id="2530165at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT99354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41793" checksum="0A6A86A998CEAD65" modified="2013-05-29" version="1">MNNNYDDPIEDDIDDMEEVQTDDLAALPQHLRDEIDHAFDRAARAVTGEEDDDSGRRRKRRKLNSGIPSPVEDMGGGFLVSEEPGGFLPSDEPTGSDPSKSHGSLLYRSPSFPSTSRQTHIPISLVSRALKLLRLPVDDDAVLATFREAATGWGERAGKAEEKGVSREDWRAVCAVLIGQREEGEMKRDDNDEEEDEEPEGEGGFMMDEEEESDLTDDEEDNYQPEDDEQGSSPSSDQGSEYEEAPASSSKPFKDKRKAKGKTRVRDQELELSELGYADLSVKKKQEVRDAFALFFEEEKGMKPKDLNGKGKQRETPPLITRRIGAADLAKVAKLLNEKLSAEEIEEMLEMFTSAADKTVGIQDFSKIMIRGNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5FV54</accession>
    <name>M5FV54_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_27013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795868">
        <property type="protein sequence ID" value="EJU00139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627036.1">
        <property type="nucleotide sequence ID" value="XM_040774291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FV54"/>
    <dbReference type="STRING" id="1858805.M5FV54"/>
    <dbReference type="GeneID" id="63689353"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_1"/>
    <dbReference type="OMA" id="GFNVFLH"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="237" mass="26349" checksum="B15166C680C4E5A9" modified="2013-05-29" version="1" fragment="single">SYALITGASDGIGRALALEFAKWGFNIILHGRNPPKLAKVREEILALQKEKEKKKGKGKDVLLWVQDAAEDVDWPAVRKRFEQLEITVLVNNVGGSKLQTLSFDQQPLADVTRTVHINALFPFWLTHTLLPLLRQPYPTLLLNVGSMAGVIPPPHFAAYAGSKAFLDRFTHALDLDERISGSQVKVHYLQTATVLNSSGVMRRSLTVPSAEEYARGAVRVVGGTRRVVFPYWMHGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVB5</accession>
    <name>M5FVB5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_117272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795867">
        <property type="protein sequence ID" value="EJU00209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627106.1">
        <property type="nucleotide sequence ID" value="XM_040770350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVB5"/>
    <dbReference type="GeneID" id="63685412"/>
    <dbReference type="HOGENOM" id="CLU_1555207_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="172" mass="18858" checksum="B137E01FD7DF0EE2" modified="2013-05-29" version="1">MASPSTITTGSRASATSSRSVFAETRLSAVTKSTVSSAQISSTPMRSSTSGITTTKHTHMTLDGVVRDELGHALYHNCSVEDILQSIFDLDDAQLLERQGLARDLAQTFSEDEELKRLEENYLRQSLEPQAYVLFCELVNAIIDRLGIEGDNNRFLAIGQKNTRSWDGGSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVB6</accession>
    <name>M5FVB6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_84823</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624159.1">
        <property type="nucleotide sequence ID" value="XM_040776703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVB6"/>
    <dbReference type="STRING" id="1858805.M5FVB6"/>
    <dbReference type="GeneID" id="63691765"/>
    <dbReference type="HOGENOM" id="CLU_063928_0_0_1"/>
    <dbReference type="OMA" id="HWMERIP"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJT97261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="312" mass="34523" checksum="4061ECC049109B27" modified="2013-05-29" version="1">MFLSPSVFSYVADGIHVEKLLNWVKASILILYLFTKADYHTLFFPIAMFALVAGPIQQPIHILTTAVWIWIHQLQCNINNQLVSISEDKDNKPWRPLPAGRITSPQAQQLHGVVTILCLLLSTIGGYKMVVASAALMFTCLLYDQGRGSAHWMERIPLVVLMYGIFEYGSTRVISKPLYPSLDETARTAIISSLAVIATTAHIGDFPDVEGDAADGRSTIPIAFPRSSRIFTPLLFLGWSVYMVNMWDLGKISASLCVGLGSLVAGRNWFYCDKVNDKMTYKLHSVSGLLHSSFGHVLINYSYGSLLSTSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVI6</accession>
    <name>M5FVI6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Lysophospholipase</fullName>
            <ecNumber evidence="2 9">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_91648</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the lysophospholipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="2 9"/>
    <dbReference type="EMBL" id="JH795877">
        <property type="protein sequence ID" value="EJT97346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624244.1">
        <property type="nucleotide sequence ID" value="XM_040777013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVI6"/>
    <dbReference type="STRING" id="1858805.M5FVI6"/>
    <dbReference type="GeneID" id="63692075"/>
    <dbReference type="HOGENOM" id="CLU_014602_0_0_1"/>
    <dbReference type="OMA" id="PQNRSEC"/>
    <dbReference type="OrthoDB" id="4084751at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF33">
        <property type="entry name" value="LYSOPHOSPHOLIPASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8 9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005140972" description="Lysophospholipase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="PLA2c" evidence="10">
        <location>
            <begin position="21"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJT97346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="626" mass="68205" checksum="65144F007BF474D7" modified="2013-05-29" version="1">MFISMLFIALFLGSYGPTYHTCPSNVSFLRPATNLNPAESAWVSERKSVVLSSLSSYLSRLDLHDFPLERYLSSLSHNSAYIPTLSLAISGGAAPATWTGMGVMQALDDRFPPSVAQKTGGLLQSLTYIAGLSGGSFPVISYAVSDFPTTADIVIQYDPMVNPLSPTGASGEALYDEEVFLEIGEKLQAGFPVSLADFLARVYSYEFIPGPGAGINTTWSGVTQLPRFENHTMPLPILEFVIVSSDAPAFYVGDVPILIPQANSTLVEVSPFEWGSWQGPRTGFTPTKYLGTVLLNGQPVNTSRCVNGFDNAGFMLATASCAWNLWYVIDATNGTGPNFAKRGLVLSSRDAYVPPVGKRSLLSAAPEAHALSKRKTIFFPEAEFDLLLSAYNTSFNATIPSILTAPYPNPFFGINNDSEPYLSVVDGSESGQTIPLAGVMQPVRKPDFIIAYDVSQETTYGWQNGTNLIDSALWAKGFDIPFPKIASATTMLNRGYTLRPTLFGCKNASVPLLLYLNNAPYSAYTNFSIIDNQLDPPQVTDILTNSFNIVTQGNGTLGKDWAECLGCAAIQRSVERLGWKTTPQCEQCFAEYCWNEVFNPSLLLEPRLSFAAWNQTHQYFYTNGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>M5FVY2</accession>
    <name>M5FVY2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoglucanase V-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_42981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628908.1">
        <property type="nucleotide sequence ID" value="XM_040774528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FVY2"/>
    <dbReference type="STRING" id="1858805.M5FVY2"/>
    <dbReference type="GeneID" id="63689590"/>
    <dbReference type="HOGENOM" id="CLU_064531_1_0_1"/>
    <dbReference type="OMA" id="SLWNGAC"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22278">
        <property type="entry name" value="DPBB_GH45_endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22514">
        <property type="entry name" value="EXPB1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Expansin-like EG45" evidence="1">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="177" mass="17968" checksum="F5B345214AAA15AE" modified="2013-05-29" version="1" fragment="single">ERATGGYLQNPSGSASFTYYSGCSSPACGVTASGYTAAMSQLSFGAASGAGAGDACGRCFSLTGTADPYSPSYTGPFKTVVVKLTDLCPAPENQVWCGQTQANPENQYGAPVHFDLCQDTGASMAFFPSGHGALTGTYTEVSCSQWSGTDGNPLWTGACISGQTTGNWPSTACGNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW20</accession>
    <name>M5FW20_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pectinesterase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_127574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628958.1">
        <property type="nucleotide sequence ID" value="XM_040770940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW20"/>
    <dbReference type="STRING" id="1858805.M5FW20"/>
    <dbReference type="GeneID" id="63686002"/>
    <dbReference type="HOGENOM" id="CLU_012243_2_0_1"/>
    <dbReference type="OMA" id="EWIDHEY"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31707">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pectinesterase catalytic" evidence="4">
        <location>
            <begin position="30"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="237" mass="25727" checksum="3764FA3FB27BDD95" modified="2013-05-29" version="1" fragment="single">LIVAPTFNASLIGMGTVGLPLQPKFGNVDFKAYHIDFRNLAANYAISQALVTDISYAKASFYGCNFASYQDAWYTGRNTSTYVKGGTIYGETNYVFGFGTVCFEQVTFANRGCGGALVAWKGTNKSDRTGTTPITPGNHYDAYISNSQIIRSPDANTTLDLTSKCYLGRPWNDDATTVIIRTYMDDTINATGFIPLSGRPQVILNPTYYAEHGSYGRCPGGNISQHASADHVLDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5FW46</accession>
    <name>M5FW46_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DACRYDRAFT_54006</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627486.1">
        <property type="nucleotide sequence ID" value="XM_040775220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FW46"/>
    <dbReference type="GeneID" id="63690282"/>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OMA" id="WTTYGCS"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EJU00589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="513" mass="56007" checksum="8CF5E77F35AF6A19" modified="2013-05-29" version="1">MSTFSYGYDTGIAGGVVSNPYFQQVFGLDAGNANDLSSNIVSVLQAGAFFGALGSAPLSGWIGRRWTLIICSLVFILGAILTTVAESQNVRGLSYIYSGRVISGLGIGAISSVGPTYATEIAPKNIRGKITGLFQVWVAAGVLLSYWVNYGVSIHSPPNSPQVWRIPFGVQILPAGLMALFLLFCRDTPRFLALKGRRQEALDTLCWYRRASPLDDEVKEEFAETEATVLEEKGVRAGLTFREAVFGKGNWPRYIIAFVFMLLQQFSGQNIVGYYGPQLFKSIGYVGQTPALLASGVYGIVKLVATALFIAFGVDRFGRRWALFGSAWGMGITFMIVGAIYLTHPPNPNSPNPSGYSQAMAAMIYLFCVAYSWGIGPLPFLYCSEIFSNRTRHIGMAWSGMSQWLFNFTISRIALDMETALGGKVFITFGAINIGGMATFAYFIPETKGKSLEEMDIIFGSVKAEDRNKEIERAGLEYAADMKRTDPEKGAVVRQPEMTEAPKPETAHIDNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWD5</accession>
    <name>M5FWD5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_97095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795876">
        <property type="protein sequence ID" value="EJT97696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040624594.1">
        <property type="nucleotide sequence ID" value="XM_040777423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWD5"/>
    <dbReference type="GeneID" id="63692485"/>
    <dbReference type="HOGENOM" id="CLU_1390185_0_0_1"/>
    <dbReference type="OrthoDB" id="3356964at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT97696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="196" mass="22741" checksum="8697E3C2158901B9" modified="2013-05-29" version="1">MTMVPLSPHGSHIFVRVDHDPDMQRFHDAIRNRRLPENNFQILLDQTAFLVKEQSWFDQQSGRWYNVCKRCGASCGHNMSPTWQMHPCGSLKITLLCEIRGGQRRVADGETALLHLKQRALRLQTYAAWLLWDLVSEHLIELFLQHDTHAMVDIGMLLDDRLISPRVLNAAPNREAVLRQVAKDVQEYEDSEWSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FWQ6</accession>
    <name>M5FWQ6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Homing endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_51366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial DNA endonuclease involved in intron homing.</text>
    </comment>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629280.1">
        <property type="nucleotide sequence ID" value="XM_040775036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FWQ6"/>
    <dbReference type="STRING" id="1858805.M5FWQ6"/>
    <dbReference type="GeneID" id="63690098"/>
    <dbReference type="HOGENOM" id="CLU_126084_0_0_1"/>
    <dbReference type="OMA" id="FRRIILM"/>
    <dbReference type="OrthoDB" id="5381460at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF4">
        <property type="entry name" value="LAGLIDADG ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00961">
        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="2">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU02386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="17053" checksum="087E92A90F274E68" modified="2013-05-29" version="1" fragment="single">VTGFTDAEGHFFVSLKNKNTKLLPNITLGYKVSQKEDSGGVLYDLQRFFKCGRVVKEREGYLKYEVTKFDDIICKIIPHFKLFPLVTSKFLNFVDLEKVAEILVNNKKITLKESDYIFNIISNMNKGRTFEDKFHFTNSLNISLKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5FX04</accession>
    <name>M5FX04_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_29169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU00954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627851.1">
        <property type="nucleotide sequence ID" value="XM_040774310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FX04"/>
    <dbReference type="STRING" id="1858805.M5FX04"/>
    <dbReference type="GeneID" id="63689372"/>
    <dbReference type="HOGENOM" id="CLU_003921_8_2_1"/>
    <dbReference type="OrthoDB" id="5596707at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU00954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="102" mass="11148" checksum="8D527631C1AEB636" modified="2013-05-29" version="1" fragment="single">ILNGSSGIVGISEQCCEQIGLTYTLIKGWQMESVNGLVDQLLGHIPNLCIGVSGLNFHVQAFVLPNLPFHLLLGRPFHVHASCVMQDYMDGKQKIQITCPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXN5</accession>
    <name>M5FXN5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_89593</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627447.1">
        <property type="nucleotide sequence ID" value="XM_040776921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXN5"/>
    <dbReference type="GeneID" id="63691983"/>
    <dbReference type="HOGENOM" id="CLU_001265_54_6_1"/>
    <dbReference type="OMA" id="IWQMILF"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="27"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU00550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="467" mass="50407" checksum="1808977408703252" modified="2013-05-29" version="1">MAIDDQVASDERTPLLLDGDHPLPKLQIFLLCWGAIVEPIAFFSIFPFINQMIFETGGVDEASVGFLSGVIESIFSLTQTVFMLLWGRAADRYGRKPVLVISLAGVTVASTFFGFSQTVWQMIVLRSVAGVFAGITVTVRTMISENSTPKNQARAFSFFAFATNLGIFVGPLIGGALSKPCTQYPTVFGNFALFEQYPYLLPCIAAGAMSGVGALLSVLFLKETRPIRDGKTHDHATIIQPPRIKEILAAPGVIPVIIIYQYALLLGIAFTAVAPIFFYTPIPLGGFGYSPPQISLFLAGCGISQAVWLLVAFPIFQRKWGTGNLLRACAWAWPISFSLFPLLSALIRNGQETLYWTLVPVAVVGPSGVSMAFTAVQLALNDIAPSHLALGTLNGLALSLMSAVRAVTPATFASIFAFGIKHQILAGYLAWAVMIVTAVGFIVVLRWLPEKAEGRPILKKPLDEQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXP6</accession>
    <name>M5FXP6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_52970</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628161.1">
        <property type="nucleotide sequence ID" value="XM_040775141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXP6"/>
    <dbReference type="STRING" id="1858805.M5FXP6"/>
    <dbReference type="GeneID" id="63690203"/>
    <dbReference type="HOGENOM" id="CLU_000995_3_2_1"/>
    <dbReference type="OMA" id="RHQQTDK"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.870:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="438"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="757"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU01264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="929" mass="103554" checksum="317EF348FACEAAE0" modified="2013-05-29" version="1">MPAPSSLPASSAPDRSSPRRNAQNGTAGRRQAADPLALNGNADDQPRPPQEEDPDTRQRRRARRQFEEDVPQVKDQTGEKVRESFEVFLKDYTEDVLLPVTPASDAFPPDVEGEKYYITQIHNMKQNETSTLYVDFSHLLERDEVLARAISDQYYRFLPYLRRALQSLVREFEPDYIYLNPTSTSAQGGMTRDFSIAFYNLPLVSGIRDLRTERIGTLLSISGTVTRTSEVRPELLFGTFTCGNPICKASVRDVEQQFKYTEPAQCQNLQCSNRTGWDLNIEQSRFSDWQKVRIQENANEIPTGSMPRSLDVILRGELVERAKAGDKCVFTGTFIVVPDVSQLGLPGVNAEMQREARGGRAGADGVASQGVTGLKSLGVRDLQYKTAFLACMVRDSDMRASAADVRGEDNETDREAYLESLTKEEYEELMAMVNQDYLYSSLVSSIAPTVYGHEIVKKGILLQLMGGVHKQTPEGINLRGDINICIVGDPSTSKSQFLKYVCGFLPRSVYTSGKASSAAGLTAAVVKDEETGEFTIEAGALMLADNGICAIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPIGGRYNRKISLRANVAMSAPIMSRFDLFFVVLDQCNEDIDLKIASHIVNVHRFQSEAINPEFSTETLQRYIRYARTFNPKMTPEAADVLVEKYRLLRQDDASGVSRNSYRITVRQLESMIRLSEAIARANCRDEITPAFVREAYHLLRQSIIHVEQDDIDFDDDEPAPAHADGDVDMDGTDAPGPSASIGADLYSSPVRPTAPPTQAPEQPTVPTKLRITHDKYVNMMNMIVIHLSEVERSTGTGLELEELETWYLEQMEEELTGPQELMLEQAIFHKVLKKLVKDNYVMELRGDNQESLMSEESQEVPEGKIIYIVHPSVDTDFTSSSLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5FXQ8</accession>
    <name>M5FXQ8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_17987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625199.1">
        <property type="nucleotide sequence ID" value="XM_040771322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FXQ8"/>
    <dbReference type="GeneID" id="63686384"/>
    <dbReference type="HOGENOM" id="CLU_416787_0_0_1"/>
    <dbReference type="OrthoDB" id="10579860at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJT98301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="71651" checksum="24F0260BCA891C1E" modified="2013-05-29" version="1">MSGKAFFNLRIGSKDPKYSFLESKKHRLSVNALLTTGLVLATPAPSATDDPAMASNAIVRIKESVTHKPLNTSMCSGDYTVPLVVPATTSYTLSAASCISTTVILPAPKPKSVENASLRAITSTPLKRVSSSAVGVHLPLLVNAWHPSCLDASAAVPEVTIVPADDLHPRHAMPDSSIVSATPVAMAYELLDQATLQIVFCGLEGKERPEAFRHLQSLGNMLIQLVVLMELPSLFPGATADVYKVSFSHLIENQVLIQWQAKTAQILSGLGLLADAAIECDFPQRIAAVANHASIVTTPILADTFQAFVGAIVVHNNHDMTVSYKYCREALVAHLERSALLRSITTHEEKKAAVPSRRSKKGRLTESAPRAVHRRGRVSINEIDSAAQMKVEETVAGSNSCSVPQSAQNSCGGKASHPNLPERPTLYPRPDFTGNEENGRDRANGPRRGHGGQRKFKPRPEPLRRVFENDGLSPDELRIRDGLPPLALKEDSPGNKAQKPAVRIPVDLHPPKRQLAAVIDEHEDSPAVQIEDTWRPPKRKEKELCEGHGEDTVKKAHSPQRPQRPVKRIKRTFEGLSGCKLQLDEYMRKHYPTVDMNYKPWGIFQLGVCRDGDRNIEIPLVIGAPLNIKVTGAGLTAADAEEDAASQVLKQLPAIESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5FY24</accession>
    <name>M5FY24_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_110903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795873">
        <property type="protein sequence ID" value="EJT98461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625359.1">
        <property type="nucleotide sequence ID" value="XM_040769143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FY24"/>
    <dbReference type="GeneID" id="63684205"/>
    <dbReference type="HOGENOM" id="CLU_692666_0_0_1"/>
    <dbReference type="OrthoDB" id="5596707at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJT98461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="398" mass="44260" checksum="83E197F4E8BD07B6" modified="2013-05-29" version="1">MANLEGMVSQIYMLMNRQPAMQNQLAAQQNSYGQPSQNTYSNNTSATGANWVPVPAENYPKQNGYSPWNTESVLCHFNGVSTGCTDKIATCPGAQKYVDKGLLEKDSTYHVLAGSQFIPHHWPGWDLKEKVNNYYKDHPEHRPKLQATPLIAFHNMIIEDIGLDSKFEVTVDHLVLHILTEKHDNTVEWNDEEIKVLMAKADQLRKRHVASTGKFVKVSKVYTPAARKEKSEAHVHHSTTHVASIGVDELEKLDAIPDPPKPHAKWPKNAEDETVLQALVVTLPETWVQVSSKVLASACPLFNKVLKEAYGKKPIIPDVIQVTKIQDGKAPIYQIKGILEDMDRLLVGKDMVPLRQIDCLIGNYDTPIPCILDGSSGIVGISKKCCEQIGLAYTPVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYQ7</accession>
    <name>M5FYQ7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_108367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627932.1">
        <property type="nucleotide sequence ID" value="XM_040768639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYQ7"/>
    <dbReference type="GeneID" id="63683701"/>
    <dbReference type="HOGENOM" id="CLU_3014106_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="56" mass="6018" checksum="6FEE49E77B45AB62" modified="2013-05-29" version="1">MDFLVLVPISKPSPEPRVCKLPHARPRLGWAGSSVDRYVAAAASALANNEALTPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYU2</accession>
    <name>M5FYU2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DACRYDRAFT_78082</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>itraconazole(in) + ATP + H2O = itraconazole(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33503"/>
            <dbReference type="ChEBI" id="CHEBI:6076"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33504"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630090.1">
        <property type="nucleotide sequence ID" value="XM_040776311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYU2"/>
    <dbReference type="STRING" id="1858805.M5FYU2"/>
    <dbReference type="GeneID" id="63691373"/>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OMA" id="GYFRLAM"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000066">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001370">
        <property type="entry name" value="p-GlycoProtein related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="699"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="744"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="823"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="925"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="962"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="30"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="364"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="705"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1025"/>
            <end position="1264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU03196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1272" mass="139038" checksum="9B3D50C4213EF936" modified="2013-05-29" version="1">MAADVERDPKPVSFFTLFRYHSWLDIFLNLLGCVCGAAAGSAQPLMTILMGRLVTQFVNFTVALASGESSQIAEASAEFKDAAAKNALYLVILGIGAYVVVHTYMFIWIYTGEKATKRIREEYLKALLRQNIAFFDTLGAGEIVTRIQSDTHIIQIGISEKVPLIASALSGFLTGYIVAYVRSWRLALALSSILPCVLLIFAAFFSFHSKYEEISLKAISQGATIAEQVISTIRTTKALGAEKKLFAVYQEFVNTAAKAMLTTTFIDGALFGIFFFIQYGAYALAFYYGTTLILYGIGNAGTVVNVFLSLVTGSLSLILLMPFLENISNARVAAAKLFATIDRVPTIDSASEEGLRPEVVHGHITFENVLFEYPSRPNVKVLKSVNMTFEAGKSTALVGPSGCGKSTTVALVERFYDPLNGSIKLDGHDLRSLNVRWLRSQIGLVGQEPVLFATTVKQNIAYGLTGTPWENTSVEEQFRLVREACIKANADGFISKLPEGYDTNVGQAGLLLSGGQKQRIAIARAIVSNPKILLLDEATSALDTMSERVVQNALEKVSQGRTIITIAHRLSTIKNADKIYVLNEGSLEEEGTHNELLRNPDGPYSVLVHAQQLRELAERAGDPEKVPLPPHVDQVVVADEEGQEERSTDIPLRRIATGPSVVSEAFIKRSPMEDDEEGKRRYPFTVIVKRLARLNRRALPYYISGALFATANGMIYPLFGIVFANAINGWSSTDPTEIRHAGNHYALLLFIIAICSGILFAGQNSMTEAASVVLTQRIRALSFETIMRQDVGWFDDERHSVGALTAGLSENARKVGDVAGDTLGTLFQAGITVIGGGIVGLCYGWKLSLVGLACVPFLLSAGYLFLRVVMLKDERDKLAHEDSAQFACEVASAVRTIVSLTREEASYLQYRHFLDQPFRNAKKTALVSGGFFGLSQGCPYFVIALMFWYGSRLVASQEYTTVQFFVCLMSGTFGVMQVATSLSFMPDVSSGAMGSRKLFELLDSTPEIDTDSPDGKHIQQLKGQVAFRNVHFRYPTRLEVRVLRGLNLDVQPGQTVAVCGPSGCGKSTTVQLIERFYEVLYGVIYVDGIPLPELNVANYRKNVGIVSQEPNLYAGSLKFNLLLGATNPDEVTQADLDEACREANILEFIKGLPEGLDTDVGNKGTALSGGQKQRVAIARALIRKPKILLLDEATSALDSTSEHVVQLALDNAARGRTTVTVAHRLSTIQNADRIYFMQDGRVAEAGTHDELVKLRGGYYELVRLQALTRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FYZ3</accession>
    <name>M5FYZ3_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_107461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628616.1">
        <property type="nucleotide sequence ID" value="XM_040768475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FYZ3"/>
    <dbReference type="GeneID" id="63683537"/>
    <dbReference type="HOGENOM" id="CLU_1525101_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="176" mass="19370" checksum="5566C4A61C3C9E20" modified="2013-05-29" version="1">MNVSARSNVLTLARDLTTVKSLAQTQQVSQNAASLRPHSPFIQPHNRKLRSSQTRFLYLLTMDNVSISATYSSSTSDLGGGTDAVNKYEDVAYDAYMQGRQAYIDHFFPPSYASHSSSNALSAAIPFSTMAPTTAIPNVEFQPSPIVINNNCTTNIIHSNNTTYRNNNNSHHNNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ19</accession>
    <name>M5FZ19_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_15148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630185.1">
        <property type="nucleotide sequence ID" value="XM_040771077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ19"/>
    <dbReference type="GeneID" id="63686139"/>
    <dbReference type="HOGENOM" id="CLU_1626984_0_0_1"/>
    <dbReference type="OrthoDB" id="3227715at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="163" mass="18081" checksum="DB6A213494909DB7" modified="2013-05-29" version="1">MSDVATRPSRRRRHASSSHAPTSPETSRNPASPDKRRPSIATDDRTELELLVLSTEEFEKEVERRLGLGRPGAVEEATLSEPVLLPRPKTKEEEEALHAKVMDLLRARVTALEKEEDPEFDPLCPLPQDLAGIQDDPLFGKLETLATQIVSTQPCATGIPERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZ81</accession>
    <name>M5FZ81_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carboxypeptidase C</fullName>
            <ecNumber evidence="2">3.4.16.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_79454</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.5" evidence="2"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628716.1">
        <property type="nucleotide sequence ID" value="XM_040776397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZ81"/>
    <dbReference type="STRING" id="1858805.M5FZ81"/>
    <dbReference type="MEROPS" id="S10.001"/>
    <dbReference type="GeneID" id="63691459"/>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OMA" id="IHGPHAN"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067389" description="carboxypeptidase C" evidence="7">
        <location>
            <begin position="20"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="488" mass="53819" checksum="DF20A6855F21C272" modified="2013-05-29" version="1">MNFLSKLVLSLLAFKATQAIQTSFQPIDFPAPERELAHILPGEYTQLSHAAFPGYGVRVKRTEGWCDTGVKVYTGYLDVAQGAKHMWFYFFESRRSPATDDLVMWVTGGPGCSSSMDMLMQIGPCTVDPSGNGTLYNPHGWNAEVNIFYLDSPVNVGFSYSEFGEEVYTTEDAAKDAAAFAFIFTEAFAEFKGRPFHLAGSSYGGRYVPVFASEIWDMNRSAEKRGFTPINLKSIVIGDGITDAKETILAYYDMACTSASVPPVLDISTCVRMRRALPRCRELLTASCELEQSDLACTAATLFCENELSAPYRVTERNPYDLSDNECKGGIHALCYPIFNSISKYLNTPSTRAQLGVDPAVGVFVGCNNTINAGFRERFDSYRPTSFYVSSLLERGVDALIYVGTYDWICNWVGNIRWLEALEWHGQAAFNAEALSTWAGGEWKAAQVEGKTGKLLYATVQGAGHMVAYNKPSAAVAMVNKWIGAREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>M5FZH7</accession>
    <name>M5FZH7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628816.1">
        <property type="nucleotide sequence ID" value="XM_040772757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5FZH7"/>
    <dbReference type="GeneID" id="63687819"/>
    <dbReference type="HOGENOM" id="CLU_1594482_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU01919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="167" mass="18470" checksum="4C9566FEEBE820AD" modified="2013-05-29" version="1">MGAWIYVGIPCRAFGVGLVRQLSEWAPSRPVIWNSVAPLMLMRKAFVKTCLLSGPLLCEVCITYWWTGGSSCAHDRMTTRPKLSMILTYGPALPRLSDIRHPMTTAFRAGDCILPRSLKSVSFFSAVLRGPAFLSTLPGFCAHVGPQGRIPHQGFPFSLQYLNMIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G088</accession>
    <name>M5G088_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_23848</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795870">
        <property type="protein sequence ID" value="EJT99231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040626129.1">
        <property type="nucleotide sequence ID" value="XM_040773417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G088"/>
    <dbReference type="STRING" id="1858805.M5G088"/>
    <dbReference type="GeneID" id="63688479"/>
    <dbReference type="HOGENOM" id="CLU_053034_0_2_1"/>
    <dbReference type="OMA" id="VKMKLFQ"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000003">
        <property type="entry name" value="COP9 signalosome complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="12">
        <location>
            <begin position="55"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJT99231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="401" mass="43705" checksum="B54A30249E8EF856" modified="2013-05-29" version="1">MANAHAHAALQTFSIENDILNVPAQHELYKFDTAADKKVQQAAPWSKDPHHFKSVKISAIALIKMVIHARSGVPWEIMGMMQGKVTGDLIVILDAFALPVQGTETRVNAAAEANEYMVLYQEGSKQAGRMENTIGWYHSHPGYGCWLSGIDVDTQNQNQKYQDPFVAVVVDPNRTISAGKVDIGAFRTYPEDYKPPLSSSSQQYQSIPLNKIEDFGVHSERYYQLPISIFKSPLDDKLLNLLWNKYWVGTLSQSPLISNRSYAISQTLDLAEKLQRISGSLSSRQPPAIALPPRSSATSTSALMANLATSDITATPGKGKEKETEKPKVEKERKVEETQLGKAVRDSTKIASEAQHGLIAQVLKDVLFSARPGEGIESSTAGLGGGVTGVEQQIAVVSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0C9</accession>
    <name>M5G0C9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_14739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630590.1">
        <property type="nucleotide sequence ID" value="XM_040771052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0C9"/>
    <dbReference type="GeneID" id="63686114"/>
    <dbReference type="HOGENOM" id="CLU_801730_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="346" mass="38561" checksum="A80529A874F450B4" modified="2013-05-29" version="1">MTKPLELVKRIIPSVEVQSRQHTKIGSPALCAGPVLQTGSVVSPKAEAVIMAGGKDMDSKANLWIHCYEPHTWKNKKMGKTTREMIAMFDKLMKKELQAREAALEVIKAQINNEKNHCTPKGKIGTIKSRSKSAGSILIMLGQIKCESPVKSGKKEPTADIDSNKLNTTKNIKVQIERGNKTNAANNTQTSKRIIRTRSSNIRDYLTKTEEDKKPALTHSRLSSAGTNRSTKRMHSNTNKSGMENKNEESKDNFIWMTTKSPEETKICYSAPHTRSQTSKEGKMGSSSTGIRTGYNKNDPLSIIWKMEDGMILLKGKHPEIKFGTLFDNLEDLAVIHGRKLQDKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0X9</accession>
    <name>M5G0X9_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF1212-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_52290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628697.1">
        <property type="nucleotide sequence ID" value="XM_040775096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0X9"/>
    <dbReference type="GeneID" id="63690158"/>
    <dbReference type="HOGENOM" id="CLU_007078_4_1_1"/>
    <dbReference type="OMA" id="TIFMGVC"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="79"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="508" mass="56317" checksum="9496ED5AB9C45174" modified="2013-05-29" version="1">MSRISSRESSPEGELKHKRSQNYFSFKHREPTPEEEEKQEEERQKEAERRRRKRQRKRRLEKEIFITMHVAAILQRPEFLLKLARALMMFGAPTHRLEALIQATGRVLDMNVSCVHLPGVMLLSFNDDTTRTSETKFLKQPQALDLERLQDVHAVYNAVIHDKTGVKDASDRLDEIMRGRSRYRALIAIIIGGLCSAFITPISFSGSFLDAMLAFPLGCLLVLIQQLASRNELFTHVFEIVVALLLSFISAALAATNRVCYAAVASGSILLILPGFIVLTGALELASRNIISGSVRLMYAVIYSLFLGFGLAIGGEFYTAITGQKVIGIGLTNGLTCPVHDDNGPWWQQQASPWWAFLCVPGFSFALSLRNQAPWNRKEFVVMILISCAGWATNHFSSLKFVNRTDIIAMLGALVVGVCGNLYGRFIGQGMSFVVMVTGILFQVPSSINGLLSFASLANTGQDSYSAGFNIAEQLIEVSIGLTVGLFIAAVITNPFESRRRGYGLFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G0Y6</accession>
    <name>M5G0Y6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_25181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
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    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
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        <property type="protein sequence ID" value="EJT97447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_040774048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G0Y6"/>
    <dbReference type="STRING" id="1858805.M5G0Y6"/>
    <dbReference type="GeneID" id="63689110"/>
    <dbReference type="HOGENOM" id="CLU_060600_0_0_1"/>
    <dbReference type="OrthoDB" id="3357826at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="5">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EJT97447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37856" checksum="C9E7EF34DFE775F6" modified="2013-05-29" version="1">MSKRNLAISETRLVRTPTTNSKSKRDGEDITCVISWNVETPVPFLDLHHTVSSAGMSSYLEWDWPEFICLQEVRARPSDKDWMMAMCTAANGVSPLDRDGEMERREDGGLTYTAYWVLNVSRCRQRRYGVCTLVAHLWVKWFDGWELVNVYALNGSDFPWVDPRMEGDLLAKLLPQKTRNERKREFNMLLLEEIKKMRALGLRLVLIGDFNISLAKVDCYPCLRMQYPHALARKQFNEVFIPQAKVVDVYRAFYGSQKAYSWFAKGKPVGSDAARVDYALVDCQLIGEKGEGRVMGTGYGRKNVRTSDHGIVWLDMCGMNNLGLSEARAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="3">AhpC-TSA-domain-containing protein</fullName>
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        <name evidence="1" type="ORF">DACRYDRAFT_106600</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dacrymycetales</taxon>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040768303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G1C3"/>
    <dbReference type="STRING" id="1858805.M5G1C3"/>
    <dbReference type="GeneID" id="63683365"/>
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    </dbReference>
    <dbReference type="CDD" id="cd02970">
        <property type="entry name" value="PRX_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="EJU02529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22874" checksum="E2CC3C512760CCB7" modified="2013-05-29" version="1">MFEDTFSPDAPPTADELVKASAIDLDVEDGSTVPFGSLISDSGKTVVVFVRHFHCSMCQDYVTQLGSIREEALDAANVSLIVIGCGDRSVIPEYRERTEYRYPIYANPRKELYVALGMTRRTFHAAPPGEAPKSYIRAGKWAYAIRGIMKGPLSHPVSYIKAGDNQQLGGEIIFEPGPQCTFVARMKHTADHTEVKDLMEKAGVEYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G2Z5</accession>
    <name>M5G2Z5_DACPD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_20293</name>
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    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
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            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631495.1">
        <property type="nucleotide sequence ID" value="XM_040771874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G2Z5"/>
    <dbReference type="GeneID" id="63686936"/>
    <dbReference type="HOGENOM" id="CLU_739724_0_0_1"/>
    <dbReference type="OrthoDB" id="10474512at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="374" mass="40758" checksum="8D19566B4679ACEF" modified="2013-05-29" version="1">MTTDIDMNGSGPTRPDLSSPPSAGEDAGDKSLSSGDPKWRIQSVRWDDALVNRLLSSIRANPDWASSIARGALTSIDPSGTARGKAPLSKTDAIREVTRALFEGDPEYDMDDVAVQKSLLVSVRNKLYKLQPLDEYLAAPDGKYSSVAGAARKEHVESVDQDTGPVGAVRRSLRVPLSKKYAEEVPESDASSSRASPRPARTGRGQALAAKGGVPRHAPAEATVRRPWRPPLPLRPQFVASYQPLAPVRTVADIRRTYFINEKAYLSASLDRLTREAEERSRLDDEHLRLLRLEIEAREREKDENSKRYESKAARLREKISNAEEEIKSNTTEASTASASTAQTTSSTPLISTSPSVLAPPTQNGIPRPLSTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5G306</accession>
    <name>M5G306_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_21409</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629978.1">
        <property type="nucleotide sequence ID" value="XM_040772383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G306"/>
    <dbReference type="STRING" id="1858805.M5G306"/>
    <dbReference type="GeneID" id="63687445"/>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_1"/>
    <dbReference type="OMA" id="IRIRRHN"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11610:FF:000009">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="596"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU03084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="967" mass="108918" checksum="94C85F17F316EDEF" modified="2013-05-29" version="1">MYTRWKEDPKSVHPSWDVYFSGHKEPKPARTRPSASGSDLVREEGEGETEPQVMPLAGGVPSLHFSGGTEVSDHLKVQLLVRAYQVRGHHIANLDPLGINDADLDDAIPVELTIEHYGWSERDLDKVIHLGPSLLPRFATGGRSTMTIREIIDNLKSIYCGPIGFQYVHIPSKEECDWIRERVELPVIWDYTTDEKRMILDRLIWSESFEQFMASKYPNEKRFGLEGCESLIPGMKTLVDRSVEHGVKDVVIGMPHRGRLNVLANVIRKPLEAILHEFSGDVSPDDDAGGDVKYHLGANYVRPTPSGKKVSLSLVANPSHLESENPVVLGKTRALQHIANDENEHETALGVLMHGDAAFAGQGVVYETIGFHDLPNFSTGGTIHLIVNNQIGFTTDPRFSRSTPYPSDIAKTIDAPIFHVNADNVEAVNFVAQLAADWRAKWKKDVVIDLVCYRRYGHNETDQPSFTQPRMYKAIEKQPTVLTQYTKQLIANKSFAEKDIEEHKKWVWGMLEKGAAASEQYKPSSREWLSSPWQGFPSPKELAEKVLPQSETGVEIDILKHIGKVISSWPEGFNPHRNLARILQTRGKAIEAGEGIDWPTAEALAFGTLALEKIHVRLTGQDVERGTFSQRHAVIHDQQTEQQYVPLNNLGGDQAAFVVANSSLSEYGALGFELGYSLVSPDALSIWEAQFGDFANGAQVIIDQYIAAGERKWAQRTGLVMSLPHGFDGQGPEHSSGRMERFLQLCDDQPNIYPSEEKLSRQHQDCNIQIVYPTTPANLFHVLRRQIYRDFRKPFILFFSKSLLRHPMARSKLEEMTGNTQFQRYIPDPHPDSLVPPEEIRKHILCTGQIYYQLLKEREDRGIKDIAISRVEQLSPFPYDLLTPHLDKYPNAELQWLQEEPFNNGAFTYVAPRLRTAGKATEHHKGKVIQYGGRTPYSSVATGSKGVHKKETESYLNQAFGPRENTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5G310</accession>
    <name>M5G310_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MAGE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_102028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625040.1">
        <property type="nucleotide sequence ID" value="XM_040767606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G310"/>
    <dbReference type="STRING" id="1858805.M5G310"/>
    <dbReference type="GeneID" id="63682668"/>
    <dbReference type="HOGENOM" id="CLU_027982_0_1_1"/>
    <dbReference type="OMA" id="DANDAWI"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJT98142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="37298" checksum="315172135157FD15" modified="2013-05-29" version="1">MAADLVRLALFTEYKHGPLRRDEINKKVLGKYTRAFKTVFAAAQETLKDTFGMELVALKTAGHRERLVLEEADEAPDANGVTRKKIVPAGPRAWILRSCLSESIISAAAERDQSTAEAEEDEWLHLPDDPLRPERAPGTLIAWQSADDVGLQGLMFVILSLMLVNGRSMPDRIYASVPLTTASGKNVSLDTYLGTLTRLGYLDRTRTHLAALGTQAPPTQAPGRGRRGRGSDDVEEGDVSYEWRWGPRAEAEIGEKRAAEFIADVYLNRREEVQGIEDSDEEEEPQPTRRGKGRGKQDAASEKRRLKQARKEKDRREVQRILKEVERAAGGDLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3E3</accession>
    <name>M5G3E3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_31804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795874">
        <property type="protein sequence ID" value="EJT98282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040625180.1">
        <property type="nucleotide sequence ID" value="XM_040774354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3E3"/>
    <dbReference type="STRING" id="1858805.M5G3E3"/>
    <dbReference type="GeneID" id="63689416"/>
    <dbReference type="HOGENOM" id="CLU_082854_6_3_1"/>
    <dbReference type="OMA" id="FRISHDW"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJT98282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="83" mass="10135" checksum="E6EF0519DF6CA1B7" modified="2013-05-29" version="1" fragment="single">PDYVPRPPNPFICFRQDWLRRLERGEIAYSGPRDQRTMSFRISHDWREMPEQEKGKFRREALQRKKAHAAKYPGYKFAPRQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3I4</accession>
    <name>M5G3I4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_62982</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631680.1">
        <property type="nucleotide sequence ID" value="XM_040775720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3I4"/>
    <dbReference type="STRING" id="1858805.M5G3I4"/>
    <dbReference type="GeneID" id="63690782"/>
    <dbReference type="HOGENOM" id="CLU_010247_0_0_1"/>
    <dbReference type="OMA" id="IKYAWYE"/>
    <dbReference type="OrthoDB" id="1368803at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Protein arginine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="11">
        <location>
            <begin position="31"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="10">
        <location>
            <begin position="305"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="12">
        <location>
            <begin position="470"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="660"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="660"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="340"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="421"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for specifying symmetric addition of methyl groups" evidence="7">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU04786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="727" mass="80373" checksum="9AFA5D173788C7A4" modified="2013-05-29" version="1">MCLQQPVGVGANHASTSTSREGEVSRGEDLEKEAEEWRLHPKFEREEVTVTRLEETFSLIGMVSAWLELDSPESGIRYDSELALRQELAYATYLDVRTVVLPPPRNRAHAADYARSINAILNDTFGSYMQIAIRIPVSEVERGTGSPSGLLAGRECGGLKSPQIVLSPGSIGGEEEEGGLDSAWEMWDVIRTVCGYNARLSIVLDLSPPFPLRPGAMDRWSAEPIRHLFLPATSFIPNAKGYPVLAKATQVFLKEVMQFLPIVILSKTQANLHGAGGSKGYAEYIRFLEKTSRPLQAMRTEGTLESFASTYMDRVQAPLQPLMDNLQSSTYAIFERDPVKYERYEEAVFQALQARGQKPTVLCVAGAGRGPLIARTYKAIQRCSLGRTTLYAIEKNPNALVTLQERNTLEWNGAVTLFFGDMRSVELPEKIDILISELLGSFGDNELSPECLDGAQRFLKEDGISIPSFYTAHVAPLSSSKLYNEVLHQTVGDETKNAETPYVVMFQATNVLSGEGGGVRGICGTKVQECWSFEHPRRDLFVDARGLPFSNTHNTRSAHLTFHIPHSGVLHGLAGYFEAHLYGDVSLSIHPETKAQKSNNMLSWFPFYFPLKDPLYLPANAELDVHLWRMTSRQKVWYEWYAESFLPAPTPTTSVMGYITPQTPNTPRQGSITPVRPPRPSPMLDASPSVEGPASFMDLGGGGELSRVKIGQTSLHNPGGRSSWIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3K8</accession>
    <name>M5G3K8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_65474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630153.1">
        <property type="nucleotide sequence ID" value="XM_040775786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3K8"/>
    <dbReference type="STRING" id="1858805.M5G3K8"/>
    <dbReference type="GeneID" id="63690848"/>
    <dbReference type="HOGENOM" id="CLU_787598_0_0_1"/>
    <dbReference type="OMA" id="TEHCKIC"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="130"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="134"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39636" checksum="118AB53E3BE99BAC" modified="2013-05-29" version="1">MLSHLYSDNGTANDGSSRAMMISHGDCYVAVFLLTSNTPNSTKIWIAFDAQAGSLPDLTLYGLSIPLMLFPSDGEAIDYLWQLLRGMSTNDVSIRGHIFAPSGEETPLELDYPEFFQIEEPVEPEVPDPTTFRCGICMEDEQVTDRIRLNCAHEFCTSSLQGVVSSRVEEGLLPIPCPTCLAEDTDTSNYMTRDFCQRLDLPDRVADPWERLEVEEFGVMISCRRCGESGMIDREEFLAVDYVSCPFGGCIYRWCRHCDQPAGLFIRIKRADAADRYSRISQAMEEFGWEICPGGCGTRIEKTVGCYHMTCPAPGCHRHFCYRDGALIVRSEDRNAALEAVRAHYRNCQQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5G3Z3</accession>
    <name>M5G3Z3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_21852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629824.1">
        <property type="nucleotide sequence ID" value="XM_040772573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G3Z3"/>
    <dbReference type="GeneID" id="63687635"/>
    <dbReference type="HOGENOM" id="CLU_829051_0_0_1"/>
    <dbReference type="OrthoDB" id="8300194at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="85"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="335" mass="37096" checksum="847A998B64C7E338" modified="2013-05-29" version="1">MMVMFAPPALRSQANFGEVYRKLRDSNSARVDPPITDPIMFPDWVRAYLDHTVPPTPSQSIPPHDAVDACVGPRLVSVGSPYGGHRVVRVAENVLVKANMPYASSEASTMRYVAARTSIRIPRFFGGDQTRIMMEEVGGCNLDTYIARMTPTQLHELSHLLKRYLDDLHGLKFHNAQLGQVDGQPFRNQTFGVGVLPSDAFQSLQAFNEWLDPLLVEALGSQGAADVIARLPKMDGRFLIHGDLQPKNIMVHFSNPDSSRSSMEIAIIDWGSAAIFPSRSWEWAGMVWGIGEMDYGGKWHVVLRTICPDLGEAKSPLRHEVDAVLKVRGALSSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G406</accession>
    <name>M5G406_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_50554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630303.1">
        <property type="nucleotide sequence ID" value="XM_040774992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G406"/>
    <dbReference type="GeneID" id="63690054"/>
    <dbReference type="HOGENOM" id="CLU_095758_0_0_1"/>
    <dbReference type="OMA" id="RFTEMEC"/>
    <dbReference type="OrthoDB" id="2505969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU03409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="26322" checksum="A0A8220292C566E5" modified="2013-05-29" version="1" fragment="single">KYLLACLSKLLEVYRPGMAISYDIGCKHSKTVAHSSLGTHAKALGLHFFVGAFHGYAHNQKCQLMYHPCFLCLAGLEDFETNKHIFSKQNLMAHLFCHGSCYHCHMILLLFWSWWDEDCQVALADFIYDNYRQALHILAMVQPSVINFQHLHQLSDEDFARFLQEEQDYFNGLIAEPEEDVVAFRYLETLQSLASARYVPHLPCLLLFLTSKQAEAVRIRLRWLCPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4J0</accession>
    <name>M5G4J0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_117167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627644.1">
        <property type="nucleotide sequence ID" value="XM_040770333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4J0"/>
    <dbReference type="GeneID" id="63685395"/>
    <dbReference type="HOGENOM" id="CLU_1042144_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067462" evidence="2">
        <location>
            <begin position="21"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU00747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="267" mass="28589" checksum="F4988157004CEE41" modified="2013-05-29" version="1">MIPIKPVLLTFIFATILSLAAPIPSLNTRGYQLDAGESAALQSRTPDPNPPQDDQYPASDGGQYPSTPDLSAGDSSAPPSSPLQPIKQFKDKAKRFVLNLVGKKPEATPAPTAAQAHMQVQPQPAAPAPAHVTIGGGVSHESVHNELKTVAEAHMKEGNDGLAADTYHLQAQHLSSTPNTSPGGKQKQAGNPAKAGGFNDPNHLLKLQLEAESKSKTSYQAWEAGGYQSPPVSEHTQQLQQHVYEKYKQVTRQDAYHAGCIKFHNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4N3</accession>
    <name>M5G4N3_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycopeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632100.1">
        <property type="nucleotide sequence ID" value="XM_040771656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4N3"/>
    <dbReference type="STRING" id="1858805.M5G4N3"/>
    <dbReference type="GeneID" id="63686718"/>
    <dbReference type="HOGENOM" id="CLU_118873_0_0_1"/>
    <dbReference type="OMA" id="ETHTISF"/>
    <dbReference type="OrthoDB" id="3342934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004067510" description="Glycopeptide" evidence="1">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="16138" checksum="CAF9887A115ACF54" modified="2013-05-29" version="1">MKGFFASLATVAAAALTVAAETHTISFNNKCGHGTPTLVQGGNILSKGGDYTANCPFASAIAYLQTGSCGLNGEGCSMVELSLINSQTSTADVTLIPPHTFSVTTGFQFYGVCPGVGADCTSANCCPDNAFCTPTDYTAQRYCNEDNVNLSITFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Q6</accession>
    <name>M5G4Q6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DDE-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_74397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632130.1">
        <property type="nucleotide sequence ID" value="XM_040776064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Q6"/>
    <dbReference type="STRING" id="1858805.M5G4Q6"/>
    <dbReference type="GeneID" id="63691126"/>
    <dbReference type="HOGENOM" id="CLU_018294_5_2_1"/>
    <dbReference type="OMA" id="MATFCAN"/>
    <dbReference type="OrthoDB" id="162969at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="69"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="138" mass="15815" checksum="DD522FFCF80E16ED" modified="2013-05-29" version="1">MGLREFHWHGEAGSVPQASVEAARTRIRKITDQYELQNIFNMDEAGLFGKMPPDRGLANSPMSGLKAEKTRLTYPFTTNANGTERMPPYILGHAQMPRCLQNCSGTQLGFDYHWNQKAWMTSELFNEYLKDINDWAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5G4Y7</accession>
    <name>M5G4Y7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol polyphosphate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_46803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632225.1">
        <property type="nucleotide sequence ID" value="XM_040774725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G4Y7"/>
    <dbReference type="STRING" id="1858805.M5G4Y7"/>
    <dbReference type="GeneID" id="63689787"/>
    <dbReference type="HOGENOM" id="CLU_025224_0_0_1"/>
    <dbReference type="OMA" id="HRYPGWT"/>
    <dbReference type="OrthoDB" id="62798at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF286">
        <property type="entry name" value="5-PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU05331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="406" mass="45356" checksum="7B8EE63E3AE8E5B9" modified="2013-05-29" version="1">MEQKRLRVLIASYNTALQGNKGLPQDLVEWVTPALSPTHDLPAEDQVPPDFVAVGFQELLPLQLGCEFSNMTCSVLSTRDALIRQQLEKNLSIDSTEPQKYSLIAQHARVGIALLIYAREETVAGRVRDVQIRGVGCGQLGMGNKGAIGVRFRLSAEDGIGEGEIFTFLTCHLAAHTYNLPQRIRDYQTIVSSLLFSPSAHSTGPSQIYATTHLFVFGDLNYRLSQAPDPVQLLTAGGREQLREVDQLWMSREAGRTLHGLQEGEFWRFRPTYKYIMGSLEQYHGKRTPSWTDRILFATHDTIPIKPLLYTSIQSYTTSDHKPIMALLLLPPETHDARPPLIDDRVPYPVNKNAWLRIALGTTLDRTVGYAWCVLWLTGGGRTSVGLLAVLAILGVTLWWFGAFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5B2</accession>
    <name>M5G5B2_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_116855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795865">
        <property type="protein sequence ID" value="EJU01017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627914.1">
        <property type="nucleotide sequence ID" value="XM_040770273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5B2"/>
    <dbReference type="GeneID" id="63685335"/>
    <dbReference type="HOGENOM" id="CLU_042067_0_0_1"/>
    <dbReference type="OrthoDB" id="2576334at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="369" mass="38917" checksum="F7EABDB3EC3CBE12" modified="2013-05-29" version="1">MFHFWGSEVLLIADGLSYGSHTATFSVAITGSGQSLDFYGGVVTLSAGPAGTTIQPEQFIDNTSNRWEYQPFVWLEASALGDYGGTHSYACNYLEQVTAAIQFSGSSIIEIIGSPASNSFGYTVQFNNAETVYNATNFWWAQRQVMFFAGGLDPTQTYNLTLLDFDVNQPTGPPGLNTSGFWCVNLDAAVIVPVLLPANATSTSTSNGAGLGTTGPSGSNGLSSGAIAGIAIGIIFSTENTGHAVYSSSIDGSVNGPNMVQPPDPIPFVSPPSDPLTSAFASDAPISVVIGATSSSSFKAEMSTRSPYEKAGHTQIRQRRGGETSGGNDTRHAQEVLQNAPTDDLIAILNQRLRVDQADNLEEPPQYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5C6</accession>
    <name>M5G5C6_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630773.1">
        <property type="nucleotide sequence ID" value="XM_040768187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5C6"/>
    <dbReference type="GeneID" id="63683249"/>
    <dbReference type="HOGENOM" id="CLU_1713182_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012994596" evidence="1">
        <location>
            <begin position="16"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="153" mass="16826" checksum="513D33757FD0854F" modified="2013-05-29" version="1">MPHWSMSACFQCALCIVNDQCTWDIIAIVHEFTASGLQGGKLATWVGYFGHSARKTQHVGGSFHKHILDKDAVKALLDFDSQNNLLWMQVYQSATVPPPQVDLPPLGLKPHGFLWSNECTPAIAGPLHVDVPSEKDISLDYSSDDCDGYDKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J5</accession>
    <name>M5G5J5_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_19978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632425.1">
        <property type="nucleotide sequence ID" value="XM_040771747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5J5"/>
    <dbReference type="STRING" id="1858805.M5G5J5"/>
    <dbReference type="GeneID" id="63686809"/>
    <dbReference type="HOGENOM" id="CLU_054590_0_1_1"/>
    <dbReference type="OMA" id="PTEWYPP"/>
    <dbReference type="OrthoDB" id="2147163at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU05531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="249" mass="26879" checksum="30103734AD943177" modified="2013-05-29" version="1">MTTIVNDNKACCSLPPAEAEYTPKGEYVDVAGFKSYTIGDKNSKTVIISVMDVFGFSAQTVQAADILSTSGAYVILPDVFEGKPAASDLFSPPQSPEKQQTIQTFFSTVGSPPTALEKISKIVAELKSKGIEKIFEIGYCWGAKVTILSAAKDRINGIIMCHPSMLAAEDADNCLVPVANFPSGDENVQLMATINEKLKAKPFGNNCIEKTYADQIHGFAATRADLKAEGPLAAYKDVYQRSVDWVKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>M5G5J8</accession>
    <name>M5G5J8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DACRYDRAFT_20684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU03974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630868.1">
        <property type="nucleotide sequence ID" value="XM_040772034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G5J8"/>
    <dbReference type="STRING" id="1858805.M5G5J8"/>
    <dbReference type="GeneID" id="63687096"/>
    <dbReference type="HOGENOM" id="CLU_001724_12_1_1"/>
    <dbReference type="OMA" id="NPMISAT"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EJU03974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="568" mass="62285" checksum="34094A2B1DA21328" modified="2013-05-29" version="1">MARHSIIVPFSLAWGHLRPECGLAVNLVRRYTDLFISFLCEVDFVNRAKDEMSRQCLSEDERNSLLSRIRVIACGYPQPPMTPELFQMMMSMDPRDVHSPSRETCADANEMIDKVIDEQTFVDELGQEWGPVGAVPKVLICDVIMGGVAVPAKEKHNLSVFIWYIGSIASFTRSFAPPKHGGRGEGFADECEAIFADEERRNGRSFGDVVLDMWIRDHRVPGDIVRLAGMPPYFQWEDYPQQVWYSTMFNVLVGGSKLVDTADGFLLPTLEELENEGHKDLIQWARPRRVLCLGPQLPPALLSDAARASAEALAKLDVNFHASPAVDVSDPHGKHTSTVDTNGHGAVDPAIAFLDKTLTEYGPHSAIYISFGTLFFPGEEHMKILIETLLALEKPMPFVLAISSGRLSEDMKVAVEKSKRGLAVAWAPQQPMLSHPGLGWMITHCGGGGTFESLSSGVPVIAWPFIGDQPQHALLVSQVLDTGFDLLQVRNGAPGMPALRGDIAAGGVPILGTEEAIKTELRETLERAQGKDGARKRENAQKVKEVILNAVKQGGSAHKALGELDLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>M5G699</accession>
    <name>M5G699_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_107910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628254.1">
        <property type="nucleotide sequence ID" value="XM_040768557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G699"/>
    <dbReference type="GeneID" id="63683619"/>
    <dbReference type="HOGENOM" id="CLU_844742_0_0_1"/>
    <dbReference type="OrthoDB" id="3143319at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU01357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="329" mass="36989" checksum="3E98C08704818CDC" modified="2013-05-29" version="1">MLIREMTLSQSLIEEREKYCVKQDGAVHVLYLAPSGQTPPAVETLKQQTTALLSEDGWHTPALPKPPKLRQVGRSYVYALPPPLLSSLERSRRSIPAWDDLIELPSLTLSHFATSDYLSTLLPTPNLWTLIPQPHLLPSPHRIPQLPPPCPKEFHPKEKVSPYARSTLYIPISRRPPYDGVSQAMLSPTWPLPRRVDPSPSGEKWEYGLVIWTPLSIHRLWAFLIKIQEKGNCGPLGICYVPSHLASVAQRKSSLAVPTTDRPKKRPKSVQDTRKDDCAYVKVYCPTVTREWLVHALRNFPASREEGSRKPLGHAKFASVQDDGSVFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5G6D8</accession>
    <name>M5G6D8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_16107</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795864">
        <property type="protein sequence ID" value="EJU01392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628289.1">
        <property type="nucleotide sequence ID" value="XM_040771165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G6D8"/>
    <dbReference type="STRING" id="1858805.M5G6D8"/>
    <dbReference type="GeneID" id="63686227"/>
    <dbReference type="HOGENOM" id="CLU_007383_8_2_1"/>
    <dbReference type="OMA" id="RWNLAYP"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="107"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="263" mass="28470" checksum="3AF4041D49187A20" modified="2013-05-29" version="1">MSAKLVAVIGATGTQGGSVVGALLAHGGYSVRAITRDTNSAKAQALKSKGVQVVFGSLTDEASVVKAFEGVYAVFGITVPFTNDSEELQGRNIVDAAKEAKVPLLVCLFDQKSEVDKYARSSGQPTVIIHTGVFMENLIKGHLQRDASDPNRWNLAYPVLRPDVPLPLLCVGGDLGRIVVSIIDHWEDDTWKAKLTKDVLVAAPHLASVNDMISTLKKPVYGLVNDGYLQYPQQTILEELGIKTTSFETYAQEKVLPYLQSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>M5G795</accession>
    <name>M5G795_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DACRYDRAFT_113990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631498.1">
        <property type="nucleotide sequence ID" value="XM_040769736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G795"/>
    <dbReference type="STRING" id="1858805.M5G795"/>
    <dbReference type="GeneID" id="63684798"/>
    <dbReference type="HOGENOM" id="CLU_106918_1_0_1"/>
    <dbReference type="OMA" id="CIPCGAR"/>
    <dbReference type="OrthoDB" id="74807at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EJU04604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="17460" checksum="F402BDE683CD2F49" modified="2013-05-29" version="1">MPPKRSNDRKQSSRSSAQYTIDQVLRRHRRYLDELERANYHRLASDGAAEDKERLAVTEAKRGERKKSTQAVRGLLLYRKNLQTLIDESGIKDLPQGTPSYLTVATPAPVEPAKRFCISCGYWGAYRCQKCGEDYCSKKCGEWHDEFRCGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7J6</accession>
    <name>M5G7J6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_75569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase subunit 6B family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631588.1">
        <property type="nucleotide sequence ID" value="XM_040776142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7J6"/>
    <dbReference type="STRING" id="1858805.M5G7J6"/>
    <dbReference type="GeneID" id="63691204"/>
    <dbReference type="HOGENOM" id="CLU_133964_2_0_1"/>
    <dbReference type="OMA" id="NEWIAKW"/>
    <dbReference type="OrthoDB" id="1107506at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00926">
        <property type="entry name" value="Cyt_c_Oxidase_VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.140:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 6B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003213">
        <property type="entry name" value="Cyt_c_oxidase_su6B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281:SF8">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 12, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000278">
        <property type="entry name" value="Cyt_c_oxidase_6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU04694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="85" mass="9790" checksum="D4D13D6509728417" modified="2013-05-29" version="1">MSDTDQSASFVLQTAGFDARFPNQNQTKHCYQNYIDYYKCIAAKGEDFPPCKQFFRAFNSLCPNSWIGQFDEQRENGTFPSSLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G7X8</accession>
    <name>M5G7X8_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DACRYDRAFT_15938</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628879.1">
        <property type="nucleotide sequence ID" value="XM_040771153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G7X8"/>
    <dbReference type="STRING" id="1858805.M5G7X8"/>
    <dbReference type="GeneID" id="63686215"/>
    <dbReference type="HOGENOM" id="CLU_017779_4_1_1"/>
    <dbReference type="OMA" id="YNEDWMR"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="66"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EJU01982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="508" mass="54259" checksum="0701C7DCB353F952" modified="2013-05-29" version="1">MFALTLRRQLHRSLPPLTRGLAQLTQTDIDHFLTLLPPSSVRASLAPGTSTPADLEGYNTDWMGKYIGGSRCVLTPKTTEEVSKAMGYCFERGLGVVPQGGNTGLVGGGTPTGEDQVVISLSQMNRIRSFNPSSGVLTADAGCVLQSLATFLASEGYTMPLDLGAKGSCQIGGNISTNAGGLRMVRYGSLHANVLGLEVVMPDGRVLNGLRGLRKDNTGYHLQHLFVGAEGTLGVVTGVSLLTPVLSPSVNLALLRLPDYAAVLRVFGKLKHSLGEILSAVEYFDETAWAVVSGDGAQGEEVERQVFGAEHVPKGVNMLIETSGSVAEHDEAKLSSLLEELLEGPDVLTGSLAQDETQLARMWELREGIAEACGKAGKVYKYDVSVPIQEWQNVLDTLRARAKKSGGRIERVVGFGHIGDGNLHINVVCGAYGKEVEQLLEPFMFELVASKNGSISAEHGLGVQKAKYIGYSKTPLEVELMRSIKHAFDLKGIMNPGKVILPASEVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>M5G854</accession>
    <name>M5G854_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_116428</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU02047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628944.1">
        <property type="nucleotide sequence ID" value="XM_040770200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G854"/>
    <dbReference type="STRING" id="1858805.M5G854"/>
    <dbReference type="GeneID" id="63685262"/>
    <dbReference type="HOGENOM" id="CLU_037162_0_2_1"/>
    <dbReference type="OMA" id="YSHAKMY"/>
    <dbReference type="OrthoDB" id="10249612at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="238"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU02047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="422" mass="46102" checksum="DB4A50292CB446D1" modified="2013-05-29" version="1">MADNYVHFHSSPPINRLSYLRHSTVFLNIALTHPRALFTLFHTGRPLLTGGKAAHVPFDRISPLVGQAPYFGQGEKEGESAEKGKWTEACRFRDRGVPLVFLGVLEDEGAALLPSEEVKQIASHEEIKGVPYWAVDLSDVDESWVQGVEELKDGKWSEPRSATSTYSHFDGAVFAVARSVVDWNARNGFCPACGGEGFSLWGGWKLGCSSNLPWAKNKNPYKGGPCPSGKGLHNFAHPRTDGVIIVAVVRESPTGEGEDILLGRQKSWPKGMYSTLAGFLEPGESVEDAVRREILEESGIVVGYVRYHSSQPWPYPANLMMGCYARAEVPTSAASDTQNPRAGIRLDLDNELEDARWFTRAEIRSILGDPDGTIIRQAPPANGAVSESTVRTEEGMKVRVPPRTAIAGVLISEWAAGNMANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8K6</accession>
    <name>M5G8K6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_105562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795858">
        <property type="protein sequence ID" value="EJU04505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631399.1">
        <property type="nucleotide sequence ID" value="XM_040768107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8K6"/>
    <dbReference type="STRING" id="1858805.M5G8K6"/>
    <dbReference type="GeneID" id="63683169"/>
    <dbReference type="HOGENOM" id="CLU_163494_0_0_1"/>
    <dbReference type="OMA" id="HTPENCT"/>
    <dbReference type="OrthoDB" id="3033280at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU04505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="124" mass="14577" checksum="02CDA779444599EF" modified="2013-05-29" version="1">MPEDPLFNDWKLFHAKFEGAFSDPDQSGTAHAKLEQLSQGNKTANEYIAMFRELAEYMNYNDVAHIRKFEQGLNRDLVDKIYSLTKMPEDLEEWYCYASHFHHQQRKLKASAPFKHTPENCTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>M5G8T9</accession>
    <name>M5G8T9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_79023</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629169.1">
        <property type="nucleotide sequence ID" value="XM_040776370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G8T9"/>
    <dbReference type="STRING" id="1858805.M5G8T9"/>
    <dbReference type="GeneID" id="63691432"/>
    <dbReference type="HOGENOM" id="CLU_002360_6_4_1"/>
    <dbReference type="OMA" id="FAYQFDF"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000268">
        <property type="entry name" value="ATPase 4 plasma membrane-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000004">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000005">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="739"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="774"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="851"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="881"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="76"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU02272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="998" mass="109504" checksum="E47D7B1AAE6021ED" modified="2013-05-29" version="1">MSEPITEKKEAGPPEPAPEPTSADNADTPAAETPAEKKREYKDFGHGDEEKNTHAKVDMSQIELKAEDLYDKEKVDLETLVMEDVFKLLQCGEDGLDPAEAARRLELFGPNKLEHEEQNPFLQFLSFMWNPLSWVMEAAALVAIALSNGGGMPPDWEDFVGIVLLLLVNSSIGFYEERGAGNAVKALMDSLAPKARVKRSGAWSEIESADLVPGDMVAFKIGDIVPADVRLTEAINVSIDQAALTGESLPQSKKVGDQCFSGSTCKQGEAEGVVISTGPNTFFGRAAKLVGQDDDTTGHLQKILAQIGSFCLVSIGLFVVLEIVILYPKYHYSYRRGLNDILVLLIGGIPIAMPTVLSVTLAVGAQQLAKHKAIVTRITAIEELAGVTILCSDKTGTLTTNKLTIDSNLVKTYGPFSAADVMLLAAYASRTENQDAIDACVVGAIPDPAKAREGIKLLDFKPFNPVDKRTEITYREESTGKLKRVTKGMTGIIVEHCTRNKTEEIENRLEADVEEFAARGLRALAVAYEELDGQDPAAEGNGFELIGLLAIFDPPRADTKQTIDDAIALGVKVKMVTGDQLAIAKETGRRLGLGDHMYPAKVLKDGPPVGGKHMSLDEMILDADGFAGVFPEHKYEIVKRLQGLGHLCAMTGDGANDAPALSRANVGIAVEGATDAARGAADIVLTEPGLSTIVHAIRGSRVIFQRMRNYSIYACSVTIRIVVCFAILAFAYQFDFPPFMILIIALLNDGTIMTLSVDRVLPSMTPDAWDLAEIFAFAVAYGIWLTLSTIALFMVLWHTEFFENHFHVDGYHDDVNNNHIHMILYLQVAIISQALIFVTRSHGFFFMERPSIALMVAFGIAQLISSIIAAYANWYFTDVEAISGGWIGIVWVWNIMWYIPLDYIKFAMKATVVKWLRERRERRIVDDRGEPLQRTQSRAASIHESLYSNRVSFIRRAVRTVGFGQGRTVRMSQNELQRFSSLQAQHAGATLARNPSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9F9</accession>
    <name>M5G9F9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PLP-dependent transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_75853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631769.1">
        <property type="nucleotide sequence ID" value="XM_040776162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9F9"/>
    <dbReference type="STRING" id="1858805.M5G9F9"/>
    <dbReference type="GeneID" id="63691224"/>
    <dbReference type="HOGENOM" id="CLU_010794_0_0_1"/>
    <dbReference type="OMA" id="KGWASRA"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000080">
        <property type="entry name" value="Bifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="582"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="834" mass="90800" checksum="F69C84D4AD2CEC6C" modified="2013-05-29" version="1">MALLFRNLRAHIVFGANTDVGKTILTTLLCRAAAQRTQAGDRVHYLKPVSTGPIEEADDEHVKRFAGGHGNISTACLYRYDDPVSPHLAAQRSHTIPTDVQLADSIRRDLTSFASNHTGEAWAFLETAGSPLSPSPSSSLQATALRPLRLPVVLVADPHLGGIGTTLSAYESLVIRGWSILGVVGWKESKWGNLEFLRRWFERETASGGEQVGVWELEAPPPRLEDKSEDARSMEGYYSSLSSSVQPLLSSLDERHQSRLSELDSMDARTRNSVWWPFTQHGQVREKEVMTIDSASGDFYSVYRSSSTSPQTPTDPSLLQQVYDGSASWWTQSLGHAHPSLALAAANAAARYGHVIFPSSTHAPALELAERLLRGEGEGWADRVFWSDDGSTGVEVALKMATRAVQLRMLQAASSTPTTIDNKSKDLGKELGVIGLKGSYHGDTIGAMDASEPSDYSLAVPWYRGRGFWFSPPAVSLQRSSAVITIPAIDPESPSKQEKVEHFASLQEIYDVPSRLSSPLAGHYRTEIERTLRRCVEQGQKFGALLLEPLLMGAGGMIFVDPLFQRVLADVVRSGSSYLGTSLPPTSASSNSNSNSSADSSAEYQPWTGLPVIHDSVFVGLSRLGCSPRHILQSNPDIAVYGKMLTGGLVPMSVTLSSSSIFSAFLGDKTQDALLHGHSYTAHPVGCSVANRALVLMEGVKRSPEWGGAQRAWGEQEGKRGIWSLWELDTLMRISELPCVERTMAMGTVLAITLQLPGSGYATVGGKRFLDFLRESWVEPGFDGVHSRALGRTVYFMSSLNTPGDTLRFIERALEKTLGAWGPVVNGETREEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9J1</accession>
    <name>M5G9J1_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_94355</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629426.1">
        <property type="nucleotide sequence ID" value="XM_040777217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9J1"/>
    <dbReference type="STRING" id="1858805.M5G9J1"/>
    <dbReference type="GeneID" id="63692279"/>
    <dbReference type="HOGENOM" id="CLU_002870_0_0_1"/>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="468"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="272"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="587"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="750"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="994"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="639"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU02532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1114" mass="124485" checksum="1DF564447D9AD823" modified="2013-05-29" version="1">MLKMNEGLLWGGRTQCIRVRNPMFSRKVGWNDTVASIMTSMGWTISSEVAWLAALGSSPSSTVPHPPIVDPDAQVLVPPSGVSQPDSPQRKKLLMAWIELGAFALVWRRRYPGIETAFRFSLEVHDTRETLEDMLGVNELYMDDLPRPVPQNKRGPFEALGLGPRWSPKILKTAYSMQCRCLLSKRTQFFDCLSHIYELTQNDQVGMLLAEERSRGRHTSLELSEAYAELGFGEDGELGMIGEDSDDNSVWEAFLYRVGQWSKLGQKDFIGPYAPPPGLPPGRETHGPYAPPPRFPPGREDVDMDSSASAGVGVAPSDEHQRGRSLTRAGAGTPHPSHSDWTTRALALPREDVKRNLKAALEVIAESRGSLELQRRLRGEAENKFGMDVETAYATLGVMKETDDEMVLAVFQTRCSDSPAMTDRMLDALRSIAQAWQSSRLLRFLETGNPESETPGHSTTSVPLEWPRGLDQLGNTCYLNSLLQYFYTIRELRENVVDNSKLVDENELIESRALETMRVGGRLVTKREIARSAEFVRLLGVLFTQLSVAETPSVTPELQLAKLALVTSQDEEEDKLLNHAIVASPVDTRQNTAPSSDATLVDAPMDVEPMGPHLPLADKSSTTILPEDEAAAPNGVPTAHSTPSATSGPDSAASSERKMSPPECAPSVLGKRERDSSVRPTRSMIYFGALADDPQTVKSPKRANTVPPSDMALDGESRSFRRAMTDPMDVDPAEPKPRSVSVDVEMKVDGPPEVSQQINGTNEPKRPPPPLPPRSSTKRVEVQSDSFMMFGRQHDVSECMDNCMFQIEAALKPDQEVAEGSLVKRLFYGKLRQRVTSDSSSTVHMRDDPFAHIHVNVGDEGFDLYDGLGGYFEDEVEYESRKSKMDVTLVELPQLLQVQLQRVQFNRETFQAYKSNAYVKFGESLYLDRFLESADPQKREHSKTIRKQLDECRNEIRALTQDSSGSFLQAMDFTRKFLDEQKQVDIPAWNTEASQTLESERHALNRRIEELRARAASLKEELEAVWADEKAAEYELCSVFIHRGKRNHAFGHYWLYSRVLPDHPDNWYKYNDSTITAVKKSDVLGDLTGSTANPYLLVYVRKGSDAIHTVHRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9R9</accession>
    <name>M5G9R9_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DACRYDRAFT_20592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU05035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631929.1">
        <property type="nucleotide sequence ID" value="XM_040771995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9R9"/>
    <dbReference type="STRING" id="1858805.M5G9R9"/>
    <dbReference type="GeneID" id="63687057"/>
    <dbReference type="HOGENOM" id="CLU_005732_2_0_1"/>
    <dbReference type="OMA" id="FYIARQT"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="435"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EJU05035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1066" mass="116636" checksum="8F2BC48E3F1696C2" modified="2013-05-29" version="1">MTHHAHSHSHGEKSVVALQRSYKYRAAVRPLLGRTSVVLCAFLLILVLAYVQDTRMRLYQLATTALGLLGLSDLRPATALTSNNLTDLVQWDPYSLYVMGQRIFLWSGEFHTWRLPVPDLWPDILQKAKAAGMNTISIYVHWGLTNPSNGTVDFTGVRALAPLFDAALASGLWVVVRPGPYINAETTAGGIAHWVTSEVAGHLRTNATDYESSWVPYIKGIIEECKPYQITEGGPIIAVQIDNEYTQADSPGWPGKAEYFEQLEALYRSEGIVVPLTYNDPGMGDNFAHGPGSVDIYGLDSYPQSFDCSNPYVWNPVVTNYYTYHMQTSPEEPFYIPEFQGGAFDPWGPNAPGYDNCRILTDSDFEQIFYLNLWANNVKMANFYMLYGGTSWGYLAFHGVYTSYDYGASIAETRILTPKFAELKREGLFLRSVPEFYKTDVIGNTTTSAVEVSSPLIFGTYLRNPDTGAGFYLVRQQNSSSLETVTFTLQANTSEGVITLPQDGSSITLTSRASKVIVHDLYFGSSHLLYSTAAILFAGTIGERDVLFLYGPATDSHEAAFKLSGTSSAIVNTSGPLDIQTSTIMDGTHTMVDVLPGTTGLSYIWDSPSSLVLFADSDTAGTFWAPTIAQSSATQFQHFYQFGTNETVLVGGPYLVRNASISGDTLELRGDLNDTTYLVVLAPSSVTKVTWNGDEVELDAGTSKVPSATGVLTATLTPKLTASSISLPSLNEWKYADSLPEVSGSYDDSYWTTADKYTTNIPYKPIYGDGPILYGCDYGYCEGAVLWRGHFQGTGNETGIELLINGGEAFAASVWLNSKFIGTTYGNSSNNLNILEETNTLFPFQGAVIPGVDNVVTVIQDNMGLNETQDDNADTSKCPRGIRGYEIRGHNYFTEWKVQGKLGGYTNFPDKTRGVFNEGGFYGERAGWHLPGFDDSAWESRSLSTGLSIAGVGMFRTTFDLNIPSGLDVPISFDFDSSFQPYRALLFVNGWQVGRRVANLGPQYSFPVQQGILDYSGTNTVAVLLWAMEDAGAHASLNMTINGVFEGGVGAITLDNPQWSSRGQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>M5G9U1</accession>
    <name>M5G9U1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_20018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632473.1">
        <property type="nucleotide sequence ID" value="XM_040771764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5G9U1"/>
    <dbReference type="GeneID" id="63686826"/>
    <dbReference type="HOGENOM" id="CLU_2426977_0_0_1"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU05579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="91" mass="10509" checksum="EBCF06602269D3AB" modified="2013-05-29" version="1">MIKYRVGAVFGHKWYVWDLNRLYGVTPTSSGDVSTWTGHCFKWVEYTPLALGADGRYRWSPVHRHLFAIASFDVGIEDTVKIYDTRFPHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GA13</accession>
    <name>M5GA13_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_106816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629651.1">
        <property type="nucleotide sequence ID" value="XM_040768342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GA13"/>
    <dbReference type="GeneID" id="63683404"/>
    <dbReference type="HOGENOM" id="CLU_075600_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU02757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="279" mass="31082" checksum="F1DB9C29FF7D4F7A" modified="2013-05-29" version="1">MLKTAATIVAGMCEDMEDPGFLPLVKYLDVKPFGNAVALLLNSPQSALICNLPEKWVQLFGLDQQAELAALSVLPSEDEEEDKDEKEFKAMLLGFLRSMVSLASPLVKAKKARAKAKEMTPAKPVMPHVNDGAIETLPTTRAHGRPMKEDTHNVGWMLEEMLVKVLLATMDEVLSYRLTPAFLPTFPSLSSFPREFSLTTHWTNILDTFWVRSVCIACIRKVMAPPPAPVEELFCLETPELVEETAKKPANKKKQKPKKCEQEDDKDSLGLSQKQSCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAA4</accession>
    <name>M5GAA4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="17">ATP-dependent metallopeptidase Hfl</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DACRYDRAFT_23146</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795866">
        <property type="protein sequence ID" value="EJU00823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040627720.1">
        <property type="nucleotide sequence ID" value="XM_040773119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GAA4"/>
    <dbReference type="STRING" id="1858805.M5GAA4"/>
    <dbReference type="MEROPS" id="M41.004"/>
    <dbReference type="GeneID" id="63688181"/>
    <dbReference type="HOGENOM" id="CLU_000688_9_2_1"/>
    <dbReference type="OMA" id="MSHFEWA"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141164">
        <property type="term" value="P:mitochondrial protein quality control"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000002">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000175">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="428"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EJU00823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="836" mass="90393" checksum="741E09C6A4CFF034" modified="2013-05-29" version="1">MALALAGPSQFIGSAQPFLQNLTSLIHSIPRPTAVTSTAPKQSQLSIAAPFQHFVPAVAEVLCTLPAAIPRPTHLQHIGSANLHSFRAPTATSVLLAAPLRLSRTVPQRRAYSTRSSFSPLLHVIKPAPSGPGAVRRQIQQVRPITWFPKAKPTLEPLVVARIGRAEADANANPDDVNKQVALFRELVAHGGKDGCERVIARWERTCQFSPQSPLIKSDAAFSVYCSALTNSGAAASVMPAAVRREQLLKTPVPVEAEVVPSTPESSSEVIAKNILATPKNAQPTMWGTTPIEATPAAATAPQPAVVSTVGNSTAEQMAAAVGSGAGIKGNPIHVVMEEPRGAMFWKFMRFVGITVLYGFILLTVLGLVLENSGLMKAGPRQTEFEPTPGKTVTFGDVHGVDEAKDELQEIVEFLKDPGKFSTLGGRLPKGVLLTGPPGTGKTLLARAVAGEAGVPFFFASGAEFDEMFVGVGAKRIRDLFAAARKKQPAIIFIDELDAIGGKRSPRDQHYMKQTLNQLLVELDGFSQTEGVIVIAATNFPETLDHALVRPGRFDRHVAVPLPDIKGRVQILKHHMREVTADIDVDAAIIARGTPGFSGADLQNMVNQAAIQASREGAKSVTLKHFEWAKDKILMGSERKSAYMPEDVKKLTAYHEGGHALVALYTQGAMPLHKVTCVPRGHALGLTLQLPDNDRQSVSFKEFLAEIDVCMGGRVAEELIFGKENVTSGARSDLQHASRTASNMVKHYGYSDKVGLVYHSDNDSYASPEKKNLIEMEVQRFLDEGHKRAKELLKLHEVELHRLAEALVKYETLDLEEVKKVIKGEDIRIGENLATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>M5GAD4</accession>
    <name>M5GAD4_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_104277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">DJM-731 SS1</strain>
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            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="241" mass="27685" checksum="1D596C2983BCF1A2" modified="2013-05-29" version="1">MTIRSSKPSGDLCDITPLATTPATTVPVAVPVEAKANPYALRPSTPSDIEEAGPNQPANGQTPYQSWPYHYVLPPREYYEDIMNMEILGRHLRWEHWVRQVETAYRIDFMASIYPPPPPPAPDPIRLSPYMSRTPYSMEELIFERSPSPPADYVNDIDIPLLTIGHPLLPDFRVEQEPYAVTTWHGWNWLNMHGELARLERIREERRMRAAEMRSERARNGHSHVETPSSVLPLLVKQEIE</sequence>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
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                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
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                <person name="Copeland A."/>
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                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
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                <person name="Lindquist E."/>
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                <person name="Lundell T."/>
                <person name="Martin R."/>
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                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
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                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
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                <person name="Cullen D."/>
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            <strain evidence="2 3">DJM-731 SS1</strain>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
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</entry>
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    <accession>M5GAT1</accession>
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        <lineage>
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        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
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                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
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                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
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                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="6">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="281"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
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            <end position="533"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
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        </location>
    </feature>
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    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU05994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="708" mass="79146" checksum="22A5901745E3EB46" modified="2013-05-29" version="1">MPSADHGQIFKATYSGIPVYEMICKNVAVMRRKSDKWLNATQILKVAGFDKPQRTRVLEREVQKGQHEKVQGGYGKYQGTWIPMDRGIALARQYNVEHLLRPIIDFVHAEASPPLAPKHITAPPAKPKRREVGGPPGLGIRASTGRGALVQGSDDESMRSGSPHISDEESTTPSPSVHSQSSRTPSPIASGNASDSEADHEMDIDGDMISPQVASSTRQPRKRKNGRVQSRPAQHLQLDESLKDTYEEIILDYFLSESQQTPDVLVNPPPDFDPNVVIDEEGHTALHWACALGRVKVVKLLLTAGADPFKTNKDGQPPLMRGVMFANNYDMRKFSELFEMLQRSVLHVDNFGRTIFHHVIDLALTKQKTHAARYYLETLITRMERFAQDLSDLLNLQDLEGDTPLTLAARARSKRLVKMLIDHGANPKVPNNDGKSAEDYILEDERFRASPPINYKPITTASTPLQLYYSRTAQKVAGDVTREMASLLESLAATYEGDMQEKERDLIQATSLLQNIQAEILESQRAVAQLKERAEGFDNVQQQLSELEGRLSRNMGRQYRLGFEKWMKDEEDREKAWLSSPDGMRYRLGMSSSQAKGKGKAESEEFSDLHALHTLPTDSAEIQRECEALREELRSYRTRREAAMQGFVQQLAEAGTGGRMAEYRRLIGGSLGIPPDEVDGLVDSLLEDLETEEPVVPAFPELTGIPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB40</accession>
    <name>M5GB40_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA stability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_49982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the endosulfine family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630106.1">
        <property type="nucleotide sequence ID" value="XM_040774955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB40"/>
    <dbReference type="STRING" id="1858805.M5GB40"/>
    <dbReference type="GeneID" id="63690017"/>
    <dbReference type="HOGENOM" id="CLU_101493_2_1_1"/>
    <dbReference type="OMA" id="TNSNMTQ"/>
    <dbReference type="OrthoDB" id="5949865at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358">
        <property type="entry name" value="ENDOSULFINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358:SF6">
        <property type="entry name" value="ENDOSULFINE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="122" mass="13036" checksum="36CC5CE1E3BA2C55" modified="2013-05-29" version="1">MLPAQRKKVDLSTMTEEEKKLFSLYGKLPNHKNVLMKMQKDRKYFDSGDYALSKAGVAPENAVGTAIPSPESYVGAPTLHPSAYHAISIPHASPPSSHPPLSASPNLPNSPAKESAPKAEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>M5GB70</accession>
    <name>M5GB70_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DACRYDRAFT_20066</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632534.1">
        <property type="nucleotide sequence ID" value="XM_040771781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GB70"/>
    <dbReference type="STRING" id="1858805.M5GB70"/>
    <dbReference type="GeneID" id="63686843"/>
    <dbReference type="HOGENOM" id="CLU_030988_12_0_1"/>
    <dbReference type="OMA" id="TWECGIP"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019789">
        <property type="term" value="F:SUMO transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="13">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EJU05640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="158" mass="18119" checksum="0E5CFCF821299034" modified="2013-05-29" version="1">MAGICRTRLSEERKQWRKDHPFGFYARPLKASDGSLDLLQWEVGIPGKPNTPWEGGIYKLTMTFPEDYPSKPPKCKFTPPLFHPNIYPSGTVCLSILDEEKGWKPAITFKQILLGIQELLNDPNVNDPAQSDAYTMFKNDKTAYERKVRSQARDNFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBB0</accession>
    <name>M5GBB0_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_99604</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH795860">
        <property type="protein sequence ID" value="EJU03332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630226.1">
        <property type="nucleotide sequence ID" value="XM_040777607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBB0"/>
    <dbReference type="STRING" id="1858805.M5GBB0"/>
    <dbReference type="GeneID" id="63692669"/>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="HQQWRQQ"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="219"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="112"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="453"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU03332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="609" mass="64569" checksum="64A334793EB3768B" modified="2013-05-29" version="1">MQASPTPSTLSSSSLSSSTLSSSTLSPASININTSVSPSGSPSPSSPLVRKKRNFKPLGLAISPVAPSPGSSLSMPSAMLAGVGGAIVSREATITPDHPLPTPPLLSVPKPPMGGGISTLRPPPLGGGGGGRRRPPPLLDVSKSKALPKEPKENGVHVSPARSASSAGGSSPFGYSSYPGGTPNTGSQRTNLQNKLSEQLATLEMGEKGERIELKVEDLKTICELGQGNGGTVSKVMHIPTGKTMARKLVLIDAKPAVRKQILRELQIMHDCRSTRIISFYGAFVADPHICICMEFADKGSLDQIYKRIGAIDIEVVAQIALAVLEGLTYLYDAHRIIHRDIKPSNILFNSAGQIKLCDFGVSGELINSIADTFVGTSTYMSPERIQGAQYTVKSDVWSLGITLIELALGRFPFSDDDSELEESDEEDEDADADADADIAHYIANGLSSASSVDTERSFADSEDSFGEGTLSPRRAPLAIPPPTISISSASTHSAADTDTTTTPQTSRGAPKLSAATNVKKNRRKSRGVSLQGGGMTMSILELLQHIVNEPAPTLPAAKYGQEARDFVAKLLEKKPEDRPSPKELLGDRWMIRAREEGYDLVAWAETIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBM7</accession>
    <name>M5GBM7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA 3'-terminal phosphate cyclase</fullName>
            <ecNumber evidence="2">6.5.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA terminal phosphate cyclase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DACRYDRAFT_86113</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. Likely functions in some aspects of cellular RNA processing. Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + ATP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633273.1">
        <property type="nucleotide sequence ID" value="XM_040776762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBM7"/>
    <dbReference type="STRING" id="1858805.M5GBM7"/>
    <dbReference type="GeneID" id="63691824"/>
    <dbReference type="HOGENOM" id="CLU_027882_0_1_1"/>
    <dbReference type="OMA" id="HAKTARW"/>
    <dbReference type="OrthoDB" id="25029at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.20:FF:000002">
        <property type="entry name" value="RNA terminal phosphate cyclase-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017770">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020719">
        <property type="entry name" value="RNA3'_term_phos_cycl-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03399">
        <property type="entry name" value="RNA_3prim_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF0">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005378">
        <property type="entry name" value="RNA3'_term_phos_cycl_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52913">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, RPTC, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01287">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="11">
        <location>
            <begin position="15"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="12">
        <location>
            <begin position="192"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="9">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="302"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005378-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005378-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EJU06379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="386" mass="41314" checksum="016ECD69F869D17E" modified="2013-05-29" version="1">MTSNTEHVVLDGSVLEGGGQILRNAMSYAAILRRSLRIDKIRVGRDQPGLKAQHAAGLVLVSQISEGSQFEGADVKSQSIIFQPGITTSGHYTADPQTAGSTTLLLQISLPCLICLPPDSYSTLTLRGGTNAVQAPQVDYIQRVFLPFLKQHFGIDVRLDIKQRGYWPKGGGELHVSVPSISGTLLPMDLKERGKVISVSGIAYVAGSLPQHLVHELRSSALDCMRDEGHLAGVHDITVDILKDQNCIGSGMGIVLVARTNTGCVLAGSALGVKGKSVKEVGEEAARELGKNLLEGGCVDEYMQDQMIIFLALAGGRSTIRTGPLTLHTKAAIWVAEQMTSARFTIEEEVDRHGVATNLIHCDGIGWSYIPPADRDPEETCICAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBU1</accession>
    <name>M5GBU1_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DACRYDRAFT_13772</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795856">
        <property type="protein sequence ID" value="EJU05910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040632804.1">
        <property type="nucleotide sequence ID" value="XM_040770995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GBU1"/>
    <dbReference type="STRING" id="1858805.M5GBU1"/>
    <dbReference type="GeneID" id="63686057"/>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OMA" id="ASITWHH"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EJU05910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="535" mass="60532" checksum="6270EB9635C33D03" modified="2013-05-29" version="1">MDIPFSSLALSLTQLYILISVLTSLLLLHLVRQYIVPLFSPLRNLKHPPSPSWIWGNMLQIFAAPSGELHREWEAEFGSVYAYRQLMNHAYTYPKPVAVQRSLARAVGEGLLIAEGEVHKRQRRIMNPSFSPAEIRELTPIFWDKAGELRDIWVKELDQAAAGGANDLVIDICKWMSRATLDIIGLAGFGYAFESLTDESNDLARAFSDLLILQRPSILILLLNLIPGFTLLPIKRNRVAAHSRDTLRRTGMELVKLKKEAVRQTLDGKRDEQEIGRKQVAGRDLLTALVRANMANDLPDEGRLDDEQVLAQISTFLLAGHETTSTAVIWALFALSKHQDVQTKLRKELQRYPESMPGMDELNNIPYLDWVVREVLRFHTPVGGTVRIADADDEIPVSTPYTDRHGVQRTSIPIKNGDGIYIPIKNVNRTPTLWGPDGESFNPERWAHVPEEATHIPGVWAHILSFLGGPRACIGYKFSVVEIKVFLYTIVREFEFEFADKTMEFEERSTIVTRPVIKGRVKEGPALPLRLRRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>M5GBZ4</accession>
    <name>M5GBZ4_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_114977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630496.1">
        <property type="nucleotide sequence ID" value="XM_040769920.1"/>
    </dbReference>
    <dbReference type="STRING" id="1858805.M5GBZ4"/>
    <dbReference type="GeneID" id="63684982"/>
    <dbReference type="HOGENOM" id="CLU_002853_0_0_1"/>
    <dbReference type="OMA" id="WLTITHD"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF54">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1682"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="3">
        <location>
            <begin position="469"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="3">
        <location>
            <begin position="973"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="864"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1325"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1580"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1639"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU03602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="1756" mass="191666" checksum="B61EBCEBB3419FC8" modified="2013-05-29" version="1" fragment="single">MSEGSRIRESWLVALTDAQARFRSLLSAPASDWKRVPLSQGPAKQDGPASYSSKGKSRAGTTLSDVAVHRRQGKDGEVYRAMLDVFTDEGGLLDADNWKAVLQTPELRKSWDPIVDGSHLVELLDPDTRICKTEFKLGWPANPRDAITIARIFSDSSALIDISTSLPRSSDDPAYLRPSPPYVRSNVRLSSWCIQFIPGTSSPTESSSRAPSSARVRLMCFWQHDLNAVWGMAGLGIGQHLPVLLLGLVESVRQKGNRIPRFIGYGLGISIFSIVYGEAGREALVMEYAIIQPEDDEFEVGGPKEKTLKEVQLQKERRRLERTIELGLPSTHGWDLQVTVKAPSEETAAAPWVAQAGRITQGGSSADSARLVFRIVHPPPPTDSIVSVKLIAELAGGVPGIRVNGLPQEITSFESRDPISFAINKDTFGDVSDVQAISIHTVNTIESAESGPSSQVSKRPIIRTATERSPAAEKAILSLVRRNYIYFTSLLQEPEAKWKYITESRGVTVTQLDSIDPTLVVYRAAAVFVGVTLWDLFSMVDTPGTRSQWDKSFDDAVFLEDVNELTDLWHWKTKGVWPVMPRDSTLLKTVYKSSSSVHIFAFSTEDTNLFPSIPPTDPAFIRSQIDLQGWAIEALSPTTTQITLLDQSDPKGWSNKAYIPGQMIATLGGMGEFAIKLGSPPMITRLGGARLTRSRYEFDKGLFRIEYEGSEQRRSPNVEPEAERSKEVIPASPTSAEHPPPDLPPVTSPQPLDLIPKLECEIRIDADSWASHIELVIDPPPQSVSCLRRHKLATKGGGLWITIEHDAIMVGEERVLVQIKKVPGSIREKAVVTVNGAKVKVDVVSLPEAEIKSRSRQKRVKPIRMPLDQPPVPGLRRKRTDTEDGEMSGAETVTLRRRQARMSVQPFTSPVARWFSMAVEQASSTTAAATAAMGPTPASRLKEDTTSTTTPLRAALGALSIVQRLQAIPVAHWISITENNGFSVSRRIFEEISPTIPIHRSEKVIEGISAEDVAHLISDLHSRKQWDDRLESSAVVEEYGFGCSTAFLALRTTFPFQNRGFYVAAITGRAPSGQRSNKADADSPLSGSSGWVSADAVSTIYHAMASFPESALASNMSPAKINSAGLSIGHIHLHGWVIETLDPYTTENFAIPSTRVIQFSAIDFAGQIPLAVNGMLNSALPHSILAIQKAVKTQPPLPSLRWPAKALSVSRDEEVTTGAEWLLDISDEQRTLVNQSFAPSSKTFKARVIIKPRRPGPVTRPSTPFDKDKTPTMPTTKLLEPSATPKMVVEDGSARTSPIPFSSASTLTVNGSASDLGSVRLSRGHVRTSSLTVRPSSLSPPLQRPRVGSSAPKPSMLANVPRTLANLDFVLGEVLLYPDLYGLSYRIDVDYELLSGSNSKPLDLAASLKSPTPSDLQIRASVYTMPPSPLHSHAMDLSVATPPTKHLLRFTLPTALYYTSGLDPLSIDDASDGHGPEFPTWLKDLEEKGAVVSITITPNDSISRSGILFQGKPLKVSGENESVDVLGTEELEDNRAGKLAKLRRGSASDGQLIPKELRKPLTVAMDFVKEDTITADPAVGDAQIADPGNEGKPADTDTSEHVTTVDTVDNKPAGQLTLLGFFNTNTLLRLTPSITIPSFMSSPLPTRPGTPSKGTRPAISRRTSGSPLGTVSWKHVLHDPQFSLKFVVVTAIIAFLLGSLIRSLLSPADFMFYPSQNKNDSLQGEDGGWREVKRLIEMKWILWGWDAVIFAVVRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>M5GCP0</accession>
    <name>M5GCP0_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_22325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795863">
        <property type="protein sequence ID" value="EJU01888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040628785.1">
        <property type="nucleotide sequence ID" value="XM_040772744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GCP0"/>
    <dbReference type="STRING" id="1858805.M5GCP0"/>
    <dbReference type="GeneID" id="63687806"/>
    <dbReference type="HOGENOM" id="CLU_022670_4_2_1"/>
    <dbReference type="OMA" id="SIAKEPH"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="26"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="117"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU01888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="355" mass="36978" checksum="2FBDE8B2AA60A534" modified="2013-05-29" version="1">MPSSPPNSPPPNPASPRGQSSANPAEILTLRALVSTKDAGIIIGKAGRNVADLRESTGVKAGVSKVVPGVHERVLSVTGPVEAVAKAYTLIASQLLSPPAPPSPPQTPPPSPPNQASTLTLRLLISHNLMGTLIGRSGLKIKSIQDASGVRMVAAKEMLPQSTERVVEVIGDAESIGRAVEEVGRCLVEDWERGVGTVLYHPGAAVDPSLAMQHGASHVSPRRTNGQAPAFGTSGRRQSIGQQTSLPAAAASVLAPASPTSNAGNQPIRTQNISIPSDMVGCIIGRGGAKITEIRRLSGSKISIAKQPHDETGERMFTITGTGESNEKALFLLYNQLEGEKERRVGREAMIAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>M5GD17</accession>
    <name>M5GD17_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DACRYDRAFT_19666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633454.1">
        <property type="nucleotide sequence ID" value="XM_040771610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GD17"/>
    <dbReference type="STRING" id="1858805.M5GD17"/>
    <dbReference type="GeneID" id="63686672"/>
    <dbReference type="HOGENOM" id="CLU_094365_1_0_1"/>
    <dbReference type="OMA" id="TPSKWWL"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1760.10:FF:000002">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EJU06560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="181" mass="20455" checksum="28A1B378905F1916" modified="2013-05-29" version="1">MPAYHSAFNEEPDVRTVGNTAVLPIKTRIRGPAPLMADSNQPDIIDETLDLFRANSLFRNFEIKGPADRLLIILILYISDCLLKVQASRVPPNQNEAGKMLNTFAVDNFPLPGDAGFPLNAHYQAPASRIDADQLRSYLVQVRQEMSARLVERLYADGTGKPSKWWMCFTKRRFMQRSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDG7</accession>
    <name>M5GDG7_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_22041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795862">
        <property type="protein sequence ID" value="EJU02378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629272.1">
        <property type="nucleotide sequence ID" value="XM_040772653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDG7"/>
    <dbReference type="GeneID" id="63687715"/>
    <dbReference type="HOGENOM" id="CLU_2904139_0_0_1"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="62" mass="6702" checksum="FD95CDF973D1FC2F" modified="2013-05-29" version="1">MASQTAVPLRPSAENSIHAKYVRAPPPAQTLRKILPHALSLFPYLSHPASRIPPWLPASPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDN7</accession>
    <name>M5GDN7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase PFA4</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein S-acyltransferase</fullName>
            <shortName evidence="11">PAT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protein fatty acyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PFA4</name>
        <name evidence="15" type="ORF">DACRYDRAFT_106638</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11 12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDN7"/>
    <dbReference type="STRING" id="1858805.M5GDN7"/>
    <dbReference type="HOGENOM" id="CLU_027721_9_0_1"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03199">
        <property type="entry name" value="DHHC_PAT_PFA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033682">
        <property type="entry name" value="PFA4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="91"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="269"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="422"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="513"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="active site" description="S-palmitoyl cysteine intermediate" evidence="11">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EJU02573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="647" mass="72588" checksum="53834BCAA99742F4" modified="2013-05-29" version="1">MAGVLGRVLVVVTCFLIAFIAYSSQLFVFYPWYGYTVSVDFIWAMLPFNILVGLIWWNYYLVVWTDPGRIPDGWVPQTGEGQSFEVKQGNGKLRYCRTCKVYKPPRSHHCRECNACTLRMDHHCPWVNNCVGHKNYASFMRFLFFVDLACTYHMTLFMRMFSPTTSQVVWAALNFATCVPVLLAVGLFSLYHFYLLATNTTTIEAWEKDKVAMLVRRGRIEKIKFPYNLGMLQNLRYVLGPNPLFWCWPTLSVQGDGLSYPVEAGTGEWNAHSGKERSSPLAASPPASHPYPYPNPPPANSHGYSNGLRNPVAGNGGVALHENGHDAYARSWGRGGDDDAGDTIDMLMPFSVEEHVPFIWPPKDPSSYYEPRPMPESPWTYGSGVNPHLEPSNTRLRARAANKRNKAANKRTKRQPDAFTTFLKSLDNEEPNSTSPISSEDDSDPKENHGLVRARRAARNGDQITDEDADVDAYDTRTGRPKTRRGSEGWEVKPLTPWAREEIVRKYAARRGLEREGEEPVPDSAVGNQVQLPNTRDDDALLGATTMPAHRPRSDLGDKTRPSTLPPPDKYNRYVPSAEDSSSSEEDNAEDEGVFRDRVWEQHIDAWEGRVIVNESAGGIATNGMAEEIHGLAEEIHGLAETDSALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>M5GDU8</accession>
    <name>M5GDU8_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DACRYDRAFT_21704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629592.1">
        <property type="nucleotide sequence ID" value="XM_040772509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GDU8"/>
    <dbReference type="STRING" id="1858805.M5GDU8"/>
    <dbReference type="GeneID" id="63687571"/>
    <dbReference type="HOGENOM" id="CLU_1726624_0_0_1"/>
    <dbReference type="OrthoDB" id="107110at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EJU02698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="152" mass="16921" checksum="EDC7B49846171A73" modified="2013-05-29" version="1" fragment="single">KKLPDCLETLVTELCGSGIIPRRDIGELAARLLLLCPRIAASDATFQDPIPLPNITLVTYLEALLGPVLDSDFKETFDNTWVNFHHWVVLSGAGALPNNLDRTTLANLWARGAAIQWWYNQASVHLLFITYRGSNEPNALFDPRNLSAVHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>M5GE19</accession>
    <name>M5GE19_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_106982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795861">
        <property type="protein sequence ID" value="EJU02898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040629792.1">
        <property type="nucleotide sequence ID" value="XM_040768363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GE19"/>
    <dbReference type="STRING" id="1858805.M5GE19"/>
    <dbReference type="GeneID" id="63683425"/>
    <dbReference type="HOGENOM" id="CLU_569886_0_0_1"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="216"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="211"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU02898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="479" mass="52752" checksum="A623F3C726C3C4E4" modified="2013-05-29" version="1">MSNQYYQSTPSRPHSRPPSTLTIDPPPLNSRRSSSLNLISPNQDPLDEDRARRTYEEGDMGEMKQALWSMLTRVDELSAQVHSLLTEQEDLNTSLTVAKSNLTLALSNNEMLEEALARTPASAQPLGWRRHSARDGVHREVQSAAPDYPQRRSWDTVGSIDSSPEELTFWQSLTRPASAAPRPSTPHPPLTAIGVMRERQSLTSASTPALLDGTLVEVERLRDALRNERAQSESLKKEKAGLEQEIESLSQALFEEANKMVSDERKRRAAAEIDLQEMRDEREAMKRTLRMVEEENRKLRRGEALPGLALSGNTNTSTTPELVYPSPSRALGYEQADKDMTPTQPERPPSDAASVRSEMLDDGVRIDRVWLDAISPPVGSFPRPLNLVSGFGTTPPNETSSLAAAYPNHPTLNLRRSPGQQHTSLPPSPNDQAGGYFPQPGSYLSAGNQPGYGWAGGNGNGMNGVGEGLRRLELVPKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GET7</accession>
    <name>M5GET7_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_99186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_040777573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GET7"/>
    <dbReference type="STRING" id="1858805.M5GET7"/>
    <dbReference type="GeneID" id="63692635"/>
    <dbReference type="HOGENOM" id="CLU_481477_0_0_1"/>
    <dbReference type="OMA" id="KMNETEW"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="50"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="157"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="461"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="350"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU03578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="566" mass="62178" checksum="426D3B6BFA1B5A97" modified="2013-05-29" version="1">MHSLISAVRLTRRIPAIHKSLLIHRPSARFMGNVSPAQSLAAAETSSKNRRVFVLNLPYTATMDKVKEFMETRAGPVTHAEILTTPEGESKGCAVVEFEGQEMAEKAIASISMQVFDGRSVFVRPVGHDLVVGERDRKMNETEWQDQSDMGFGTQPYQLYIGNVPPSFSWQDLKDVFKPFGPVNHCNVSSKRVASATEPIWGTLQLQSAAHAQRAMNHFADAARKSSIGALVVLPWEDRPRDVDVSLLNDAARRSLRPNKGDGSAPAPAWGGPVTSQAGQVGQPRQPYGFAQPGQATFSAPGRFPPGQVQQLPQQPQQEQQHSPGQAQPLPNTWSNYPYPYPYAYPPPPSSLGQGWPSPAGTPPPGTPPQNAYPAPPQGWPSHPPQGYPPYQVPYPYNYTYPPSPVTTPSPDSSSSATPSPDSAIPPPVEQEKNIWKAPTGPRAAPELFRHRTALHTGAKTQIVVKFFPNETDEEDLVDLFTSTGAQVVGVEILRTERIRNMGIVQFSTPDEAQAAVQTFHGYNYGGRGLALRMVNEPFNFSAKAWAPDREKLVEEEREKSWKDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>M5GF86</accession>
    <name>M5GF86_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_115230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795859">
        <property type="protein sequence ID" value="EJU03943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040630837.1">
        <property type="nucleotide sequence ID" value="XM_040769959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GF86"/>
    <dbReference type="STRING" id="1858805.M5GF86"/>
    <dbReference type="GeneID" id="63685021"/>
    <dbReference type="HOGENOM" id="CLU_003433_2_2_1"/>
    <dbReference type="OMA" id="LVTWQQI"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EJU03943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="437" mass="47667" checksum="572623161F3A1E9A" modified="2013-05-29" version="1">MSATLDPLVECRPHFPALTGDYIFADSAGGSQCLKAAADEVADYLINSNVQHGADYSVSVKATQRVQMGVDATRILMNAESSDEIVFGSSSTQLIENLARAYTDLESDDEIVVSLTDHEANTGPWTRLAARYNLKFHIWTPKPLNPSNPFSVSLTLDGLIPLLSSKTRIVAFTACSNILGELTDVKGFVKAIREKTRGGKGERRQARGAEVCVDCVAYAPHRRIDVQDWDVDYCVFSYYKVYGPHASALYARLSSLATLSSLAHFFFTPAPAKAMKLQPGGAGYELTYGTSMVLPYIRSLGGPNGDLDVAFKRMAGQEGLLVTKLIGYLTSDASYKKGVRIVGYEGIDSLKRAPTISFIVVGDDGLTKKVQSKDIVATFDKKGNMGIRWGHFYAYRLCSALMGESSAVDGVVRVSFVHYNTTKEVDRLIAVFEEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GFV6</accession>
    <name>M5GFV6_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DACRYDRAFT_92542</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="JH795855">
        <property type="protein sequence ID" value="EJU06617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040633511.1">
        <property type="nucleotide sequence ID" value="XM_040777085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GFV6"/>
    <dbReference type="STRING" id="1858805.M5GFV6"/>
    <dbReference type="GeneID" id="63692147"/>
    <dbReference type="HOGENOM" id="CLU_036234_0_0_1"/>
    <dbReference type="OMA" id="GIHKWIA"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="4">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
        <location>
            <begin position="195"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EJU06617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36331" checksum="92E269745EAEAB99" modified="2013-05-29" version="1">MHTKGKSKEDFSKAASSSQPTKPTKAHKPKSSKSKPANLPQTTHYCYLRAHSGSSTQGGLPTGRTLFVVNLPAVCGERELRDVVGRWGVVERIVWRGDELHPDSDGEDKGEEAMADEDDDDDDMEETRKPQPSALPSIPPLPSLPSIPHATSLSAHVVFLDPSSLTRALQAHPPIPLRPLALGLTHYLALHAALRPSLPMVRKHADAYIAAWETREEEKRRAQKVGVEHVDADGFTLVTRGGRHGRASAGGVGVASRSFELQHRAGAEQLQKKKRARRAAGVVPDFYRFQLREKKREEFIKLRKVFEEDKKKVNKMREERRFRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-04-02" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG02</accession>
    <name>M5GG02_DACPD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DACRYDRAFT_75494</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DJM-731 SS1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631527.1">
        <property type="nucleotide sequence ID" value="XM_040776140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG02"/>
    <dbReference type="STRING" id="1858805.M5GG02"/>
    <dbReference type="GeneID" id="63691202"/>
    <dbReference type="HOGENOM" id="CLU_012062_27_1_1"/>
    <dbReference type="OMA" id="YKPVWID"/>
    <dbReference type="OrthoDB" id="407442at2759"/>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EJU04633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="147" mass="15838" checksum="86ABD8AD2B7E3C64" modified="2013-05-29" version="1">MEQGTKTKRTVFIGNLGSEIDQNALVAAFSTFGDIVDATIPSDLARDNVNQTYRGIAFLTYTSPADAQDAIDNMDLNIFRERILRVSLARPIKGPAGLGGGLGNRAIWESEEWLKDHSEGGPGVGKADANANANAETGEEQEEQEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2025-06-18" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>M5GG65</accession>
    <name>M5GG65_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="3">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">DACRYDRAFT_87167</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C."/>
                <person name="Hori C."/>
                <person name="Igarashi K."/>
                <person name="Jurgens J.A."/>
                <person name="Kallen N."/>
                <person name="Kersten P."/>
                <person name="Kohler A."/>
                <person name="Kuees U."/>
                <person name="Kumar T.K.A."/>
                <person name="Kuo A."/>
                <person name="LaButti K."/>
                <person name="Larrondo L.F."/>
                <person name="Lindquist E."/>
                <person name="Ling A."/>
                <person name="Lombard V."/>
                <person name="Lucas S."/>
                <person name="Lundell T."/>
                <person name="Martin R."/>
                <person name="McLaughlin D.J."/>
                <person name="Morgenstern I."/>
                <person name="Morin E."/>
                <person name="Murat C."/>
                <person name="Nagy L.G."/>
                <person name="Nolan M."/>
                <person name="Ohm R.A."/>
                <person name="Patyshakuliyeva A."/>
                <person name="Rokas A."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Sabat G."/>
                <person name="Salamov A."/>
                <person name="Samejima M."/>
                <person name="Schmutz J."/>
                <person name="Slot J.C."/>
                <person name="St John F."/>
                <person name="Stenlid J."/>
                <person name="Sun H."/>
                <person name="Sun S."/>
                <person name="Syed K."/>
                <person name="Tsang A."/>
                <person name="Wiebenga A."/>
                <person name="Young D."/>
                <person name="Pisabarro A."/>
                <person name="Eastwood D.C."/>
                <person name="Martin F."/>
                <person name="Cullen D."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
            <dbReference type="PubMed" id="22745431"/>
            <dbReference type="DOI" id="10.1126/science.1221748"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DJM-731 SS1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer. Also forms a small population of homotetramers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="3"/>
    <dbReference type="EMBL" id="JH795857">
        <property type="protein sequence ID" value="EJU04948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_040631842.1">
        <property type="nucleotide sequence ID" value="XM_040776799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="M5GG65"/>
    <dbReference type="STRING" id="1858805.M5GG65"/>
    <dbReference type="GeneID" id="63691861"/>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_1"/>
    <dbReference type="OMA" id="IWQSFAV"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000030653">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7 16" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 16" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="18">
        <location>
            <begin position="208"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="236"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EJU04948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000030653"/>
        </source>
    </evidence>
    <sequence length="542" mass="60126" checksum="6A62772616335D45" modified="2013-05-29" version="1">MATEIHDAYDSVLILDFGSQYSHLITRRCREINVYCEMLPCTQKMADLDWKPKGIILSGSPFSVYDEGAPRVDPAVFDYGVPVLGVCYGLQEIALNHGGKVDPCTHREYGFATLEVVKLGAGHELADKLFEGICGEMQVWMSHGDQVTALPPHYNVIGKTPTAPYAAIAHESKPIFGVQFHAEVTHSPRGKEVIKSFVLSICKCKPNWTMETFIDKEIARIRQICGEKGRVIGAVSGGVDSSVAAKLMHEAIGDRFHAVMVDNGVLRENEAIQVHKMLFEDLGVNLTVVDASDRFLTKLEGVEDPEQKRKIIGNMFIHVFEEEAAKIEAAAEKELEENPKAEAKGKIEWLLQGTLYPDVIESISFKGPSATIKTHHNVGGLLKDMKLKLIEPLRELFKDEVRALGRLLGIPAHLVGRHPFPGPGLAIRILGPVTREQVKIAQKADTIYIDEIRRAGLYDQISQAFAVLLPVKAVGVQGDKRTYDQVVVLRAVQTEDFMTADWYVFPPEVLRRISSRITNEVAGVNRVTYDISSKPPGTVEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-05-29" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>M5GGE2</accession>
    <name>M5GGE2_DACPD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAR-17a/AIG1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DACRYDRAFT_74529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Dacryopinax primogenitus (strain DJM 731)</name>
        <name type="common">Brown rot fungus</name>
        <dbReference type="NCBI Taxonomy" id="1858805"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Dacrymycetes</taxon>
            <taxon>Dacrymycetales</taxon>
            <taxon>Dacrymycetaceae</taxon>
            <taxon>Dacryopinax</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2012" name="Science" volume="336" first="1715" last="1719">
            <title>The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.</title>
            <authorList>
                <person name="Floudas D."/>
                <person name="Binder M."/>
                <person name="Riley R."/>
                <person name="Barry K."/>
                <person name="Blanchette R.A."/>
                <person name="Henrissat B."/>
                <person name="Martinez A.T."/>
                <person name="Otillar R."/>
                <person name="Spatafora J.W."/>
                <person name="Yadav J.S."/>
                <person name="Aerts A."/>
                <person name="Benoit I."/>
                <person name="Boyd A."/>
                <person name="Carlson A."/>
                <person name="Copeland A."/>
                <person name="Coutinho P.M."/>
                <person name="de Vries R.P."/>
                <person name="Ferreira P."/>
                <person name="Findley K."/>
                <person name="Foster B."/>
                <person name="Gaskell J."/>
                <person name="Glotzer D."/>
                <person name="Gorecki P."/>
                <person name="Heitman J."/>
                <person name="Hesse C.
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